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Editing gene: HSPB11 (CAeditome ID:51668)

Gene summary for HSPB11

Gene summary

Gene information	Gene symbol	HSPB11
	Gene ID	51668
	Gene name	heat shock protein family B (small) member 11
	Synonyms	C1orf41\|FAP232\|HSPCO34\|IFT25\|PP25
	Cytomap	1p32.3
	Type of gene	protein-coding
	Description	intraflagellar transport protein 25 homologheat shock protein beta-11heat shock protein family B (small), member 11intraflagellar transport 25 homologplacental protein 25
	Modification date	20210518
	UniProtAcc	Q9Y547
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for HSPB11

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000081870.10

RNA A-to-I editing events in Cancer.

CAediting_66344(53916907, -), CAediting_66345(53916925, -), CAediting_66346(53916937, -), CAediting_66347(53916959, -), CAediting_66348(53916974, -), CAediting_66349(53916979, -), CAediting_66350(53917000, -), CAediting_66351(53917022, -), CAediting_66352(53917032, -), CAediting_66353(53917044, -), CAediting_66354(53917061, -), CAediting_66355(53917062, -), CAediting_66356(53917081, -), CAediting_66357(53917097, -), CAediting_66358(53917105, -), CAediting_66359(53917111, -), CAediting_66360(53917623, -), CAediting_66361(53917629, -), CAediting_66362(53919879, -), CAediting_66363(53919932, -), CAediting_66364(53919948, -), CAediting_66365(53920032, -), CAediting_66366(53920050, -), CAediting_66367(53920749, -), CAediting_66368(53920750, -), CAediting_66369(53920805, -), CAediting_66370(53920806, -), CAediting_66371(53920811, -), CAediting_66372(53920981, -), CAediting_66373(53920993, -), CAediting_66374(53921990, -), CAediting_66375(53922001, -), CAediting_66376(53922003, -), CAediting_66377(53922011, -), CAediting_66378(53922021, -), CAediting_66379(53922026, -), CAediting_66380(53922032, -), CAediting_66381(53922060, -), CAediting_66382(53922065, -), CAediting_66383(53922066, -), CAediting_66384(53922074, -), CAediting_66385(53922079, -), CAediting_66386(53922091, -), CAediting_66387(53922125, -), CAediting_66388(53922129, -), CAediting_66389(53922136, -), CAediting_66390(53922138, -), CAediting_66391(53922150, -), CAediting_66392(53922151, -), CAediting_66393(53922152, -), CAediting_66394(53922191, -), CAediting_66395(53922192, -), CAediting_66396(53922203, -), CAediting_66397(53922223, -), CAediting_66398(53922225, -), CAediting_66399(53922227, -), CAediting_66400(53922229, -), CAediting_66401(53922232, -), CAediting_66402(53922250, -), CAediting_66403(53922272, -), CAediting_66404(53922294, -), CAediting_66405(53922347, -), CAediting_66406(53922361, -), CAediting_66407(53922393, -), CAediting_66408(53924580, -), CAediting_66409(53924647, -), CAediting_66410(53924715, -), CAediting_66411(53925842, -), CAediting_66412(53925984, -), CAediting_66413(53926284, -), CAediting_66414(53926366, -), CAediting_66415(53926752, -), CAediting_66416(53926788, -), CAediting_66417(53926860, -), CAediting_66418(53926861, -), CAediting_66419(53926883, -), CAediting_66420(53926887, -), CAediting_66421(53926890, -), CAediting_66422(53926891, -), CAediting_66423(53926920, -), CAediting_66424(53926921, -), CAediting_66425(53926928, -), CAediting_66426(53926933, -), CAediting_66427(53926943, -), CAediting_66428(53926944, -), CAediting_66429(53926971, -), CAediting_66430(53926997, -), CAediting_66431(53927014, -), CAediting_66432(53932095, -), CAediting_66433(53932188, -), CAediting_66434(53932229, -), CAediting_66435(53932234, -), CAediting_66436(53932239, -), CAediting_66437(53932243, -), CAediting_66438(53932271, -), CAediting_66439(53932282, -), CAediting_66440(53932287, -), CAediting_66441(53932633, -), CAediting_66442(53932703, -), CAediting_66443(53932754, -), CAediting_66444(53932839, -), CAediting_66445(53933183, -), CAediting_66446(53933202, -), CAediting_66447(53933203, -), CAediting_66448(53933267, -), CAediting_66449(53933273, -), CAediting_66450(53935719, -), CAediting_66451(53935723, -), CAediting_66452(53935724, -), CAediting_66453(53935728, -), CAediting_66454(53935748, -), CAediting_66455(53936443, -),

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RNA editing positional annotations for HSPB11 using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_66353	chr1_53917044_-	nonsynonymous SNV	ENST00000371378.5	c.A391G	p.S131G	D	.	N

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_66344	chr1_53916907_-	exonic
CAediting_66345	chr1_53916925_-	exonic
CAediting_66346	chr1_53916937_-	exonic
CAediting_66347	chr1_53916959_-	exonic
CAediting_66348	chr1_53916974_-	exonic
CAediting_66349	chr1_53916979_-	exonic
CAediting_66350	chr1_53917000_-	exonic
CAediting_66351	chr1_53917022_-	exonic
CAediting_66352	chr1_53917032_-	exonic
CAediting_66353	chr1_53917044_-	exonic
CAediting_66354	chr1_53917061_-	exonic
CAediting_66355	chr1_53917062_-	exonic
CAediting_66356	chr1_53917081_-	exonic
CAediting_66357	chr1_53917097_-	exonic
CAediting_66358	chr1_53917105_-	exonic
CAediting_66359	chr1_53917111_-	exonic
CAediting_66360	chr1_53917623_-	intronic
CAediting_66361	chr1_53917629_-	intronic
CAediting_66362	chr1_53919879_-	intronic
CAediting_66363	chr1_53919932_-	intronic
CAediting_66364	chr1_53919948_-	intronic
CAediting_66365	chr1_53920032_-	intronic
CAediting_66366	chr1_53920050_-	intronic
CAediting_66367	chr1_53920749_-	intronic
CAediting_66368	chr1_53920750_-	intronic
CAediting_66369	chr1_53920805_-	intronic
CAediting_66370	chr1_53920806_-	intronic
CAediting_66371	chr1_53920811_-	intronic
CAediting_66372	chr1_53920981_-	intronic
CAediting_66373	chr1_53920993_-	intronic
CAediting_66374	chr1_53921990_-	ncRNA_intronic
CAediting_66375	chr1_53922001_-	ncRNA_intronic
CAediting_66376	chr1_53922003_-	ncRNA_intronic
CAediting_66377	chr1_53922011_-	ncRNA_intronic
CAediting_66378	chr1_53922021_-	ncRNA_intronic
CAediting_66379	chr1_53922026_-	ncRNA_intronic
CAediting_66380	chr1_53922032_-	ncRNA_intronic
CAediting_66381	chr1_53922060_-	ncRNA_intronic
CAediting_66382	chr1_53922065_-	ncRNA_intronic
CAediting_66383	chr1_53922066_-	ncRNA_intronic
CAediting_66384	chr1_53922074_-	ncRNA_intronic
CAediting_66385	chr1_53922079_-	ncRNA_intronic
CAediting_66386	chr1_53922091_-	ncRNA_intronic
CAediting_66387	chr1_53922125_-	ncRNA_intronic
CAediting_66388	chr1_53922129_-	ncRNA_intronic
CAediting_66389	chr1_53922136_-	ncRNA_intronic
CAediting_66390	chr1_53922138_-	ncRNA_intronic
CAediting_66391	chr1_53922150_-	ncRNA_intronic
CAediting_66392	chr1_53922151_-	ncRNA_intronic
CAediting_66393	chr1_53922152_-	ncRNA_intronic
CAediting_66394	chr1_53922191_-	ncRNA_intronic
CAediting_66395	chr1_53922192_-	ncRNA_intronic
CAediting_66396	chr1_53922203_-	ncRNA_intronic
CAediting_66397	chr1_53922223_-	ncRNA_intronic
CAediting_66398	chr1_53922225_-	ncRNA_intronic
CAediting_66399	chr1_53922227_-	ncRNA_intronic
CAediting_66400	chr1_53922229_-	ncRNA_intronic
CAediting_66401	chr1_53922232_-	ncRNA_intronic
CAediting_66402	chr1_53922250_-	ncRNA_intronic
CAediting_66403	chr1_53922272_-	ncRNA_intronic
CAediting_66404	chr1_53922294_-	ncRNA_intronic
CAediting_66405	chr1_53922347_-	ncRNA_intronic
CAediting_66406	chr1_53922361_-	ncRNA_intronic
CAediting_66407	chr1_53922393_-	ncRNA_intronic
CAediting_66408	chr1_53924580_-	ncRNA_intronic
CAediting_66409	chr1_53924647_-	ncRNA_intronic
CAediting_66410	chr1_53924715_-	ncRNA_intronic
CAediting_66411	chr1_53925842_-	ncRNA_intronic
CAediting_66412	chr1_53925984_-	ncRNA_intronic
CAediting_66413	chr1_53926284_-	ncRNA_intronic
CAediting_66414	chr1_53926366_-	ncRNA_intronic
CAediting_66415	chr1_53926752_-	ncRNA_intronic
CAediting_66416	chr1_53926788_-	ncRNA_intronic
CAediting_66417	chr1_53926860_-	ncRNA_intronic
CAediting_66418	chr1_53926861_-	ncRNA_intronic
CAediting_66419	chr1_53926883_-	ncRNA_intronic
CAediting_66420	chr1_53926887_-	ncRNA_intronic
CAediting_66421	chr1_53926890_-	ncRNA_intronic
CAediting_66422	chr1_53926891_-	ncRNA_intronic
CAediting_66423	chr1_53926920_-	ncRNA_intronic
CAediting_66424	chr1_53926921_-	ncRNA_intronic
CAediting_66425	chr1_53926928_-	ncRNA_intronic
CAediting_66426	chr1_53926933_-	ncRNA_intronic
CAediting_66427	chr1_53926943_-	ncRNA_intronic
CAediting_66428	chr1_53926944_-	ncRNA_intronic
CAediting_66429	chr1_53926971_-	ncRNA_intronic
CAediting_66430	chr1_53926997_-	ncRNA_intronic
CAediting_66431	chr1_53927014_-	ncRNA_intronic
CAediting_66432	chr1_53932095_-	intronic
CAediting_66433	chr1_53932188_-	intronic
CAediting_66434	chr1_53932229_-	intronic
CAediting_66435	chr1_53932234_-	intronic
CAediting_66436	chr1_53932239_-	intronic
CAediting_66437	chr1_53932243_-	intronic
CAediting_66438	chr1_53932271_-	intronic
CAediting_66439	chr1_53932282_-	intronic
CAediting_66440	chr1_53932287_-	intronic
CAediting_66441	chr1_53932633_-	intronic
CAediting_66442	chr1_53932703_-	intronic
CAediting_66443	chr1_53932754_-	intronic
CAediting_66444	chr1_53932839_-	intronic
CAediting_66445	chr1_53933183_-	intronic
CAediting_66446	chr1_53933202_-	intronic
CAediting_66447	chr1_53933203_-	intronic
CAediting_66448	chr1_53933267_-	intronic
CAediting_66449	chr1_53933273_-	intronic
CAediting_66450	chr1_53935719_-	intronic
CAediting_66451	chr1_53935723_-	intronic
CAediting_66452	chr1_53935724_-	intronic
CAediting_66453	chr1_53935728_-	intronic
CAediting_66454	chr1_53935748_-	intronic
CAediting_66455	chr1_53936443_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_66344	chr1_53916907_-	SINE	Alu	AluSq2
CAediting_66345	chr1_53916925_-	SINE	Alu	AluSq2
CAediting_66346	chr1_53916937_-	SINE	Alu	AluSq2
CAediting_66347	chr1_53916959_-	SINE	Alu	AluSq2
CAediting_66348	chr1_53916974_-	SINE	Alu	AluSq2
CAediting_66349	chr1_53916979_-	SINE	Alu	AluSq2
CAediting_66350	chr1_53917000_-	SINE	Alu	AluSq2
CAediting_66351	chr1_53917022_-	SINE	Alu	AluSq2
CAediting_66352	chr1_53917032_-	SINE	Alu	AluSq2
CAediting_66353	chr1_53917044_-	SINE	Alu	AluSq2
CAediting_66354	chr1_53917061_-	SINE	Alu	AluSq2
CAediting_66355	chr1_53917062_-	SINE	Alu	AluSq2
CAediting_66356	chr1_53917081_-	SINE	Alu	AluSq2
CAediting_66357	chr1_53917097_-	SINE	Alu	AluSq2
CAediting_66358	chr1_53917105_-	SINE	Alu	AluSq2
CAediting_66359	chr1_53917111_-	SINE	Alu	AluSq2
CAediting_66360	chr1_53917623_-	SINE	Alu	AluSq
CAediting_66361	chr1_53917629_-	SINE	Alu	AluSq
CAediting_66362	chr1_53919879_-	SINE	Alu	AluJr
CAediting_66363	chr1_53919932_-	SINE	Alu	AluJr
CAediting_66364	chr1_53919948_-	SINE	Alu	AluJr
CAediting_66365	chr1_53920032_-	SINE	Alu	AluJr
CAediting_66366	chr1_53920050_-	SINE	Alu	AluJr
CAediting_66367	chr1_53920749_-	SINE	Alu	AluJr
CAediting_66368	chr1_53920750_-	SINE	Alu	AluJr
CAediting_66369	chr1_53920805_-	SINE	Alu	AluJr
CAediting_66370	chr1_53920806_-	SINE	Alu	AluJr
CAediting_66371	chr1_53920811_-	SINE	Alu	AluJr
CAediting_66372	chr1_53920981_-	SINE	Alu	AluJb
CAediting_66373	chr1_53920993_-	SINE	Alu	AluJb
CAediting_66374	chr1_53921990_-	SINE	Alu	AluJr
CAediting_66375	chr1_53922001_-	SINE	Alu	AluJr
CAediting_66376	chr1_53922003_-	SINE	Alu	AluJr
CAediting_66377	chr1_53922011_-	SINE	Alu	AluJr
CAediting_66378	chr1_53922021_-	SINE	Alu	AluJr
CAediting_66379	chr1_53922026_-	SINE	Alu	AluJr
CAediting_66380	chr1_53922032_-	SINE	Alu	AluJr
CAediting_66381	chr1_53922060_-	SINE	Alu	AluJr
CAediting_66382	chr1_53922065_-	SINE	Alu	AluJr
CAediting_66383	chr1_53922066_-	SINE	Alu	AluJr
CAediting_66384	chr1_53922074_-	SINE	Alu	AluJr
CAediting_66385	chr1_53922079_-	SINE	Alu	AluJr
CAediting_66387	chr1_53922125_-	SINE	Alu	AluSp
CAediting_66388	chr1_53922129_-	SINE	Alu	AluSp
CAediting_66389	chr1_53922136_-	SINE	Alu	AluSp
CAediting_66390	chr1_53922138_-	SINE	Alu	AluSp
CAediting_66391	chr1_53922150_-	SINE	Alu	AluSp
CAediting_66392	chr1_53922151_-	SINE	Alu	AluSp
CAediting_66393	chr1_53922152_-	SINE	Alu	AluSp
CAediting_66394	chr1_53922191_-	SINE	Alu	AluSp
CAediting_66395	chr1_53922192_-	SINE	Alu	AluSp
CAediting_66396	chr1_53922203_-	SINE	Alu	AluSp
CAediting_66397	chr1_53922223_-	SINE	Alu	AluSp
CAediting_66398	chr1_53922225_-	SINE	Alu	AluSp
CAediting_66399	chr1_53922227_-	SINE	Alu	AluSp
CAediting_66400	chr1_53922229_-	SINE	Alu	AluSp
CAediting_66401	chr1_53922232_-	SINE	Alu	AluSp
CAediting_66402	chr1_53922250_-	SINE	Alu	AluSp
CAediting_66403	chr1_53922272_-	SINE	Alu	AluSp
CAediting_66404	chr1_53922294_-	SINE	Alu	AluSp
CAediting_66405	chr1_53922347_-	SINE	Alu	AluSp
CAediting_66406	chr1_53922361_-	SINE	Alu	AluSp
CAediting_66407	chr1_53922393_-	SINE	Alu	AluSp
CAediting_66408	chr1_53924580_-	SINE	Alu	AluY
CAediting_66409	chr1_53924647_-	SINE	Alu	AluY
CAediting_66410	chr1_53924715_-	SINE	Alu	AluY
CAediting_66411	chr1_53925842_-	SINE	Alu	AluSz
CAediting_66412	chr1_53925984_-	SINE	Alu	AluSz
CAediting_66413	chr1_53926284_-	SINE	Alu	AluJb
CAediting_66414	chr1_53926366_-	SINE	Alu	AluJb
CAediting_66415	chr1_53926752_-	SINE	Alu	AluJr
CAediting_66416	chr1_53926788_-	SINE	Alu	AluJr
CAediting_66417	chr1_53926860_-	SINE	Alu	AluJr
CAediting_66418	chr1_53926861_-	SINE	Alu	AluJr
CAediting_66419	chr1_53926883_-	SINE	Alu	AluJr
CAediting_66420	chr1_53926887_-	SINE	Alu	AluJr
CAediting_66421	chr1_53926890_-	SINE	Alu	AluJr
CAediting_66422	chr1_53926891_-	SINE	Alu	AluJr
CAediting_66423	chr1_53926920_-	SINE	Alu	AluJr
CAediting_66424	chr1_53926921_-	SINE	Alu	AluJr
CAediting_66425	chr1_53926928_-	SINE	Alu	AluJr
CAediting_66426	chr1_53926933_-	SINE	Alu	AluJr
CAediting_66427	chr1_53926943_-	SINE	Alu	AluJr
CAediting_66428	chr1_53926944_-	SINE	Alu	AluJr
CAediting_66429	chr1_53926971_-	SINE	Alu	AluJr
CAediting_66430	chr1_53926997_-	SINE	Alu	AluJr
CAediting_66431	chr1_53927014_-	SINE	Alu	AluJr
CAediting_66432	chr1_53932095_-	SINE	Alu	AluSx
CAediting_66433	chr1_53932188_-	SINE	Alu	AluSx
CAediting_66434	chr1_53932229_-	SINE	Alu	AluSx
CAediting_66435	chr1_53932234_-	SINE	Alu	AluSx
CAediting_66436	chr1_53932239_-	SINE	Alu	AluSx
CAediting_66437	chr1_53932243_-	SINE	Alu	AluSx
CAediting_66438	chr1_53932271_-	SINE	Alu	AluSx
CAediting_66439	chr1_53932282_-	SINE	Alu	AluSx
CAediting_66440	chr1_53932287_-	SINE	Alu	AluSx
CAediting_66441	chr1_53932633_-	SINE	Alu	AluJb
CAediting_66442	chr1_53932703_-	SINE	Alu	AluJb
CAediting_66443	chr1_53932754_-	SINE	Alu	AluJb
CAediting_66444	chr1_53932839_-	SINE	Alu	AluJb
CAediting_66445	chr1_53933183_-	SINE	Alu	AluY
CAediting_66446	chr1_53933202_-	SINE	Alu	AluY
CAediting_66447	chr1_53933203_-	SINE	Alu	AluY
CAediting_66448	chr1_53933267_-	SINE	Alu	AluY
CAediting_66449	chr1_53933273_-	SINE	Alu	AluY
CAediting_66450	chr1_53935719_-	SINE	Alu	FLAM_C
CAediting_66451	chr1_53935723_-	SINE	Alu	FLAM_C
CAediting_66452	chr1_53935724_-	SINE	Alu	FLAM_C
CAediting_66453	chr1_53935728_-	SINE	Alu	FLAM_C
CAediting_66454	chr1_53935748_-	SINE	Alu	FLAM_C
CAediting_66455	chr1_53936443_-	SINE	Alu	AluSx3

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RNA A-to-I editing events in the alternative splicing sites for HSPB11

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_66407	chr1_53922393_-	53922389:53922411	3SS	0+2i	TTTTTTTTTTTTTTTTTGAGACG	3.97	TTTTTTTTTTTTTTTTTGGGACG	-3.99

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000081870.10.HSPB11.

Correlation between RNA A-to-I editing and PSI for ENSG00000081870.10.HSPB11.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HSPB11

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

CESC.CAediting_66401.ENSG00000081870.HSPB11.png
Soverview

OV.CAediting_66382.ENSG00000081870.HSPB11.png
Soverview

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Protein coding region RNA A-to-I editings for HSPB11

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for HSPB11

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_228905	chr2_188297554_+	ENSG00000081870.10	ENST00000371376	hsa-miR-561-3p	53929920	53929926	7mer-m8	53929919	53929944	151	-9.41

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for HSPB11

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000371378.5	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_66344	ENST00000371378.5	chr1_53916907_-	-238.10	-238.10	-258.70
CAediting_66345	ENST00000371378.5	chr1_53916925_-	-238.10	-238.10	-258.70
CAediting_66346	ENST00000371378.5	chr1_53916937_-	-238.10	-238.10	-258.70
CAediting_66347	ENST00000371378.5	chr1_53916959_-	-237.00	-238.10	-258.70
CAediting_66348	ENST00000371378.5	chr1_53916974_-	-237.70	-238.10	-258.70
CAediting_66349	ENST00000371378.5	chr1_53916979_-	-238.00	-238.10	-258.70
CAediting_66350	ENST00000371378.5	chr1_53917000_-	-237.40	-238.10	-258.70
CAediting_66351	ENST00000371378.5	chr1_53917022_-	-239.90	-238.10	-258.70
CAediting_66352	ENST00000371378.5	chr1_53917032_-	-239.10	-238.10	-258.70
CAediting_66353	ENST00000371378.5	chr1_53917044_-	-240.70	-238.10	-258.70
CAediting_66354	ENST00000371378.5	chr1_53917061_-	-241.30	-238.10	-258.70
CAediting_66355	ENST00000371378.5	chr1_53917062_-	-240.10	-238.10	-258.70
CAediting_66356	ENST00000371378.5	chr1_53917081_-	-238.40	-238.10	-258.70
CAediting_66357	ENST00000371378.5	chr1_53917097_-	-238.10	-238.10	-258.70
CAediting_66358	ENST00000371378.5	chr1_53917105_-	-240.70	-238.10	-258.70
CAediting_66359	ENST00000371378.5	chr1_53917111_-	-240.40	-238.10	-258.70

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Relation with ADAR for HSPB11

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
THCA	CAediting_66382	chr1_53922065_-	0.00105807592121984	0.422582535401765	.	.	.	.
BRCA	CAediting_66390	chr1_53922138_-	.	.	0.00367955287928421	0.308223659383096	.	.
KIRC	CAediting_66390	chr1_53922138_-	.	.	0.0033721773812099	0.287655654255799	.	.
BLCA	CAediting_66391	chr1_53922150_-	0.00239910070333794	0.293231170359135	.	.	.	.
BRCA	CAediting_66391	chr1_53922150_-	0.0384411731066173	0.13262088117928	.	.	.	.
THCA	CAediting_66391	chr1_53922150_-	0.00821756087793818	0.163281805199883	.	.	.	.
KIRP	CAediting_66391	chr1_53922150_-	0.043682018468175	0.255022313657155	0.0202092349405961	0.292037989744799	.	.
UCEC	CAediting_66397	chr1_53922223_-	0.0196537548605958	0.300499277165732	.	.	.	.
OV	CAediting_66397	chr1_53922223_-	0.0306787980898932	0.158108323582668	.	.	.	.
THYM	CAediting_66397	chr1_53922223_-	0.00313891399106583	0.384591437616421	0.00641175722843457	0.35698834229298	.	.
THCA	CAediting_66398	chr1_53922225_-	0.00711019629323354	0.372471040564773	.	.	.	.
THCA	CAediting_66400	chr1_53922229_-	0.0355610196340227	0.148732184272061	.	.	.	.
KIRP	CAediting_66400	chr1_53922229_-	0.000822344726967696	0.45386713335628	.	.	.	.
BLCA	CAediting_66401	chr1_53922232_-	0.0118265028696157	0.253370723771573	.	.	.	.
BRCA	CAediting_66401	chr1_53922232_-	0.00509881228450753	0.193985856998154	.	.	.	.
THYM	CAediting_66401	chr1_53922232_-	0.00564878646891276	0.36519227163669	.	.	0.0231275083422441	0.303173882947443

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Relation with cancer stages for HSPB11

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_66391	chr1_53922150_-	0.00212881356290771	0.297929481716791
BLCA	pathologic_stage	CAediting_66397	chr1_53922223_-	0.000292634350572973	0.363593002959456
BLCA	pathologic_stage	CAediting_66401	chr1_53922232_-	0.001043810939673	0.326248258693537
BRCA	pathologic_stage	CAediting_66401	chr1_53922232_-	0.00928572224715508	0.182173655598444
KIRP	clinical_stage	CAediting_66400	chr1_53922229_-	0.00646424262498292	0.486061496970017
OV	clinical_stage	CAediting_66397	chr1_53922223_-	0.0434399292398474	-0.14865488555943
OV	clinical_stage	CAediting_66400	chr1_53922229_-	0.0407539820977663	0.171333561708864
THCA	pathologic_stage	CAediting_66397	chr1_53922223_-	0.0194128660737127	0.153384065030521
THCA	pathologic_stage	CAediting_66399	chr1_53922227_-	0.0133453832002883	0.325960515036691

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Relation with survival for HSPB11

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
KIRC	CAediting_66382	chr1_53922065_-	0.0114601482959867	0.0389988	62.0523

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RelatedDrugs for HSPB11

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for HSPB11

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene