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Editing gene: CTSA (CAeditome ID:5476)

Gene summary for CTSA

Gene summary

Gene information	Gene symbol	CTSA
	Gene ID	5476
	Gene name	cathepsin A
	Synonyms	GLB2\|GSL\|NGBE\|PPCA\|PPGB
	Cytomap	20q13.12
	Type of gene	protein-coding
	Description	lysosomal protective proteinbeta-galactosidase 2beta-galactosidase protective proteincarboxypeptidase Ccarboxypeptidase Y-like kininasecarboxypeptidase-Ldeamidaselysosomal carboxypeptidase Aprotective protein cathepsin Aurinary kininase
	Modification date	20210518
	UniProtAcc	P10619
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
CTSA	GO:0006508	Lysosomal protective protein	12505983
CTSA	GO:0043231	Lysosomal protective protein	0000052

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RNA A-to-I events for CTSA

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000064601.15

RNA A-to-I editing events in Cancer.

CAediting_1431494(45895340, +), CAediting_1431495(45895344, +), CAediting_1431496(45895352, +), CAediting_1431497(45895360, +), CAediting_1431498(45895371, +), CAediting_1431499(45895385, +), CAediting_1431500(45895388, +), CAediting_1431501(45895390, +), CAediting_1431502(45895395, +), CAediting_1431503(45895400, +), CAediting_1431504(45895407, +), CAediting_1431505(45895408, +), CAediting_1431506(45895420, +), CAediting_1431507(45895421, +), CAediting_1431508(45895424, +), CAediting_1431509(45895441, +), CAediting_1431510(45895444, +), CAediting_1431511(45895454, +), CAediting_1431512(45895462, +), CAediting_1431513(45895474, +), CAediting_1431514(45895475, +), CAediting_1431515(45895478, +), CAediting_1431516(45895515, +), CAediting_1431517(45895547, +), CAediting_1431518(45895548, +), CAediting_1431519(45895552, +), CAediting_1431520(45895560, +), CAediting_1431521(45895565, +), CAediting_1431522(45895573, +), CAediting_1431523(45895575, +), CAediting_1431524(45895578, +), CAediting_1431525(45895587, +), CAediting_1431526(45895609, +), CAediting_1431527(45895615, +), CAediting_1431528(45895655, +), CAediting_1431529(45895666, +), CAediting_1431530(45895667, +), CAediting_1431531(45895674, +), CAediting_1431532(45895680, +), CAediting_1431533(45895681, +), CAediting_1431534(45895693, +), CAediting_1431535(45895698, +), CAediting_1431536(45895703, +), CAediting_1431537(45895707, +), CAediting_1431538(45895720, +), CAediting_1431539(45895722, +), CAediting_1431540(45895726, +), CAediting_1431541(45895746, +), CAediting_1431542(45895747, +), CAediting_1431543(45895768, +), CAediting_1431544(45895770, +), CAediting_1431545(45895782, +), CAediting_1431546(45895794, +), CAediting_1431547(45895805, +), CAediting_1431548(45895806, +), CAediting_1431549(45895819, +), CAediting_1431550(45895820, +), CAediting_1431551(45895823, +), CAediting_1431552(45895845, +), CAediting_1431553(45895847, +), CAediting_1431554(45895859, +), CAediting_1431555(45895861, +), CAediting_1431556(45895866, +), CAediting_1431557(45895875, +), CAediting_1431558(45895923, +), CAediting_1431559(45895931, +), CAediting_1431560(45895939, +), CAediting_1431561(45895940, +), CAediting_1431562(45895948, +), CAediting_1431563(45895956, +), CAediting_1431564(45895962, +), CAediting_1431565(45895971, +), CAediting_1431566(45895972, +), CAediting_1431567(45895975, +), CAediting_1431568(45895980, +), CAediting_1431569(45895985, +), CAediting_1431570(45895994, +), CAediting_1431571(45895996, +), CAediting_1431572(45895999, +), CAediting_1431573(45896008, +), CAediting_1431574(45896009, +), CAediting_1431575(45896014, +), CAediting_1431576(45896015, +), CAediting_1431577(45896018, +), CAediting_1431578(45896019, +), CAediting_1431579(45896030, +), CAediting_1431580(45896035, +), CAediting_1431581(45896036, +), CAediting_1431582(45896048, +), CAediting_1431583(45896052, +), CAediting_1431584(45896068, +), CAediting_1431585(45896074, +), CAediting_1431586(45896075, +), CAediting_1431587(45896080, +), CAediting_1431588(45896084, +), CAediting_1431589(45896088, +), CAediting_1431590(45896091, +), CAediting_1431591(45896097, +), CAediting_1431592(45896101, +), CAediting_1431593(45896104, +), CAediting_1431594(45896106, +), CAediting_1431595(45896115, +), CAediting_1431596(45896116, +), CAediting_1431597(45896120, +), CAediting_1431598(45896123, +), CAediting_1431599(45896127, +), CAediting_1431600(45896136, +), CAediting_1431601(45896140, +), CAediting_1431602(45896174, +), CAediting_1431603(45896179, +), CAediting_1431604(45896185, +), CAediting_1431605(45896186, +), CAediting_1431606(45896191, +), CAediting_1431607(45896204, +), CAediting_1431608(45896454, +), CAediting_1431609(45896456, +), CAediting_1431610(45896460, +), CAediting_1431611(45896497, +), CAediting_1431612(45896512, +), CAediting_1431613(45896513, +), CAediting_1431614(45896532, +), CAediting_1431615(45896533, +), CAediting_1431616(45896550, +), CAediting_1431617(45896559, +), CAediting_1431618(45896572, +), CAediting_1431619(45896574, +), CAediting_1431620(45896578, +), CAediting_1431621(45896626, +), CAediting_1431622(45896661, +), CAediting_1431623(45896676, +), CAediting_1431624(45896697, +), CAediting_1431625(45896698, +), CAediting_1431626(45896699, +), CAediting_1431627(45896711, +),

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RNA editing positional annotations for CTSA using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1431494	chr20_45895340_+	ncRNA_intronic
CAediting_1431495	chr20_45895344_+	ncRNA_intronic
CAediting_1431496	chr20_45895352_+	ncRNA_intronic
CAediting_1431497	chr20_45895360_+	ncRNA_intronic
CAediting_1431498	chr20_45895371_+	ncRNA_intronic
CAediting_1431499	chr20_45895385_+	ncRNA_intronic
CAediting_1431500	chr20_45895388_+	ncRNA_intronic
CAediting_1431501	chr20_45895390_+	ncRNA_intronic
CAediting_1431502	chr20_45895395_+	ncRNA_intronic
CAediting_1431503	chr20_45895400_+	ncRNA_intronic
CAediting_1431504	chr20_45895407_+	ncRNA_intronic
CAediting_1431505	chr20_45895408_+	ncRNA_intronic
CAediting_1431506	chr20_45895420_+	ncRNA_intronic
CAediting_1431507	chr20_45895421_+	ncRNA_intronic
CAediting_1431508	chr20_45895424_+	ncRNA_intronic
CAediting_1431509	chr20_45895441_+	ncRNA_intronic
CAediting_1431510	chr20_45895444_+	ncRNA_intronic
CAediting_1431511	chr20_45895454_+	ncRNA_intronic
CAediting_1431512	chr20_45895462_+	ncRNA_intronic
CAediting_1431513	chr20_45895474_+	ncRNA_intronic
CAediting_1431514	chr20_45895475_+	ncRNA_intronic
CAediting_1431515	chr20_45895478_+	ncRNA_intronic
CAediting_1431516	chr20_45895515_+	ncRNA_intronic
CAediting_1431517	chr20_45895547_+	ncRNA_intronic
CAediting_1431518	chr20_45895548_+	ncRNA_intronic
CAediting_1431519	chr20_45895552_+	ncRNA_intronic
CAediting_1431520	chr20_45895560_+	ncRNA_intronic
CAediting_1431521	chr20_45895565_+	ncRNA_intronic
CAediting_1431522	chr20_45895573_+	ncRNA_intronic
CAediting_1431523	chr20_45895575_+	ncRNA_intronic
CAediting_1431524	chr20_45895578_+	ncRNA_intronic
CAediting_1431525	chr20_45895587_+	ncRNA_intronic
CAediting_1431526	chr20_45895609_+	ncRNA_intronic
CAediting_1431527	chr20_45895615_+	ncRNA_intronic
CAediting_1431528	chr20_45895655_+	ncRNA_intronic
CAediting_1431529	chr20_45895666_+	ncRNA_intronic
CAediting_1431530	chr20_45895667_+	ncRNA_intronic
CAediting_1431531	chr20_45895674_+	ncRNA_intronic
CAediting_1431532	chr20_45895680_+	ncRNA_intronic
CAediting_1431533	chr20_45895681_+	ncRNA_intronic
CAediting_1431534	chr20_45895693_+	ncRNA_intronic
CAediting_1431535	chr20_45895698_+	ncRNA_intronic
CAediting_1431536	chr20_45895703_+	ncRNA_intronic
CAediting_1431537	chr20_45895707_+	ncRNA_intronic
CAediting_1431538	chr20_45895720_+	ncRNA_intronic
CAediting_1431539	chr20_45895722_+	ncRNA_intronic
CAediting_1431540	chr20_45895726_+	ncRNA_intronic
CAediting_1431541	chr20_45895746_+	ncRNA_intronic
CAediting_1431542	chr20_45895747_+	ncRNA_intronic
CAediting_1431543	chr20_45895768_+	ncRNA_intronic
CAediting_1431544	chr20_45895770_+	ncRNA_intronic
CAediting_1431545	chr20_45895782_+	ncRNA_intronic
CAediting_1431546	chr20_45895794_+	ncRNA_intronic
CAediting_1431547	chr20_45895805_+	ncRNA_intronic
CAediting_1431548	chr20_45895806_+	ncRNA_intronic
CAediting_1431549	chr20_45895819_+	ncRNA_intronic
CAediting_1431550	chr20_45895820_+	ncRNA_intronic
CAediting_1431551	chr20_45895823_+	ncRNA_intronic
CAediting_1431552	chr20_45895845_+	ncRNA_intronic
CAediting_1431553	chr20_45895847_+	ncRNA_intronic
CAediting_1431554	chr20_45895859_+	ncRNA_intronic
CAediting_1431555	chr20_45895861_+	ncRNA_intronic
CAediting_1431556	chr20_45895866_+	ncRNA_intronic
CAediting_1431557	chr20_45895875_+	ncRNA_intronic
CAediting_1431558	chr20_45895923_+	ncRNA_intronic
CAediting_1431559	chr20_45895931_+	ncRNA_intronic
CAediting_1431560	chr20_45895939_+	ncRNA_intronic
CAediting_1431561	chr20_45895940_+	ncRNA_intronic
CAediting_1431562	chr20_45895948_+	ncRNA_intronic
CAediting_1431563	chr20_45895956_+	ncRNA_intronic
CAediting_1431564	chr20_45895962_+	ncRNA_intronic
CAediting_1431565	chr20_45895971_+	ncRNA_intronic
CAediting_1431566	chr20_45895972_+	ncRNA_intronic
CAediting_1431567	chr20_45895975_+	ncRNA_intronic
CAediting_1431568	chr20_45895980_+	ncRNA_intronic
CAediting_1431569	chr20_45895985_+	ncRNA_intronic
CAediting_1431570	chr20_45895994_+	ncRNA_intronic
CAediting_1431571	chr20_45895996_+	ncRNA_intronic
CAediting_1431572	chr20_45895999_+	ncRNA_intronic
CAediting_1431573	chr20_45896008_+	ncRNA_intronic
CAediting_1431574	chr20_45896009_+	ncRNA_intronic
CAediting_1431575	chr20_45896014_+	ncRNA_intronic
CAediting_1431576	chr20_45896015_+	ncRNA_intronic
CAediting_1431577	chr20_45896018_+	ncRNA_intronic
CAediting_1431578	chr20_45896019_+	ncRNA_intronic
CAediting_1431579	chr20_45896030_+	ncRNA_intronic
CAediting_1431580	chr20_45896035_+	ncRNA_intronic
CAediting_1431581	chr20_45896036_+	ncRNA_intronic
CAediting_1431582	chr20_45896048_+	ncRNA_intronic
CAediting_1431583	chr20_45896052_+	ncRNA_intronic
CAediting_1431584	chr20_45896068_+	ncRNA_intronic
CAediting_1431585	chr20_45896074_+	ncRNA_intronic
CAediting_1431586	chr20_45896075_+	ncRNA_intronic
CAediting_1431587	chr20_45896080_+	ncRNA_intronic
CAediting_1431588	chr20_45896084_+	ncRNA_intronic
CAediting_1431589	chr20_45896088_+	ncRNA_intronic
CAediting_1431590	chr20_45896091_+	ncRNA_intronic
CAediting_1431591	chr20_45896097_+	ncRNA_intronic
CAediting_1431592	chr20_45896101_+	ncRNA_intronic
CAediting_1431593	chr20_45896104_+	ncRNA_intronic
CAediting_1431594	chr20_45896106_+	ncRNA_intronic
CAediting_1431595	chr20_45896115_+	ncRNA_intronic
CAediting_1431596	chr20_45896116_+	ncRNA_intronic
CAediting_1431597	chr20_45896120_+	ncRNA_intronic
CAediting_1431598	chr20_45896123_+	ncRNA_intronic
CAediting_1431599	chr20_45896127_+	ncRNA_intronic
CAediting_1431600	chr20_45896136_+	ncRNA_intronic
CAediting_1431601	chr20_45896140_+	ncRNA_intronic
CAediting_1431602	chr20_45896174_+	ncRNA_intronic
CAediting_1431603	chr20_45896179_+	ncRNA_intronic
CAediting_1431604	chr20_45896185_+	ncRNA_intronic
CAediting_1431605	chr20_45896186_+	ncRNA_intronic
CAediting_1431606	chr20_45896191_+	ncRNA_intronic
CAediting_1431607	chr20_45896204_+	ncRNA_intronic
CAediting_1431608	chr20_45896454_+	ncRNA_exonic
CAediting_1431609	chr20_45896456_+	ncRNA_exonic
CAediting_1431610	chr20_45896460_+	ncRNA_exonic
CAediting_1431611	chr20_45896497_+	ncRNA_exonic
CAediting_1431612	chr20_45896512_+	ncRNA_exonic
CAediting_1431613	chr20_45896513_+	ncRNA_exonic
CAediting_1431614	chr20_45896532_+	ncRNA_exonic
CAediting_1431615	chr20_45896533_+	ncRNA_exonic
CAediting_1431616	chr20_45896550_+	ncRNA_exonic
CAediting_1431617	chr20_45896559_+	ncRNA_exonic
CAediting_1431618	chr20_45896572_+	ncRNA_exonic
CAediting_1431619	chr20_45896574_+	ncRNA_exonic
CAediting_1431620	chr20_45896578_+	ncRNA_exonic
CAediting_1431621	chr20_45896626_+	ncRNA_exonic
CAediting_1431622	chr20_45896661_+	ncRNA_exonic
CAediting_1431623	chr20_45896676_+	ncRNA_exonic
CAediting_1431624	chr20_45896697_+	ncRNA_exonic
CAediting_1431625	chr20_45896698_+	ncRNA_exonic
CAediting_1431626	chr20_45896699_+	ncRNA_exonic
CAediting_1431627	chr20_45896711_+	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1431494	chr20_45895340_+	SINE	Alu	AluJo
CAediting_1431495	chr20_45895344_+	SINE	Alu	AluJo
CAediting_1431496	chr20_45895352_+	SINE	Alu	AluJo
CAediting_1431497	chr20_45895360_+	SINE	Alu	AluJo
CAediting_1431498	chr20_45895371_+	SINE	Alu	AluJo
CAediting_1431499	chr20_45895385_+	SINE	Alu	AluJo
CAediting_1431500	chr20_45895388_+	SINE	Alu	AluJo
CAediting_1431501	chr20_45895390_+	SINE	Alu	AluJo
CAediting_1431502	chr20_45895395_+	SINE	Alu	AluJo
CAediting_1431503	chr20_45895400_+	SINE	Alu	AluJo
CAediting_1431504	chr20_45895407_+	SINE	Alu	AluJo
CAediting_1431505	chr20_45895408_+	SINE	Alu	AluJo
CAediting_1431506	chr20_45895420_+	SINE	Alu	AluJo
CAediting_1431507	chr20_45895421_+	SINE	Alu	AluJo
CAediting_1431508	chr20_45895424_+	SINE	Alu	AluJo
CAediting_1431509	chr20_45895441_+	SINE	Alu	AluJo
CAediting_1431510	chr20_45895444_+	SINE	Alu	AluJo
CAediting_1431511	chr20_45895454_+	SINE	Alu	AluJo
CAediting_1431512	chr20_45895462_+	SINE	Alu	AluJo
CAediting_1431513	chr20_45895474_+	SINE	Alu	AluJo
CAediting_1431514	chr20_45895475_+	SINE	Alu	AluJo
CAediting_1431515	chr20_45895478_+	SINE	Alu	AluJo
CAediting_1431516	chr20_45895515_+	SINE	Alu	AluJo
CAediting_1431517	chr20_45895547_+	SINE	Alu	AluJo
CAediting_1431518	chr20_45895548_+	SINE	Alu	AluJo
CAediting_1431519	chr20_45895552_+	SINE	Alu	AluJo
CAediting_1431520	chr20_45895560_+	SINE	Alu	AluJo
CAediting_1431521	chr20_45895565_+	SINE	Alu	AluJo
CAediting_1431522	chr20_45895573_+	SINE	Alu	AluJo
CAediting_1431523	chr20_45895575_+	SINE	Alu	AluJo
CAediting_1431524	chr20_45895578_+	SINE	Alu	AluJo
CAediting_1431525	chr20_45895587_+	SINE	Alu	AluJo
CAediting_1431526	chr20_45895609_+	SINE	Alu	AluJo
CAediting_1431528	chr20_45895655_+	SINE	Alu	AluJr
CAediting_1431529	chr20_45895666_+	SINE	Alu	AluJr
CAediting_1431530	chr20_45895667_+	SINE	Alu	AluJr
CAediting_1431531	chr20_45895674_+	SINE	Alu	AluJr
CAediting_1431532	chr20_45895680_+	SINE	Alu	AluJr
CAediting_1431533	chr20_45895681_+	SINE	Alu	AluJr
CAediting_1431534	chr20_45895693_+	SINE	Alu	AluJr
CAediting_1431535	chr20_45895698_+	SINE	Alu	AluJr
CAediting_1431536	chr20_45895703_+	SINE	Alu	AluJr
CAediting_1431537	chr20_45895707_+	SINE	Alu	AluJr
CAediting_1431538	chr20_45895720_+	SINE	Alu	AluJr
CAediting_1431539	chr20_45895722_+	SINE	Alu	AluJr
CAediting_1431540	chr20_45895726_+	SINE	Alu	AluJr
CAediting_1431541	chr20_45895746_+	SINE	Alu	AluJr
CAediting_1431542	chr20_45895747_+	SINE	Alu	AluJr
CAediting_1431543	chr20_45895768_+	SINE	Alu	AluJr
CAediting_1431544	chr20_45895770_+	SINE	Alu	AluJr
CAediting_1431545	chr20_45895782_+	SINE	Alu	AluJr
CAediting_1431546	chr20_45895794_+	SINE	Alu	AluJr
CAediting_1431547	chr20_45895805_+	SINE	Alu	AluJr
CAediting_1431548	chr20_45895806_+	SINE	Alu	AluJr
CAediting_1431549	chr20_45895819_+	SINE	Alu	AluJr
CAediting_1431550	chr20_45895820_+	SINE	Alu	AluJr
CAediting_1431551	chr20_45895823_+	SINE	Alu	AluJr
CAediting_1431552	chr20_45895845_+	SINE	Alu	AluJr
CAediting_1431553	chr20_45895847_+	SINE	Alu	AluJr
CAediting_1431554	chr20_45895859_+	SINE	Alu	AluJr
CAediting_1431555	chr20_45895861_+	SINE	Alu	AluJr
CAediting_1431556	chr20_45895866_+	SINE	Alu	AluJr
CAediting_1431557	chr20_45895875_+	SINE	Alu	AluJr
CAediting_1431558	chr20_45895923_+	SINE	Alu	AluSq
CAediting_1431559	chr20_45895931_+	SINE	Alu	AluSq
CAediting_1431560	chr20_45895939_+	SINE	Alu	AluSq
CAediting_1431561	chr20_45895940_+	SINE	Alu	AluSq
CAediting_1431562	chr20_45895948_+	SINE	Alu	AluSq
CAediting_1431563	chr20_45895956_+	SINE	Alu	AluSq
CAediting_1431564	chr20_45895962_+	SINE	Alu	AluSq
CAediting_1431565	chr20_45895971_+	SINE	Alu	AluSq
CAediting_1431566	chr20_45895972_+	SINE	Alu	AluSq
CAediting_1431567	chr20_45895975_+	SINE	Alu	AluSq
CAediting_1431568	chr20_45895980_+	SINE	Alu	AluSq
CAediting_1431569	chr20_45895985_+	SINE	Alu	AluSq
CAediting_1431570	chr20_45895994_+	SINE	Alu	AluSq
CAediting_1431571	chr20_45895996_+	SINE	Alu	AluSq
CAediting_1431572	chr20_45895999_+	SINE	Alu	AluSq
CAediting_1431573	chr20_45896008_+	SINE	Alu	AluSq
CAediting_1431574	chr20_45896009_+	SINE	Alu	AluSq
CAediting_1431575	chr20_45896014_+	SINE	Alu	AluSq
CAediting_1431576	chr20_45896015_+	SINE	Alu	AluSq
CAediting_1431577	chr20_45896018_+	SINE	Alu	AluSq
CAediting_1431578	chr20_45896019_+	SINE	Alu	AluSq
CAediting_1431579	chr20_45896030_+	SINE	Alu	AluSq
CAediting_1431580	chr20_45896035_+	SINE	Alu	AluSq
CAediting_1431581	chr20_45896036_+	SINE	Alu	AluSq
CAediting_1431582	chr20_45896048_+	SINE	Alu	AluSq
CAediting_1431583	chr20_45896052_+	SINE	Alu	AluSq
CAediting_1431584	chr20_45896068_+	SINE	Alu	AluSq
CAediting_1431585	chr20_45896074_+	SINE	Alu	AluSq
CAediting_1431586	chr20_45896075_+	SINE	Alu	AluSq
CAediting_1431587	chr20_45896080_+	SINE	Alu	AluSq
CAediting_1431588	chr20_45896084_+	SINE	Alu	AluSq
CAediting_1431589	chr20_45896088_+	SINE	Alu	AluSq
CAediting_1431590	chr20_45896091_+	SINE	Alu	AluSq
CAediting_1431591	chr20_45896097_+	SINE	Alu	AluSq
CAediting_1431592	chr20_45896101_+	SINE	Alu	AluSq
CAediting_1431593	chr20_45896104_+	SINE	Alu	AluSq
CAediting_1431594	chr20_45896106_+	SINE	Alu	AluSq
CAediting_1431595	chr20_45896115_+	SINE	Alu	AluSq
CAediting_1431596	chr20_45896116_+	SINE	Alu	AluSq
CAediting_1431597	chr20_45896120_+	SINE	Alu	AluSq
CAediting_1431598	chr20_45896123_+	SINE	Alu	AluSq
CAediting_1431599	chr20_45896127_+	SINE	Alu	AluSq
CAediting_1431600	chr20_45896136_+	SINE	Alu	AluSq
CAediting_1431601	chr20_45896140_+	SINE	Alu	AluSq
CAediting_1431602	chr20_45896174_+	SINE	Alu	AluSq
CAediting_1431603	chr20_45896179_+	SINE	Alu	AluSq
CAediting_1431604	chr20_45896185_+	SINE	Alu	AluSq
CAediting_1431605	chr20_45896186_+	SINE	Alu	AluSq
CAediting_1431606	chr20_45896191_+	SINE	Alu	AluSq
CAediting_1431607	chr20_45896204_+	SINE	Alu	AluSq
CAediting_1431608	chr20_45896454_+	SINE	Alu	AluSg
CAediting_1431609	chr20_45896456_+	SINE	Alu	AluSg
CAediting_1431610	chr20_45896460_+	SINE	Alu	AluSg
CAediting_1431611	chr20_45896497_+	SINE	Alu	AluSg
CAediting_1431612	chr20_45896512_+	SINE	Alu	AluSg
CAediting_1431613	chr20_45896513_+	SINE	Alu	AluSg
CAediting_1431614	chr20_45896532_+	SINE	Alu	AluSg
CAediting_1431615	chr20_45896533_+	SINE	Alu	AluSg
CAediting_1431616	chr20_45896550_+	SINE	Alu	AluSg
CAediting_1431617	chr20_45896559_+	SINE	Alu	AluSg
CAediting_1431618	chr20_45896572_+	SINE	Alu	AluSg
CAediting_1431619	chr20_45896574_+	SINE	Alu	AluSg
CAediting_1431620	chr20_45896578_+	SINE	Alu	AluSg
CAediting_1431621	chr20_45896626_+	SINE	Alu	AluSg
CAediting_1431622	chr20_45896661_+	SINE	Alu	AluSg
CAediting_1431623	chr20_45896676_+	SINE	Alu	AluSg
CAediting_1431624	chr20_45896697_+	SINE	Alu	AluSg
CAediting_1431625	chr20_45896698_+	SINE	Alu	AluSg
CAediting_1431626	chr20_45896699_+	SINE	Alu	AluSg
CAediting_1431627	chr20_45896711_+	SINE	Alu	AluSg

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RNA A-to-I editing events in the alternative splicing sites for CTSA

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000064601.15.CTSA.

Correlation between RNA A-to-I editing and PSI for ENSG00000064601.15.CTSA.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CTSA

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ACC.CAediting_1431568.ENSG00000064601.CTSA.png
Soverview

LAML.CAediting_1431568.ENSG00000064601.CTSA.png
Soverview

OV.CAediting_1431550.ENSG00000064601.CTSA.png
Soverview

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Protein coding region RNA A-to-I editings for CTSA

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CTSA

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_77128	chr1_85133844_+	ENSG00000064601.15	ENST00000606788	hsa-miR-4423-3p	45894724	45894730	7mer-m8	45894711	45894731	145	-22.81
CAediting_1368054	chr19_46709310_-	ENSG00000064601.15	ENST00000606788	hsa-miR-320e	45898462	45898468	7mer-m8	45898453	45898469	146	-16.23
CAediting_1524209	chrX_134546392_-	ENSG00000064601.15	ENST00000606788	hsa-miR-503-5p	45898401	45898407	7mer-m8	45898386	45898408	146	-18.94

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CTSA

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for CTSA

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
STAD	CAediting_1431518	chr20_45895548_+	.	.	0.00266174083998456	0.280058304036615	.	.
BLCA	CAediting_1431531	chr20_45895674_+	0.0413072959315695	0.281295306824677	.	.	.	.
LGG	CAediting_1431531	chr20_45895674_+	.	.	0.00500606630440198	0.193004397783306	.	.
LUAD	CAediting_1431531	chr20_45895674_+	0.0227228834830746	0.187819419549514	.	.	.	.
GBM	CAediting_1431531	chr20_45895674_+	0.00584770144023276	0.247173656166183	.	.	.	.
ACC	CAediting_1431531	chr20_45895674_+	0.00153679101801532	0.42445665387613	.	.	.	.
ESCA	CAediting_1431531	chr20_45895674_+	.	.	0.0239318036238075	0.20694892646393	.	.
LAML	CAediting_1431531	chr20_45895674_+	0.00817259174415258	0.219621001387908	0.024918650149045	0.186867680338067	0.00100219102120061	0.27136130030405
OV	CAediting_1431531	chr20_45895674_+	0.0154017275962863	0.150126049864741	.	.	.	.
SKCM	CAediting_1431531	chr20_45895674_+	.	.	0.0235040125660277	0.184897106606667	.	.
LUAD	CAediting_1431547	chr20_45895805_+	.	.	0.0418237961564726	0.19531346167046	.	.
LUSC	CAediting_1431547	chr20_45895805_+	0.00488100301527681	0.374242339732505	.	.	.	.
STAD	CAediting_1431547	chr20_45895805_+	.	.	.	.	0.0181650328530699	0.185418338608285
KIRC	CAediting_1431547	chr20_45895805_+	.	.	0.00385114530185498	0.223165861481499	.	.
KIRP	CAediting_1431547	chr20_45895805_+	.	.	0.000677610574914788	0.396546152855092	.	.
ACC	CAediting_1431547	chr20_45895805_+	.	.	0.000180382339387953	0.496660689415687	.	.
ESCA	CAediting_1431547	chr20_45895805_+	.	.	0.022828297635432	0.23098234230234	.	.
LAML	CAediting_1431547	chr20_45895805_+	.	.	0.0383263602458611	0.191773907795418	.	.
OV	CAediting_1431547	chr20_45895805_+	0.0326303838492326	0.143466594780457	.	.	.	.
SKCM	CAediting_1431547	chr20_45895805_+	.	.	8.37767657365337e-05	0.374284709027217	.	.
COAD	CAediting_1431550	chr20_45895820_+	0.0451574567035732	0.188844313691577	.	.	.	.
GBM	CAediting_1431550	chr20_45895820_+	0.0232082071062227	0.234001753728519	.	.	.	.
STAD	CAediting_1431550	chr20_45895820_+	.	.	0.0437193909692973	0.141015044839055	.	.
KIRC	CAediting_1431550	chr20_45895820_+	.	.	0.0373119973135387	0.163261439293013	.	.
KIRP	CAediting_1431550	chr20_45895820_+	.	.	0.0189810854702862	0.29030938305254	.	.
ACC	CAediting_1431550	chr20_45895820_+	.	.	0.000624820700830722	0.450769069940896	.	.
LAML	CAediting_1431550	chr20_45895820_+	.	.	.	.	0.000491248048470352	0.309675128356531
OV	CAediting_1431550	chr20_45895820_+	0.0284843873931859	0.139407189167068	.	.	.	.
SKCM	CAediting_1431550	chr20_45895820_+	.	.	0.0379088973543473	0.208974236533848	.	.
STAD	CAediting_1431551	chr20_45895823_+	.	.	0.000318807322494591	0.439030094138783	.	.
KIRC	CAediting_1431551	chr20_45895823_+	.	.	0.0365706180974411	0.277579533545804	.	.
GBM	CAediting_1431561	chr20_45895940_+	0.0192862232547579	0.32357556549792	.	.	.	.
ESCA	CAediting_1431561	chr20_45895940_+	.	.	.	.	0.037510175252331	0.269231412869388
LGG	CAediting_1431586	chr20_45896075_+	.	.	0.000575198105577449	0.324551573786251	.	.
LUAD	CAediting_1431590	chr20_45896091_+	0.0398540057285614	0.237897738698247	.	.	.	.
STAD	CAediting_1431590	chr20_45896091_+	.	.	0.00399463151377893	0.229237697687849	.	.
ESCA	CAediting_1431590	chr20_45896091_+	0.0390487919208215	0.217954258192052	0.00218396902022386	0.31895267339742	.	.
GBM	CAediting_1431592	chr20_45896101_+	.	.	0.021692191751123	0.244493180420589	.	.
STAD	CAediting_1431592	chr20_45896101_+	.	.	0.00149298287384557	0.229455151761551	.	.
KIRP	CAediting_1431592	chr20_45896101_+	.	.	0.00082953953543353	0.441595869178265	.	.
ESCA	CAediting_1431592	chr20_45896101_+	.	.	0.000553807565835525	0.332931929028713	.	.
SKCM	CAediting_1431592	chr20_45896101_+	.	.	0.00282297602540283	0.354253145803978	.	.
LAML	CAediting_1431596	chr20_45896116_+	.	.	.	.	0.00416081197779138	0.319031307738457
STAD	CAediting_1431597	chr20_45896120_+	.	.	0.0297227757659137	0.145607705397696	.	.

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Relation with cancer stages for CTSA

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ACC	pathologic_stage	CAediting_1431531	chr20_45895674_+	0.00827139714363262	-0.36593340079534
ACC	pathologic_stage	CAediting_1431561	chr20_45895940_+	0.0284059909262758	-0.313250502042847
ESCA	pathologic_stage	CAediting_1431550	chr20_45895820_+	0.0340968503620156	0.213212523004641
ESCA	pathologic_stage	CAediting_1431568	chr20_45895980_+	0.00575316719636686	0.300630432256069
ESCA	pathologic_stage	CAediting_1431586	chr20_45896075_+	0.0146548058726906	0.311149105424588
KIRC	pathologic_stage	CAediting_1431547	chr20_45895805_+	0.0299574054838053	0.16854179503562
KIRC	pathologic_stage	CAediting_1431550	chr20_45895820_+	0.00149593476306459	0.246763326396002
KIRC	pathologic_stage	CAediting_1431586	chr20_45896075_+	0.000244315342718551	0.325036901322755
KIRC	pathologic_stage	CAediting_1431592	chr20_45896101_+	0.00817433137548353	0.236524021384481
KIRC	pathologic_stage	CAediting_1431595	chr20_45896115_+	0.0182938533266204	0.264937627918289
LUSC	pathologic_stage	CAediting_1431547	chr20_45895805_+	0.00915839256007743	0.348324847646704
OV	clinical_stage	CAediting_1431547	chr20_45895805_+	0.03446307175363	0.142649812954935
OV	clinical_stage	CAediting_1431561	chr20_45895940_+	0.0222417482164909	0.27103443136194
OV	clinical_stage	CAediting_1431567	chr20_45895975_+	0.00237928274364425	0.357499075864947
OV	clinical_stage	CAediting_1431568	chr20_45895980_+	0.0309511305534369	0.165080508172437
OV	clinical_stage	CAediting_1431579	chr20_45896030_+	0.0467329337142048	0.274444810350639
STAD	pathologic_stage	CAediting_1431586	chr20_45896075_+	0.0455475876856159	0.203532851065665

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Relation with survival for CTSA

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
STAD	CAediting_1431547	chr20_45895805_+	0.0397371003849532	0.0205866	6.09276
STAD	CAediting_1431550	chr20_45895820_+	0.000668893827757699	0.0299023	4.48278
STAD	CAediting_1431595	chr20_45896115_+	0.0104825093902773	0.0491772	4.60985
STAD	CAediting_1431597	chr20_45896120_+	0.0469537076193856	0.0186444	4.75031

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RelatedDrugs for CTSA

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CTSA

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CTSA	C0268233	GALACTOSIALIDOSIS	7	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene