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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: MEX3C (CAeditome ID:51320) |
Gene summary for MEX3C |
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Gene information | Gene symbol | MEX3C | Gene ID | 51320 |
Gene name | mex-3 RNA binding family member C | |
Synonyms | BM-013|MEX-3C|RKHD2|RNF194 | |
Cytomap | 18q21.2 | |
Type of gene | protein-coding | |
Description | RNA-binding E3 ubiquitin-protein ligase MEX3CMEX3C variant 1MEX3C variant 2RING finger and KH domain-containing protein 2RING finger protein 194RING-type E3 ubiquitin transferase MEX3CRNA-binding protein MEX3Cring finger and KH domain containing 2 | |
Modification date | 20210518 | |
UniProtAcc | Q5U5Q3 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
MEX3C | GO:0003723 | RNA-binding E3 ubiquitin-protein ligase MEX3C | 23408853 |
MEX3C | GO:0061630 | RNA-binding E3 ubiquitin-protein ligase MEX3C | 22863774 |
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RNA A-to-I events for MEX3C |
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CAediting_1264829(51197099, -), |
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RNA editing positional annotations for MEX3C using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_1264829 | chr18_51197099_- | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for MEX3C |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MEX3C |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for MEX3C |
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The effects of the RNA editing to the miRNA binding sites for MEX3C |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_980496 | chr14_31014685_- | ENSG00000176624.10 | ENST00000592416 | hsa-miR-624-3p | 51193207 | 51193213 | 7mer-m8 | 51193206 | 51193227 | 146 | -11.73 |
CAediting_393 | chr1_1167164_+ | ENSG00000176624.10 | ENST00000592416 | hsa-miR-200b-3p | 51195652 | 51195657 | 6mer | 51195651 | 51195670 | 144 | -12.71 |
CAediting_1229413 | chr17_67471544_+ | ENSG00000176624.10 | ENST00000592416 | hsa-miR-548aa | 51195443 | 51195450 | 8mer-1a | 51195443 | 51195467 | 159 | -13.34 |
CAediting_1229414 | chr17_67471546_+ | ENSG00000176624.10 | ENST00000592416 | hsa-miR-548aa | 51192979 | 51192985 | 7mer-m8 | 51192978 | 51193002 | 159 | -13.86 |
CAediting_468389 | chr6_31355314_- | ENSG00000176624.10 | ENST00000592416 | hsa-miR-6891-5p | 51195824 | 51195829 | 6mer | 51195820 | 51195838 | 144 | -20.54 |
CAediting_1524209 | chrX_134546392_- | ENSG00000176624.10 | ENST00000592416 | hsa-miR-503-5p | 51195615 | 51195621 | 7mer-1a | 51195615 | 51195636 | 157 | -31.49 |
CAediting_1524209 | chrX_134546392_- | ENSG00000176624.10 | ENST00000592416 | hsa-miR-503-5p | 51195517 | 51195523 | 7mer-m8 | 51195516 | 51195538 | 159 | -20.98 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_393 | chr1_1167164_+ | ENSG00000176624.10 | ENST00000406189 | hsa-miR-200b-3p | 51174774 | 51174779 | 6mer | 51174773 | 51174794 | 144 | -11.81 |
CAediting_393 | chr1_1167164_+ | ENSG00000176624.10 | ENST00000592416 | hsa-miR-200b-3p | 51194114 | 51194121 | 8mer-1a | 51194114 | 51194135 | 150 | -13.08 |
CAediting_396018 | chr5_1062918_- | ENSG00000176624.10 | ENST00000592416 | hsa-miR-4635 | 51193044 | 51193050 | 7mer-m8 | 51193043 | 51193063 | 143 | -14.41 |
CAediting_396018 | chr5_1062918_- | ENSG00000176624.10 | ENST00000592416 | hsa-miR-4635 | 51192954 | 51192960 | 7mer-m8 | 51192953 | 51192973 | 150 | -12.19 |
CAediting_1229413 | chr17_67471544_+ | ENSG00000176624.10 | ENST00000592416 | hsa-miR-548aa | 51195235 | 51195241 | 7mer-m8 | 51195234 | 51195260 | 148 | -10.67 |
CAediting_1229414 | chr17_67471546_+ | ENSG00000176624.10 | ENST00000592416 | hsa-miR-548aa | 51195235 | 51195241 | 7mer-m8 | 51195234 | 51195260 | 148 | -10.67 |
CAediting_228905 | chr2_188297554_+ | ENSG00000176624.10 | ENST00000592416 | hsa-miR-561-3p | 51195199 | 51195205 | 7mer-m8 | 51195198 | 51195217 | 148 | -10.3 |
CAediting_228905 | chr2_188297554_+ | ENSG00000176624.10 | ENST00000592416 | hsa-miR-561-3p | 51194600 | 51194607 | 8mer-1a | 51194600 | 51194621 | 140 | -4.07 |
CAediting_524911 | chr7_5495852_- | ENSG00000176624.10 | ENST00000592416 | hsa-miR-589-3p | 51194249 | 51194256 | 8mer-1a | 51194249 | 51194272 | 140 | -20.33 |
CAediting_980496 | chr14_31014685_- | ENSG00000176624.10 | ENST00000592416 | hsa-miR-624-3p | 51194334 | 51194341 | 8mer-1a | 51194334 | 51194354 | 146 | -11.15 |
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The effects of the RNA editing to the stability of the RNA structures for MEX3C |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for MEX3C |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for MEX3C |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for MEX3C |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for MEX3C |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MEX3C |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
MEX3C | C0004238 | Atrial Fibrillation | 2 | CTD_human |
MEX3C | C0235480 | Paroxysmal atrial fibrillation | 2 | CTD_human |
MEX3C | C2585653 | Persistent atrial fibrillation | 2 | CTD_human |
MEX3C | C3468561 | familial atrial fibrillation | 2 | CTD_human |
MEX3C | C0087031 | Juvenile-Onset Still Disease | 1 | CTD_human |
MEX3C | C3495559 | Juvenile arthritis | 1 | CTD_human |
MEX3C | C3714758 | Juvenile psoriatic arthritis | 1 | CTD_human |
MEX3C | C4552091 | Polyarthritis, Juvenile, Rheumatoid Factor Negative | 1 | CTD_human |
MEX3C | C4704862 | Polyarthritis, Juvenile, Rheumatoid Factor Positive | 1 | CTD_human |