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Editing gene: POLR2H (CAeditome ID:5437)

Gene summary for POLR2H

Gene summary

Gene information	Gene symbol	POLR2H
	Gene ID	5437
	Gene name	RNA polymerase II, I and III subunit H
	Synonyms	RPABC3\|RPB17\|RPB8
	Cytomap	3q27.1
	Type of gene	protein-coding
	Description	DNA-directed RNA polymerases I, II, and III subunit RPABC3DNA-directed RNA polymerase II subunit HDNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptideRNA polymerase II subunit HRPB8 homologpolymerase (RNA) II (DNA directed) polypeptide H
	Modification date	20210518
	UniProtAcc	P52434
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
POLR2H	GO:0003697	DNA-directed RNA polymerases I, II, and III subunit RPABC3	16632472
POLR2H	GO:0006366	DNA-directed RNA polymerases I, II, and III subunit RPABC3	9852112
POLR2H	GO:0005634	DNA-directed RNA polymerases I, II, and III subunit RPABC3	9852112
POLR2H	GO:0005665	DNA-directed RNA polymerases I, II, and III subunit RPABC3	9852112
POLR2H	GO:0032993	DNA-directed RNA polymerases I, II, and III subunit RPABC3	16632472

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RNA A-to-I events for POLR2H

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000163882.8

RNA A-to-I editing events in Cancer.

CAediting_329492(184363835, +), CAediting_329493(184363850, +), CAediting_329494(184363855, +), CAediting_329495(184363864, +), CAediting_329496(184363865, +), CAediting_329497(184363867, +), CAediting_329498(184363873, +), CAediting_329499(184363874, +), CAediting_329500(184363875, +), CAediting_329501(184363886, +), CAediting_329502(184363889, +), CAediting_329503(184363890, +), CAediting_329504(184363891, +), CAediting_329505(184363892, +), CAediting_329506(184363893, +), CAediting_329507(184363895, +), CAediting_329508(184363904, +), CAediting_329509(184363930, +), CAediting_329510(184363931, +), CAediting_329511(184363940, +), CAediting_329512(184363953, +), CAediting_329513(184363972, +), CAediting_329514(184363985, +), CAediting_329515(184363992, +), CAediting_329516(184363996, +), CAediting_329517(184364000, +), CAediting_329518(184364001, +), CAediting_329519(184364003, +), CAediting_329520(184364011, +), CAediting_329521(184364021, +), CAediting_329522(184364249, +), CAediting_329523(184364251, +), CAediting_329524(184364273, +), CAediting_329525(184364280, +), CAediting_329526(184364291, +), CAediting_329527(184364299, +), CAediting_329528(184364304, +), CAediting_329529(184364307, +), CAediting_329530(184364309, +), CAediting_329531(184364310, +), CAediting_329532(184364329, +), CAediting_329533(184364330, +), CAediting_329534(184364346, +), CAediting_329535(184364355, +), CAediting_329536(184364358, +), CAediting_329537(184364368, +), CAediting_329538(184364402, +), CAediting_329539(184364408, +), CAediting_329540(184364411, +), CAediting_329541(184364417, +), CAediting_329542(184364449, +), CAediting_329543(184364464, +), CAediting_329544(184364490, +), CAediting_329545(184364502, +), CAediting_329546(184364508, +), CAediting_329547(184364659, +), CAediting_329548(184365399, +), CAediting_329549(184365405, +), CAediting_329550(184365406, +), CAediting_329551(184365411, +), CAediting_329552(184365451, +), CAediting_329553(184365460, +), CAediting_329554(184365471, +), CAediting_329555(184365475, +), CAediting_329556(184365479, +), CAediting_329557(184365496, +), CAediting_329558(184365498, +), CAediting_329559(184365499, +), CAediting_329560(184365501, +), CAediting_329561(184365505, +), CAediting_329562(184365506, +), CAediting_329563(184365508, +), CAediting_329564(184365510, +), CAediting_329565(184365520, +), CAediting_329566(184365532, +), CAediting_329567(184365550, +), CAediting_329568(184365567, +), CAediting_329569(184365573, +), CAediting_329570(184365591, +), CAediting_329571(184365612, +), CAediting_329572(184365620, +), CAediting_329573(184365628, +), CAediting_329574(184365653, +), CAediting_329575(184365659, +), CAediting_329576(184365679, +), CAediting_329577(184365681, +), CAediting_329578(184365992, +), CAediting_329579(184366407, +), CAediting_329580(184366418, +), CAediting_329581(184366455, +), CAediting_329582(184366467, +), CAediting_329583(184366537, +), CAediting_329584(184366600, +), CAediting_329585(184366612, +), CAediting_329586(184366961, +),

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RNA editing positional annotations for POLR2H using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_329492	chr3_184363835_+	intronic
CAediting_329493	chr3_184363850_+	intronic
CAediting_329494	chr3_184363855_+	intronic
CAediting_329495	chr3_184363864_+	intronic
CAediting_329496	chr3_184363865_+	intronic
CAediting_329497	chr3_184363867_+	intronic
CAediting_329498	chr3_184363873_+	intronic
CAediting_329499	chr3_184363874_+	intronic
CAediting_329500	chr3_184363875_+	intronic
CAediting_329501	chr3_184363886_+	intronic
CAediting_329502	chr3_184363889_+	intronic
CAediting_329503	chr3_184363890_+	intronic
CAediting_329504	chr3_184363891_+	intronic
CAediting_329505	chr3_184363892_+	intronic
CAediting_329506	chr3_184363893_+	intronic
CAediting_329507	chr3_184363895_+	intronic
CAediting_329508	chr3_184363904_+	intronic
CAediting_329509	chr3_184363930_+	intronic
CAediting_329510	chr3_184363931_+	intronic
CAediting_329511	chr3_184363940_+	intronic
CAediting_329512	chr3_184363953_+	intronic
CAediting_329513	chr3_184363972_+	intronic
CAediting_329514	chr3_184363985_+	intronic
CAediting_329515	chr3_184363992_+	intronic
CAediting_329516	chr3_184363996_+	intronic
CAediting_329517	chr3_184364000_+	intronic
CAediting_329518	chr3_184364001_+	intronic
CAediting_329519	chr3_184364003_+	intronic
CAediting_329520	chr3_184364011_+	intronic
CAediting_329521	chr3_184364021_+	intronic
CAediting_329522	chr3_184364249_+	intronic
CAediting_329523	chr3_184364251_+	intronic
CAediting_329524	chr3_184364273_+	intronic
CAediting_329525	chr3_184364280_+	intronic
CAediting_329526	chr3_184364291_+	intronic
CAediting_329527	chr3_184364299_+	intronic
CAediting_329528	chr3_184364304_+	intronic
CAediting_329529	chr3_184364307_+	intronic
CAediting_329530	chr3_184364309_+	intronic
CAediting_329531	chr3_184364310_+	intronic
CAediting_329532	chr3_184364329_+	intronic
CAediting_329533	chr3_184364330_+	intronic
CAediting_329534	chr3_184364346_+	intronic
CAediting_329535	chr3_184364355_+	intronic
CAediting_329536	chr3_184364358_+	intronic
CAediting_329537	chr3_184364368_+	intronic
CAediting_329538	chr3_184364402_+	intronic
CAediting_329539	chr3_184364408_+	intronic
CAediting_329540	chr3_184364411_+	intronic
CAediting_329541	chr3_184364417_+	intronic
CAediting_329542	chr3_184364449_+	intronic
CAediting_329543	chr3_184364464_+	ncRNA_exonic
CAediting_329544	chr3_184364490_+	ncRNA_exonic
CAediting_329545	chr3_184364502_+	ncRNA_exonic
CAediting_329546	chr3_184364508_+	ncRNA_exonic
CAediting_329547	chr3_184364659_+	ncRNA_exonic
CAediting_329548	chr3_184365399_+	ncRNA_exonic
CAediting_329549	chr3_184365405_+	ncRNA_exonic
CAediting_329550	chr3_184365406_+	ncRNA_exonic
CAediting_329551	chr3_184365411_+	ncRNA_exonic
CAediting_329552	chr3_184365451_+	ncRNA_exonic
CAediting_329553	chr3_184365460_+	ncRNA_exonic
CAediting_329554	chr3_184365471_+	ncRNA_exonic
CAediting_329555	chr3_184365475_+	ncRNA_exonic
CAediting_329556	chr3_184365479_+	ncRNA_exonic
CAediting_329557	chr3_184365496_+	ncRNA_exonic
CAediting_329558	chr3_184365498_+	ncRNA_exonic
CAediting_329559	chr3_184365499_+	ncRNA_exonic
CAediting_329560	chr3_184365501_+	ncRNA_exonic
CAediting_329561	chr3_184365505_+	ncRNA_exonic
CAediting_329562	chr3_184365506_+	ncRNA_exonic
CAediting_329563	chr3_184365508_+	ncRNA_exonic
CAediting_329564	chr3_184365510_+	ncRNA_exonic
CAediting_329565	chr3_184365520_+	ncRNA_exonic
CAediting_329566	chr3_184365532_+	ncRNA_intronic
CAediting_329567	chr3_184365550_+	ncRNA_intronic
CAediting_329568	chr3_184365567_+	ncRNA_intronic
CAediting_329569	chr3_184365573_+	ncRNA_intronic
CAediting_329570	chr3_184365591_+	ncRNA_intronic
CAediting_329571	chr3_184365612_+	ncRNA_intronic
CAediting_329572	chr3_184365620_+	ncRNA_intronic
CAediting_329573	chr3_184365628_+	ncRNA_intronic
CAediting_329574	chr3_184365653_+	ncRNA_intronic
CAediting_329575	chr3_184365659_+	ncRNA_intronic
CAediting_329576	chr3_184365679_+	ncRNA_intronic
CAediting_329577	chr3_184365681_+	ncRNA_intronic
CAediting_329578	chr3_184365992_+	ncRNA_intronic
CAediting_329579	chr3_184366407_+	ncRNA_intronic
CAediting_329580	chr3_184366418_+	ncRNA_intronic
CAediting_329581	chr3_184366455_+	ncRNA_intronic
CAediting_329582	chr3_184366467_+	ncRNA_intronic
CAediting_329583	chr3_184366537_+	ncRNA_exonic
CAediting_329584	chr3_184366600_+	ncRNA_exonic
CAediting_329585	chr3_184366612_+	ncRNA_exonic
CAediting_329586	chr3_184366961_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_329493	chr3_184363850_+	SINE	Alu	AluSx1
CAediting_329494	chr3_184363855_+	SINE	Alu	AluSx1
CAediting_329495	chr3_184363864_+	SINE	Alu	AluSx1
CAediting_329496	chr3_184363865_+	SINE	Alu	AluSx1
CAediting_329497	chr3_184363867_+	SINE	Alu	AluSx1
CAediting_329498	chr3_184363873_+	SINE	Alu	AluSx1
CAediting_329499	chr3_184363874_+	SINE	Alu	AluSx1
CAediting_329500	chr3_184363875_+	SINE	Alu	AluSx1
CAediting_329501	chr3_184363886_+	SINE	Alu	AluSx1
CAediting_329502	chr3_184363889_+	SINE	Alu	AluSx1
CAediting_329503	chr3_184363890_+	SINE	Alu	AluSx1
CAediting_329504	chr3_184363891_+	SINE	Alu	AluSx1
CAediting_329505	chr3_184363892_+	SINE	Alu	AluSx1
CAediting_329506	chr3_184363893_+	SINE	Alu	AluSx1
CAediting_329507	chr3_184363895_+	SINE	Alu	AluSx1
CAediting_329508	chr3_184363904_+	SINE	Alu	AluSx1
CAediting_329509	chr3_184363930_+	SINE	Alu	AluSx1
CAediting_329510	chr3_184363931_+	SINE	Alu	AluSx1
CAediting_329511	chr3_184363940_+	SINE	Alu	AluSx1
CAediting_329512	chr3_184363953_+	SINE	Alu	AluSx1
CAediting_329513	chr3_184363972_+	SINE	Alu	AluSx1
CAediting_329514	chr3_184363985_+	SINE	Alu	AluSx1
CAediting_329515	chr3_184363992_+	SINE	Alu	AluSx1
CAediting_329516	chr3_184363996_+	SINE	Alu	AluSx1
CAediting_329517	chr3_184364000_+	SINE	Alu	AluSx1
CAediting_329518	chr3_184364001_+	SINE	Alu	AluSx1
CAediting_329519	chr3_184364003_+	SINE	Alu	AluSx1
CAediting_329520	chr3_184364011_+	SINE	Alu	AluSx1
CAediting_329521	chr3_184364021_+	SINE	Alu	AluSx1
CAediting_329522	chr3_184364249_+	SINE	Alu	AluSz
CAediting_329523	chr3_184364251_+	SINE	Alu	AluSz
CAediting_329524	chr3_184364273_+	SINE	Alu	AluSz
CAediting_329525	chr3_184364280_+	SINE	Alu	AluSz
CAediting_329526	chr3_184364291_+	SINE	Alu	AluSz
CAediting_329527	chr3_184364299_+	SINE	Alu	AluSz
CAediting_329528	chr3_184364304_+	SINE	Alu	AluSz
CAediting_329529	chr3_184364307_+	SINE	Alu	AluSz
CAediting_329530	chr3_184364309_+	SINE	Alu	AluSz
CAediting_329531	chr3_184364310_+	SINE	Alu	AluSz
CAediting_329532	chr3_184364329_+	SINE	Alu	AluSz
CAediting_329533	chr3_184364330_+	SINE	Alu	AluSz
CAediting_329534	chr3_184364346_+	SINE	Alu	AluSz
CAediting_329535	chr3_184364355_+	SINE	Alu	AluSz
CAediting_329536	chr3_184364358_+	SINE	Alu	AluSz
CAediting_329537	chr3_184364368_+	SINE	Alu	AluSz
CAediting_329538	chr3_184364402_+	SINE	Alu	AluSz
CAediting_329539	chr3_184364408_+	SINE	Alu	AluSz
CAediting_329540	chr3_184364411_+	SINE	Alu	AluSz
CAediting_329541	chr3_184364417_+	SINE	Alu	AluSz
CAediting_329542	chr3_184364449_+	SINE	Alu	AluSz
CAediting_329543	chr3_184364464_+	SINE	Alu	AluSz
CAediting_329544	chr3_184364490_+	SINE	Alu	AluSz
CAediting_329545	chr3_184364502_+	SINE	Alu	AluSz
CAediting_329546	chr3_184364508_+	SINE	Alu	AluSz
CAediting_329548	chr3_184365399_+	SINE	Alu	AluJb
CAediting_329549	chr3_184365405_+	SINE	Alu	AluJb
CAediting_329550	chr3_184365406_+	SINE	Alu	AluJb
CAediting_329551	chr3_184365411_+	SINE	Alu	AluJb
CAediting_329552	chr3_184365451_+	SINE	Alu	AluJb
CAediting_329553	chr3_184365460_+	SINE	Alu	AluJb
CAediting_329554	chr3_184365471_+	SINE	Alu	AluJb
CAediting_329555	chr3_184365475_+	SINE	Alu	AluJb
CAediting_329556	chr3_184365479_+	SINE	Alu	AluJb
CAediting_329557	chr3_184365496_+	SINE	Alu	AluJb
CAediting_329558	chr3_184365498_+	SINE	Alu	AluJb
CAediting_329559	chr3_184365499_+	SINE	Alu	AluJb
CAediting_329560	chr3_184365501_+	SINE	Alu	AluJb
CAediting_329561	chr3_184365505_+	SINE	Alu	AluJb
CAediting_329562	chr3_184365506_+	SINE	Alu	AluJb
CAediting_329563	chr3_184365508_+	SINE	Alu	AluJb
CAediting_329564	chr3_184365510_+	SINE	Alu	AluJb
CAediting_329565	chr3_184365520_+	SINE	Alu	AluJb
CAediting_329566	chr3_184365532_+	SINE	Alu	AluJb
CAediting_329567	chr3_184365550_+	SINE	Alu	AluJb
CAediting_329568	chr3_184365567_+	SINE	Alu	AluJb
CAediting_329569	chr3_184365573_+	SINE	Alu	AluJb
CAediting_329570	chr3_184365591_+	SINE	Alu	AluJb
CAediting_329571	chr3_184365612_+	SINE	Alu	AluJb
CAediting_329572	chr3_184365620_+	SINE	Alu	AluJb
CAediting_329573	chr3_184365628_+	SINE	Alu	AluJb
CAediting_329574	chr3_184365653_+	SINE	Alu	AluJb
CAediting_329575	chr3_184365659_+	SINE	Alu	AluJb
CAediting_329576	chr3_184365679_+	SINE	Alu	AluJb
CAediting_329577	chr3_184365681_+	SINE	Alu	AluJb
CAediting_329578	chr3_184365992_+	SINE	Alu	AluYa5
CAediting_329579	chr3_184366407_+	SINE	Alu	AluYm1
CAediting_329580	chr3_184366418_+	SINE	Alu	AluYm1
CAediting_329581	chr3_184366455_+	SINE	Alu	AluYm1
CAediting_329582	chr3_184366467_+	SINE	Alu	AluYm1
CAediting_329583	chr3_184366537_+	SINE	Alu	AluYm1
CAediting_329584	chr3_184366600_+	SINE	Alu	AluYm1
CAediting_329585	chr3_184366612_+	SINE	Alu	AluYm1

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RNA A-to-I editing events in the alternative splicing sites for POLR2H

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000163882.8.POLR2H.

Correlation between RNA A-to-I editing and PSI for ENSG00000163882.8.POLR2H.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for POLR2H

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for POLR2H

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for POLR2H

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for POLR2H

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000488213.4	retained_intron
ENST00000490958.1	retained_intron
ENST00000476003.1	retained_intron

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_329543	ENST00000488213.4	chr3_184364464_+	-321.30	-321.30	-329.40
CAediting_329544	ENST00000488213.4	chr3_184364490_+	-321.90	-321.30	-329.40
CAediting_329545	ENST00000488213.4	chr3_184364502_+	-324.30	-321.30	-329.40
CAediting_329546	ENST00000488213.4	chr3_184364508_+	-322.50	-321.30	-329.40
CAediting_329547	ENST00000488213.4	chr3_184364659_+	-324.60	-321.30	-329.40
CAediting_329548	ENST00000490958.1	chr3_184365399_+	-112.90	-109.40	-120.80
CAediting_329549	ENST00000490958.1	chr3_184365405_+	-110.80	-109.40	-120.80
CAediting_329550	ENST00000490958.1	chr3_184365406_+	-109.60	-109.40	-120.80
CAediting_329551	ENST00000490958.1	chr3_184365411_+	-110.60	-109.40	-120.80
CAediting_329552	ENST00000490958.1	chr3_184365451_+	-108.70	-109.40	-120.80
CAediting_329553	ENST00000490958.1	chr3_184365460_+	-109.90	-109.40	-120.80
CAediting_329554	ENST00000490958.1	chr3_184365471_+	-110.90	-109.40	-120.80
CAediting_329555	ENST00000490958.1	chr3_184365475_+	-109.40	-109.40	-120.80
CAediting_329556	ENST00000490958.1	chr3_184365479_+	-108.80	-109.40	-120.80
CAediting_329557	ENST00000490958.1	chr3_184365496_+	-109.40	-109.40	-120.80
CAediting_329558	ENST00000490958.1	chr3_184365498_+	-109.10	-109.40	-120.80
CAediting_329559	ENST00000490958.1	chr3_184365499_+	-110.40	-109.40	-120.80
CAediting_329560	ENST00000490958.1	chr3_184365501_+	-110.20	-109.40	-120.80
CAediting_329561	ENST00000490958.1	chr3_184365505_+	-109.90	-109.40	-120.80
CAediting_329562	ENST00000490958.1	chr3_184365506_+	-110.60	-109.40	-120.80
CAediting_329563	ENST00000490958.1	chr3_184365508_+	-108.50	-109.40	-120.80
CAediting_329564	ENST00000490958.1	chr3_184365510_+	-109.60	-109.40	-120.80
CAediting_329565	ENST00000490958.1	chr3_184365520_+	-109.40	-109.40	-120.80
CAediting_329583	ENST00000476003.1	chr3_184366537_+	-209.80	-209.50	-215.90
CAediting_329584	ENST00000476003.1	chr3_184366600_+	-216.10	-209.50	-215.90
CAediting_329585	ENST00000476003.1	chr3_184366612_+	-210.90	-209.50	-215.90

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Relation with ADAR for POLR2H

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LUSC	CAediting_329515	chr3_184363992_+	0.000371316999658824	0.367160146545801	.	.	.	.
LUSC	CAediting_329526	chr3_184364291_+	0.0115441332229118	0.326740076441772	.	.	.	.
LUSC	CAediting_329551	chr3_184365411_+	0.004979986374919	0.339238262449119	.	.	.	.

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Relation with cancer stages for POLR2H

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_329547	chr3_184364659_+	0.0342512586013034	0.21634374613466
LUSC	pathologic_stage	CAediting_329547	chr3_184364659_+	0.0499219805271737	0.278801772803601

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Relation with survival for POLR2H

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for POLR2H

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for POLR2H

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene