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Editing gene: NFIX (CAeditome ID:4784)

Gene summary for NFIX

Gene summary

Gene information	Gene symbol	NFIX
	Gene ID	4784
	Gene name	nuclear factor I X
	Synonyms	CTF\|MRSHSS\|NF-I/X\|NF1-X\|NF1A\|SOTOS2
	Cytomap	19p13.13
	Type of gene	protein-coding
	Description	nuclear factor 1 X-typeCCAAT-box-binding transcription factorTGGCA-binding proteinnuclear factor 1/X
	Modification date	20210518
	UniProtAcc	Q14938
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
NFIX	GO:1990837	Nuclear factor 1 X-type	28473536
NFIX	GO:0000122	Nuclear factor 1 X-type	19706729
NFIX	GO:0045944	Nuclear factor 1 X-type	19706729

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RNA A-to-I events for NFIX

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000008441.15

RNA A-to-I editing events in Cancer.

CAediting_1303983(13025151, +), CAediting_1303984(13034944, +), CAediting_1303985(13037741, +), CAediting_1303986(13041674, +), CAediting_1303987(13041991, +), CAediting_1303988(13042424, +), CAediting_1303989(13042558, +), CAediting_1303990(13042610, +), CAediting_1303991(13048605, +), CAediting_1303992(13048818, +), CAediting_1303993(13058487, +), CAediting_1303994(13058679, +), CAediting_1303995(13080297, +), CAediting_1303996(13080311, +), CAediting_1303997(13080321, +), CAediting_1303998(13080338, +), CAediting_1303999(13080472, +), CAediting_1304000(13080487, +), CAediting_1304001(13080592, +), CAediting_1304002(13080614, +), CAediting_1304003(13080783, +), CAediting_1304004(13081496, +), CAediting_1304005(13084297, +), CAediting_1304006(13085015, +), CAediting_1304007(13094708, +), CAediting_1304008(13097367, +), CAediting_1304009(13097389, +), CAediting_1304010(13097455, +), CAediting_1304011(13097467, +), CAediting_1304012(13097528, +),

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RNA editing positional annotations for NFIX using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000358552.6	c.A167G	p.E56G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000360105.7	c.A167G	p.E56G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000397661.5	c.A158G	p.E53G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000585382.4	c.A17G	p.E6G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000585575.4	c.A134G	p.E45G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000586797.4	c.A169G	p.S57G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000586873.1	c.A17G	p.E6G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000587260.1	c.A155G	p.E52G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000587760.4	c.A134G	p.E45G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000588228.4	c.A17G	p.E6G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000590027.1	c.A17G	p.E6G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000591028.1	c.A206G	p.E69G	T	D	D
CAediting_1303983	chr19_13025151_+	nonsynonymous SNV	ENST00000592199.4	c.A158G	p.E53G	T	D	D

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1303983	chr19_13025151_+	exonic
CAediting_1303984	chr19_13034944_+	intronic
CAediting_1303985	chr19_13037741_+	intronic
CAediting_1303986	chr19_13041674_+	intronic
CAediting_1303987	chr19_13041991_+	intronic
CAediting_1303988	chr19_13042424_+	intronic
CAediting_1303989	chr19_13042558_+	intronic
CAediting_1303990	chr19_13042610_+	intronic
CAediting_1303991	chr19_13048605_+	intronic
CAediting_1303992	chr19_13048818_+	intronic
CAediting_1303993	chr19_13058487_+	intronic
CAediting_1303994	chr19_13058679_+	intronic
CAediting_1303995	chr19_13080297_+	intronic
CAediting_1303996	chr19_13080311_+	intronic
CAediting_1303997	chr19_13080321_+	intronic
CAediting_1303998	chr19_13080338_+	intronic
CAediting_1303999	chr19_13080472_+	intronic
CAediting_1304000	chr19_13080487_+	intronic
CAediting_1304001	chr19_13080592_+	intronic
CAediting_1304002	chr19_13080614_+	intronic
CAediting_1304003	chr19_13080783_+	intronic
CAediting_1304004	chr19_13081496_+	intronic
CAediting_1304005	chr19_13084297_+	intronic
CAediting_1304006	chr19_13085015_+	intronic
CAediting_1304007	chr19_13094708_+	UTR3
CAediting_1304008	chr19_13097367_+	UTR3
CAediting_1304009	chr19_13097389_+	UTR3
CAediting_1304010	chr19_13097455_+	UTR3
CAediting_1304011	chr19_13097467_+	UTR3
CAediting_1304012	chr19_13097528_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1303984	chr19_13034944_+	DNA	hAT-Charlie	MER20
CAediting_1303985	chr19_13037741_+	DNA	hAT-Charlie	MER20
CAediting_1303986	chr19_13041674_+	SINE	Alu	AluSg
CAediting_1303987	chr19_13041991_+	SINE	Alu	AluY
CAediting_1303988	chr19_13042424_+	SINE	Alu	AluSz6
CAediting_1303989	chr19_13042558_+	SINE	Alu	AluSz6
CAediting_1303990	chr19_13042610_+	SINE	Alu	AluSz6
CAediting_1303991	chr19_13048605_+	SINE	Alu	AluJr4
CAediting_1303992	chr19_13048818_+	SINE	Alu	AluSz
CAediting_1303993	chr19_13058487_+	SINE	Alu	AluJo
CAediting_1303994	chr19_13058679_+	SINE	Alu	AluJo
CAediting_1303995	chr19_13080297_+	SINE	Alu	AluJr
CAediting_1303996	chr19_13080311_+	SINE	Alu	AluJr
CAediting_1303997	chr19_13080321_+	SINE	Alu	AluJr
CAediting_1303998	chr19_13080338_+	SINE	Alu	AluJr
CAediting_1303999	chr19_13080472_+	SINE	Alu	AluJr
CAediting_1304000	chr19_13080487_+	SINE	Alu	AluJr
CAediting_1304001	chr19_13080592_+	SINE	Alu	AluJo
CAediting_1304002	chr19_13080614_+	SINE	Alu	AluJo
CAediting_1304003	chr19_13080783_+	SINE	Alu	AluY
CAediting_1304004	chr19_13081496_+	DNA	hAT-Tip100	MER96B
CAediting_1304005	chr19_13084297_+	SINE	Alu	AluSx3
CAediting_1304006	chr19_13085015_+	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for NFIX

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000008441.15.NFIX.

Correlation between RNA A-to-I editing and PSI for ENSG00000008441.15.NFIX.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NFIX

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for NFIX

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for NFIX

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000397661	hsa-miR-3059-5p	13094704	13094711	8mer-1a	13094688	13094711	165.00	-27.80
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000397661	hsa-miR-6845-3p	13094702	13094707	6mer	13094688	13094708	146.00	-27.97
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000397661	hsa-miR-6881-3p	13094704	13094710	7mer-1a	13094690	13094710	146.00	-19.22
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000397661	hsa-miR-7111-3p	13094703	13094710	8mer-1a	13094689	13094710	162.00	-24.73
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587760	hsa-miR-3059-5p	13094704	13094711	8mer-1a	13094688	13094711	165.00	-27.80
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587760	hsa-miR-6845-3p	13094702	13094707	6mer	13094688	13094708	146.00	-27.97
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587760	hsa-miR-6881-3p	13094704	13094710	7mer-1a	13094690	13094710	146.00	-19.22
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587760	hsa-miR-7111-3p	13094703	13094710	8mer-1a	13094689	13094710	162.00	-24.73
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000358552	hsa-miR-3059-5p	13094704	13094711	8mer-1a	13094688	13094711	165.00	-27.80
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000358552	hsa-miR-6845-3p	13094702	13094707	6mer	13094688	13094708	146.00	-27.97
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000358552	hsa-miR-6881-3p	13094704	13094710	7mer-1a	13094690	13094710	146.00	-19.22
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000358552	hsa-miR-7111-3p	13094703	13094710	8mer-1a	13094689	13094710	162.00	-24.73
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000360105	hsa-miR-3059-5p	13094704	13094711	8mer-1a	13094688	13094711	165.00	-27.80
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000360105	hsa-miR-6845-3p	13094702	13094707	6mer	13094688	13094708	146.00	-27.97
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000360105	hsa-miR-6881-3p	13094704	13094710	7mer-1a	13094690	13094710	146.00	-19.22
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000360105	hsa-miR-7111-3p	13094703	13094710	8mer-1a	13094689	13094710	162.00	-24.73
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000588228	hsa-miR-3059-5p	13094704	13094711	8mer-1a	13094688	13094711	165.00	-27.80
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000588228	hsa-miR-6845-3p	13094702	13094707	6mer	13094688	13094708	146.00	-27.97
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000588228	hsa-miR-6881-3p	13094704	13094710	7mer-1a	13094690	13094710	146.00	-19.22
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000588228	hsa-miR-7111-3p	13094703	13094710	8mer-1a	13094689	13094710	162.00	-24.73
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587260	hsa-miR-3059-5p	13094704	13094711	8mer-1a	13094688	13094711	165.00	-27.80
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587260	hsa-miR-6845-3p	13094702	13094707	6mer	13094688	13094708	146.00	-27.97
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587260	hsa-miR-6881-3p	13094704	13094710	7mer-1a	13094690	13094710	146.00	-19.22
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587260	hsa-miR-7111-3p	13094703	13094710	8mer-1a	13094689	13094710	162.00	-24.73
CAediting_1304008	chr19_13097367_+	ENSG00000008441.15	ENST00000360105	hsa-miR-1247-5p	13097361	13097368	8mer-1a	13097347	13097368	151.00	-18.86
CAediting_1304008	chr19_13097367_+	ENSG00000008441.15	ENST00000360105	hsa-miR-629-3p	13097365	13097372	8mer-1a	13097351	13097372	142.00	-14.46
CAediting_1304010	chr19_13097455_+	ENSG00000008441.15	ENST00000360105	hsa-let-7c-3p	13097452	13097458	7mer-m8	13097436	13097459	143.00	-6.59
CAediting_1304011	chr19_13097467_+	ENSG00000008441.15	ENST00000360105	hsa-miR-4719	13097463	13097469	7mer-1a	13097449	13097469	140.00	-10.47

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000397661	hsa-miR-4659a-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000397661	hsa-miR-4659b-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000397661	hsa-miR-629-3p	13094701	13094707	7mer-m8	13094687	13094708	141	-14.46
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587760	hsa-miR-4659a-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587760	hsa-miR-4659b-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587760	hsa-miR-629-3p	13094701	13094707	7mer-m8	13094687	13094708	141	-14.46
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000358552	hsa-miR-4659a-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000358552	hsa-miR-4659b-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000358552	hsa-miR-629-3p	13094701	13094707	7mer-m8	13094687	13094708	141	-14.46
CAediting_1304010	chr19_13097455_+	ENSG00000008441.15	ENST00000360105	hsa-miR-374a-5p	13097450	13097456	7mer-m8	13097436	13097457	140	-1.89
CAediting_1304010	chr19_13097455_+	ENSG00000008441.15	ENST00000360105	hsa-miR-374b-5p	13097450	13097456	7mer-m8	13097436	13097457	140	-2.24
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000360105	hsa-miR-4659a-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000360105	hsa-miR-4659b-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304008	chr19_13097367_+	ENSG00000008441.15	ENST00000360105	hsa-miR-4768-5p	13097365	13097372	8mer-1a	13097351	13097372	140	-11.39
CAediting_1304010	chr19_13097455_+	ENSG00000008441.15	ENST00000360105	hsa-miR-568	13097452	13097458	7mer-m8	13097440	13097459	146	-6.88
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000360105	hsa-miR-629-3p	13094701	13094707	7mer-m8	13094687	13094708	141	-14.46
CAediting_1304010	chr19_13097455_+	ENSG00000008441.15	ENST00000360105	hsa-miR-633	13097448	13097454	7mer-m8	13097433	13097455	144	-4.41
CAediting_1304008	chr19_13097367_+	ENSG00000008441.15	ENST00000360105	hsa-miR-6809-3p	13097366	13097372	7mer-1a	13097352	13097372	146	-14.16
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000588228	hsa-miR-4659a-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000588228	hsa-miR-4659b-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000588228	hsa-miR-629-3p	13094701	13094707	7mer-m8	13094687	13094708	141	-14.46
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587260	hsa-miR-4659a-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587260	hsa-miR-4659b-3p	13094704	13094711	8mer-1a	13094690	13094711	141	-12.79
CAediting_1304007	chr19_13094708_+	ENSG00000008441.15	ENST00000587260	hsa-miR-629-3p	13094701	13094707	7mer-m8	13094687	13094708	141	-14.46

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000008441.15	ENST00000397661	hsa-miR-605-3p	13095573	13095579	7mer-m8	13095561	13095580	148	-20.1
CAediting_748296	chr10_51299626_+	ENSG00000008441.15	ENST00000585382	hsa-miR-605-3p	13078655	13078661	7mer-m8	13078640	13078662	159	-27.17
CAediting_748296	chr10_51299626_+	ENSG00000008441.15	ENST00000360105	hsa-miR-605-3p	13098542	13098548	7mer-m8	13098529	13098549	146	-16.42
CAediting_748296	chr10_51299626_+	ENSG00000008441.15	ENST00000360105	hsa-miR-605-3p	13095573	13095579	7mer-m8	13095561	13095580	148	-20.1
CAediting_393	chr1_1167164_+	ENSG00000008441.15	ENST00000360105	hsa-miR-200b-3p	13097769	13097776	8mer-1a	13097755	13097776	140	-13.09
CAediting_748296	chr10_51299626_+	ENSG00000008441.15	ENST00000586797	hsa-miR-605-3p	13078655	13078661	7mer-m8	13078640	13078662	159	-27.17
CAediting_1054808	chr15_66496985_-	ENSG00000008441.15	ENST00000397661	hsa-miR-4512	13095469	13095475	7mer-m8	13095455	13095476	140	-19.09
CAediting_1368054	chr19_46709310_-	ENSG00000008441.15	ENST00000397661	hsa-miR-320e	13096098	13096104	7mer-m8	13096087	13096105	147	-18.76
CAediting_86358	chr1_109598906_+	ENSG00000008441.15	ENST00000397661	hsa-miR-197-5p	13095050	13095056	7mer-m8	13095037	13095057	149	-22.17
CAediting_396018	chr5_1062918_-	ENSG00000008441.15	ENST00000397661	hsa-miR-4635	13096022	13096028	7mer-m8	13096009	13096029	141	-13.8
CAediting_580943	chr7_100356700_+	ENSG00000008441.15	ENST00000585382	hsa-miR-6840-3p	13075600	13075607	8mer-1a	13075586	13075607	141	-20.09
CAediting_604450	chr7_133034877_-	ENSG00000008441.15	ENST00000585382	hsa-miR-3654	13075639	13075645	7mer-m8	13075628	13075646	154	-21.79
CAediting_1229415	chr17_67471547_+	ENSG00000008441.15	ENST00000585382	hsa-miR-548aa	13078687	13078693	7mer-m8	13078670	13078694	140	-12.7
CAediting_1054808	chr15_66496985_-	ENSG00000008441.15	ENST00000360105	hsa-miR-4512	13096588	13096594	7mer-m8	13096573	13096595	159	-36.89
CAediting_1054808	chr15_66496985_-	ENSG00000008441.15	ENST00000360105	hsa-miR-4512	13095469	13095475	7mer-m8	13095455	13095476	140	-19.09
CAediting_1160181	chr17_7017644_-	ENSG00000008441.15	ENST00000360105	hsa-miR-195-3p	13096274	13096280	7mer-m8	13096262	13096281	152	-15.59
CAediting_1368054	chr19_46709310_-	ENSG00000008441.15	ENST00000360105	hsa-miR-320e	13096098	13096104	7mer-m8	13096087	13096105	147	-18.76
CAediting_86358	chr1_109598906_+	ENSG00000008441.15	ENST00000360105	hsa-miR-197-5p	13095050	13095056	7mer-m8	13095037	13095057	149	-22.17
CAediting_1399425	chr20_1392958_-	ENSG00000008441.15	ENST00000360105	hsa-miR-6869-5p	13096433	13096439	7mer-m8	13096420	13096440	156	-27.06
CAediting_396018	chr5_1062918_-	ENSG00000008441.15	ENST00000360105	hsa-miR-4635	13096022	13096028	7mer-m8	13096009	13096029	141	-13.8
CAediting_580943	chr7_100356700_+	ENSG00000008441.15	ENST00000360105	hsa-miR-6840-3p	13096569	13096575	7mer-m8	13096554	13096576	155	-31.97
CAediting_580943	chr7_100356700_+	ENSG00000008441.15	ENST00000360105	hsa-miR-6840-3p	13098338	13098345	8mer-1a	13098321	13098345	147	-33.59
CAediting_442554	chr5_154685830_+	ENSG00000008441.15	ENST00000586797	hsa-miR-1303	13025306	13025312	7mer-m8	13025292	13025313	140	-15.19
CAediting_604450	chr7_133034877_-	ENSG00000008441.15	ENST00000586797	hsa-miR-3654	13025479	13025485	7mer-m8	13025470	13025486	146	-21.93
CAediting_580943	chr7_100356700_+	ENSG00000008441.15	ENST00000586797	hsa-miR-6840-3p	13075600	13075607	8mer-1a	13075586	13075607	141	-20.09
CAediting_604450	chr7_133034877_-	ENSG00000008441.15	ENST00000586797	hsa-miR-3654	13075639	13075645	7mer-m8	13075628	13075646	154	-21.79
CAediting_1229415	chr17_67471547_+	ENSG00000008441.15	ENST00000586797	hsa-miR-548aa	13078687	13078693	7mer-m8	13078670	13078694	140	-12.7
CAediting_468389	chr6_31355314_-	ENSG00000008441.15	ENST00000397661	hsa-miR-6891-5p	13095943	13095948	6mer	13095934	13095952	146	-17.75
CAediting_468389	chr6_31355314_-	ENSG00000008441.15	ENST00000397661	hsa-miR-6891-5p	13095945	13095951	7mer-m8	13095934	13095952	146	-17.75
CAediting_1524209	chrX_134546392_-	ENSG00000008441.15	ENST00000397661	hsa-miR-503-5p	13095697	13095703	7mer-m8	13095683	13095704	150	-23.59
CAediting_1524209	chrX_134546392_-	ENSG00000008441.15	ENST00000585382	hsa-miR-503-5p	13078705	13078711	7mer-m8	13078690	13078712	150	-22.09
CAediting_468389	chr6_31355314_-	ENSG00000008441.15	ENST00000360105	hsa-miR-6891-5p	13095943	13095948	6mer	13095934	13095952	146	-17.75
CAediting_468389	chr6_31355314_-	ENSG00000008441.15	ENST00000360105	hsa-miR-6891-5p	13095945	13095951	7mer-m8	13095934	13095952	146	-17.75
CAediting_468389	chr6_31355314_-	ENSG00000008441.15	ENST00000360105	hsa-miR-6891-5p	13097614	13097620	7mer-m8	13097602	13097621	155	-31.43
CAediting_1524209	chrX_134546392_-	ENSG00000008441.15	ENST00000360105	hsa-miR-503-5p	13095697	13095703	7mer-m8	13095683	13095704	150	-23.59
CAediting_1524209	chrX_134546392_-	ENSG00000008441.15	ENST00000586797	hsa-miR-503-5p	13078705	13078711	7mer-m8	13078690	13078712	150	-22.09
CAediting_468389	chr6_31355314_-	ENSG00000008441.15	ENST00000586797	hsa-miR-6891-5p	13090316	13090322	7mer-m8	13090305	13090323	146	-18.06

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1368054	chr19_46709310_-	ENSG00000008441.15	ENST00000397661	hsa-miR-320e	13095121	13095127	7mer-m8	13095111	13095128	140	-17.1
CAediting_748296	chr10_51299626_+	ENSG00000008441.15	ENST00000397661	hsa-miR-605-3p	13094958	13094964	7mer-m8	13094944	13094965	143	-12.16
CAediting_468389	chr6_31355314_-	ENSG00000008441.15	ENST00000397661	hsa-miR-6891-5p	13095505	13095511	7mer-m8	13095494	13095512	140	-16.33
CAediting_1368054	chr19_46709310_-	ENSG00000008441.15	ENST00000360105	hsa-miR-320e	13095121	13095127	7mer-m8	13095111	13095128	140	-17.1
CAediting_524911	chr7_5495852_-	ENSG00000008441.15	ENST00000360105	hsa-miR-589-3p	13095356	13095363	8mer-1a	13095341	13095363	149	-18.34
CAediting_748296	chr10_51299626_+	ENSG00000008441.15	ENST00000360105	hsa-miR-605-3p	13094958	13094964	7mer-m8	13094944	13094965	143	-12.16
CAediting_980496	chr14_31014685_-	ENSG00000008441.15	ENST00000360105	hsa-miR-624-3p	13098058	13098063	6mer	13098044	13098064	141	-18.19
CAediting_468389	chr6_31355314_-	ENSG00000008441.15	ENST00000360105	hsa-miR-6891-5p	13095505	13095511	7mer-m8	13095494	13095512	140	-16.33

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NFIX

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for NFIX

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for NFIX

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for NFIX

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for NFIX

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for NFIX

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
NFIX	C3553660	Malan overgrowth syndrome	5	GENOMICS_ENGLAND;ORPHANET;UNIPROT
NFIX	C0265211	Marshall-Smith syndrome	2	CTD_human;GENOMICS_ENGLAND;ORPHANET
NFIX	C0005586	Bipolar Disorder	1	PSYGENET

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene