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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: NPM1 (CAeditome ID:4869)

Gene summary for NPM1

check button Gene summary
Gene informationGene symbol

NPM1

Gene ID

4869

Gene namenucleophosmin 1
SynonymsB23|NPM
Cytomap

5q35.1

Type of geneprotein-coding
Descriptionnucleophosminnucleolar protein NO38nucleophosmin (nucleolar phosphoprotein B23, numatrin)nucleophosmin/nucleoplasmin family, member 1testicular tissue protein Li 128
Modification date20210524
UniProtAcc

P06748

Context- 33959979(The potential role of nucleophosmin (NPM1) in the development of cancer)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
NPM1

GO:0001046

Nucleophosmin

19160485

NPM1

GO:0003713

Nucleophosmin

15087454

NPM1

GO:0003713

Nucleophosmin

19160485

NPM1

GO:0003723

Nucleophosmin

12058066

NPM1

GO:0004860

Nucleophosmin

12882984

NPM1

GO:0030957

Nucleophosmin

9094689

NPM1

GO:0042393

Nucleophosmin

11602260

NPM1

GO:0042803

Nucleophosmin

9121481

NPM1

GO:0043023

Nucleophosmin

18809582

NPM1

GO:0043024

Nucleophosmin

18809582

NPM1

GO:0051059

Nucleophosmin

15087454

NPM1

GO:0051082

Nucleophosmin

10211837

NPM1

GO:0006281

Nucleophosmin

19188445

NPM1

GO:0006334

Nucleophosmin

11602260

NPM1

GO:0006913

Nucleophosmin

16041368

NPM1

GO:0008104

Nucleophosmin

18420587

NPM1

GO:0008284

Nucleophosmin

22528486

NPM1

GO:0032071

Nucleophosmin

19188445

NPM1

GO:0034644

Nucleophosmin

19160485

NPM1

GO:0043066

Nucleophosmin

12882984

NPM1

GO:0044387

Nucleophosmin

12882984

NPM1

GO:0045727

Nucleophosmin

12882984

NPM1

GO:0045893

Nucleophosmin

22528486

NPM1

GO:0045944

Nucleophosmin

19160485

NPM1

GO:0060699

Nucleophosmin

19188445

NPM1

GO:0060735

Nucleophosmin

12882984

NPM1

GO:1902751

Nucleophosmin

22528486

NPM1

GO:0005634

Nucleophosmin

12080348

NPM1

GO:0005634

Nucleophosmin

22720776

NPM1

GO:0005654

Nucleophosmin

0000052

NPM1

GO:0005654

Nucleophosmin

12058066

NPM1

GO:0005654

Nucleophosmin

19160485

NPM1

GO:0005730

Nucleophosmin

0000052

NPM1

GO:0005730

Nucleophosmin

11420665

NPM1

GO:0005730

Nucleophosmin

12080348

NPM1

GO:0005730

Nucleophosmin

16041368

NPM1

GO:0005730

Nucleophosmin

17475909

NPM1

GO:0005730

Nucleophosmin

18809582

NPM1

GO:0005730

Nucleophosmin

19160485

NPM1

GO:0005730

Nucleophosmin

19188445

NPM1

GO:0005730

Nucleophosmin

19208757

NPM1

GO:0005730

Nucleophosmin

22528486

NPM1

GO:0005730

Nucleophosmin

25956029

NPM1

GO:0005737

Nucleophosmin

9121481

NPM1

GO:0005813

Nucleophosmin

11051553

NPM1

GO:0031616

Nucleophosmin

16041368

NPM1

GO:0032991

Nucleophosmin

19160485

NPM1

GO:0032993

Nucleophosmin

19160485

NPM1

GO:1990904

Nucleophosmin

18809582


Top

RNA A-to-I events for NPM1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000181163.12
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_446505(171392401, +), CAediting_446506(171393932, +), CAediting_446507(171394354, +), CAediting_446508(171394357, +), CAediting_446509(171394402, +), CAediting_446510(171394978, +), CAediting_446511(171395018, +), CAediting_446512(171395073, +), CAediting_446513(171395089, +), CAediting_446514(171395121, +), CAediting_446515(171395124, +), CAediting_446516(171395129, +), CAediting_446517(171395130, +), CAediting_446518(171395176, +), CAediting_446519(171395380, +), CAediting_446520(171395393, +), CAediting_446521(171395400, +), CAediting_446522(171395429, +), CAediting_446523(171395439, +), CAediting_446524(171395480, +), CAediting_446525(171395483, +), CAediting_446526(171395510, +), CAediting_446527(171395543, +), CAediting_446528(171396195, +), CAediting_446529(171396717, +), CAediting_446530(171396719, +), CAediting_446531(171396726, +), CAediting_446532(171396858, +), CAediting_446533(171396879, +), CAediting_446534(171396893, +), CAediting_446535(171396953, +), CAediting_446536(171397680, +), CAediting_446537(171398513, +), CAediting_446538(171398519, +), CAediting_446539(171398520, +), CAediting_446540(171398584, +), CAediting_446541(171398585, +), CAediting_446542(171398612, +), CAediting_446543(171398613, +), CAediting_446544(171398615, +), CAediting_446545(171398618, +), CAediting_446546(171398624, +), CAediting_446547(171398632, +), CAediting_446548(171398637, +), CAediting_446549(171398650, +), CAediting_446550(171398660, +), CAediting_446551(171398704, +), CAediting_446552(171398706, +), CAediting_446553(171398903, +), CAediting_446554(171398913, +), CAediting_446555(171398980, +), CAediting_446556(171398990, +), CAediting_446557(171398992, +), CAediting_446558(171399016, +), CAediting_446559(171399071, +), CAediting_446560(171399277, +), CAediting_446561(171399348, +), CAediting_446562(171399372, +), CAediting_446563(171399379, +), CAediting_446564(171399499, +), CAediting_446565(171399505, +), CAediting_446566(171400604, +), CAediting_446567(171401138, +), CAediting_446568(171401143, +), CAediting_446569(171401148, +), CAediting_446570(171401151, +), CAediting_446571(171401181, +), CAediting_446572(171401182, +), CAediting_446573(171401202, +), CAediting_446574(171401205, +), CAediting_446575(171401206, +), CAediting_446576(171401207, +), CAediting_446577(171401208, +), CAediting_446578(171401237, +), CAediting_446579(171401238, +), CAediting_446580(171401251, +), CAediting_446581(171401269, +), CAediting_446582(171401468, +), CAediting_446583(171401490, +), CAediting_446584(171401492, +), CAediting_446585(171401562, +), CAediting_446586(171401563, +), CAediting_446587(171401566, +), CAediting_446588(171401576, +), CAediting_446589(171401598, +), CAediting_446590(171401621, +), CAediting_446591(171401651, +), CAediting_446592(171401662, +), CAediting_446593(171401663, +), CAediting_446594(171401664, +), CAediting_446595(171401671, +), CAediting_446596(171401681, +), CAediting_446597(171404991, +), CAediting_446598(171404999, +), CAediting_446599(171405007, +), CAediting_446600(171405055, +), CAediting_446601(171405077, +), CAediting_446602(171405099, +), CAediting_446603(171405130, +), CAediting_446604(171409331, +), CAediting_446605(171409336, +), CAediting_446606(171409374, +), CAediting_446607(171409387, +), CAediting_446608(171409390, +), CAediting_446609(171409391, +), CAediting_446610(171409392, +), CAediting_446611(171409393, +), CAediting_446612(171409394, +), CAediting_446613(171409396, +), CAediting_446614(171409399, +), CAediting_446615(171409405, +), CAediting_446616(171409441, +), CAediting_446617(171409445, +), CAediting_446618(171409458, +), CAediting_446619(171409473, +), CAediting_446620(171409531, +), CAediting_446621(171409752, +), CAediting_446622(171409869, +), CAediting_446623(171409894, +), CAediting_446624(171409898, +), CAediting_446625(171409907, +), CAediting_446626(171409947, +), CAediting_446627(171409954, +), CAediting_446628(171409963, +), CAediting_446629(171409964, +), CAediting_446630(171409972, +), CAediting_446631(171409978, +), CAediting_446632(171409981, +), CAediting_446633(171409983, +), CAediting_446634(171409985, +), CAediting_446635(171409993, +), CAediting_446636(171410031, +), CAediting_446637(171410070, +), CAediting_446638(171410072, +), CAediting_446639(171410079, +),

Top

RNA editing positional annotations for NPM1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_446505chr5_171392401_+ncRNA_intronic
CAediting_446506chr5_171393932_+intronic
CAediting_446507chr5_171394354_+intronic
CAediting_446508chr5_171394357_+intronic
CAediting_446509chr5_171394402_+intronic
CAediting_446510chr5_171394978_+intronic
CAediting_446511chr5_171395018_+intronic
CAediting_446512chr5_171395073_+intronic
CAediting_446513chr5_171395089_+intronic
CAediting_446514chr5_171395121_+intronic
CAediting_446515chr5_171395124_+intronic
CAediting_446516chr5_171395129_+intronic
CAediting_446517chr5_171395130_+intronic
CAediting_446518chr5_171395176_+intronic
CAediting_446519chr5_171395380_+intronic
CAediting_446520chr5_171395393_+intronic
CAediting_446521chr5_171395400_+intronic
CAediting_446522chr5_171395429_+intronic
CAediting_446523chr5_171395439_+intronic
CAediting_446524chr5_171395480_+intronic
CAediting_446525chr5_171395483_+intronic
CAediting_446526chr5_171395510_+intronic
CAediting_446527chr5_171395543_+intronic
CAediting_446528chr5_171396195_+intronic
CAediting_446529chr5_171396717_+intronic
CAediting_446530chr5_171396719_+intronic
CAediting_446531chr5_171396726_+intronic
CAediting_446532chr5_171396858_+intronic
CAediting_446533chr5_171396879_+intronic
CAediting_446534chr5_171396893_+intronic
CAediting_446535chr5_171396953_+intronic
CAediting_446536chr5_171397680_+intronic
CAediting_446537chr5_171398513_+intronic
CAediting_446538chr5_171398519_+intronic
CAediting_446539chr5_171398520_+intronic
CAediting_446540chr5_171398584_+intronic
CAediting_446541chr5_171398585_+intronic
CAediting_446542chr5_171398612_+intronic
CAediting_446543chr5_171398613_+intronic
CAediting_446544chr5_171398615_+intronic
CAediting_446545chr5_171398618_+intronic
CAediting_446546chr5_171398624_+intronic
CAediting_446547chr5_171398632_+intronic
CAediting_446548chr5_171398637_+intronic
CAediting_446549chr5_171398650_+intronic
CAediting_446550chr5_171398660_+intronic
CAediting_446551chr5_171398704_+intronic
CAediting_446552chr5_171398706_+intronic
CAediting_446553chr5_171398903_+intronic
CAediting_446554chr5_171398913_+intronic
CAediting_446555chr5_171398980_+intronic
CAediting_446556chr5_171398990_+intronic
CAediting_446557chr5_171398992_+intronic
CAediting_446558chr5_171399016_+intronic
CAediting_446559chr5_171399071_+intronic
CAediting_446560chr5_171399277_+intronic
CAediting_446561chr5_171399348_+intronic
CAediting_446562chr5_171399372_+intronic
CAediting_446563chr5_171399379_+intronic
CAediting_446564chr5_171399499_+intronic
CAediting_446565chr5_171399505_+intronic
CAediting_446566chr5_171400604_+intronic
CAediting_446567chr5_171401138_+ncRNA_intronic
CAediting_446568chr5_171401143_+ncRNA_intronic
CAediting_446569chr5_171401148_+ncRNA_intronic
CAediting_446570chr5_171401151_+ncRNA_intronic
CAediting_446571chr5_171401181_+ncRNA_intronic
CAediting_446572chr5_171401182_+ncRNA_intronic
CAediting_446573chr5_171401202_+ncRNA_intronic
CAediting_446574chr5_171401205_+ncRNA_intronic
CAediting_446575chr5_171401206_+ncRNA_intronic
CAediting_446576chr5_171401207_+ncRNA_intronic
CAediting_446577chr5_171401208_+ncRNA_intronic
CAediting_446578chr5_171401237_+ncRNA_intronic
CAediting_446579chr5_171401238_+ncRNA_intronic
CAediting_446580chr5_171401251_+ncRNA_intronic
CAediting_446581chr5_171401269_+ncRNA_intronic
CAediting_446582chr5_171401468_+ncRNA_intronic
CAediting_446583chr5_171401490_+ncRNA_intronic
CAediting_446584chr5_171401492_+ncRNA_intronic
CAediting_446585chr5_171401562_+ncRNA_intronic
CAediting_446586chr5_171401563_+ncRNA_intronic
CAediting_446587chr5_171401566_+ncRNA_intronic
CAediting_446588chr5_171401576_+ncRNA_intronic
CAediting_446589chr5_171401598_+ncRNA_intronic
CAediting_446590chr5_171401621_+ncRNA_intronic
CAediting_446591chr5_171401651_+ncRNA_intronic
CAediting_446592chr5_171401662_+ncRNA_intronic
CAediting_446593chr5_171401663_+ncRNA_intronic
CAediting_446594chr5_171401664_+ncRNA_intronic
CAediting_446595chr5_171401671_+ncRNA_intronic
CAediting_446596chr5_171401681_+ncRNA_intronic
CAediting_446597chr5_171404991_+ncRNA_intronic
CAediting_446598chr5_171404999_+ncRNA_intronic
CAediting_446599chr5_171405007_+ncRNA_intronic
CAediting_446600chr5_171405055_+ncRNA_intronic
CAediting_446601chr5_171405077_+ncRNA_intronic
CAediting_446602chr5_171405099_+ncRNA_intronic
CAediting_446603chr5_171405130_+ncRNA_intronic
CAediting_446604chr5_171409331_+ncRNA_intronic
CAediting_446605chr5_171409336_+ncRNA_intronic
CAediting_446606chr5_171409374_+ncRNA_intronic
CAediting_446607chr5_171409387_+ncRNA_intronic
CAediting_446608chr5_171409390_+ncRNA_intronic
CAediting_446609chr5_171409391_+ncRNA_intronic
CAediting_446610chr5_171409392_+ncRNA_intronic
CAediting_446611chr5_171409393_+ncRNA_intronic
CAediting_446612chr5_171409394_+ncRNA_intronic
CAediting_446613chr5_171409396_+ncRNA_intronic
CAediting_446614chr5_171409399_+ncRNA_intronic
CAediting_446615chr5_171409405_+ncRNA_intronic
CAediting_446616chr5_171409441_+ncRNA_intronic
CAediting_446617chr5_171409445_+ncRNA_intronic
CAediting_446618chr5_171409458_+ncRNA_intronic
CAediting_446619chr5_171409473_+ncRNA_intronic
CAediting_446620chr5_171409531_+ncRNA_intronic
CAediting_446621chr5_171409752_+ncRNA_intronic
CAediting_446622chr5_171409869_+ncRNA_intronic
CAediting_446623chr5_171409894_+ncRNA_intronic
CAediting_446624chr5_171409898_+ncRNA_intronic
CAediting_446625chr5_171409907_+ncRNA_intronic
CAediting_446626chr5_171409947_+ncRNA_intronic
CAediting_446627chr5_171409954_+ncRNA_intronic
CAediting_446628chr5_171409963_+ncRNA_intronic
CAediting_446629chr5_171409964_+ncRNA_intronic
CAediting_446630chr5_171409972_+ncRNA_intronic
CAediting_446631chr5_171409978_+ncRNA_intronic
CAediting_446632chr5_171409981_+ncRNA_intronic
CAediting_446633chr5_171409983_+ncRNA_intronic
CAediting_446634chr5_171409985_+ncRNA_intronic
CAediting_446635chr5_171409993_+ncRNA_intronic
CAediting_446636chr5_171410031_+ncRNA_intronic
CAediting_446637chr5_171410070_+ncRNA_intronic
CAediting_446638chr5_171410072_+ncRNA_intronic
CAediting_446639chr5_171410079_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_446505chr5_171392401_+SINEAluAluJr4
CAediting_446507chr5_171394354_+SINEAluAluSx
CAediting_446508chr5_171394357_+SINEAluAluSx
CAediting_446509chr5_171394402_+SINEAluAluSx
CAediting_446510chr5_171394978_+SINEAluAluSz
CAediting_446511chr5_171395018_+SINEAluAluSz
CAediting_446512chr5_171395073_+SINEAluAluSz
CAediting_446513chr5_171395089_+SINEAluAluSz
CAediting_446514chr5_171395121_+SINEAluAluSz
CAediting_446515chr5_171395124_+SINEAluAluSz
CAediting_446516chr5_171395129_+SINEAluAluSz
CAediting_446517chr5_171395130_+SINEAluAluSz
CAediting_446518chr5_171395176_+SINEAluAluSz
CAediting_446519chr5_171395380_+SINEAluAluSq10
CAediting_446520chr5_171395393_+SINEAluAluSq10
CAediting_446521chr5_171395400_+SINEAluAluSq10
CAediting_446522chr5_171395429_+SINEAluAluSq10
CAediting_446523chr5_171395439_+SINEAluAluSq10
CAediting_446524chr5_171395480_+SINEAluAluSq10
CAediting_446525chr5_171395483_+SINEAluAluSq10
CAediting_446526chr5_171395510_+SINEAluAluSq10
CAediting_446527chr5_171395543_+SINEAluAluSq10
CAediting_446528chr5_171396195_+SINEAluAluSx
CAediting_446529chr5_171396717_+SINEAluAluSq2
CAediting_446530chr5_171396719_+SINEAluAluSq2
CAediting_446531chr5_171396726_+SINEAluAluSq2
CAediting_446532chr5_171396858_+SINEAluAluSq2
CAediting_446533chr5_171396879_+SINEAluAluSq2
CAediting_446534chr5_171396893_+SINEAluAluSq2
CAediting_446535chr5_171396953_+SINEAluAluSq2
CAediting_446536chr5_171397680_+SINEAluAluSz6
CAediting_446537chr5_171398513_+SINEAluAluSc
CAediting_446538chr5_171398519_+SINEAluAluSc
CAediting_446539chr5_171398520_+SINEAluAluSc
CAediting_446540chr5_171398584_+SINEAluAluSc
CAediting_446541chr5_171398585_+SINEAluAluSc
CAediting_446542chr5_171398612_+SINEAluAluSc
CAediting_446543chr5_171398613_+SINEAluAluSc
CAediting_446544chr5_171398615_+SINEAluAluSc
CAediting_446545chr5_171398618_+SINEAluAluSc
CAediting_446546chr5_171398624_+SINEAluAluSc
CAediting_446547chr5_171398632_+SINEAluAluSc
CAediting_446548chr5_171398637_+SINEAluAluSc
CAediting_446549chr5_171398650_+SINEAluAluSc
CAediting_446550chr5_171398660_+SINEAluAluSc
CAediting_446551chr5_171398704_+SINEAluAluSc
CAediting_446552chr5_171398706_+SINEAluAluSc
CAediting_446553chr5_171398903_+SINEAluAluSx1
CAediting_446554chr5_171398913_+SINEAluAluSx1
CAediting_446555chr5_171398980_+SINEAluAluSx1
CAediting_446556chr5_171398990_+SINEAluAluSx1
CAediting_446557chr5_171398992_+SINEAluAluSx1
CAediting_446558chr5_171399016_+SINEAluAluSx1
CAediting_446559chr5_171399071_+SINEAluAluSx1
CAediting_446560chr5_171399277_+SINEAluAluJr4
CAediting_446561chr5_171399348_+SINEAluAluJr4
CAediting_446562chr5_171399372_+SINEAluAluJr4
CAediting_446563chr5_171399379_+SINEAluAluJr4
CAediting_446564chr5_171399499_+SINEAluAluJr4
CAediting_446565chr5_171399505_+SINEAluAluJr4
CAediting_446566chr5_171400604_+SINEAluAluSg
CAediting_446567chr5_171401138_+SINEAluAluSx
CAediting_446568chr5_171401143_+SINEAluAluSx
CAediting_446569chr5_171401148_+SINEAluAluSx
CAediting_446570chr5_171401151_+SINEAluAluSx
CAediting_446571chr5_171401181_+SINEAluAluSx
CAediting_446572chr5_171401182_+SINEAluAluSx
CAediting_446573chr5_171401202_+SINEAluAluSx
CAediting_446574chr5_171401205_+SINEAluAluSx
CAediting_446575chr5_171401206_+SINEAluAluSx
CAediting_446576chr5_171401207_+SINEAluAluSx
CAediting_446577chr5_171401208_+SINEAluAluSx
CAediting_446578chr5_171401237_+SINEAluAluSx
CAediting_446579chr5_171401238_+SINEAluAluSx
CAediting_446580chr5_171401251_+SINEAluAluSx
CAediting_446581chr5_171401269_+SINEAluAluSx
CAediting_446582chr5_171401468_+SINEAluAluSx
CAediting_446583chr5_171401490_+SINEAluAluSx
CAediting_446584chr5_171401492_+SINEAluAluSx
CAediting_446585chr5_171401562_+SINEAluAluSx
CAediting_446586chr5_171401563_+SINEAluAluSx
CAediting_446587chr5_171401566_+SINEAluAluSx
CAediting_446588chr5_171401576_+SINEAluAluSx
CAediting_446589chr5_171401598_+SINEAluAluSx
CAediting_446590chr5_171401621_+SINEAluAluSx
CAediting_446591chr5_171401651_+SINEAluAluSx
CAediting_446592chr5_171401662_+SINEAluAluSx
CAediting_446593chr5_171401663_+SINEAluAluSx
CAediting_446594chr5_171401664_+SINEAluAluSx
CAediting_446595chr5_171401671_+SINEAluAluSx
CAediting_446596chr5_171401681_+SINEAluAluSx
CAediting_446597chr5_171404991_+SINEAluAluJo
CAediting_446598chr5_171404999_+SINEAluAluJo
CAediting_446599chr5_171405007_+SINEAluAluJo
CAediting_446600chr5_171405055_+SINEAluAluJo
CAediting_446601chr5_171405077_+SINEAluAluJo
CAediting_446602chr5_171405099_+SINEAluAluJo
CAediting_446604chr5_171409331_+SINEAluAluSz6
CAediting_446605chr5_171409336_+SINEAluAluSz6
CAediting_446606chr5_171409374_+SINEAluAluSz6
CAediting_446607chr5_171409387_+SINEAluAluSz6
CAediting_446608chr5_171409390_+SINEAluAluSz6
CAediting_446609chr5_171409391_+SINEAluAluSz6
CAediting_446610chr5_171409392_+SINEAluAluSz6
CAediting_446611chr5_171409393_+SINEAluAluSz6
CAediting_446612chr5_171409394_+SINEAluAluSz6
CAediting_446613chr5_171409396_+SINEAluAluSz6
CAediting_446614chr5_171409399_+SINEAluAluSz6
CAediting_446615chr5_171409405_+SINEAluAluSz6
CAediting_446616chr5_171409441_+SINEAluAluSz6
CAediting_446617chr5_171409445_+SINEAluAluSz6
CAediting_446618chr5_171409458_+SINEAluAluSz6
CAediting_446619chr5_171409473_+SINEAluAluSz6
CAediting_446620chr5_171409531_+SINEAluAluSz6
CAediting_446621chr5_171409752_+SINEAluAluSx
CAediting_446622chr5_171409869_+SINEAluAluSz
CAediting_446623chr5_171409894_+SINEAluAluSz
CAediting_446624chr5_171409898_+SINEAluAluSz
CAediting_446625chr5_171409907_+SINEAluAluSz
CAediting_446626chr5_171409947_+SINEAluAluSz
CAediting_446627chr5_171409954_+SINEAluAluSz
CAediting_446628chr5_171409963_+SINEAluAluSz
CAediting_446629chr5_171409964_+SINEAluAluSz
CAediting_446630chr5_171409972_+SINEAluAluSz
CAediting_446631chr5_171409978_+SINEAluAluSz
CAediting_446632chr5_171409981_+SINEAluAluSz
CAediting_446633chr5_171409983_+SINEAluAluSz
CAediting_446634chr5_171409985_+SINEAluAluSz
CAediting_446635chr5_171409993_+SINEAluAluSz
CAediting_446636chr5_171410031_+SINEAluAluSz
CAediting_446637chr5_171410070_+SINEAluAluSz
CAediting_446638chr5_171410072_+SINEAluAluSz
CAediting_446639chr5_171410079_+SINEAluAluSz

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RNA A-to-I editing events in the alternative splicing sites for NPM1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000181163.12.NPM1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000181163.12.NPM1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NPM1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for NPM1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for NPM1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_688081chr9_63819627_+ENSG00000181163.12ENST00000393820hsa-miR-4477b1714065831714065908mer-1a171406569171406590156-16.08
CAediting_86358chr1_109598906_+ENSG00000181163.12ENST00000517671hsa-miR-197-5p1714107521714107587mer-m8171410737171410759145-16.55
CAediting_86358chr1_109598906_+ENSG00000181163.12ENST00000351986hsa-miR-197-5p1714107521714107587mer-m8171410737171410759145-16.55

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NPM1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for NPM1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
TGCTCAediting_446624chr5_171409898_+0.005341457084936240.364273402552321....

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Relation with cancer stages for NPM1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
KIRCpathologic_stageCAediting_446624chr5_171409898_+0.00391949218879650.319051911709793
LUSCpathologic_stageCAediting_446624chr5_171409898_+0.04497540358838990.227693320428524

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Relation with survival for NPM1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for NPM1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for NPM1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
NPM1C0026998Acute Myeloid Leukemia, M16CTD_human;ORPHANET
NPM1C1879321Acute Myeloid Leukemia (AML-M2)6CTD_human;ORPHANET
NPM1C0023467Leukemia, Myelocytic, Acute5CGI;CTD_human
NPM1C0023487Acute Promyelocytic Leukemia2CGI;CTD_human;ORPHANET
NPM1C0024623Malignant neoplasm of stomach1CTD_human
NPM1C0038356Stomach Neoplasms1CTD_human
NPM1C0152013Adenocarcinoma of lung (disorder)1CTD_human
NPM1C0206182Lymphomatoid Papulosis1ORPHANET
NPM1C0265965Dyskeratosis Congenita1CTD_human;GENOMICS_ENGLAND
NPM1C1148551X-Linked Dyskeratosis Congenita1CTD_human
NPM1C1301362Primary Cutaneous Anaplastic Large Cell Lymphoma1ORPHANET
NPM1C1708349Hereditary Diffuse Gastric Cancer1CTD_human
NPM1C2930974Acute erythroleukemia1CTD_human
NPM1C2930975Acute erythroleukemia - M6a subtype1CTD_human
NPM1C2930976Acute myeloid leukemia FAB-M61CTD_human
NPM1C2930977Acute erythroleukemia - M6b subtype1CTD_human