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Editing gene: NCKIPSD (CAeditome ID:51517)

Gene summary for NCKIPSD

Gene summary

Gene information	Gene symbol	NCKIPSD
	Gene ID	51517
	Gene name	NCK interacting protein with SH3 domain
	Synonyms	AF3P21\|DIP\|DIP1\|ORF1\|SPIN90\|VIP54\|WASLBP\|WISH
	Cytomap	3p21.31
	Type of gene	protein-coding
	Description	NCK-interacting protein with SH3 domain54 kDa VacA-interacting protein54 kDa vimentin-interacting protein90 kDa SH3 protein interacting with NckSH3 adapter protein SPIN90SH3 protein interacting with Nck, 90 kDaWASP-interacting SH3-domain proteindia
	Modification date	20210518
	UniProtAcc	Q9NZQ3
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for NCKIPSD

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000213672.6

RNA A-to-I editing events in Cancer.

CAediting_275975(48675609, -), CAediting_275976(48675627, -), CAediting_275977(48675679, -), CAediting_275978(48675680, -), CAediting_275979(48675698, -), CAediting_275980(48675702, -), CAediting_275981(48675715, -), CAediting_275982(48675739, -), CAediting_275983(48675759, -), CAediting_275984(48675762, -), CAediting_275985(48675763, -), CAediting_275986(48676515, -), CAediting_275987(48676553, -), CAediting_275988(48676564, -), CAediting_275989(48676573, -), CAediting_275990(48676578, -), CAediting_275991(48676583, -), CAediting_275992(48676595, -), CAediting_275993(48676596, -), CAediting_275994(48676609, -), CAediting_275995(48676612, -), CAediting_275996(48676613, -), CAediting_275997(48676618, -), CAediting_275998(48676619, -), CAediting_275999(48676629, -), CAediting_276000(48676637, -), CAediting_276001(48676692, -), CAediting_276002(48676711, -), CAediting_276003(48676730, -), CAediting_276004(48676742, -), CAediting_276005(48676749, -), CAediting_276006(48676757, -), CAediting_276007(48676765, -), CAediting_276008(48676766, -), CAediting_276009(48676774, -), CAediting_276010(48676831, -), CAediting_276011(48676833, -), CAediting_276012(48676838, -), CAediting_276013(48676839, -), CAediting_276014(48676843, -), CAediting_276015(48676867, -), CAediting_276016(48676868, -), CAediting_276017(48676882, -), CAediting_276018(48676886, -), CAediting_276019(48676899, -), CAediting_276020(48676903, -), CAediting_276021(48676909, -), CAediting_276022(48676927, -), CAediting_276023(48676935, -), CAediting_276024(48676938, -), CAediting_276025(48676939, -), CAediting_276026(48676940, -), CAediting_276027(48676941, -), CAediting_276028(48676944, -), CAediting_276029(48676993, -), CAediting_276030(48677001, -), CAediting_276031(48677004, -), CAediting_276032(48677009, -), CAediting_276033(48677014, -), CAediting_276034(48677044, -), CAediting_276035(48677049, -), CAediting_276036(48677050, -), CAediting_276037(48677130, -), CAediting_276038(48677132, -), CAediting_276039(48677167, -), CAediting_276040(48677168, -), CAediting_276041(48677172, -), CAediting_276042(48677177, -), CAediting_276043(48677223, -), CAediting_276044(48677226, -), CAediting_276045(48677239, -), CAediting_276046(48677248, -), CAediting_276047(48677264, -), CAediting_276048(48677266, -), CAediting_276049(48677288, -), CAediting_276050(48677305, -), CAediting_276051(48677306, -), CAediting_276052(48677325, -), CAediting_276053(48677331, -), CAediting_276054(48677341, -), CAediting_276055(48677344, -), CAediting_276056(48677362, -), CAediting_276057(48677363, -),

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RNA editing positional annotations for NCKIPSD using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_275975	chr3_48675609_-	ncRNA_intronic
CAediting_275976	chr3_48675627_-	ncRNA_intronic
CAediting_275977	chr3_48675679_-	ncRNA_intronic
CAediting_275978	chr3_48675680_-	ncRNA_intronic
CAediting_275979	chr3_48675698_-	ncRNA_intronic
CAediting_275980	chr3_48675702_-	ncRNA_intronic
CAediting_275981	chr3_48675715_-	ncRNA_intronic
CAediting_275982	chr3_48675739_-	ncRNA_intronic
CAediting_275983	chr3_48675759_-	ncRNA_intronic
CAediting_275984	chr3_48675762_-	ncRNA_intronic
CAediting_275985	chr3_48675763_-	ncRNA_intronic
CAediting_275986	chr3_48676515_-	ncRNA_intronic
CAediting_275987	chr3_48676553_-	ncRNA_intronic
CAediting_275988	chr3_48676564_-	ncRNA_intronic
CAediting_275989	chr3_48676573_-	ncRNA_intronic
CAediting_275990	chr3_48676578_-	ncRNA_intronic
CAediting_275991	chr3_48676583_-	ncRNA_intronic
CAediting_275992	chr3_48676595_-	ncRNA_intronic
CAediting_275993	chr3_48676596_-	ncRNA_intronic
CAediting_275994	chr3_48676609_-	ncRNA_intronic
CAediting_275995	chr3_48676612_-	ncRNA_intronic
CAediting_275996	chr3_48676613_-	ncRNA_intronic
CAediting_275997	chr3_48676618_-	ncRNA_intronic
CAediting_275998	chr3_48676619_-	ncRNA_intronic
CAediting_275999	chr3_48676629_-	ncRNA_intronic
CAediting_276000	chr3_48676637_-	ncRNA_intronic
CAediting_276001	chr3_48676692_-	ncRNA_intronic
CAediting_276002	chr3_48676711_-	ncRNA_intronic
CAediting_276003	chr3_48676730_-	ncRNA_intronic
CAediting_276004	chr3_48676742_-	ncRNA_intronic
CAediting_276005	chr3_48676749_-	ncRNA_intronic
CAediting_276006	chr3_48676757_-	ncRNA_intronic
CAediting_276007	chr3_48676765_-	ncRNA_intronic
CAediting_276008	chr3_48676766_-	ncRNA_intronic
CAediting_276009	chr3_48676774_-	ncRNA_intronic
CAediting_276010	chr3_48676831_-	ncRNA_intronic
CAediting_276011	chr3_48676833_-	ncRNA_intronic
CAediting_276012	chr3_48676838_-	ncRNA_intronic
CAediting_276013	chr3_48676839_-	ncRNA_intronic
CAediting_276014	chr3_48676843_-	ncRNA_intronic
CAediting_276015	chr3_48676867_-	ncRNA_intronic
CAediting_276016	chr3_48676868_-	ncRNA_intronic
CAediting_276017	chr3_48676882_-	ncRNA_intronic
CAediting_276018	chr3_48676886_-	ncRNA_intronic
CAediting_276019	chr3_48676899_-	ncRNA_intronic
CAediting_276020	chr3_48676903_-	ncRNA_intronic
CAediting_276021	chr3_48676909_-	ncRNA_intronic
CAediting_276022	chr3_48676927_-	ncRNA_intronic
CAediting_276023	chr3_48676935_-	ncRNA_intronic
CAediting_276024	chr3_48676938_-	ncRNA_intronic
CAediting_276025	chr3_48676939_-	ncRNA_intronic
CAediting_276026	chr3_48676940_-	ncRNA_intronic
CAediting_276027	chr3_48676941_-	ncRNA_intronic
CAediting_276028	chr3_48676944_-	ncRNA_intronic
CAediting_276029	chr3_48676993_-	ncRNA_intronic
CAediting_276030	chr3_48677001_-	ncRNA_intronic
CAediting_276031	chr3_48677004_-	ncRNA_intronic
CAediting_276032	chr3_48677009_-	ncRNA_intronic
CAediting_276033	chr3_48677014_-	ncRNA_intronic
CAediting_276034	chr3_48677044_-	ncRNA_intronic
CAediting_276035	chr3_48677049_-	ncRNA_intronic
CAediting_276036	chr3_48677050_-	ncRNA_intronic
CAediting_276037	chr3_48677130_-	ncRNA_intronic
CAediting_276038	chr3_48677132_-	ncRNA_intronic
CAediting_276039	chr3_48677167_-	ncRNA_intronic
CAediting_276040	chr3_48677168_-	ncRNA_intronic
CAediting_276041	chr3_48677172_-	ncRNA_intronic
CAediting_276042	chr3_48677177_-	ncRNA_intronic
CAediting_276043	chr3_48677223_-	ncRNA_intronic
CAediting_276044	chr3_48677226_-	ncRNA_intronic
CAediting_276045	chr3_48677239_-	ncRNA_intronic
CAediting_276046	chr3_48677248_-	ncRNA_intronic
CAediting_276047	chr3_48677264_-	ncRNA_intronic
CAediting_276048	chr3_48677266_-	ncRNA_intronic
CAediting_276049	chr3_48677288_-	ncRNA_intronic
CAediting_276050	chr3_48677305_-	ncRNA_intronic
CAediting_276051	chr3_48677306_-	ncRNA_intronic
CAediting_276052	chr3_48677325_-	ncRNA_intronic
CAediting_276053	chr3_48677331_-	ncRNA_intronic
CAediting_276054	chr3_48677341_-	ncRNA_intronic
CAediting_276055	chr3_48677344_-	ncRNA_intronic
CAediting_276056	chr3_48677362_-	ncRNA_intronic
CAediting_276057	chr3_48677363_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_275975	chr3_48675609_-	SINE	Alu	AluSz
CAediting_275976	chr3_48675627_-	SINE	Alu	AluSz
CAediting_275977	chr3_48675679_-	SINE	Alu	AluSz
CAediting_275978	chr3_48675680_-	SINE	Alu	AluSz
CAediting_275979	chr3_48675698_-	SINE	Alu	AluSz
CAediting_275980	chr3_48675702_-	SINE	Alu	AluSz
CAediting_275981	chr3_48675715_-	SINE	Alu	AluSz
CAediting_275982	chr3_48675739_-	SINE	Alu	AluSz
CAediting_275983	chr3_48675759_-	SINE	Alu	AluSz
CAediting_275984	chr3_48675762_-	SINE	Alu	AluSz
CAediting_275985	chr3_48675763_-	SINE	Alu	AluSz
CAediting_275986	chr3_48676515_-	SINE	Alu	AluJb
CAediting_275987	chr3_48676553_-	SINE	Alu	AluJb
CAediting_275988	chr3_48676564_-	SINE	Alu	AluJb
CAediting_275989	chr3_48676573_-	SINE	Alu	AluJb
CAediting_275990	chr3_48676578_-	SINE	Alu	AluJb
CAediting_275991	chr3_48676583_-	SINE	Alu	AluJb
CAediting_275992	chr3_48676595_-	SINE	Alu	AluJb
CAediting_275993	chr3_48676596_-	SINE	Alu	AluJb
CAediting_275994	chr3_48676609_-	SINE	Alu	AluJb
CAediting_275995	chr3_48676612_-	SINE	Alu	AluJb
CAediting_275996	chr3_48676613_-	SINE	Alu	AluJb
CAediting_275997	chr3_48676618_-	SINE	Alu	AluJb
CAediting_275998	chr3_48676619_-	SINE	Alu	AluJb
CAediting_275999	chr3_48676629_-	SINE	Alu	AluJb
CAediting_276000	chr3_48676637_-	SINE	Alu	AluJb
CAediting_276001	chr3_48676692_-	SINE	Alu	AluJb
CAediting_276002	chr3_48676711_-	SINE	Alu	AluJb
CAediting_276003	chr3_48676730_-	SINE	Alu	AluJb
CAediting_276004	chr3_48676742_-	SINE	Alu	AluJb
CAediting_276005	chr3_48676749_-	SINE	Alu	AluJb
CAediting_276006	chr3_48676757_-	SINE	Alu	AluJb
CAediting_276007	chr3_48676765_-	SINE	Alu	AluJb
CAediting_276008	chr3_48676766_-	SINE	Alu	AluJb
CAediting_276009	chr3_48676774_-	SINE	Alu	AluJb
CAediting_276010	chr3_48676831_-	SINE	Alu	AluSx1
CAediting_276011	chr3_48676833_-	SINE	Alu	AluSx1
CAediting_276012	chr3_48676838_-	SINE	Alu	AluSx1
CAediting_276013	chr3_48676839_-	SINE	Alu	AluSx1
CAediting_276014	chr3_48676843_-	SINE	Alu	AluSx1
CAediting_276015	chr3_48676867_-	SINE	Alu	AluSx1
CAediting_276016	chr3_48676868_-	SINE	Alu	AluSx1
CAediting_276017	chr3_48676882_-	SINE	Alu	AluSx1
CAediting_276018	chr3_48676886_-	SINE	Alu	AluSx1
CAediting_276019	chr3_48676899_-	SINE	Alu	AluSx1
CAediting_276020	chr3_48676903_-	SINE	Alu	AluSx1
CAediting_276021	chr3_48676909_-	SINE	Alu	AluSx1
CAediting_276022	chr3_48676927_-	SINE	Alu	AluSx1
CAediting_276023	chr3_48676935_-	SINE	Alu	AluSx1
CAediting_276024	chr3_48676938_-	SINE	Alu	AluSx1
CAediting_276025	chr3_48676939_-	SINE	Alu	AluSx1
CAediting_276026	chr3_48676940_-	SINE	Alu	AluSx1
CAediting_276027	chr3_48676941_-	SINE	Alu	AluSx1
CAediting_276028	chr3_48676944_-	SINE	Alu	AluSx1
CAediting_276029	chr3_48676993_-	SINE	Alu	AluSx1
CAediting_276030	chr3_48677001_-	SINE	Alu	AluSx1
CAediting_276031	chr3_48677004_-	SINE	Alu	AluSx1
CAediting_276032	chr3_48677009_-	SINE	Alu	AluSx1
CAediting_276033	chr3_48677014_-	SINE	Alu	AluSx1
CAediting_276034	chr3_48677044_-	SINE	Alu	AluSx1
CAediting_276035	chr3_48677049_-	SINE	Alu	AluSx1
CAediting_276036	chr3_48677050_-	SINE	Alu	AluSx1
CAediting_276037	chr3_48677130_-	SINE	Alu	AluSx1
CAediting_276038	chr3_48677132_-	SINE	Alu	AluSx1
CAediting_276039	chr3_48677167_-	SINE	Alu	AluSx1
CAediting_276040	chr3_48677168_-	SINE	Alu	AluSx1
CAediting_276041	chr3_48677172_-	SINE	Alu	AluSx1
CAediting_276042	chr3_48677177_-	SINE	Alu	AluSx1
CAediting_276043	chr3_48677223_-	SINE	Alu	AluSx1
CAediting_276044	chr3_48677226_-	SINE	Alu	AluSx1
CAediting_276045	chr3_48677239_-	SINE	Alu	AluSx1
CAediting_276046	chr3_48677248_-	SINE	Alu	AluSx1
CAediting_276047	chr3_48677264_-	SINE	Alu	AluSx1
CAediting_276048	chr3_48677266_-	SINE	Alu	AluSx1
CAediting_276049	chr3_48677288_-	SINE	Alu	AluSx1
CAediting_276050	chr3_48677305_-	SINE	Alu	AluSx1
CAediting_276051	chr3_48677306_-	SINE	Alu	AluSx1
CAediting_276052	chr3_48677325_-	SINE	Alu	AluSx1
CAediting_276053	chr3_48677331_-	SINE	Alu	AluSx1
CAediting_276054	chr3_48677341_-	SINE	Alu	AluSx1
CAediting_276055	chr3_48677344_-	SINE	Alu	AluSx1
CAediting_276056	chr3_48677362_-	SINE	Alu	AluSx1
CAediting_276057	chr3_48677363_-	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for NCKIPSD

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000213672.6.NCKIPSD.

Correlation between RNA A-to-I editing and PSI for ENSG00000213672.6.NCKIPSD.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NCKIPSD

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for NCKIPSD

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for NCKIPSD

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000213672.6	ENST00000454134	hsa-miR-624-3p	48682521	48682527	7mer-m8	48682520	48682540	143	-15.61
CAediting_748296	chr10_51299626_+	ENSG00000213672.6	ENST00000454134	hsa-miR-605-3p	48681759	48681765	7mer-m8	48681758	48681779	141	-13.79
CAediting_1368054	chr19_46709310_-	ENSG00000213672.6	ENST00000416649	hsa-miR-320e	48674135	48674141	7mer-m8	48674134	48674151	151	-20.75
CAediting_86358	chr1_109598906_+	ENSG00000213672.6	ENST00000416649	hsa-miR-197-5p	48674082	48674088	7mer-m8	48674081	48674105	161	-34.72
CAediting_1368054	chr19_46709310_-	ENSG00000213672.6	ENST00000294129	hsa-miR-320e	48674135	48674141	7mer-m8	48674134	48674151	151	-20.75
CAediting_86358	chr1_109598906_+	ENSG00000213672.6	ENST00000294129	hsa-miR-197-5p	48674082	48674088	7mer-m8	48674081	48674105	161	-34.72
CAediting_1399425	chr20_1392958_-	ENSG00000213672.6	ENST00000454134	hsa-miR-6869-5p	48682386	48682392	7mer-m8	48682385	48682408	149	-21.47
CAediting_1368054	chr19_46709310_-	ENSG00000213672.6	ENST00000454134	hsa-miR-320e	48681690	48681696	7mer-m8	48681689	48681707	149	-17.89
CAediting_604450	chr7_133034877_-	ENSG00000213672.6	ENST00000454134	hsa-miR-3654	48681601	48681607	7mer-m8	48681600	48681618	140	-19.85
CAediting_604450	chr7_133034877_-	ENSG00000213672.6	ENST00000454134	hsa-miR-3654	48681737	48681743	7mer-m8	48681736	48681752	149	-18.56
CAediting_1524209	chrX_134546392_-	ENSG00000213672.6	ENST00000416649	hsa-miR-503-5p	48674063	48674069	7mer-m8	48674062	48674083	143	-18.2
CAediting_1524209	chrX_134546392_-	ENSG00000213672.6	ENST00000294129	hsa-miR-503-5p	48674063	48674069	7mer-m8	48674062	48674083	143	-18.2

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NCKIPSD

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for NCKIPSD

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for NCKIPSD

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for NCKIPSD

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for NCKIPSD

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for NCKIPSD

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene