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Editing gene: SMAD9 (CAeditome ID:4093)

Gene summary for SMAD9

Gene summary

Gene information	Gene symbol	SMAD9
	Gene ID	4093
	Gene name	SMAD family member 9
	Synonyms	MADH6\|MADH9\|PPH2\|SMAD8\|SMAD8/9\|SMAD8A\|SMAD8B
	Cytomap	13q13.3
	Type of gene	protein-coding
	Description	mothers against decapentaplegic homolog 9MAD homolog 9Mothers against decapentaplegic, drosophila, homolog of, 9SMAD, mothers against DPP homolog 9
	Modification date	20210518
	UniProtAcc	O15198
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SMAD9	GO:0005654	Mothers against decapentaplegic homolog 9	0000052
SMAD9	GO:0005829	Mothers against decapentaplegic homolog 9	0000052

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RNA A-to-I events for SMAD9

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000120693.12

RNA A-to-I editing events in Cancer.

CAediting_958293(36845246, -), CAediting_958294(36845257, -), CAediting_958295(36845287, -), CAediting_958296(36845301, -), CAediting_958297(36845994, -), CAediting_958298(36846007, -), CAediting_958299(36846020, -), CAediting_958300(36846025, -), CAediting_958301(36846028, -), CAediting_958302(36846031, -), CAediting_958303(36846032, -), CAediting_958304(36846049, -), CAediting_958305(36846052, -), CAediting_958306(36846057, -), CAediting_958307(36846075, -), CAediting_958308(36846076, -), CAediting_958309(36846081, -), CAediting_958310(36846098, -), CAediting_958311(36846100, -), CAediting_958312(36846106, -), CAediting_958313(36846114, -), CAediting_958314(36846224, -), CAediting_958315(36846226, -), CAediting_958316(36846238, -), CAediting_958317(36846239, -), CAediting_958318(36846240, -), CAediting_958319(36846248, -), CAediting_958320(36846261, -), CAediting_958321(36846277, -), CAediting_958322(36846293, -), CAediting_958323(36846301, -), CAediting_958324(36846315, -), CAediting_958325(36846318, -), CAediting_958326(36846367, -), CAediting_958327(36846375, -), CAediting_958328(36846412, -), CAediting_958329(36846418, -), CAediting_958330(36846428, -), CAediting_958331(36846442, -), CAediting_958332(36846444, -), CAediting_958333(36846449, -), CAediting_958334(36846466, -), CAediting_958335(36850477, -), CAediting_958336(36850549, -), CAediting_958337(36853100, -), CAediting_958338(36853122, -), CAediting_958339(36853163, -), CAediting_958340(36853202, -), CAediting_958341(36853962, -), CAediting_958342(36869707, -), CAediting_958343(36878054, -), CAediting_958344(36879013, -), CAediting_958345(36900981, -), CAediting_958346(36900982, -), CAediting_958347(36901217, -), CAediting_958348(36901226, -), CAediting_958349(36901233, -), CAediting_958350(36901860, -), CAediting_958351(36903223, -), CAediting_958352(36903330, -), CAediting_958353(36907471, -), CAediting_958354(36907475, -), CAediting_958355(36907553, -), CAediting_958356(36907592, -), CAediting_958357(36907623, -), CAediting_958358(36907629, -),

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RNA editing positional annotations for SMAD9 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_958293	chr13_36845246_-	UTR3
CAediting_958294	chr13_36845257_-	UTR3
CAediting_958295	chr13_36845287_-	UTR3
CAediting_958296	chr13_36845301_-	UTR3
CAediting_958297	chr13_36845994_-	UTR3
CAediting_958298	chr13_36846007_-	UTR3
CAediting_958299	chr13_36846020_-	UTR3
CAediting_958300	chr13_36846025_-	UTR3
CAediting_958301	chr13_36846028_-	UTR3
CAediting_958302	chr13_36846031_-	UTR3
CAediting_958303	chr13_36846032_-	UTR3
CAediting_958304	chr13_36846049_-	UTR3
CAediting_958305	chr13_36846052_-	UTR3
CAediting_958306	chr13_36846057_-	UTR3
CAediting_958307	chr13_36846075_-	UTR3
CAediting_958308	chr13_36846076_-	UTR3
CAediting_958309	chr13_36846081_-	UTR3
CAediting_958310	chr13_36846098_-	UTR3
CAediting_958311	chr13_36846100_-	UTR3
CAediting_958312	chr13_36846106_-	UTR3
CAediting_958313	chr13_36846114_-	UTR3
CAediting_958314	chr13_36846224_-	UTR3
CAediting_958315	chr13_36846226_-	UTR3
CAediting_958316	chr13_36846238_-	UTR3
CAediting_958317	chr13_36846239_-	UTR3
CAediting_958318	chr13_36846240_-	UTR3
CAediting_958319	chr13_36846248_-	UTR3
CAediting_958320	chr13_36846261_-	UTR3
CAediting_958321	chr13_36846277_-	UTR3
CAediting_958322	chr13_36846293_-	UTR3
CAediting_958323	chr13_36846301_-	UTR3
CAediting_958324	chr13_36846315_-	UTR3
CAediting_958325	chr13_36846318_-	UTR3
CAediting_958326	chr13_36846367_-	UTR3
CAediting_958327	chr13_36846375_-	UTR3
CAediting_958328	chr13_36846412_-	UTR3
CAediting_958329	chr13_36846418_-	UTR3
CAediting_958330	chr13_36846428_-	UTR3
CAediting_958331	chr13_36846442_-	UTR3
CAediting_958332	chr13_36846444_-	UTR3
CAediting_958333	chr13_36846449_-	UTR3
CAediting_958334	chr13_36846466_-	UTR3
CAediting_958335	chr13_36850477_-	intronic
CAediting_958336	chr13_36850549_-	intronic
CAediting_958337	chr13_36853100_-	intronic
CAediting_958338	chr13_36853122_-	intronic
CAediting_958339	chr13_36853163_-	intronic
CAediting_958340	chr13_36853202_-	intronic
CAediting_958341	chr13_36853962_-	intronic
CAediting_958342	chr13_36869707_-	intronic
CAediting_958343	chr13_36878054_-	intronic
CAediting_958344	chr13_36879013_-	intronic
CAediting_958345	chr13_36900981_-	ncRNA_intronic
CAediting_958346	chr13_36900982_-	ncRNA_intronic
CAediting_958347	chr13_36901217_-	ncRNA_intronic
CAediting_958348	chr13_36901226_-	ncRNA_intronic
CAediting_958349	chr13_36901233_-	ncRNA_intronic
CAediting_958350	chr13_36901860_-	ncRNA_intronic
CAediting_958351	chr13_36903223_-	ncRNA_intronic
CAediting_958352	chr13_36903330_-	ncRNA_intronic
CAediting_958353	chr13_36907471_-	ncRNA_intronic
CAediting_958354	chr13_36907475_-	ncRNA_intronic
CAediting_958355	chr13_36907553_-	ncRNA_intronic
CAediting_958356	chr13_36907592_-	ncRNA_intronic
CAediting_958357	chr13_36907623_-	ncRNA_intronic
CAediting_958358	chr13_36907629_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_958297	chr13_36845994_-	SINE	Alu	FRAM
CAediting_958298	chr13_36846007_-	SINE	Alu	FRAM
CAediting_958299	chr13_36846020_-	SINE	Alu	FRAM
CAediting_958300	chr13_36846025_-	SINE	Alu	FRAM
CAediting_958301	chr13_36846028_-	SINE	Alu	FRAM
CAediting_958302	chr13_36846031_-	SINE	Alu	FRAM
CAediting_958303	chr13_36846032_-	SINE	Alu	FRAM
CAediting_958304	chr13_36846049_-	SINE	Alu	FRAM
CAediting_958305	chr13_36846052_-	SINE	Alu	FRAM
CAediting_958306	chr13_36846057_-	SINE	Alu	FRAM
CAediting_958307	chr13_36846075_-	SINE	Alu	FRAM
CAediting_958308	chr13_36846076_-	SINE	Alu	FRAM
CAediting_958309	chr13_36846081_-	SINE	Alu	FRAM
CAediting_958310	chr13_36846098_-	SINE	Alu	FRAM
CAediting_958311	chr13_36846100_-	SINE	Alu	FRAM
CAediting_958312	chr13_36846106_-	SINE	Alu	FRAM
CAediting_958313	chr13_36846114_-	SINE	Alu	FRAM
CAediting_958314	chr13_36846224_-	SINE	Alu	AluSc
CAediting_958315	chr13_36846226_-	SINE	Alu	AluSc
CAediting_958316	chr13_36846238_-	SINE	Alu	AluSc
CAediting_958317	chr13_36846239_-	SINE	Alu	AluSc
CAediting_958318	chr13_36846240_-	SINE	Alu	AluSc
CAediting_958319	chr13_36846248_-	SINE	Alu	AluSc
CAediting_958320	chr13_36846261_-	SINE	Alu	AluSc
CAediting_958321	chr13_36846277_-	SINE	Alu	AluSc
CAediting_958322	chr13_36846293_-	SINE	Alu	AluSc
CAediting_958323	chr13_36846301_-	SINE	Alu	AluSc
CAediting_958324	chr13_36846315_-	SINE	Alu	AluSc
CAediting_958325	chr13_36846318_-	SINE	Alu	AluSc
CAediting_958326	chr13_36846367_-	SINE	Alu	AluSc
CAediting_958327	chr13_36846375_-	SINE	Alu	AluSc
CAediting_958328	chr13_36846412_-	SINE	Alu	AluSc
CAediting_958329	chr13_36846418_-	SINE	Alu	AluSc
CAediting_958330	chr13_36846428_-	SINE	Alu	AluSc
CAediting_958331	chr13_36846442_-	SINE	Alu	AluSc
CAediting_958332	chr13_36846444_-	SINE	Alu	AluSc
CAediting_958333	chr13_36846449_-	SINE	Alu	AluSc
CAediting_958334	chr13_36846466_-	SINE	Alu	AluSc
CAediting_958335	chr13_36850477_-	SINE	Alu	AluSz
CAediting_958336	chr13_36850549_-	SINE	Alu	AluSz
CAediting_958337	chr13_36853100_-	SINE	Alu	AluSx4
CAediting_958338	chr13_36853122_-	SINE	Alu	AluSx4
CAediting_958339	chr13_36853163_-	SINE	Alu	AluSx4
CAediting_958340	chr13_36853202_-	SINE	Alu	AluSx4
CAediting_958341	chr13_36853962_-	SINE	Alu	AluSx1
CAediting_958342	chr13_36869707_-	SINE	Alu	AluSq2
CAediting_958345	chr13_36900981_-	LINE	L1	L1MB5
CAediting_958346	chr13_36900982_-	LINE	L1	L1MB5
CAediting_958347	chr13_36901217_-	LINE	L1	L1MB5
CAediting_958348	chr13_36901226_-	LINE	L1	L1MB5
CAediting_958349	chr13_36901233_-	LINE	L1	L1MB5
CAediting_958350	chr13_36901860_-	LINE	L1	L1MB5
CAediting_958351	chr13_36903223_-	SINE	Alu	AluSg
CAediting_958352	chr13_36903330_-	SINE	Alu	AluSg
CAediting_958353	chr13_36907471_-	SINE	Alu	AluJr
CAediting_958354	chr13_36907475_-	SINE	Alu	AluJr
CAediting_958355	chr13_36907553_-	SINE	Alu	AluJr
CAediting_958356	chr13_36907592_-	SINE	Alu	AluJr
CAediting_958357	chr13_36907623_-	SINE	Alu	AluJr
CAediting_958358	chr13_36907629_-	SINE	Alu	AluJr

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RNA A-to-I editing events in the alternative splicing sites for SMAD9

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000120693.12.SMAD9.

Correlation between RNA A-to-I editing and PSI for ENSG00000120693.12.SMAD9.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SMAD9

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

KIRC.CAediting_958311.ENSG00000120693.SMAD9.png
Soverview

THCA.CAediting_958305.ENSG00000120693.SMAD9.png
Soverview

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Protein coding region RNA A-to-I editings for SMAD9

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SMAD9

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_958298	chr13_36846007_-	ENSG00000120693.12	ENST00000379826	hsa-miR-1972	36846002	36846008	7mer-m8	36846001	36846022	146.00	-21.16
CAediting_958298	chr13_36846007_-	ENSG00000120693.12	ENST00000379826	hsa-miR-1972	36846002	36846008	7mer-m8	36846001	36846022	146.00	-21.16
CAediting_958310	chr13_36846098_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3619-3p	36846094	36846100	7mer-m8	36846093	36846114	140.00	-18.89
CAediting_958316	chr13_36846238_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3189-3p	36846237	36846243	7mer-m8	36846236	36846258	153.00	-24.98
CAediting_958316	chr13_36846238_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6813-3p	36846236	36846242	7mer-m8	36846235	36846255	140.00	-10.68
CAediting_958328	chr13_36846412_-	ENSG00000120693.12	ENST00000379826	hsa-miR-17-3p	36846412	36846418	7mer-m8	36846411	36846431	153.00	-18.02
CAediting_958328	chr13_36846412_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3929	36846409	36846414	6mer	36846408	36846432	140.00	-27.65
CAediting_958328	chr13_36846412_-	ENSG00000120693.12	ENST00000379826	hsa-miR-485-5p	36846408	36846414	7mer-m8	36846407	36846427	153.00	-19.66
CAediting_958328	chr13_36846412_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6884-5p	36846408	36846414	7mer-m8	36846407	36846429	146.00	-21.96
CAediting_958331	chr13_36846442_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3620-3p	36846439	36846445	7mer-m8	36846438	36846459	140.00	-16.46
CAediting_958331	chr13_36846442_-	ENSG00000120693.12	ENST00000379826	hsa-miR-500a-3p	36846437	36846442	6mer	36846436	36846457	140.00	-21.97
CAediting_958294	chr13_36845257_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3065-5p	36845254	36845260	7mer-m8	36845253	36845275	153.00	-12.56
CAediting_958294	chr13_36845257_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3529-3p	36845253	36845259	7mer-m8	36845252	36845273	155.00	-10.23
CAediting_958294	chr13_36845257_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3613-3p	36845257	36845263	7mer-m8	36845256	36845279	142.00	-4.44
CAediting_958297	chr13_36845994_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3664-5p	36845991	36845997	7mer-m8	36845990	36846012	151.00	-17.09
CAediting_958297	chr13_36845994_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6794-3p	36845989	36845995	7mer-m8	36845988	36846005	150.00	-15.95
CAediting_958301	chr13_36846028_-	ENSG00000120693.12	ENST00000379826	hsa-miR-27a-3p	36846025	36846031	7mer-m8	36846024	36846046	157.00	-22.98
CAediting_958301	chr13_36846028_-	ENSG00000120693.12	ENST00000379826	hsa-miR-27b-3p	36846025	36846031	7mer-m8	36846024	36846046	153.00	-18.77
CAediting_958302	chr13_36846031_-	ENSG00000120693.12	ENST00000379826	hsa-miR-7705	36846027	36846033	7mer-m8	36846026	36846045	149.00	-17.81
CAediting_958304	chr13_36846049_-	ENSG00000120693.12	ENST00000379826	hsa-miR-331-3p	36846048	36846054	7mer-m8	36846047	36846067	153.00	-24.88
CAediting_958304	chr13_36846049_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4292	36846049	36846055	7mer-m8	36846048	36846066	147.00	-28.03
CAediting_958304	chr13_36846049_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6771-3p	36846045	36846051	7mer-m8	36846044	36846064	150.00	-21.57
CAediting_958304	chr13_36846049_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6791-5p	36846049	36846055	7mer-m8	36846048	36846068	144.00	-26.34
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6724-5p	36846052	36846058	7mer-m8	36846051	36846072	145.00	-25.05
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6724-5p	36846052	36846058	7mer-m8	36846051	36846072	145.00	-25.05
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6724-5p	36846052	36846058	7mer-m8	36846051	36846072	145.00	-25.05
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6724-5p	36846052	36846058	7mer-m8	36846051	36846072	145.00	-25.05
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6773-5p	36846052	36846058	7mer-m8	36846051	36846073	153.00	-23.29
CAediting_958307	chr13_36846075_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3176	36846075	36846081	7mer-m8	36846074	36846092	140.00	-15.24
CAediting_958307	chr13_36846075_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3922-3p	36846075	36846081	7mer-m8	36846074	36846095	141.00	-19.73
CAediting_958315	chr13_36846226_-	ENSG00000120693.12	ENST00000379826	hsa-miR-106a-3p	36846224	36846229	6mer	36846223	36846244	141.00	-21.13
CAediting_958317	chr13_36846239_-	ENSG00000120693.12	ENST00000379826	hsa-miR-326	36846237	36846243	7mer-m8	36846236	36846255	140.00	-13.25
CAediting_958317	chr13_36846239_-	ENSG00000120693.12	ENST00000379826	hsa-miR-330-5p	36846237	36846243	7mer-m8	36846236	36846259	143.00	-20.01
CAediting_958317	chr13_36846239_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4314	36846238	36846244	7mer-m8	36846237	36846255	143.00	-20.84
CAediting_958317	chr13_36846239_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846236	36846242	7mer-m8	36846235	36846258	150.00	-18.62
CAediting_958317	chr13_36846239_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846236	36846242	7mer-m8	36846235	36846258	150.00	-18.62
CAediting_958317	chr13_36846239_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846236	36846242	7mer-m8	36846235	36846258	150.00	-18.62
CAediting_958318	chr13_36846240_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6771-5p	36846238	36846245	8mer-1a	36846238	36846257	152.00	-26.14
CAediting_958320	chr13_36846261_-	ENSG00000120693.12	ENST00000379826	hsa-miR-140-3p	36846260	36846265	6mer	36846259	36846279	142.00	-17.02
CAediting_958321	chr13_36846277_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4524a-3p	36846273	36846279	7mer-m8	36846272	36846295	158.00	-19.98
CAediting_958321	chr13_36846277_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4524b-3p	36846274	36846279	6mer	36846273	36846293	140.00	-21.40
CAediting_958322	chr13_36846293_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3190-5p	36846287	36846294	8mer-1a	36846287	36846305	144.00	-16.77
CAediting_958322	chr13_36846293_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4701-5p	36846289	36846295	7mer-m8	36846288	36846309	150.00	-27.81
CAediting_958322	chr13_36846293_-	ENSG00000120693.12	ENST00000379826	hsa-miR-588	36846289	36846295	7mer-m8	36846288	36846307	161.00	-22.50
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6771-5p	36846366	36846372	7mer-m8	36846365	36846384	160.00	-34.33
CAediting_958330	chr13_36846428_-	ENSG00000120693.12	ENST00000379826	hsa-miR-548ao-3p	36846424	36846429	6mer	36846423	36846447	142.00	-19.91
CAediting_958332	chr13_36846444_-	ENSG00000120693.12	ENST00000379826	hsa-miR-1234-3p	36846444	36846450	7mer-m8	36846443	36846464	150.00	-18.25
CAediting_958332	chr13_36846444_-	ENSG00000120693.12	ENST00000379826	hsa-miR-7107-5p	36846444	36846450	7mer-m8	36846443	36846465	155.00	-27.12
CAediting_958333	chr13_36846449_-	ENSG00000120693.12	ENST00000379826	hsa-miR-1538	36846444	36846451	8mer-1a	36846444	36846467	147.00	-21.44
CAediting_958333	chr13_36846449_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4745-3p	36846444	36846451	8mer-1a	36846444	36846466	154.00	-28.59
CAediting_958333	chr13_36846449_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4783-3p	36846447	36846453	7mer-m8	36846446	36846468	161.00	-24.78

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_958305	chr13_36846052_-	ENSG00000120693.12	ENST00000379826	hsa-miR-10400-3p	36846052	36846058	7mer-m8	36846051	36846070	145	-20.89
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-10400-3p	36846052	36846058	7mer-m8	36846051	36846070	145	-20.89
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-12126	36846363	36846370	8mer-1a	36846363	36846386	147	-13.23
CAediting_958304	chr13_36846049_-	ENSG00000120693.12	ENST00000379826	hsa-miR-1343-3p	36846049	36846055	7mer-m8	36846048	36846071	143	-24.03
CAediting_958305	chr13_36846052_-	ENSG00000120693.12	ENST00000379826	hsa-miR-1343-3p	36846049	36846055	7mer-m8	36846048	36846071	143	-24.03
CAediting_958309	chr13_36846081_-	ENSG00000120693.12	ENST00000379826	hsa-miR-150-5p	36846080	36846086	7mer-m8	36846079	36846102	142	-15.8
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-24-3p	36846054	36846060	7mer-m8	36846053	36846074	146	-16.13
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-24-3p	36846054	36846060	7mer-m8	36846053	36846074	146	-16.13
CAediting_958322	chr13_36846293_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3064-5p	36846287	36846293	7mer-1a	36846287	36846307	152	-27.61
CAediting_958322	chr13_36846293_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3085-3p	36846287	36846293	7mer-1a	36846287	36846307	150	-26.89
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-30b-3p	36846366	36846373	8mer-1a	36846366	36846387	151	-15.38
CAediting_958318	chr13_36846240_-	ENSG00000120693.12	ENST00000379826	hsa-miR-30b-3p	36846239	36846246	8mer-1a	36846239	36846260	151	-16.71
CAediting_958299	chr13_36846020_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3149	36846017	36846023	7mer-m8	36846016	36846037	151	-11.65
CAediting_958329	chr13_36846418_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3174	36846416	36846421	6mer	36846415	36846435	142	-22.5
CAediting_958313	chr13_36846114_-	ENSG00000120693.12	ENST00000379826	hsa-miR-324-3p	36846110	36846116	7mer-m8	36846109	36846132	154	-20.9
CAediting_958293	chr13_36845246_-	ENSG00000120693.12	ENST00000379826	hsa-miR-362-5p	36845241	36845247	7mer-1a	36845241	36845264	140	-13.56
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3689a-3p	36846366	36846373	8mer-1a	36846366	36846386	147	-18.72
CAediting_958318	chr13_36846240_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3689a-3p	36846239	36846246	8mer-1a	36846239	36846259	147	-22.03
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3689b-3p	36846366	36846373	8mer-1a	36846366	36846386	147	-17.55
CAediting_958318	chr13_36846240_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3689b-3p	36846239	36846246	8mer-1a	36846239	36846259	147	-20.79
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3689c	36846366	36846373	8mer-1a	36846366	36846386	147	-17.55
CAediting_958318	chr13_36846240_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3689c	36846239	36846246	8mer-1a	36846239	36846259	147	-20.79
CAediting_958328	chr13_36846412_-	ENSG00000120693.12	ENST00000379826	hsa-miR-377-5p	36846408	36846414	7mer-m8	36846407	36846428	155	-19.35
CAediting_958332	chr13_36846444_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3922-3p	36846442	36846449	8mer-1a	36846442	36846465	148	-19.78
CAediting_958321	chr13_36846277_-	ENSG00000120693.12	ENST00000379826	hsa-miR-3976	36846276	36846282	7mer-m8	36846275	36846298	148	-13.06
CAediting_958313	chr13_36846114_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4252	36846109	36846115	7mer-m8	36846108	36846127	149	-20.66
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4330	36846056	36846062	7mer-m8	36846055	36846071	150	-14.11
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4437	36846052	36846059	8mer-1a	36846052	36846072	146	-20.1
CAediting_958327	chr13_36846375_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4478	36846371	36846377	7mer-m8	36846370	36846385	149	-25.05
CAediting_958319	chr13_36846248_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4478	36846244	36846250	7mer-m8	36846243	36846259	150	-23.72
CAediting_958327	chr13_36846375_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4649-3p	36846374	36846380	7mer-m8	36846373	36846393	140	-14.3
CAediting_958319	chr13_36846248_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4649-3p	36846247	36846253	7mer-m8	36846246	36846266	147	-14.72
CAediting_958305	chr13_36846052_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4674	36846052	36846058	7mer-m8	36846051	36846071	147	-22.84
CAediting_958306	chr13_36846057_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4674	36846052	36846058	7mer-m8	36846051	36846071	147	-22.84
CAediting_958324	chr13_36846315_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4684-5p	36846311	36846317	7mer-m8	36846310	36846331	151	-12.03
CAediting_958322	chr13_36846293_-	ENSG00000120693.12	ENST00000379826	hsa-miR-4794	36846287	36846294	8mer-1a	36846287	36846309	155	-23.02
CAediting_958319	chr13_36846248_-	ENSG00000120693.12	ENST00000379826	hsa-miR-485-5p	36846243	36846249	7mer-m8	36846242	36846264	149	-17.54
CAediting_958320	chr13_36846261_-	ENSG00000120693.12	ENST00000379826	hsa-miR-513b-5p	36846261	36846267	7mer-m8	36846260	36846281	146	-14.09
CAediting_958331	chr13_36846442_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846440	36846446	7mer-m8	36846439	36846462	152	-23.9
CAediting_958332	chr13_36846444_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846440	36846446	7mer-m8	36846439	36846462	152	-23.9
CAediting_958331	chr13_36846442_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846440	36846446	7mer-m8	36846439	36846462	152	-23.9
CAediting_958332	chr13_36846444_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846440	36846446	7mer-m8	36846439	36846462	152	-23.9
CAediting_958331	chr13_36846442_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846440	36846446	7mer-m8	36846439	36846462	152	-23.9
CAediting_958332	chr13_36846444_-	ENSG00000120693.12	ENST00000379826	hsa-miR-514a-5p	36846440	36846446	7mer-m8	36846439	36846462	152	-23.9
CAediting_958330	chr13_36846428_-	ENSG00000120693.12	ENST00000379826	hsa-miR-5694	36846425	36846430	6mer	36846424	36846445	150	-22.24
CAediting_958324	chr13_36846315_-	ENSG00000120693.12	ENST00000379826	hsa-miR-593-3p	36846310	36846315	6mer	36846309	36846327	140	-18.96
CAediting_958328	chr13_36846412_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6086	36846408	36846414	7mer-m8	36846407	36846426	148	-19
CAediting_958310	chr13_36846098_-	ENSG00000120693.12	ENST00000379826	hsa-miR-625-3p	36846096	36846102	7mer-m8	36846095	36846116	152	-12.62
CAediting_958311	chr13_36846100_-	ENSG00000120693.12	ENST00000379826	hsa-miR-625-3p	36846096	36846102	7mer-m8	36846095	36846116	152	-12.62
CAediting_958328	chr13_36846412_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6516-5p	36846412	36846418	7mer-m8	36846411	36846434	145	-14.71
CAediting_958322	chr13_36846293_-	ENSG00000120693.12	ENST00000379826	hsa-miR-664a-5p	36846287	36846294	8mer-1a	36846287	36846310	140	-15.89
CAediting_958319	chr13_36846248_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6765-5p	36846248	36846254	7mer-m8	36846247	36846274	154	-27.66
CAediting_958309	chr13_36846081_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6778-3p	36846078	36846084	7mer-m8	36846077	36846097	143	-13.97
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6779-5p	36846366	36846373	8mer-1a	36846366	36846384	148	-22.58
CAediting_958318	chr13_36846240_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6779-5p	36846239	36846246	8mer-1a	36846239	36846257	148	-23.32
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6780a-5p	36846366	36846373	8mer-1a	36846366	36846389	152	-25.37
CAediting_958318	chr13_36846240_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6780a-5p	36846239	36846246	8mer-1a	36846239	36846262	152	-21.42
CAediting_958304	chr13_36846049_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6783-3p	36846049	36846055	7mer-m8	36846048	36846069	151	-25.03
CAediting_958305	chr13_36846052_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6783-3p	36846049	36846055	7mer-m8	36846048	36846069	151	-25.03
CAediting_958313	chr13_36846114_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6807-3p	36846112	36846118	7mer-m8	36846111	36846132	150	-18.87
CAediting_958329	chr13_36846418_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6807-5p	36846418	36846424	7mer-m8	36846417	36846438	144	-19.38
CAediting_958312	chr13_36846106_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6807-5p	36846106	36846112	7mer-m8	36846105	36846125	154	-19.16
CAediting_958331	chr13_36846442_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6824-3p	36846441	36846446	6mer	36846440	36846462	143	-20.18
CAediting_958332	chr13_36846444_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6824-3p	36846441	36846446	6mer	36846440	36846462	143	-20.18
CAediting_958308	chr13_36846076_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6878-3p	36846075	36846082	8mer-1a	36846075	36846095	142	-14.14
CAediting_958309	chr13_36846081_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6878-3p	36846075	36846082	8mer-1a	36846075	36846095	142	-14.14
CAediting_958319	chr13_36846248_-	ENSG00000120693.12	ENST00000379826	hsa-miR-6884-5p	36846243	36846249	7mer-m8	36846242	36846263	154	-23.23
CAediting_958327	chr13_36846375_-	ENSG00000120693.12	ENST00000379826	hsa-miR-7160-5p	36846373	36846379	7mer-m8	36846372	36846392	146	-17.63
CAediting_958319	chr13_36846248_-	ENSG00000120693.12	ENST00000379826	hsa-miR-7160-5p	36846246	36846252	7mer-m8	36846245	36846263	154	-22.76
CAediting_958295	chr13_36845287_-	ENSG00000120693.12	ENST00000379826	hsa-miR-758-5p	36845282	36845288	7mer-m8	36845281	36845302	145	-12.88
CAediting_958323	chr13_36846301_-	ENSG00000120693.12	ENST00000379826	hsa-miR-7855-5p	36846298	36846303	6mer	36846297	36846317	140	-24.29
CAediting_958310	chr13_36846098_-	ENSG00000120693.12	ENST00000379826	hsa-miR-8052	36846092	36846098	7mer-1a	36846092	36846110	144	-25.51
CAediting_958326	chr13_36846367_-	ENSG00000120693.12	ENST00000379826	hsa-miR-887-5p	36846366	36846372	7mer-m8	36846365	36846384	143	-19.73
CAediting_958317	chr13_36846239_-	ENSG00000120693.12	ENST00000379826	hsa-miR-887-5p	36846238	36846245	8mer-1a	36846238	36846257	143	-13.53
CAediting_958318	chr13_36846240_-	ENSG00000120693.12	ENST00000379826	hsa-miR-887-5p	36846238	36846245	8mer-1a	36846238	36846257	143	-13.53
CAediting_958305	chr13_36846052_-	ENSG00000120693.12	ENST00000379826	hsa-miR-939-3p	36846049	36846056	8mer-1a	36846049	36846071	148	-23.16
CAediting_958294	chr13_36845257_-	ENSG00000120693.12	ENST00000379826	hsa-miR-95-5p	36845254	36845260	7mer-m8	36845253	36845273	140	-5.14

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000120693.12	ENST00000379826	hsa-miR-624-3p	36845981	36845987	7mer-m8	36845980	36846000	148	-11.86
CAediting_1160181	chr17_7017644_-	ENSG00000120693.12	ENST00000379826	hsa-miR-195-3p	36845470	36845477	8mer-1a	36845470	36845493	145	-12.18
CAediting_1160181	chr17_7017644_-	ENSG00000120693.12	ENST00000379826	hsa-miR-195-3p	36848320	36848327	8mer-1a	36848320	36848340	158	-18.74
CAediting_1351755	chr19_40282625_-	ENSG00000120693.12	ENST00000379826	hsa-miR-641	36846695	36846702	8mer-1a	36846695	36846718	158	-17.44
CAediting_1351755	chr19_40282625_-	ENSG00000120693.12	ENST00000379826	hsa-miR-641	36845838	36845845	8mer-1a	36845838	36845860	143	-11.75
CAediting_580943	chr7_100356700_+	ENSG00000120693.12	ENST00000379826	hsa-miR-6840-3p	36846397	36846403	7mer-m8	36846396	36846417	140	-25.13

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000120693.12	ENST00000379826	hsa-miR-200b-3p	36845695	36845701	7mer-m8	36845694	36845715	147	-9.39
CAediting_1306324	chr19_13836464_-	ENSG00000120693.12	ENST00000379826	hsa-miR-27a-3p	36848073	36848079	7mer-m8	36848072	36848094	144	-10.15
CAediting_1306324	chr19_13836464_-	ENSG00000120693.12	ENST00000379826	hsa-miR-27a-3p	36848049	36848056	8mer-1a	36848049	36848069	140	-12.57
CAediting_228905	chr2_188297554_+	ENSG00000120693.12	ENST00000379826	hsa-miR-561-3p	36847093	36847099	7mer-m8	36847092	36847113	143	-4.43
CAediting_228905	chr2_188297554_+	ENSG00000120693.12	ENST00000379826	hsa-miR-561-3p	36848145	36848152	8mer-1a	36848145	36848166	140	-6.99
CAediting_228905	chr2_188297554_+	ENSG00000120693.12	ENST00000379826	hsa-miR-561-3p	36847834	36847840	7mer-m8	36847833	36847857	153	-13.67
CAediting_980496	chr14_31014685_-	ENSG00000120693.12	ENST00000379826	hsa-miR-624-3p	36846263	36846269	7mer-m8	36846262	36846282	144	-15.07
CAediting_580943	chr7_100356700_+	ENSG00000120693.12	ENST00000379826	hsa-miR-6840-3p	36847703	36847710	8mer-1a	36847703	36847725	151	-27.77

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SMAD9

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for SMAD9

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_958298	chr13_36846007_-	1.90509058675139e-11	0.533554461280536	.	.	.	.
LGG	CAediting_958305	chr13_36846052_-	6.92689500494978e-06	0.338109154463502	.	.	.	.
LGG	CAediting_958310	chr13_36846098_-	5.2227651415457e-09	0.266342320528722	.	.	.	.
BRCA	CAediting_958310	chr13_36846098_-	.	.	.	.	0.000120833491427455	0.409526775862945
LUAD	CAediting_958310	chr13_36846098_-	0.000590614918285299	0.434196338361103	.	.	.	.
GBM	CAediting_958310	chr13_36846098_-	8.3511647982762e-05	0.344502912480689	.	.	.	.
PRAD	CAediting_958310	chr13_36846098_-	7.0284732869567e-05	0.262984067866141	.	.	.	.
STAD	CAediting_958310	chr13_36846098_-	0.0361778710448671	0.23033910966529	.	.	.	.
THCA	CAediting_958310	chr13_36846098_-	1.57456593969781e-09	0.325437609073415	.	.	.	.
KIRC	CAediting_958310	chr13_36846098_-	0.00387005248132421	0.153592742918308	.	.	.	.
PCPG	CAediting_958310	chr13_36846098_-	0.000230108525088033	0.432513275315178	.	.	.	.
TGCT	CAediting_958310	chr13_36846098_-	2.52909908323242e-06	0.569354480138129	.	.	.	.
LGG	CAediting_958311	chr13_36846100_-	3.76295113942488e-05	0.181964243199056	.	.	.	.
BRCA	CAediting_958311	chr13_36846100_-	0.00117982413609643	0.259020540446112	.	.	.	.
LUAD	CAediting_958311	chr13_36846100_-	6.30991448507565e-05	0.378528216906461	.	.	.	.
COAD	CAediting_958311	chr13_36846100_-	0.000424475831079775	0.337818810650111	.	.	.	.
LUSC	CAediting_958311	chr13_36846100_-	0.00356522546359752	0.35380100616634	.	.	.	.
GBM	CAediting_958311	chr13_36846100_-	2.30327670256429e-05	0.335041752495521	.	.	.	.
PRAD	CAediting_958311	chr13_36846100_-	2.57580075428342e-15	0.367388266381794	.	.	.	.
STAD	CAediting_958311	chr13_36846100_-	0.0278944516740415	0.205091871609968	0.0144525897490545	0.227558526698958	.	.
THCA	CAediting_958311	chr13_36846100_-	1.33821615378658e-25	0.461585934403467	.	.	.	.
KIRC	CAediting_958311	chr13_36846100_-	3.85784798132776e-09	0.277640069643564	.	.	.	.
UCEC	CAediting_958311	chr13_36846100_-	4.19419374465693e-06	0.441800407850046	.	.	.	.
OV	CAediting_958311	chr13_36846100_-	0.00598704265493126	0.376180946634015	.	.	.	.
PCPG	CAediting_958311	chr13_36846100_-	1.0988516342034e-07	0.488273914459291	.	.	.	.
SARC	CAediting_958311	chr13_36846100_-	0.00161652805193849	0.353416725515382	.	.	.	.
TGCT	CAediting_958311	chr13_36846100_-	1.66518113837248e-06	0.540156806066519	.	.	.	.
LGG	CAediting_958313	chr13_36846114_-	0.00155324835639997	0.228646657950244	.	.	.	.
LGG	CAediting_958314	chr13_36846224_-	3.6555773671716e-12	0.367190482264474	.	.	.	.
GBM	CAediting_958314	chr13_36846224_-	0.00397117594509423	0.337734433129181	.	.	.	.
THCA	CAediting_958314	chr13_36846224_-	0.00255078172813628	0.312646511014362	.	.	.	.
KIRC	CAediting_958314	chr13_36846224_-	0.00321350731960257	0.219695613612847	.	.	.	.
LGG	CAediting_958316	chr13_36846238_-	3.46707474759142e-09	0.29567794781471	.	.	.	.
GBM	CAediting_958316	chr13_36846238_-	0.000174436795737711	0.319887948525823	.	.	.	.
PRAD	CAediting_958316	chr13_36846238_-	0.00390984709477007	0.218926601600684	.	.	.	.
THCA	CAediting_958316	chr13_36846238_-	3.62955684545798e-08	0.356268604766326	.	.	.	.
KIRC	CAediting_958316	chr13_36846238_-	0.00116670695738659	0.214180218419818	.	.	.	.
LGG	CAediting_958317	chr13_36846239_-	5.30614233774778e-05	0.353320933644745	.	.	.	.
GBM	CAediting_958317	chr13_36846239_-	0.00918953398591753	0.354560997277724	.	.	.	.
LGG	CAediting_958319	chr13_36846248_-	6.22953080405446e-13	0.391890635559319	.	.	.	.
GBM	CAediting_958319	chr13_36846248_-	2.22813538375952e-05	0.402935738340309	.	.	.	.
STAD	CAediting_958319	chr13_36846248_-	0.0015260220638187	0.397216453589842	.	.	.	.
THCA	CAediting_958319	chr13_36846248_-	0.0091864171812544	0.26058572991967	.	.	.	.
KIRC	CAediting_958319	chr13_36846248_-	0.00257739376401382	0.248519493917524	.	.	.	.
LGG	CAediting_958327	chr13_36846375_-	1.96223901497264e-06	0.506016316110585	.	.	.	.

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Relation with cancer stages for SMAD9

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRP	pathologic_stage	CAediting_958310	chr13_36846098_-	0.0278156737965796	0.217881498614744
THCA	pathologic_stage	CAediting_958311	chr13_36846100_-	0.0011533982288289	0.152235494801413
THCA	pathologic_stage	CAediting_958316	chr13_36846238_-	0.00224005283385	0.20321673651497

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Relation with survival for SMAD9

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for SMAD9

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SMAD9

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
SMAD9	C0340543	Familial primary pulmonary hypertension	2	CTD_human;GENOMICS_ENGLAND;ORPHANET
SMAD9	C3888002	PULMONARY HYPERTENSION, PRIMARY, 2	2	GENOMICS_ENGLAND;UNIPROT
SMAD9	C0009402	Colorectal Carcinoma	1	CTD_human
SMAD9	C0009404	Colorectal Neoplasms	1	CTD_human
SMAD9	C0152171	Idiopathic pulmonary hypertension	1	GENOMICS_ENGLAND
SMAD9	C1150929	2-oxo-hept-3-ene-1,7-dioate hydratase activity	1	GENOMICS_ENGLAND
SMAD9	C1701939	Familial pulmonary arterial hypertension	1	ORPHANET
SMAD9	C2973725	Pulmonary arterial hypertension	1	GENOMICS_ENGLAND
SMAD9	C3203102	Idiopathic pulmonary arterial hypertension	1	CTD_human;GENOMICS_ENGLAND
SMAD9	C3272802	Hamartomatous polyposis	1	GENOMICS_ENGLAND

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene