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Editing gene: PMS2CL (CAeditome ID:441194)

Gene summary for PMS2CL

Gene summary

Gene information	Gene symbol	PMS2CL
	Gene ID	441194
	Gene name	PMS2 C-terminal like pseudogene
	Synonyms	PMS2P13
	Cytomap	7p22.1
	Type of gene	pseudo
	Description	PMS1 homolog 2, mismatch repair system component pseudogene 13postmeiotic segregation increased 2 pseudogene 13
	Modification date	20210518
	UniProtAcc	.
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for PMS2CL

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000187953.9

RNA A-to-I editing events in Cancer.

CAediting_527870(6710192, +), CAediting_527871(6725441, +), CAediting_527872(6725462, +), CAediting_527873(6726594, +), CAediting_527874(6728572, +), CAediting_527875(6728573, +), CAediting_527876(6733655, +), CAediting_527877(6734344, +), CAediting_527878(6734729, +), CAediting_527879(6734740, +), CAediting_527880(6734754, +), CAediting_527881(6734756, +), CAediting_527882(6734757, +), CAediting_527883(6734762, +), CAediting_527884(6734765, +), CAediting_527885(6734787, +), CAediting_527886(6734825, +), CAediting_527887(6734835, +), CAediting_527888(6734856, +), CAediting_527889(6734859, +), CAediting_527890(6734861, +), CAediting_527891(6734865, +), CAediting_527892(6734881, +), CAediting_527893(6734927, +), CAediting_527894(6734932, +), CAediting_527895(6734961, +), CAediting_527896(6734975, +), CAediting_527897(6734977, +), CAediting_527898(6734991, +), CAediting_527899(6735059, +), CAediting_527900(6735095, +), CAediting_527901(6735101, +), CAediting_527902(6735129, +), CAediting_527903(6735630, +), CAediting_527904(6736264, +), CAediting_527905(6736807, +), CAediting_527906(6736810, +), CAediting_527907(6736813, +), CAediting_527908(6739906, +), CAediting_527909(6740001, +), CAediting_527910(6740004, +), CAediting_527911(6740049, +), CAediting_527912(6741930, +), CAediting_527913(6742060, +), CAediting_527914(6742200, +), CAediting_527915(6743187, +), CAediting_527916(6743270, +), CAediting_527917(6744250, +), CAediting_527918(6744259, +), CAediting_527919(6744260, +), CAediting_527920(6745781, +), CAediting_527921(6745834, +), CAediting_527922(6745848, +), CAediting_527923(6751668, +), CAediting_527924(6751682, +), CAediting_527925(6751712, +), CAediting_527926(6751724, +), CAediting_527927(6751725, +), CAediting_527928(6751733, +), CAediting_527929(6751736, +), CAediting_527930(6751742, +), CAediting_527931(6751746, +), CAediting_527932(6751752, +), CAediting_527933(6751755, +), CAediting_527934(6751756, +), CAediting_527935(6751767, +), CAediting_527936(6751770, +), CAediting_527937(6751771, +), CAediting_527938(6751776, +), CAediting_527939(6751779, +), CAediting_527940(6751780, +), CAediting_527941(6751781, +), CAediting_527942(6751784, +), CAediting_527943(6751788, +), CAediting_527944(6751810, +), CAediting_527945(6751811, +), CAediting_527946(6751824, +), CAediting_527947(6751827, +), CAediting_527948(6751833, +), CAediting_527949(6751837, +), CAediting_527950(6751840, +), CAediting_527951(6751843, +), CAediting_527952(6751851, +), CAediting_527953(6751852, +), CAediting_527954(6751859, +), CAediting_527955(6751861, +), CAediting_527956(6751876, +), CAediting_527957(6751877, +), CAediting_527958(6751881, +), CAediting_527959(6751883, +), CAediting_527960(6751891, +), CAediting_527961(6751917, +), CAediting_527962(6751920, +), CAediting_527963(6751921, +), CAediting_527964(6751948, +), CAediting_527965(6752838, +), CAediting_527966(6752857, +), CAediting_527967(6752886, +), CAediting_527968(6752918, +), CAediting_527969(6752927, +), CAediting_527970(6752953, +), CAediting_527971(6752966, +), CAediting_527972(6752978, +), CAediting_527973(6753004, +), CAediting_527974(6753005, +), CAediting_527975(6753006, +), CAediting_527976(6753015, +), CAediting_527977(6753027, +),

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RNA editing positional annotations for PMS2CL using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_527870	chr7_6710192_+	ncRNA_exonic
CAediting_527871	chr7_6725441_+	ncRNA_intronic
CAediting_527872	chr7_6725462_+	ncRNA_intronic
CAediting_527873	chr7_6726594_+	ncRNA_intronic
CAediting_527874	chr7_6728572_+	ncRNA_intronic
CAediting_527875	chr7_6728573_+	ncRNA_intronic
CAediting_527876	chr7_6733655_+	ncRNA_intronic
CAediting_527877	chr7_6734344_+	ncRNA_intronic
CAediting_527878	chr7_6734729_+	ncRNA_intronic
CAediting_527879	chr7_6734740_+	ncRNA_intronic
CAediting_527880	chr7_6734754_+	ncRNA_intronic
CAediting_527881	chr7_6734756_+	ncRNA_intronic
CAediting_527882	chr7_6734757_+	ncRNA_intronic
CAediting_527883	chr7_6734762_+	ncRNA_intronic
CAediting_527884	chr7_6734765_+	ncRNA_intronic
CAediting_527885	chr7_6734787_+	ncRNA_intronic
CAediting_527886	chr7_6734825_+	ncRNA_intronic
CAediting_527887	chr7_6734835_+	ncRNA_intronic
CAediting_527888	chr7_6734856_+	ncRNA_intronic
CAediting_527889	chr7_6734859_+	ncRNA_intronic
CAediting_527890	chr7_6734861_+	ncRNA_intronic
CAediting_527891	chr7_6734865_+	ncRNA_intronic
CAediting_527892	chr7_6734881_+	ncRNA_intronic
CAediting_527893	chr7_6734927_+	ncRNA_intronic
CAediting_527894	chr7_6734932_+	ncRNA_intronic
CAediting_527895	chr7_6734961_+	ncRNA_intronic
CAediting_527896	chr7_6734975_+	ncRNA_intronic
CAediting_527897	chr7_6734977_+	ncRNA_intronic
CAediting_527898	chr7_6734991_+	ncRNA_intronic
CAediting_527899	chr7_6735059_+	ncRNA_intronic
CAediting_527900	chr7_6735095_+	ncRNA_intronic
CAediting_527901	chr7_6735101_+	ncRNA_intronic
CAediting_527902	chr7_6735129_+	ncRNA_intronic
CAediting_527903	chr7_6735630_+	ncRNA_intronic
CAediting_527904	chr7_6736264_+	ncRNA_intronic
CAediting_527905	chr7_6736807_+	ncRNA_intronic
CAediting_527906	chr7_6736810_+	ncRNA_intronic
CAediting_527907	chr7_6736813_+	ncRNA_intronic
CAediting_527908	chr7_6739906_+	ncRNA_intronic
CAediting_527909	chr7_6740001_+	ncRNA_intronic
CAediting_527910	chr7_6740004_+	ncRNA_intronic
CAediting_527911	chr7_6740049_+	ncRNA_intronic
CAediting_527912	chr7_6741930_+	ncRNA_intronic
CAediting_527913	chr7_6742060_+	ncRNA_intronic
CAediting_527914	chr7_6742200_+	ncRNA_intronic
CAediting_527915	chr7_6743187_+	ncRNA_intronic
CAediting_527916	chr7_6743270_+	ncRNA_intronic
CAediting_527917	chr7_6744250_+	ncRNA_intronic
CAediting_527918	chr7_6744259_+	ncRNA_intronic
CAediting_527919	chr7_6744260_+	ncRNA_intronic
CAediting_527920	chr7_6745781_+	ncRNA_intronic
CAediting_527921	chr7_6745834_+	ncRNA_intronic
CAediting_527922	chr7_6745848_+	ncRNA_intronic
CAediting_527923	chr7_6751668_+	ncRNA_intronic
CAediting_527924	chr7_6751682_+	ncRNA_intronic
CAediting_527925	chr7_6751712_+	ncRNA_intronic
CAediting_527926	chr7_6751724_+	ncRNA_intronic
CAediting_527927	chr7_6751725_+	ncRNA_intronic
CAediting_527928	chr7_6751733_+	ncRNA_intronic
CAediting_527929	chr7_6751736_+	ncRNA_intronic
CAediting_527930	chr7_6751742_+	ncRNA_intronic
CAediting_527931	chr7_6751746_+	ncRNA_intronic
CAediting_527932	chr7_6751752_+	ncRNA_intronic
CAediting_527933	chr7_6751755_+	ncRNA_intronic
CAediting_527934	chr7_6751756_+	ncRNA_intronic
CAediting_527935	chr7_6751767_+	ncRNA_intronic
CAediting_527936	chr7_6751770_+	ncRNA_intronic
CAediting_527937	chr7_6751771_+	ncRNA_intronic
CAediting_527938	chr7_6751776_+	ncRNA_intronic
CAediting_527939	chr7_6751779_+	ncRNA_intronic
CAediting_527940	chr7_6751780_+	ncRNA_intronic
CAediting_527941	chr7_6751781_+	ncRNA_intronic
CAediting_527942	chr7_6751784_+	ncRNA_intronic
CAediting_527943	chr7_6751788_+	ncRNA_intronic
CAediting_527944	chr7_6751810_+	ncRNA_intronic
CAediting_527945	chr7_6751811_+	ncRNA_intronic
CAediting_527946	chr7_6751824_+	ncRNA_intronic
CAediting_527947	chr7_6751827_+	ncRNA_intronic
CAediting_527948	chr7_6751833_+	ncRNA_intronic
CAediting_527949	chr7_6751837_+	ncRNA_intronic
CAediting_527950	chr7_6751840_+	ncRNA_intronic
CAediting_527951	chr7_6751843_+	ncRNA_intronic
CAediting_527952	chr7_6751851_+	ncRNA_intronic
CAediting_527953	chr7_6751852_+	ncRNA_intronic
CAediting_527954	chr7_6751859_+	ncRNA_intronic
CAediting_527955	chr7_6751861_+	ncRNA_intronic
CAediting_527956	chr7_6751876_+	ncRNA_intronic
CAediting_527957	chr7_6751877_+	ncRNA_intronic
CAediting_527958	chr7_6751881_+	ncRNA_intronic
CAediting_527959	chr7_6751883_+	ncRNA_intronic
CAediting_527960	chr7_6751891_+	ncRNA_intronic
CAediting_527961	chr7_6751917_+	ncRNA_intronic
CAediting_527962	chr7_6751920_+	ncRNA_intronic
CAediting_527963	chr7_6751921_+	ncRNA_intronic
CAediting_527964	chr7_6751948_+	ncRNA_intronic
CAediting_527965	chr7_6752838_+	ncRNA_intronic
CAediting_527966	chr7_6752857_+	ncRNA_intronic
CAediting_527967	chr7_6752886_+	ncRNA_intronic
CAediting_527968	chr7_6752918_+	ncRNA_intronic
CAediting_527969	chr7_6752927_+	ncRNA_intronic
CAediting_527970	chr7_6752953_+	ncRNA_intronic
CAediting_527971	chr7_6752966_+	ncRNA_intronic
CAediting_527972	chr7_6752978_+	ncRNA_intronic
CAediting_527973	chr7_6753004_+	ncRNA_intronic
CAediting_527974	chr7_6753005_+	ncRNA_intronic
CAediting_527975	chr7_6753006_+	ncRNA_intronic
CAediting_527976	chr7_6753015_+	ncRNA_intronic
CAediting_527977	chr7_6753027_+	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_527870	chr7_6710192_+	SINE	Alu	AluSg
CAediting_527871	chr7_6725441_+	SINE	Alu	AluSz6
CAediting_527872	chr7_6725462_+	SINE	Alu	AluSz6
CAediting_527873	chr7_6726594_+	SINE	Alu	AluSz6
CAediting_527874	chr7_6728572_+	SINE	Alu	AluJr
CAediting_527875	chr7_6728573_+	SINE	Alu	AluJr
CAediting_527876	chr7_6733655_+	SINE	Alu	AluJb
CAediting_527877	chr7_6734344_+	SINE	Alu	AluY
CAediting_527879	chr7_6734740_+	SINE	Alu	AluSq2
CAediting_527880	chr7_6734754_+	SINE	Alu	AluSq2
CAediting_527881	chr7_6734756_+	SINE	Alu	AluSq2
CAediting_527882	chr7_6734757_+	SINE	Alu	AluSq2
CAediting_527883	chr7_6734762_+	SINE	Alu	AluSq2
CAediting_527884	chr7_6734765_+	SINE	Alu	AluSq2
CAediting_527885	chr7_6734787_+	SINE	Alu	AluSq2
CAediting_527886	chr7_6734825_+	SINE	Alu	AluSq2
CAediting_527887	chr7_6734835_+	SINE	Alu	AluSq2
CAediting_527888	chr7_6734856_+	SINE	Alu	AluSq2
CAediting_527889	chr7_6734859_+	SINE	Alu	AluSq2
CAediting_527890	chr7_6734861_+	SINE	Alu	AluSq2
CAediting_527891	chr7_6734865_+	SINE	Alu	AluSq2
CAediting_527892	chr7_6734881_+	SINE	Alu	AluSq2
CAediting_527893	chr7_6734927_+	SINE	Alu	AluSq2
CAediting_527894	chr7_6734932_+	SINE	Alu	AluSq2
CAediting_527895	chr7_6734961_+	SINE	Alu	AluSq2
CAediting_527896	chr7_6734975_+	SINE	Alu	AluSq2
CAediting_527897	chr7_6734977_+	SINE	Alu	AluSq2
CAediting_527898	chr7_6734991_+	SINE	Alu	AluSq2
CAediting_527899	chr7_6735059_+	SINE	Alu	AluJb
CAediting_527900	chr7_6735095_+	SINE	Alu	AluJb
CAediting_527901	chr7_6735101_+	SINE	Alu	AluJb
CAediting_527902	chr7_6735129_+	SINE	Alu	AluJb
CAediting_527903	chr7_6735630_+	SINE	Alu	AluY
CAediting_527904	chr7_6736264_+	SINE	Alu	AluSx3
CAediting_527905	chr7_6736807_+	SINE	Alu	AluSz6
CAediting_527906	chr7_6736810_+	SINE	Alu	AluSz6
CAediting_527907	chr7_6736813_+	SINE	Alu	AluSz6
CAediting_527908	chr7_6739906_+	SINE	Alu	AluSx1
CAediting_527909	chr7_6740001_+	SINE	Alu	AluSx1
CAediting_527910	chr7_6740004_+	SINE	Alu	AluSx1
CAediting_527911	chr7_6740049_+	SINE	Alu	AluSx1
CAediting_527912	chr7_6741930_+	SINE	Alu	AluJr
CAediting_527913	chr7_6742060_+	SINE	Alu	AluSx
CAediting_527914	chr7_6742200_+	SINE	Alu	AluSq2
CAediting_527915	chr7_6743187_+	SINE	Alu	AluJb
CAediting_527916	chr7_6743270_+	SINE	Alu	AluJb
CAediting_527917	chr7_6744250_+	SINE	Alu	AluSx1
CAediting_527918	chr7_6744259_+	SINE	Alu	AluSx1
CAediting_527919	chr7_6744260_+	SINE	Alu	AluSx1
CAediting_527920	chr7_6745781_+	SINE	Alu	AluSz6
CAediting_527921	chr7_6745834_+	SINE	Alu	AluSz6
CAediting_527922	chr7_6745848_+	SINE	Alu	AluSz6
CAediting_527923	chr7_6751668_+	SINE	Alu	AluSx
CAediting_527924	chr7_6751682_+	SINE	Alu	AluSx
CAediting_527925	chr7_6751712_+	SINE	Alu	AluSx
CAediting_527926	chr7_6751724_+	SINE	Alu	AluSx
CAediting_527927	chr7_6751725_+	SINE	Alu	AluSx
CAediting_527928	chr7_6751733_+	SINE	Alu	AluSx
CAediting_527929	chr7_6751736_+	SINE	Alu	AluSx
CAediting_527930	chr7_6751742_+	SINE	Alu	AluSx
CAediting_527931	chr7_6751746_+	SINE	Alu	AluSx
CAediting_527932	chr7_6751752_+	SINE	Alu	AluSx
CAediting_527933	chr7_6751755_+	SINE	Alu	AluSx
CAediting_527934	chr7_6751756_+	SINE	Alu	AluSx
CAediting_527935	chr7_6751767_+	SINE	Alu	AluSx
CAediting_527936	chr7_6751770_+	SINE	Alu	AluSx
CAediting_527937	chr7_6751771_+	SINE	Alu	AluSx
CAediting_527938	chr7_6751776_+	SINE	Alu	AluSx
CAediting_527939	chr7_6751779_+	SINE	Alu	AluSx
CAediting_527940	chr7_6751780_+	SINE	Alu	AluSx
CAediting_527941	chr7_6751781_+	SINE	Alu	AluSx
CAediting_527942	chr7_6751784_+	SINE	Alu	AluSx
CAediting_527943	chr7_6751788_+	SINE	Alu	AluSx
CAediting_527944	chr7_6751810_+	SINE	Alu	AluSx
CAediting_527945	chr7_6751811_+	SINE	Alu	AluSx
CAediting_527946	chr7_6751824_+	SINE	Alu	AluSx
CAediting_527947	chr7_6751827_+	SINE	Alu	AluSx
CAediting_527948	chr7_6751833_+	SINE	Alu	AluSx
CAediting_527949	chr7_6751837_+	SINE	Alu	AluSx
CAediting_527950	chr7_6751840_+	SINE	Alu	AluSx
CAediting_527951	chr7_6751843_+	SINE	Alu	AluSx
CAediting_527952	chr7_6751851_+	SINE	Alu	AluSx
CAediting_527953	chr7_6751852_+	SINE	Alu	AluSx
CAediting_527954	chr7_6751859_+	SINE	Alu	AluSx
CAediting_527955	chr7_6751861_+	SINE	Alu	AluSx
CAediting_527956	chr7_6751876_+	SINE	Alu	AluSx
CAediting_527957	chr7_6751877_+	SINE	Alu	AluSx
CAediting_527958	chr7_6751881_+	SINE	Alu	AluSx
CAediting_527959	chr7_6751883_+	SINE	Alu	AluSx
CAediting_527960	chr7_6751891_+	SINE	Alu	AluSx
CAediting_527961	chr7_6751917_+	SINE	Alu	AluSx
CAediting_527962	chr7_6751920_+	SINE	Alu	AluSx
CAediting_527963	chr7_6751921_+	SINE	Alu	AluSx
CAediting_527964	chr7_6751948_+	Simple_repeat	Simple_repeat	(AAAAC)n
CAediting_527965	chr7_6752838_+	SINE	Alu	AluSq2
CAediting_527966	chr7_6752857_+	SINE	Alu	AluSq2
CAediting_527967	chr7_6752886_+	SINE	Alu	AluSq2
CAediting_527968	chr7_6752918_+	SINE	Alu	AluSq2
CAediting_527969	chr7_6752927_+	SINE	Alu	AluSq2
CAediting_527970	chr7_6752953_+	SINE	Alu	AluSq2
CAediting_527971	chr7_6752966_+	SINE	Alu	AluSq2
CAediting_527972	chr7_6752978_+	SINE	Alu	AluSq2
CAediting_527973	chr7_6753004_+	SINE	Alu	AluSq2
CAediting_527974	chr7_6753005_+	SINE	Alu	AluSq2
CAediting_527975	chr7_6753006_+	SINE	Alu	AluSq2
CAediting_527976	chr7_6753015_+	SINE	Alu	AluSq2
CAediting_527977	chr7_6753027_+	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for PMS2CL

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000187953.9.PMS2CL.

Correlation between RNA A-to-I editing and PSI for ENSG00000187953.9.PMS2CL.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PMS2CL

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LUAD.CAediting_527949.ENSG00000187953.PMS2CL.png
Soverview

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Protein coding region RNA A-to-I editings for PMS2CL

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for PMS2CL

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PMS2CL

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000486256.4	processed_transcript

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_527870	ENST00000486256.4	chr7_6710192_+	-1076.90	-1073.10	-1076.00
CAediting_527977	ENST00000486256.4	chr7_6753027_+	-1074.00	-1073.10	-1076.00

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Relation with ADAR for PMS2CL

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_527949	chr7_6751837_+	0.000973814660275169	0.144493071236167	.	.	.	.
PRAD	CAediting_527949	chr7_6751837_+	0.0330028675765068	0.172486372748752	.	.	.	.
THCA	CAediting_527949	chr7_6751837_+	0.0126835827042586	0.230791921662825	.	.	.	.
KIRC	CAediting_527949	chr7_6751837_+	0.0252827857131515	0.166271701489632	.	.	.	.
KIRP	CAediting_527949	chr7_6751837_+	0.0120060426808132	0.20670553209597	.	.	.	.
BRCA	CAediting_527957	chr7_6751877_+	2.37157530839179e-05	0.337736807322767	.	.	.	.
GBM	CAediting_527957	chr7_6751877_+	0.00941362236714501	0.228707257109543	.	.	.	.
BRCA	CAediting_527960	chr7_6751891_+	0.00388449003053003	0.303112789128865	.	.	.	.
BRCA	CAediting_527974	chr7_6753005_+	0.00917519224357258	0.323258491258647	.	.	.	.
BRCA	CAediting_527975	chr7_6753006_+	0.00431383830682663	0.217882313605963	.	.	.	.
LUSC	CAediting_527975	chr7_6753006_+	0.00880114565881473	0.315378418956843	.	.	.	.
SKCM	CAediting_527975	chr7_6753006_+	0.0305950261016561	0.203540808332163	.	.	.	.

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Relation with cancer stages for PMS2CL

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ESCA	clinical_stage	CAediting_527949	chr7_6751837_+	0.0415670085683366	-0.29532362943852
KIRC	pathologic_stage	CAediting_527949	chr7_6751837_+	0.0033285838198057	0.217100032303033

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Relation with survival for PMS2CL

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
BRCA	CAediting_527962	chr7_6751920_+	0.0460631411566427	0.0457504	1.39297e-07
OV	CAediting_527946	chr7_6751824_+	0.0254865054831728	0.0333678	17.5231

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RelatedDrugs for PMS2CL

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for PMS2CL

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene