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Editing gene: CCNYL2 (CAeditome ID:414194)

Gene summary for CCNYL2

Gene summary

Gene information	Gene symbol	CCNYL2
	Gene ID	414194
	Gene name	cyclin Y like 2 (pseudogene)
	Synonyms	C10orf21\|CCNYL2P\|bA178A10.2
	Cytomap	10q11.21
	Type of gene	pseudo
	Description	cyclin-Y-like protein 2
	Modification date	20210518
	UniProtAcc	.
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for CCNYL2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000182632.13

RNA A-to-I editing events in Cancer.

CAediting_745791(42408724, -), CAediting_745792(42408727, -), CAediting_745793(42408744, -), CAediting_745794(42408753, -), CAediting_745795(42408756, -), CAediting_745796(42408757, -), CAediting_745797(42408779, -), CAediting_745798(42408786, -), CAediting_745799(42408794, -), CAediting_745800(42408800, -), CAediting_745801(42408805, -), CAediting_745802(42408816, -), CAediting_745803(42408823, -), CAediting_745804(42408826, -), CAediting_745805(42408840, -), CAediting_745806(42408852, -), CAediting_745807(42408866, -), CAediting_745808(42408878, -), CAediting_745809(42408881, -), CAediting_745810(42408884, -), CAediting_745811(42408885, -), CAediting_745812(42408886, -), CAediting_745813(42408893, -), CAediting_745814(42408930, -), CAediting_745815(42408936, -), CAediting_745816(42408938, -), CAediting_745817(42408943, -), CAediting_745818(42408997, -), CAediting_745819(42409000, -), CAediting_745820(42409001, -), CAediting_745821(42409009, -), CAediting_745822(42409014, -), CAediting_745823(42409022, -), CAediting_745824(42409023, -), CAediting_745825(42409026, -), CAediting_745826(42409047, -), CAediting_745827(42409049, -), CAediting_745828(42409054, -), CAediting_745829(42409057, -), CAediting_745830(42409062, -), CAediting_745831(42409069, -), CAediting_745832(42409071, -), CAediting_745833(42409074, -), CAediting_745834(42409075, -), CAediting_745835(42409081, -), CAediting_745836(42409089, -), CAediting_745837(42409093, -), CAediting_745838(42409101, -), CAediting_745839(42409106, -), CAediting_745840(42409140, -), CAediting_745841(42409151, -), CAediting_745842(42409168, -), CAediting_745843(42423756, -), CAediting_745844(42423757, -), CAediting_745845(42424206, -), CAediting_745846(42426001, -), CAediting_745847(42426006, -), CAediting_745848(42426220, -), CAediting_745849(42426727, -), CAediting_745850(42426983, -), CAediting_745851(42426991, -), CAediting_745852(42427005, -), CAediting_745853(42427087, -), CAediting_745854(42427094, -), CAediting_745855(42427785, -), CAediting_745856(42427812, -), CAediting_745857(42427842, -), CAediting_745858(42427851, -), CAediting_745859(42427868, -), CAediting_745860(42427924, -), CAediting_745861(42427959, -), CAediting_745862(42427980, -), CAediting_745863(42429539, -), CAediting_745864(42429603, -), CAediting_745865(42429609, -), CAediting_745866(42429616, -), CAediting_745867(42429625, -), CAediting_745868(42429683, -), CAediting_745869(42429684, -), CAediting_745870(42429717, -), CAediting_745871(42429744, -), CAediting_745872(42429745, -), CAediting_745873(42431596, -), CAediting_745874(42431635, -),

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RNA editing positional annotations for CCNYL2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_745791	chr10_42408724_-	ncRNA_exonic
CAediting_745792	chr10_42408727_-	ncRNA_exonic
CAediting_745793	chr10_42408744_-	ncRNA_exonic
CAediting_745794	chr10_42408753_-	ncRNA_exonic
CAediting_745795	chr10_42408756_-	ncRNA_exonic
CAediting_745796	chr10_42408757_-	ncRNA_exonic
CAediting_745797	chr10_42408779_-	ncRNA_exonic
CAediting_745798	chr10_42408786_-	ncRNA_exonic
CAediting_745799	chr10_42408794_-	ncRNA_exonic
CAediting_745800	chr10_42408800_-	ncRNA_exonic
CAediting_745801	chr10_42408805_-	ncRNA_exonic
CAediting_745802	chr10_42408816_-	ncRNA_exonic
CAediting_745803	chr10_42408823_-	ncRNA_exonic
CAediting_745804	chr10_42408826_-	ncRNA_exonic
CAediting_745805	chr10_42408840_-	ncRNA_exonic
CAediting_745806	chr10_42408852_-	ncRNA_exonic
CAediting_745807	chr10_42408866_-	ncRNA_exonic
CAediting_745808	chr10_42408878_-	ncRNA_exonic
CAediting_745809	chr10_42408881_-	ncRNA_exonic
CAediting_745810	chr10_42408884_-	ncRNA_exonic
CAediting_745811	chr10_42408885_-	ncRNA_exonic
CAediting_745812	chr10_42408886_-	ncRNA_exonic
CAediting_745813	chr10_42408893_-	ncRNA_exonic
CAediting_745814	chr10_42408930_-	ncRNA_exonic
CAediting_745815	chr10_42408936_-	ncRNA_exonic
CAediting_745816	chr10_42408938_-	ncRNA_exonic
CAediting_745817	chr10_42408943_-	ncRNA_exonic
CAediting_745818	chr10_42408997_-	ncRNA_exonic
CAediting_745819	chr10_42409000_-	ncRNA_exonic
CAediting_745820	chr10_42409001_-	ncRNA_exonic
CAediting_745821	chr10_42409009_-	ncRNA_exonic
CAediting_745822	chr10_42409014_-	ncRNA_exonic
CAediting_745823	chr10_42409022_-	ncRNA_exonic
CAediting_745824	chr10_42409023_-	ncRNA_exonic
CAediting_745825	chr10_42409026_-	ncRNA_exonic
CAediting_745826	chr10_42409047_-	ncRNA_exonic
CAediting_745827	chr10_42409049_-	ncRNA_exonic
CAediting_745828	chr10_42409054_-	ncRNA_exonic
CAediting_745829	chr10_42409057_-	ncRNA_exonic
CAediting_745830	chr10_42409062_-	ncRNA_exonic
CAediting_745831	chr10_42409069_-	ncRNA_exonic
CAediting_745832	chr10_42409071_-	ncRNA_exonic
CAediting_745833	chr10_42409074_-	ncRNA_exonic
CAediting_745834	chr10_42409075_-	ncRNA_exonic
CAediting_745835	chr10_42409081_-	ncRNA_exonic
CAediting_745836	chr10_42409089_-	ncRNA_exonic
CAediting_745837	chr10_42409093_-	ncRNA_exonic
CAediting_745838	chr10_42409101_-	ncRNA_exonic
CAediting_745839	chr10_42409106_-	ncRNA_exonic
CAediting_745840	chr10_42409140_-	ncRNA_exonic
CAediting_745841	chr10_42409151_-	ncRNA_exonic
CAediting_745842	chr10_42409168_-	ncRNA_exonic
CAediting_745843	chr10_42423756_-	ncRNA_intronic
CAediting_745844	chr10_42423757_-	ncRNA_intronic
CAediting_745845	chr10_42424206_-	ncRNA_intronic
CAediting_745846	chr10_42426001_-	ncRNA_intronic
CAediting_745847	chr10_42426006_-	ncRNA_intronic
CAediting_745848	chr10_42426220_-	ncRNA_intronic
CAediting_745849	chr10_42426727_-	ncRNA_intronic
CAediting_745850	chr10_42426983_-	ncRNA_intronic
CAediting_745851	chr10_42426991_-	ncRNA_intronic
CAediting_745852	chr10_42427005_-	ncRNA_intronic
CAediting_745853	chr10_42427087_-	ncRNA_intronic
CAediting_745854	chr10_42427094_-	ncRNA_intronic
CAediting_745855	chr10_42427785_-	ncRNA_intronic
CAediting_745856	chr10_42427812_-	ncRNA_intronic
CAediting_745857	chr10_42427842_-	ncRNA_intronic
CAediting_745858	chr10_42427851_-	ncRNA_intronic
CAediting_745859	chr10_42427868_-	ncRNA_intronic
CAediting_745860	chr10_42427924_-	ncRNA_intronic
CAediting_745861	chr10_42427959_-	ncRNA_intronic
CAediting_745862	chr10_42427980_-	ncRNA_intronic
CAediting_745863	chr10_42429539_-	ncRNA_intronic
CAediting_745864	chr10_42429603_-	ncRNA_intronic
CAediting_745865	chr10_42429609_-	ncRNA_intronic
CAediting_745866	chr10_42429616_-	ncRNA_intronic
CAediting_745867	chr10_42429625_-	ncRNA_intronic
CAediting_745868	chr10_42429683_-	ncRNA_intronic
CAediting_745869	chr10_42429684_-	ncRNA_intronic
CAediting_745870	chr10_42429717_-	ncRNA_intronic
CAediting_745871	chr10_42429744_-	ncRNA_intronic
CAediting_745872	chr10_42429745_-	ncRNA_intronic
CAediting_745873	chr10_42431596_-	ncRNA_intronic
CAediting_745874	chr10_42431635_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_745791	chr10_42408724_-	SINE	Alu	FAM
CAediting_745792	chr10_42408727_-	SINE	Alu	FAM
CAediting_745793	chr10_42408744_-	SINE	Alu	FAM
CAediting_745794	chr10_42408753_-	SINE	Alu	FAM
CAediting_745795	chr10_42408756_-	SINE	Alu	FAM
CAediting_745796	chr10_42408757_-	SINE	Alu	FAM
CAediting_745797	chr10_42408779_-	SINE	Alu	FAM
CAediting_745798	chr10_42408786_-	SINE	Alu	FAM
CAediting_745799	chr10_42408794_-	SINE	Alu	FAM
CAediting_745800	chr10_42408800_-	SINE	Alu	FAM
CAediting_745801	chr10_42408805_-	SINE	Alu	FAM
CAediting_745802	chr10_42408816_-	SINE	Alu	FAM
CAediting_745803	chr10_42408823_-	SINE	Alu	FAM
CAediting_745804	chr10_42408826_-	SINE	Alu	FAM
CAediting_745805	chr10_42408840_-	SINE	Alu	FAM
CAediting_745818	chr10_42408997_-	SINE	Alu	FAM
CAediting_745819	chr10_42409000_-	SINE	Alu	FAM
CAediting_745820	chr10_42409001_-	SINE	Alu	FAM
CAediting_745821	chr10_42409009_-	SINE	Alu	FAM
CAediting_745822	chr10_42409014_-	SINE	Alu	FAM
CAediting_745823	chr10_42409022_-	SINE	Alu	FAM
CAediting_745824	chr10_42409023_-	SINE	Alu	FAM
CAediting_745825	chr10_42409026_-	SINE	Alu	FAM
CAediting_745826	chr10_42409047_-	SINE	Alu	FAM
CAediting_745827	chr10_42409049_-	SINE	Alu	FAM
CAediting_745828	chr10_42409054_-	SINE	Alu	FAM
CAediting_745829	chr10_42409057_-	SINE	Alu	FAM
CAediting_745830	chr10_42409062_-	SINE	Alu	FAM
CAediting_745831	chr10_42409069_-	SINE	Alu	FAM
CAediting_745832	chr10_42409071_-	SINE	Alu	FAM
CAediting_745833	chr10_42409074_-	SINE	Alu	FAM
CAediting_745834	chr10_42409075_-	SINE	Alu	FAM
CAediting_745835	chr10_42409081_-	SINE	Alu	FAM
CAediting_745836	chr10_42409089_-	SINE	Alu	FAM
CAediting_745837	chr10_42409093_-	SINE	Alu	FAM
CAediting_745838	chr10_42409101_-	SINE	Alu	FAM
CAediting_745839	chr10_42409106_-	SINE	Alu	FAM
CAediting_745843	chr10_42423756_-	SINE	Alu	AluJo
CAediting_745844	chr10_42423757_-	SINE	Alu	AluJo
CAediting_745845	chr10_42424206_-	SINE	Alu	FLAM_A
CAediting_745846	chr10_42426001_-	SINE	Alu	AluSq2
CAediting_745847	chr10_42426006_-	SINE	Alu	AluSq2
CAediting_745848	chr10_42426220_-	SINE	Alu	AluSq2
CAediting_745849	chr10_42426727_-	SINE	Alu	AluY
CAediting_745850	chr10_42426983_-	SINE	Alu	AluSq
CAediting_745851	chr10_42426991_-	SINE	Alu	AluSq
CAediting_745852	chr10_42427005_-	SINE	Alu	AluSq
CAediting_745853	chr10_42427087_-	SINE	Alu	AluSq
CAediting_745854	chr10_42427094_-	SINE	Alu	AluSq
CAediting_745855	chr10_42427785_-	SINE	Alu	AluJb
CAediting_745856	chr10_42427812_-	SINE	Alu	AluJb
CAediting_745857	chr10_42427842_-	SINE	Alu	AluJb
CAediting_745858	chr10_42427851_-	SINE	Alu	AluJb
CAediting_745859	chr10_42427868_-	SINE	Alu	AluJb
CAediting_745860	chr10_42427924_-	SINE	Alu	AluJb
CAediting_745861	chr10_42427959_-	SINE	Alu	AluJb
CAediting_745862	chr10_42427980_-	SINE	Alu	AluJb
CAediting_745863	chr10_42429539_-	SINE	Alu	AluSz6
CAediting_745864	chr10_42429603_-	SINE	Alu	AluSz6
CAediting_745865	chr10_42429609_-	SINE	Alu	AluSz6
CAediting_745866	chr10_42429616_-	SINE	Alu	AluSz6
CAediting_745867	chr10_42429625_-	SINE	Alu	AluSz6
CAediting_745868	chr10_42429683_-	SINE	Alu	AluSz6
CAediting_745869	chr10_42429684_-	SINE	Alu	AluSz6
CAediting_745870	chr10_42429717_-	SINE	Alu	AluSz6
CAediting_745871	chr10_42429744_-	SINE	Alu	AluSz6
CAediting_745872	chr10_42429745_-	SINE	Alu	AluSz6
CAediting_745873	chr10_42431596_-	SINE	Alu	AluSq2
CAediting_745874	chr10_42431635_-	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for CCNYL2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000182632.13.CCNYL2.

Correlation between RNA A-to-I editing and PSI for ENSG00000182632.13.CCNYL2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CCNYL2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CCNYL2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CCNYL2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CCNYL2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for CCNYL2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
OV	CAediting_745797	chr10_42408779_-	0.0205481545366636	0.306161807445361	.	.	.	.
OV	CAediting_745806	chr10_42408852_-	0.0381675591435473	0.28293408578084	.	.	.	.
SKCM	CAediting_745806	chr10_42408852_-	.	.	.	.	0.0294413348232438	0.308204522390087
SKCM	CAediting_745816	chr10_42408938_-	0.00201225403718371	0.407559987404933	.	.	.	.
SKCM	CAediting_745827	chr10_42409049_-	0.000326469888517825	0.463019698343935	.	.	.	.
KIRC	CAediting_745832	chr10_42409071_-	.	.	0.0101425882931017	0.356907972663006	.	.

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Relation with cancer stages for CCNYL2

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_745806	chr10_42408852_-	0.0467174544993725	-0.262267367722354
KIRC	pathologic_stage	CAediting_745803	chr10_42408823_-	0.0400255007712232	0.275290630399247
KIRC	pathologic_stage	CAediting_745806	chr10_42408852_-	0.0219755645402073	0.26079016826794
KIRC	pathologic_stage	CAediting_745828	chr10_42409054_-	0.02763249936165	0.299801217479261
OV	clinical_stage	CAediting_745797	chr10_42408779_-	0.0455896358572919	0.268282131474641
SKCM	pathologic_stage	CAediting_745816	chr10_42408938_-	0.0172355122726149	0.345913421370307

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Relation with survival for CCNYL2

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
KIRC	CAediting_745832	chr10_42409071_-	0.00386985367567638	0.0393923	9.10496

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RelatedDrugs for CCNYL2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CCNYL2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene