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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: KMT2A (CAeditome ID:4297)

Gene summary for KMT2A

check button Gene summary
Gene informationGene symbol

KMT2A

Gene ID

4297

Gene namelysine methyltransferase 2A
SynonymsALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTS
Cytomap

11q23.3

Type of geneprotein-coding
Descriptionhistone-lysine N-methyltransferase 2ACXXC-type zinc finger protein 7lysine (K)-specific methyltransferase 2Alysine N-methyltransferase 2Amixed lineage leukemia 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)trithorax-like
Modification date20210531
UniProtAcc

Q03164

Context- 33298164(KMT2A/C mutations function as a potential predictive biomarker for immunotherapy in solid tumors)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
KMT2A

GO:0008270

Histone-lysine N-methyltransferase 2A

16990798

KMT2A

GO:0008270

Histone-lysine N-methyltransferase 2A

19187761

KMT2A

GO:0008270

Histone-lysine N-methyltransferase 2A

29276034

KMT2A

GO:0042800

Histone-lysine N-methyltransferase 2A

19187761

KMT2A

GO:0042800

Histone-lysine N-methyltransferase 2A

19556245

KMT2A

GO:0042800

Histone-lysine N-methyltransferase 2A

24235145

KMT2A

GO:0042803

Histone-lysine N-methyltransferase 2A

11313484

KMT2A

GO:0045322

Histone-lysine N-methyltransferase 2A

16990798

KMT2A

GO:0045322

Histone-lysine N-methyltransferase 2A

20010842

KMT2A

GO:0045322

Histone-lysine N-methyltransferase 2A

29276034

KMT2A

GO:0070577

Histone-lysine N-methyltransferase 2A

19187761

KMT2A

GO:0106363

Histone-lysine N-methyltransferase 2A

24235145

KMT2A

GO:0044648

Histone-lysine N-methyltransferase 2A

25561738

KMT2A

GO:0045944

Histone-lysine N-methyltransferase 2A

20861184

KMT2A

GO:0051568

Histone-lysine N-methyltransferase 2A

19556245

KMT2A

GO:0065003

Histone-lysine N-methyltransferase 2A

15199122

KMT2A

GO:0080182

Histone-lysine N-methyltransferase 2A

20861184

KMT2A

GO:0097692

Histone-lysine N-methyltransferase 2A

25561738

KMT2A

GO:0097692

Histone-lysine N-methyltransferase 2A

26324722

KMT2A

GO:0005634

Histone-lysine N-methyltransferase 2A

11313484

KMT2A

GO:0005634

Histone-lysine N-methyltransferase 2A

15640349

KMT2A

GO:0005654

Histone-lysine N-methyltransferase 2A

0000052

KMT2A

GO:0005829

Histone-lysine N-methyltransferase 2A

0000052

KMT2A

GO:0005634

Histone-lysine N-methyltransferase 2A

22046413

KMT2A

GO:0035097

Histone-lysine N-methyltransferase 2A

19556245

KMT2A

GO:0071339

Histone-lysine N-methyltransferase 2A

15960975


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RNA A-to-I events for KMT2A

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000118058.19

check button RNA A-to-I editing events in Cancer.
CAediting_854675(118441246, +), CAediting_854676(118444659, +), CAediting_854677(118444666, +), CAediting_854678(118444673, +), CAediting_854679(118444674, +), CAediting_854680(118444677, +), CAediting_854681(118444691, +), CAediting_854682(118444700, +), CAediting_854683(118444703, +), CAediting_854684(118444710, +), CAediting_854685(118444713, +), CAediting_854686(118444735, +), CAediting_854687(118444740, +), CAediting_854688(118444757, +), CAediting_854689(118444810, +), CAediting_854690(118444822, +), CAediting_854691(118444827, +), CAediting_854692(118444849, +), CAediting_854693(118445769, +), CAediting_854694(118445770, +), CAediting_854695(118445778, +), CAediting_854696(118445929, +), CAediting_854697(118445948, +), CAediting_854698(118445967, +), CAediting_854699(118446014, +), CAediting_854700(118446026, +), CAediting_854701(118446085, +), CAediting_854702(118446093, +), CAediting_854703(118446100, +), CAediting_854704(118446116, +), CAediting_854705(118446120, +), CAediting_854706(118446124, +), CAediting_854707(118446139, +), CAediting_854708(118446150, +), CAediting_854709(118446153, +), CAediting_854710(118446184, +), CAediting_854711(118446198, +), CAediting_854712(118446199, +), CAediting_854713(118446202, +), CAediting_854714(118446206, +), CAediting_854715(118446208, +), CAediting_854716(118446222, +), CAediting_854717(118446228, +), CAediting_854718(118446234, +), CAediting_854719(118446238, +), CAediting_854720(118446260, +), CAediting_854721(118446269, +), CAediting_854722(118446270, +), CAediting_854723(118446281, +), CAediting_854724(118446331, +), CAediting_854725(118446358, +), CAediting_854726(118449284, +), CAediting_854727(118449286, +), CAediting_854728(118449296, +), CAediting_854729(118449305, +), CAediting_854730(118449311, +), CAediting_854731(118449319, +), CAediting_854732(118449332, +), CAediting_854733(118449342, +), CAediting_854734(118449343, +), CAediting_854735(118449357, +), CAediting_854736(118449379, +), CAediting_854737(118449409, +), CAediting_854738(118449441, +), CAediting_854739(118449442, +), CAediting_854740(118449465, +), CAediting_854741(118449471, +), CAediting_854742(118449475, +), CAediting_854743(118449479, +), CAediting_854744(118449482, +), CAediting_854745(118449483, +), CAediting_854746(118449511, +), CAediting_854747(118449531, +), CAediting_854748(118449538, +), CAediting_854749(118449551, +), CAediting_854750(118449566, +), CAediting_854751(118449568, +), CAediting_854752(118449605, +), CAediting_854753(118451311, +), CAediting_854754(118451312, +), CAediting_854755(118451329, +), CAediting_854756(118452272, +), CAediting_854757(118452353, +), CAediting_854758(118452403, +), CAediting_854759(118452411, +), CAediting_854760(118452425, +), CAediting_854761(118452447, +), CAediting_854762(118452451, +), CAediting_854763(118452452, +), CAediting_854764(118452516, +), CAediting_854765(118452517, +), CAediting_854766(118452519, +), CAediting_854767(118452836, +), CAediting_854768(118452894, +), CAediting_854769(118455143, +), CAediting_854770(118455159, +), CAediting_854771(118456098, +), CAediting_854772(118456104, +), CAediting_854773(118456119, +), CAediting_854774(118456226, +), CAediting_854775(118456235, +), CAediting_854776(118456236, +), CAediting_854777(118456238, +), CAediting_854778(118456245, +), CAediting_854779(118456540, +), CAediting_854780(118458107, +), CAediting_854781(118458115, +), CAediting_854782(118458153, +), CAediting_854783(118458163, +), CAediting_854784(118458184, +), CAediting_854785(118458196, +), CAediting_854786(118458323, +), CAediting_854787(118458324, +), CAediting_854788(118458355, +), CAediting_854789(118459094, +), CAediting_854790(118459150, +), CAediting_854791(118459195, +), CAediting_854792(118459209, +), CAediting_854793(118459719, +), CAediting_854794(118459820, +), CAediting_854795(118460312, +), CAediting_854796(118460344, +), CAediting_854797(118460350, +), CAediting_854798(118460524, +), CAediting_854799(118460525, +), CAediting_854800(118460528, +), CAediting_854801(118460533, +), CAediting_854802(118464350, +), CAediting_854803(118464401, +), CAediting_854804(118464461, +), CAediting_854805(118464488, +), CAediting_854806(118464489, +), CAediting_854807(118465144, +), CAediting_854808(118465159, +), CAediting_854809(118465168, +), CAediting_854810(118465183, +), CAediting_854811(118465187, +), CAediting_854812(118465188, +), CAediting_854813(118466371, +), CAediting_854814(118466684, +), CAediting_854815(118466694, +), CAediting_854816(118466695, +), CAediting_854817(118466721, +), CAediting_854818(118466727, +), CAediting_854819(118466781, +), CAediting_854820(118466787, +), CAediting_854821(118466922, +), CAediting_854822(118467152, +), CAediting_854823(118475688, +), CAediting_854824(118476460, +), CAediting_854825(118476464, +), CAediting_854826(118476467, +), CAediting_854827(118483278, +), CAediting_854828(118497187, +), CAediting_854829(118497189, +),

Top

RNA editing positional annotations for KMT2A using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_854675chr11_118441246_+intronic
CAediting_854676chr11_118444659_+intronic
CAediting_854677chr11_118444666_+intronic
CAediting_854678chr11_118444673_+intronic
CAediting_854679chr11_118444674_+intronic
CAediting_854680chr11_118444677_+intronic
CAediting_854681chr11_118444691_+intronic
CAediting_854682chr11_118444700_+intronic
CAediting_854683chr11_118444703_+intronic
CAediting_854684chr11_118444710_+intronic
CAediting_854685chr11_118444713_+intronic
CAediting_854686chr11_118444735_+intronic
CAediting_854687chr11_118444740_+intronic
CAediting_854688chr11_118444757_+intronic
CAediting_854689chr11_118444810_+intronic
CAediting_854690chr11_118444822_+intronic
CAediting_854691chr11_118444827_+intronic
CAediting_854692chr11_118444849_+intronic
CAediting_854693chr11_118445769_+intronic
CAediting_854694chr11_118445770_+intronic
CAediting_854695chr11_118445778_+intronic
CAediting_854696chr11_118445929_+intronic
CAediting_854697chr11_118445948_+intronic
CAediting_854698chr11_118445967_+intronic
CAediting_854699chr11_118446014_+intronic
CAediting_854700chr11_118446026_+intronic
CAediting_854701chr11_118446085_+intronic
CAediting_854702chr11_118446093_+intronic
CAediting_854703chr11_118446100_+intronic
CAediting_854704chr11_118446116_+intronic
CAediting_854705chr11_118446120_+intronic
CAediting_854706chr11_118446124_+intronic
CAediting_854707chr11_118446139_+intronic
CAediting_854708chr11_118446150_+intronic
CAediting_854709chr11_118446153_+intronic
CAediting_854710chr11_118446184_+intronic
CAediting_854711chr11_118446198_+intronic
CAediting_854712chr11_118446199_+intronic
CAediting_854713chr11_118446202_+intronic
CAediting_854714chr11_118446206_+intronic
CAediting_854715chr11_118446208_+intronic
CAediting_854716chr11_118446222_+intronic
CAediting_854717chr11_118446228_+intronic
CAediting_854718chr11_118446234_+intronic
CAediting_854719chr11_118446238_+intronic
CAediting_854720chr11_118446260_+intronic
CAediting_854721chr11_118446269_+intronic
CAediting_854722chr11_118446270_+intronic
CAediting_854723chr11_118446281_+intronic
CAediting_854724chr11_118446331_+intronic
CAediting_854725chr11_118446358_+intronic
CAediting_854726chr11_118449284_+UTR3
CAediting_854727chr11_118449286_+UTR3
CAediting_854728chr11_118449296_+UTR3
CAediting_854729chr11_118449305_+UTR3
CAediting_854730chr11_118449311_+UTR3
CAediting_854731chr11_118449319_+UTR3
CAediting_854732chr11_118449332_+UTR3
CAediting_854733chr11_118449342_+UTR3
CAediting_854734chr11_118449343_+UTR3
CAediting_854735chr11_118449357_+UTR3
CAediting_854736chr11_118449379_+UTR3
CAediting_854737chr11_118449409_+UTR3
CAediting_854738chr11_118449441_+UTR3
CAediting_854739chr11_118449442_+UTR3
CAediting_854740chr11_118449465_+UTR3
CAediting_854741chr11_118449471_+UTR3
CAediting_854742chr11_118449475_+UTR3
CAediting_854743chr11_118449479_+UTR3
CAediting_854744chr11_118449482_+UTR3
CAediting_854745chr11_118449483_+UTR3
CAediting_854746chr11_118449511_+UTR3
CAediting_854747chr11_118449531_+UTR3
CAediting_854748chr11_118449538_+UTR3
CAediting_854749chr11_118449551_+UTR3
CAediting_854750chr11_118449566_+UTR3
CAediting_854751chr11_118449568_+UTR3
CAediting_854752chr11_118449605_+UTR3
CAediting_854753chr11_118451311_+intronic
CAediting_854754chr11_118451312_+intronic
CAediting_854755chr11_118451329_+intronic
CAediting_854756chr11_118452272_+intronic
CAediting_854757chr11_118452353_+intronic
CAediting_854758chr11_118452403_+intronic
CAediting_854759chr11_118452411_+intronic
CAediting_854760chr11_118452425_+intronic
CAediting_854761chr11_118452447_+intronic
CAediting_854762chr11_118452451_+intronic
CAediting_854763chr11_118452452_+intronic
CAediting_854764chr11_118452516_+intronic
CAediting_854765chr11_118452517_+intronic
CAediting_854766chr11_118452519_+intronic
CAediting_854767chr11_118452836_+intronic
CAediting_854768chr11_118452894_+intronic
CAediting_854769chr11_118455143_+intronic
CAediting_854770chr11_118455159_+intronic
CAediting_854771chr11_118456098_+intronic
CAediting_854772chr11_118456104_+intronic
CAediting_854773chr11_118456119_+intronic
CAediting_854774chr11_118456226_+intronic
CAediting_854775chr11_118456235_+intronic
CAediting_854776chr11_118456236_+intronic
CAediting_854777chr11_118456238_+intronic
CAediting_854778chr11_118456245_+intronic
CAediting_854779chr11_118456540_+intronic
CAediting_854780chr11_118458107_+intronic
CAediting_854781chr11_118458115_+intronic
CAediting_854782chr11_118458153_+intronic
CAediting_854783chr11_118458163_+intronic
CAediting_854784chr11_118458184_+intronic
CAediting_854785chr11_118458196_+intronic
CAediting_854786chr11_118458323_+intronic
CAediting_854787chr11_118458324_+intronic
CAediting_854788chr11_118458355_+intronic
CAediting_854789chr11_118459094_+intronic
CAediting_854790chr11_118459150_+intronic
CAediting_854791chr11_118459195_+intronic
CAediting_854792chr11_118459209_+intronic
CAediting_854793chr11_118459719_+intronic
CAediting_854794chr11_118459820_+intronic
CAediting_854795chr11_118460312_+intronic
CAediting_854796chr11_118460344_+intronic
CAediting_854797chr11_118460350_+intronic
CAediting_854798chr11_118460524_+intronic
CAediting_854799chr11_118460525_+intronic
CAediting_854800chr11_118460528_+intronic
CAediting_854801chr11_118460533_+intronic
CAediting_854802chr11_118464350_+intronic
CAediting_854803chr11_118464401_+intronic
CAediting_854804chr11_118464461_+intronic
CAediting_854805chr11_118464488_+intronic
CAediting_854806chr11_118464489_+intronic
CAediting_854807chr11_118465144_+intronic
CAediting_854808chr11_118465159_+intronic
CAediting_854809chr11_118465168_+intronic
CAediting_854810chr11_118465183_+intronic
CAediting_854811chr11_118465187_+intronic
CAediting_854812chr11_118465188_+intronic
CAediting_854813chr11_118466371_+intronic
CAediting_854814chr11_118466684_+intronic
CAediting_854815chr11_118466694_+intronic
CAediting_854816chr11_118466695_+intronic
CAediting_854817chr11_118466721_+intronic
CAediting_854818chr11_118466727_+intronic
CAediting_854819chr11_118466781_+intronic
CAediting_854820chr11_118466787_+intronic
CAediting_854821chr11_118466922_+intronic
CAediting_854822chr11_118467152_+intronic
CAediting_854823chr11_118475688_+intronic
CAediting_854824chr11_118476460_+intronic
CAediting_854825chr11_118476464_+intronic
CAediting_854826chr11_118476467_+intronic
CAediting_854827chr11_118483278_+ncRNA_intronic
CAediting_854828chr11_118497187_+intronic
CAediting_854829chr11_118497189_+intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_854675chr11_118441246_+SINEAluFLAM_A
CAediting_854676chr11_118444659_+SINEAluAluJb
CAediting_854677chr11_118444666_+SINEAluAluJb
CAediting_854678chr11_118444673_+SINEAluAluJb
CAediting_854679chr11_118444674_+SINEAluAluJb
CAediting_854680chr11_118444677_+SINEAluAluJb
CAediting_854681chr11_118444691_+SINEAluAluJb
CAediting_854682chr11_118444700_+SINEAluAluJb
CAediting_854683chr11_118444703_+SINEAluAluJb
CAediting_854684chr11_118444710_+SINEAluAluJb
CAediting_854685chr11_118444713_+SINEAluAluJb
CAediting_854686chr11_118444735_+SINEAluAluJb
CAediting_854687chr11_118444740_+SINEAluAluJb
CAediting_854688chr11_118444757_+SINEAluAluJb
CAediting_854689chr11_118444810_+SINEAluAluJb
CAediting_854690chr11_118444822_+SINEAluAluJb
CAediting_854691chr11_118444827_+SINEAluAluJb
CAediting_854692chr11_118444849_+SINEAluAluJb
CAediting_854693chr11_118445769_+SINEAluAluSx
CAediting_854694chr11_118445770_+SINEAluAluSx
CAediting_854695chr11_118445778_+SINEAluAluSx
CAediting_854696chr11_118445929_+SINEAluAluSx
CAediting_854697chr11_118445948_+SINEAluAluSx
CAediting_854698chr11_118445967_+SINEAluAluSx
CAediting_854699chr11_118446014_+SINEAluAluSx
CAediting_854700chr11_118446026_+SINEAluAluSx
CAediting_854701chr11_118446085_+SINEAluAluSz
CAediting_854702chr11_118446093_+SINEAluAluSz
CAediting_854703chr11_118446100_+SINEAluAluSz
CAediting_854704chr11_118446116_+SINEAluAluSz
CAediting_854705chr11_118446120_+SINEAluAluSz
CAediting_854706chr11_118446124_+SINEAluAluSz
CAediting_854707chr11_118446139_+SINEAluAluSz
CAediting_854708chr11_118446150_+SINEAluAluSz
CAediting_854709chr11_118446153_+SINEAluAluSz
CAediting_854710chr11_118446184_+SINEAluAluSz
CAediting_854711chr11_118446198_+SINEAluAluSz
CAediting_854712chr11_118446199_+SINEAluAluSz
CAediting_854713chr11_118446202_+SINEAluAluSz
CAediting_854714chr11_118446206_+SINEAluAluSz
CAediting_854715chr11_118446208_+SINEAluAluSz
CAediting_854716chr11_118446222_+SINEAluAluSz
CAediting_854717chr11_118446228_+SINEAluAluSz
CAediting_854718chr11_118446234_+SINEAluAluSz
CAediting_854719chr11_118446238_+SINEAluAluSz
CAediting_854720chr11_118446260_+SINEAluAluSz
CAediting_854721chr11_118446269_+SINEAluAluSz
CAediting_854722chr11_118446270_+SINEAluAluSz
CAediting_854723chr11_118446281_+SINEAluAluSz
CAediting_854724chr11_118446331_+SINEAluAluSz
CAediting_854725chr11_118446358_+Simple_repeatSimple_repeat(AAAAG)n
CAediting_854726chr11_118449284_+SINEAluAluJr
CAediting_854727chr11_118449286_+SINEAluAluJr
CAediting_854728chr11_118449296_+SINEAluAluJr
CAediting_854729chr11_118449305_+SINEAluAluJr
CAediting_854730chr11_118449311_+SINEAluAluJr
CAediting_854731chr11_118449319_+SINEAluAluJr
CAediting_854732chr11_118449332_+SINEAluAluJr
CAediting_854733chr11_118449342_+SINEAluAluJr
CAediting_854734chr11_118449343_+SINEAluAluJr
CAediting_854735chr11_118449357_+SINEAluAluJr
CAediting_854736chr11_118449379_+SINEAluAluJr
CAediting_854737chr11_118449409_+SINEAluAluJr
CAediting_854738chr11_118449441_+SINEAluAluJr
CAediting_854739chr11_118449442_+SINEAluAluJr
CAediting_854740chr11_118449465_+SINEAluAluJr
CAediting_854741chr11_118449471_+SINEAluAluJr
CAediting_854742chr11_118449475_+SINEAluAluJr
CAediting_854743chr11_118449479_+SINEAluAluJr
CAediting_854744chr11_118449482_+SINEAluAluJr
CAediting_854745chr11_118449483_+SINEAluAluJr
CAediting_854746chr11_118449511_+SINEAluAluJr
CAediting_854747chr11_118449531_+SINEAluAluJr
CAediting_854748chr11_118449538_+SINEAluAluJr
CAediting_854749chr11_118449551_+SINEAluAluJr
CAediting_854750chr11_118449566_+SINEAluAluJr
CAediting_854751chr11_118449568_+SINEAluAluJr
CAediting_854752chr11_118449605_+SINEAluAluJr
CAediting_854753chr11_118451311_+SINEAluAluJo
CAediting_854754chr11_118451312_+SINEAluAluJo
CAediting_854755chr11_118451329_+SINEAluAluJo
CAediting_854756chr11_118452272_+SINEAluAluJr
CAediting_854757chr11_118452353_+SINEAluAluJr
CAediting_854758chr11_118452403_+SINEAluAluJr
CAediting_854759chr11_118452411_+SINEAluAluJr
CAediting_854760chr11_118452425_+SINEAluAluJr
CAediting_854761chr11_118452447_+SINEAluAluJr
CAediting_854762chr11_118452451_+SINEAluAluJr
CAediting_854763chr11_118452452_+SINEAluAluJr
CAediting_854764chr11_118452516_+SINEAluAluJr
CAediting_854765chr11_118452517_+SINEAluAluJr
CAediting_854766chr11_118452519_+SINEAluAluJr
CAediting_854767chr11_118452836_+SINEAluAluSx4
CAediting_854768chr11_118452894_+SINEAluAluSx4
CAediting_854769chr11_118455143_+SINEAluAluJo
CAediting_854770chr11_118455159_+SINEAluAluJo
CAediting_854771chr11_118456098_+SINEAluFLAM_C
CAediting_854772chr11_118456104_+SINEAluFLAM_C
CAediting_854773chr11_118456119_+SINEAluFLAM_C
CAediting_854774chr11_118456226_+SINEAluAluJr4
CAediting_854775chr11_118456235_+SINEAluAluJr4
CAediting_854776chr11_118456236_+SINEAluAluJr4
CAediting_854777chr11_118456238_+SINEAluAluJr4
CAediting_854778chr11_118456245_+SINEAluAluJr4
CAediting_854779chr11_118456540_+SINEAluAluSx3
CAediting_854780chr11_118458107_+SINEAluAluJo
CAediting_854781chr11_118458115_+SINEAluAluJo
CAediting_854782chr11_118458153_+SINEAluAluJo
CAediting_854783chr11_118458163_+SINEAluAluJo
CAediting_854784chr11_118458184_+SINEAluAluJo
CAediting_854785chr11_118458196_+SINEAluAluJo
CAediting_854786chr11_118458323_+SINEAluAluJo
CAediting_854787chr11_118458324_+SINEAluAluJo
CAediting_854788chr11_118458355_+SINEAluAluJo
CAediting_854789chr11_118459094_+SINEAluAluSz6
CAediting_854790chr11_118459150_+SINEAluAluSz6
CAediting_854791chr11_118459195_+SINEAluAluSz6
CAediting_854792chr11_118459209_+SINEAluAluSz6
CAediting_854793chr11_118459719_+SINEAluAluSz
CAediting_854794chr11_118459820_+SINEAluAluSz
CAediting_854795chr11_118460312_+SINEAluAluJb
CAediting_854796chr11_118460344_+SINEAluAluJb
CAediting_854797chr11_118460350_+SINEAluAluJb
CAediting_854798chr11_118460524_+SINEAluAluJb
CAediting_854799chr11_118460525_+SINEAluAluJb
CAediting_854800chr11_118460528_+SINEAluAluJb
CAediting_854801chr11_118460533_+SINEAluAluJb
CAediting_854802chr11_118464350_+SINEAluAluSq2
CAediting_854803chr11_118464401_+SINEAluAluSq2
CAediting_854804chr11_118464461_+SINEAluAluSq2
CAediting_854805chr11_118464488_+SINEAluAluSq2
CAediting_854806chr11_118464489_+SINEAluAluSq2
CAediting_854807chr11_118465144_+SINEAluAluSc
CAediting_854808chr11_118465159_+SINEAluAluSc
CAediting_854809chr11_118465168_+SINEAluAluSc
CAediting_854810chr11_118465183_+SINEAluAluSc
CAediting_854811chr11_118465187_+SINEAluAluSc
CAediting_854812chr11_118465188_+SINEAluAluSc
CAediting_854813chr11_118466371_+SINEAluAluJr4
CAediting_854814chr11_118466684_+SINEAluAluSz6
CAediting_854815chr11_118466694_+SINEAluAluSz6
CAediting_854816chr11_118466695_+SINEAluAluSz6
CAediting_854817chr11_118466721_+SINEAluAluSz6
CAediting_854818chr11_118466727_+SINEAluAluSz6
CAediting_854819chr11_118466781_+SINEAluAluSz6
CAediting_854820chr11_118466787_+SINEAluAluSz6
CAediting_854821chr11_118466922_+SINEAluFLAM_A
CAediting_854822chr11_118467152_+SINEAluAluSz
CAediting_854823chr11_118475688_+SINEAluAluSc8
CAediting_854824chr11_118476460_+SINEAluAluJb
CAediting_854825chr11_118476464_+SINEAluAluJb
CAediting_854826chr11_118476467_+SINEAluAluJb
CAediting_854827chr11_118483278_+SINEAluAluYe5
CAediting_854828chr11_118497187_+SINEAluAluSp
CAediting_854829chr11_118497189_+SINEAluAluSp

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RNA A-to-I editing events in the alternative splicing sites for KMT2A

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000118058.19.KMT2A.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000118058.19.KMT2A.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for KMT2A

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for KMT2A

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for KMT2A

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000118058.19ENST00000534358hsa-miR-605-3p1185241711185241777mer-m8118524157118524178164-19.66
CAediting_688080chr9_63819626_+ENSG00000118058.19ENST00000534358hsa-miR-4477b1185239141185239218mer-1a118523900118523921146-8.8
CAediting_1054808chr15_66496985_-ENSG00000118058.19ENST00000389506hsa-miR-45121185223991185224046mer118522384118522405140-20.84
CAediting_1054808chr15_66496985_-ENSG00000118058.19ENST00000389506hsa-miR-45121185226251185226328mer-1a118522611118522632149-18.37
CAediting_1160181chr17_7017644_-ENSG00000118058.19ENST00000389506hsa-miR-195-3p1185227771185227848mer-1a118522763118522784145-9.76
CAediting_1054808chr15_66496985_-ENSG00000118058.19ENST00000534358hsa-miR-45121185223991185224046mer118522384118522405140-20.84
CAediting_1054808chr15_66496985_-ENSG00000118058.19ENST00000534358hsa-miR-45121185226251185226328mer-1a118522611118522632149-18.37
CAediting_1229415chr17_67471547_+ENSG00000118058.19ENST00000534358hsa-miR-548aa1185244441185244507mer-m8118524427118524451147-13.05
CAediting_1229415chr17_67471547_+ENSG00000118058.19ENST00000534358hsa-miR-548aa1185260421185260487mer-m8118526015118526049142-12.26
CAediting_1160181chr17_7017644_-ENSG00000118058.19ENST00000534358hsa-miR-195-3p1185244561185244627mer-m8118524440118524463151-12.83
CAediting_1160181chr17_7017644_-ENSG00000118058.19ENST00000534358hsa-miR-195-3p1185227771185227848mer-1a118522763118522784145-9.76
CAediting_1368054chr19_46709310_-ENSG00000118058.19ENST00000534358hsa-miR-320e1185252801185252878mer-1a118525265118525287147-19.32
CAediting_86358chr1_109598906_+ENSG00000118058.19ENST00000534358hsa-miR-197-5p1185249651185249717mer-m8118524951118524972163-28.29
CAediting_1399425chr20_1392958_-ENSG00000118058.19ENST00000534358hsa-miR-6869-5p1185245671185245737mer-m8118524554118524574144-16.47
CAediting_442554chr5_154685830_+ENSG00000118058.19ENST00000534358hsa-miR-13031185251191185251268mer-1a118525104118525126147-17.4
CAediting_468389chr6_31355314_-ENSG00000118058.19ENST00000534358hsa-miR-6891-5p1185248721185248798mer-1a118524861118524879150-24.64

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_604450chr7_133034877_-ENSG00000118058.19ENST00000389506hsa-miR-36541185232941185233007mer-m8118523285118523301152-18.37
CAediting_396018chr5_1062918_-ENSG00000118058.19ENST00000389506hsa-miR-46351185233241185233296mer118523310118523330141-13.44
CAediting_524911chr7_5495852_-ENSG00000118058.19ENST00000389506hsa-miR-589-3p1185235301185235367mer-m8118523515118523537148-13
CAediting_86358chr1_109598906_+ENSG00000118058.19ENST00000534358hsa-miR-197-5p1185245661185245738mer-1a118524551118524573147-18.75
CAediting_604450chr7_133034877_-ENSG00000118058.19ENST00000534358hsa-miR-36541185232941185233007mer-m8118523285118523301152-18.37
CAediting_396018chr5_1062918_-ENSG00000118058.19ENST00000534358hsa-miR-46351185233241185233296mer118523310118523330141-13.44
CAediting_1229413chr17_67471544_+ENSG00000118058.19ENST00000534358hsa-miR-548aa1185258911185258977mer-m8118525868118525898141-12.89
CAediting_1229415chr17_67471547_+ENSG00000118058.19ENST00000534358hsa-miR-548aa1185258911185258977mer-m8118525868118525898141-12.89
CAediting_1229414chr17_67471546_+ENSG00000118058.19ENST00000534358hsa-miR-548aa1185258911185258977mer-m8118525868118525898141-12.89
CAediting_1229413chr17_67471544_+ENSG00000118058.19ENST00000534358hsa-miR-548aa1185259611185259677mer-m8118525944118525968150-6.88
CAediting_1229415chr17_67471547_+ENSG00000118058.19ENST00000534358hsa-miR-548aa1185259611185259677mer-m8118525944118525968150-6.88
CAediting_1229414chr17_67471546_+ENSG00000118058.19ENST00000534358hsa-miR-548aa1185259611185259677mer-m8118525944118525968150-6.88
CAediting_524911chr7_5495852_-ENSG00000118058.19ENST00000534358hsa-miR-589-3p1185235301185235367mer-m8118523515118523537148-13
CAediting_524911chr7_5495852_-ENSG00000118058.19ENST00000534358hsa-miR-589-3p1185263261185263327mer-m8118526313118526333147-18.11
CAediting_748296chr10_51299626_+ENSG00000118058.19ENST00000534358hsa-miR-605-3p1185243911185243977mer-m8118524378118524398154-18.09
CAediting_980496chr14_31014685_-ENSG00000118058.19ENST00000534358hsa-miR-624-3p1185241651185241717mer-m8118524151118524172149-14.68
CAediting_468389chr6_31355314_-ENSG00000118058.19ENST00000534358hsa-miR-6891-5p1185239711185239766mer118523959118523977141-23.12
CAediting_468389chr6_31355314_-ENSG00000118058.19ENST00000534358hsa-miR-6891-5p1185262611185262677mer-m8118526250118526268141-18

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for KMT2A

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for KMT2A

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for KMT2A

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for KMT2A

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
STADCAediting_854743chr11_118449479_+0.006297279694314820.00397909246.853

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RelatedDrugs for KMT2A

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for KMT2A

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
KMT2AC2826025Mixed phenotype acute leukemia3ORPHANET
KMT2AC0023418leukemia2CTD_human
KMT2AC0023452Childhood Acute Lymphoblastic Leukemia2CTD_human
KMT2AC0023453L2 Acute Lymphoblastic Leukemia2CTD_human
KMT2AC0023466Leukemia, Monocytic, Chronic2CTD_human
KMT2AC0023467Leukemia, Myelocytic, Acute2CTD_human
KMT2AC0023470Myeloid Leukemia2CTD_human
KMT2AC0026998Acute Myeloid Leukemia, M12CTD_human
KMT2AC1854630Growth Deficiency and Mental Retardation with Facial Dysmorphism2CTD_human;GENOMICS_ENGLAND;ORPHANET
KMT2AC1879321Acute Myeloid Leukemia (AML-M2)2CTD_human
KMT2AC1961102Precursor Cell Lymphoblastic Leukemia Lymphoma2CTD_human
KMT2AC0001418Adenocarcinoma1CTD_human
KMT2AC0004403Autosome Abnormalities1CTD_human
KMT2AC0005684Malignant neoplasm of urinary bladder1CTD_human
KMT2AC0005695Bladder Neoplasm1CTD_human
KMT2AC0007138Carcinoma, Transitional Cell1CTD_human
KMT2AC0008625Chromosome Aberrations1CTD_human
KMT2AC0023448Lymphoid leukemia1CTD_human
KMT2AC0023465Acute monocytic leukemia1CTD_human
KMT2AC0023479Acute myelomonocytic leukemia1CTD_human
KMT2AC0024623Malignant neoplasm of stomach1CTD_human
KMT2AC0033578Prostatic Neoplasms1CTD_human
KMT2AC0036341Schizophrenia1PSYGENET
KMT2AC0038356Stomach Neoplasms1CTD_human
KMT2AC0149925Small cell carcinoma of lung1CTD_human
KMT2AC0205641Adenocarcinoma, Basal Cell1CTD_human
KMT2AC0205642Adenocarcinoma, Oxyphilic1CTD_human
KMT2AC0205643Carcinoma, Cribriform1CTD_human
KMT2AC0205644Carcinoma, Granular Cell1CTD_human
KMT2AC0205645Adenocarcinoma, Tubular1CTD_human
KMT2AC0270972Cornelia De Lange Syndrome1ORPHANET
KMT2AC0280141Acute Undifferentiated Leukemia1ORPHANET
KMT2AC0376358Malignant neoplasm of prostate1CTD_human
KMT2AC0856823Undifferentiated type acute leukemia1ORPHANET
KMT2AC1535926Neurodevelopmental Disorders1CTD_human
KMT2AC1708349Hereditary Diffuse Gastric Cancer1CTD_human
KMT2AC2239176Liver carcinoma1CTD_human
KMT2AC2930974Acute erythroleukemia1CTD_human
KMT2AC2930975Acute erythroleukemia - M6a subtype1CTD_human
KMT2AC2930976Acute myeloid leukemia FAB-M61CTD_human
KMT2AC2930977Acute erythroleukemia - M6b subtype1CTD_human