CAeditome Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: AZIN1 (CAeditome ID:51582)

Gene summary for AZIN1

check button Gene summary
Gene informationGene symbol

AZIN1

Gene ID

51582

Gene nameantizyme inhibitor 1
SynonymsAZI|AZI1|AZIA1|OAZI|OAZIN|ODC1L
Cytomap

8q22.3

Type of geneprotein-coding
Descriptionantizyme inhibitor 1ornithine decarboxylase antizyme inhibitor
Modification date20210518
UniProtAcc

O14977

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
AZIN1

GO:0042978

Antizyme inhibitor 1

17900240

AZIN1

GO:0042177

Antizyme inhibitor 1

17900240

AZIN1

GO:1902269

Antizyme inhibitor 1

18508777


Top

RNA A-to-I events for AZIN1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000155096.12
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_655260(102829408, -), CAediting_655261(102830135, -), CAediting_655262(102830141, -), CAediting_655263(102830156, -), CAediting_655264(102830258, -), CAediting_655265(102830264, -), CAediting_655266(102830278, -), CAediting_655267(102830294, -), CAediting_655268(102830639, -), CAediting_655269(102831535, -), CAediting_655270(102831586, -), CAediting_655271(102832749, -), CAediting_655272(102832778, -), CAediting_655273(102832785, -), CAediting_655274(102832805, -), CAediting_655275(102832834, -), CAediting_655276(102832869, -), CAediting_655277(102832874, -), CAediting_655278(102833053, -), CAediting_655279(102833659, -), CAediting_655280(102833686, -), CAediting_655281(102833718, -), CAediting_655282(102833739, -), CAediting_655283(102833814, -), CAediting_655284(102833815, -), CAediting_655285(102840403, -), CAediting_655286(102840416, -), CAediting_655287(102840447, -), CAediting_655288(102840489, -), CAediting_655289(102840491, -), CAediting_655290(102842051, -), CAediting_655291(102842104, -), CAediting_655292(102842105, -), CAediting_655293(102842863, -), CAediting_655294(102844296, -), CAediting_655295(102847736, -), CAediting_655296(102847764, -), CAediting_655297(102847793, -), CAediting_655298(102848519, -), CAediting_655299(102848529, -), CAediting_655300(102849210, -), CAediting_655301(102851464, -), CAediting_655302(102851473, -), CAediting_655303(102851514, -), CAediting_655304(102851637, -), CAediting_655305(102851643, -), CAediting_655306(102851644, -), CAediting_655307(102853242, -), CAediting_655308(102853248, -), CAediting_655309(102853254, -), CAediting_655310(102853260, -), CAediting_655311(102853318, -), CAediting_655312(102853323, -), CAediting_655313(102853337, -), CAediting_655314(102853380, -), CAediting_655315(102853450, -), CAediting_655316(102853471, -), CAediting_655317(102853501, -), CAediting_655318(102853984, -), CAediting_655319(102854009, -), CAediting_655320(102854014, -), CAediting_655321(102854018, -), CAediting_655322(102854067, -), CAediting_655323(102854072, -), CAediting_655324(102854073, -), CAediting_655325(102854099, -), CAediting_655326(102854181, -), CAediting_655327(102854214, -), CAediting_655328(102854218, -), CAediting_655329(102854408, -), CAediting_655330(102854419, -), CAediting_655331(102861313, -), CAediting_655332(102861325, -), CAediting_655333(102861783, -), CAediting_655334(102861868, -), CAediting_655335(102861869, -), CAediting_655336(102861870, -), CAediting_655337(102861873, -), CAediting_655338(102861914, -), CAediting_655339(102861936, -), CAediting_655340(102861954, -),

Top

RNA editing positional annotations for AZIN1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_655260chr8_102829408_-exonic
CAediting_655261chr8_102830135_-ncRNA_exonic
CAediting_655262chr8_102830141_-ncRNA_exonic
CAediting_655263chr8_102830156_-ncRNA_exonic
CAediting_655264chr8_102830258_-intronic
CAediting_655265chr8_102830264_-intronic
CAediting_655266chr8_102830278_-intronic
CAediting_655267chr8_102830294_-intronic
CAediting_655268chr8_102830639_-intronic
CAediting_655269chr8_102831535_-intronic
CAediting_655270chr8_102831586_-intronic
CAediting_655271chr8_102832749_-intronic
CAediting_655272chr8_102832778_-intronic
CAediting_655273chr8_102832785_-intronic
CAediting_655274chr8_102832805_-intronic
CAediting_655275chr8_102832834_-intronic
CAediting_655276chr8_102832869_-intronic
CAediting_655277chr8_102832874_-intronic
CAediting_655278chr8_102833053_-intronic
CAediting_655279chr8_102833659_-intronic
CAediting_655280chr8_102833686_-intronic
CAediting_655281chr8_102833718_-intronic
CAediting_655282chr8_102833739_-intronic
CAediting_655283chr8_102833814_-intronic
CAediting_655284chr8_102833815_-intronic
CAediting_655285chr8_102840403_-ncRNA_intronic
CAediting_655286chr8_102840416_-ncRNA_intronic
CAediting_655287chr8_102840447_-ncRNA_intronic
CAediting_655288chr8_102840489_-ncRNA_intronic
CAediting_655289chr8_102840491_-ncRNA_intronic
CAediting_655290chr8_102842051_-ncRNA_intronic
CAediting_655291chr8_102842104_-ncRNA_intronic
CAediting_655292chr8_102842105_-ncRNA_intronic
CAediting_655293chr8_102842863_-ncRNA_intronic
CAediting_655294chr8_102844296_-ncRNA_intronic
CAediting_655295chr8_102847736_-ncRNA_intronic
CAediting_655296chr8_102847764_-ncRNA_intronic
CAediting_655297chr8_102847793_-ncRNA_intronic
CAediting_655298chr8_102848519_-ncRNA_intronic
CAediting_655299chr8_102848529_-ncRNA_intronic
CAediting_655300chr8_102849210_-ncRNA_intronic
CAediting_655301chr8_102851464_-ncRNA_intronic
CAediting_655302chr8_102851473_-ncRNA_intronic
CAediting_655303chr8_102851514_-ncRNA_intronic
CAediting_655304chr8_102851637_-ncRNA_intronic
CAediting_655305chr8_102851643_-ncRNA_intronic
CAediting_655306chr8_102851644_-ncRNA_intronic
CAediting_655307chr8_102853242_-ncRNA_intronic
CAediting_655308chr8_102853248_-ncRNA_intronic
CAediting_655309chr8_102853254_-ncRNA_intronic
CAediting_655310chr8_102853260_-ncRNA_intronic
CAediting_655311chr8_102853318_-ncRNA_intronic
CAediting_655312chr8_102853323_-ncRNA_intronic
CAediting_655313chr8_102853337_-ncRNA_intronic
CAediting_655314chr8_102853380_-ncRNA_intronic
CAediting_655315chr8_102853450_-ncRNA_intronic
CAediting_655316chr8_102853471_-ncRNA_intronic
CAediting_655317chr8_102853501_-ncRNA_intronic
CAediting_655318chr8_102853984_-ncRNA_intronic
CAediting_655319chr8_102854009_-ncRNA_intronic
CAediting_655320chr8_102854014_-ncRNA_intronic
CAediting_655321chr8_102854018_-ncRNA_intronic
CAediting_655322chr8_102854067_-ncRNA_intronic
CAediting_655323chr8_102854072_-ncRNA_intronic
CAediting_655324chr8_102854073_-ncRNA_intronic
CAediting_655325chr8_102854099_-ncRNA_intronic
CAediting_655326chr8_102854181_-ncRNA_intronic
CAediting_655327chr8_102854214_-ncRNA_intronic
CAediting_655328chr8_102854218_-ncRNA_intronic
CAediting_655329chr8_102854408_-ncRNA_intronic
CAediting_655330chr8_102854419_-ncRNA_intronic
CAediting_655331chr8_102861313_-ncRNA_intronic
CAediting_655332chr8_102861325_-ncRNA_intronic
CAediting_655333chr8_102861783_-ncRNA_intronic
CAediting_655334chr8_102861868_-ncRNA_intronic
CAediting_655335chr8_102861869_-ncRNA_intronic
CAediting_655336chr8_102861870_-ncRNA_intronic
CAediting_655337chr8_102861873_-ncRNA_intronic
CAediting_655338chr8_102861914_-ncRNA_intronic
CAediting_655339chr8_102861936_-ncRNA_intronic
CAediting_655340chr8_102861954_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_655261chr8_102830135_-SINEAluAluSz6
CAediting_655262chr8_102830141_-SINEAluAluSz6
CAediting_655263chr8_102830156_-SINEAluAluSz6
CAediting_655264chr8_102830258_-SINEAluAluSz6
CAediting_655265chr8_102830264_-SINEAluAluSz6
CAediting_655266chr8_102830278_-SINEAluAluSz6
CAediting_655267chr8_102830294_-SINEAluAluSz6
CAediting_655268chr8_102830639_-SINEAluAluYg6
CAediting_655269chr8_102831535_-SINEAluAluSq
CAediting_655270chr8_102831586_-SINEAluAluSq
CAediting_655271chr8_102832749_-SINEAluAluSx4
CAediting_655272chr8_102832778_-SINEAluAluSx4
CAediting_655273chr8_102832785_-SINEAluAluSx4
CAediting_655274chr8_102832805_-SINEAluAluSx4
CAediting_655275chr8_102832834_-SINEAluAluSx4
CAediting_655276chr8_102832869_-SINEAluAluSx4
CAediting_655277chr8_102832874_-SINEAluAluSx4
CAediting_655279chr8_102833659_-SINEAluAluJr4
CAediting_655280chr8_102833686_-SINEAluAluJr4
CAediting_655281chr8_102833718_-SINEAluAluJr4
CAediting_655282chr8_102833739_-SINEAluAluJr4
CAediting_655283chr8_102833814_-SINEAluAluJr4
CAediting_655284chr8_102833815_-SINEAluAluJr4
CAediting_655285chr8_102840403_-SINEAluFRAM
CAediting_655286chr8_102840416_-SINEAluFRAM
CAediting_655287chr8_102840447_-SINEAluFRAM
CAediting_655288chr8_102840489_-SINEAluFRAM
CAediting_655289chr8_102840491_-SINEAluFRAM
CAediting_655290chr8_102842051_-SINEAluAluSq
CAediting_655291chr8_102842104_-SINEAluAluSq
CAediting_655292chr8_102842105_-SINEAluAluSq
CAediting_655293chr8_102842863_-SINEAluAluSz6
CAediting_655294chr8_102844296_-SINEAluFLAM_C
CAediting_655295chr8_102847736_-SINEAluAluJr
CAediting_655296chr8_102847764_-SINEAluAluJr
CAediting_655297chr8_102847793_-SINEAluAluJr
CAediting_655298chr8_102848519_-SINEAluFLAM_C
CAediting_655299chr8_102848529_-SINEAluFLAM_C
CAediting_655300chr8_102849210_-SINEAluAluSc
CAediting_655301chr8_102851464_-SINEAluAluSg4
CAediting_655302chr8_102851473_-SINEAluAluSg4
CAediting_655303chr8_102851514_-SINEAluAluSg4
CAediting_655304chr8_102851637_-SINEAluAluSg4
CAediting_655305chr8_102851643_-SINEAluAluSg4
CAediting_655306chr8_102851644_-SINEAluAluSg4
CAediting_655307chr8_102853242_-SINEAluAluSq
CAediting_655308chr8_102853248_-SINEAluAluSq
CAediting_655309chr8_102853254_-SINEAluAluSq
CAediting_655310chr8_102853260_-SINEAluAluSq
CAediting_655311chr8_102853318_-SINEAluAluSq
CAediting_655312chr8_102853323_-SINEAluAluSq
CAediting_655313chr8_102853337_-SINEAluAluSq
CAediting_655314chr8_102853380_-SINEAluAluSq
CAediting_655315chr8_102853450_-SINEAluAluSq
CAediting_655316chr8_102853471_-SINEAluAluSq
CAediting_655317chr8_102853501_-SINEAluAluSq
CAediting_655318chr8_102853984_-SINEAluAluSx
CAediting_655319chr8_102854009_-SINEAluAluSx
CAediting_655320chr8_102854014_-SINEAluAluSx
CAediting_655321chr8_102854018_-SINEAluAluSx
CAediting_655322chr8_102854067_-SINEAluAluSx
CAediting_655323chr8_102854072_-SINEAluAluSx
CAediting_655324chr8_102854073_-SINEAluAluSx
CAediting_655325chr8_102854099_-SINEAluAluSx
CAediting_655326chr8_102854181_-SINEAluAluSx
CAediting_655327chr8_102854214_-SINEAluAluSx
CAediting_655328chr8_102854218_-SINEAluAluSx
CAediting_655329chr8_102854408_-SINEAluAluSx1
CAediting_655330chr8_102854419_-SINEAluAluSx1
CAediting_655331chr8_102861313_-SINEAluAluSq10
CAediting_655332chr8_102861325_-SINEAluAluSq10
CAediting_655333chr8_102861783_-SINEAluAluSx1
CAediting_655334chr8_102861868_-SINEAluAluSx1
CAediting_655335chr8_102861869_-SINEAluAluSx1
CAediting_655336chr8_102861870_-SINEAluAluSx1
CAediting_655337chr8_102861873_-SINEAluAluSx1
CAediting_655338chr8_102861914_-SINEAluAluSx1
CAediting_655339chr8_102861936_-SINEAluAluSx1
CAediting_655340chr8_102861954_-SINEAluAluSx1

Top

RNA A-to-I editing events in the alternative splicing sites for AZIN1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_655278chr8_102833053_-102833049:1028330575SS0+2iAGGTAAGTT-14.09AGGTGAGTT-13.56

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000155096.12.AZIN1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000155096.12.AZIN1.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for AZIN1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
TGCT.CAediting_655260.ENSG00000155096.AZIN1.png
Soverview

Top

Protein coding region RNA A-to-I editings for AZIN1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


Top

The effects of the RNA editing to the miRNA binding sites for AZIN1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for AZIN1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000337198.8protein_codingSoverviewSoverview
ENST00000347770.7protein_codingSoverviewSoverview
ENST00000518697.1processed_transcriptSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_655260ENST00000337198.8chr8_102829408_--1429.74-1430.04-1429.74
CAediting_655260ENST00000347770.7chr8_102829408_--806.40-806.70-806.40
CAediting_655260ENST00000518697.1chr8_102829408_--177.40-177.70-181.70
CAediting_655261ENST00000518697.1chr8_102830135_--178.10-177.70-181.70
CAediting_655262ENST00000518697.1chr8_102830141_--182.70-177.70-181.70
CAediting_655263ENST00000518697.1chr8_102830156_--177.30-177.70-181.70

Top

Relation with ADAR for AZIN1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BLCACAediting_655260chr8_102829408_-0.0001593145743015690.311704815480444....
LGGCAediting_655260chr8_102829408_-5.15531970234642e-090.565631317587958....
BRCACAediting_655260chr8_102829408_-9.77068013305059e-610.574256631975044....
LIHCCAediting_655260chr8_102829408_-1.90649690194271e-120.407850291855416....
CESCCAediting_655260chr8_102829408_-0.0007372841703788570.338688661076645....
LUADCAediting_655260chr8_102829408_-5.16084651272511e-210.493137215582475....
COADCAediting_655260chr8_102829408_-0.02403667852853690.213157759917836....
LUSCCAediting_655260chr8_102829408_-4.05566446804916e-150.502908619420333..0.03129315556749070.147257317154137
PRADCAediting_655260chr8_102829408_-2.4649353287269e-090.591731174275164....
HNSCCAediting_655260chr8_102829408_-2.56265249645306e-050.304961105114429....
STADCAediting_655260chr8_102829408_-5.06602734649645e-050.311867638529529....
THCACAediting_655260chr8_102829408_-1.41340113785235e-050.322628988187403....
KIRCCAediting_655260chr8_102829408_-0.0006606473162844920.195849687299039....
UCECCAediting_655260chr8_102829408_-1.41902835877216e-100.437617097650058....
ESCACAediting_655260chr8_102829408_-0.0001520442206827710.42107370865425....
OVCAediting_655260chr8_102829408_-4.81854754276514e-060.295699943952791....
PAADCAediting_655260chr8_102829408_-9.37840137335577e-060.462665602044439....
PCPGCAediting_655260chr8_102829408_-0.01622763800699760.280506310326541....
SKCMCAediting_655260chr8_102829408_-0.001972366329813910.298631329366883....
SARCCAediting_655260chr8_102829408_-2.7614605927613e-060.44715506249048....
TGCTCAediting_655260chr8_102829408_-3.31367796560452e-110.639829771521034....

Top

Relation with cancer stages for AZIN1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
SKCMpathologic_stageCAediting_655260chr8_102829408_-0.0029298225175184-0.305224573843284
THCApathologic_stageCAediting_655260chr8_102829408_-0.007823566228340190.202167670380044

Top

Relation with survival for AZIN1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LGGCAediting_655260chr8_102829408_-0.01430254395190890.0172116473.593

Top

RelatedDrugs for AZIN1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for AZIN1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource