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Editing gene: MC1R (CAeditome ID:4157)

Gene summary for MC1R

Gene summary

Gene information	Gene symbol	MC1R
	Gene ID	4157
	Gene name	melanocortin 1 receptor
	Synonyms	CMM5\|MSH-R\|SHEP2
	Cytomap	16q24.3
	Type of gene	protein-coding
	Description	melanocyte-stimulating hormone receptorMC1-Ralpha melanocyte stimulating hormone receptormelanotropin receptor
	Modification date	20210531
	UniProtAcc	Q01726
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
MC1R	GO:0007189	Melanocyte-stimulating hormone receptor	19329486
MC1R	GO:0007189	Melanocyte-stimulating hormone receptor	19743876
MC1R	GO:0070914	Melanocyte-stimulating hormone receptor	18292087
MC1R	GO:0005886	Melanocyte-stimulating hormone receptor	19452503
MC1R	GO:0005886	Melanocyte-stimulating hormone receptor	31097585

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RNA A-to-I events for MC1R

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000258839.2

RNA A-to-I editing events in Cancer.

CAediting_1146304(89916375, +), CAediting_1146305(89916383, +), CAediting_1146306(89916422, +), CAediting_1146307(89916435, +), CAediting_1146308(89916436, +), CAediting_1146309(89916450, +), CAediting_1146310(89916451, +), CAediting_1146311(89916482, +), CAediting_1146312(89916484, +), CAediting_1146313(89916486, +), CAediting_1146314(89916487, +), CAediting_1146315(89916488, +), CAediting_1146316(89916489, +), CAediting_1146317(89916490, +), CAediting_1146318(89916509, +), CAediting_1146319(89916519, +), CAediting_1146320(89916525, +), CAediting_1146321(89916533, +), CAediting_1146322(89916555, +), CAediting_1146323(89916560, +), CAediting_1146324(89916561, +), CAediting_1146325(89916572, +), CAediting_1146326(89916579, +), CAediting_1146327(89916589, +), CAediting_1146328(89916592, +), CAediting_1146329(89916595, +), CAediting_1146330(89916641, +), CAediting_1146331(89916642, +), CAediting_1146332(89916648, +), CAediting_1146333(89916650, +), CAediting_1146334(89916691, +), CAediting_1146335(89916692, +), CAediting_1146336(89916697, +), CAediting_1146337(89916737, +), CAediting_1146338(89916745, +), CAediting_1146339(89916746, +), CAediting_1146340(89916763, +), CAediting_1146341(89916782, +), CAediting_1146342(89916784, +), CAediting_1146343(89916785, +), CAediting_1146344(89916786, +), CAediting_1146345(89916787, +), CAediting_1146346(89916788, +), CAediting_1146347(89916789, +), CAediting_1146348(89916794, +), CAediting_1146349(89916797, +), CAediting_1146350(89916813, +), CAediting_1146351(89916831, +), CAediting_1146352(89916835, +), CAediting_1146353(89916866, +), CAediting_1146354(89916891, +), CAediting_1146355(89916895, +), CAediting_1146356(89916896, +), CAediting_1146357(89916899, +), CAediting_1146358(89917058, +), CAediting_1146359(89917133, +), CAediting_1146360(89917155, +), CAediting_1146361(89917161, +), CAediting_1146362(89917164, +), CAediting_1146363(89917186, +), CAediting_1146364(89917191, +), CAediting_1146365(89917202, +), CAediting_1146366(89917231, +), CAediting_1146367(89917239, +), CAediting_1146368(89917240, +), CAediting_1146369(89917248, +), CAediting_1146370(89917253, +), CAediting_1146371(89917281, +), CAediting_1146372(89917305, +), CAediting_1146373(89917346, +), CAediting_1146374(89917357, +), CAediting_1146375(89917362, +), CAediting_1146376(89917363, +), CAediting_1146377(89917376, +), CAediting_1146378(89917382, +), CAediting_1146379(89917383, +), CAediting_1146380(89917400, +), CAediting_1146381(89917410, +), CAediting_1146382(89917420, +), CAediting_1146383(89917451, +), CAediting_1146384(89917456, +), CAediting_1146385(89917480, +), CAediting_1146386(89917493, +), CAediting_1146387(89917531, +), CAediting_1146388(89917532, +), CAediting_1146389(89917533, +),

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RNA editing positional annotations for MC1R using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1146304	chr16_89916375_+	ncRNA_intronic
CAediting_1146305	chr16_89916383_+	ncRNA_intronic
CAediting_1146306	chr16_89916422_+	ncRNA_intronic
CAediting_1146307	chr16_89916435_+	ncRNA_intronic
CAediting_1146308	chr16_89916436_+	ncRNA_intronic
CAediting_1146309	chr16_89916450_+	ncRNA_intronic
CAediting_1146310	chr16_89916451_+	ncRNA_intronic
CAediting_1146311	chr16_89916482_+	ncRNA_intronic
CAediting_1146312	chr16_89916484_+	ncRNA_intronic
CAediting_1146313	chr16_89916486_+	ncRNA_intronic
CAediting_1146314	chr16_89916487_+	ncRNA_intronic
CAediting_1146315	chr16_89916488_+	ncRNA_intronic
CAediting_1146316	chr16_89916489_+	ncRNA_intronic
CAediting_1146317	chr16_89916490_+	ncRNA_intronic
CAediting_1146318	chr16_89916509_+	ncRNA_intronic
CAediting_1146319	chr16_89916519_+	ncRNA_intronic
CAediting_1146320	chr16_89916525_+	ncRNA_intronic
CAediting_1146321	chr16_89916533_+	ncRNA_intronic
CAediting_1146322	chr16_89916555_+	ncRNA_intronic
CAediting_1146323	chr16_89916560_+	ncRNA_intronic
CAediting_1146324	chr16_89916561_+	ncRNA_intronic
CAediting_1146325	chr16_89916572_+	ncRNA_intronic
CAediting_1146326	chr16_89916579_+	ncRNA_intronic
CAediting_1146327	chr16_89916589_+	ncRNA_intronic
CAediting_1146328	chr16_89916592_+	ncRNA_intronic
CAediting_1146329	chr16_89916595_+	ncRNA_intronic
CAediting_1146330	chr16_89916641_+	ncRNA_intronic
CAediting_1146331	chr16_89916642_+	ncRNA_intronic
CAediting_1146332	chr16_89916648_+	ncRNA_intronic
CAediting_1146333	chr16_89916650_+	ncRNA_intronic
CAediting_1146334	chr16_89916691_+	ncRNA_intronic
CAediting_1146335	chr16_89916692_+	ncRNA_intronic
CAediting_1146336	chr16_89916697_+	ncRNA_intronic
CAediting_1146337	chr16_89916737_+	ncRNA_intronic
CAediting_1146338	chr16_89916745_+	ncRNA_intronic
CAediting_1146339	chr16_89916746_+	ncRNA_intronic
CAediting_1146340	chr16_89916763_+	ncRNA_intronic
CAediting_1146341	chr16_89916782_+	ncRNA_intronic
CAediting_1146342	chr16_89916784_+	ncRNA_intronic
CAediting_1146343	chr16_89916785_+	ncRNA_intronic
CAediting_1146344	chr16_89916786_+	ncRNA_intronic
CAediting_1146345	chr16_89916787_+	ncRNA_intronic
CAediting_1146346	chr16_89916788_+	ncRNA_intronic
CAediting_1146347	chr16_89916789_+	ncRNA_intronic
CAediting_1146348	chr16_89916794_+	ncRNA_intronic
CAediting_1146349	chr16_89916797_+	ncRNA_intronic
CAediting_1146350	chr16_89916813_+	ncRNA_intronic
CAediting_1146351	chr16_89916831_+	ncRNA_intronic
CAediting_1146352	chr16_89916835_+	ncRNA_intronic
CAediting_1146353	chr16_89916866_+	ncRNA_intronic
CAediting_1146354	chr16_89916891_+	ncRNA_intronic
CAediting_1146355	chr16_89916895_+	ncRNA_intronic
CAediting_1146356	chr16_89916896_+	ncRNA_intronic
CAediting_1146357	chr16_89916899_+	ncRNA_intronic
CAediting_1146358	chr16_89917058_+	ncRNA_intronic
CAediting_1146359	chr16_89917133_+	ncRNA_intronic
CAediting_1146360	chr16_89917155_+	ncRNA_intronic
CAediting_1146361	chr16_89917161_+	ncRNA_intronic
CAediting_1146362	chr16_89917164_+	ncRNA_intronic
CAediting_1146363	chr16_89917186_+	ncRNA_intronic
CAediting_1146364	chr16_89917191_+	ncRNA_intronic
CAediting_1146365	chr16_89917202_+	ncRNA_intronic
CAediting_1146366	chr16_89917231_+	ncRNA_intronic
CAediting_1146367	chr16_89917239_+	ncRNA_intronic
CAediting_1146368	chr16_89917240_+	ncRNA_intronic
CAediting_1146369	chr16_89917248_+	ncRNA_intronic
CAediting_1146370	chr16_89917253_+	ncRNA_intronic
CAediting_1146371	chr16_89917281_+	ncRNA_intronic
CAediting_1146372	chr16_89917305_+	ncRNA_intronic
CAediting_1146373	chr16_89917346_+	ncRNA_intronic
CAediting_1146374	chr16_89917357_+	ncRNA_intronic
CAediting_1146375	chr16_89917362_+	ncRNA_intronic
CAediting_1146376	chr16_89917363_+	ncRNA_intronic
CAediting_1146377	chr16_89917376_+	ncRNA_intronic
CAediting_1146378	chr16_89917382_+	ncRNA_intronic
CAediting_1146379	chr16_89917383_+	ncRNA_intronic
CAediting_1146380	chr16_89917400_+	ncRNA_intronic
CAediting_1146381	chr16_89917410_+	ncRNA_intronic
CAediting_1146382	chr16_89917420_+	ncRNA_intronic
CAediting_1146383	chr16_89917451_+	ncRNA_intronic
CAediting_1146384	chr16_89917456_+	ncRNA_intronic
CAediting_1146385	chr16_89917480_+	ncRNA_intronic
CAediting_1146386	chr16_89917493_+	ncRNA_intronic
CAediting_1146387	chr16_89917531_+	ncRNA_intronic
CAediting_1146388	chr16_89917532_+	ncRNA_intronic
CAediting_1146389	chr16_89917533_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1146304	chr16_89916375_+	SINE	Alu	AluSc8
CAediting_1146305	chr16_89916383_+	SINE	Alu	AluSc8
CAediting_1146306	chr16_89916422_+	SINE	Alu	AluSc8
CAediting_1146307	chr16_89916435_+	SINE	Alu	AluSc8
CAediting_1146308	chr16_89916436_+	SINE	Alu	AluSc8
CAediting_1146309	chr16_89916450_+	SINE	Alu	AluSc8
CAediting_1146310	chr16_89916451_+	SINE	Alu	AluSc8
CAediting_1146311	chr16_89916482_+	SINE	Alu	AluSc8
CAediting_1146312	chr16_89916484_+	SINE	Alu	AluSc8
CAediting_1146313	chr16_89916486_+	SINE	Alu	AluSc8
CAediting_1146314	chr16_89916487_+	SINE	Alu	AluSc8
CAediting_1146315	chr16_89916488_+	SINE	Alu	AluSc8
CAediting_1146316	chr16_89916489_+	SINE	Alu	AluSc8
CAediting_1146317	chr16_89916490_+	SINE	Alu	AluSc8
CAediting_1146318	chr16_89916509_+	SINE	Alu	AluSc8
CAediting_1146319	chr16_89916519_+	SINE	Alu	AluSc8
CAediting_1146320	chr16_89916525_+	SINE	Alu	AluSc8
CAediting_1146321	chr16_89916533_+	SINE	Alu	AluSc8
CAediting_1146322	chr16_89916555_+	SINE	Alu	AluSc8
CAediting_1146323	chr16_89916560_+	SINE	Alu	AluSc8
CAediting_1146324	chr16_89916561_+	SINE	Alu	AluSc8
CAediting_1146325	chr16_89916572_+	SINE	Alu	AluSc8
CAediting_1146326	chr16_89916579_+	SINE	Alu	AluSc8
CAediting_1146327	chr16_89916589_+	SINE	Alu	AluSc8
CAediting_1146328	chr16_89916592_+	SINE	Alu	AluSc8
CAediting_1146329	chr16_89916595_+	SINE	Alu	AluSc8
CAediting_1146330	chr16_89916641_+	SINE	Alu	AluSc8
CAediting_1146331	chr16_89916642_+	SINE	Alu	AluSc8
CAediting_1146332	chr16_89916648_+	SINE	Alu	AluSc8
CAediting_1146333	chr16_89916650_+	SINE	Alu	AluSc8
CAediting_1146334	chr16_89916691_+	SINE	Alu	AluSx1
CAediting_1146335	chr16_89916692_+	SINE	Alu	AluSx1
CAediting_1146336	chr16_89916697_+	SINE	Alu	AluSx1
CAediting_1146337	chr16_89916737_+	SINE	Alu	AluSx1
CAediting_1146338	chr16_89916745_+	SINE	Alu	AluSx1
CAediting_1146339	chr16_89916746_+	SINE	Alu	AluSx1
CAediting_1146340	chr16_89916763_+	SINE	Alu	AluSx1
CAediting_1146341	chr16_89916782_+	SINE	Alu	AluSx1
CAediting_1146342	chr16_89916784_+	SINE	Alu	AluSx1
CAediting_1146343	chr16_89916785_+	SINE	Alu	AluSx1
CAediting_1146344	chr16_89916786_+	SINE	Alu	AluSx1
CAediting_1146345	chr16_89916787_+	SINE	Alu	AluSx1
CAediting_1146346	chr16_89916788_+	SINE	Alu	AluSx1
CAediting_1146347	chr16_89916789_+	SINE	Alu	AluSx1
CAediting_1146348	chr16_89916794_+	SINE	Alu	AluSx1
CAediting_1146349	chr16_89916797_+	SINE	Alu	AluSx1
CAediting_1146350	chr16_89916813_+	SINE	Alu	AluSx1
CAediting_1146351	chr16_89916831_+	SINE	Alu	AluSx1
CAediting_1146352	chr16_89916835_+	SINE	Alu	AluSx1
CAediting_1146353	chr16_89916866_+	SINE	Alu	AluSx1
CAediting_1146354	chr16_89916891_+	SINE	Alu	AluSx1
CAediting_1146355	chr16_89916895_+	SINE	Alu	AluSx1
CAediting_1146356	chr16_89916896_+	SINE	Alu	AluSx1
CAediting_1146357	chr16_89916899_+	SINE	Alu	AluSx1
CAediting_1146358	chr16_89917058_+	SINE	Alu	AluSg
CAediting_1146359	chr16_89917133_+	SINE	Alu	AluSg
CAediting_1146360	chr16_89917155_+	SINE	Alu	AluSg
CAediting_1146361	chr16_89917161_+	SINE	Alu	AluSg
CAediting_1146362	chr16_89917164_+	SINE	Alu	AluSg
CAediting_1146363	chr16_89917186_+	SINE	Alu	AluSg
CAediting_1146364	chr16_89917191_+	SINE	Alu	AluSg
CAediting_1146365	chr16_89917202_+	SINE	Alu	AluSg
CAediting_1146366	chr16_89917231_+	SINE	Alu	AluSg
CAediting_1146367	chr16_89917239_+	SINE	Alu	AluSg
CAediting_1146368	chr16_89917240_+	SINE	Alu	AluSg
CAediting_1146369	chr16_89917248_+	SINE	Alu	AluSg
CAediting_1146370	chr16_89917253_+	SINE	Alu	AluSg
CAediting_1146372	chr16_89917305_+	SINE	Alu	AluSq2
CAediting_1146373	chr16_89917346_+	SINE	Alu	AluSq2
CAediting_1146374	chr16_89917357_+	SINE	Alu	AluSq2
CAediting_1146375	chr16_89917362_+	SINE	Alu	AluSq2
CAediting_1146376	chr16_89917363_+	SINE	Alu	AluSq2
CAediting_1146377	chr16_89917376_+	SINE	Alu	AluSq2
CAediting_1146378	chr16_89917382_+	SINE	Alu	AluSq2
CAediting_1146379	chr16_89917383_+	SINE	Alu	AluSq2
CAediting_1146380	chr16_89917400_+	SINE	Alu	AluSq2
CAediting_1146381	chr16_89917410_+	SINE	Alu	AluSq2
CAediting_1146382	chr16_89917420_+	SINE	Alu	AluSq2
CAediting_1146383	chr16_89917451_+	SINE	Alu	AluSq2
CAediting_1146384	chr16_89917456_+	SINE	Alu	AluSq2
CAediting_1146385	chr16_89917480_+	SINE	Alu	AluSq2
CAediting_1146386	chr16_89917493_+	SINE	Alu	AluSq2
CAediting_1146387	chr16_89917531_+	SINE	Alu	AluSq2
CAediting_1146388	chr16_89917532_+	SINE	Alu	AluSq2
CAediting_1146389	chr16_89917533_+	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for MC1R

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000258839.2.MC1R.

Correlation between RNA A-to-I editing and PSI for ENSG00000258839.2.MC1R.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MC1R

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for MC1R

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for MC1R

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MC1R

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for MC1R

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for MC1R

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_1146335	chr16_89916692_+	0.00293392841597142	-0.404542544808268
BRCA	pathologic_stage	CAediting_1146335	chr16_89916692_+	0.00682427385084667	0.32280864752107

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Relation with survival for MC1R

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for MC1R

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
MC1R	Q01726	DB04931	Afamelanotide	Melanocyte-stimulating hormone receptor	SmallMoleculeDrug	approved\|investigational
MC1R	Q01726	DB11653	Bremelanotide	Melanocyte-stimulating hormone receptor	SmallMoleculeDrug	approved\|investigational

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RelatedDiseases for MC1R

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
MC1R	C0025202	melanoma	3	CTD_human
MC1R	C2314896	Familial Atypical Mole Melanoma Syndrome	2	ORPHANET
MC1R	C2751295	MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 5	2	CTD_human;UNIPROT
MC1R	C0011570	Mental Depression	1	PSYGENET
MC1R	C0011581	Depressive disorder	1	PSYGENET
MC1R	C0020429	Hyperalgesia	1	CTD_human
MC1R	C0042900	Vitiligo	1	CTD_human
MC1R	C0268495	Oculocutaneous albinism type 2	1	CTD_human;ORPHANET
MC1R	C0458247	Allodynia	1	CTD_human
MC1R	C0751211	Hyperalgesia, Primary	1	CTD_human
MC1R	C0751212	Hyperalgesia, Secondary	1	CTD_human
MC1R	C0751213	Tactile Allodynia	1	CTD_human
MC1R	C0751214	Hyperalgesia, Thermal	1	CTD_human
MC1R	C1318558	Congenital melanocytic nevus	1	ORPHANET
MC1R	C1368275	Pigmented Basal Cell Carcinoma	1	CTD_human
MC1R	C1842036	GIANT PIGMENTED HAIRY NEVUS	1	ORPHANET
MC1R	C2936719	Mechanical Allodynia	1	CTD_human
MC1R	C4721806	Carcinoma, Basal Cell	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene