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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: PMS1 (CAeditome ID:5378)

Gene summary for PMS1

check button Gene summary
Gene informationGene symbol

PMS1

Gene ID

5378

Gene namePMS1 homolog 1, mismatch repair system component
SynonymsHNPCC3|MLH2|PMSL1|hPMS1
Cytomap

2q32.2

Type of geneprotein-coding
DescriptionPMS1 protein homolog 1DNA mismatch repair protein PMS1PMS1 postmeiotic segregation increased 1human homolog of yeast mutLmismatch repair gene PMSL1rhabdomyosarcoma antigen MU-RMS-40.10Brhabdomyosarcoma antigen MU-RMS-40.10E
Modification date20210518
UniProtAcc

P54277

Context- 30590005(Associations of Genetic Variations in Mismatch Repair Genes MSH3 and PMS1 with Acute Adverse Events and Survival in Patients with Rectal Cancer Receiving Postoperative Chemoradiotherapy)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
PMS1

GO:0005634

PMS1 protein homolog 1

26300262


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RNA A-to-I events for PMS1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000064933.15

check button RNA A-to-I editing events in Cancer.
CAediting_229245(189787700, +), CAediting_229246(189787717, +), CAediting_229247(189787718, +), CAediting_229248(189787721, +), CAediting_229249(189787742, +), CAediting_229250(189787749, +), CAediting_229251(189787752, +), CAediting_229252(189787755, +), CAediting_229253(189787761, +), CAediting_229254(189787774, +), CAediting_229255(189787788, +), CAediting_229256(189787790, +), CAediting_229257(189787798, +), CAediting_229258(189788429, +), CAediting_229259(189788503, +), CAediting_229260(189788515, +), CAediting_229261(189788520, +), CAediting_229262(189788521, +), CAediting_229263(189788523, +), CAediting_229264(189788527, +), CAediting_229265(189788528, +), CAediting_229266(189788531, +), CAediting_229267(189788557, +), CAediting_229268(189788558, +), CAediting_229269(189806497, +), CAediting_229270(189806578, +), CAediting_229271(189806587, +), CAediting_229272(189809643, +), CAediting_229273(189820524, +), CAediting_229274(189820911, +), CAediting_229275(189821195, +), CAediting_229276(189821290, +), CAediting_229277(189821293, +), CAediting_229278(189821294, +), CAediting_229279(189821296, +), CAediting_229280(189821334, +), CAediting_229281(189821407, +), CAediting_229282(189827585, +), CAediting_229283(189827586, +), CAediting_229284(189827587, +), CAediting_229285(189827647, +), CAediting_229286(189827665, +), CAediting_229287(189827666, +), CAediting_229288(189827676, +), CAediting_229289(189827677, +), CAediting_229290(189827678, +), CAediting_229291(189834913, +), CAediting_229292(189834915, +), CAediting_229293(189835664, +), CAediting_229294(189835670, +), CAediting_229295(189835692, +), CAediting_229296(189835693, +), CAediting_229297(189835725, +), CAediting_229298(189835735, +), CAediting_229299(189835736, +), CAediting_229300(189835749, +), CAediting_229301(189835776, +), CAediting_229302(189835777, +), CAediting_229303(189835778, +), CAediting_229304(189835781, +), CAediting_229305(189835794, +), CAediting_229306(189835813, +), CAediting_229307(189835834, +), CAediting_229308(189844434, +), CAediting_229309(189844497, +), CAediting_229310(189844540, +), CAediting_229311(189844545, +), CAediting_229312(189844546, +), CAediting_229313(189844564, +), CAediting_229314(189844927, +), CAediting_229315(189844935, +), CAediting_229316(189844975, +), CAediting_229317(189844991, +), CAediting_229318(189845019, +), CAediting_229319(189845110, +), CAediting_229320(189845120, +), CAediting_229321(189847045, +), CAediting_229322(189847059, +), CAediting_229323(189861579, +), CAediting_229324(189863318, +), CAediting_229325(189863354, +), CAediting_229326(189863358, +), CAediting_229327(189863437, +), CAediting_229328(189863468, +), CAediting_229329(189863506, +), CAediting_229330(189864470, +), CAediting_229331(189864472, +), CAediting_229332(189864474, +), CAediting_229333(189864479, +), CAediting_229334(189864480, +), CAediting_229335(189864491, +), CAediting_229336(189864509, +), CAediting_229337(189864525, +), CAediting_229338(189864535, +), CAediting_229339(189864606, +), CAediting_229340(189864638, +), CAediting_229341(189872702, +), CAediting_229342(189872745, +), CAediting_229343(189872750, +), CAediting_229344(189872759, +), CAediting_229345(189872762, +), CAediting_229346(189872772, +), CAediting_229347(189872774, +), CAediting_229348(189872896, +),

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RNA editing positional annotations for PMS1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_229269chr2_189806497_+nonsynonymous SNVENST00000374826.7c.A493Gp.K165ED.N

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_229245chr2_189787700_+ncRNA_intronic
CAediting_229246chr2_189787717_+ncRNA_intronic
CAediting_229247chr2_189787718_+ncRNA_intronic
CAediting_229248chr2_189787721_+ncRNA_intronic
CAediting_229249chr2_189787742_+ncRNA_intronic
CAediting_229250chr2_189787749_+ncRNA_intronic
CAediting_229251chr2_189787752_+ncRNA_intronic
CAediting_229252chr2_189787755_+ncRNA_intronic
CAediting_229253chr2_189787761_+ncRNA_intronic
CAediting_229254chr2_189787774_+ncRNA_intronic
CAediting_229255chr2_189787788_+ncRNA_intronic
CAediting_229256chr2_189787790_+ncRNA_intronic
CAediting_229257chr2_189787798_+ncRNA_intronic
CAediting_229258chr2_189788429_+ncRNA_intronic
CAediting_229259chr2_189788503_+ncRNA_intronic
CAediting_229260chr2_189788515_+ncRNA_intronic
CAediting_229261chr2_189788520_+ncRNA_intronic
CAediting_229262chr2_189788521_+ncRNA_intronic
CAediting_229263chr2_189788523_+ncRNA_intronic
CAediting_229264chr2_189788527_+ncRNA_intronic
CAediting_229265chr2_189788528_+ncRNA_intronic
CAediting_229266chr2_189788531_+ncRNA_intronic
CAediting_229267chr2_189788557_+ncRNA_intronic
CAediting_229268chr2_189788558_+ncRNA_intronic
CAediting_229269chr2_189806497_+exonic
CAediting_229270chr2_189806578_+ncRNA_intronic
CAediting_229271chr2_189806587_+ncRNA_intronic
CAediting_229272chr2_189809643_+ncRNA_intronic
CAediting_229273chr2_189820524_+ncRNA_intronic
CAediting_229274chr2_189820911_+ncRNA_intronic
CAediting_229275chr2_189821195_+ncRNA_intronic
CAediting_229276chr2_189821290_+ncRNA_intronic
CAediting_229277chr2_189821293_+ncRNA_intronic
CAediting_229278chr2_189821294_+ncRNA_intronic
CAediting_229279chr2_189821296_+ncRNA_intronic
CAediting_229280chr2_189821334_+ncRNA_intronic
CAediting_229281chr2_189821407_+ncRNA_intronic
CAediting_229282chr2_189827585_+ncRNA_intronic
CAediting_229283chr2_189827586_+ncRNA_intronic
CAediting_229284chr2_189827587_+ncRNA_intronic
CAediting_229285chr2_189827647_+ncRNA_intronic
CAediting_229286chr2_189827665_+ncRNA_intronic
CAediting_229287chr2_189827666_+ncRNA_intronic
CAediting_229288chr2_189827676_+ncRNA_intronic
CAediting_229289chr2_189827677_+ncRNA_intronic
CAediting_229290chr2_189827678_+ncRNA_intronic
CAediting_229291chr2_189834913_+ncRNA_intronic
CAediting_229292chr2_189834915_+ncRNA_intronic
CAediting_229293chr2_189835664_+ncRNA_intronic
CAediting_229294chr2_189835670_+ncRNA_intronic
CAediting_229295chr2_189835692_+ncRNA_intronic
CAediting_229296chr2_189835693_+ncRNA_intronic
CAediting_229297chr2_189835725_+ncRNA_intronic
CAediting_229298chr2_189835735_+ncRNA_intronic
CAediting_229299chr2_189835736_+ncRNA_intronic
CAediting_229300chr2_189835749_+ncRNA_intronic
CAediting_229301chr2_189835776_+ncRNA_intronic
CAediting_229302chr2_189835777_+ncRNA_intronic
CAediting_229303chr2_189835778_+ncRNA_intronic
CAediting_229304chr2_189835781_+ncRNA_intronic
CAediting_229305chr2_189835794_+ncRNA_intronic
CAediting_229306chr2_189835813_+ncRNA_intronic
CAediting_229307chr2_189835834_+ncRNA_intronic
CAediting_229308chr2_189844434_+ncRNA_intronic
CAediting_229309chr2_189844497_+ncRNA_intronic
CAediting_229310chr2_189844540_+ncRNA_intronic
CAediting_229311chr2_189844545_+ncRNA_intronic
CAediting_229312chr2_189844546_+ncRNA_intronic
CAediting_229313chr2_189844564_+ncRNA_intronic
CAediting_229314chr2_189844927_+ncRNA_intronic
CAediting_229315chr2_189844935_+ncRNA_intronic
CAediting_229316chr2_189844975_+ncRNA_intronic
CAediting_229317chr2_189844991_+ncRNA_intronic
CAediting_229318chr2_189845019_+ncRNA_intronic
CAediting_229319chr2_189845110_+ncRNA_intronic
CAediting_229320chr2_189845120_+ncRNA_intronic
CAediting_229321chr2_189847045_+ncRNA_intronic
CAediting_229322chr2_189847059_+ncRNA_intronic
CAediting_229323chr2_189861579_+ncRNA_intronic
CAediting_229324chr2_189863318_+ncRNA_intronic
CAediting_229325chr2_189863354_+ncRNA_intronic
CAediting_229326chr2_189863358_+ncRNA_intronic
CAediting_229327chr2_189863437_+ncRNA_intronic
CAediting_229328chr2_189863468_+ncRNA_intronic
CAediting_229329chr2_189863506_+ncRNA_intronic
CAediting_229330chr2_189864470_+ncRNA_intronic
CAediting_229331chr2_189864472_+ncRNA_intronic
CAediting_229332chr2_189864474_+ncRNA_intronic
CAediting_229333chr2_189864479_+ncRNA_intronic
CAediting_229334chr2_189864480_+ncRNA_intronic
CAediting_229335chr2_189864491_+ncRNA_intronic
CAediting_229336chr2_189864509_+ncRNA_intronic
CAediting_229337chr2_189864525_+ncRNA_intronic
CAediting_229338chr2_189864535_+ncRNA_intronic
CAediting_229339chr2_189864606_+ncRNA_intronic
CAediting_229340chr2_189864638_+ncRNA_intronic
CAediting_229341chr2_189872702_+ncRNA_intronic
CAediting_229342chr2_189872745_+ncRNA_intronic
CAediting_229343chr2_189872750_+ncRNA_intronic
CAediting_229344chr2_189872759_+ncRNA_intronic
CAediting_229345chr2_189872762_+ncRNA_intronic
CAediting_229346chr2_189872772_+ncRNA_intronic
CAediting_229347chr2_189872774_+ncRNA_intronic
CAediting_229348chr2_189872896_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_229245chr2_189787700_+SINEMIRMIR
CAediting_229246chr2_189787717_+SINEMIRMIR
CAediting_229247chr2_189787718_+SINEMIRMIR
CAediting_229248chr2_189787721_+SINEMIRMIR
CAediting_229249chr2_189787742_+SINEMIRMIR
CAediting_229250chr2_189787749_+SINEMIRMIR
CAediting_229251chr2_189787752_+SINEMIRMIR
CAediting_229252chr2_189787755_+SINEMIRMIR
CAediting_229253chr2_189787761_+SINEMIRMIR
CAediting_229254chr2_189787774_+SINEMIRMIR
CAediting_229255chr2_189787788_+SINEMIRMIR
CAediting_229256chr2_189787790_+SINEMIRMIR
CAediting_229257chr2_189787798_+SINEMIRMIR
CAediting_229258chr2_189788429_+SINEMIRMIR
CAediting_229259chr2_189788503_+SINEMIRMIR
CAediting_229260chr2_189788515_+SINEMIRMIR
CAediting_229261chr2_189788520_+SINEMIRMIR
CAediting_229262chr2_189788521_+SINEMIRMIR
CAediting_229263chr2_189788523_+SINEMIRMIR
CAediting_229264chr2_189788527_+SINEMIRMIR
CAediting_229265chr2_189788528_+SINEMIRMIR
CAediting_229266chr2_189788531_+SINEMIRMIR
CAediting_229267chr2_189788557_+SINEMIRMIR
CAediting_229268chr2_189788558_+SINEMIRMIR
CAediting_229269chr2_189806497_+SINEAluAluJb
CAediting_229270chr2_189806578_+SINEAluAluJb
CAediting_229271chr2_189806587_+SINEAluAluJb
CAediting_229272chr2_189809643_+SINEAluAluSq2
CAediting_229273chr2_189820524_+SINEAluAluJr
CAediting_229275chr2_189821195_+SINEAluAluSc8
CAediting_229276chr2_189821290_+SINEAluAluSc8
CAediting_229277chr2_189821293_+SINEAluAluSc8
CAediting_229278chr2_189821294_+SINEAluAluSc8
CAediting_229279chr2_189821296_+SINEAluAluSc8
CAediting_229280chr2_189821334_+SINEAluAluSc8
CAediting_229281chr2_189821407_+SINEAluAluSc8
CAediting_229282chr2_189827585_+LINEL1L1MA6
CAediting_229283chr2_189827586_+LINEL1L1MA6
CAediting_229284chr2_189827587_+LINEL1L1MA6
CAediting_229285chr2_189827647_+LINEL1L1MA6
CAediting_229286chr2_189827665_+LINEL1L1MA6
CAediting_229287chr2_189827666_+LINEL1L1MA6
CAediting_229288chr2_189827676_+LINEL1L1MA6
CAediting_229289chr2_189827677_+LINEL1L1MA6
CAediting_229290chr2_189827678_+LINEL1L1MA6
CAediting_229291chr2_189834913_+SINEAluAluJo
CAediting_229292chr2_189834915_+SINEAluAluJo
CAediting_229293chr2_189835664_+SINEAluAluJb
CAediting_229294chr2_189835670_+SINEAluAluJb
CAediting_229295chr2_189835692_+SINEAluAluJb
CAediting_229296chr2_189835693_+SINEAluAluJb
CAediting_229297chr2_189835725_+SINEAluAluJb
CAediting_229298chr2_189835735_+SINEAluAluJb
CAediting_229299chr2_189835736_+SINEAluAluJb
CAediting_229300chr2_189835749_+SINEAluAluJb
CAediting_229301chr2_189835776_+SINEAluAluJb
CAediting_229302chr2_189835777_+SINEAluAluJb
CAediting_229303chr2_189835778_+SINEAluAluJb
CAediting_229304chr2_189835781_+SINEAluAluJb
CAediting_229305chr2_189835794_+SINEAluAluJb
CAediting_229306chr2_189835813_+SINEAluAluJb
CAediting_229307chr2_189835834_+SINEAluAluJb
CAediting_229308chr2_189844434_+SINEAluAluSx
CAediting_229309chr2_189844497_+SINEAluAluSx
CAediting_229310chr2_189844540_+SINEAluAluSx
CAediting_229311chr2_189844545_+SINEAluAluSx
CAediting_229312chr2_189844546_+SINEAluAluSx
CAediting_229313chr2_189844564_+SINEAluAluSx
CAediting_229314chr2_189844927_+SINEAluAluSx
CAediting_229315chr2_189844935_+SINEAluAluSx
CAediting_229316chr2_189844975_+SINEAluAluSx
CAediting_229317chr2_189844991_+SINEAluAluSx
CAediting_229318chr2_189845019_+SINEAluAluSx
CAediting_229319chr2_189845110_+SINEAluAluSx
CAediting_229320chr2_189845120_+SINEAluAluSx
CAediting_229321chr2_189847045_+SINEAluAluSg
CAediting_229322chr2_189847059_+SINEAluAluSg
CAediting_229323chr2_189861579_+SINEAluAluSx
CAediting_229324chr2_189863318_+SINEAluAluSx
CAediting_229325chr2_189863354_+SINEAluAluSx
CAediting_229326chr2_189863358_+SINEAluAluSx
CAediting_229327chr2_189863437_+SINEAluAluSx
CAediting_229328chr2_189863468_+SINEAluAluSx
CAediting_229329chr2_189863506_+SINEAluAluSx
CAediting_229330chr2_189864470_+SINEAluAluSg
CAediting_229331chr2_189864472_+SINEAluAluSg
CAediting_229332chr2_189864474_+SINEAluAluSg
CAediting_229333chr2_189864479_+SINEAluAluSg
CAediting_229334chr2_189864480_+SINEAluAluSg
CAediting_229335chr2_189864491_+SINEAluAluSg
CAediting_229336chr2_189864509_+SINEAluAluSg
CAediting_229337chr2_189864525_+SINEAluAluSg
CAediting_229338chr2_189864535_+SINEAluAluSg
CAediting_229339chr2_189864606_+SINEAluAluSg
CAediting_229340chr2_189864638_+SINEAluAluSg
CAediting_229341chr2_189872702_+SINEAluAluSx3
CAediting_229342chr2_189872745_+SINEAluAluSx3
CAediting_229343chr2_189872750_+SINEAluAluSx3
CAediting_229344chr2_189872759_+SINEAluAluSx3
CAediting_229345chr2_189872762_+SINEAluAluSx3
CAediting_229346chr2_189872772_+SINEAluAluSx3
CAediting_229347chr2_189872774_+SINEAluAluSx3
CAediting_229348chr2_189872896_+SINEAluAluSx3

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RNA A-to-I editing events in the alternative splicing sites for PMS1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000064933.15.PMS1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000064933.15.PMS1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PMS1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for PMS1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for PMS1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000409985hsa-miR-340-3p1898065811898065877mer-m8189806567189806588149.00-17.74
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000409985hsa-miR-6827-3p1898065811898065877mer-m8189806568189806588153.00-17.53
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000374826hsa-miR-340-3p1898065811898065877mer-m8189806567189806588149.00-17.74
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000374826hsa-miR-6827-3p1898065811898065877mer-m8189806568189806588153.00-17.53

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000409985hsa-miR-10a-5p1898065841898065907mer-m8189806569189806591145-13.67
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000409985hsa-miR-10b-5p1898065841898065907mer-m8189806569189806591140-13.05
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000409985hsa-miR-339-5p1898065831898065897mer-m8189806566189806590151-18.58
CAediting_229269chr2_189806497_+ENSG00000064933.15ENST00000409985hsa-miR-3614-5p1898064951898065017mer-1a189806478189806501147-23.09
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000409985hsa-miR-44211898065821898065887mer-m8189806568189806589154-16.19
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000409985hsa-miR-5699-3p1898065821898065887mer-m8189806568189806589153-17.34
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000409985hsa-miR-6818-3p1898065801898065867mer-m8189806566189806587140-12.56
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000374826hsa-miR-10a-5p1898065841898065907mer-m8189806569189806591145-13.67
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000374826hsa-miR-10b-5p1898065841898065907mer-m8189806569189806591140-13.05
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000374826hsa-miR-339-5p1898065831898065897mer-m8189806566189806590151-18.58
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000374826hsa-miR-44211898065821898065887mer-m8189806568189806589154-16.19
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000374826hsa-miR-5699-3p1898065821898065887mer-m8189806568189806589153-17.34
CAediting_229271chr2_189806587_+ENSG00000064933.15ENST00000374826hsa-miR-6818-3p1898065801898065867mer-m8189806566189806587140-12.56

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_442554chr5_154685830_+ENSG00000064933.15ENST00000409985hsa-miR-13031898069201898069267mer-m8189806906189806927145-12.71
CAediting_1160181chr17_7017644_-ENSG00000064933.15ENST00000342075hsa-miR-195-3p1898545501898545578mer-1a189854536189854557152-12.36
CAediting_117844chr1_162342605_+ENSG00000064933.15ENST00000342075hsa-miR-556-3p1898546791898546868mer-1a189854665189854686162-14.23
CAediting_228905chr2_188297554_+ENSG00000064933.15ENST00000342075hsa-miR-561-3p1898547351898547417mer-m8189854717189854742155-14.06
CAediting_1229413chr17_67471544_+ENSG00000064933.15ENST00000342075hsa-miR-548aa1898679031898679108mer-1a189867888189867910144-10.65
CAediting_1229413chr17_67471544_+ENSG00000064933.15ENST00000450931hsa-miR-548aa1898679031898679108mer-1a189867888189867910144-10.65
CAediting_468389chr6_31355314_-ENSG00000064933.15ENST00000409985hsa-miR-6891-5p1898065161898065238mer-1a189806505189806523153-26.99
CAediting_468389chr6_31355314_-ENSG00000064933.15ENST00000374826hsa-miR-6891-5p1898065161898065238mer-1a189806505189806523153-26.99

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_442554chr5_154685830_+ENSG00000064933.15ENST00000409985hsa-miR-13031898067121898067198mer-1a189806698189806719140-9.91
CAediting_1229415chr17_67471547_+ENSG00000064933.15ENST00000409985hsa-miR-548aa1898070021898070087mer-m8189806986189807009152-12.99
CAediting_1160181chr17_7017644_-ENSG00000064933.15ENST00000342075hsa-miR-195-3p1898548021898548098mer-1a189854790189854809153-10.92

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PMS1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000374826.7protein_codingSoverviewSoverview
ENST00000409985.4protein_codingSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_229269ENST00000374826.7chr2_189806497_+-284.50-282.80-288.70
CAediting_229270ENST00000374826.7chr2_189806578_+-286.30-282.80-288.70
CAediting_229271ENST00000374826.7chr2_189806587_+-283.50-282.80-288.70
CAediting_229269ENST00000409985.4chr2_189806497_+-494.60-492.90-501.30
CAediting_229270ENST00000409985.4chr2_189806578_+-494.80-492.90-501.30
CAediting_229271ENST00000409985.4chr2_189806587_+-497.90-492.90-501.30

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Relation with ADAR for PMS1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for PMS1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for PMS1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for PMS1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PMS1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
PMS1C0033578Prostatic Neoplasms1CTD_human
PMS1C0376358Malignant neoplasm of prostate1CTD_human