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Editing gene: RIPPLY3 (CAeditome ID:53820)

Gene summary for RIPPLY3

Gene summary

Gene information	Gene symbol	RIPPLY3
	Gene ID	53820
	Gene name	ripply transcriptional repressor 3
	Synonyms	DSCR6
	Cytomap	21q22.13
	Type of gene	protein-coding
	Description	protein ripply3Down syndrome critical region gene 6down syndrome critical region protein 6ripply3 homolog
	Modification date	20210518
	UniProtAcc	P57055
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for RIPPLY3

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000183145.7

RNA A-to-I editing events in Cancer.

CAediting_1452003(37010478, +), CAediting_1452004(37018713, +), CAediting_1452005(37018717, +), CAediting_1452006(37018748, +), CAediting_1452007(37018752, +), CAediting_1452008(37018754, +), CAediting_1452009(37018756, +), CAediting_1452010(37018767, +), CAediting_1452011(37018772, +), CAediting_1452012(37018779, +), CAediting_1452013(37018792, +), CAediting_1452014(37018797, +), CAediting_1452015(37018810, +), CAediting_1452016(37018818, +), CAediting_1452017(37018819, +), CAediting_1452018(37018822, +), CAediting_1452019(37018832, +), CAediting_1452020(37018834, +), CAediting_1452021(37018838, +), CAediting_1452022(37018841, +), CAediting_1452023(37018848, +), CAediting_1452024(37018858, +), CAediting_1452025(37018859, +), CAediting_1452026(37018868, +), CAediting_1452027(37018874, +), CAediting_1452028(37018877, +), CAediting_1452029(37018891, +), CAediting_1452030(37018903, +), CAediting_1452031(37018955, +), CAediting_1452032(37018956, +), CAediting_1452033(37018968, +), CAediting_1452034(37019075, +), CAediting_1452035(37019078, +), CAediting_1452036(37019079, +), CAediting_1452037(37019085, +), CAediting_1452038(37019088, +), CAediting_1452039(37019089, +), CAediting_1452040(37019100, +), CAediting_1452041(37019103, +), CAediting_1452042(37019104, +), CAediting_1452043(37019105, +), CAediting_1452044(37019106, +), CAediting_1452045(37019107, +), CAediting_1452046(37019109, +), CAediting_1452047(37019112, +), CAediting_1452048(37019113, +), CAediting_1452049(37019117, +), CAediting_1452050(37019121, +), CAediting_1452051(37019128, +), CAediting_1452052(37019135, +), CAediting_1452053(37019143, +), CAediting_1452054(37019149, +), CAediting_1452055(37019153, +), CAediting_1452056(37019170, +), CAediting_1452057(37019173, +), CAediting_1452058(37019176, +), CAediting_1452059(37019182, +), CAediting_1452060(37019185, +), CAediting_1452061(37019209, +), CAediting_1452062(37019214, +), CAediting_1452063(37019216, +), CAediting_1452064(37019234, +), CAediting_1452065(37019243, +), CAediting_1452066(37019246, +), CAediting_1452067(37019247, +),

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RNA editing positional annotations for RIPPLY3 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1452003	chr21_37010478_+	ncRNA_intronic
CAediting_1452004	chr21_37018713_+	ncRNA_exonic
CAediting_1452005	chr21_37018717_+	ncRNA_exonic
CAediting_1452006	chr21_37018748_+	ncRNA_exonic
CAediting_1452007	chr21_37018752_+	ncRNA_exonic
CAediting_1452008	chr21_37018754_+	ncRNA_exonic
CAediting_1452009	chr21_37018756_+	ncRNA_exonic
CAediting_1452010	chr21_37018767_+	ncRNA_exonic
CAediting_1452011	chr21_37018772_+	ncRNA_exonic
CAediting_1452012	chr21_37018779_+	ncRNA_exonic
CAediting_1452013	chr21_37018792_+	ncRNA_exonic
CAediting_1452014	chr21_37018797_+	ncRNA_exonic
CAediting_1452015	chr21_37018810_+	ncRNA_exonic
CAediting_1452016	chr21_37018818_+	ncRNA_exonic
CAediting_1452017	chr21_37018819_+	ncRNA_exonic
CAediting_1452018	chr21_37018822_+	ncRNA_exonic
CAediting_1452019	chr21_37018832_+	ncRNA_exonic
CAediting_1452020	chr21_37018834_+	ncRNA_exonic
CAediting_1452021	chr21_37018838_+	ncRNA_exonic
CAediting_1452022	chr21_37018841_+	ncRNA_exonic
CAediting_1452023	chr21_37018848_+	ncRNA_exonic
CAediting_1452024	chr21_37018858_+	ncRNA_exonic
CAediting_1452025	chr21_37018859_+	ncRNA_exonic
CAediting_1452026	chr21_37018868_+	ncRNA_exonic
CAediting_1452027	chr21_37018874_+	ncRNA_exonic
CAediting_1452028	chr21_37018877_+	ncRNA_exonic
CAediting_1452029	chr21_37018891_+	ncRNA_exonic
CAediting_1452030	chr21_37018903_+	ncRNA_exonic
CAediting_1452031	chr21_37018955_+	ncRNA_exonic
CAediting_1452032	chr21_37018956_+	ncRNA_exonic
CAediting_1452033	chr21_37018968_+	ncRNA_exonic
CAediting_1452034	chr21_37019075_+	ncRNA_exonic
CAediting_1452035	chr21_37019078_+	ncRNA_exonic
CAediting_1452036	chr21_37019079_+	ncRNA_exonic
CAediting_1452037	chr21_37019085_+	ncRNA_exonic
CAediting_1452038	chr21_37019088_+	ncRNA_exonic
CAediting_1452039	chr21_37019089_+	ncRNA_exonic
CAediting_1452040	chr21_37019100_+	ncRNA_exonic
CAediting_1452041	chr21_37019103_+	ncRNA_exonic
CAediting_1452042	chr21_37019104_+	ncRNA_exonic
CAediting_1452043	chr21_37019105_+	ncRNA_exonic
CAediting_1452044	chr21_37019106_+	ncRNA_exonic
CAediting_1452045	chr21_37019107_+	ncRNA_exonic
CAediting_1452046	chr21_37019109_+	ncRNA_exonic
CAediting_1452047	chr21_37019112_+	ncRNA_exonic
CAediting_1452048	chr21_37019113_+	ncRNA_exonic
CAediting_1452049	chr21_37019117_+	ncRNA_exonic
CAediting_1452050	chr21_37019121_+	ncRNA_exonic
CAediting_1452051	chr21_37019128_+	ncRNA_exonic
CAediting_1452052	chr21_37019135_+	ncRNA_exonic
CAediting_1452053	chr21_37019143_+	ncRNA_exonic
CAediting_1452054	chr21_37019149_+	ncRNA_exonic
CAediting_1452055	chr21_37019153_+	ncRNA_exonic
CAediting_1452056	chr21_37019170_+	ncRNA_exonic
CAediting_1452057	chr21_37019173_+	ncRNA_exonic
CAediting_1452058	chr21_37019176_+	ncRNA_exonic
CAediting_1452059	chr21_37019182_+	ncRNA_exonic
CAediting_1452060	chr21_37019185_+	ncRNA_exonic
CAediting_1452061	chr21_37019209_+	ncRNA_exonic
CAediting_1452062	chr21_37019214_+	ncRNA_exonic
CAediting_1452063	chr21_37019216_+	ncRNA_exonic
CAediting_1452064	chr21_37019234_+	ncRNA_exonic
CAediting_1452065	chr21_37019243_+	ncRNA_exonic
CAediting_1452066	chr21_37019246_+	ncRNA_exonic
CAediting_1452067	chr21_37019247_+	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1452003	chr21_37010478_+	SINE	Alu	AluSx
CAediting_1452004	chr21_37018713_+	SINE	Alu	AluSq2
CAediting_1452005	chr21_37018717_+	SINE	Alu	AluSq2
CAediting_1452006	chr21_37018748_+	SINE	Alu	AluSq2
CAediting_1452007	chr21_37018752_+	SINE	Alu	AluSq2
CAediting_1452008	chr21_37018754_+	SINE	Alu	AluSq2
CAediting_1452009	chr21_37018756_+	SINE	Alu	AluSq2
CAediting_1452010	chr21_37018767_+	SINE	Alu	AluSq2
CAediting_1452011	chr21_37018772_+	SINE	Alu	AluSq2
CAediting_1452012	chr21_37018779_+	SINE	Alu	AluSq2
CAediting_1452013	chr21_37018792_+	SINE	Alu	AluSq2
CAediting_1452014	chr21_37018797_+	SINE	Alu	AluSq2
CAediting_1452015	chr21_37018810_+	SINE	Alu	AluSq2
CAediting_1452016	chr21_37018818_+	SINE	Alu	AluSq2
CAediting_1452017	chr21_37018819_+	SINE	Alu	AluSq2
CAediting_1452018	chr21_37018822_+	SINE	Alu	AluSq2
CAediting_1452019	chr21_37018832_+	SINE	Alu	AluSq2
CAediting_1452020	chr21_37018834_+	SINE	Alu	AluSq2
CAediting_1452021	chr21_37018838_+	SINE	Alu	AluSq2
CAediting_1452022	chr21_37018841_+	SINE	Alu	AluSq2
CAediting_1452023	chr21_37018848_+	SINE	Alu	AluSq2
CAediting_1452024	chr21_37018858_+	SINE	Alu	AluSq2
CAediting_1452025	chr21_37018859_+	SINE	Alu	AluSq2
CAediting_1452026	chr21_37018868_+	SINE	Alu	AluSq2
CAediting_1452027	chr21_37018874_+	SINE	Alu	AluSq2
CAediting_1452028	chr21_37018877_+	SINE	Alu	AluSq2
CAediting_1452029	chr21_37018891_+	SINE	Alu	AluSq2
CAediting_1452030	chr21_37018903_+	SINE	Alu	AluSq2
CAediting_1452031	chr21_37018955_+	SINE	Alu	AluSq2
CAediting_1452032	chr21_37018956_+	SINE	Alu	AluSq2
CAediting_1452033	chr21_37018968_+	SINE	Alu	AluSq2
CAediting_1452034	chr21_37019075_+	SINE	Alu	AluSp
CAediting_1452035	chr21_37019078_+	SINE	Alu	AluSp
CAediting_1452036	chr21_37019079_+	SINE	Alu	AluSp
CAediting_1452037	chr21_37019085_+	SINE	Alu	AluSp
CAediting_1452038	chr21_37019088_+	SINE	Alu	AluSp
CAediting_1452039	chr21_37019089_+	SINE	Alu	AluSp
CAediting_1452040	chr21_37019100_+	SINE	Alu	AluSp
CAediting_1452041	chr21_37019103_+	SINE	Alu	AluSp
CAediting_1452042	chr21_37019104_+	SINE	Alu	AluSp
CAediting_1452043	chr21_37019105_+	SINE	Alu	AluSp
CAediting_1452044	chr21_37019106_+	SINE	Alu	AluSp
CAediting_1452045	chr21_37019107_+	SINE	Alu	AluSp
CAediting_1452046	chr21_37019109_+	SINE	Alu	AluSp
CAediting_1452047	chr21_37019112_+	SINE	Alu	AluSp
CAediting_1452048	chr21_37019113_+	SINE	Alu	AluSp
CAediting_1452049	chr21_37019117_+	SINE	Alu	AluSp
CAediting_1452050	chr21_37019121_+	SINE	Alu	AluSp
CAediting_1452051	chr21_37019128_+	SINE	Alu	AluSp
CAediting_1452052	chr21_37019135_+	SINE	Alu	AluSp
CAediting_1452053	chr21_37019143_+	SINE	Alu	AluSp
CAediting_1452054	chr21_37019149_+	SINE	Alu	AluSp
CAediting_1452055	chr21_37019153_+	SINE	Alu	AluSp
CAediting_1452056	chr21_37019170_+	SINE	Alu	AluSp
CAediting_1452057	chr21_37019173_+	SINE	Alu	AluSp
CAediting_1452058	chr21_37019176_+	SINE	Alu	AluSp
CAediting_1452059	chr21_37019182_+	SINE	Alu	AluSp
CAediting_1452060	chr21_37019185_+	SINE	Alu	AluSp
CAediting_1452061	chr21_37019209_+	SINE	Alu	AluSp
CAediting_1452062	chr21_37019214_+	SINE	Alu	AluSp
CAediting_1452063	chr21_37019216_+	SINE	Alu	AluSp
CAediting_1452064	chr21_37019234_+	SINE	Alu	AluSp
CAediting_1452065	chr21_37019243_+	SINE	Alu	AluSp
CAediting_1452066	chr21_37019246_+	SINE	Alu	AluSp
CAediting_1452067	chr21_37019247_+	SINE	Alu	AluSp

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RNA A-to-I editing events in the alternative splicing sites for RIPPLY3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000183145.7.RIPPLY3.

Correlation between RNA A-to-I editing and PSI for ENSG00000183145.7.RIPPLY3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RIPPLY3

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BLCA.CAediting_1452053.ENSG00000183145.RIPPLY3.png
Soverview

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Protein coding region RNA A-to-I editings for RIPPLY3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for RIPPLY3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RIPPLY3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for RIPPLY3

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BLCA	CAediting_1452004	chr21_37018713_+	0.0314725646266679	0.198161209126775	.	.	.	.
CESC	CAediting_1452004	chr21_37018713_+	0.00539494483849427	0.256778652435084	.	.	.	.
UCEC	CAediting_1452004	chr21_37018713_+	0.00273224356389669	0.312270660074195	.	.	.	.
BLCA	CAediting_1452005	chr21_37018717_+	.	.	0.000637162669533423	0.33416830647841	.	.
UCEC	CAediting_1452005	chr21_37018717_+	0.00768421105813776	0.283984557886575	.	.	.	.
BRCA	CAediting_1452008	chr21_37018754_+	0.00673822259293369	0.306327239925322	.	.	.	.
BLCA	CAediting_1452009	chr21_37018756_+	4.83972383284222e-05	0.419024027238274	.	.	.	.
BRCA	CAediting_1452009	chr21_37018756_+	8.26152719106077e-07	0.34433846096102	.	.	.	.
CESC	CAediting_1452009	chr21_37018756_+	0.0175911812796413	0.283028342911814	.	.	.	.
LUSC	CAediting_1452009	chr21_37018756_+	.	.	.	.	0.0405119952407918	0.285079922702987
UCEC	CAediting_1452009	chr21_37018756_+	8.80036270184082e-06	0.474324060764141	.	.	.	.
BLCA	CAediting_1452016	chr21_37018818_+	1.32529685028817e-07	0.475619528829308	.	.	.	.
BRCA	CAediting_1452016	chr21_37018818_+	0.00126477028296612	0.310517907631306	.	.	.	.
CESC	CAediting_1452016	chr21_37018818_+	0.0144557820743115	0.295413711362065	.	.	.	.
STAD	CAediting_1452016	chr21_37018818_+	0.00240585379556532	0.41980244430073	.	.	.	.
UCEC	CAediting_1452016	chr21_37018818_+	0.000369063092660463	0.345929728442002	0.0201676778319324	0.229777367921578	.	.
BLCA	CAediting_1452018	chr21_37018822_+	6.25492609028729e-05	0.37702923493775	.	.	.	.
BRCA	CAediting_1452018	chr21_37018822_+	4.84126758519596e-06	0.435237737408937	.	.	.	.
CESC	CAediting_1452018	chr21_37018822_+	0.0250998784763268	0.275610313948264	.	.	.	.
UCEC	CAediting_1452018	chr21_37018822_+	0.00147590609517807	0.305031020318643	.	.	.	.
BLCA	CAediting_1452019	chr21_37018832_+	1.93565388250516e-09	0.51021299807126	.	.	.	.
BRCA	CAediting_1452019	chr21_37018832_+	0.00118955179238287	0.302466997070239	.	.	.	.
CESC	CAediting_1452019	chr21_37018832_+	0.000644409149953889	0.385158212033547	.	.	.	.
UCEC	CAediting_1452019	chr21_37018832_+	0.000214366625678035	0.358647706878112	.	.	.	.
BLCA	CAediting_1452027	chr21_37018874_+	0.0209659365607926	0.261061432581139	0.030780817376775	0.244778405804823	.	.
BRCA	CAediting_1452027	chr21_37018874_+	1.76099662135191e-06	0.403522377257306	0.0420709170548175	0.177893831555589	.	.
CESC	CAediting_1452027	chr21_37018874_+	3.11957120471192e-05	0.495666531247491	.	.	.	.
UCEC	CAediting_1452027	chr21_37018874_+	0.000124951600108042	0.486404775725314	.	.	.	.
BLCA	CAediting_1452028	chr21_37018877_+	.	.	0.0445959444794574	0.232630349681164	.	.
BRCA	CAediting_1452028	chr21_37018877_+	0.000338903280714719	0.311869222755119	.	.	.	.
CESC	CAediting_1452028	chr21_37018877_+	0.00929576305135846	0.338737818489972	.	.	.	.
UCEC	CAediting_1452028	chr21_37018877_+	0.00011221728132373	0.474407492084166	.	.	.	.
BLCA	CAediting_1452035	chr21_37019078_+	0.0122417170882435	0.329775189157348	.	.	.	.
BRCA	CAediting_1452035	chr21_37019078_+	2.79419026173406e-06	0.393477971008928	.	.	.	.
BLCA	CAediting_1452036	chr21_37019079_+	1.62245783519698e-12	0.514161329683124	.	.	.	.
BRCA	CAediting_1452036	chr21_37019079_+	5.40688760394742e-20	0.477120996655669	.	.	.	.
CESC	CAediting_1452036	chr21_37019079_+	2.01205460662318e-06	0.401447830136892	.	.	.	.
LUAD	CAediting_1452036	chr21_37019079_+	0.00090579611523226	0.401877669499343	.	.	.	.
PRAD	CAediting_1452036	chr21_37019079_+	6.09679029545166e-05	0.482964800843273	.	.	.	.
UCEC	CAediting_1452036	chr21_37019079_+	3.79364113293454e-08	0.444388354022407	.	.	.	.
BLCA	CAediting_1452041	chr21_37019103_+	0.0453521122294687	0.259391880618842	.	.	.	.
BRCA	CAediting_1452041	chr21_37019103_+	2.18298259955294e-05	0.414686954781535	.	.	.	.
UCEC	CAediting_1452041	chr21_37019103_+	0.000773695681182391	0.44387546847567	.	.	.	.
BRCA	CAediting_1452042	chr21_37019104_+	0.00137568953799744	0.407074800252758	.	.	.	.
BLCA	CAediting_1452046	chr21_37019109_+	9.35797470718534e-06	0.493035603616696	.	.	.	.
BRCA	CAediting_1452046	chr21_37019109_+	1.39434335830385e-07	0.518615415038122	.	.	.	.
CESC	CAediting_1452046	chr21_37019109_+	0.013012073639427	0.348921225407871	.	.	.	.
UCEC	CAediting_1452046	chr21_37019109_+	0.000114797033003675	0.413086053989747	0.00891269745064942	0.287120216352723	.	.
BLCA	CAediting_1452049	chr21_37019117_+	2.7473402406284e-05	0.445439642242961	.	.	.	.
BRCA	CAediting_1452049	chr21_37019117_+	0.000550850876845842	0.331527797889808	.	.	.	.
CESC	CAediting_1452049	chr21_37019117_+	0.00010870868438253	0.471719406370812	.	.	.	.
UCEC	CAediting_1452049	chr21_37019117_+	2.23397843681669e-05	0.40656177985117	.	.	.	.
BLCA	CAediting_1452053	chr21_37019143_+	9.48918401851254e-05	0.458642774834747	0.0315972662436286	0.262908386986029	.	.
BRCA	CAediting_1452053	chr21_37019143_+	0.00255698942522639	0.355106970732894	.	.	.	.
UCEC	CAediting_1452053	chr21_37019143_+	5.97915872296455e-05	0.395875288303719	0.0174297243014531	0.240955510842525	.	.
BLCA	CAediting_1452059	chr21_37019182_+	3.29879067948841e-05	0.338654540026107	.	.	.	.
BRCA	CAediting_1452059	chr21_37019182_+	2.42720142262524e-06	0.38247905860729	.	.	.	.
CESC	CAediting_1452059	chr21_37019182_+	0.00354215245726824	0.290441416249101	.	.	.	.
UCEC	CAediting_1452059	chr21_37019182_+	0.000667670821670536	0.276555113941385	0.0101340241310092	0.210760619520257	.	.
BLCA	CAediting_1452060	chr21_37019185_+	1.49421364341307e-05	0.39499170942243	0.0472234660563305	0.187094828454388	.	.
BRCA	CAediting_1452060	chr21_37019185_+	0.000280203247755115	0.323358413050219	.	.	.	.
UCEC	CAediting_1452060	chr21_37019185_+	1.88297791844208e-05	0.381296743281885	.	.	.	.
BLCA	CAediting_1452067	chr21_37019247_+	1.71090277799037e-11	0.569437358541426	.	.	.	.
BRCA	CAediting_1452067	chr21_37019247_+	1.1744529102092e-12	0.49176403551984	.	.	.	.
CESC	CAediting_1452067	chr21_37019247_+	0.000986222492088759	0.322995363634144	.	.	0.0429488757918617	0.201850340955167
LUSC	CAediting_1452067	chr21_37019247_+	0.000360868694798948	0.4678402836899	.	.	.	.
UCEC	CAediting_1452067	chr21_37019247_+	4.13053665234674e-08	0.482532598075394	.	.	.	.

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Relation with cancer stages for RIPPLY3

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_1452004	chr21_37018713_+	0.0117493882742141	0.1506579347771
BRCA	pathologic_stage	CAediting_1452009	chr21_37018756_+	0.00487300037791632	0.201354411979028
BRCA	pathologic_stage	CAediting_1452013	chr21_37018792_+	0.0394313095552875	-0.23839211368463
BRCA	pathologic_stage	CAediting_1452015	chr21_37018810_+	0.0383312474807901	0.261633305987866
BRCA	pathologic_stage	CAediting_1452016	chr21_37018818_+	0.00872884321920904	0.257179029603985
BRCA	pathologic_stage	CAediting_1452028	chr21_37018877_+	0.0472721103276552	0.176399719295636

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Relation with survival for RIPPLY3

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
CESC	CAediting_1452005	chr21_37018717_+	0.0245862066873889	0.00744082	64919.2
UCEC	CAediting_1452017	chr21_37018819_+	0.0370724637477517	0.0418052	9502470

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RelatedDrugs for RIPPLY3

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for RIPPLY3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene