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Editing gene: ASIC1 (CAeditome ID:41)

Gene summary for ASIC1

Gene summary

Gene information	Gene symbol	ASIC1
	Gene ID	41
	Gene name	acid sensing ion channel subunit 1
	Synonyms	ACCN2\|ASIC\|BNaC2
	Cytomap	12q13.12
	Type of gene	protein-coding
	Description	acid-sensing ion channel 1Cation channel, amiloride-sensitive, neuronal, 2acid sensing (proton gated) ion channel 1acid-sensing ion channel 1a proteinamiloride-sensitive cation channel 2, neuronalbrain sodium channel 2
	Modification date	20210518
	UniProtAcc	P78348
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
ASIC1	GO:0044736	Acid-sensing ion channel 1	22760635
ASIC1	GO:0035725	Acid-sensing ion channel 1	22760635
ASIC1	GO:0071467	Acid-sensing ion channel 1	22760635
ASIC1	GO:0005794	Acid-sensing ion channel 1	0000052
ASIC1	GO:0005886	Acid-sensing ion channel 1	0000052

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RNA A-to-I events for ASIC1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000110881.10

RNA A-to-I editing events in Cancer.

CAediting_886260(50062468, +), CAediting_886261(50062472, +), CAediting_886262(50067681, +), CAediting_886263(50072254, +), CAediting_886264(50076212, +), CAediting_886265(50076346, +), CAediting_886266(50076347, +), CAediting_886267(50079647, +), CAediting_886268(50079692, +), CAediting_886269(50079706, +), CAediting_886270(50079708, +), CAediting_886271(50079715, +), CAediting_886272(50079726, +), CAediting_886273(50081596, +), CAediting_886274(50081597, +), CAediting_886275(50081604, +), CAediting_886276(50081622, +), CAediting_886277(50081633, +), CAediting_886278(50081671, +), CAediting_886279(50081672, +), CAediting_886280(50081701, +), CAediting_886281(50082006, +),

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RNA editing positional annotations for ASIC1 using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_886273	chr12_50081596_+	nonsynonymous SNV	ENST00000228468.7	c.A1672G	p.N558D	D	D	N
CAediting_886273	chr12_50081596_+	nonsynonymous SNV	ENST00000447966.5	c.A1534G	p.N512D	D	D	N
CAediting_886273	chr12_50081596_+	nonsynonymous SNV	ENST00000552438.4	c.A1636G	p.N546D	D	D	N
CAediting_886274	chr12_50081597_+	nonsynonymous SNV	ENST00000228468.7	c.A1673G	p.N558S	T	P	N
CAediting_886274	chr12_50081597_+	nonsynonymous SNV	ENST00000447966.5	c.A1535G	p.N512S	T	P	N
CAediting_886274	chr12_50081597_+	nonsynonymous SNV	ENST00000552438.4	c.A1637G	p.N546S	T	P	N
CAediting_886277	chr12_50081633_+	nonsynonymous SNV	ENST00000228468.7	c.A1709G	p.E570G	D	D	D
CAediting_886277	chr12_50081633_+	nonsynonymous SNV	ENST00000447966.5	c.A1571G	p.E524G	D	D	D
CAediting_886277	chr12_50081633_+	nonsynonymous SNV	ENST00000552438.4	c.A1673G	p.E558G	D	D	D

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_886260	chr12_50062468_+	intronic
CAediting_886261	chr12_50062472_+	intronic
CAediting_886262	chr12_50067681_+	intronic
CAediting_886263	chr12_50072254_+	ncRNA_intronic
CAediting_886264	chr12_50076212_+	ncRNA_intronic
CAediting_886265	chr12_50076346_+	ncRNA_intronic
CAediting_886266	chr12_50076347_+	ncRNA_intronic
CAediting_886267	chr12_50079647_+	ncRNA_intronic
CAediting_886268	chr12_50079692_+	ncRNA_intronic
CAediting_886269	chr12_50079706_+	ncRNA_intronic
CAediting_886270	chr12_50079708_+	ncRNA_intronic
CAediting_886271	chr12_50079715_+	ncRNA_intronic
CAediting_886272	chr12_50079726_+	ncRNA_intronic
CAediting_886273	chr12_50081596_+	exonic
CAediting_886274	chr12_50081597_+	exonic
CAediting_886275	chr12_50081604_+	exonic
CAediting_886276	chr12_50081622_+	exonic
CAediting_886277	chr12_50081633_+	exonic
CAediting_886278	chr12_50081671_+	UTR3
CAediting_886279	chr12_50081672_+	UTR3
CAediting_886280	chr12_50081701_+	UTR3
CAediting_886281	chr12_50082006_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_886262	chr12_50067681_+	SINE	Alu	AluSp
CAediting_886264	chr12_50076212_+	SINE	Alu	AluSx
CAediting_886265	chr12_50076346_+	SINE	Alu	AluSx
CAediting_886266	chr12_50076347_+	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for ASIC1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000110881.10.ASIC1.

Correlation between RNA A-to-I editing and PSI for ENSG00000110881.10.ASIC1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ASIC1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ASIC1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ASIC1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000228468	hsa-miR-4757-5p	50081669	50081675	7mer-m8	50081656	50081676	147.00	-27.14
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000228468	hsa-miR-6744-3p	50081669	50081675	7mer-m8	50081652	50081676	152.00	-23.80
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000228468	hsa-miR-6764-3p	50081666	50081672	7mer-m8	50081653	50081673	140.00	-17.12
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000228468	hsa-miR-6824-3p	50081666	50081672	7mer-m8	50081653	50081673	149.00	-17.47
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000447966	hsa-miR-4757-5p	50081669	50081675	7mer-m8	50081656	50081676	147.00	-27.14
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000447966	hsa-miR-6744-3p	50081669	50081675	7mer-m8	50081652	50081676	152.00	-23.80
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000447966	hsa-miR-6764-3p	50081666	50081672	7mer-m8	50081653	50081673	140.00	-17.12
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000447966	hsa-miR-6824-3p	50081666	50081672	7mer-m8	50081653	50081673	149.00	-17.47
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000550558	hsa-miR-4757-5p	50081669	50081675	7mer-m8	50081656	50081676	147.00	-27.14
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6744-3p	50081669	50081675	7mer-m8	50081652	50081676	152.00	-23.80
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6764-3p	50081666	50081672	7mer-m8	50081653	50081673	140.00	-17.12
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6824-3p	50081666	50081672	7mer-m8	50081653	50081673	149.00	-17.47
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000453327	hsa-miR-4757-5p	50081669	50081675	7mer-m8	50081656	50081676	147.00	-27.14
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000453327	hsa-miR-6744-3p	50081669	50081675	7mer-m8	50081652	50081676	152.00	-23.80
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000453327	hsa-miR-6764-3p	50081666	50081672	7mer-m8	50081653	50081673	140.00	-17.12
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000453327	hsa-miR-6824-3p	50081666	50081672	7mer-m8	50081653	50081673	149.00	-17.47
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552438	hsa-miR-4757-5p	50081669	50081675	7mer-m8	50081656	50081676	147.00	-27.14
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552438	hsa-miR-6744-3p	50081669	50081675	7mer-m8	50081652	50081676	152.00	-23.80
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552438	hsa-miR-6764-3p	50081666	50081672	7mer-m8	50081653	50081673	140.00	-17.12
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552438	hsa-miR-6824-3p	50081666	50081672	7mer-m8	50081653	50081673	149.00	-17.47
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552633	hsa-miR-4757-5p	50081669	50081675	7mer-m8	50081656	50081676	147.00	-27.14
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552633	hsa-miR-6744-3p	50081669	50081675	7mer-m8	50081652	50081676	152.00	-23.80
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552633	hsa-miR-6764-3p	50081666	50081672	7mer-m8	50081653	50081673	140.00	-17.12
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552633	hsa-miR-6824-3p	50081666	50081672	7mer-m8	50081653	50081673	149.00	-17.47
CAediting_886274	chr12_50081597_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6868-5p	50081590	50081596	7mer-m8	50081576	50081597	140.00	-15.23
CAediting_886274	chr12_50081597_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9851-5p	50081591	50081598	8mer-1a	50081577	50081598	162.00	-23.25
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-miR-1827	50081601	50081608	8mer-1a	50081591	50081608	151.00	-15.69
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-miR-449c-5p	50081601	50081606	6mer	50081583	50081607	144.00	-21.90
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6765-5p	50081603	50081608	6mer	50081583	50081609	142.00	-34.21
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6808-5p	50081600	50081606	7mer-m8	50081586	50081607	159.00	-19.74
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6893-5p	50081600	50081606	7mer-m8	50081586	50081607	153.00	-21.78
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-miR-940	50081600	50081606	7mer-m8	50081587	50081607	141.00	-14.71
CAediting_886276	chr12_50081622_+	ENSG00000110881.10	ENST00000550558	hsa-miR-10396a-3p	50081618	50081625	8mer-1a	50081605	50081625	155.00	-29.41
CAediting_886276	chr12_50081622_+	ENSG00000110881.10	ENST00000550558	hsa-miR-10396b-3p	50081618	50081625	8mer-1a	50081604	50081625	155.00	-29.44
CAediting_886276	chr12_50081622_+	ENSG00000110881.10	ENST00000550558	hsa-miR-5587-3p	50081617	50081623	7mer-m8	50081604	50081624	159.00	-26.98
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000228468	hsa-miR-6851-3p	50081669	50081675	7mer-m8	50081656	50081676	149.00	-15.61
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000447966	hsa-miR-6851-3p	50081669	50081675	7mer-m8	50081656	50081676	149.00	-15.61
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6851-3p	50081669	50081675	7mer-m8	50081656	50081676	149.00	-15.61
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000453327	hsa-miR-6851-3p	50081669	50081675	7mer-m8	50081656	50081676	149.00	-15.61
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552438	hsa-miR-6851-3p	50081669	50081675	7mer-m8	50081656	50081676	149.00	-15.61
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552633	hsa-miR-6851-3p	50081669	50081675	7mer-m8	50081656	50081676	149.00	-15.61
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000228468	hsa-miR-4757-5p	50082004	50082010	7mer-m8	50081986	50082011	159.00	-27.04
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000228468	hsa-miR-6744-3p	50082004	50082010	7mer-m8	50081989	50082011	146.00	-22.24
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000228468	hsa-miR-6764-3p	50082001	50082007	7mer-m8	50081988	50082008	141.00	-18.28
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000228468	hsa-miR-6824-3p	50082001	50082007	7mer-m8	50081984	50082008	143.00	-17.25
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000447966	hsa-miR-4757-5p	50082004	50082010	7mer-m8	50081986	50082011	159.00	-27.04
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000447966	hsa-miR-6744-3p	50082004	50082010	7mer-m8	50081989	50082011	146.00	-22.24
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000447966	hsa-miR-6764-3p	50082001	50082007	7mer-m8	50081988	50082008	141.00	-18.28
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000447966	hsa-miR-6824-3p	50082001	50082007	7mer-m8	50081984	50082008	143.00	-17.25
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000550558	hsa-miR-4757-5p	50082004	50082010	7mer-m8	50081986	50082011	159.00	-27.04
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6744-3p	50082004	50082010	7mer-m8	50081989	50082011	146.00	-22.24
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6764-3p	50082001	50082007	7mer-m8	50081988	50082008	141.00	-18.28
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6824-3p	50082001	50082007	7mer-m8	50081984	50082008	143.00	-17.25
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000552438	hsa-miR-4757-5p	50082004	50082010	7mer-m8	50081986	50082011	159.00	-27.04
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000552438	hsa-miR-6744-3p	50082004	50082010	7mer-m8	50081989	50082011	146.00	-22.24
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000552438	hsa-miR-6764-3p	50082001	50082007	7mer-m8	50081988	50082008	141.00	-18.28
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000552438	hsa-miR-6824-3p	50082001	50082007	7mer-m8	50081984	50082008	143.00	-17.25

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000228468	hsa-miR-3142	50081670	50081677	8mer-1a	50081656	50081677	145	-15.54
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000228468	hsa-miR-659-3p	50081664	50081671	8mer-1a	50081650	50081671	152	-21.45
CAediting_886280	chr12_50081701_+	ENSG00000110881.10	ENST00000228468	hsa-miR-6795-3p	50081698	50081704	7mer-m8	50081684	50081705	154	-24.35
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000228468	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000447966	hsa-miR-3142	50081670	50081677	8mer-1a	50081656	50081677	145	-15.54
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000447966	hsa-miR-659-3p	50081664	50081671	8mer-1a	50081650	50081671	152	-21.45
CAediting_886280	chr12_50081701_+	ENSG00000110881.10	ENST00000447966	hsa-miR-6795-3p	50081698	50081704	7mer-m8	50081684	50081705	154	-24.35
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000447966	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-let-7f-5p	50081601	50081608	8mer-1a	50081587	50081608	151	-16.6
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-let-7f-5p	50081601	50081608	8mer-1a	50081587	50081608	151	-16.6
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-let-7i-5p	50081601	50081608	8mer-1a	50081586	50081608	155	-18.13
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000550558	hsa-miR-3142	50081670	50081677	8mer-1a	50081656	50081677	145	-15.54
CAediting_886276	chr12_50081622_+	ENSG00000110881.10	ENST00000550558	hsa-miR-3181	50081615	50081621	7mer-m8	50081604	50081622	140	-22.66
CAediting_886275	chr12_50081604_+	ENSG00000110881.10	ENST00000550558	hsa-miR-4500	50081601	50081608	8mer-1a	50081591	50081608	148	-13.66
CAediting_886273	chr12_50081596_+	ENSG00000110881.10	ENST00000550558	hsa-miR-4781-3p	50081593	50081599	7mer-m8	50081579	50081600	146	-11.21
CAediting_886274	chr12_50081597_+	ENSG00000110881.10	ENST00000550558	hsa-miR-4781-3p	50081593	50081599	7mer-m8	50081579	50081600	146	-11.21
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000550558	hsa-miR-659-3p	50081664	50081671	8mer-1a	50081650	50081671	152	-21.45
CAediting_886280	chr12_50081701_+	ENSG00000110881.10	ENST00000550558	hsa-miR-6795-3p	50081698	50081704	7mer-m8	50081684	50081705	154	-24.35
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000550558	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000453327	hsa-miR-3142	50081670	50081677	8mer-1a	50081656	50081677	145	-15.54
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000453327	hsa-miR-659-3p	50081664	50081671	8mer-1a	50081650	50081671	152	-21.45
CAediting_886280	chr12_50081701_+	ENSG00000110881.10	ENST00000453327	hsa-miR-6795-3p	50081698	50081704	7mer-m8	50081684	50081705	154	-24.35
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000453327	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000453327	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000453327	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000453327	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000453327	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000453327	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552438	hsa-miR-3142	50081670	50081677	8mer-1a	50081656	50081677	145	-15.54
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552438	hsa-miR-659-3p	50081664	50081671	8mer-1a	50081650	50081671	152	-21.45
CAediting_886280	chr12_50081701_+	ENSG00000110881.10	ENST00000552438	hsa-miR-6795-3p	50081698	50081704	7mer-m8	50081684	50081705	154	-24.35
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886281	chr12_50082006_+	ENSG00000110881.10	ENST00000552438	hsa-miR-9-5p	50082001	50082007	7mer-m8	50081987	50082008	150	-13.38
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552633	hsa-miR-3142	50081670	50081677	8mer-1a	50081656	50081677	145	-15.54
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552633	hsa-miR-659-3p	50081664	50081671	8mer-1a	50081650	50081671	152	-21.45
CAediting_886280	chr12_50081701_+	ENSG00000110881.10	ENST00000552633	hsa-miR-6795-3p	50081698	50081704	7mer-m8	50081684	50081705	154	-24.35
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552633	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552633	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552633	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552633	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886278	chr12_50081671_+	ENSG00000110881.10	ENST00000552633	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53
CAediting_886279	chr12_50081672_+	ENSG00000110881.10	ENST00000552633	hsa-miR-9-5p	50081666	50081672	7mer-m8	50081650	50081673	150	-17.53

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000110881.10	ENST00000228468	hsa-miR-605-3p	50082939	50082945	7mer-m8	50082927	50082946	154	-18
CAediting_748296	chr10_51299626_+	ENSG00000110881.10	ENST00000447966	hsa-miR-605-3p	50082939	50082945	7mer-m8	50082927	50082946	154	-18
CAediting_688080	chr9_63819626_+	ENSG00000110881.10	ENST00000550558	hsa-miR-4477b	50080532	50080538	7mer-m8	50080518	50080539	153	-12.37
CAediting_748296	chr10_51299626_+	ENSG00000110881.10	ENST00000550558	hsa-miR-605-3p	50082939	50082945	7mer-m8	50082927	50082946	154	-18
CAediting_748296	chr10_51299626_+	ENSG00000110881.10	ENST00000552438	hsa-miR-605-3p	50082939	50082945	7mer-m8	50082927	50082946	154	-18
CAediting_1229414	chr17_67471546_+	ENSG00000110881.10	ENST00000228468	hsa-miR-548aa	50083384	50083390	7mer-m8	50083368	50083391	142	-11.93
CAediting_1368054	chr19_46709310_-	ENSG00000110881.10	ENST00000228468	hsa-miR-320e	50082388	50082395	8mer-1a	50082376	50082395	144	-17.51
CAediting_86358	chr1_109598906_+	ENSG00000110881.10	ENST00000228468	hsa-miR-197-5p	50082609	50082615	7mer-m8	50082590	50082616	171	-35.18
CAediting_77128	chr1_85133844_+	ENSG00000110881.10	ENST00000228468	hsa-miR-4423-3p	50083149	50083155	7mer-m8	50083136	50083156	161	-18.28
CAediting_604450	chr7_133034877_-	ENSG00000110881.10	ENST00000228468	hsa-miR-3654	50082386	50082392	7mer-m8	50082377	50082393	148	-17.37
CAediting_1229414	chr17_67471546_+	ENSG00000110881.10	ENST00000447966	hsa-miR-548aa	50083384	50083390	7mer-m8	50083368	50083391	142	-11.93
CAediting_1368054	chr19_46709310_-	ENSG00000110881.10	ENST00000447966	hsa-miR-320e	50082388	50082395	8mer-1a	50082376	50082395	144	-17.51
CAediting_86358	chr1_109598906_+	ENSG00000110881.10	ENST00000447966	hsa-miR-197-5p	50082609	50082615	7mer-m8	50082590	50082616	171	-35.18
CAediting_77128	chr1_85133844_+	ENSG00000110881.10	ENST00000447966	hsa-miR-4423-3p	50083149	50083155	7mer-m8	50083136	50083156	161	-18.28
CAediting_604450	chr7_133034877_-	ENSG00000110881.10	ENST00000447966	hsa-miR-3654	50082386	50082392	7mer-m8	50082377	50082393	148	-17.37
CAediting_573001	chr7_92204086_-	ENSG00000110881.10	ENST00000550558	hsa-miR-1285-5p	50078523	50078529	7mer-m8	50078509	50078530	151	-18.53
CAediting_524911	chr7_5495852_-	ENSG00000110881.10	ENST00000550558	hsa-miR-589-3p	50078972	50078978	7mer-m8	50078953	50078979	146	-21.57
CAediting_1229414	chr17_67471546_+	ENSG00000110881.10	ENST00000550558	hsa-miR-548aa	50083384	50083390	7mer-m8	50083368	50083391	142	-11.93
CAediting_1368054	chr19_46709310_-	ENSG00000110881.10	ENST00000550558	hsa-miR-320e	50082388	50082395	8mer-1a	50082376	50082395	144	-17.51
CAediting_86358	chr1_109598906_+	ENSG00000110881.10	ENST00000550558	hsa-miR-197-5p	50082609	50082615	7mer-m8	50082590	50082616	171	-35.18
CAediting_77128	chr1_85133844_+	ENSG00000110881.10	ENST00000550558	hsa-miR-4423-3p	50083149	50083155	7mer-m8	50083136	50083156	161	-18.28
CAediting_604450	chr7_133034877_-	ENSG00000110881.10	ENST00000550558	hsa-miR-3654	50082386	50082392	7mer-m8	50082377	50082393	148	-17.37
CAediting_1368054	chr19_46709310_-	ENSG00000110881.10	ENST00000552438	hsa-miR-320e	50082388	50082395	8mer-1a	50082376	50082395	144	-17.51
CAediting_86358	chr1_109598906_+	ENSG00000110881.10	ENST00000552438	hsa-miR-197-5p	50082609	50082615	7mer-m8	50082590	50082616	171	-35.18
CAediting_77128	chr1_85133844_+	ENSG00000110881.10	ENST00000552438	hsa-miR-4423-3p	50083149	50083155	7mer-m8	50083136	50083156	161	-18.28
CAediting_604450	chr7_133034877_-	ENSG00000110881.10	ENST00000552438	hsa-miR-3654	50082386	50082392	7mer-m8	50082377	50082393	148	-17.37
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000228468	hsa-miR-6891-5p	50081716	50081723	8mer-1a	50081705	50081723	157	-30.53
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000447966	hsa-miR-6891-5p	50081716	50081723	8mer-1a	50081705	50081723	157	-30.53
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000550558	hsa-miR-6891-5p	50081716	50081723	8mer-1a	50081705	50081723	157	-30.53
CAediting_1524209	chrX_134546392_-	ENSG00000110881.10	ENST00000550558	hsa-miR-503-5p	50081588	50081595	8mer-1a	50081573	50081595	144	-23.67
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000453327	hsa-miR-6891-5p	50081716	50081723	8mer-1a	50081705	50081723	157	-30.53
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000552438	hsa-miR-6891-5p	50081716	50081723	8mer-1a	50081705	50081723	157	-30.53
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000552633	hsa-miR-6891-5p	50081716	50081723	8mer-1a	50081705	50081723	157	-30.53

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_846604	chr11_93733708_-	ENSG00000110881.10	ENST00000228468	hsa-miR-1304-3p	50082016	50082022	7mer-m8	50082002	50082023	140	-16.95
CAediting_77128	chr1_85133844_+	ENSG00000110881.10	ENST00000228468	hsa-miR-4423-3p	50082411	50082418	8mer-1a	50082398	50082418	142	-12.96
CAediting_1054808	chr15_66496985_-	ENSG00000110881.10	ENST00000228468	hsa-miR-4512	50082006	50082012	7mer-m8	50081992	50082013	140	-14.82
CAediting_1054808	chr15_66496985_-	ENSG00000110881.10	ENST00000228468	hsa-miR-4512	50082440	50082446	7mer-m8	50082426	50082447	145	-16.71
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000228468	hsa-miR-6891-5p	50083138	50083144	7mer-m8	50083127	50083145	143	-20.5
CAediting_846604	chr11_93733708_-	ENSG00000110881.10	ENST00000447966	hsa-miR-1304-3p	50082016	50082022	7mer-m8	50082002	50082023	140	-16.95
CAediting_77128	chr1_85133844_+	ENSG00000110881.10	ENST00000447966	hsa-miR-4423-3p	50082411	50082418	8mer-1a	50082398	50082418	142	-12.96
CAediting_1054808	chr15_66496985_-	ENSG00000110881.10	ENST00000447966	hsa-miR-4512	50082006	50082012	7mer-m8	50081992	50082013	140	-14.82
CAediting_1054808	chr15_66496985_-	ENSG00000110881.10	ENST00000447966	hsa-miR-4512	50082440	50082446	7mer-m8	50082426	50082447	145	-16.71
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000447966	hsa-miR-6891-5p	50083138	50083144	7mer-m8	50083127	50083145	143	-20.5
CAediting_846604	chr11_93733708_-	ENSG00000110881.10	ENST00000550558	hsa-miR-1304-3p	50082016	50082022	7mer-m8	50082002	50082023	140	-16.95
CAediting_77128	chr1_85133844_+	ENSG00000110881.10	ENST00000550558	hsa-miR-4423-3p	50082411	50082418	8mer-1a	50082398	50082418	142	-12.96
CAediting_1054808	chr15_66496985_-	ENSG00000110881.10	ENST00000550558	hsa-miR-4512	50082006	50082012	7mer-m8	50081992	50082013	140	-14.82
CAediting_1054808	chr15_66496985_-	ENSG00000110881.10	ENST00000550558	hsa-miR-4512	50082440	50082446	7mer-m8	50082426	50082447	145	-16.71
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000550558	hsa-miR-6891-5p	50083138	50083144	7mer-m8	50083127	50083145	143	-20.5
CAediting_846604	chr11_93733708_-	ENSG00000110881.10	ENST00000552438	hsa-miR-1304-3p	50082016	50082022	7mer-m8	50082002	50082023	140	-16.95
CAediting_77128	chr1_85133844_+	ENSG00000110881.10	ENST00000552438	hsa-miR-4423-3p	50082411	50082418	8mer-1a	50082398	50082418	142	-12.96
CAediting_1054808	chr15_66496985_-	ENSG00000110881.10	ENST00000552438	hsa-miR-4512	50082006	50082012	7mer-m8	50081992	50082013	140	-14.82
CAediting_1054808	chr15_66496985_-	ENSG00000110881.10	ENST00000552438	hsa-miR-4512	50082440	50082446	7mer-m8	50082426	50082447	145	-16.71
CAediting_468389	chr6_31355314_-	ENSG00000110881.10	ENST00000552438	hsa-miR-6891-5p	50083138	50083144	7mer-m8	50083127	50083145	143	-20.5

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for ASIC1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for ASIC1

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

Top

Relation with cancer stages for ASIC1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for ASIC1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ASIC1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
ASIC1	P78348	DB00594	Amiloride	Acid-sensing ion channel 1	SmallMoleculeDrug	approved

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RelatedDiseases for ASIC1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
ASIC1	C0007786	Brain Ischemia	1	CTD_human
ASIC1	C0021368	Inflammation	1	CTD_human
ASIC1	C0917798	Cerebral Ischemia	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene