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Editing gene: PPP1CA (CAeditome ID:5499)

Gene summary for PPP1CA

Gene summary

Gene information	Gene symbol	PPP1CA
	Gene ID	5499
	Gene name	protein phosphatase 1 catalytic subunit alpha
	Synonyms	PP-1A\|PP1A\|PP1alpha\|PPP1A
	Cytomap	11q13.2
	Type of gene	protein-coding
	Description	serine/threonine-protein phosphatase PP1-alpha catalytic subunitprotein phosphatase 1, catalytic subunit, alpha isozymeserine/threonine protein phosphatase PP1-alpha 1 catalytic subunittesticular tissue protein Li 155
	Modification date	20210518
	UniProtAcc	P62136
	Context	- 18204081(PPP1CA contributes to the senescence program induced by oncogenic Ras)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
PPP1CA	GO:0000781	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	24270157
PPP1CA	GO:0098641	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	25468996
PPP1CA	GO:0016311	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	22311981
PPP1CA	GO:0005634	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	11739654
PPP1CA	GO:0005654	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	0000052
PPP1CA	GO:0005737	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	11739654
PPP1CA	GO:0005829	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	0000052
PPP1CA	GO:0005886	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	0000052
PPP1CA	GO:0005912	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	25468996
PPP1CA	GO:0072357	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	20516061

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RNA A-to-I events for PPP1CA

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000172531.13

RNA A-to-I editing events in Cancer.

CAediting_832157(67399988, -), CAediting_832158(67400015, -), CAediting_832159(67400037, -), CAediting_832160(67400054, -), CAediting_832161(67400106, -), CAediting_832162(67400238, -), CAediting_832163(67400246, -), CAediting_832164(67402437, -), CAediting_832165(67402438, -), CAediting_832166(67402439, -), CAediting_832167(67402442, -), CAediting_832168(67402485, -), CAediting_832169(67402497, -), CAediting_832170(67402498, -), CAediting_832171(67402505, -), CAediting_832172(67402506, -), CAediting_832173(67402514, -), CAediting_832174(67402520, -), CAediting_832175(67402524, -), CAediting_832176(67402546, -), CAediting_832177(67402579, -), CAediting_832178(67402582, -), CAediting_832179(67402584, -), CAediting_832180(67402585, -), CAediting_832181(67402586, -), CAediting_832182(67402588, -), CAediting_832183(67402597, -), CAediting_832184(67402610, -), CAediting_832185(67402621, -), CAediting_832186(67402626, -), CAediting_832187(67402627, -), CAediting_832188(67402645, -), CAediting_832189(67402658, -), CAediting_832190(67402659, -), CAediting_832191(67402681, -), CAediting_832192(67402689, -), CAediting_832193(67402703, -), CAediting_832194(67402786, -), CAediting_832195(67402820, -), CAediting_832196(67402821, -), CAediting_832197(67402846, -), CAediting_832198(67402847, -), CAediting_832199(67402848, -), CAediting_832200(67402860, -), CAediting_832201(67402885, -), CAediting_832202(67402899, -), CAediting_832203(67402901, -), CAediting_832204(67402927, -), CAediting_832205(67402938, -), CAediting_832206(67402943, -), CAediting_832207(67402953, -), CAediting_832208(67402956, -), CAediting_832209(67402957, -), CAediting_832210(67402965, -), CAediting_832211(67402983, -), CAediting_832212(67403228, -), CAediting_832213(67403230, -), CAediting_832214(67403262, -), CAediting_832215(67403268, -), CAediting_832216(67403288, -), CAediting_832217(67403453, -), CAediting_832218(67403454, -), CAediting_832219(67403481, -), CAediting_832220(67403525, -), CAediting_832221(67403531, -), CAediting_832222(67403539, -), CAediting_832223(67403540, -), CAediting_832224(67403550, -), CAediting_832225(67403556, -), CAediting_832226(67403559, -), CAediting_832227(67403566, -), CAediting_832228(67403576, -), CAediting_832229(67403580, -), CAediting_832230(67403601, -), CAediting_832231(67403605, -), CAediting_832232(67403606, -), CAediting_832233(67403610, -), CAediting_832234(67403625, -), CAediting_832235(67403684, -), CAediting_832236(67403686, -), CAediting_832237(67413025, -), CAediting_832238(67413051, -), CAediting_832239(67413056, -), CAediting_832240(67413065, -), CAediting_832241(67413100, -), CAediting_832242(67413104, -), CAediting_832243(67413107, -), CAediting_832244(67413503, -), CAediting_832245(67413848, -), CAediting_832246(67413856, -), CAediting_832247(67413862, -), CAediting_832248(67413877, -), CAediting_832249(67413901, -), CAediting_832250(67413913, -), CAediting_832251(67413922, -), CAediting_832252(67413925, -), CAediting_832253(67413956, -), CAediting_832254(67413990, -), CAediting_832255(67413992, -), CAediting_832256(67414004, -), CAediting_832257(67414014, -), CAediting_832258(67414052, -), CAediting_832259(67414057, -), CAediting_832260(67414066, -), CAediting_832261(67414083, -), CAediting_832262(67414123, -), CAediting_832263(67414135, -), CAediting_832264(67414170, -), CAediting_832265(67414220, -), CAediting_832266(67414251, -),

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RNA editing positional annotations for PPP1CA using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_832157	chr11_67399988_-	ncRNA_intronic
CAediting_832158	chr11_67400015_-	ncRNA_intronic
CAediting_832159	chr11_67400037_-	ncRNA_intronic
CAediting_832160	chr11_67400054_-	ncRNA_intronic
CAediting_832161	chr11_67400106_-	ncRNA_intronic
CAediting_832162	chr11_67400238_-	ncRNA_intronic
CAediting_832163	chr11_67400246_-	ncRNA_intronic
CAediting_832164	chr11_67402437_-	ncRNA_intronic
CAediting_832165	chr11_67402438_-	ncRNA_intronic
CAediting_832166	chr11_67402439_-	ncRNA_intronic
CAediting_832167	chr11_67402442_-	ncRNA_intronic
CAediting_832168	chr11_67402485_-	ncRNA_intronic
CAediting_832169	chr11_67402497_-	ncRNA_intronic
CAediting_832170	chr11_67402498_-	ncRNA_intronic
CAediting_832171	chr11_67402505_-	ncRNA_intronic
CAediting_832172	chr11_67402506_-	ncRNA_intronic
CAediting_832173	chr11_67402514_-	ncRNA_intronic
CAediting_832174	chr11_67402520_-	ncRNA_intronic
CAediting_832175	chr11_67402524_-	ncRNA_intronic
CAediting_832176	chr11_67402546_-	ncRNA_intronic
CAediting_832177	chr11_67402579_-	ncRNA_intronic
CAediting_832178	chr11_67402582_-	ncRNA_intronic
CAediting_832179	chr11_67402584_-	ncRNA_intronic
CAediting_832180	chr11_67402585_-	ncRNA_intronic
CAediting_832181	chr11_67402586_-	ncRNA_intronic
CAediting_832182	chr11_67402588_-	ncRNA_intronic
CAediting_832183	chr11_67402597_-	ncRNA_intronic
CAediting_832184	chr11_67402610_-	ncRNA_intronic
CAediting_832185	chr11_67402621_-	ncRNA_intronic
CAediting_832186	chr11_67402626_-	ncRNA_intronic
CAediting_832187	chr11_67402627_-	ncRNA_intronic
CAediting_832188	chr11_67402645_-	ncRNA_intronic
CAediting_832189	chr11_67402658_-	ncRNA_intronic
CAediting_832190	chr11_67402659_-	ncRNA_intronic
CAediting_832191	chr11_67402681_-	ncRNA_intronic
CAediting_832192	chr11_67402689_-	ncRNA_intronic
CAediting_832193	chr11_67402703_-	ncRNA_intronic
CAediting_832194	chr11_67402786_-	ncRNA_intronic
CAediting_832195	chr11_67402820_-	ncRNA_intronic
CAediting_832196	chr11_67402821_-	ncRNA_intronic
CAediting_832197	chr11_67402846_-	ncRNA_intronic
CAediting_832198	chr11_67402847_-	ncRNA_intronic
CAediting_832199	chr11_67402848_-	ncRNA_intronic
CAediting_832200	chr11_67402860_-	ncRNA_intronic
CAediting_832201	chr11_67402885_-	ncRNA_intronic
CAediting_832202	chr11_67402899_-	ncRNA_intronic
CAediting_832203	chr11_67402901_-	ncRNA_intronic
CAediting_832204	chr11_67402927_-	ncRNA_intronic
CAediting_832205	chr11_67402938_-	ncRNA_intronic
CAediting_832206	chr11_67402943_-	ncRNA_intronic
CAediting_832207	chr11_67402953_-	ncRNA_intronic
CAediting_832208	chr11_67402956_-	ncRNA_intronic
CAediting_832209	chr11_67402957_-	ncRNA_intronic
CAediting_832210	chr11_67402965_-	ncRNA_intronic
CAediting_832211	chr11_67402983_-	ncRNA_intronic
CAediting_832212	chr11_67403228_-	ncRNA_intronic
CAediting_832213	chr11_67403230_-	ncRNA_intronic
CAediting_832214	chr11_67403262_-	ncRNA_intronic
CAediting_832215	chr11_67403268_-	ncRNA_intronic
CAediting_832216	chr11_67403288_-	ncRNA_intronic
CAediting_832217	chr11_67403453_-	ncRNA_intronic
CAediting_832218	chr11_67403454_-	ncRNA_intronic
CAediting_832219	chr11_67403481_-	ncRNA_intronic
CAediting_832220	chr11_67403525_-	ncRNA_intronic
CAediting_832221	chr11_67403531_-	ncRNA_intronic
CAediting_832222	chr11_67403539_-	ncRNA_intronic
CAediting_832223	chr11_67403540_-	ncRNA_intronic
CAediting_832224	chr11_67403550_-	ncRNA_intronic
CAediting_832225	chr11_67403556_-	ncRNA_intronic
CAediting_832226	chr11_67403559_-	ncRNA_intronic
CAediting_832227	chr11_67403566_-	ncRNA_intronic
CAediting_832228	chr11_67403576_-	ncRNA_intronic
CAediting_832229	chr11_67403580_-	ncRNA_intronic
CAediting_832230	chr11_67403601_-	ncRNA_intronic
CAediting_832231	chr11_67403605_-	ncRNA_intronic
CAediting_832232	chr11_67403606_-	ncRNA_intronic
CAediting_832233	chr11_67403610_-	ncRNA_intronic
CAediting_832234	chr11_67403625_-	ncRNA_intronic
CAediting_832235	chr11_67403684_-	ncRNA_intronic
CAediting_832236	chr11_67403686_-	ncRNA_intronic
CAediting_832237	chr11_67413025_-	intronic
CAediting_832238	chr11_67413051_-	intronic
CAediting_832239	chr11_67413056_-	intronic
CAediting_832240	chr11_67413065_-	intronic
CAediting_832241	chr11_67413100_-	intronic
CAediting_832242	chr11_67413104_-	intronic
CAediting_832243	chr11_67413107_-	intronic
CAediting_832244	chr11_67413503_-	intronic
CAediting_832245	chr11_67413848_-	intronic
CAediting_832246	chr11_67413856_-	intronic
CAediting_832247	chr11_67413862_-	intronic
CAediting_832248	chr11_67413877_-	intronic
CAediting_832249	chr11_67413901_-	intronic
CAediting_832250	chr11_67413913_-	intronic
CAediting_832251	chr11_67413922_-	intronic
CAediting_832252	chr11_67413925_-	intronic
CAediting_832253	chr11_67413956_-	intronic
CAediting_832254	chr11_67413990_-	intronic
CAediting_832255	chr11_67413992_-	intronic
CAediting_832256	chr11_67414004_-	intronic
CAediting_832257	chr11_67414014_-	intronic
CAediting_832258	chr11_67414052_-	intronic
CAediting_832259	chr11_67414057_-	intronic
CAediting_832260	chr11_67414066_-	intronic
CAediting_832261	chr11_67414083_-	intronic
CAediting_832262	chr11_67414123_-	intronic
CAediting_832263	chr11_67414135_-	intronic
CAediting_832264	chr11_67414170_-	intronic
CAediting_832265	chr11_67414220_-	intronic
CAediting_832266	chr11_67414251_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_832157	chr11_67399988_-	SINE	Alu	AluSp
CAediting_832158	chr11_67400015_-	SINE	Alu	AluSp
CAediting_832159	chr11_67400037_-	SINE	Alu	AluSp
CAediting_832160	chr11_67400054_-	SINE	Alu	AluSp
CAediting_832161	chr11_67400106_-	SINE	Alu	AluSp
CAediting_832162	chr11_67400238_-	SINE	Alu	AluJr4
CAediting_832163	chr11_67400246_-	SINE	Alu	AluJr4
CAediting_832164	chr11_67402437_-	SINE	Alu	AluSz
CAediting_832165	chr11_67402438_-	SINE	Alu	AluSz
CAediting_832166	chr11_67402439_-	SINE	Alu	AluSz
CAediting_832167	chr11_67402442_-	SINE	Alu	AluSz
CAediting_832168	chr11_67402485_-	SINE	Alu	AluSz
CAediting_832169	chr11_67402497_-	SINE	Alu	AluSz
CAediting_832170	chr11_67402498_-	SINE	Alu	AluSz
CAediting_832171	chr11_67402505_-	SINE	Alu	AluSz
CAediting_832172	chr11_67402506_-	SINE	Alu	AluSz
CAediting_832173	chr11_67402514_-	SINE	Alu	AluSz
CAediting_832174	chr11_67402520_-	SINE	Alu	AluSz
CAediting_832175	chr11_67402524_-	SINE	Alu	AluSz
CAediting_832176	chr11_67402546_-	SINE	Alu	AluSz
CAediting_832177	chr11_67402579_-	SINE	Alu	AluSz
CAediting_832178	chr11_67402582_-	SINE	Alu	AluSz
CAediting_832179	chr11_67402584_-	SINE	Alu	AluSz
CAediting_832180	chr11_67402585_-	SINE	Alu	AluSz
CAediting_832181	chr11_67402586_-	SINE	Alu	AluSz
CAediting_832182	chr11_67402588_-	SINE	Alu	AluSz
CAediting_832183	chr11_67402597_-	SINE	Alu	AluSz
CAediting_832184	chr11_67402610_-	SINE	Alu	AluSz
CAediting_832185	chr11_67402621_-	SINE	Alu	AluSz
CAediting_832186	chr11_67402626_-	SINE	Alu	AluSz
CAediting_832187	chr11_67402627_-	SINE	Alu	AluSz
CAediting_832188	chr11_67402645_-	SINE	Alu	AluSz
CAediting_832189	chr11_67402658_-	SINE	Alu	AluSz
CAediting_832190	chr11_67402659_-	SINE	Alu	AluSz
CAediting_832191	chr11_67402681_-	SINE	Alu	AluSz
CAediting_832192	chr11_67402689_-	SINE	Alu	AluSz
CAediting_832193	chr11_67402703_-	SINE	Alu	AluSz
CAediting_832194	chr11_67402786_-	SINE	Alu	AluSx1
CAediting_832195	chr11_67402820_-	SINE	Alu	AluSx1
CAediting_832196	chr11_67402821_-	SINE	Alu	AluSx1
CAediting_832197	chr11_67402846_-	SINE	Alu	AluSx1
CAediting_832198	chr11_67402847_-	SINE	Alu	AluSx1
CAediting_832199	chr11_67402848_-	SINE	Alu	AluSx1
CAediting_832200	chr11_67402860_-	SINE	Alu	AluSx1
CAediting_832201	chr11_67402885_-	SINE	Alu	AluSx1
CAediting_832202	chr11_67402899_-	SINE	Alu	AluSx1
CAediting_832203	chr11_67402901_-	SINE	Alu	AluSx1
CAediting_832204	chr11_67402927_-	SINE	Alu	AluSx1
CAediting_832205	chr11_67402938_-	SINE	Alu	AluSx1
CAediting_832206	chr11_67402943_-	SINE	Alu	AluSx1
CAediting_832207	chr11_67402953_-	SINE	Alu	AluSx1
CAediting_832208	chr11_67402956_-	SINE	Alu	AluSx1
CAediting_832209	chr11_67402957_-	SINE	Alu	AluSx1
CAediting_832210	chr11_67402965_-	SINE	Alu	AluSx1
CAediting_832211	chr11_67402983_-	SINE	Alu	AluSx1
CAediting_832212	chr11_67403228_-	SINE	Alu	AluJb
CAediting_832213	chr11_67403230_-	SINE	Alu	AluJb
CAediting_832214	chr11_67403262_-	SINE	Alu	AluJb
CAediting_832215	chr11_67403268_-	SINE	Alu	AluJb
CAediting_832216	chr11_67403288_-	SINE	Alu	AluJb
CAediting_832217	chr11_67403453_-	SINE	Alu	AluSx
CAediting_832218	chr11_67403454_-	SINE	Alu	AluSx
CAediting_832219	chr11_67403481_-	SINE	Alu	AluSx
CAediting_832220	chr11_67403525_-	SINE	Alu	AluSx
CAediting_832221	chr11_67403531_-	SINE	Alu	AluSx
CAediting_832222	chr11_67403539_-	SINE	Alu	AluSx
CAediting_832223	chr11_67403540_-	SINE	Alu	AluSx
CAediting_832224	chr11_67403550_-	SINE	Alu	AluSx
CAediting_832225	chr11_67403556_-	SINE	Alu	AluSx
CAediting_832226	chr11_67403559_-	SINE	Alu	AluSx
CAediting_832227	chr11_67403566_-	SINE	Alu	AluSx
CAediting_832228	chr11_67403576_-	SINE	Alu	AluSx
CAediting_832229	chr11_67403580_-	SINE	Alu	AluSx
CAediting_832230	chr11_67403601_-	SINE	Alu	AluSx
CAediting_832231	chr11_67403605_-	SINE	Alu	AluSx
CAediting_832232	chr11_67403606_-	SINE	Alu	AluSx
CAediting_832233	chr11_67403610_-	SINE	Alu	AluSx
CAediting_832234	chr11_67403625_-	SINE	Alu	AluSx
CAediting_832235	chr11_67403684_-	SINE	Alu	AluSx
CAediting_832236	chr11_67403686_-	SINE	Alu	AluSx
CAediting_832244	chr11_67413503_-	SINE	MIR	MIRb
CAediting_832245	chr11_67413848_-	SINE	Alu	AluSc5
CAediting_832246	chr11_67413856_-	SINE	Alu	AluSc5
CAediting_832247	chr11_67413862_-	SINE	Alu	AluSc5
CAediting_832248	chr11_67413877_-	SINE	Alu	AluSc5
CAediting_832249	chr11_67413901_-	SINE	Alu	AluSc5
CAediting_832250	chr11_67413913_-	SINE	Alu	AluSc5
CAediting_832251	chr11_67413922_-	SINE	Alu	AluSc5
CAediting_832252	chr11_67413925_-	SINE	Alu	AluSc5
CAediting_832253	chr11_67413956_-	SINE	Alu	AluSc5
CAediting_832254	chr11_67413990_-	SINE	Alu	AluSx
CAediting_832255	chr11_67413992_-	SINE	Alu	AluSx
CAediting_832256	chr11_67414004_-	SINE	Alu	AluSx
CAediting_832257	chr11_67414014_-	SINE	Alu	AluSx
CAediting_832258	chr11_67414052_-	SINE	Alu	AluSx
CAediting_832259	chr11_67414057_-	SINE	Alu	AluSx
CAediting_832260	chr11_67414066_-	SINE	Alu	AluSx
CAediting_832261	chr11_67414083_-	SINE	Alu	AluSx
CAediting_832262	chr11_67414123_-	SINE	Alu	AluSx
CAediting_832263	chr11_67414135_-	SINE	Alu	AluSx
CAediting_832264	chr11_67414170_-	SINE	Alu	AluSx
CAediting_832265	chr11_67414220_-	SINE	Alu	AluSx
CAediting_832266	chr11_67414251_-	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for PPP1CA

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000172531.13.PPP1CA.

Correlation between RNA A-to-I editing and PSI for ENSG00000172531.13.PPP1CA.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PPP1CA

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for PPP1CA

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for PPP1CA

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_604450	chr7_133034877_-	ENSG00000172531.13	ENST00000312989	hsa-miR-3654	67398367	67398373	7mer-m8	67398366	67398382	147	-20.35
CAediting_580943	chr7_100356700_+	ENSG00000172531.13	ENST00000312989	hsa-miR-6840-3p	67398227	67398233	7mer-m8	67398226	67398248	150	-21.59

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PPP1CA

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for PPP1CA

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for PPP1CA

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for PPP1CA

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for PPP1CA

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for PPP1CA

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene