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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: MANBA (CAeditome ID:4126)

Gene summary for MANBA

check button Gene summary
Gene informationGene symbol

MANBA

Gene ID

4126

Gene namemannosidase beta
SynonymsMANB1
Cytomap

4q24

Type of geneprotein-coding
Descriptionbeta-mannosidasebeta-mannosidase Alysosomal beta A mannosidasemannanasemannasemannosidase, beta A, lysosomal
Modification date20210518
UniProtAcc

O00462

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
MANBA

GO:0004567

Beta-mannosidase

30552791


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RNA A-to-I events for MANBA

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000109323.7

check button RNA A-to-I editing events in Cancer.
CAediting_378266(102653957, -), CAediting_378267(102653960, -), CAediting_378268(102653975, -), CAediting_378269(102653982, -), CAediting_378270(102653985, -), CAediting_378271(102653986, -), CAediting_378272(102654002, -), CAediting_378273(102654125, -), CAediting_378274(102654133, -), CAediting_378275(102654134, -), CAediting_378276(102654152, -), CAediting_378277(102654162, -), CAediting_378278(102654163, -), CAediting_378279(102654165, -), CAediting_378280(102654170, -), CAediting_378281(102654174, -), CAediting_378282(102654179, -), CAediting_378283(102654199, -), CAediting_378284(102691524, -), CAediting_378285(102691549, -), CAediting_378286(102691552, -), CAediting_378287(102691584, -), CAediting_378288(102691588, -), CAediting_378289(102691598, -), CAediting_378290(102691603, -), CAediting_378291(102691614, -), CAediting_378292(102691617, -), CAediting_378293(102691621, -), CAediting_378294(102691627, -), CAediting_378295(102691628, -), CAediting_378296(102691630, -), CAediting_378297(102691644, -), CAediting_378298(102691665, -), CAediting_378299(102691669, -), CAediting_378300(102691672, -), CAediting_378301(102691677, -), CAediting_378302(102691678, -), CAediting_378303(102691690, -), CAediting_378304(102691696, -), CAediting_378305(102691708, -), CAediting_378306(102691720, -), CAediting_378307(102691727, -), CAediting_378308(102691783, -), CAediting_378309(102696179, -), CAediting_378310(102703165, -), CAediting_378311(102703228, -), CAediting_378312(102703957, -), CAediting_378313(102704309, -), CAediting_378314(102704342, -), CAediting_378315(102704345, -), CAediting_378316(102704346, -), CAediting_378317(102704347, -), CAediting_378318(102704348, -), CAediting_378319(102704352, -), CAediting_378320(102704358, -), CAediting_378321(102704361, -), CAediting_378322(102704420, -), CAediting_378323(102712580, -), CAediting_378324(102712611, -), CAediting_378325(102712627, -), CAediting_378326(102712634, -), CAediting_378327(102712647, -), CAediting_378328(102712657, -), CAediting_378329(102712683, -), CAediting_378330(102712692, -), CAediting_378331(102712694, -), CAediting_378332(102712695, -), CAediting_378333(102712703, -), CAediting_378334(102712723, -), CAediting_378335(102712725, -), CAediting_378336(102712749, -), CAediting_378337(102712778, -), CAediting_378338(102712780, -), CAediting_378339(102713643, -), CAediting_378340(102713705, -), CAediting_378341(102713784, -), CAediting_378342(102716197, -), CAediting_378343(102716209, -), CAediting_378344(102717475, -), CAediting_378345(102717488, -), CAediting_378346(102717489, -), CAediting_378347(102717493, -), CAediting_378348(102717536, -), CAediting_378349(102717550, -), CAediting_378350(102717589, -), CAediting_378351(102717612, -), CAediting_378352(102717613, -), CAediting_378353(102717621, -), CAediting_378354(102717640, -), CAediting_378355(102721283, -), CAediting_378356(102721807, -), CAediting_378357(102727050, -), CAediting_378358(102727373, -), CAediting_378359(102728266, -), CAediting_378360(102731962, -), CAediting_378361(102732135, -), CAediting_378362(102733462, -), CAediting_378363(102733469, -), CAediting_378364(102733478, -), CAediting_378365(102733486, -), CAediting_378366(102733492, -), CAediting_378367(102733521, -), CAediting_378368(102733529, -), CAediting_378369(102733607, -), CAediting_378370(102733633, -), CAediting_378371(102733634, -), CAediting_378372(102750791, -), CAediting_378373(102750797, -), CAediting_378374(102750801, -), CAediting_378375(102750804, -), CAediting_378376(102750805, -), CAediting_378377(102750830, -), CAediting_378378(102750844, -), CAediting_378379(102750907, -), CAediting_378380(102753838, -), CAediting_378381(102753853, -), CAediting_378382(102753861, -), CAediting_378383(102753862, -), CAediting_378384(102753871, -), CAediting_378385(102753890, -), CAediting_378386(102753891, -), CAediting_378387(102753903, -), CAediting_378388(102753921, -), CAediting_378389(102753922, -), CAediting_378390(102753928, -), CAediting_378391(102753942, -), CAediting_378392(102753966, -), CAediting_378393(102753995, -), CAediting_378394(102757157, -), CAediting_378395(102757158, -), CAediting_378396(102757201, -), CAediting_378397(102757229, -), CAediting_378398(102758619, -), CAediting_378399(102758640, -), CAediting_378400(102758668, -), CAediting_378401(102758675, -), CAediting_378402(102758687, -), CAediting_378403(102758707, -), CAediting_378404(102758711, -), CAediting_378405(102758713, -), CAediting_378406(102758720, -), CAediting_378407(102758725, -), CAediting_378408(102758796, -), CAediting_378409(102758813, -), CAediting_378410(102759259, -), CAediting_378411(102759260, -), CAediting_378412(102759265, -), CAediting_378413(102759268, -),

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RNA editing positional annotations for MANBA using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_378266chr4_102653957_-ncRNA_intronic
CAediting_378267chr4_102653960_-ncRNA_intronic
CAediting_378268chr4_102653975_-ncRNA_intronic
CAediting_378269chr4_102653982_-ncRNA_intronic
CAediting_378270chr4_102653985_-ncRNA_intronic
CAediting_378271chr4_102653986_-ncRNA_intronic
CAediting_378272chr4_102654002_-ncRNA_intronic
CAediting_378273chr4_102654125_-ncRNA_intronic
CAediting_378274chr4_102654133_-ncRNA_intronic
CAediting_378275chr4_102654134_-ncRNA_intronic
CAediting_378276chr4_102654152_-ncRNA_intronic
CAediting_378277chr4_102654162_-ncRNA_intronic
CAediting_378278chr4_102654163_-ncRNA_intronic
CAediting_378279chr4_102654165_-ncRNA_intronic
CAediting_378280chr4_102654170_-ncRNA_intronic
CAediting_378281chr4_102654174_-ncRNA_intronic
CAediting_378282chr4_102654179_-ncRNA_intronic
CAediting_378283chr4_102654199_-ncRNA_intronic
CAediting_378284chr4_102691524_-ncRNA_intronic
CAediting_378285chr4_102691549_-ncRNA_intronic
CAediting_378286chr4_102691552_-ncRNA_intronic
CAediting_378287chr4_102691584_-ncRNA_intronic
CAediting_378288chr4_102691588_-ncRNA_intronic
CAediting_378289chr4_102691598_-ncRNA_intronic
CAediting_378290chr4_102691603_-ncRNA_intronic
CAediting_378291chr4_102691614_-ncRNA_intronic
CAediting_378292chr4_102691617_-ncRNA_intronic
CAediting_378293chr4_102691621_-ncRNA_intronic
CAediting_378294chr4_102691627_-ncRNA_intronic
CAediting_378295chr4_102691628_-ncRNA_intronic
CAediting_378296chr4_102691630_-ncRNA_intronic
CAediting_378297chr4_102691644_-ncRNA_intronic
CAediting_378298chr4_102691665_-ncRNA_intronic
CAediting_378299chr4_102691669_-ncRNA_intronic
CAediting_378300chr4_102691672_-ncRNA_intronic
CAediting_378301chr4_102691677_-ncRNA_intronic
CAediting_378302chr4_102691678_-ncRNA_intronic
CAediting_378303chr4_102691690_-ncRNA_intronic
CAediting_378304chr4_102691696_-ncRNA_intronic
CAediting_378305chr4_102691708_-ncRNA_intronic
CAediting_378306chr4_102691720_-ncRNA_intronic
CAediting_378307chr4_102691727_-ncRNA_intronic
CAediting_378308chr4_102691783_-ncRNA_intronic
CAediting_378309chr4_102696179_-ncRNA_intronic
CAediting_378310chr4_102703165_-ncRNA_intronic
CAediting_378311chr4_102703228_-ncRNA_intronic
CAediting_378312chr4_102703957_-ncRNA_intronic
CAediting_378313chr4_102704309_-ncRNA_intronic
CAediting_378314chr4_102704342_-ncRNA_intronic
CAediting_378315chr4_102704345_-ncRNA_intronic
CAediting_378316chr4_102704346_-ncRNA_intronic
CAediting_378317chr4_102704347_-ncRNA_intronic
CAediting_378318chr4_102704348_-ncRNA_intronic
CAediting_378319chr4_102704352_-ncRNA_intronic
CAediting_378320chr4_102704358_-ncRNA_intronic
CAediting_378321chr4_102704361_-ncRNA_intronic
CAediting_378322chr4_102704420_-ncRNA_intronic
CAediting_378323chr4_102712580_-ncRNA_intronic
CAediting_378324chr4_102712611_-ncRNA_intronic
CAediting_378325chr4_102712627_-ncRNA_intronic
CAediting_378326chr4_102712634_-ncRNA_intronic
CAediting_378327chr4_102712647_-ncRNA_intronic
CAediting_378328chr4_102712657_-ncRNA_intronic
CAediting_378329chr4_102712683_-ncRNA_intronic
CAediting_378330chr4_102712692_-ncRNA_intronic
CAediting_378331chr4_102712694_-ncRNA_intronic
CAediting_378332chr4_102712695_-ncRNA_intronic
CAediting_378333chr4_102712703_-ncRNA_intronic
CAediting_378334chr4_102712723_-ncRNA_intronic
CAediting_378335chr4_102712725_-ncRNA_intronic
CAediting_378336chr4_102712749_-ncRNA_intronic
CAediting_378337chr4_102712778_-ncRNA_intronic
CAediting_378338chr4_102712780_-ncRNA_intronic
CAediting_378339chr4_102713643_-ncRNA_intronic
CAediting_378340chr4_102713705_-ncRNA_intronic
CAediting_378341chr4_102713784_-ncRNA_intronic
CAediting_378342chr4_102716197_-ncRNA_intronic
CAediting_378343chr4_102716209_-ncRNA_intronic
CAediting_378344chr4_102717475_-ncRNA_intronic
CAediting_378345chr4_102717488_-ncRNA_intronic
CAediting_378346chr4_102717489_-ncRNA_intronic
CAediting_378347chr4_102717493_-ncRNA_intronic
CAediting_378348chr4_102717536_-ncRNA_intronic
CAediting_378349chr4_102717550_-ncRNA_intronic
CAediting_378350chr4_102717589_-ncRNA_intronic
CAediting_378351chr4_102717612_-ncRNA_intronic
CAediting_378352chr4_102717613_-ncRNA_intronic
CAediting_378353chr4_102717621_-ncRNA_intronic
CAediting_378354chr4_102717640_-ncRNA_intronic
CAediting_378355chr4_102721283_-ncRNA_intronic
CAediting_378356chr4_102721807_-ncRNA_intronic
CAediting_378357chr4_102727050_-ncRNA_intronic
CAediting_378358chr4_102727373_-ncRNA_exonic
CAediting_378359chr4_102728266_-ncRNA_exonic
CAediting_378360chr4_102731962_-ncRNA_intronic
CAediting_378361chr4_102732135_-ncRNA_intronic
CAediting_378362chr4_102733462_-ncRNA_intronic
CAediting_378363chr4_102733469_-ncRNA_intronic
CAediting_378364chr4_102733478_-ncRNA_intronic
CAediting_378365chr4_102733486_-ncRNA_intronic
CAediting_378366chr4_102733492_-ncRNA_intronic
CAediting_378367chr4_102733521_-ncRNA_intronic
CAediting_378368chr4_102733529_-ncRNA_intronic
CAediting_378369chr4_102733607_-ncRNA_intronic
CAediting_378370chr4_102733633_-ncRNA_intronic
CAediting_378371chr4_102733634_-ncRNA_intronic
CAediting_378372chr4_102750791_-ncRNA_intronic
CAediting_378373chr4_102750797_-ncRNA_intronic
CAediting_378374chr4_102750801_-ncRNA_intronic
CAediting_378375chr4_102750804_-ncRNA_intronic
CAediting_378376chr4_102750805_-ncRNA_intronic
CAediting_378377chr4_102750830_-ncRNA_intronic
CAediting_378378chr4_102750844_-ncRNA_intronic
CAediting_378379chr4_102750907_-ncRNA_intronic
CAediting_378380chr4_102753838_-ncRNA_exonic
CAediting_378381chr4_102753853_-ncRNA_exonic
CAediting_378382chr4_102753861_-ncRNA_exonic
CAediting_378383chr4_102753862_-ncRNA_exonic
CAediting_378384chr4_102753871_-ncRNA_exonic
CAediting_378385chr4_102753890_-ncRNA_exonic
CAediting_378386chr4_102753891_-ncRNA_exonic
CAediting_378387chr4_102753903_-ncRNA_exonic
CAediting_378388chr4_102753921_-ncRNA_exonic
CAediting_378389chr4_102753922_-ncRNA_exonic
CAediting_378390chr4_102753928_-ncRNA_exonic
CAediting_378391chr4_102753942_-ncRNA_exonic
CAediting_378392chr4_102753966_-exonic
CAediting_378393chr4_102753995_-exonic
CAediting_378394chr4_102757157_-ncRNA_intronic
CAediting_378395chr4_102757158_-ncRNA_intronic
CAediting_378396chr4_102757201_-ncRNA_intronic
CAediting_378397chr4_102757229_-ncRNA_intronic
CAediting_378398chr4_102758619_-ncRNA_intronic
CAediting_378399chr4_102758640_-ncRNA_intronic
CAediting_378400chr4_102758668_-ncRNA_intronic
CAediting_378401chr4_102758675_-ncRNA_intronic
CAediting_378402chr4_102758687_-ncRNA_intronic
CAediting_378403chr4_102758707_-ncRNA_intronic
CAediting_378404chr4_102758711_-ncRNA_intronic
CAediting_378405chr4_102758713_-ncRNA_intronic
CAediting_378406chr4_102758720_-ncRNA_intronic
CAediting_378407chr4_102758725_-ncRNA_intronic
CAediting_378408chr4_102758796_-ncRNA_intronic
CAediting_378409chr4_102758813_-ncRNA_intronic
CAediting_378410chr4_102759259_-ncRNA_intronic
CAediting_378411chr4_102759260_-ncRNA_intronic
CAediting_378412chr4_102759265_-ncRNA_intronic
CAediting_378413chr4_102759268_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_378282chr4_102654179_-Simple_repeatSimple_repeat(CTTC)n
CAediting_378283chr4_102654199_-Simple_repeatSimple_repeat(CTTC)n
CAediting_378284chr4_102691524_-SINEAluAluJr
CAediting_378285chr4_102691549_-SINEAluAluJr
CAediting_378286chr4_102691552_-SINEAluAluJr
CAediting_378287chr4_102691584_-SINEAluAluJr
CAediting_378288chr4_102691588_-SINEAluAluJr
CAediting_378289chr4_102691598_-SINEAluAluJr
CAediting_378290chr4_102691603_-SINEAluAluJr
CAediting_378291chr4_102691614_-SINEAluAluJr
CAediting_378292chr4_102691617_-SINEAluAluJr
CAediting_378293chr4_102691621_-SINEAluAluJr
CAediting_378294chr4_102691627_-SINEAluAluJr
CAediting_378295chr4_102691628_-SINEAluAluJr
CAediting_378296chr4_102691630_-SINEAluAluJr
CAediting_378297chr4_102691644_-SINEAluAluJr
CAediting_378298chr4_102691665_-SINEAluAluJr
CAediting_378299chr4_102691669_-SINEAluAluJr
CAediting_378300chr4_102691672_-SINEAluAluJr
CAediting_378301chr4_102691677_-SINEAluAluJr
CAediting_378302chr4_102691678_-SINEAluAluJr
CAediting_378303chr4_102691690_-SINEAluAluJr
CAediting_378304chr4_102691696_-SINEAluAluJr
CAediting_378305chr4_102691708_-SINEAluAluJr
CAediting_378306chr4_102691720_-SINEAluAluJr
CAediting_378307chr4_102691727_-SINEAluAluJr
CAediting_378308chr4_102691783_-SINEAluAluJr
CAediting_378309chr4_102696179_-SINEAluAluJr
CAediting_378310chr4_102703165_-SINEAluAluJr
CAediting_378311chr4_102703228_-SINEAluAluJr
CAediting_378312chr4_102703957_-SINEAluAluSc8
CAediting_378313chr4_102704309_-SINEAluAluJr
CAediting_378314chr4_102704342_-SINEAluAluJr
CAediting_378315chr4_102704345_-SINEAluAluJr
CAediting_378316chr4_102704346_-SINEAluAluJr
CAediting_378317chr4_102704347_-SINEAluAluJr
CAediting_378318chr4_102704348_-SINEAluAluJr
CAediting_378319chr4_102704352_-SINEAluAluJr
CAediting_378320chr4_102704358_-SINEAluAluJr
CAediting_378321chr4_102704361_-SINEAluAluJr
CAediting_378322chr4_102704420_-SINEAluAluJr
CAediting_378323chr4_102712580_-SINEAluAluJb
CAediting_378324chr4_102712611_-SINEAluAluJb
CAediting_378325chr4_102712627_-SINEAluAluJb
CAediting_378326chr4_102712634_-SINEAluAluJb
CAediting_378327chr4_102712647_-SINEAluAluJb
CAediting_378328chr4_102712657_-SINEAluAluJb
CAediting_378329chr4_102712683_-SINEAluAluJb
CAediting_378330chr4_102712692_-SINEAluAluJb
CAediting_378331chr4_102712694_-SINEAluAluJb
CAediting_378332chr4_102712695_-SINEAluAluJb
CAediting_378333chr4_102712703_-SINEAluAluJb
CAediting_378334chr4_102712723_-SINEAluAluJb
CAediting_378335chr4_102712725_-SINEAluAluJb
CAediting_378336chr4_102712749_-SINEAluAluJb
CAediting_378337chr4_102712778_-SINEAluAluJb
CAediting_378338chr4_102712780_-SINEAluAluJb
CAediting_378339chr4_102713643_-SINEAluAluSq
CAediting_378340chr4_102713705_-SINEAluAluSq
CAediting_378341chr4_102713784_-SINEAluAluSq
CAediting_378342chr4_102716197_-SINEAluAluSp
CAediting_378343chr4_102716209_-SINEAluAluSp
CAediting_378344chr4_102717475_-SINEAluAluJb
CAediting_378345chr4_102717488_-SINEAluAluJb
CAediting_378346chr4_102717489_-SINEAluAluJb
CAediting_378347chr4_102717493_-SINEAluAluJb
CAediting_378348chr4_102717536_-SINEAluAluJb
CAediting_378349chr4_102717550_-SINEAluAluJb
CAediting_378350chr4_102717589_-SINEAluAluJb
CAediting_378351chr4_102717612_-SINEAluAluJb
CAediting_378352chr4_102717613_-SINEAluAluJb
CAediting_378353chr4_102717621_-SINEAluAluJb
CAediting_378354chr4_102717640_-SINEAluAluJb
CAediting_378355chr4_102721283_-SINEAluAluSx
CAediting_378356chr4_102721807_-SINEAluAluJb
CAediting_378357chr4_102727050_-SINEAluAluSz
CAediting_378360chr4_102731962_-SINEAluAluSq2
CAediting_378361chr4_102732135_-SINEAluAluSq2
CAediting_378362chr4_102733462_-SINEAluAluJo
CAediting_378363chr4_102733469_-SINEAluAluJo
CAediting_378364chr4_102733478_-SINEAluAluJo
CAediting_378365chr4_102733486_-SINEAluAluJo
CAediting_378366chr4_102733492_-SINEAluAluJo
CAediting_378367chr4_102733521_-SINEAluAluJo
CAediting_378368chr4_102733529_-SINEAluAluJo
CAediting_378369chr4_102733607_-SINEAluAluJo
CAediting_378370chr4_102733633_-SINEAluAluJo
CAediting_378371chr4_102733634_-SINEAluAluJo
CAediting_378372chr4_102750791_-SINEAluAluJo
CAediting_378373chr4_102750797_-SINEAluAluJo
CAediting_378374chr4_102750801_-SINEAluAluJo
CAediting_378375chr4_102750804_-SINEAluAluJo
CAediting_378376chr4_102750805_-SINEAluAluJo
CAediting_378377chr4_102750830_-SINEAluAluJo
CAediting_378378chr4_102750844_-SINEAluAluJo
CAediting_378379chr4_102750907_-SINEAluAluJo
CAediting_378380chr4_102753838_-SINEAluAluSx
CAediting_378381chr4_102753853_-SINEAluAluSx
CAediting_378382chr4_102753861_-SINEAluAluSx
CAediting_378383chr4_102753862_-SINEAluAluSx
CAediting_378384chr4_102753871_-SINEAluAluSx
CAediting_378385chr4_102753890_-SINEAluAluSx
CAediting_378386chr4_102753891_-SINEAluAluSx
CAediting_378387chr4_102753903_-SINEAluAluSx
CAediting_378388chr4_102753921_-SINEAluAluSx
CAediting_378389chr4_102753922_-SINEAluAluSx
CAediting_378390chr4_102753928_-SINEAluAluSx
CAediting_378391chr4_102753942_-SINEAluAluSx
CAediting_378392chr4_102753966_-SINEAluAluSx
CAediting_378393chr4_102753995_-SINEAluAluSx
CAediting_378394chr4_102757157_-SINEAluAluSp
CAediting_378395chr4_102757158_-SINEAluAluSp
CAediting_378396chr4_102757201_-SINEAluAluSp
CAediting_378397chr4_102757229_-SINEAluAluSp
CAediting_378398chr4_102758619_-SINEAluAluJb
CAediting_378399chr4_102758640_-SINEAluAluJb
CAediting_378400chr4_102758668_-SINEAluAluJb
CAediting_378401chr4_102758675_-SINEAluAluJb
CAediting_378402chr4_102758687_-SINEAluAluJb
CAediting_378403chr4_102758707_-SINEAluAluJb
CAediting_378404chr4_102758711_-SINEAluAluJb
CAediting_378405chr4_102758713_-SINEAluAluJb
CAediting_378406chr4_102758720_-SINEAluAluJb
CAediting_378407chr4_102758725_-SINEAluAluJb
CAediting_378408chr4_102758796_-SINEAluAluJb
CAediting_378409chr4_102758813_-SINEAluAluJb
CAediting_378410chr4_102759259_-SINEAluAluJo
CAediting_378411chr4_102759260_-SINEAluAluJo
CAediting_378412chr4_102759265_-SINEAluAluJo
CAediting_378413chr4_102759268_-SINEAluAluJo

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RNA A-to-I editing events in the alternative splicing sites for MANBA

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_378393chr4_102753995_-102753993:1027540153SS1+0iTTTTTTTTTTTTTGAGACAGAGT3.01TTTTTTTTTTTTTGAGACAGGGT4.19
MEX_2CAediting_378393chr4_102753995_-102753993:1027540153SS1+0iTTTTTTTTTTTTTGAGACAGAGT3.01TTTTTTTTTTTTTGAGACAGGGT4.19

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000109323.7.MANBA.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000109323.7.MANBA.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MANBA

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for MANBA

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for MANBA

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_378380chr4_102753838_-ENSG00000109323.7ENST00000511813hsa-miR-10397-5p1027538371027538437mer-m8102753836102753857148.00-22.81
CAediting_378382chr4_102753861_-ENSG00000109323.7ENST00000511813hsa-miR-1288-3p1027538581027538647mer-m8102753857102753878160.00-29.68
CAediting_378382chr4_102753861_-ENSG00000109323.7ENST00000511813hsa-miR-5002-3p1027538591027538657mer-m8102753858102753879150.00-13.71
CAediting_378385chr4_102753890_-ENSG00000109323.7ENST00000511813hsa-miR-42931027538871027538937mer-m8102753886102753903144.00-18.90
CAediting_378385chr4_102753890_-ENSG00000109323.7ENST00000511813hsa-miR-6849-3p1027538851027538917mer-m8102753884102753906151.00-20.95
CAediting_378381chr4_102753853_-ENSG00000109323.7ENST00000511813hsa-miR-47671027538521027538587mer-m8102753851102753876147.00-24.02
CAediting_378383chr4_102753862_-ENSG00000109323.7ENST00000511813hsa-miR-127-3p1027538571027538626mer102753856102753876142.00-32.11
CAediting_378383chr4_102753862_-ENSG00000109323.7ENST00000511813hsa-miR-60781027538611027538688mer-1a102753861102753880156.00-21.68
CAediting_378384chr4_102753871_-ENSG00000109323.7ENST00000511813hsa-miR-6840-3p1027538701027538767mer-m8102753869102753890147.00-22.99
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-1247-3p1027539261027539327mer-m8102753925102753947160.00-25.99
CAediting_378387chr4_102753903_-ENSG00000109323.7ENST00000511813hsa-miR-42851027539001027539067mer-m8102753899102753916148.00-20.92
CAediting_378388chr4_102753921_-ENSG00000109323.7ENST00000511813hsa-miR-60781027539171027539248mer-1a102753917102753935149.00-21.50

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_378381chr4_102753853_-ENSG00000109323.7ENST00000511813hsa-miR-1228-5p1027538531027538597mer-m8102753852102753872141-25.27
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-30b-3p1027539281027539347mer-m8102753927102753948152-23.02
CAediting_378384chr4_102753871_-ENSG00000109323.7ENST00000511813hsa-miR-36701027538661027538738mer-1a102753866102753889140-11.96
CAediting_378384chr4_102753871_-ENSG00000109323.7ENST00000511813hsa-miR-36701027538661027538738mer-1a102753866102753889140-11.96
CAediting_378384chr4_102753871_-ENSG00000109323.7ENST00000511813hsa-miR-36701027538661027538738mer-1a102753866102753889140-11.96
CAediting_378384chr4_102753871_-ENSG00000109323.7ENST00000511813hsa-miR-36701027538661027538738mer-1a102753866102753889140-11.96
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-3689a-3p1027539281027539347mer-m8102753927102753950150-24.51
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-3689b-3p1027539281027539347mer-m8102753927102753947154-24.3
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-3689c1027539281027539347mer-m8102753927102753947154-24.3
CAediting_378384chr4_102753871_-ENSG00000109323.7ENST00000511813hsa-miR-3934-3p1027538691027538757mer-m8102753868102753894145-22.86
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-490-3p1027539241027539307mer-m8102753923102753946150-18.9
CAediting_378381chr4_102753853_-ENSG00000109323.7ENST00000511813hsa-miR-541-3p1027538511027538577mer-m8102753850102753871147-21.12
CAediting_378381chr4_102753853_-ENSG00000109323.7ENST00000511813hsa-miR-61341027538491027538557mer-m8102753848102753866154-21.52
CAediting_378381chr4_102753853_-ENSG00000109323.7ENST00000511813hsa-miR-654-5p1027538511027538577mer-m8102753850102753871142-17.51
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-6779-5p1027539281027539347mer-m8102753927102753947144-23.81
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-6780a-5p1027539281027539347mer-m8102753927102753951155-23.92
CAediting_378390chr4_102753928_-ENSG00000109323.7ENST00000511813hsa-miR-6852-5p1027539261027539316mer102753925102753945141-20.96

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MANBA

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000511813.1nonsense_mediated_decaySoverviewSoverview
ENST00000507358.1retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_378380ENST00000511813.1chr4_102753838_--216.90-217.20-234.00
CAediting_378381ENST00000511813.1chr4_102753853_--217.20-217.20-234.00
CAediting_378382ENST00000511813.1chr4_102753861_--217.10-217.20-234.00
CAediting_378383ENST00000511813.1chr4_102753862_--221.10-217.20-234.00
CAediting_378384ENST00000511813.1chr4_102753871_--219.80-217.20-234.00
CAediting_378385ENST00000511813.1chr4_102753890_--219.00-217.20-234.00
CAediting_378386ENST00000511813.1chr4_102753891_--219.10-217.20-234.00
CAediting_378387ENST00000511813.1chr4_102753903_--217.50-217.20-234.00
CAediting_378388ENST00000511813.1chr4_102753921_--218.70-217.20-234.00
CAediting_378389ENST00000511813.1chr4_102753922_--221.60-217.20-234.00
CAediting_378390ENST00000511813.1chr4_102753928_--216.50-217.20-234.00
CAediting_378391ENST00000511813.1chr4_102753942_--216.50-217.20-234.00
CAediting_378392ENST00000511813.1chr4_102753966_--220.40-217.20-234.00
CAediting_378393ENST00000511813.1chr4_102753995_--216.80-217.20-234.00
CAediting_378380ENST00000507358.1chr4_102753838_--211.20-210.30-229.90
CAediting_378381ENST00000507358.1chr4_102753853_--210.30-210.30-229.90
CAediting_378382ENST00000507358.1chr4_102753861_--210.80-210.30-229.90
CAediting_378383ENST00000507358.1chr4_102753862_--213.50-210.30-229.90
CAediting_378384ENST00000507358.1chr4_102753871_--215.10-210.30-229.90
CAediting_378385ENST00000507358.1chr4_102753890_--214.30-210.30-229.90
CAediting_378386ENST00000507358.1chr4_102753891_--213.20-210.30-229.90
CAediting_378387ENST00000507358.1chr4_102753903_--211.70-210.30-229.90
CAediting_378388ENST00000507358.1chr4_102753921_--215.40-210.30-229.90
CAediting_378389ENST00000507358.1chr4_102753922_--214.70-210.30-229.90
CAediting_378390ENST00000507358.1chr4_102753928_--210.40-210.30-229.90
CAediting_378391ENST00000507358.1chr4_102753942_--209.10-210.30-229.90
CAediting_378392ENST00000507358.1chr4_102753966_--216.10-210.30-229.90
CAediting_378393ENST00000507358.1chr4_102753995_--210.00-210.30-229.90

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Relation with ADAR for MANBA

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for MANBA

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for MANBA

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for MANBA

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MANBA

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
MANBAC4048196beta-Mannosidosis8CTD_human;GENOMICS_ENGLAND;UNIPROT
MANBAC2931893Lysosomal beta-mannosidase deficiency1ORPHANET