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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: PPIA (CAeditome ID:5478)

Gene summary for PPIA

check button Gene summary
Gene informationGene symbol

PPIA

Gene ID

5478

Gene namepeptidylprolyl isomerase A
SynonymsCYPA|CYPH|HEL-S-69p
Cytomap

7p13

Type of geneprotein-coding
Descriptionpeptidyl-prolyl cis-trans isomerase APPIase AT cell cyclophilincyclosporin A-binding proteinepididymis secretory sperm binding protein Li 69ppeptidylprolyl isomerase A (cyclophilin A)rotamase A
Modification date20210518
UniProtAcc

P62937

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
PPIA

GO:0003755

Peptidyl-prolyl cis-trans isomerase A

14993672

PPIA

GO:0003755

Peptidyl-prolyl cis-trans isomerase A

20676357

PPIA

GO:0016018

Peptidyl-prolyl cis-trans isomerase A

12218175

PPIA

GO:0016018

Peptidyl-prolyl cis-trans isomerase A

12357034

PPIA

GO:0016018

Peptidyl-prolyl cis-trans isomerase A

20676357

PPIA

GO:1904399

Peptidyl-prolyl cis-trans isomerase A

11943775

PPIA

GO:0000187

Peptidyl-prolyl cis-trans isomerase A

15130913

PPIA

GO:0000413

Peptidyl-prolyl cis-trans isomerase A

14993672

PPIA

GO:0000413

Peptidyl-prolyl cis-trans isomerase A

20676357

PPIA

GO:0001933

Peptidyl-prolyl cis-trans isomerase A

26095851

PPIA

GO:0001934

Peptidyl-prolyl cis-trans isomerase A

11943775

PPIA

GO:0006469

Peptidyl-prolyl cis-trans isomerase A

26095851

PPIA

GO:0006915

Peptidyl-prolyl cis-trans isomerase A

15130913

PPIA

GO:0030593

Peptidyl-prolyl cis-trans isomerase A

11943775

PPIA

GO:0032148

Peptidyl-prolyl cis-trans isomerase A

23180369

PPIA

GO:0034599

Peptidyl-prolyl cis-trans isomerase A

16527992

PPIA

GO:0042118

Peptidyl-prolyl cis-trans isomerase A

15130913

PPIA

GO:0051092

Peptidyl-prolyl cis-trans isomerase A

15130913

PPIA

GO:0051092

Peptidyl-prolyl cis-trans isomerase A

23180369

PPIA

GO:0060352

Peptidyl-prolyl cis-trans isomerase A

15130913

PPIA

GO:0005576

Peptidyl-prolyl cis-trans isomerase A

16527992

PPIA

GO:0005634

Peptidyl-prolyl cis-trans isomerase A

25678563

PPIA

GO:0005737

Peptidyl-prolyl cis-trans isomerase A

26095851

PPIA

GO:0032991

Peptidyl-prolyl cis-trans isomerase A

12218175


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RNA A-to-I events for PPIA

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000196262.12
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_542264(44798299, +), CAediting_542265(44798355, +), CAediting_542266(44798366, +), CAediting_542267(44798392, +), CAediting_542268(44798402, +), CAediting_542269(44798407, +), CAediting_542270(44798425, +), CAediting_542271(44798454, +), CAediting_542272(44800223, +), CAediting_542273(44800228, +), CAediting_542274(44800274, +), CAediting_542275(44800332, +), CAediting_542276(44800369, +), CAediting_542277(44800447, +), CAediting_542278(44800459, +), CAediting_542279(44800473, +), CAediting_542280(44800526, +), CAediting_542281(44800584, +), CAediting_542282(44800652, +), CAediting_542283(44800837, +), CAediting_542284(44800898, +), CAediting_542285(44801788, +), CAediting_542286(44801789, +), CAediting_542287(44801809, +), CAediting_542288(44801828, +), CAediting_542289(44801836, +), CAediting_542290(44801841, +), CAediting_542291(44801845, +), CAediting_542292(44801848, +), CAediting_542293(44801858, +), CAediting_542294(44801870, +), CAediting_542295(44801885, +), CAediting_542296(44801886, +), CAediting_542297(44801888, +), CAediting_542298(44801894, +), CAediting_542299(44801910, +), CAediting_542300(44801911, +), CAediting_542301(44801912, +), CAediting_542302(44801913, +), CAediting_542303(44801914, +), CAediting_542304(44801916, +), CAediting_542305(44801920, +), CAediting_542306(44801950, +), CAediting_542307(44801961, +), CAediting_542308(44801990, +), CAediting_542309(44802199, +), CAediting_542310(44802223, +), CAediting_542311(44802248, +), CAediting_542312(44802253, +), CAediting_542313(44802258, +), CAediting_542314(44802266, +), CAediting_542315(44802278, +), CAediting_542316(44802287, +), CAediting_542317(44802288, +), CAediting_542318(44802301, +), CAediting_542319(44802315, +), CAediting_542320(44802329, +), CAediting_542321(44802332, +), CAediting_542322(44802334, +), CAediting_542323(44802349, +), CAediting_542324(44802370, +), CAediting_542325(44802371, +), CAediting_542326(44802378, +), CAediting_542327(44802383, +), CAediting_542328(44802409, +), CAediting_542329(44802423, +), CAediting_542330(44802500, +), CAediting_542331(44815754, +), CAediting_542332(44818914, +), CAediting_542333(44821590, +), CAediting_542334(44821611, +), CAediting_542335(44821654, +),

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RNA editing positional annotations for PPIA using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_542264chr7_44798299_+ncRNA_exonic
CAediting_542265chr7_44798355_+ncRNA_exonic
CAediting_542266chr7_44798366_+ncRNA_exonic
CAediting_542267chr7_44798392_+ncRNA_exonic
CAediting_542268chr7_44798402_+ncRNA_exonic
CAediting_542269chr7_44798407_+ncRNA_exonic
CAediting_542270chr7_44798425_+ncRNA_exonic
CAediting_542271chr7_44798454_+ncRNA_exonic
CAediting_542272chr7_44800223_+ncRNA_intronic
CAediting_542273chr7_44800228_+ncRNA_intronic
CAediting_542274chr7_44800274_+ncRNA_intronic
CAediting_542275chr7_44800332_+ncRNA_intronic
CAediting_542276chr7_44800369_+ncRNA_intronic
CAediting_542277chr7_44800447_+ncRNA_exonic
CAediting_542278chr7_44800459_+ncRNA_exonic
CAediting_542279chr7_44800473_+ncRNA_exonic
CAediting_542280chr7_44800526_+ncRNA_exonic
CAediting_542281chr7_44800584_+ncRNA_intronic
CAediting_542282chr7_44800652_+ncRNA_intronic
CAediting_542283chr7_44800837_+ncRNA_intronic
CAediting_542284chr7_44800898_+ncRNA_intronic
CAediting_542285chr7_44801788_+UTR3
CAediting_542286chr7_44801789_+UTR3
CAediting_542287chr7_44801809_+UTR3
CAediting_542288chr7_44801828_+UTR3
CAediting_542289chr7_44801836_+UTR3
CAediting_542290chr7_44801841_+UTR3
CAediting_542291chr7_44801845_+UTR3
CAediting_542292chr7_44801848_+UTR3
CAediting_542293chr7_44801858_+UTR3
CAediting_542294chr7_44801870_+UTR3
CAediting_542295chr7_44801885_+UTR3
CAediting_542296chr7_44801886_+UTR3
CAediting_542297chr7_44801888_+UTR3
CAediting_542298chr7_44801894_+UTR3
CAediting_542299chr7_44801910_+UTR3
CAediting_542300chr7_44801911_+UTR3
CAediting_542301chr7_44801912_+UTR3
CAediting_542302chr7_44801913_+UTR3
CAediting_542303chr7_44801914_+UTR3
CAediting_542304chr7_44801916_+UTR3
CAediting_542305chr7_44801920_+UTR3
CAediting_542306chr7_44801950_+UTR3
CAediting_542307chr7_44801961_+UTR3
CAediting_542308chr7_44801990_+UTR3
CAediting_542309chr7_44802199_+UTR3
CAediting_542310chr7_44802223_+UTR3
CAediting_542311chr7_44802248_+UTR3
CAediting_542312chr7_44802253_+UTR3
CAediting_542313chr7_44802258_+UTR3
CAediting_542314chr7_44802266_+UTR3
CAediting_542315chr7_44802278_+UTR3
CAediting_542316chr7_44802287_+UTR3
CAediting_542317chr7_44802288_+UTR3
CAediting_542318chr7_44802301_+UTR3
CAediting_542319chr7_44802315_+UTR3
CAediting_542320chr7_44802329_+UTR3
CAediting_542321chr7_44802332_+UTR3
CAediting_542322chr7_44802334_+UTR3
CAediting_542323chr7_44802349_+UTR3
CAediting_542324chr7_44802370_+UTR3
CAediting_542325chr7_44802371_+UTR3
CAediting_542326chr7_44802378_+UTR3
CAediting_542327chr7_44802383_+UTR3
CAediting_542328chr7_44802409_+UTR3
CAediting_542329chr7_44802423_+UTR3
CAediting_542330chr7_44802500_+UTR3
CAediting_542331chr7_44815754_+intronic
CAediting_542332chr7_44818914_+intronic
CAediting_542333chr7_44821590_+intronic
CAediting_542334chr7_44821611_+intronic
CAediting_542335chr7_44821654_+intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_542264chr7_44798299_+SINEAluAluSc5
CAediting_542265chr7_44798355_+SINEAluAluSc5
CAediting_542266chr7_44798366_+SINEAluAluSc5
CAediting_542267chr7_44798392_+SINEAluAluSc5
CAediting_542268chr7_44798402_+SINEAluAluSc5
CAediting_542269chr7_44798407_+SINEAluAluSc5
CAediting_542270chr7_44798425_+SINEAluAluSc5
CAediting_542271chr7_44798454_+SINEAluAluSc5
CAediting_542272chr7_44800223_+SINEAluAluSx
CAediting_542273chr7_44800228_+SINEAluAluSx
CAediting_542274chr7_44800274_+SINEAluAluSx
CAediting_542275chr7_44800332_+SINEAluAluSx
CAediting_542276chr7_44800369_+SINEAluAluSx
CAediting_542277chr7_44800447_+SINEAluAluSz
CAediting_542278chr7_44800459_+SINEAluAluSz
CAediting_542279chr7_44800473_+SINEAluAluSz
CAediting_542280chr7_44800526_+SINEAluAluSz
CAediting_542281chr7_44800584_+SINEAluAluSz
CAediting_542282chr7_44800652_+SINEAluAluSz
CAediting_542283chr7_44800837_+SINEAluAluY
CAediting_542284chr7_44800898_+SINEAluAluY
CAediting_542287chr7_44801809_+SINEAluAluJr
CAediting_542288chr7_44801828_+SINEAluAluJr
CAediting_542289chr7_44801836_+SINEAluAluJr
CAediting_542290chr7_44801841_+SINEAluAluJr
CAediting_542291chr7_44801845_+SINEAluAluJr
CAediting_542292chr7_44801848_+SINEAluAluJr
CAediting_542293chr7_44801858_+SINEAluAluJr
CAediting_542294chr7_44801870_+SINEAluAluJr
CAediting_542295chr7_44801885_+SINEAluAluJr
CAediting_542296chr7_44801886_+SINEAluAluJr
CAediting_542297chr7_44801888_+SINEAluAluJr
CAediting_542298chr7_44801894_+SINEAluAluJr
CAediting_542299chr7_44801910_+SINEAluAluJr
CAediting_542300chr7_44801911_+SINEAluAluJr
CAediting_542301chr7_44801912_+SINEAluAluJr
CAediting_542302chr7_44801913_+SINEAluAluJr
CAediting_542303chr7_44801914_+SINEAluAluJr
CAediting_542304chr7_44801916_+SINEAluAluJr
CAediting_542305chr7_44801920_+SINEAluAluJr
CAediting_542306chr7_44801950_+SINEAluAluJr
CAediting_542307chr7_44801961_+SINEAluAluJr
CAediting_542308chr7_44801990_+SINEAluAluJr
CAediting_542309chr7_44802199_+SINEAluAluSx
CAediting_542310chr7_44802223_+SINEAluAluSx
CAediting_542311chr7_44802248_+SINEAluAluSx
CAediting_542312chr7_44802253_+SINEAluAluSx
CAediting_542313chr7_44802258_+SINEAluAluSx
CAediting_542314chr7_44802266_+SINEAluAluSx
CAediting_542315chr7_44802278_+SINEAluAluSx
CAediting_542316chr7_44802287_+SINEAluAluSx
CAediting_542317chr7_44802288_+SINEAluAluSx
CAediting_542318chr7_44802301_+SINEAluAluSx
CAediting_542319chr7_44802315_+SINEAluAluSx
CAediting_542320chr7_44802329_+SINEAluAluSx
CAediting_542321chr7_44802332_+SINEAluAluSx
CAediting_542322chr7_44802334_+SINEAluAluSx
CAediting_542323chr7_44802349_+SINEAluAluSx
CAediting_542324chr7_44802370_+SINEAluAluSx
CAediting_542325chr7_44802371_+SINEAluAluSx
CAediting_542326chr7_44802378_+SINEAluAluSx
CAediting_542327chr7_44802383_+SINEAluAluSx
CAediting_542328chr7_44802409_+SINEAluAluSx
CAediting_542329chr7_44802423_+SINEAluAluSx
CAediting_542331chr7_44815754_+SINEAluAluSp
CAediting_542332chr7_44818914_+SINEAluAluSq2
CAediting_542333chr7_44821590_+SINEAluAluJb
CAediting_542334chr7_44821611_+SINEAluAluJb
CAediting_542335chr7_44821654_+SINEAluAluJb

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RNA A-to-I editing events in the alternative splicing sites for PPIA

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000196262.12.PPIA.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000196262.12.PPIA.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PPIA

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for PPIA

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for PPIA

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_542279chr7_44800473_+ENSG00000196262.12ENST00000415933hsa-miR-453744800470448004778mer-1a4480045744800477154.00-26.68
CAediting_542292chr7_44801848_+ENSG00000196262.12ENST00000468812hsa-miR-390944801844448018507mer-m84480183444801851149.00-20.00
CAediting_542292chr7_44801848_+ENSG00000196262.12ENST00000468812hsa-miR-6780a-3p44801843448018497mer-m84480183044801850148.00-14.29
CAediting_542292chr7_44801848_+ENSG00000196262.12ENST00000468812hsa-miR-6852-3p44801844448018507mer-m84480183744801851152.00-23.55
CAediting_542298chr7_44801894_+ENSG00000196262.12ENST00000468812hsa-miR-3156-3p44801889448018957mer-m84480187644801896140.00-17.24
CAediting_542298chr7_44801894_+ENSG00000196262.12ENST00000468812hsa-miR-3156-3p44801889448018957mer-m84480187644801896140.00-17.24
CAediting_542298chr7_44801894_+ENSG00000196262.12ENST00000468812hsa-miR-430144801888448018958mer-1a4480187644801895141.00-15.44
CAediting_542298chr7_44801894_+ENSG00000196262.12ENST00000468812hsa-miR-4433a-5p44801890448018967mer-m84480187744801897140.00-20.78
CAediting_542301chr7_44801912_+ENSG00000196262.12ENST00000468812hsa-miR-684444801906448019138mer-1a4480189344801913140.00-11.27
CAediting_542306chr7_44801950_+ENSG00000196262.12ENST00000468812hsa-miR-3157-5p44801948448019547mer-m84480193444801955167.00-27.44
CAediting_542308chr7_44801990_+ENSG00000196262.12ENST00000468812hsa-miR-3155a44801983448019897mer-m84480196944801990149.00-22.90
CAediting_542308chr7_44801990_+ENSG00000196262.12ENST00000468812hsa-miR-3155b44801983448019897mer-m84480197244801990149.00-22.90
CAediting_542308chr7_44801990_+ENSG00000196262.12ENST00000468812hsa-miR-508-5p44801987448019937mer-m84480197644801994143.00-17.02
CAediting_542313chr7_44802258_+ENSG00000196262.12ENST00000468812hsa-miR-593-5p44802256448022627mer-m84480223844802263154.00-27.52
CAediting_542313chr7_44802258_+ENSG00000196262.12ENST00000468812hsa-miR-9851-3p44802256448022627mer-m84480223944802263150.00-20.60
CAediting_542318chr7_44802301_+ENSG00000196262.12ENST00000468812hsa-miR-6770-3p44802297448023037mer-m84480228344802304146.00-19.34
CAediting_542318chr7_44802301_+ENSG00000196262.12ENST00000468812hsa-miR-6770-3p44802297448023037mer-m84480228344802304146.00-19.34
CAediting_542318chr7_44802301_+ENSG00000196262.12ENST00000468812hsa-miR-6770-3p44802297448023037mer-m84480228344802304146.00-19.34
CAediting_542321chr7_44802332_+ENSG00000196262.12ENST00000468812hsa-miR-4704-5p44802327448023337mer-1a4480231244802333141.00-12.98
CAediting_542323chr7_44802349_+ENSG00000196262.12ENST00000468812hsa-miR-548ad-3p44802346448023527mer-m84480233344802353144.00-9.25
CAediting_542325chr7_44802371_+ENSG00000196262.12ENST00000468812hsa-miR-453844802367448023726mer4480235144802373141.00-25.52
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-428744802494448024996mer4480248244802500147.00-22.19
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-446944802493448024997mer-m84480247944802500150.00-22.02
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-4633-5p44802498448025047mer-m84480248644802505144.00-15.79
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-6778-3p44802495448025028mer-1a4480247944802502148.00-25.24
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-6836-3p44802496448025027mer-m84480248344802503149.00-20.63
CAediting_542288chr7_44801828_+ENSG00000196262.12ENST00000468812hsa-miR-499a-3p44801825448018328mer-1a4480181144801832159.00-17.32
CAediting_542288chr7_44801828_+ENSG00000196262.12ENST00000468812hsa-miR-499b-3p44801825448018328mer-1a4480181144801832151.00-12.26
CAediting_542289chr7_44801836_+ENSG00000196262.12ENST00000468812hsa-miR-4742-5p44801833448018408mer-1a4480181844801840153.00-21.25
CAediting_542293chr7_44801858_+ENSG00000196262.12ENST00000468812hsa-miR-361-3p44801854448018607mer-m84480183944801861171.00-32.39
CAediting_542293chr7_44801858_+ENSG00000196262.12ENST00000468812hsa-miR-4726-3p44801852448018587mer-m84480183844801859151.00-21.33
CAediting_542293chr7_44801858_+ENSG00000196262.12ENST00000468812hsa-miR-6798-3p44801856448018627mer-m84480184344801863140.00-17.14
CAediting_542304chr7_44801916_+ENSG00000196262.12ENST00000468812hsa-miR-153-5p44801909448019168mer-1a4480189644801916150.00-14.08
CAediting_542307chr7_44801961_+ENSG00000196262.12ENST00000468812hsa-miR-361-3p44801956448019627mer-m84480194144801963147.00-21.18
CAediting_542307chr7_44801961_+ENSG00000196262.12ENST00000468812hsa-miR-394344801958448019647mer-m84480194544801965162.00-29.22
CAediting_542309chr7_44802199_+ENSG00000196262.12ENST00000468812hsa-miR-1915-3p44802192448021998mer-1a4480218044802199143.00-15.91
CAediting_542309chr7_44802199_+ENSG00000196262.12ENST00000468812hsa-miR-324-5p44802196448022038mer-1a4480218444802203149.00-18.29
CAediting_542309chr7_44802199_+ENSG00000196262.12ENST00000468812hsa-miR-6764-5p44802192448021998mer-1a4480217844802199140.00-18.19
CAediting_542312chr7_44802253_+ENSG00000196262.12ENST00000468812hsa-miR-1255b-2-3p44802247448022537mer-m84480223344802254140.00-13.19
CAediting_542315chr7_44802278_+ENSG00000196262.12ENST00000468812hsa-miR-4691-3p44802275448022817mer-m84480225644802282153.00-28.33
CAediting_542317chr7_44802288_+ENSG00000196262.12ENST00000468812hsa-miR-430144802285448022917mer-m84480227344802292154.00-17.83
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-4661-5p44802309448023157mer-m84480229744802316145.00-14.64
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548ae-3p44802313448023197mer-m84480230044802320141.00-10.48
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548ae-3p44802313448023197mer-m84480230044802320141.00-10.48
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548ah-3p44802313448023197mer-m84480229844802320143.00-10.48
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548aj-3p44802313448023197mer-m84480230044802320141.00-8.37
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548aj-3p44802313448023197mer-m84480230044802320141.00-8.37
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548am-3p44802313448023197mer-m84480229844802320143.00-10.48
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548aq-3p44802313448023197mer-m84480229944802320141.00-10.48
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548j-3p44802313448023197mer-m84480230044802320141.00-10.48
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548x-3p44802313448023197mer-m84480230144802320141.00-8.37
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-548x-3p44802313448023197mer-m84480230144802320141.00-8.37
CAediting_542319chr7_44802315_+ENSG00000196262.12ENST00000468812hsa-miR-7844-5p44802311448023177mer-m84480229744802318160.00-18.30
CAediting_542324chr7_44802370_+ENSG00000196262.12ENST00000468812hsa-miR-432944802363448023708mer-1a4480235044802370147.00-14.90
CAediting_542324chr7_44802370_+ENSG00000196262.12ENST00000468812hsa-miR-5007-5p44802368448023747mer-m84480235244802375155.00-20.82
CAediting_542328chr7_44802409_+ENSG00000196262.12ENST00000468812hsa-miR-6771-5p44802403448024108mer-1a4480239144802410161.00-32.19
CAediting_542277chr7_44800447_+ENSG00000196262.12ENST00000415933hsa-miR-1247-3p44800442448004487mer-m84480042444800449147.00-24.05
CAediting_542277chr7_44800447_+ENSG00000196262.12ENST00000415933hsa-miR-6746-5p44800440448004467mer-m84480042444800447154.00-29.38
CAediting_542290chr7_44801841_+ENSG00000196262.12ENST00000468812hsa-miR-191344801839448018468mer-1a4480182544801846140.00-16.43
CAediting_542290chr7_44801841_+ENSG00000196262.12ENST00000468812hsa-miR-4726-3p44801835448018417mer-m84480182144801842140.00-14.16
CAediting_542296chr7_44801886_+ENSG00000196262.12ENST00000468812hsa-miR-6882-3p44801881448018877mer-1a4480186144801887145.00-23.13
CAediting_542300chr7_44801911_+ENSG00000196262.12ENST00000468812hsa-miR-57844801906448019138mer-1a4480189344801913141.00-10.94

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_542288chr7_44801828_+ENSG00000196262.12ENST00000468812hsa-miR-10399-5p44801823448018297mer-m84480181044801830153-12.81
CAediting_542285chr7_44801788_+ENSG00000196262.12ENST00000468812hsa-miR-1250-3p44801785448017917mer-m84480177244801792144-15.68
CAediting_542286chr7_44801789_+ENSG00000196262.12ENST00000468812hsa-miR-1250-3p44801785448017917mer-m84480177244801792144-15.68
CAediting_542323chr7_44802349_+ENSG00000196262.12ENST00000468812hsa-miR-127244802343448023497mer-m84480232444802350149-14.68
CAediting_542285chr7_44801788_+ENSG00000196262.12ENST00000468812hsa-miR-153-5p44801786448017916mer4480177344801792140-10.51
CAediting_542286chr7_44801789_+ENSG00000196262.12ENST00000468812hsa-miR-153-5p44801786448017916mer4480177344801792140-10.51
CAediting_542308chr7_44801990_+ENSG00000196262.12ENST00000468812hsa-miR-3059-3p44801986448019927mer-m84480197244801993145-13.75
CAediting_542328chr7_44802409_+ENSG00000196262.12ENST00000468812hsa-miR-30b-3p44802402448024098mer-1a4480238844802409147-15.45
CAediting_542306chr7_44801950_+ENSG00000196262.12ENST00000468812hsa-miR-3117-3p44801943448019497mer-m84480192744801950150-19.01
CAediting_542310chr7_44802223_+ENSG00000196262.12ENST00000468812hsa-miR-317444802219448022246mer4480220544802225146-25.35
CAediting_542288chr7_44801828_+ENSG00000196262.12ENST00000468812hsa-miR-323a-3p44801825448018328mer-1a4480181044801832153-15.31
CAediting_542312chr7_44802253_+ENSG00000196262.12ENST00000468812hsa-miR-34b-3p44802248448022547mer-m84480223244802255148-11.23
CAediting_542311chr7_44802248_+ENSG00000196262.12ENST00000468812hsa-miR-3614-5p44802246448022527mer-1a4480222944802252151-21.52
CAediting_542299chr7_44801910_+ENSG00000196262.12ENST00000468812hsa-miR-367444801903448019108mer-1a4480188844801910141-9.74
CAediting_542329chr7_44802423_+ENSG00000196262.12ENST00000468812hsa-miR-368644802420448024267mer-m84480240644802427140-11.98
CAediting_542328chr7_44802409_+ENSG00000196262.12ENST00000468812hsa-miR-3689a-3p44802402448024098mer-1a4480238844802409141-16.26
CAediting_542328chr7_44802409_+ENSG00000196262.12ENST00000468812hsa-miR-3689b-3p44802402448024098mer-1a4480238844802409141-16.45
CAediting_542328chr7_44802409_+ENSG00000196262.12ENST00000468812hsa-miR-3689c44802402448024098mer-1a4480238844802409141-16.45
CAediting_542289chr7_44801836_+ENSG00000196262.12ENST00000468812hsa-miR-374c-5p44801829448018357mer-m84480181544801836144-10.48
CAediting_542314chr7_44802266_+ENSG00000196262.12ENST00000468812hsa-miR-397544802265448022706mer4480225044802271140-18.82
CAediting_542314chr7_44802266_+ENSG00000196262.12ENST00000468812hsa-miR-447844802263448022697mer-m84480225444802270145-19.26
CAediting_542314chr7_44802266_+ENSG00000196262.12ENST00000468812hsa-miR-4649-3p44802260448022667mer-m84480224544802267143-15.87
CAediting_542323chr7_44802349_+ENSG00000196262.12ENST00000468812hsa-miR-469844802347448023548mer-1a4480233544802354153-21.56
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-4755-5p44802494448024996mer4480247944802500144-17.06
CAediting_542314chr7_44802266_+ENSG00000196262.12ENST00000468812hsa-miR-485-5p44802264448022707mer-m84480225044802271153-18.12
CAediting_542291chr7_44801845_+ENSG00000196262.12ENST00000468812hsa-miR-5001-3p44801840448018478mer-1a4480182644801847147-18.72
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-516a-3p44802496448025027mer-1a4480248544802502143-19.21
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-516a-3p44802496448025027mer-1a4480248544802502143-19.21
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-516b-3p44802496448025027mer-1a4480248544802502143-19.21
CAediting_542330chr7_44802500_+ENSG00000196262.12ENST00000468812hsa-miR-516b-3p44802496448025027mer-1a4480248544802502143-19.21
CAediting_542315chr7_44802278_+ENSG00000196262.12ENST00000468812hsa-miR-569044802275448022817mer-m84480226244802282145-17.72
CAediting_542308chr7_44801990_+ENSG00000196262.12ENST00000468812hsa-miR-64544801984448019918mer-1a4480197144801991148-16.14
CAediting_542295chr7_44801885_+ENSG00000196262.12ENST00000468812hsa-miR-6501-5p44801881448018877mer-1a4480186644801887144-26.14
CAediting_542296chr7_44801886_+ENSG00000196262.12ENST00000468812hsa-miR-6501-5p44801881448018877mer-1a4480186644801887144-26.14
CAediting_542288chr7_44801828_+ENSG00000196262.12ENST00000468812hsa-miR-6504-3p44801823448018297mer-m84480180844801830152-20.09
CAediting_542289chr7_44801836_+ENSG00000196262.12ENST00000468812hsa-miR-655-3p44801829448018357mer-m84480181544801836148-6.02
CAediting_542291chr7_44801845_+ENSG00000196262.12ENST00000468812hsa-miR-6738-3p44801841448018477mer-m84480182444801848147-16.89
CAediting_542292chr7_44801848_+ENSG00000196262.12ENST00000468812hsa-miR-6738-3p44801841448018477mer-m84480182444801848147-16.89
CAediting_542292chr7_44801848_+ENSG00000196262.12ENST00000468812hsa-miR-6740-3p44801844448018507mer-m84480183144801851148-14.83
CAediting_542328chr7_44802409_+ENSG00000196262.12ENST00000468812hsa-miR-6740-5p44802405448024117mer-m84480238944802412154-24.35
CAediting_542328chr7_44802409_+ENSG00000196262.12ENST00000468812hsa-miR-6779-5p44802402448024098mer-1a4480239044802409142-21.01
CAediting_542287chr7_44801809_+ENSG00000196262.12ENST00000468812hsa-miR-6872-3p44801805448018117mer-m84480179144801812148-20.35
CAediting_542314chr7_44802266_+ENSG00000196262.12ENST00000468812hsa-miR-6884-5p44802264448022707mer-m84480225044802271150-18.96
CAediting_542314chr7_44802266_+ENSG00000196262.12ENST00000468812hsa-miR-7160-5p44802261448022677mer-m84480224844802268146-15.14
CAediting_542327chr7_44802383_+ENSG00000196262.12ENST00000468812hsa-miR-7162-3p44802377448023837mer-m84480236744802384145-14.03
CAediting_542295chr7_44801885_+ENSG00000196262.12ENST00000468812hsa-miR-744-3p44801881448018877mer-m84480186444801888146-10.6
CAediting_542296chr7_44801886_+ENSG00000196262.12ENST00000468812hsa-miR-744-3p44801881448018877mer-m84480186444801888146-10.6
CAediting_542297chr7_44801888_+ENSG00000196262.12ENST00000468812hsa-miR-744-3p44801881448018877mer-m84480186444801888146-10.6
CAediting_542293chr7_44801858_+ENSG00000196262.12ENST00000468812hsa-miR-7848-3p44801856448018627mer-m84480184044801863152-26.4
CAediting_542328chr7_44802409_+ENSG00000196262.12ENST00000468812hsa-miR-887-5p44802403448024108mer-1a4480238944802410150-16.93
CAediting_542303chr7_44801914_+ENSG00000196262.12ENST00000468812hsa-miR-94444801912448019198mer-1a4480189744801919143-5.94
CAediting_542304chr7_44801916_+ENSG00000196262.12ENST00000468812hsa-miR-94444801912448019198mer-1a4480189744801919143-5.94
CAediting_542277chr7_44800447_+ENSG00000196262.12ENST00000415933hsa-miR-30c-1-3p44800440448004467mer-m84480042644800447140-19.59
CAediting_542277chr7_44800447_+ENSG00000196262.12ENST00000415933hsa-miR-30c-2-3p44800440448004467mer-m84480042544800447142-18.86
CAediting_542279chr7_44800473_+ENSG00000196262.12ENST00000415933hsa-miR-3160-3p44800470448004778mer-1a4480045644800477150-18.15
CAediting_542279chr7_44800473_+ENSG00000196262.12ENST00000415933hsa-miR-3160-3p44800470448004778mer-1a4480045644800477150-18.15
CAediting_542278chr7_44800459_+ENSG00000196262.12ENST00000415933hsa-miR-324-3p44800456448004627mer-m84480044144800463144-22.17
CAediting_542277chr7_44800447_+ENSG00000196262.12ENST00000415933hsa-miR-4714-3p44800446448004516mer4480043144800452144-25.28
CAediting_542277chr7_44800447_+ENSG00000196262.12ENST00000415933hsa-miR-490-3p44800444448004507mer-m84480043044800451148-18.92
CAediting_542277chr7_44800447_+ENSG00000196262.12ENST00000415933hsa-miR-6780a-5p44800441448004466mer4480042744800447146-21.67

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_688081chr9_63819627_+ENSG00000196262.12ENST00000451562hsa-miR-4477b44799983447999897mer-m84479996944799990140-11.89
CAediting_86358chr1_109598906_+ENSG00000196262.12ENST00000489459hsa-miR-197-5p44801484448014907mer-m84480146844801491153-24.57
CAediting_86358chr1_109598906_+ENSG00000196262.12ENST00000355968hsa-miR-197-5p44801484448014907mer-m84480146844801491153-24.57
CAediting_1229413chr17_67471544_+ENSG00000196262.12ENST00000468812hsa-miR-548aa44802766448027727mer-m84480275144802773146-12.01
CAediting_1351755chr19_40282625_-ENSG00000196262.12ENST00000468812hsa-miR-64144802040448020467mer-1a4480202144802046148-25.38
CAediting_86358chr1_109598906_+ENSG00000196262.12ENST00000468812hsa-miR-197-5p44801484448014907mer-m84480146844801491153-24.57
CAediting_228905chr2_188297554_+ENSG00000196262.12ENST00000468812hsa-miR-561-3p44802368448023747mer-m84480235244802375161-16.51
CAediting_86358chr1_109598906_+ENSG00000196262.12ENST00000479021hsa-miR-197-5p44823279448232857mer-m84482326344823286155-27.84
CAediting_580943chr7_100356700_+ENSG00000196262.12ENST00000415933hsa-miR-6840-3p44800489448004957mer-m84480047444800496147-24.38
CAediting_86358chr1_109598906_+ENSG00000196262.12ENST00000415933hsa-miR-197-5p44801484448014907mer-m84480146844801491153-24.57
CAediting_468389chr6_31355314_-ENSG00000196262.12ENST00000415933hsa-miR-6891-5p44800484448004907mer-m84480047144800491147-22.62

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_846604chr11_93733708_-ENSG00000196262.12ENST00000468812hsa-miR-1304-3p44802634448026407mer-m84480262044802641151-20.59
CAediting_846604chr11_93733708_-ENSG00000196262.12ENST00000468812hsa-miR-1304-3p44801991448019966mer4480197644801997143-19.51

check button Differentially expressed gene-miRNA network
boxplot

Top

The effects of the RNA editing to the stability of the RNA structures for PPIA

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000415933.4nonsense_mediated_decaySoverviewSoverview
ENST00000468812.4protein_codingSoverviewSoverview
ENST00000494484.1retained_intronSoverviewSoverview
ENST00000480603.1processed_transcriptSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_542277ENST00000415933.4chr7_44800447_+-274.10-268.10-277.50
CAediting_542278ENST00000415933.4chr7_44800459_+-267.40-268.10-277.50
CAediting_542279ENST00000415933.4chr7_44800473_+-272.20-268.10-277.50
CAediting_542280ENST00000415933.4chr7_44800526_+-268.10-268.10-277.50
CAediting_542285ENST00000468812.4chr7_44801788_+-784.10-784.00-790.50
CAediting_542286ENST00000468812.4chr7_44801789_+-784.10-784.00-790.50
CAediting_542287ENST00000468812.4chr7_44801809_+-789.10-784.00-790.50
CAediting_542288ENST00000468812.4chr7_44801828_+-784.10-784.00-790.50
CAediting_542289ENST00000468812.4chr7_44801836_+-786.60-784.00-790.50
CAediting_542290ENST00000468812.4chr7_44801841_+-783.90-784.00-790.50
CAediting_542291ENST00000468812.4chr7_44801845_+-784.50-784.00-790.50
CAediting_542292ENST00000468812.4chr7_44801848_+-786.30-784.00-790.50
CAediting_542293ENST00000468812.4chr7_44801858_+-783.10-784.00-790.50
CAediting_542294ENST00000468812.4chr7_44801870_+-787.40-784.00-790.50
CAediting_542295ENST00000468812.4chr7_44801885_+-783.70-784.00-790.50
CAediting_542296ENST00000468812.4chr7_44801886_+-783.70-784.00-790.50
CAediting_542297ENST00000468812.4chr7_44801888_+-784.30-784.00-790.50
CAediting_542298ENST00000468812.4chr7_44801894_+-783.00-784.00-790.50
CAediting_542299ENST00000468812.4chr7_44801910_+-783.40-784.00-790.50
CAediting_542300ENST00000468812.4chr7_44801911_+-784.10-784.00-790.50
CAediting_542301ENST00000468812.4chr7_44801912_+-784.10-784.00-790.50
CAediting_542302ENST00000468812.4chr7_44801913_+-784.10-784.00-790.50
CAediting_542303ENST00000468812.4chr7_44801914_+-784.00-784.00-790.50
CAediting_542304ENST00000468812.4chr7_44801916_+-784.00-784.00-790.50
CAediting_542305ENST00000468812.4chr7_44801920_+-783.70-784.00-790.50
CAediting_542306ENST00000468812.4chr7_44801950_+-782.70-784.00-790.50
CAediting_542307ENST00000468812.4chr7_44801961_+-783.10-784.00-790.50
CAediting_542308ENST00000468812.4chr7_44801990_+-782.70-784.00-790.50
CAediting_542309ENST00000468812.4chr7_44802199_+-785.30-784.00-790.50
CAediting_542310ENST00000468812.4chr7_44802223_+-783.60-784.00-790.50
CAediting_542311ENST00000468812.4chr7_44802248_+-783.70-784.00-790.50
CAediting_542312ENST00000468812.4chr7_44802253_+-783.50-784.00-790.50
CAediting_542313ENST00000468812.4chr7_44802258_+-784.00-784.00-790.50
CAediting_542314ENST00000468812.4chr7_44802266_+-783.30-784.00-790.50
CAediting_542315ENST00000468812.4chr7_44802278_+-783.40-784.00-790.50
CAediting_542316ENST00000468812.4chr7_44802287_+-784.00-784.00-790.50
CAediting_542317ENST00000468812.4chr7_44802288_+-784.00-784.00-790.50
CAediting_542318ENST00000468812.4chr7_44802301_+-783.60-784.00-790.50
CAediting_542319ENST00000468812.4chr7_44802315_+-784.00-784.00-790.50
CAediting_542320ENST00000468812.4chr7_44802329_+-784.00-784.00-790.50
CAediting_542321ENST00000468812.4chr7_44802332_+-783.70-784.00-790.50
CAediting_542322ENST00000468812.4chr7_44802334_+-784.00-784.00-790.50
CAediting_542323ENST00000468812.4chr7_44802349_+-784.30-784.00-790.50
CAediting_542324ENST00000468812.4chr7_44802370_+-787.40-784.00-790.50
CAediting_542325ENST00000468812.4chr7_44802371_+-784.30-784.00-790.50
CAediting_542326ENST00000468812.4chr7_44802378_+-786.50-784.00-790.50
CAediting_542327ENST00000468812.4chr7_44802383_+-783.30-784.00-790.50
CAediting_542328ENST00000468812.4chr7_44802409_+-784.00-784.00-790.50
CAediting_542329ENST00000468812.4chr7_44802423_+-784.00-784.00-790.50
CAediting_542330ENST00000468812.4chr7_44802500_+-783.70-784.00-790.50
CAediting_542264ENST00000494484.1chr7_44798299_+-626.70-626.70-630.10
CAediting_542265ENST00000494484.1chr7_44798355_+-626.50-626.70-630.10
CAediting_542266ENST00000494484.1chr7_44798366_+-628.20-626.70-630.10
CAediting_542267ENST00000494484.1chr7_44798392_+-626.70-626.70-630.10
CAediting_542268ENST00000494484.1chr7_44798402_+-627.10-626.70-630.10
CAediting_542269ENST00000494484.1chr7_44798407_+-626.80-626.70-630.10
CAediting_542270ENST00000494484.1chr7_44798425_+-630.90-626.70-630.10
CAediting_542271ENST00000494484.1chr7_44798454_+-626.00-626.70-630.10
CAediting_542277ENST00000480603.1chr7_44800447_+-258.60-254.80-262.00
CAediting_542278ENST00000480603.1chr7_44800459_+-254.10-254.80-262.00
CAediting_542279ENST00000480603.1chr7_44800473_+-258.90-254.80-262.00
CAediting_542280ENST00000480603.1chr7_44800526_+-254.80-254.80-262.00

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Relation with ADAR for PPIA

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LGGCAediting_542286chr7_44801789_+0.0001439983877081470.334840762672884....
BRCACAediting_542286chr7_44801789_+3.11646456770107e-250.406758234336532....
LIHCCAediting_542286chr7_44801789_+0.0004621370434868920.291082970527635....
LUADCAediting_542286chr7_44801789_+6.61371430093433e-110.379901046112257....
LUSCCAediting_542286chr7_44801789_+0.0001908539138614510.274626600640035....
HNSCCAediting_542286chr7_44801789_+0.01640829339820230.231545873987233....
STADCAediting_542286chr7_44801789_+8.17101027054429e-050.383576461222303....
PAADCAediting_542286chr7_44801789_+0.005867884227856060.338156481486376....
PCPGCAediting_542286chr7_44801789_+0.0356185528477360.236810357233571....
TGCTCAediting_542286chr7_44801789_+6.26497252521508e-090.627194632957249....
BLCACAediting_542305chr7_44801920_+8.20630425781178e-100.350608342505593....
LGGCAediting_542305chr7_44801920_+1.03741950661615e-110.294047351933375....
BRCACAediting_542305chr7_44801920_+6.19060102739655e-960.586742566943735....
LIHCCAediting_542305chr7_44801920_+4.17538133190763e-090.328486089188731....
CESCCAediting_542305chr7_44801920_+5.48997315858752e-170.496793340020593....
LUADCAediting_542305chr7_44801920_+3.23942805951097e-250.449643724117328....
COADCAediting_542305chr7_44801920_+5.34837747822701e-110.343658581987915....
LUSCCAediting_542305chr7_44801920_+1.80504381747681e-310.517211525265622..0.01089783595796320.12127048440432
GBMCAediting_542305chr7_44801920_+2.04849127399879e-110.495427827239768....
PRADCAediting_542305chr7_44801920_+3.2346789011279e-160.419418680589088....
HNSCCAediting_542305chr7_44801920_+1.35784860815507e-220.440044590056235....
STADCAediting_542305chr7_44801920_+2.24002097180826e-160.428283603980412....
THCACAediting_542305chr7_44801920_+0.0132634902621920.135600144148283....
KIRCCAediting_542305chr7_44801920_+1.11837673285031e-060.22078458636798....
UCECCAediting_542305chr7_44801920_+6.11810699272333e-140.401474915852019..0.02721746554753560.122888145011121
KIRPCAediting_542305chr7_44801920_+0.0004747087051210470.252416265751987....
ESCACAediting_542305chr7_44801920_+2.11702525583412e-080.432546795241134....
LAMLCAediting_542305chr7_44801920_+7.06905305650142e-050.426860861809398....
OVCAediting_542305chr7_44801920_+7.09324099101883e-090.308303371262724....
PAADCAediting_542305chr7_44801920_+0.002539240541432190.24237947433248....
PCPGCAediting_542305chr7_44801920_+5.36115892967747e-080.431593168989808....
SKCMCAediting_542305chr7_44801920_+4.30132323177638e-260.491083169804835....
MESOCAediting_542305chr7_44801920_+0.0004790541656787460.403816542337583....
READCAediting_542305chr7_44801920_+0.0003784555125295740.3130539712241....
SARCCAediting_542305chr7_44801920_+1.43431246551326e-100.448027791626126....
TGCTCAediting_542305chr7_44801920_+5.6202985450519e-190.684030116727634....
THYMCAediting_542305chr7_44801920_+1.30803656042224e-100.633416057975088....
BLCACAediting_542308chr7_44801990_+0.006102901043031250.240229394995456....
LGGCAediting_542308chr7_44801990_+1.2924348023384e-090.363072491729825....
BRCACAediting_542308chr7_44801990_+3.94286605167073e-230.380179771684893....
LIHCCAediting_542308chr7_44801990_+4.78881459707624e-080.357824173834689....
CESCCAediting_542308chr7_44801990_+3.08018536489471e-060.39614094206469....
LUADCAediting_542308chr7_44801990_+8.78560343247318e-170.475939340923614....
LUSCCAediting_542308chr7_44801990_+1.87332096667118e-100.42619715605953....
PRADCAediting_542308chr7_44801990_+0.01133210490495750.358879994281147....
HNSCCAediting_542308chr7_44801990_+9.02063068370269e-080.388633139113825....
STADCAediting_542308chr7_44801990_+0.0160693458187060.211607808204245....
THCACAediting_542308chr7_44801990_+0.01190998146628070.271640689379262....
UCECCAediting_542308chr7_44801990_+0.009210131324725650.267269016363588....
PAADCAediting_542308chr7_44801990_+0.02619942415429290.271595947897105....
PCPGCAediting_542308chr7_44801990_+0.001432357288104450.293903519014657....
SKCMCAediting_542308chr7_44801990_+7.48493517118155e-060.399325217023373....
SARCCAediting_542308chr7_44801990_+0.0002861475460086490.429561256488111....
TGCTCAediting_542308chr7_44801990_+4.07020668362112e-070.555574794978389....
BLCACAediting_542320chr7_44802329_+3.785837795672e-270.522939791542678....
LGGCAediting_542320chr7_44802329_+3.51793732562368e-120.2984620321858310.00214970658768430.134157499925162..
BRCACAediting_542320chr7_44802329_+2.05041916882607e-640.484477238572499....
LIHCCAediting_542320chr7_44802329_+7.70831392664587e-150.401575034328605....
CESCCAediting_542320chr7_44802329_+1.12916525409589e-180.487696535576454..0.01252405102445760.14672386825233
LUADCAediting_542320chr7_44802329_+3.82499321934873e-240.430391872882099....
COADCAediting_542320chr7_44802329_+5.37222274353424e-190.4262063962355110.04628861431129480.099951741952844..
LUSCCAediting_542320chr7_44802329_+1.19430832082086e-250.45457776956938..0.005288446211641820.127642189149925
GBMCAediting_542320chr7_44802329_+4.40782507987417e-070.380052726263834....
PRADCAediting_542320chr7_44802329_+1.41190271549619e-240.453179088206612....
HNSCCAediting_542320chr7_44802329_+2.35372260520816e-210.416100895313313....
STADCAediting_542320chr7_44802329_+4.15546322212913e-100.322485213148277....
THCACAediting_542320chr7_44802329_+7.21054192324821e-120.307920444421649....
KIRCCAediting_542320chr7_44802329_+6.40426186052875e-140.321794964193844....
UCECCAediting_542320chr7_44802329_+1.93061435418079e-230.462023054107755....
KIRPCAediting_542320chr7_44802329_+8.52437110099809e-070.30839416604422....
ACCCAediting_542320chr7_44802329_+1.18413371675657e-100.6925111014911510.04984852182105030.242432055162176..
ESCACAediting_542320chr7_44802329_+1.00174596967214e-080.436300192538781....
LAMLCAediting_542320chr7_44802329_+0.0009860930082423550.295834441011707....
OVCAediting_542320chr7_44802329_+4.54076999643038e-100.315569194913507....
PAADCAediting_542320chr7_44802329_+1.54776320781018e-080.415838814950922....
PCPGCAediting_542320chr7_44802329_+2.48071283679606e-120.505173691658864....
SKCMCAediting_542320chr7_44802329_+8.86882832702769e-350.535648559641319....
UVMCAediting_542320chr7_44802329_+1.42404741697822e-050.496619170718256....
MESOCAediting_542320chr7_44802329_+7.69944841426551e-070.508897367191581....
READCAediting_542320chr7_44802329_+0.0002410555868898670.304536054204761....
SARCCAediting_542320chr7_44802329_+4.45533920031603e-160.492634042201038....
TGCTCAediting_542320chr7_44802329_+8.40017985888036e-150.5854715844145....
THYMCAediting_542320chr7_44802329_+5.69974119002246e-120.5928653816632..0.01601403638608270.227155620009837
BLCACAediting_542321chr7_44802332_+0.01001435868079920.215476741765437....
LGGCAediting_542321chr7_44802332_+0.003640219822343670.343105741358388....
BRCACAediting_542321chr7_44802332_+1.53967322837968e-120.269806424893421....
LIHCCAediting_542321chr7_44802332_+1.78744205284055e-080.382477591527566....
LUADCAediting_542321chr7_44802332_+1.56295489118603e-050.250257106369416....
COADCAediting_542321chr7_44802332_+0.002208595789942280.299743144374199....
LUSCCAediting_542321chr7_44802332_+0.000143098363082980.228982473535486....
HNSCCAediting_542321chr7_44802332_+0.007779261768599410.189592692313382....
PAADCAediting_542321chr7_44802332_+0.01864716986120680.267562004608418....
PCPGCAediting_542321chr7_44802332_+0.03347650438274550.211806546781052....
SKCMCAediting_542321chr7_44802332_+....0.02303821968738030.186132407736768
TGCTCAediting_542321chr7_44802332_+4.82230352691606e-060.43929248303623....
BRCACAediting_542322chr7_44802334_+1.38845608221332e-150.359644137873694....
LIHCCAediting_542322chr7_44802334_+0.0004524684837960980.262356687017728....
CESCCAediting_542322chr7_44802334_+0.03255340375814780.224313008895825....
LUADCAediting_542322chr7_44802334_+1.18850022961466e-050.313426146239016....
COADCAediting_542322chr7_44802334_+0.005687102566767950.324989552276477....
LUSCCAediting_542322chr7_44802334_+1.58342814351057e-050.3253907178686210.0325482642200160.16453050376242..
KIRCCAediting_542322chr7_44802334_+0.001551496318588470.276961648811784....
UCECCAediting_542322chr7_44802334_+0.04993675528125520.190929336000303..0.01055997668459080.247410973994841
TGCTCAediting_542322chr7_44802334_+0.007703207993359150.322865436267454....
BRCACAediting_542329chr7_44802423_+0.001267865924673270.253426430780373....
LIHCCAediting_542329chr7_44802423_+0.0001372961082067920.513420645731677....
LUADCAediting_542329chr7_44802423_+0.005600653338638160.382527353178371....
BLCACAediting_542330chr7_44802500_+5.93691078973285e-180.441667908475523....
LGGCAediting_542330chr7_44802500_+9.52302377978159e-170.506004636064305....
BRCACAediting_542330chr7_44802500_+5.92227242088071e-580.471248746710531....
LIHCCAediting_542330chr7_44802500_+3.39487584091474e-140.391522215465088....
CESCCAediting_542330chr7_44802500_+2.49671961794539e-100.376090890168943....
LUADCAediting_542330chr7_44802500_+5.97485364830785e-250.437646429888016....
COADCAediting_542330chr7_44802500_+5.77500849167986e-160.390704468415191....
LUSCCAediting_542330chr7_44802500_+2.40410449663644e-250.455883528209062..0.001633035365718250.145376396742656
GBMCAediting_542330chr7_44802500_+6.87959194669808e-060.415885693122775....
PRADCAediting_542330chr7_44802500_+1.01292166350915e-210.524881798300596....
HNSCCAediting_542330chr7_44802500_+5.86895677623659e-110.303194411571931....
STADCAediting_542330chr7_44802500_+1.54972625697607e-120.378911324945802....
THCACAediting_542330chr7_44802500_+1.09190269484287e-050.259483172843222....
KIRCCAediting_542330chr7_44802500_+0.005627501448497130.130180518391802....
UCECCAediting_542330chr7_44802500_+9.71642690748586e-250.464207673133885....
KIRPCAediting_542330chr7_44802500_+0.04042464921615920.175338362898915....
ESCACAediting_542330chr7_44802500_+4.73511758400755e-050.322707883886215....
OVCAediting_542330chr7_44802500_+3.44874418473841e-090.305429978122322....
PAADCAediting_542330chr7_44802500_+5.32487824000382e-070.391036760062432....
PCPGCAediting_542330chr7_44802500_+....0.04519787655309580.243718911903996
SKCMCAediting_542330chr7_44802500_+3.54536916241296e-180.430565353375758....
UVMCAediting_542330chr7_44802500_+0.02113556042622380.322168628302871....
MESOCAediting_542330chr7_44802500_+0.004432426478459640.318894374543513....
READCAediting_542330chr7_44802500_+6.06341515151201e-050.335704093030889....
SARCCAediting_542330chr7_44802500_+7.42956776056313e-100.405055570948876....
TGCTCAediting_542330chr7_44802500_+2.75885828273697e-210.681730543060121....
THYMCAediting_542330chr7_44802500_+1.44324839575513e-060.50325979926441....

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Relation with cancer stages for PPIA

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BLCApathologic_stageCAediting_542320chr7_44802329_+0.008332931359466850.137906179855358
KIRCpathologic_stageCAediting_542286chr7_44801789_+0.02808072129153480.135441368353995
KIRCpathologic_stageCAediting_542305chr7_44801920_+0.007138198817914560.12329423083527
KIRCpathologic_stageCAediting_542308chr7_44801990_+0.01926601294206260.171026720309192
KIRCpathologic_stageCAediting_542320chr7_44802329_+0.01346653989267480.108834331855664
KIRCpathologic_stageCAediting_542321chr7_44802332_+0.0003896248873322780.215528165525692
KIRCpathologic_stageCAediting_542330chr7_44802500_+1.54582894094518e-060.224497073161041
KIRPclinical_stageCAediting_542305chr7_44801920_+0.001500330281957690.274646145063003
KIRPclinical_stageCAediting_542320chr7_44802329_+0.0023132747479740.230849933767452
KIRPpathologic_stageCAediting_542305chr7_44801920_+0.0004158042440835740.267742279230258
KIRPpathologic_stageCAediting_542320chr7_44802329_+0.0001288477642338150.255291609823071
KIRPpathologic_stageCAediting_542330chr7_44802500_+0.0003095757723833090.312635781665712
LUADpathologic_stageCAediting_542321chr7_44802332_+0.01666024149776890.141227826874067
LUSCpathologic_stageCAediting_542320chr7_44802329_+0.0472135919827110.0912927941955784
LUSCpathologic_stageCAediting_542330chr7_44802500_+0.03344537118304970.0988609398069682
TGCTclinical_stageCAediting_542320chr7_44802329_+0.0276441731787019-0.252693918947037
TGCTpathologic_stageCAediting_542305chr7_44801920_+0.00978181779816078-0.320674207053871
TGCTpathologic_stageCAediting_542308chr7_44801990_+0.0229867138452709-0.363354671509142
TGCTpathologic_stageCAediting_542320chr7_44802329_+0.00218250948192485-0.350785914065655
THCApathologic_stageCAediting_542305chr7_44801920_+0.01335000285473140.136501060853087
THCApathologic_stageCAediting_542320chr7_44802329_+0.01679508526173060.110488426164789
THCApathologic_stageCAediting_542330chr7_44802500_+0.007448746854312680.160472755350903
UCECclinical_stageCAediting_542330chr7_44802500_+0.03598558452926810.100351503489264

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Relation with survival for PPIA

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LIHCCAediting_542305chr7_44801920_+0.03051033469023470.04397713.41959
HNSCCAediting_542286chr7_44801789_+0.01280098019213010.005855661.34819e-05
KIRPCAediting_542320chr7_44802329_+0.02383313556147290.044140510.0818
ESCACAediting_542321chr7_44802332_+0.009153868878681860.024413239.196
PCPGCAediting_542320chr7_44802329_+0.01157647072991050.049431274609.7

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RelatedDrugs for PPIA

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
PPIAP62937DB09130CopperPeptidyl-prolyl cis-trans isomerase A SmallMoleculeDrugapproved|investigational
PPIAP62937DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase A SmallMoleculeDrugapproved|investigational|vet_approved

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RelatedDiseases for PPIA

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
PPIAC0007131Non-Small Cell Lung Carcinoma1CTD_human
PPIAC0007137Squamous cell carcinoma1CTD_human
PPIAC0024623Malignant neoplasm of stomach1CTD_human
PPIAC0026640Mouth Neoplasms1CTD_human
PPIAC0027627Neoplasm Metastasis1CTD_human
PPIAC0036341Schizophrenia1PSYGENET
PPIAC0038356Stomach Neoplasms1CTD_human
PPIAC0153381Malignant neoplasm of mouth1CTD_human
PPIAC1708349Hereditary Diffuse Gastric Cancer1CTD_human