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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: MPHOSPH8 (CAeditome ID:54737)

Gene summary for MPHOSPH8

check button Gene summary
Gene informationGene symbol

MPHOSPH8

Gene ID

54737

Gene nameM-phase phosphoprotein 8
SynonymsHSMPP8|TWA3|mpp8
Cytomap

13q12.11

Type of geneprotein-coding
DescriptionM-phase phosphoprotein 8M-phase phosphoprotein, mppM-phase phosphoprotein, mpp8two hybrid-associated protein 3 with RanBPM
Modification date20210518
UniProtAcc

Q99549

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
MPHOSPH8

GO:0003682

M-phase phosphoprotein 8

29211708

MPHOSPH8

GO:0035064

M-phase phosphoprotein 8

20871592

MPHOSPH8

GO:0045814

M-phase phosphoprotein 8

26022416

MPHOSPH8

GO:0045814

M-phase phosphoprotein 8

28581500

MPHOSPH8

GO:0045814

M-phase phosphoprotein 8

29211708

MPHOSPH8

GO:0090309

M-phase phosphoprotein 8

28581500

MPHOSPH8

GO:0090309

M-phase phosphoprotein 8

29211708

MPHOSPH8

GO:0000792

M-phase phosphoprotein 8

20871592

MPHOSPH8

GO:0000792

M-phase phosphoprotein 8

28581500

MPHOSPH8

GO:0005634

M-phase phosphoprotein 8

8885239

MPHOSPH8

GO:0005654

M-phase phosphoprotein 8

0000052

MPHOSPH8

GO:0005730

M-phase phosphoprotein 8

0000052

MPHOSPH8

GO:0005737

M-phase phosphoprotein 8

8885239

MPHOSPH8

GO:0005829

M-phase phosphoprotein 8

0000052

MPHOSPH8

GO:0005886

M-phase phosphoprotein 8

0000052

MPHOSPH8

GO:0000786

M-phase phosphoprotein 8

20871592


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RNA A-to-I events for MPHOSPH8

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000196199.12
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_950578(19640021, +), CAediting_950579(19645653, +), CAediting_950580(19645662, +), CAediting_950581(19652027, +), CAediting_950582(19659330, +), CAediting_950583(19659402, +), CAediting_950584(19659408, +), CAediting_950585(19659409, +), CAediting_950586(19659414, +), CAediting_950587(19659462, +), CAediting_950588(19659463, +), CAediting_950589(19659465, +), CAediting_950590(19659508, +), CAediting_950591(19659535, +), CAediting_950592(19659553, +), CAediting_950593(19659566, +), CAediting_950594(19659608, +), CAediting_950595(19659609, +), CAediting_950596(19659619, +), CAediting_950597(19659621, +), CAediting_950598(19660036, +), CAediting_950599(19660113, +), CAediting_950600(19660155, +), CAediting_950601(19660179, +), CAediting_950602(19660229, +), CAediting_950603(19660230, +), CAediting_950604(19660242, +), CAediting_950605(19660967, +), CAediting_950606(19661004, +), CAediting_950607(19661005, +), CAediting_950608(19661014, +), CAediting_950609(19661029, +), CAediting_950610(19661036, +), CAediting_950611(19661048, +), CAediting_950612(19661077, +), CAediting_950613(19661081, +), CAediting_950614(19661557, +), CAediting_950615(19665557, +), CAediting_950616(19669233, +), CAediting_950617(19669318, +), CAediting_950618(19669334, +), CAediting_950619(19669534, +), CAediting_950620(19669626, +), CAediting_950621(19669644, +), CAediting_950622(19669670, +), CAediting_950623(19669689, +), CAediting_950624(19669719, +), CAediting_950625(19669744, +), CAediting_950626(19669797, +), CAediting_950627(19670327, +), CAediting_950628(19670842, +), CAediting_950629(19670889, +), CAediting_950630(19670923, +), CAediting_950631(19670932, +), CAediting_950632(19670946, +), CAediting_950633(19670960, +), CAediting_950634(19670975, +), CAediting_950635(19670995, +), CAediting_950636(19671004, +), CAediting_950637(19671041, +), CAediting_950638(19671055, +), CAediting_950639(19671056, +), CAediting_950640(19672165, +), CAediting_950641(19672169, +), CAediting_950642(19672188, +), CAediting_950643(19672195, +), CAediting_950644(19672244, +), CAediting_950645(19672245, +), CAediting_950646(19672271, +), CAediting_950647(19672284, +), CAediting_950648(19672311, +), CAediting_950649(19672327, +), CAediting_950650(19672329, +), CAediting_950651(19672366, +), CAediting_950652(19672404, +), CAediting_950653(19672405, +), CAediting_950654(19672406, +), CAediting_950655(19672418, +), CAediting_950656(19672420, +), CAediting_950657(19672424, +), CAediting_950658(19672821, +), CAediting_950659(19672823, +), CAediting_950660(19672838, +), CAediting_950661(19672844, +), CAediting_950662(19672850, +), CAediting_950663(19672860, +), CAediting_950664(19672866, +), CAediting_950665(19672889, +), CAediting_950666(19672892, +), CAediting_950667(19672897, +), CAediting_950668(19672898, +), CAediting_950669(19672900, +), CAediting_950670(19672912, +), CAediting_950671(19672913, +), CAediting_950672(19672927, +), CAediting_950673(19672928, +), CAediting_950674(19672935, +), CAediting_950675(19672952, +), CAediting_950676(19672958, +), CAediting_950677(19672964, +), CAediting_950678(19672976, +), CAediting_950679(19672989, +), CAediting_950680(19672990, +), CAediting_950681(19672997, +), CAediting_950682(19673001, +), CAediting_950683(19673037, +), CAediting_950684(19673040, +), CAediting_950685(19673043, +), CAediting_950686(19673115, +), CAediting_950687(19673154, +), CAediting_950688(19673165, +), CAediting_950689(19673204, +), CAediting_950690(19673254, +),

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RNA editing positional annotations for MPHOSPH8 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_950578chr13_19640021_+intronic
CAediting_950579chr13_19645653_+intronic
CAediting_950580chr13_19645662_+intronic
CAediting_950581chr13_19652027_+intronic
CAediting_950582chr13_19659330_+ncRNA_intronic
CAediting_950583chr13_19659402_+ncRNA_intronic
CAediting_950584chr13_19659408_+ncRNA_intronic
CAediting_950585chr13_19659409_+ncRNA_intronic
CAediting_950586chr13_19659414_+ncRNA_intronic
CAediting_950587chr13_19659462_+ncRNA_intronic
CAediting_950588chr13_19659463_+ncRNA_intronic
CAediting_950589chr13_19659465_+ncRNA_intronic
CAediting_950590chr13_19659508_+ncRNA_intronic
CAediting_950591chr13_19659535_+ncRNA_intronic
CAediting_950592chr13_19659553_+ncRNA_intronic
CAediting_950593chr13_19659566_+ncRNA_intronic
CAediting_950594chr13_19659608_+ncRNA_intronic
CAediting_950595chr13_19659609_+ncRNA_intronic
CAediting_950596chr13_19659619_+ncRNA_intronic
CAediting_950597chr13_19659621_+ncRNA_intronic
CAediting_950598chr13_19660036_+ncRNA_intronic
CAediting_950599chr13_19660113_+ncRNA_intronic
CAediting_950600chr13_19660155_+ncRNA_intronic
CAediting_950601chr13_19660179_+ncRNA_intronic
CAediting_950602chr13_19660229_+ncRNA_intronic
CAediting_950603chr13_19660230_+ncRNA_intronic
CAediting_950604chr13_19660242_+ncRNA_intronic
CAediting_950605chr13_19660967_+ncRNA_exonic
CAediting_950606chr13_19661004_+ncRNA_exonic
CAediting_950607chr13_19661005_+ncRNA_exonic
CAediting_950608chr13_19661014_+ncRNA_exonic
CAediting_950609chr13_19661029_+ncRNA_exonic
CAediting_950610chr13_19661036_+ncRNA_exonic
CAediting_950611chr13_19661048_+ncRNA_exonic
CAediting_950612chr13_19661077_+ncRNA_exonic
CAediting_950613chr13_19661081_+ncRNA_exonic
CAediting_950614chr13_19661557_+intronic
CAediting_950615chr13_19665557_+intronic
CAediting_950616chr13_19669233_+intronic
CAediting_950617chr13_19669318_+intronic
CAediting_950618chr13_19669334_+intronic
CAediting_950619chr13_19669534_+intronic
CAediting_950620chr13_19669626_+intronic
CAediting_950621chr13_19669644_+intronic
CAediting_950622chr13_19669670_+intronic
CAediting_950623chr13_19669689_+intronic
CAediting_950624chr13_19669719_+intronic
CAediting_950625chr13_19669744_+intronic
CAediting_950626chr13_19669797_+intronic
CAediting_950627chr13_19670327_+exonic
CAediting_950628chr13_19670842_+exonic
CAediting_950629chr13_19670889_+exonic
CAediting_950630chr13_19670923_+exonic
CAediting_950631chr13_19670932_+exonic
CAediting_950632chr13_19670946_+exonic
CAediting_950633chr13_19670960_+exonic
CAediting_950634chr13_19670975_+ncRNA_exonic
CAediting_950635chr13_19670995_+ncRNA_exonic
CAediting_950636chr13_19671004_+ncRNA_exonic
CAediting_950637chr13_19671041_+ncRNA_exonic
CAediting_950638chr13_19671055_+ncRNA_exonic
CAediting_950639chr13_19671056_+ncRNA_exonic
CAediting_950640chr13_19672165_+UTR3
CAediting_950641chr13_19672169_+UTR3
CAediting_950642chr13_19672188_+UTR3
CAediting_950643chr13_19672195_+UTR3
CAediting_950644chr13_19672244_+UTR3
CAediting_950645chr13_19672245_+UTR3
CAediting_950646chr13_19672271_+UTR3
CAediting_950647chr13_19672284_+UTR3
CAediting_950648chr13_19672311_+UTR3
CAediting_950649chr13_19672327_+UTR3
CAediting_950650chr13_19672329_+UTR3
CAediting_950651chr13_19672366_+UTR3
CAediting_950652chr13_19672404_+UTR3
CAediting_950653chr13_19672405_+UTR3
CAediting_950654chr13_19672406_+UTR3
CAediting_950655chr13_19672418_+UTR3
CAediting_950656chr13_19672420_+UTR3
CAediting_950657chr13_19672424_+UTR3
CAediting_950658chr13_19672821_+UTR3
CAediting_950659chr13_19672823_+UTR3
CAediting_950660chr13_19672838_+UTR3
CAediting_950661chr13_19672844_+UTR3
CAediting_950662chr13_19672850_+UTR3
CAediting_950663chr13_19672860_+UTR3
CAediting_950664chr13_19672866_+UTR3
CAediting_950665chr13_19672889_+UTR3
CAediting_950666chr13_19672892_+UTR3
CAediting_950667chr13_19672897_+UTR3
CAediting_950668chr13_19672898_+UTR3
CAediting_950669chr13_19672900_+UTR3
CAediting_950670chr13_19672912_+UTR3
CAediting_950671chr13_19672913_+UTR3
CAediting_950672chr13_19672927_+UTR3
CAediting_950673chr13_19672928_+UTR3
CAediting_950674chr13_19672935_+UTR3
CAediting_950675chr13_19672952_+UTR3
CAediting_950676chr13_19672958_+UTR3
CAediting_950677chr13_19672964_+UTR3
CAediting_950678chr13_19672976_+UTR3
CAediting_950679chr13_19672989_+UTR3
CAediting_950680chr13_19672990_+UTR3
CAediting_950681chr13_19672997_+UTR3
CAediting_950682chr13_19673001_+UTR3
CAediting_950683chr13_19673037_+UTR3
CAediting_950684chr13_19673040_+UTR3
CAediting_950685chr13_19673043_+UTR3
CAediting_950686chr13_19673115_+UTR3
CAediting_950687chr13_19673154_+UTR3
CAediting_950688chr13_19673165_+UTR3
CAediting_950689chr13_19673204_+UTR3
CAediting_950690chr13_19673254_+UTR3

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_950578chr13_19640021_+SINEAluAluSz6
CAediting_950579chr13_19645653_+SINEAluAluSg
CAediting_950580chr13_19645662_+SINEAluAluSg
CAediting_950581chr13_19652027_+SINEAluAluSx3
CAediting_950583chr13_19659402_+SINEAluAluJb
CAediting_950584chr13_19659408_+SINEAluAluJb
CAediting_950585chr13_19659409_+SINEAluAluJb
CAediting_950586chr13_19659414_+SINEAluAluJb
CAediting_950587chr13_19659462_+SINEAluAluJb
CAediting_950588chr13_19659463_+SINEAluAluJb
CAediting_950589chr13_19659465_+SINEAluAluJb
CAediting_950590chr13_19659508_+SINEAluAluJb
CAediting_950591chr13_19659535_+SINEAluAluJb
CAediting_950592chr13_19659553_+SINEAluAluJb
CAediting_950593chr13_19659566_+SINEAluAluJb
CAediting_950594chr13_19659608_+SINEAluAluJb
CAediting_950595chr13_19659609_+SINEAluAluJb
CAediting_950596chr13_19659619_+SINEAluAluJb
CAediting_950597chr13_19659621_+SINEAluAluJb
CAediting_950598chr13_19660036_+SINEAluAluYf1
CAediting_950599chr13_19660113_+SINEAluAluYf1
CAediting_950600chr13_19660155_+SINEAluAluYf1
CAediting_950601chr13_19660179_+SINEAluAluYf1
CAediting_950602chr13_19660229_+SINEAluAluYf1
CAediting_950603chr13_19660230_+SINEAluAluYf1
CAediting_950604chr13_19660242_+SINEAluAluYf1
CAediting_950606chr13_19661004_+SINEAluFLAM_A
CAediting_950607chr13_19661005_+SINEAluFLAM_A
CAediting_950608chr13_19661014_+SINEAluFLAM_A
CAediting_950609chr13_19661029_+SINEAluFLAM_A
CAediting_950610chr13_19661036_+SINEAluFLAM_A
CAediting_950611chr13_19661048_+SINEAluFLAM_A
CAediting_950612chr13_19661077_+SINEAluFLAM_A
CAediting_950613chr13_19661081_+SINEAluFLAM_A
CAediting_950616chr13_19669233_+SINEAluAluSx
CAediting_950617chr13_19669318_+SINEAluAluSx
CAediting_950618chr13_19669334_+SINEAluAluSx
CAediting_950619chr13_19669534_+SINEAluAluSx1
CAediting_950620chr13_19669626_+SINEAluAluSx1
CAediting_950621chr13_19669644_+SINEAluAluSx1
CAediting_950622chr13_19669670_+SINEAluAluSx1
CAediting_950623chr13_19669689_+SINEAluAluSx1
CAediting_950624chr13_19669719_+SINEAluAluSx1
CAediting_950625chr13_19669744_+SINEAluAluSx1
CAediting_950626chr13_19669797_+SINEAluAluSx1
CAediting_950628chr13_19670842_+SINEAluAluJb
CAediting_950629chr13_19670889_+SINEAluAluJb
CAediting_950630chr13_19670923_+SINEAluAluJb
CAediting_950631chr13_19670932_+SINEAluAluJb
CAediting_950632chr13_19670946_+SINEAluAluJb
CAediting_950633chr13_19670960_+SINEAluAluJb
CAediting_950634chr13_19670975_+SINEAluAluJb
CAediting_950635chr13_19670995_+SINEAluAluJb
CAediting_950636chr13_19671004_+SINEAluAluJb
CAediting_950637chr13_19671041_+SINEAluAluJb
CAediting_950638chr13_19671055_+SINEAluAluJb
CAediting_950639chr13_19671056_+SINEAluAluJb
CAediting_950640chr13_19672165_+SINEAluAluSp
CAediting_950641chr13_19672169_+SINEAluAluSp
CAediting_950642chr13_19672188_+SINEAluAluSp
CAediting_950643chr13_19672195_+SINEAluAluSp
CAediting_950644chr13_19672244_+SINEAluAluSp
CAediting_950645chr13_19672245_+SINEAluAluSp
CAediting_950646chr13_19672271_+SINEAluAluSp
CAediting_950647chr13_19672284_+SINEAluAluSp
CAediting_950648chr13_19672311_+SINEAluAluSp
CAediting_950649chr13_19672327_+SINEAluAluSp
CAediting_950650chr13_19672329_+SINEAluAluSp
CAediting_950651chr13_19672366_+SINEAluAluSp
CAediting_950652chr13_19672404_+SINEAluAluSp
CAediting_950653chr13_19672405_+SINEAluAluSp
CAediting_950654chr13_19672406_+SINEAluAluSp
CAediting_950655chr13_19672418_+SINEAluAluSp
CAediting_950656chr13_19672420_+SINEAluAluSp
CAediting_950657chr13_19672424_+SINEAluAluSp
CAediting_950658chr13_19672821_+SINEAluAluJb
CAediting_950659chr13_19672823_+SINEAluAluJb
CAediting_950660chr13_19672838_+SINEAluAluJb
CAediting_950661chr13_19672844_+SINEAluAluJb
CAediting_950662chr13_19672850_+SINEAluAluJb
CAediting_950663chr13_19672860_+SINEAluAluJb
CAediting_950664chr13_19672866_+SINEAluAluJb
CAediting_950665chr13_19672889_+SINEAluAluJb
CAediting_950666chr13_19672892_+SINEAluAluJb
CAediting_950667chr13_19672897_+SINEAluAluJb
CAediting_950668chr13_19672898_+SINEAluAluJb
CAediting_950669chr13_19672900_+SINEAluAluJb
CAediting_950670chr13_19672912_+SINEAluAluJb
CAediting_950671chr13_19672913_+SINEAluAluJb
CAediting_950672chr13_19672927_+SINEAluAluJb
CAediting_950673chr13_19672928_+SINEAluAluJb
CAediting_950674chr13_19672935_+SINEAluAluJb
CAediting_950675chr13_19672952_+SINEAluAluJb
CAediting_950676chr13_19672958_+SINEAluAluJb
CAediting_950677chr13_19672964_+SINEAluAluJb
CAediting_950678chr13_19672976_+SINEAluAluJb
CAediting_950679chr13_19672989_+SINEAluAluJb
CAediting_950680chr13_19672990_+SINEAluAluJb
CAediting_950681chr13_19672997_+SINEAluAluJb
CAediting_950682chr13_19673001_+SINEAluAluJb
CAediting_950683chr13_19673037_+SINEAluAluJb
CAediting_950684chr13_19673040_+SINEAluAluJb
CAediting_950685chr13_19673043_+SINEAluAluJb

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RNA A-to-I editing events in the alternative splicing sites for MPHOSPH8

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
IRCAediting_950619chr13_19669534_+19669512:196695343SS3+0iACTTTTTTTTTTTTTTTTCAGGA-4.4ACTTTTTTTTTTTTTTTTCAGGG-4.81
ESCAediting_950628chr13_19670842_+19670823:196708453SS0+1iTTTTTTTTTTTTTGAAGACAGGG-14.69TTTTTTTTTTTTTGAAGACGGGG-5.94
IRCAediting_950628chr13_19670842_+19670823:196708453SS0+1iTTTTTTTTTTTTTGAAGACAGGG-14.69TTTTTTTTTTTTTGAAGACGGGG-5.94
IRCAediting_950664chr13_19672866_+19672865:196728735SS2+0iGAGGTTGGA2.95GGGGTTGGA-3.9
IRCAediting_950675chr13_19672952_+19672939:196729613SS0+7iCCAGATACTCAGGAGGCTGAGGT-27.69CCAGATACTCAGGGGGCTGAGGT-23.37
IRCAediting_950676chr13_19672958_+19672939:196729613SS0+1iCCAGATACTCAGGAGGCTGAGGT-27.69CCAGATACTCAGGAGGCTGGGGT-18.94
IRCAediting_950686chr13_19673115_+19673096:196731183SS0+1iTTGTTTTTTTTTTTTGAAAAGCC-1.74TTGTTTTTTTTTTTTGAAAGGCC7.01
IRCAediting_950686chr13_19673115_+19673100:196731223SS0+5iTTTTTTTTTTTGAAAAGCCAGAC-12.3TTTTTTTTTTTGAAAGGCCAGAC-15.09

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000196199.12.MPHOSPH8.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000196199.12.MPHOSPH8.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MPHOSPH8

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for MPHOSPH8

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for MPHOSPH8

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MPHOSPH8

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for MPHOSPH8

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BRCACAediting_950654chr13_19672406_+0.0009049735897920320.273630397769603....
LIHCCAediting_950654chr13_19672406_+0.01929329937549690.311862689077476....
OVCAediting_950654chr13_19672406_+0.02959620715348940.253067590552816....
BRCACAediting_950665chr13_19672889_+0.01056707326161410.125688585055813....
PRADCAediting_950665chr13_19672889_+..0.008137738275129440.328044895568398..
UCECCAediting_950665chr13_19672889_+0.03477760754497970.162505008105125....
SARCCAediting_950665chr13_19672889_+0.0005363853666126630.335273658073705....
BLCACAediting_950674chr13_19672935_+3.90925467803395e-250.487903526708692....
LGGCAediting_950674chr13_19672935_+5.1764853465234e-110.291775025945209....
BRCACAediting_950674chr13_19672935_+4.8096622707435e-560.453304245209606....
LIHCCAediting_950674chr13_19672935_+4.62481696402892e-090.300245571945696....
CESCCAediting_950674chr13_19672935_+0.0001234825919863390.218777553058486....
LUADCAediting_950674chr13_19672935_+1.67429292702225e-170.369967308437109....
COADCAediting_950674chr13_19672935_+2.87693383392093e-050.201648970199569....
LUSCCAediting_950674chr13_19672935_+4.49697924700791e-070.226520314562741....
GBMCAediting_950674chr13_19672935_+0.001331000627292940.247076639614307....
PRADCAediting_950674chr13_19672935_+5.56137899666572e-100.275459960624164....
HNSCCAediting_950674chr13_19672935_+1.44043584072373e-110.303352110439264....
STADCAediting_950674chr13_19672935_+4.20631784478826e-060.242424409847994....
THCACAediting_950674chr13_19672935_+1.26667308679126e-080.249576800503158....
KIRCCAediting_950674chr13_19672935_+1.26064654018078e-060.209049913250271....
UCECCAediting_950674chr13_19672935_+4.88103702740278e-180.363889757306889....
KIRPCAediting_950674chr13_19672935_+0.03335979716308870.128360162360065....
ACCCAediting_950674chr13_19672935_+3.24453587559772e-060.514334368793559....
ESCACAediting_950674chr13_19672935_+0.01298949549103170.196009993230258....
OVCAediting_950674chr13_19672935_+2.7226462459432e-050.218298317044912....
PAADCAediting_950674chr13_19672935_+3.25792133207679e-060.342565254165182....
PCPGCAediting_950674chr13_19672935_+2.22872082419855e-080.401975997834743....
SKCMCAediting_950674chr13_19672935_+4.77618674774466e-150.359429749473503....
UCSCAediting_950674chr13_19672935_+0.01364135736141640.340056907012144....
SARCCAediting_950674chr13_19672935_+1.47261472670145e-060.292880531197036....
TGCTCAediting_950674chr13_19672935_+1.24595984586485e-100.502061685755089....
THYMCAediting_950674chr13_19672935_+1.69912183442212e-050.386244387592451..0.01294576737381430.229156423496977
BLCACAediting_950678chr13_19672976_+2.54941079323378e-100.335688337984332....
LGGCAediting_950678chr13_19672976_+4.58931258368204e-100.301884012781547....
BRCACAediting_950678chr13_19672976_+4.20518647516043e-240.305802516081397....
LIHCCAediting_950678chr13_19672976_+0.002288539777353120.159605692260295....
CESCCAediting_950678chr13_19672976_+5.06795963675706e-050.240981210411712....
LUADCAediting_950678chr13_19672976_+0.0001800334375622950.171575554788666....
COADCAediting_950678chr13_19672976_+0.002440523837484940.151132656574613....
LUSCCAediting_950678chr13_19672976_+1.33710088005312e-060.224592608911321....
GBMCAediting_950678chr13_19672976_+0.01686821302159860.196172102550037....
PRADCAediting_950678chr13_19672976_+2.24123709616972e-090.275039974435153....
HNSCCAediting_950678chr13_19672976_+5.77011146983802e-060.215237328394634....
STADCAediting_950678chr13_19672976_+8.72103764968713e-050.212397932793436....
THCACAediting_950678chr13_19672976_+1.22040198366825e-080.258171050860877....
UCECCAediting_950678chr13_19672976_+1.75714676206193e-070.231006631460666....
KIRPCAediting_950678chr13_19672976_+0.04659812816816330.131359002343698....
ACCCAediting_950678chr13_19672976_+0.0003648949720265240.39351310993241....
OVCAediting_950678chr13_19672976_+0.001961605197336670.166847530099731....
PAADCAediting_950678chr13_19672976_+0.01491541615415960.187550575529169....
PCPGCAediting_950678chr13_19672976_+0.01105921009492550.189513473899280.04997708383381660.146743193729853..
SKCMCAediting_950678chr13_19672976_+1.36414948254921e-060.237309582566413....
READCAediting_950678chr13_19672976_+0.02549553175037790.186143153911571....
SARCCAediting_950678chr13_19672976_+0.009160704315552730.165844856984783....
TGCTCAediting_950678chr13_19672976_+4.60137796132248e-050.338437291462923....
THYMCAediting_950678chr13_19672976_+3.30427831135451e-050.393385518821506....
BRCACAediting_950680chr13_19672990_+0.005692393298532430.331896593041443....
BRCACAediting_950682chr13_19673001_+0.02484923961669040.126415316953068....
LUADCAediting_950682chr13_19673001_+2.32758167687789e-050.352997876490495....
UCECCAediting_950682chr13_19673001_+4.50041938831696e-050.2796070064715590.03097228389044430.150010497224819..
OVCAediting_950682chr13_19673001_+0.03281151799448930.145635667351186....
TGCTCAediting_950682chr13_19673001_+0.0001511224008406470.473668705846513....

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Relation with cancer stages for MPHOSPH8

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
ACCpathologic_stageCAediting_950674chr13_19672935_+0.0218257033830246-0.271852661722983
BLCApathologic_stageCAediting_950674chr13_19672935_+0.003271725583640270.147633118409045
BRCApathologic_stageCAediting_950654chr13_19672406_+0.01360436914705720.205936997251636
ESCAclinical_stageCAediting_950674chr13_19672935_+0.0258008850381111-0.306111279909399
HNSCclinical_stageCAediting_950665chr13_19672889_+0.02849046382025290.16108485135922
HNSCpathologic_stageCAediting_950674chr13_19672935_+0.02776333572611660.1082947370929
KIRCpathologic_stageCAediting_950674chr13_19672935_+1.09991705149365e-050.1903947849735
KIRCpathologic_stageCAediting_950678chr13_19672976_+0.0007995227486867530.148450718861109
KIRPclinical_stageCAediting_950678chr13_19672976_+1.33121309509287e-050.33782356036678
KIRPpathologic_stageCAediting_950678chr13_19672976_+5.09243872738895e-070.338348306314648
LUADpathologic_stageCAediting_950674chr13_19672935_+0.0309423041617450.0977967039735878
LUADpathologic_stageCAediting_950678chr13_19672976_+0.02723631587624570.102405132598072
LUSCpathologic_stageCAediting_950678chr13_19672976_+0.03502189291273450.099296918006712
PAADpathologic_stageCAediting_950674chr13_19672935_+0.003481031172576170.220354218717533
SKCMpathologic_stageCAediting_950665chr13_19672889_+0.01280659143938360.261448342203488
TGCTclinical_stageCAediting_950682chr13_19673001_+0.0290934724803318-0.380143008770416
THCApathologic_stageCAediting_950674chr13_19672935_+0.0172016878187220.106506117710875
THCApathologic_stageCAediting_950678chr13_19672976_+0.000175627492956570.172581750496786

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Relation with survival for MPHOSPH8

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LUADCAediting_950665chr13_19672889_+0.02885227166957930.00718212501.987
OVCAediting_950674chr13_19672935_+0.02811833024515740.005426144.27983

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RelatedDrugs for MPHOSPH8

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MPHOSPH8

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource