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Editing gene: NDUFB2 (CAeditome ID:4708)

Gene summary for NDUFB2

Gene summary

Gene information	Gene symbol	NDUFB2
	Gene ID	4708
	Gene name	NADH:ubiquinone oxidoreductase subunit B2
	Synonyms	AGGG\|CI-AGGG
	Cytomap	7q34
	Type of gene	protein-coding
	Description	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrialNADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDaNADH-ubiquinone oxidoreductase AGGG subunitcomplex I AGGG subunitcomplex I-AGGG
	Modification date	20210518
	UniProtAcc	O95178
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
NDUFB2	GO:0005747	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial	12611891
NDUFB2	GO:0005747	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial	27626371

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RNA A-to-I events for NDUFB2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000090266.11

RNA A-to-I editing events in Cancer.

CAediting_608940(140692381, +), CAediting_608941(140692413, +), CAediting_608942(140692457, +), CAediting_608943(140692487, +), CAediting_608944(140692488, +), CAediting_608945(140692504, +), CAediting_608946(140693735, +), CAediting_608947(140693741, +), CAediting_608948(140693760, +), CAediting_608949(140693790, +), CAediting_608950(140693804, +), CAediting_608951(140693809, +), CAediting_608952(140693836, +), CAediting_608953(140693839, +), CAediting_608954(140693900, +), CAediting_608955(140693916, +), CAediting_608956(140693970, +), CAediting_608957(140693971, +), CAediting_608958(140694063, +), CAediting_608959(140694065, +), CAediting_608960(140694066, +), CAediting_608961(140694087, +), CAediting_608962(140694088, +), CAediting_608963(140694095, +), CAediting_608964(140694111, +), CAediting_608965(140694180, +), CAediting_608966(140694186, +), CAediting_608967(140694190, +), CAediting_608968(140694203, +), CAediting_608969(140694204, +), CAediting_608970(140694209, +), CAediting_608971(140694229, +), CAediting_608972(140694249, +), CAediting_608973(140694259, +), CAediting_608974(140694266, +), CAediting_608975(140697854, +), CAediting_608976(140697865, +), CAediting_608977(140697866, +), CAediting_608978(140697874, +), CAediting_608979(140697904, +), CAediting_608980(140697914, +), CAediting_608981(140697935, +), CAediting_608982(140697962, +), CAediting_608983(140698896, +), CAediting_608984(140698993, +), CAediting_608985(140699069, +), CAediting_608986(140699078, +), CAediting_608987(140699083, +), CAediting_608988(140699099, +), CAediting_608989(140699108, +), CAediting_608990(140700146, +), CAediting_608991(140700149, +), CAediting_608992(140700201, +), CAediting_608993(140700345, +), CAediting_608994(140700386, +), CAediting_608995(140700574, +), CAediting_608996(140700579, +), CAediting_608997(140700642, +), CAediting_608998(140700729, +), CAediting_608999(140700737, +), CAediting_609000(140700738, +), CAediting_609001(140701477, +), CAediting_609002(140701524, +), CAediting_609003(140701530, +), CAediting_609004(140701534, +), CAediting_609005(140701553, +), CAediting_609006(140701589, +), CAediting_609007(140701590, +), CAediting_609008(140701595, +), CAediting_609009(140701678, +), CAediting_609010(140701723, +), CAediting_609011(140701732, +), CAediting_609012(140701768, +), CAediting_609013(140701815, +), CAediting_609014(140701856, +), CAediting_609015(140701857, +), CAediting_609016(140701861, +), CAediting_609017(140701877, +), CAediting_609018(140701881, +), CAediting_609019(140701885, +), CAediting_609020(140701948, +), CAediting_609021(140701951, +), CAediting_609022(140706113, +), CAediting_609023(140706117, +), CAediting_609024(140706139, +), CAediting_609025(140706144, +), CAediting_609026(140706171, +), CAediting_609027(140706185, +), CAediting_609028(140706190, +), CAediting_609029(140706191, +), CAediting_609030(140706195, +), CAediting_609031(140706261, +), CAediting_609032(140706293, +), CAediting_609033(140706298, +), CAediting_609034(140706313, +), CAediting_609035(140706337, +), CAediting_609036(140706338, +), CAediting_609037(140706350, +), CAediting_609038(140706352, +),

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RNA editing positional annotations for NDUFB2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_608940	chr7_140692381_+	intronic
CAediting_608941	chr7_140692413_+	intronic
CAediting_608942	chr7_140692457_+	intronic
CAediting_608943	chr7_140692487_+	intronic
CAediting_608944	chr7_140692488_+	intronic
CAediting_608945	chr7_140692504_+	intronic
CAediting_608946	chr7_140693735_+	intronic
CAediting_608947	chr7_140693741_+	intronic
CAediting_608948	chr7_140693760_+	intronic
CAediting_608949	chr7_140693790_+	intronic
CAediting_608950	chr7_140693804_+	intronic
CAediting_608951	chr7_140693809_+	intronic
CAediting_608952	chr7_140693836_+	intronic
CAediting_608953	chr7_140693839_+	intronic
CAediting_608954	chr7_140693900_+	intronic
CAediting_608955	chr7_140693916_+	intronic
CAediting_608956	chr7_140693970_+	intronic
CAediting_608957	chr7_140693971_+	intronic
CAediting_608958	chr7_140694063_+	intronic
CAediting_608959	chr7_140694065_+	intronic
CAediting_608960	chr7_140694066_+	intronic
CAediting_608961	chr7_140694087_+	intronic
CAediting_608962	chr7_140694088_+	intronic
CAediting_608963	chr7_140694095_+	intronic
CAediting_608964	chr7_140694111_+	intronic
CAediting_608965	chr7_140694180_+	intronic
CAediting_608966	chr7_140694186_+	intronic
CAediting_608967	chr7_140694190_+	intronic
CAediting_608968	chr7_140694203_+	intronic
CAediting_608969	chr7_140694204_+	intronic
CAediting_608970	chr7_140694209_+	intronic
CAediting_608971	chr7_140694229_+	intronic
CAediting_608972	chr7_140694249_+	intronic
CAediting_608973	chr7_140694259_+	intronic
CAediting_608974	chr7_140694266_+	intronic
CAediting_608975	chr7_140697854_+	ncRNA_intronic
CAediting_608976	chr7_140697865_+	ncRNA_intronic
CAediting_608977	chr7_140697866_+	ncRNA_intronic
CAediting_608978	chr7_140697874_+	ncRNA_intronic
CAediting_608979	chr7_140697904_+	ncRNA_intronic
CAediting_608980	chr7_140697914_+	ncRNA_intronic
CAediting_608981	chr7_140697935_+	ncRNA_intronic
CAediting_608982	chr7_140697962_+	ncRNA_intronic
CAediting_608983	chr7_140698896_+	ncRNA_intronic
CAediting_608984	chr7_140698993_+	ncRNA_intronic
CAediting_608985	chr7_140699069_+	ncRNA_intronic
CAediting_608986	chr7_140699078_+	ncRNA_intronic
CAediting_608987	chr7_140699083_+	ncRNA_intronic
CAediting_608988	chr7_140699099_+	ncRNA_intronic
CAediting_608989	chr7_140699108_+	ncRNA_intronic
CAediting_608990	chr7_140700146_+	ncRNA_intronic
CAediting_608991	chr7_140700149_+	ncRNA_intronic
CAediting_608992	chr7_140700201_+	ncRNA_exonic
CAediting_608993	chr7_140700345_+	ncRNA_intronic
CAediting_608994	chr7_140700386_+	ncRNA_intronic
CAediting_608995	chr7_140700574_+	ncRNA_intronic
CAediting_608996	chr7_140700579_+	ncRNA_intronic
CAediting_608997	chr7_140700642_+	ncRNA_intronic
CAediting_608998	chr7_140700729_+	ncRNA_exonic
CAediting_608999	chr7_140700737_+	ncRNA_exonic
CAediting_609000	chr7_140700738_+	ncRNA_exonic
CAediting_609001	chr7_140701477_+	ncRNA_intronic
CAediting_609002	chr7_140701524_+	ncRNA_intronic
CAediting_609003	chr7_140701530_+	ncRNA_intronic
CAediting_609004	chr7_140701534_+	ncRNA_intronic
CAediting_609005	chr7_140701553_+	ncRNA_intronic
CAediting_609006	chr7_140701589_+	ncRNA_intronic
CAediting_609007	chr7_140701590_+	ncRNA_intronic
CAediting_609008	chr7_140701595_+	ncRNA_intronic
CAediting_609009	chr7_140701678_+	ncRNA_intronic
CAediting_609010	chr7_140701723_+	ncRNA_intronic
CAediting_609011	chr7_140701732_+	ncRNA_intronic
CAediting_609012	chr7_140701768_+	ncRNA_intronic
CAediting_609013	chr7_140701815_+	ncRNA_intronic
CAediting_609014	chr7_140701856_+	ncRNA_intronic
CAediting_609015	chr7_140701857_+	ncRNA_intronic
CAediting_609016	chr7_140701861_+	ncRNA_intronic
CAediting_609017	chr7_140701877_+	ncRNA_intronic
CAediting_609018	chr7_140701881_+	ncRNA_intronic
CAediting_609019	chr7_140701885_+	ncRNA_intronic
CAediting_609020	chr7_140701948_+	ncRNA_intronic
CAediting_609021	chr7_140701951_+	ncRNA_intronic
CAediting_609022	chr7_140706113_+	ncRNA_intronic
CAediting_609023	chr7_140706117_+	splicing
CAediting_609024	chr7_140706139_+	ncRNA_intronic
CAediting_609025	chr7_140706144_+	ncRNA_intronic
CAediting_609026	chr7_140706171_+	ncRNA_intronic
CAediting_609027	chr7_140706185_+	ncRNA_intronic
CAediting_609028	chr7_140706190_+	ncRNA_intronic
CAediting_609029	chr7_140706191_+	ncRNA_intronic
CAediting_609030	chr7_140706195_+	ncRNA_intronic
CAediting_609031	chr7_140706261_+	ncRNA_intronic
CAediting_609032	chr7_140706293_+	ncRNA_intronic
CAediting_609033	chr7_140706298_+	ncRNA_intronic
CAediting_609034	chr7_140706313_+	ncRNA_intronic
CAediting_609035	chr7_140706337_+	ncRNA_intronic
CAediting_609036	chr7_140706338_+	ncRNA_intronic
CAediting_609037	chr7_140706350_+	ncRNA_intronic
CAediting_609038	chr7_140706352_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_608940	chr7_140692381_+	SINE	Alu	AluSz6
CAediting_608941	chr7_140692413_+	SINE	Alu	AluSz6
CAediting_608942	chr7_140692457_+	SINE	Alu	AluSz6
CAediting_608943	chr7_140692487_+	SINE	Alu	AluSz6
CAediting_608944	chr7_140692488_+	SINE	Alu	AluSz6
CAediting_608945	chr7_140692504_+	SINE	Alu	AluSz6
CAediting_608946	chr7_140693735_+	SINE	Alu	AluYh3
CAediting_608947	chr7_140693741_+	SINE	Alu	AluYh3
CAediting_608948	chr7_140693760_+	SINE	Alu	AluYh3
CAediting_608949	chr7_140693790_+	SINE	Alu	AluYh3
CAediting_608950	chr7_140693804_+	SINE	Alu	AluYh3
CAediting_608951	chr7_140693809_+	SINE	Alu	AluYh3
CAediting_608952	chr7_140693836_+	SINE	Alu	AluYh3
CAediting_608953	chr7_140693839_+	SINE	Alu	AluYh3
CAediting_608954	chr7_140693900_+	SINE	Alu	AluYh3
CAediting_608955	chr7_140693916_+	SINE	Alu	AluYh3
CAediting_608956	chr7_140693970_+	SINE	Alu	AluYh3
CAediting_608957	chr7_140693971_+	SINE	Alu	AluYh3
CAediting_608958	chr7_140694063_+	SINE	Alu	AluJr
CAediting_608959	chr7_140694065_+	SINE	Alu	AluJr
CAediting_608960	chr7_140694066_+	SINE	Alu	AluJr
CAediting_608961	chr7_140694087_+	SINE	Alu	AluJr
CAediting_608962	chr7_140694088_+	SINE	Alu	AluJr
CAediting_608963	chr7_140694095_+	SINE	Alu	AluJr
CAediting_608964	chr7_140694111_+	SINE	Alu	AluJr
CAediting_608965	chr7_140694180_+	SINE	Alu	AluJr
CAediting_608966	chr7_140694186_+	SINE	Alu	AluJr
CAediting_608967	chr7_140694190_+	SINE	Alu	AluJr
CAediting_608968	chr7_140694203_+	SINE	Alu	AluJr
CAediting_608969	chr7_140694204_+	SINE	Alu	AluJr
CAediting_608970	chr7_140694209_+	SINE	Alu	AluJr
CAediting_608971	chr7_140694229_+	SINE	Alu	AluJr
CAediting_608972	chr7_140694249_+	SINE	Alu	AluJr
CAediting_608973	chr7_140694259_+	SINE	Alu	AluJr
CAediting_608974	chr7_140694266_+	SINE	Alu	AluJr
CAediting_608975	chr7_140697854_+	SINE	Alu	FRAM
CAediting_608976	chr7_140697865_+	SINE	Alu	FRAM
CAediting_608977	chr7_140697866_+	SINE	Alu	FRAM
CAediting_608978	chr7_140697874_+	SINE	Alu	FRAM
CAediting_608979	chr7_140697904_+	SINE	Alu	FRAM
CAediting_608980	chr7_140697914_+	SINE	Alu	FRAM
CAediting_608981	chr7_140697935_+	SINE	Alu	FRAM
CAediting_608982	chr7_140697962_+	SINE	Alu	FRAM
CAediting_608983	chr7_140698896_+	SINE	Alu	AluSx
CAediting_608984	chr7_140698993_+	SINE	Alu	AluSx
CAediting_608985	chr7_140699069_+	SINE	Alu	AluSx
CAediting_608986	chr7_140699078_+	SINE	Alu	AluSx
CAediting_608987	chr7_140699083_+	SINE	Alu	AluSx
CAediting_608988	chr7_140699099_+	SINE	Alu	AluSx
CAediting_608989	chr7_140699108_+	SINE	Alu	AluSx
CAediting_608990	chr7_140700146_+	SINE	Alu	AluSp
CAediting_608991	chr7_140700149_+	SINE	Alu	AluSp
CAediting_608992	chr7_140700201_+	SINE	Alu	AluSp
CAediting_608993	chr7_140700345_+	SINE	Alu	AluSp
CAediting_608994	chr7_140700386_+	SINE	Alu	AluSp
CAediting_608995	chr7_140700574_+	SINE	Alu	AluSx
CAediting_608996	chr7_140700579_+	SINE	Alu	AluSx
CAediting_608997	chr7_140700642_+	SINE	Alu	AluSx
CAediting_608998	chr7_140700729_+	SINE	Alu	AluSx
CAediting_608999	chr7_140700737_+	SINE	Alu	AluSx
CAediting_609000	chr7_140700738_+	SINE	Alu	AluSx
CAediting_609001	chr7_140701477_+	SINE	Alu	AluJo
CAediting_609002	chr7_140701524_+	SINE	Alu	AluJo
CAediting_609003	chr7_140701530_+	SINE	Alu	AluJo
CAediting_609004	chr7_140701534_+	SINE	Alu	AluJo
CAediting_609005	chr7_140701553_+	SINE	Alu	AluJo
CAediting_609006	chr7_140701589_+	SINE	Alu	AluJo
CAediting_609007	chr7_140701590_+	SINE	Alu	AluJo
CAediting_609008	chr7_140701595_+	SINE	Alu	AluJo
CAediting_609009	chr7_140701678_+	SINE	Alu	AluSx
CAediting_609010	chr7_140701723_+	SINE	Alu	AluSx
CAediting_609011	chr7_140701732_+	SINE	Alu	AluSx
CAediting_609012	chr7_140701768_+	SINE	Alu	AluSx
CAediting_609013	chr7_140701815_+	SINE	Alu	AluSx
CAediting_609014	chr7_140701856_+	SINE	Alu	AluSx
CAediting_609015	chr7_140701857_+	SINE	Alu	AluSx
CAediting_609016	chr7_140701861_+	SINE	Alu	AluSx
CAediting_609017	chr7_140701877_+	SINE	Alu	AluSx
CAediting_609018	chr7_140701881_+	SINE	Alu	AluSx
CAediting_609019	chr7_140701885_+	SINE	Alu	AluSx
CAediting_609020	chr7_140701948_+	SINE	Alu	AluSx
CAediting_609021	chr7_140701951_+	SINE	Alu	AluSx
CAediting_609022	chr7_140706113_+	SINE	Alu	AluJb
CAediting_609023	chr7_140706117_+	SINE	Alu	AluJb
CAediting_609024	chr7_140706139_+	SINE	Alu	AluJb
CAediting_609025	chr7_140706144_+	SINE	Alu	AluJb
CAediting_609026	chr7_140706171_+	SINE	Alu	AluJb
CAediting_609027	chr7_140706185_+	SINE	Alu	AluJb
CAediting_609028	chr7_140706190_+	SINE	Alu	AluJb
CAediting_609029	chr7_140706191_+	SINE	Alu	AluJb
CAediting_609030	chr7_140706195_+	SINE	Alu	AluJb
CAediting_609031	chr7_140706261_+	SINE	Alu	AluJb
CAediting_609032	chr7_140706293_+	SINE	Alu	AluJb
CAediting_609033	chr7_140706298_+	SINE	Alu	AluJb
CAediting_609034	chr7_140706313_+	SINE	Alu	AluJb
CAediting_609035	chr7_140706337_+	SINE	Alu	AluJb
CAediting_609036	chr7_140706338_+	SINE	Alu	AluJb
CAediting_609037	chr7_140706350_+	SINE	Alu	AluJb
CAediting_609038	chr7_140706352_+	SINE	Alu	AluJb

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RNA A-to-I editing events in the alternative splicing sites for NDUFB2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000090266.11.NDUFB2.

Correlation between RNA A-to-I editing and PSI for ENSG00000090266.11.NDUFB2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NDUFB2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for NDUFB2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for NDUFB2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_609034	chr7_140706313_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3622a-3p	140706309	140706316	8mer-1a	140706296	140706316	145.00	-16.00
CAediting_609034	chr7_140706313_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3622b-3p	140706309	140706316	8mer-1a	140706297	140706316	151.00	-20.76
CAediting_609024	chr7_140706139_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3116	140706133	140706139	7mer-m8	140706118	140706140	159.00	-23.50
CAediting_609024	chr7_140706139_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3116	140706133	140706139	7mer-m8	140706118	140706140	159.00	-23.50
CAediting_609024	chr7_140706139_+	ENSG00000090266.11	ENST00000464566	hsa-miR-6512-3p	140706137	140706143	7mer-m8	140706123	140706144	144.00	-21.36
CAediting_609024	chr7_140706139_+	ENSG00000090266.11	ENST00000464566	hsa-miR-6720-5p	140706137	140706143	7mer-m8	140706123	140706144	152.00	-23.41
CAediting_609024	chr7_140706139_+	ENSG00000090266.11	ENST00000464566	hsa-miR-6849-3p	140706136	140706143	8mer-1a	140706122	140706143	148.00	-17.74
CAediting_609026	chr7_140706171_+	ENSG00000090266.11	ENST00000464566	hsa-miR-139-5p	140706164	140706170	7mer-m8	140706147	140706171	149.00	-19.37
CAediting_609026	chr7_140706171_+	ENSG00000090266.11	ENST00000464566	hsa-miR-4489	140706168	140706175	8mer-1a	140706153	140706175	158.00	-23.68
CAediting_609026	chr7_140706171_+	ENSG00000090266.11	ENST00000464566	hsa-miR-548v	140706165	140706171	7mer-m8	140706149	140706172	155.00	-14.34
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-665	140706178	140706184	7mer-m8	140706166	140706185	159.00	-22.52
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-6840-3p	140706179	140706185	7mer-m8	140706165	140706186	151.00	-26.21
CAediting_609029	chr7_140706191_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3622a-3p	140706187	140706194	8mer-1a	140706173	140706194	152.00	-17.60
CAediting_609029	chr7_140706191_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3622b-3p	140706187	140706194	8mer-1a	140706174	140706194	161.00	-24.61
CAediting_609036	chr7_140706338_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3189-3p	140706332	140706338	7mer-m8	140706318	140706339	148.00	-21.05
CAediting_609036	chr7_140706338_+	ENSG00000090266.11	ENST00000464566	hsa-miR-6813-3p	140706333	140706339	7mer-m8	140706320	140706340	140.00	-12.45
CAediting_609038	chr7_140706352_+	ENSG00000090266.11	ENST00000464566	hsa-miR-100-5p	140706348	140706354	7mer-m8	140706333	140706355	166.00	-23.64
CAediting_609038	chr7_140706352_+	ENSG00000090266.11	ENST00000464566	hsa-miR-99a-5p	140706348	140706354	7mer-m8	140706333	140706355	162.00	-23.78
CAediting_609038	chr7_140706352_+	ENSG00000090266.11	ENST00000464566	hsa-miR-99b-5p	140706348	140706354	7mer-m8	140706333	140706355	162.00	-29.13
CAediting_609030	chr7_140706195_+	ENSG00000090266.11	ENST00000464566	hsa-miR-1255b-2-3p	140706189	140706195	7mer-m8	140706178	140706196	142.00	-15.95
CAediting_609030	chr7_140706195_+	ENSG00000090266.11	ENST00000464566	hsa-miR-589-5p	140706193	140706199	7mer-m8	140706179	140706200	168.00	-22.61
CAediting_609032	chr7_140706293_+	ENSG00000090266.11	ENST00000464566	hsa-miR-4786-5p	140706290	140706297	8mer-1a	140706279	140706297	155.00	-25.86
CAediting_609032	chr7_140706293_+	ENSG00000090266.11	ENST00000464566	hsa-miR-6849-3p	140706286	140706292	7mer-m8	140706273	140706293	152.00	-18.03
CAediting_609035	chr7_140706337_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3192-5p	140706331	140706337	7mer-1a	140706316	140706337	147.00	-26.71
CAediting_609035	chr7_140706337_+	ENSG00000090266.11	ENST00000464566	hsa-miR-326	140706332	140706338	7mer-m8	140706320	140706339	140.00	-15.02
CAediting_609035	chr7_140706337_+	ENSG00000090266.11	ENST00000464566	hsa-miR-330-5p	140706332	140706338	7mer-m8	140706318	140706339	140.00	-20.29
CAediting_609035	chr7_140706337_+	ENSG00000090266.11	ENST00000464566	hsa-miR-4314	140706331	140706337	7mer-m8	140706320	140706338	146.00	-18.97
CAediting_609035	chr7_140706337_+	ENSG00000090266.11	ENST00000464566	hsa-miR-514a-5p	140706333	140706339	7mer-m8	140706318	140706340	151.00	-17.32
CAediting_609035	chr7_140706337_+	ENSG00000090266.11	ENST00000464566	hsa-miR-514a-5p	140706333	140706339	7mer-m8	140706318	140706340	151.00	-17.32
CAediting_609035	chr7_140706337_+	ENSG00000090266.11	ENST00000464566	hsa-miR-514a-5p	140706333	140706339	7mer-m8	140706318	140706340	151.00	-17.32

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_609031	chr7_140706261_+	ENSG00000090266.11	ENST00000464566	hsa-miR-1283	140706255	140706262	8mer-1a	140706241	140706262	145	-11.13
CAediting_609031	chr7_140706261_+	ENSG00000090266.11	ENST00000464566	hsa-miR-1283	140706255	140706262	8mer-1a	140706241	140706262	145	-11.13
CAediting_609026	chr7_140706171_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3170	140706169	140706176	8mer-1a	140706150	140706176	152	-18.11
CAediting_609030	chr7_140706195_+	ENSG00000090266.11	ENST00000464566	hsa-miR-34b-3p	140706190	140706196	7mer-m8	140706174	140706197	144	-8.53
CAediting_609034	chr7_140706313_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3614-5p	140706310	140706316	7mer-1a	140706295	140706316	141	-14.55
CAediting_609028	chr7_140706190_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3614-5p	140706188	140706194	7mer-1a	140706171	140706194	143	-15.67
CAediting_609029	chr7_140706191_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3614-5p	140706188	140706194	7mer-1a	140706171	140706194	143	-15.67
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3664-3p	140706179	140706185	7mer-m8	140706165	140706186	145	-17.05
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3670	140706182	140706189	8mer-1a	140706166	140706189	140	-9.86
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3670	140706182	140706189	8mer-1a	140706166	140706189	140	-9.86
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3670	140706182	140706189	8mer-1a	140706166	140706189	140	-9.86
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3670	140706182	140706189	8mer-1a	140706166	140706189	140	-9.86
CAediting_609031	chr7_140706261_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3675-3p	140706259	140706265	7mer-m8	140706245	140706266	149	-12.58
CAediting_609025	chr7_140706144_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3925-3p	140706138	140706144	7mer-m8	140706125	140706145	146	-15.01
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-3934-3p	140706180	140706186	7mer-m8	140706166	140706187	140	-17.18
CAediting_609035	chr7_140706337_+	ENSG00000090266.11	ENST00000464566	hsa-miR-450a-1-3p	140706330	140706337	8mer-1a	140706316	140706337	140	-10.02
CAediting_609024	chr7_140706139_+	ENSG00000090266.11	ENST00000464566	hsa-miR-4782-5p	140706132	140706138	7mer-m8	140706118	140706139	146	-14.65
CAediting_609025	chr7_140706144_+	ENSG00000090266.11	ENST00000464566	hsa-miR-508-5p	140706139	140706145	7mer-m8	140706124	140706146	146	-17.66
CAediting_609031	chr7_140706261_+	ENSG00000090266.11	ENST00000464566	hsa-miR-519a-2-5p	140706257	140706264	8mer-1a	140706244	140706264	145	-12.27
CAediting_609031	chr7_140706261_+	ENSG00000090266.11	ENST00000464566	hsa-miR-520b-5p	140706257	140706264	8mer-1a	140706244	140706264	145	-12.27
CAediting_609024	chr7_140706139_+	ENSG00000090266.11	ENST00000464566	hsa-miR-622	140706135	140706141	7mer-m8	140706124	140706142	148	-14.19
CAediting_609027	chr7_140706185_+	ENSG00000090266.11	ENST00000464566	hsa-miR-6854-5p	140706181	140706187	7mer-m8	140706163	140706188	146	-17.25
CAediting_609025	chr7_140706144_+	ENSG00000090266.11	ENST00000464566	hsa-miR-7703	140706142	140706148	7mer-m8	140706127	140706149	154	-19.4
CAediting_609034	chr7_140706313_+	ENSG00000090266.11	ENST00000464566	hsa-miR-8081	140706306	140706312	7mer-m8	140706290	140706313	147	-13.1

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229414	chr17_67471546_+	ENSG00000090266.11	ENST00000476279	hsa-miR-548aa	140722682	140722688	7mer-m8	140722665	140722689	145	-14.51
CAediting_86358	chr1_109598906_+	ENSG00000090266.11	ENST00000476279	hsa-miR-197-5p	140721830	140721836	7mer-m8	140721816	140721837	147	-22.44
CAediting_228905	chr2_188297554_+	ENSG00000090266.11	ENST00000476279	hsa-miR-561-3p	140721921	140721927	7mer-m8	140721907	140721928	153	-12.59
CAediting_228905	chr2_188297554_+	ENSG00000090266.11	ENST00000476279	hsa-miR-561-3p	140722288	140722294	7mer-m8	140722274	140722295	146	-9.64
CAediting_580943	chr7_100356700_+	ENSG00000090266.11	ENST00000476279	hsa-miR-6840-3p	140721898	140721905	8mer-1a	140721883	140721905	160	-28.98
CAediting_604450	chr7_133034877_-	ENSG00000090266.11	ENST00000476279	hsa-miR-3654	140721875	140721881	7mer-m8	140721864	140721882	141	-15.37
CAediting_86358	chr1_109598906_+	ENSG00000090266.11	ENST00000461457	hsa-miR-197-5p	140721830	140721836	7mer-m8	140721816	140721837	147	-22.44
CAediting_228905	chr2_188297554_+	ENSG00000090266.11	ENST00000461457	hsa-miR-561-3p	140721921	140721927	7mer-m8	140721907	140721928	153	-12.59
CAediting_580943	chr7_100356700_+	ENSG00000090266.11	ENST00000461457	hsa-miR-6840-3p	140721898	140721905	8mer-1a	140721883	140721905	160	-28.98
CAediting_604450	chr7_133034877_-	ENSG00000090266.11	ENST00000461457	hsa-miR-3654	140721875	140721881	7mer-m8	140721864	140721882	141	-15.37
CAediting_1229414	chr17_67471546_+	ENSG00000090266.11	ENST00000465506	hsa-miR-548aa	140705523	140705529	7mer-m8	140705506	140705530	140	-12.81
CAediting_396018	chr5_1062918_-	ENSG00000090266.11	ENST00000465506	hsa-miR-4635	140705329	140705335	7mer-m8	140705316	140705336	170	-25.83
CAediting_524911	chr7_5495852_-	ENSG00000090266.11	ENST00000465506	hsa-miR-589-3p	140705129	140705135	7mer-m8	140705112	140705136	154	-14.94

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_86358	chr1_109598906_+	ENSG00000090266.11	ENST00000476279	hsa-miR-197-5p	140722664	140722670	7mer-m8	140722649	140722671	145	-13.34

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NDUFB2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000464566.4	protein_coding
ENST00000462847.1	processed_transcript
ENST00000475276.1	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_609024	ENST00000464566.4	chr7_140706139_+	-241.20	-239.90	-260.20
CAediting_609025	ENST00000464566.4	chr7_140706144_+	-241.70	-239.90	-260.20
CAediting_609026	ENST00000464566.4	chr7_140706171_+	-242.80	-239.90	-260.20
CAediting_609027	ENST00000464566.4	chr7_140706185_+	-245.50	-239.90	-260.20
CAediting_609028	ENST00000464566.4	chr7_140706190_+	-241.40	-239.90	-260.20
CAediting_609029	ENST00000464566.4	chr7_140706191_+	-245.40	-239.90	-260.20
CAediting_609030	ENST00000464566.4	chr7_140706195_+	-242.80	-239.90	-260.20
CAediting_609031	ENST00000464566.4	chr7_140706261_+	-242.50	-239.90	-260.20
CAediting_609032	ENST00000464566.4	chr7_140706293_+	-239.20	-239.90	-260.20
CAediting_609033	ENST00000464566.4	chr7_140706298_+	-241.10	-239.90	-260.20
CAediting_609034	ENST00000464566.4	chr7_140706313_+	-242.60	-239.90	-260.20
CAediting_609035	ENST00000464566.4	chr7_140706337_+	-242.80	-239.90	-260.20
CAediting_609036	ENST00000464566.4	chr7_140706338_+	-242.00	-239.90	-260.20
CAediting_609037	ENST00000464566.4	chr7_140706350_+	-240.90	-239.90	-260.20
CAediting_609038	ENST00000464566.4	chr7_140706352_+	-240.20	-239.90	-260.20
CAediting_608992	ENST00000462847.1	chr7_140700201_+	-107.90	-104.00	-115.80
CAediting_608998	ENST00000462847.1	chr7_140700729_+	-108.70	-104.00	-115.80
CAediting_608999	ENST00000462847.1	chr7_140700737_+	-106.60	-104.00	-115.80
CAediting_609000	ENST00000462847.1	chr7_140700738_+	-106.30	-104.00	-115.80
CAediting_609014	ENST00000475276.1	chr7_140701856_+	-158.20	-158.00	-163.10
CAediting_609015	ENST00000475276.1	chr7_140701857_+	-158.30	-158.00	-163.10
CAediting_609016	ENST00000475276.1	chr7_140701861_+	-157.30	-158.00	-163.10
CAediting_609017	ENST00000475276.1	chr7_140701877_+	-157.20	-158.00	-163.10
CAediting_609018	ENST00000475276.1	chr7_140701881_+	-162.10	-158.00	-163.10
CAediting_609019	ENST00000475276.1	chr7_140701885_+	-158.00	-158.00	-163.10
CAediting_609020	ENST00000475276.1	chr7_140701948_+	-160.10	-158.00	-163.10
CAediting_609021	ENST00000475276.1	chr7_140701951_+	-159.90	-158.00	-163.10

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Relation with ADAR for NDUFB2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_608970	chr7_140694209_+	.	.	.	.	0.0210592495942556	0.281409418053618

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Relation with cancer stages for NDUFB2

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for NDUFB2

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for NDUFB2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
NDUFB2	O95178	DB00157	NADH	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial	SmallMoleculeDrug	approved\|nutraceutical

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RelatedDiseases for NDUFB2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene