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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: MRPL35 (CAeditome ID:51318) |
Gene summary for MRPL35 |
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Gene information | Gene symbol | MRPL35 | Gene ID | 51318 |
Gene name | mitochondrial ribosomal protein L35 | |
Synonyms | L35mt|MRP-L35 | |
Cytomap | 2p11.2 | |
Type of gene | protein-coding | |
Description | 39S ribosomal protein L35, mitochondrialmitochondrial large ribosomal subunit protein bL35m | |
Modification date | 20210518 | |
UniProtAcc | Q9NZE8 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
MRPL35 | GO:0005739 | 39S ribosomal protein L35, mitochondrial | 28892042 |
MRPL35 | GO:0005762 | 39S ribosomal protein L35, mitochondrial | 25278503 |
MRPL35 | GO:0005762 | 39S ribosomal protein L35, mitochondrial | 28892042 |
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RNA A-to-I events for MRPL35 |
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CAediting_197807(86210558, +), CAediting_197808(86211460, +), CAediting_197809(86211790, +), |
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RNA editing positional annotations for MRPL35 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_197807 | chr2_86210558_+ | nonsynonymous SNV | ENST00000254644.11 | c.A457G | p.T153A | D | D | D |
CAediting_197807 | chr2_86210558_+ | nonsynonymous SNV | ENST00000337109.7 | c.A457G | p.T153A | D | D | D |
CAediting_197807 | chr2_86210558_+ | nonsynonymous SNV | ENST00000409180.1 | c.A457G | p.T153A | D | D | D |
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CAeditome ID | Position | Variant type |
CAediting_197807 | chr2_86210558_+ | exonic |
CAediting_197808 | chr2_86211460_+ | UTR3 |
CAediting_197809 | chr2_86211790_+ | UTR3 |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_197809 | chr2_86211790_+ | SINE | Alu | AluJo |
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RNA A-to-I editing events in the alternative splicing sites for MRPL35 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRPL35 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for MRPL35 |
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The effects of the RNA editing to the miRNA binding sites for MRPL35 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_197807 | chr2_86210558_+ | ENSG00000132313.13 | ENST00000605125 | hsa-miR-6839-3p | 86210555 | 86210561 | 7mer-m8 | 86210542 | 86210562 | 150 | -11.29 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_228905 | chr2_188297554_+ | ENSG00000132313.13 | ENST00000605125 | hsa-miR-561-3p | 86210566 | 86210572 | 7mer-m8 | 86210552 | 86210573 | 145 | -9.3 |
CAediting_228905 | chr2_188297554_+ | ENSG00000132313.13 | ENST00000409180 | hsa-miR-561-3p | 86213701 | 86213708 | 8mer-1a | 86213687 | 86213708 | 148 | -6.74 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for MRPL35 |
![]() * Click on the image to enlarge it in a new window. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
CAediting_197807 | ENST00000254644.11 | chr2_86210558_+ | -303.20 | -303.20 | -303.20 |
CAediting_197807 | ENST00000337109.7 | chr2_86210558_+ | -990.77 | -989.97 | -991.17 |
CAediting_197808 | ENST00000337109.7 | chr2_86211460_+ | -989.97 | -989.97 | -991.17 |
CAediting_197809 | ENST00000337109.7 | chr2_86211790_+ | -990.37 | -989.97 | -991.17 |
CAediting_197807 | ENST00000409180.1 | chr2_86210558_+ | -177.60 | -177.20 | -177.60 |
CAediting_197807 | ENST00000605125.4 | chr2_86210558_+ | -196.90 | -196.10 | -196.90 |
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Relation with ADAR for MRPL35 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for MRPL35 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for MRPL35 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for MRPL35 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MRPL35 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |