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Editing gene: PDCL (CAeditome ID:5082)

Gene summary for PDCL

Gene summary

Gene information	Gene symbol	PDCL
	Gene ID	5082
	Gene name	phosducin like
	Synonyms	PhLP
	Cytomap	9q33.2
	Type of gene	protein-coding
	Description	phosducin-like protein
	Modification date	20210518
	UniProtAcc	Q13371
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
PDCL	GO:0005737	Phosducin-like protein	0000054

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RNA A-to-I events for PDCL

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000136940.12

RNA A-to-I editing events in Cancer.

CAediting_705676(122816283, -), CAediting_705677(122816293, -), CAediting_705678(122816305, -), CAediting_705679(122816399, -), CAediting_705680(122816403, -), CAediting_705681(122816415, -), CAediting_705682(122816418, -), CAediting_705683(122816419, -), CAediting_705684(122816422, -), CAediting_705685(122816443, -), CAediting_705686(122816448, -), CAediting_705687(122816472, -), CAediting_705688(122817166, -), CAediting_705689(122817169, -), CAediting_705690(122817173, -), CAediting_705691(122817175, -), CAediting_705692(122817187, -), CAediting_705693(122817219, -), CAediting_705694(122817248, -), CAediting_705695(122817263, -), CAediting_705696(122817268, -), CAediting_705697(122817274, -), CAediting_705698(122817282, -), CAediting_705699(122817283, -), CAediting_705700(122817293, -), CAediting_705701(122817307, -), CAediting_705702(122817319, -), CAediting_705703(122817331, -), CAediting_705704(122817344, -), CAediting_705705(122817347, -), CAediting_705706(122817349, -), CAediting_705707(122817368, -), CAediting_705708(122817369, -), CAediting_705709(122817374, -), CAediting_705710(122817384, -), CAediting_705711(122817387, -), CAediting_705712(122817395, -), CAediting_705713(122817427, -), CAediting_705714(122817429, -), CAediting_705715(122817505, -), CAediting_705716(122817520, -), CAediting_705717(122817522, -), CAediting_705718(122817535, -), CAediting_705719(122817552, -), CAediting_705720(122817564, -), CAediting_705721(122817565, -), CAediting_705722(122817578, -), CAediting_705723(122817586, -), CAediting_705724(122817589, -), CAediting_705725(122817592, -), CAediting_705726(122817602, -), CAediting_705727(122817609, -), CAediting_705728(122817613, -), CAediting_705729(122817619, -), CAediting_705730(122817625, -), CAediting_705731(122817635, -), CAediting_705732(122817646, -), CAediting_705733(122817647, -), CAediting_705734(122817648, -), CAediting_705735(122817650, -), CAediting_705736(122817651, -), CAediting_705737(122817653, -), CAediting_705738(122817656, -), CAediting_705739(122817657, -), CAediting_705740(122817658, -), CAediting_705741(122817659, -), CAediting_705742(122817660, -), CAediting_705743(122817662, -), CAediting_705744(122817668, -), CAediting_705745(122817675, -), CAediting_705746(122817681, -), CAediting_705747(122817703, -), CAediting_705748(122817706, -), CAediting_705749(122817711, -), CAediting_705750(122817712, -), CAediting_705751(122817720, -), CAediting_705752(122818002, -), CAediting_705753(122818009, -), CAediting_705754(122818011, -), CAediting_705755(122818023, -), CAediting_705756(122818025, -), CAediting_705757(122818047, -), CAediting_705758(122818065, -), CAediting_705759(122818074, -), CAediting_705760(122818076, -), CAediting_705761(122818102, -), CAediting_705762(122818120, -), CAediting_705763(122818138, -), CAediting_705764(122818146, -), CAediting_705765(122818156, -), CAediting_705766(122818168, -), CAediting_705767(122818182, -), CAediting_705768(122818205, -), CAediting_705769(122818211, -), CAediting_705770(122818266, -),

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RNA editing positional annotations for PDCL using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_705676	chr9_122816283_-	intronic
CAediting_705677	chr9_122816293_-	intronic
CAediting_705678	chr9_122816305_-	intronic
CAediting_705679	chr9_122816399_-	intronic
CAediting_705680	chr9_122816403_-	intronic
CAediting_705681	chr9_122816415_-	intronic
CAediting_705682	chr9_122816418_-	intronic
CAediting_705683	chr9_122816419_-	intronic
CAediting_705684	chr9_122816422_-	intronic
CAediting_705685	chr9_122816443_-	intronic
CAediting_705686	chr9_122816448_-	intronic
CAediting_705687	chr9_122816472_-	intronic
CAediting_705688	chr9_122817166_-	intronic
CAediting_705689	chr9_122817169_-	intronic
CAediting_705690	chr9_122817173_-	intronic
CAediting_705691	chr9_122817175_-	intronic
CAediting_705692	chr9_122817187_-	intronic
CAediting_705693	chr9_122817219_-	intronic
CAediting_705694	chr9_122817248_-	intronic
CAediting_705695	chr9_122817263_-	intronic
CAediting_705696	chr9_122817268_-	intronic
CAediting_705697	chr9_122817274_-	intronic
CAediting_705698	chr9_122817282_-	intronic
CAediting_705699	chr9_122817283_-	intronic
CAediting_705700	chr9_122817293_-	intronic
CAediting_705701	chr9_122817307_-	intronic
CAediting_705702	chr9_122817319_-	intronic
CAediting_705703	chr9_122817331_-	intronic
CAediting_705704	chr9_122817344_-	intronic
CAediting_705705	chr9_122817347_-	intronic
CAediting_705706	chr9_122817349_-	intronic
CAediting_705707	chr9_122817368_-	intronic
CAediting_705708	chr9_122817369_-	intronic
CAediting_705709	chr9_122817374_-	intronic
CAediting_705710	chr9_122817384_-	intronic
CAediting_705711	chr9_122817387_-	intronic
CAediting_705712	chr9_122817395_-	intronic
CAediting_705713	chr9_122817427_-	intronic
CAediting_705714	chr9_122817429_-	intronic
CAediting_705715	chr9_122817505_-	intronic
CAediting_705716	chr9_122817520_-	intronic
CAediting_705717	chr9_122817522_-	intronic
CAediting_705718	chr9_122817535_-	intronic
CAediting_705719	chr9_122817552_-	intronic
CAediting_705720	chr9_122817564_-	intronic
CAediting_705721	chr9_122817565_-	intronic
CAediting_705722	chr9_122817578_-	intronic
CAediting_705723	chr9_122817586_-	intronic
CAediting_705724	chr9_122817589_-	intronic
CAediting_705725	chr9_122817592_-	intronic
CAediting_705726	chr9_122817602_-	intronic
CAediting_705727	chr9_122817609_-	intronic
CAediting_705728	chr9_122817613_-	intronic
CAediting_705729	chr9_122817619_-	intronic
CAediting_705730	chr9_122817625_-	intronic
CAediting_705731	chr9_122817635_-	intronic
CAediting_705732	chr9_122817646_-	intronic
CAediting_705733	chr9_122817647_-	intronic
CAediting_705734	chr9_122817648_-	intronic
CAediting_705735	chr9_122817650_-	intronic
CAediting_705736	chr9_122817651_-	intronic
CAediting_705737	chr9_122817653_-	intronic
CAediting_705738	chr9_122817656_-	intronic
CAediting_705739	chr9_122817657_-	intronic
CAediting_705740	chr9_122817658_-	intronic
CAediting_705741	chr9_122817659_-	intronic
CAediting_705742	chr9_122817660_-	intronic
CAediting_705743	chr9_122817662_-	intronic
CAediting_705744	chr9_122817668_-	intronic
CAediting_705745	chr9_122817675_-	intronic
CAediting_705746	chr9_122817681_-	intronic
CAediting_705747	chr9_122817703_-	intronic
CAediting_705748	chr9_122817706_-	intronic
CAediting_705749	chr9_122817711_-	intronic
CAediting_705750	chr9_122817712_-	intronic
CAediting_705751	chr9_122817720_-	intronic
CAediting_705752	chr9_122818002_-	intronic
CAediting_705753	chr9_122818009_-	intronic
CAediting_705754	chr9_122818011_-	intronic
CAediting_705755	chr9_122818023_-	intronic
CAediting_705756	chr9_122818025_-	intronic
CAediting_705757	chr9_122818047_-	intronic
CAediting_705758	chr9_122818065_-	intronic
CAediting_705759	chr9_122818074_-	intronic
CAediting_705760	chr9_122818076_-	intronic
CAediting_705761	chr9_122818102_-	intronic
CAediting_705762	chr9_122818120_-	intronic
CAediting_705763	chr9_122818138_-	intronic
CAediting_705764	chr9_122818146_-	intronic
CAediting_705765	chr9_122818156_-	intronic
CAediting_705766	chr9_122818168_-	intronic
CAediting_705767	chr9_122818182_-	intronic
CAediting_705768	chr9_122818205_-	intronic
CAediting_705769	chr9_122818211_-	intronic
CAediting_705770	chr9_122818266_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_705676	chr9_122816283_-	DNA	hAT-Charlie	MER1A
CAediting_705677	chr9_122816293_-	DNA	hAT-Charlie	MER1A
CAediting_705678	chr9_122816305_-	DNA	hAT-Charlie	MER1A
CAediting_705679	chr9_122816399_-	DNA	hAT-Charlie	MER1A
CAediting_705680	chr9_122816403_-	DNA	hAT-Charlie	MER1A
CAediting_705681	chr9_122816415_-	DNA	hAT-Charlie	MER1A
CAediting_705682	chr9_122816418_-	DNA	hAT-Charlie	MER1A
CAediting_705683	chr9_122816419_-	DNA	hAT-Charlie	MER1A
CAediting_705684	chr9_122816422_-	DNA	hAT-Charlie	MER1A
CAediting_705685	chr9_122816443_-	DNA	hAT-Charlie	MER1A
CAediting_705686	chr9_122816448_-	DNA	hAT-Charlie	MER1A
CAediting_705687	chr9_122816472_-	DNA	hAT-Charlie	MER1A
CAediting_705688	chr9_122817166_-	SINE	Alu	AluSx1
CAediting_705689	chr9_122817169_-	SINE	Alu	AluSx1
CAediting_705690	chr9_122817173_-	SINE	Alu	AluSx1
CAediting_705691	chr9_122817175_-	SINE	Alu	AluSx1
CAediting_705692	chr9_122817187_-	SINE	Alu	AluSx1
CAediting_705693	chr9_122817219_-	SINE	Alu	AluSx1
CAediting_705694	chr9_122817248_-	SINE	Alu	AluSx1
CAediting_705695	chr9_122817263_-	SINE	Alu	AluSx1
CAediting_705696	chr9_122817268_-	SINE	Alu	AluSx1
CAediting_705697	chr9_122817274_-	SINE	Alu	AluSx1
CAediting_705698	chr9_122817282_-	SINE	Alu	AluSx1
CAediting_705699	chr9_122817283_-	SINE	Alu	AluSx1
CAediting_705700	chr9_122817293_-	SINE	Alu	AluSx1
CAediting_705701	chr9_122817307_-	SINE	Alu	AluSx1
CAediting_705702	chr9_122817319_-	SINE	Alu	AluSx1
CAediting_705703	chr9_122817331_-	SINE	Alu	AluSx1
CAediting_705704	chr9_122817344_-	SINE	Alu	AluSx1
CAediting_705705	chr9_122817347_-	SINE	Alu	AluSx1
CAediting_705706	chr9_122817349_-	SINE	Alu	AluSx1
CAediting_705707	chr9_122817368_-	SINE	Alu	AluSx1
CAediting_705708	chr9_122817369_-	SINE	Alu	AluSx1
CAediting_705709	chr9_122817374_-	SINE	Alu	AluSx1
CAediting_705710	chr9_122817384_-	SINE	Alu	AluSx1
CAediting_705711	chr9_122817387_-	SINE	Alu	AluSx1
CAediting_705712	chr9_122817395_-	SINE	Alu	AluSx1
CAediting_705713	chr9_122817427_-	SINE	Alu	AluSx1
CAediting_705714	chr9_122817429_-	SINE	Alu	AluSx1
CAediting_705715	chr9_122817505_-	SINE	Alu	AluJb
CAediting_705716	chr9_122817520_-	SINE	Alu	AluJb
CAediting_705717	chr9_122817522_-	SINE	Alu	AluJb
CAediting_705718	chr9_122817535_-	SINE	Alu	AluJb
CAediting_705719	chr9_122817552_-	SINE	Alu	AluJb
CAediting_705720	chr9_122817564_-	SINE	Alu	AluJb
CAediting_705721	chr9_122817565_-	SINE	Alu	AluJb
CAediting_705722	chr9_122817578_-	SINE	Alu	AluJb
CAediting_705723	chr9_122817586_-	SINE	Alu	AluJb
CAediting_705724	chr9_122817589_-	SINE	Alu	AluJb
CAediting_705725	chr9_122817592_-	SINE	Alu	AluJb
CAediting_705726	chr9_122817602_-	SINE	Alu	AluJb
CAediting_705727	chr9_122817609_-	SINE	Alu	AluJb
CAediting_705728	chr9_122817613_-	SINE	Alu	AluJb
CAediting_705729	chr9_122817619_-	SINE	Alu	AluJb
CAediting_705730	chr9_122817625_-	SINE	Alu	AluJb
CAediting_705731	chr9_122817635_-	SINE	Alu	AluJb
CAediting_705732	chr9_122817646_-	SINE	Alu	AluJb
CAediting_705733	chr9_122817647_-	SINE	Alu	AluJb
CAediting_705734	chr9_122817648_-	SINE	Alu	AluJb
CAediting_705735	chr9_122817650_-	SINE	Alu	AluJb
CAediting_705736	chr9_122817651_-	SINE	Alu	AluJb
CAediting_705737	chr9_122817653_-	SINE	Alu	AluJb
CAediting_705738	chr9_122817656_-	SINE	Alu	AluJb
CAediting_705739	chr9_122817657_-	SINE	Alu	AluJb
CAediting_705740	chr9_122817658_-	SINE	Alu	AluJb
CAediting_705741	chr9_122817659_-	SINE	Alu	AluJb
CAediting_705742	chr9_122817660_-	SINE	Alu	AluJb
CAediting_705743	chr9_122817662_-	SINE	Alu	AluJb
CAediting_705744	chr9_122817668_-	SINE	Alu	AluJb
CAediting_705745	chr9_122817675_-	SINE	Alu	AluJb
CAediting_705746	chr9_122817681_-	SINE	Alu	AluJb
CAediting_705747	chr9_122817703_-	SINE	Alu	AluJb
CAediting_705748	chr9_122817706_-	SINE	Alu	AluJb
CAediting_705749	chr9_122817711_-	SINE	Alu	AluJb
CAediting_705750	chr9_122817712_-	SINE	Alu	AluJb
CAediting_705751	chr9_122817720_-	SINE	Alu	AluJb
CAediting_705752	chr9_122818002_-	SINE	Alu	AluSx
CAediting_705753	chr9_122818009_-	SINE	Alu	AluSx
CAediting_705754	chr9_122818011_-	SINE	Alu	AluSx
CAediting_705755	chr9_122818023_-	SINE	Alu	AluSx
CAediting_705756	chr9_122818025_-	SINE	Alu	AluSx
CAediting_705757	chr9_122818047_-	SINE	Alu	AluSx
CAediting_705758	chr9_122818065_-	SINE	Alu	AluSx
CAediting_705759	chr9_122818074_-	SINE	Alu	AluSx
CAediting_705760	chr9_122818076_-	SINE	Alu	AluSx
CAediting_705761	chr9_122818102_-	SINE	Alu	AluSx
CAediting_705762	chr9_122818120_-	SINE	Alu	AluSx
CAediting_705763	chr9_122818138_-	SINE	Alu	AluSx
CAediting_705764	chr9_122818146_-	SINE	Alu	AluSx
CAediting_705765	chr9_122818156_-	SINE	Alu	AluSx
CAediting_705766	chr9_122818168_-	SINE	Alu	AluSx
CAediting_705767	chr9_122818182_-	SINE	Alu	AluSx
CAediting_705768	chr9_122818205_-	SINE	Alu	AluSx
CAediting_705769	chr9_122818211_-	SINE	Alu	AluSx
CAediting_705770	chr9_122818266_-	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for PDCL

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000136940.12.PDCL.

Correlation between RNA A-to-I editing and PSI for ENSG00000136940.12.PDCL.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PDCL

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ESCA.CAediting_705691.ENSG00000136940.PDCL.png
Soverview

LUSC.CAediting_705722.ENSG00000136940.PDCL.png
Soverview

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Protein coding region RNA A-to-I editings for PDCL

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for PDCL

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229414	chr17_67471546_+	ENSG00000136940.12	ENST00000394285	hsa-miR-548aa	122820782	122820788	7mer-m8	122820781	122820805	140	-14.06
CAediting_396018	chr5_1062918_-	ENSG00000136940.12	ENST00000394285	hsa-miR-4635	122820765	122820771	7mer-m8	122820764	122820784	162	-21.35

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PDCL

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for PDCL

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_705676	chr9_122816283_-	8.47788996281283e-05	0.464667519122848	.	.	.	.
BRCA	CAediting_705678	chr9_122816305_-	0.000461147025488297	0.2503588287146	.	.	.	.
LIHC	CAediting_705678	chr9_122816305_-	.	.	.	.	0.00101420167200148	0.450944684792444
LUAD	CAediting_705678	chr9_122816305_-	5.61837390136958e-06	0.444790831260675	.	.	.	.
LUSC	CAediting_705678	chr9_122816305_-	0.0195784434513363	0.322840284044988	.	.	.	.
THCA	CAediting_705678	chr9_122816305_-	0.00674719735977057	0.312320720716068	.	.	.	.
UCEC	CAediting_705678	chr9_122816305_-	.	.	0.000552297004092527	0.44335553391306	0.0156172196633552	0.318892826697423
PCPG	CAediting_705678	chr9_122816305_-	0.0334936039470399	0.289866846376557	.	.	.	.
BLCA	CAediting_705684	chr9_122816422_-	0.000413923311368806	0.349837303823224	.	.	.	.
LGG	CAediting_705684	chr9_122816422_-	0.000470217945175718	0.46372385029559	.	.	.	.
BRCA	CAediting_705684	chr9_122816422_-	2.84081005787208e-06	0.263970514041752	.	.	.	.
LUAD	CAediting_705684	chr9_122816422_-	9.37889530832984e-07	0.425355797670582	.	.	.	.
PRAD	CAediting_705684	chr9_122816422_-	0.0267140555920749	0.264843691845793	.	.	.	.
SARC	CAediting_705684	chr9_122816422_-	0.0130463875595287	0.297492765793479	.	.	.	.
BLCA	CAediting_705691	chr9_122817175_-	0.00359773806438576	0.307210005436626	.	.	.	.
LGG	CAediting_705691	chr9_122817175_-	0.000818788002554821	0.218224397068955	.	.	.	.
BRCA	CAediting_705691	chr9_122817175_-	6.02536631654061e-21	0.42676860549601	.	.	.	.
CESC	CAediting_705691	chr9_122817175_-	0.00826637009070361	0.289810357856738	.	.	.	.
LUAD	CAediting_705691	chr9_122817175_-	0.00262944381027071	0.262730840769276	.	.	.	.
COAD	CAediting_705691	chr9_122817175_-	0.0224600601161996	0.313063274409592	.	.	.	.
LUSC	CAediting_705691	chr9_122817175_-	1.14178084695997e-05	0.331429016975325	.	.	.	.
GBM	CAediting_705691	chr9_122817175_-	0.00012640275474734	0.319464143966916	.	.	.	.
PRAD	CAediting_705691	chr9_122817175_-	7.25367266682086e-06	0.278376212097177	.	.	.	.
HNSC	CAediting_705691	chr9_122817175_-	1.95450376309057e-05	0.348855553453827	0.00389638484848697	0.239944869014865	.	.
STAD	CAediting_705691	chr9_122817175_-	0.0287248157331413	0.160850911137261	.	.	.	.
UCEC	CAediting_705691	chr9_122817175_-	0.0127726832317944	0.275575233131586	.	.	.	.
OV	CAediting_705691	chr9_122817175_-	8.73755436403132e-05	0.286656273738839	.	.	.	.
PCPG	CAediting_705691	chr9_122817175_-	1.48087207386346e-05	0.463666090353287	.	.	.	.
SKCM	CAediting_705691	chr9_122817175_-	1.52213395925589e-06	0.425906547250399	.	.	.	.
SARC	CAediting_705691	chr9_122817175_-	2.97804151649332e-05	0.500284636067541	.	.	.	.
TGCT	CAediting_705691	chr9_122817175_-	0.000429057863069594	0.447441591902828	.	.	.	.
BRCA	CAediting_705692	chr9_122817187_-	1.73239244157418e-07	0.309349053766783	.	.	.	.
LUAD	CAediting_705692	chr9_122817187_-	5.0137248023938e-05	0.464934393620643	.	.	.	.
STAD	CAediting_705696	chr9_122817268_-	0.00388095101007565	0.27693361634231	.	.	.	.
ESCA	CAediting_705696	chr9_122817268_-	0.00228595545722905	0.298778733237824	.	.	.	.
OV	CAediting_705696	chr9_122817268_-	0.0181740008954251	0.231264335028458	.	.	.	.
STAD	CAediting_705700	chr9_122817293_-	0.0281620770048887	0.25526838941332	.	.	.	.
ESCA	CAediting_705700	chr9_122817293_-	.	.	0.0082356863404437	0.332718235013944	.	.
BRCA	CAediting_705709	chr9_122817374_-	0.0389875774445484	0.245583030391285	.	.	.	.
LGG	CAediting_705714	chr9_122817429_-	0.0225440247518631	0.241614760802974	.	.	.	.
ESCA	CAediting_705714	chr9_122817429_-	.	.	0.000575151839452322	0.404054182286237	.	.
LGG	CAediting_705722	chr9_122817578_-	.	.	.	.	0.0258817709800096	0.117590208920555
BRCA	CAediting_705722	chr9_122817578_-	2.20276005054752e-08	0.212046254961284	.	.	.	.
LUSC	CAediting_705722	chr9_122817578_-	0.0397972024239728	0.13393189287441	.	.	.	.
PRAD	CAediting_705722	chr9_122817578_-	5.22479211952037e-05	0.210950379676281	.	.	.	.
UCEC	CAediting_705722	chr9_122817578_-	.	.	.	.	0.0134245973289185	0.248988422926058
PAAD	CAediting_705722	chr9_122817578_-	0.00714334107046272	0.312323527647955	.	.	.	.
PCPG	CAediting_705722	chr9_122817578_-	0.0317700548466794	0.20489942706295	.	.	.	.
SKCM	CAediting_705722	chr9_122817578_-	0.00320381801453986	0.194403993211596	.	.	.	.
SARC	CAediting_705722	chr9_122817578_-	0.00142245061085952	0.278016223270516	.	.	.	.
TGCT	CAediting_705722	chr9_122817578_-	0.026596895241823	0.313561132460055	.	.	.	.
STAD	CAediting_705732	chr9_122817646_-	0.0182732449919429	0.245626775474451	.	.	.	.
STAD	CAediting_705733	chr9_122817647_-	.	.	0.023982994376547	0.178987618430676	.	.
ESCA	CAediting_705733	chr9_122817647_-	.	.	4.58157524816544e-06	0.44641070953215	.	.
OV	CAediting_705733	chr9_122817647_-	.	.	0.0246054546961577	0.215227203543378	.	.
BRCA	CAediting_705734	chr9_122817648_-	0.00766028789818734	0.24643378863303	.	.	.	.
OV	CAediting_705734	chr9_122817648_-	0.0417074801538838	0.208285022081439	.	.	.	.
STAD	CAediting_705739	chr9_122817657_-	0.0366859427907595	0.15761989930457	.	.	.	.
LGG	CAediting_705749	chr9_122817711_-	0.0228754243424876	0.228563775902273	.	.	.	.
BRCA	CAediting_705749	chr9_122817711_-	0.000336938174340946	0.18131506895966	.	.	.	.
LUAD	CAediting_705749	chr9_122817711_-	0.00156875811559361	0.270547742416552	.	.	.	.
STAD	CAediting_705749	chr9_122817711_-	0.00748709278683168	0.227565599968592	.	.	.	.
ESCA	CAediting_705749	chr9_122817711_-	0.0150439983770969	0.236723249905218	.	.	.	.
PCPG	CAediting_705749	chr9_122817711_-	0.000820685394326938	0.404915417982334	.	.	.	.
SKCM	CAediting_705749	chr9_122817711_-	0.0288150567493777	0.24607214195157	.	.	.	.
BLCA	CAediting_705750	chr9_122817712_-	0.000419255802610945	0.289174280787867	.	.	0.0480747959099826	0.164460444722453
LGG	CAediting_705750	chr9_122817712_-	0.000602530375937937	0.224047784619346	.	.	.	.
BRCA	CAediting_705750	chr9_122817712_-	1.87899579371179e-21	0.369439470452959	.	.	.	.
LUAD	CAediting_705750	chr9_122817712_-	2.86099032860059e-09	0.373710900172619	.	.	.	.
COAD	CAediting_705750	chr9_122817712_-	0.00383778913153432	0.341269691165138	.	.	.	.
LUSC	CAediting_705750	chr9_122817712_-	0.0063447467145626	0.22047353799905	.	.	.	.
PRAD	CAediting_705750	chr9_122817712_-	9.26180617309252e-07	0.280632503485417	0.0429142191188332	0.11776274542222	.	.
HNSC	CAediting_705750	chr9_122817712_-	0.000682467719900446	0.241180414298753	.	.	.	.
STAD	CAediting_705750	chr9_122817712_-	0.00166327627871469	0.209879326893905	.	.	.	.
THCA	CAediting_705750	chr9_122817712_-	0.0464906448645701	0.149438934076137	.	.	.	.
ESCA	CAediting_705750	chr9_122817712_-	0.00749660619992344	0.21897889756419	.	.	.	.
OV	CAediting_705750	chr9_122817712_-	0.000342947280672858	0.291367378931982	.	.	.	.
PAAD	CAediting_705750	chr9_122817712_-	0.0180488336327933	0.286035506938946	.	.	.	.
PCPG	CAediting_705750	chr9_122817712_-	0.000162498699164669	0.356692229382876	.	.	.	.
SKCM	CAediting_705750	chr9_122817712_-	5.49422013460871e-08	0.428599526607015	.	.	.	.
SARC	CAediting_705750	chr9_122817712_-	0.000375277344515474	0.395176842812222	.	.	.	.
TGCT	CAediting_705750	chr9_122817712_-	0.0171143754109855	0.3147027641833	.	.	.	.
BRCA	CAediting_705751	chr9_122817720_-	0.0258276289346361	0.109540618845603	.	.	.	.
LUAD	CAediting_705751	chr9_122817720_-	0.00733246775526151	0.21668515844199	.	.	.	.
PRAD	CAediting_705751	chr9_122817720_-	0.00909348835056698	0.189279209579529	.	.	.	.
ESCA	CAediting_705751	chr9_122817720_-	0.0390830158359633	0.190230159526762	.	.	.	.
PCPG	CAediting_705751	chr9_122817720_-	0.0137345992106638	0.289226778092185	.	.	.	.

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Relation with cancer stages for PDCL

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_705722	chr9_122817578_-	0.00433597641986073	0.221003904743532
BLCA	pathologic_stage	CAediting_705751	chr9_122817720_-	0.0153507491296673	0.246791393951707
BRCA	pathologic_stage	CAediting_705692	chr9_122817187_-	0.000764166147732388	0.204359501591363
BRCA	pathologic_stage	CAediting_705750	chr9_122817712_-	0.033722861137707	0.086487688756414
BRCA	pathologic_stage	CAediting_705751	chr9_122817720_-	0.0470251629508874	0.098752668444008
CESC	clinical_stage	CAediting_705722	chr9_122817578_-	0.0189819055297141	-0.188261929048965
ESCA	clinical_stage	CAediting_705750	chr9_122817712_-	0.0134303132447977	-0.347435411487916
HNSC	pathologic_stage	CAediting_705722	chr9_122817578_-	0.00369162994044005	0.189904080689806
HNSC	pathologic_stage	CAediting_705750	chr9_122817712_-	0.0456295909757715	0.156315167547021
KIRC	pathologic_stage	CAediting_705692	chr9_122817187_-	0.0173625493212884	0.199389572875279
KIRC	pathologic_stage	CAediting_705714	chr9_122817429_-	0.00279857749505679	0.349669183720268
KIRC	pathologic_stage	CAediting_705733	chr9_122817647_-	0.00440419502101986	0.323190209577246
KIRC	pathologic_stage	CAediting_705734	chr9_122817648_-	0.0481065895777559	0.260685870435793
KIRC	pathologic_stage	CAediting_705749	chr9_122817711_-	0.00367584994242733	0.211987234846093
KIRC	pathologic_stage	CAediting_705750	chr9_122817712_-	0.0088641584907425	0.143222786841119
KIRC	pathologic_stage	CAediting_705751	chr9_122817720_-	0.0285253437577305	0.14635452349205
LIHC	pathologic_stage	CAediting_705678	chr9_122816305_-	0.048238300928008	-0.289710897923035
LUAD	pathologic_stage	CAediting_705722	chr9_122817578_-	0.0351104361524485	0.129503685452705
THCA	pathologic_stage	CAediting_705750	chr9_122817712_-	0.018319008350023	0.177673154603095

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Relation with survival for PDCL

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
BLCA	CAediting_705722	chr9_122817578_-	0.0225681618774493	0.0379311	5.04591
LGG	CAediting_705684	chr9_122816422_-	0.00743988834815712	0.019672	8285670
BRCA	CAediting_705730	chr9_122817625_-	0.00822659004484139	0.0468611	55632200000
OV	CAediting_705696	chr9_122817268_-	0.0082102275288426	0.0250565	6.83883
OV	CAediting_705714	chr9_122817429_-	0.0330136853201924	0.0377363	0.0707924
SARC	CAediting_705691	chr9_122817175_-	0.00872963608362998	0.00794815	96.6876

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RelatedDrugs for PDCL

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for PDCL

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene