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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: MCM7 (CAeditome ID:4176) |
Gene summary for MCM7 |
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Gene information | Gene symbol | MCM7 | Gene ID | 4176 |
Gene name | minichromosome maintenance complex component 7 | |
Synonyms | CDC47|MCM2|P1.1-MCM3|P1CDC47|P85MCM|PNAS146|PPP1R104 | |
Cytomap | 7q22.1 | |
Type of gene | protein-coding | |
Description | DNA replication licensing factor MCM7CDC47 homologhomolog of S. cerevisiae Cdc47minichromosome maintenance deficient 7protein phosphatase 1, regulatory subunit 104 | |
Modification date | 20210518 | |
UniProtAcc | P33993 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
MCM7 | GO:0005730 | DNA replication licensing factor MCM7 | 21383955 |
MCM7 | GO:0003678 | DNA replication licensing factor MCM7 | 9305914 |
MCM7 | GO:0005634 | DNA replication licensing factor MCM7 | 21383955 |
MCM7 | GO:0005654 | DNA replication licensing factor MCM7 | 0000052 |
MCM7 | GO:0005829 | DNA replication licensing factor MCM7 | 0000052 |
MCM7 | GO:0042555 | DNA replication licensing factor MCM7 | 17296731 |
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RNA A-to-I events for MCM7 |
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CAediting_579740(100094282, -), CAediting_579741(100096453, -), CAediting_579742(100097205, -), |
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RNA editing positional annotations for MCM7 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_579740 | chr7_100094282_- | nonsynonymous SNV | ENST00000303887.8 | c.A1739G | p.Y580C | D | D | D |
CAediting_579740 | chr7_100094282_- | nonsynonymous SNV | ENST00000354230.6 | c.A1211G | p.Y404C | D | D | D |
CAediting_579740 | chr7_100094282_- | nonsynonymous SNV | ENST00000621318.3 | c.A1211G | p.Y404C | D | D | D |
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CAeditome ID | Position | Variant type |
CAediting_579740 | chr7_100094282_- | exonic |
CAediting_579741 | chr7_100096453_- | ncRNA_intronic |
CAediting_579742 | chr7_100097205_- | ncRNA_intronic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_579741 | chr7_100096453_- | SINE | Alu | AluJr4 |
CAediting_579742 | chr7_100097205_- | SINE | Alu | AluJr4 |
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RNA A-to-I editing events in the alternative splicing sites for MCM7 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MCM7 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for MCM7 |
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The effects of the RNA editing to the miRNA binding sites for MCM7 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_524911 | chr7_5495852_- | ENSG00000166508.16 | ENST00000491245 | hsa-miR-589-3p | 100094173 | 100094179 | 7mer-m8 | 100094173 | 100094195 | 140 | -13.83 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for MCM7 |
![]() * Click on the image to enlarge it in a new window. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
CAediting_579740 | ENST00000303887.8 | chr7_100094282_- | -1159.70 | -1158.20 | -1159.70 |
CAediting_579740 | ENST00000354230.6 | chr7_100094282_- | -1187.30 | -1186.40 | -1187.30 |
CAediting_579740 | ENST00000485286.4 | chr7_100094282_- | -1153.50 | -1152.60 | -1153.50 |
CAediting_579740 | ENST00000489841.4 | chr7_100094282_- | -967.20 | -962.20 | -967.20 |
CAediting_579740 | ENST00000491245.5 | chr7_100094282_- | -238.00 | -235.90 | -238.00 |
CAediting_579740 | ENST00000493352.1 | chr7_100094282_- | -204.00 | -201.00 | -204.00 |
CAediting_579740 | ENST00000621318.3 | chr7_100094282_- | -1209.60 | -1205.20 | -1209.60 |
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Relation with ADAR for MCM7 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for MCM7 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for MCM7 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for MCM7 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MCM7 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |