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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: LTBP3 (CAeditome ID:4054)

Gene summary for LTBP3

check button Gene summary
Gene informationGene symbol

LTBP3

Gene ID

4054

Gene namelatent transforming growth factor beta binding protein 3
SynonymsDASS|GPHYSD3|LTBP-3|LTBP2|STHAG6|pp6425
Cytomap

11q13.1

Type of geneprotein-coding
Descriptionlatent-transforming growth factor beta-binding protein 3latent TGF beta binding protein 3
Modification date20210518
UniProtAcc

Q9NS15

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
LTBP3

GO:0062023

Latent-transforming growth factor beta-binding protein 3

16157329


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RNA A-to-I events for LTBP3

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000168056.13
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_824698(65542460, -), CAediting_824699(65542476, -), CAediting_824700(65542497, -), CAediting_824701(65542534, -), CAediting_824702(65542541, -), CAediting_824703(65542606, -), CAediting_824704(65544929, -), CAediting_824705(65545041, -), CAediting_824706(65545378, -), CAediting_824707(65546287, -), CAediting_824708(65549420, -), CAediting_824709(65549435, -), CAediting_824710(65549446, -), CAediting_824711(65549448, -), CAediting_824712(65549464, -), CAediting_824713(65549469, -), CAediting_824714(65549477, -), CAediting_824715(65549479, -), CAediting_824716(65549480, -), CAediting_824717(65549484, -), CAediting_824718(65549488, -), CAediting_824719(65549495, -), CAediting_824720(65549497, -), CAediting_824721(65549499, -), CAediting_824722(65549501, -), CAediting_824723(65549508, -), CAediting_824724(65549509, -), CAediting_824725(65549514, -), CAediting_824726(65549518, -), CAediting_824727(65549537, -), CAediting_824728(65549545, -), CAediting_824729(65549563, -), CAediting_824730(65549569, -), CAediting_824731(65549570, -), CAediting_824732(65549571, -), CAediting_824733(65549573, -), CAediting_824734(65549619, -), CAediting_824735(65549621, -), CAediting_824736(65549623, -), CAediting_824737(65549624, -), CAediting_824738(65549636, -), CAediting_824739(65549638, -), CAediting_824740(65549644, -), CAediting_824741(65549646, -), CAediting_824742(65549647, -), CAediting_824743(65549652, -), CAediting_824744(65549655, -), CAediting_824745(65549682, -), CAediting_824746(65549685, -), CAediting_824747(65549690, -), CAediting_824748(65549691, -), CAediting_824749(65549699, -), CAediting_824750(65549707, -), CAediting_824751(65549714, -), CAediting_824752(65549731, -), CAediting_824753(65549799, -), CAediting_824754(65549805, -), CAediting_824755(65549811, -), CAediting_824756(65549812, -), CAediting_824757(65549813, -), CAediting_824758(65549852, -), CAediting_824759(65549859, -), CAediting_824760(65549861, -), CAediting_824761(65549864, -), CAediting_824762(65549871, -), CAediting_824763(65549874, -), CAediting_824764(65549883, -), CAediting_824765(65549894, -), CAediting_824766(65549906, -), CAediting_824767(65549914, -), CAediting_824768(65549918, -), CAediting_824769(65550137, -), CAediting_824770(65550144, -), CAediting_824771(65550153, -), CAediting_824772(65550165, -), CAediting_824773(65550166, -), CAediting_824774(65550167, -), CAediting_824775(65550188, -), CAediting_824776(65550196, -), CAediting_824777(65550213, -), CAediting_824778(65550216, -), CAediting_824779(65550219, -), CAediting_824780(65550220, -), CAediting_824781(65550225, -), CAediting_824782(65550228, -), CAediting_824783(65550242, -), CAediting_824784(65550245, -), CAediting_824785(65550251, -), CAediting_824786(65550264, -), CAediting_824787(65550274, -), CAediting_824788(65550277, -), CAediting_824789(65550280, -), CAediting_824790(65550288, -), CAediting_824791(65550290, -), CAediting_824792(65550300, -), CAediting_824793(65550349, -), CAediting_824794(65550355, -), CAediting_824795(65550365, -), CAediting_824796(65550386, -), CAediting_824797(65550410, -), CAediting_824798(65550559, -), CAediting_824799(65550560, -), CAediting_824800(65550563, -), CAediting_824801(65550567, -), CAediting_824802(65550569, -), CAediting_824803(65550581, -), CAediting_824804(65550582, -), CAediting_824805(65550583, -), CAediting_824806(65550604, -), CAediting_824807(65550612, -), CAediting_824808(65550632, -), CAediting_824809(65550641, -), CAediting_824810(65550644, -), CAediting_824811(65550658, -), CAediting_824812(65550661, -), CAediting_824813(65550680, -), CAediting_824814(65550696, -), CAediting_824815(65550700, -), CAediting_824816(65550702, -), CAediting_824817(65550712, -), CAediting_824818(65550741, -), CAediting_824819(65550762, -), CAediting_824820(65550767, -), CAediting_824821(65550777, -), CAediting_824822(65550786, -), CAediting_824823(65550798, -), CAediting_824824(65550819, -), CAediting_824825(65550821, -),

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RNA editing positional annotations for LTBP3 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_824698chr11_65542460_-ncRNA_exonic
CAediting_824699chr11_65542476_-ncRNA_exonic
CAediting_824700chr11_65542497_-ncRNA_exonic
CAediting_824701chr11_65542534_-ncRNA_exonic
CAediting_824702chr11_65542541_-ncRNA_exonic
CAediting_824703chr11_65542606_-ncRNA_exonic
CAediting_824704chr11_65544929_-ncRNA_exonic
CAediting_824705chr11_65545041_-ncRNA_exonic
CAediting_824706chr11_65545378_-ncRNA_exonic
CAediting_824707chr11_65546287_-UTR3
CAediting_824708chr11_65549420_-ncRNA_intronic
CAediting_824709chr11_65549435_-ncRNA_intronic
CAediting_824710chr11_65549446_-ncRNA_intronic
CAediting_824711chr11_65549448_-ncRNA_intronic
CAediting_824712chr11_65549464_-ncRNA_intronic
CAediting_824713chr11_65549469_-ncRNA_intronic
CAediting_824714chr11_65549477_-ncRNA_intronic
CAediting_824715chr11_65549479_-ncRNA_intronic
CAediting_824716chr11_65549480_-ncRNA_intronic
CAediting_824717chr11_65549484_-ncRNA_intronic
CAediting_824718chr11_65549488_-ncRNA_intronic
CAediting_824719chr11_65549495_-ncRNA_intronic
CAediting_824720chr11_65549497_-ncRNA_intronic
CAediting_824721chr11_65549499_-ncRNA_intronic
CAediting_824722chr11_65549501_-ncRNA_intronic
CAediting_824723chr11_65549508_-ncRNA_intronic
CAediting_824724chr11_65549509_-ncRNA_intronic
CAediting_824725chr11_65549514_-ncRNA_intronic
CAediting_824726chr11_65549518_-ncRNA_intronic
CAediting_824727chr11_65549537_-ncRNA_intronic
CAediting_824728chr11_65549545_-ncRNA_intronic
CAediting_824729chr11_65549563_-ncRNA_intronic
CAediting_824730chr11_65549569_-ncRNA_intronic
CAediting_824731chr11_65549570_-ncRNA_intronic
CAediting_824732chr11_65549571_-ncRNA_intronic
CAediting_824733chr11_65549573_-ncRNA_intronic
CAediting_824734chr11_65549619_-ncRNA_intronic
CAediting_824735chr11_65549621_-ncRNA_intronic
CAediting_824736chr11_65549623_-ncRNA_intronic
CAediting_824737chr11_65549624_-ncRNA_intronic
CAediting_824738chr11_65549636_-ncRNA_intronic
CAediting_824739chr11_65549638_-ncRNA_intronic
CAediting_824740chr11_65549644_-ncRNA_intronic
CAediting_824741chr11_65549646_-ncRNA_intronic
CAediting_824742chr11_65549647_-ncRNA_intronic
CAediting_824743chr11_65549652_-ncRNA_intronic
CAediting_824744chr11_65549655_-ncRNA_intronic
CAediting_824745chr11_65549682_-ncRNA_intronic
CAediting_824746chr11_65549685_-ncRNA_intronic
CAediting_824747chr11_65549690_-ncRNA_intronic
CAediting_824748chr11_65549691_-ncRNA_intronic
CAediting_824749chr11_65549699_-ncRNA_intronic
CAediting_824750chr11_65549707_-ncRNA_intronic
CAediting_824751chr11_65549714_-ncRNA_intronic
CAediting_824752chr11_65549731_-ncRNA_intronic
CAediting_824753chr11_65549799_-ncRNA_intronic
CAediting_824754chr11_65549805_-ncRNA_intronic
CAediting_824755chr11_65549811_-ncRNA_intronic
CAediting_824756chr11_65549812_-ncRNA_intronic
CAediting_824757chr11_65549813_-ncRNA_intronic
CAediting_824758chr11_65549852_-ncRNA_intronic
CAediting_824759chr11_65549859_-ncRNA_intronic
CAediting_824760chr11_65549861_-ncRNA_intronic
CAediting_824761chr11_65549864_-ncRNA_intronic
CAediting_824762chr11_65549871_-ncRNA_intronic
CAediting_824763chr11_65549874_-ncRNA_intronic
CAediting_824764chr11_65549883_-ncRNA_intronic
CAediting_824765chr11_65549894_-ncRNA_intronic
CAediting_824766chr11_65549906_-ncRNA_intronic
CAediting_824767chr11_65549914_-ncRNA_intronic
CAediting_824768chr11_65549918_-ncRNA_intronic
CAediting_824769chr11_65550137_-ncRNA_intronic
CAediting_824770chr11_65550144_-ncRNA_intronic
CAediting_824771chr11_65550153_-ncRNA_intronic
CAediting_824772chr11_65550165_-ncRNA_intronic
CAediting_824773chr11_65550166_-ncRNA_intronic
CAediting_824774chr11_65550167_-ncRNA_intronic
CAediting_824775chr11_65550188_-ncRNA_intronic
CAediting_824776chr11_65550196_-ncRNA_intronic
CAediting_824777chr11_65550213_-ncRNA_intronic
CAediting_824778chr11_65550216_-ncRNA_intronic
CAediting_824779chr11_65550219_-ncRNA_intronic
CAediting_824780chr11_65550220_-ncRNA_intronic
CAediting_824781chr11_65550225_-ncRNA_intronic
CAediting_824782chr11_65550228_-ncRNA_intronic
CAediting_824783chr11_65550242_-ncRNA_intronic
CAediting_824784chr11_65550245_-ncRNA_intronic
CAediting_824785chr11_65550251_-ncRNA_intronic
CAediting_824786chr11_65550264_-ncRNA_intronic
CAediting_824787chr11_65550274_-ncRNA_intronic
CAediting_824788chr11_65550277_-ncRNA_intronic
CAediting_824789chr11_65550280_-ncRNA_intronic
CAediting_824790chr11_65550288_-ncRNA_intronic
CAediting_824791chr11_65550290_-ncRNA_intronic
CAediting_824792chr11_65550300_-ncRNA_intronic
CAediting_824793chr11_65550349_-ncRNA_intronic
CAediting_824794chr11_65550355_-ncRNA_intronic
CAediting_824795chr11_65550365_-ncRNA_intronic
CAediting_824796chr11_65550386_-ncRNA_intronic
CAediting_824797chr11_65550410_-ncRNA_intronic
CAediting_824798chr11_65550559_-ncRNA_intronic
CAediting_824799chr11_65550560_-ncRNA_intronic
CAediting_824800chr11_65550563_-ncRNA_intronic
CAediting_824801chr11_65550567_-ncRNA_intronic
CAediting_824802chr11_65550569_-ncRNA_intronic
CAediting_824803chr11_65550581_-ncRNA_intronic
CAediting_824804chr11_65550582_-ncRNA_intronic
CAediting_824805chr11_65550583_-ncRNA_intronic
CAediting_824806chr11_65550604_-ncRNA_intronic
CAediting_824807chr11_65550612_-ncRNA_intronic
CAediting_824808chr11_65550632_-ncRNA_intronic
CAediting_824809chr11_65550641_-ncRNA_intronic
CAediting_824810chr11_65550644_-ncRNA_intronic
CAediting_824811chr11_65550658_-ncRNA_intronic
CAediting_824812chr11_65550661_-ncRNA_intronic
CAediting_824813chr11_65550680_-ncRNA_intronic
CAediting_824814chr11_65550696_-ncRNA_intronic
CAediting_824815chr11_65550700_-ncRNA_intronic
CAediting_824816chr11_65550702_-ncRNA_intronic
CAediting_824817chr11_65550712_-ncRNA_intronic
CAediting_824818chr11_65550741_-ncRNA_intronic
CAediting_824819chr11_65550762_-ncRNA_intronic
CAediting_824820chr11_65550767_-ncRNA_intronic
CAediting_824821chr11_65550777_-ncRNA_intronic
CAediting_824822chr11_65550786_-ncRNA_intronic
CAediting_824823chr11_65550798_-ncRNA_intronic
CAediting_824824chr11_65550819_-ncRNA_intronic
CAediting_824825chr11_65550821_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_824698chr11_65542460_-SINEAluAluSx4
CAediting_824699chr11_65542476_-SINEAluAluSx4
CAediting_824700chr11_65542497_-SINEAluAluSx4
CAediting_824701chr11_65542534_-SINEAluAluSx4
CAediting_824702chr11_65542541_-SINEAluAluSx4
CAediting_824703chr11_65542606_-SINEAluAluSx4
CAediting_824706chr11_65545378_-LINEL2L2c
CAediting_824708chr11_65549420_-SINEAluAluSc
CAediting_824709chr11_65549435_-SINEAluAluSc
CAediting_824710chr11_65549446_-SINEAluAluSc
CAediting_824711chr11_65549448_-SINEAluAluSc
CAediting_824712chr11_65549464_-SINEAluAluSc
CAediting_824713chr11_65549469_-SINEAluAluSc
CAediting_824714chr11_65549477_-SINEAluAluSc
CAediting_824715chr11_65549479_-SINEAluAluSc
CAediting_824716chr11_65549480_-SINEAluAluSc
CAediting_824717chr11_65549484_-SINEAluAluSc
CAediting_824718chr11_65549488_-SINEAluAluSc
CAediting_824719chr11_65549495_-SINEAluAluSc
CAediting_824720chr11_65549497_-SINEAluAluSc
CAediting_824721chr11_65549499_-SINEAluAluSc
CAediting_824722chr11_65549501_-SINEAluAluSc
CAediting_824723chr11_65549508_-SINEAluAluSc
CAediting_824724chr11_65549509_-SINEAluAluSc
CAediting_824725chr11_65549514_-SINEAluAluSc
CAediting_824726chr11_65549518_-SINEAluAluSc
CAediting_824727chr11_65549537_-SINEAluAluSc
CAediting_824728chr11_65549545_-SINEAluAluSc
CAediting_824729chr11_65549563_-SINEAluAluSc
CAediting_824730chr11_65549569_-SINEAluAluSc
CAediting_824731chr11_65549570_-SINEAluAluSc
CAediting_824732chr11_65549571_-SINEAluAluSc
CAediting_824733chr11_65549573_-SINEAluAluSc
CAediting_824734chr11_65549619_-SINEAluAluSc
CAediting_824735chr11_65549621_-SINEAluAluSc
CAediting_824736chr11_65549623_-SINEAluAluSc
CAediting_824737chr11_65549624_-SINEAluAluSc
CAediting_824738chr11_65549636_-SINEAluAluSc
CAediting_824739chr11_65549638_-SINEAluAluSc
CAediting_824740chr11_65549644_-SINEAluAluSc
CAediting_824741chr11_65549646_-SINEAluAluSc
CAediting_824742chr11_65549647_-SINEAluAluSc
CAediting_824743chr11_65549652_-SINEAluAluSc
CAediting_824744chr11_65549655_-SINEAluAluSc
CAediting_824745chr11_65549682_-SINEAluAluSc
CAediting_824746chr11_65549685_-SINEAluAluSc
CAediting_824747chr11_65549690_-SINEAluAluSc
CAediting_824748chr11_65549691_-SINEAluAluSc
CAediting_824749chr11_65549699_-SINEAluAluSc
CAediting_824750chr11_65549707_-SINEAluAluSc
CAediting_824751chr11_65549714_-SINEAluAluSc
CAediting_824753chr11_65549799_-SINEAluAluJb
CAediting_824754chr11_65549805_-SINEAluAluJb
CAediting_824755chr11_65549811_-SINEAluAluJb
CAediting_824756chr11_65549812_-SINEAluAluJb
CAediting_824757chr11_65549813_-SINEAluAluJb
CAediting_824758chr11_65549852_-SINEAluAluJb
CAediting_824759chr11_65549859_-SINEAluAluJb
CAediting_824760chr11_65549861_-SINEAluAluJb
CAediting_824761chr11_65549864_-SINEAluAluJb
CAediting_824762chr11_65549871_-SINEAluAluJb
CAediting_824763chr11_65549874_-SINEAluAluJb
CAediting_824764chr11_65549883_-SINEAluAluJb
CAediting_824765chr11_65549894_-SINEAluAluJb
CAediting_824766chr11_65549906_-SINEAluAluJb
CAediting_824767chr11_65549914_-SINEAluAluJb
CAediting_824768chr11_65549918_-SINEAluAluJb
CAediting_824769chr11_65550137_-SINEAluAluY
CAediting_824770chr11_65550144_-SINEAluAluY
CAediting_824771chr11_65550153_-SINEAluAluY
CAediting_824772chr11_65550165_-SINEAluAluY
CAediting_824773chr11_65550166_-SINEAluAluY
CAediting_824774chr11_65550167_-SINEAluAluY
CAediting_824775chr11_65550188_-SINEAluAluY
CAediting_824776chr11_65550196_-SINEAluAluY
CAediting_824777chr11_65550213_-SINEAluAluY
CAediting_824778chr11_65550216_-SINEAluAluY
CAediting_824779chr11_65550219_-SINEAluAluY
CAediting_824780chr11_65550220_-SINEAluAluY
CAediting_824781chr11_65550225_-SINEAluAluY
CAediting_824782chr11_65550228_-SINEAluAluY
CAediting_824783chr11_65550242_-SINEAluAluY
CAediting_824784chr11_65550245_-SINEAluAluY
CAediting_824785chr11_65550251_-SINEAluAluY
CAediting_824786chr11_65550264_-SINEAluAluY
CAediting_824787chr11_65550274_-SINEAluAluY
CAediting_824788chr11_65550277_-SINEAluAluY
CAediting_824789chr11_65550280_-SINEAluAluY
CAediting_824790chr11_65550288_-SINEAluAluY
CAediting_824791chr11_65550290_-SINEAluAluY
CAediting_824792chr11_65550300_-SINEAluAluY
CAediting_824793chr11_65550349_-SINEAluAluY
CAediting_824794chr11_65550355_-SINEAluAluY
CAediting_824795chr11_65550365_-SINEAluAluY
CAediting_824796chr11_65550386_-SINEAluAluY
CAediting_824797chr11_65550410_-SINEAluAluY
CAediting_824798chr11_65550559_-SINEAluAluSc
CAediting_824799chr11_65550560_-SINEAluAluSc
CAediting_824800chr11_65550563_-SINEAluAluSc
CAediting_824801chr11_65550567_-SINEAluAluSc
CAediting_824802chr11_65550569_-SINEAluAluSc
CAediting_824803chr11_65550581_-SINEAluAluSc
CAediting_824804chr11_65550582_-SINEAluAluSc
CAediting_824805chr11_65550583_-SINEAluAluSc
CAediting_824806chr11_65550604_-SINEAluAluSc
CAediting_824807chr11_65550612_-SINEAluAluSc
CAediting_824808chr11_65550632_-SINEAluAluSc
CAediting_824809chr11_65550641_-SINEAluAluSc
CAediting_824810chr11_65550644_-SINEAluAluSc
CAediting_824811chr11_65550658_-SINEAluAluSc
CAediting_824812chr11_65550661_-SINEAluAluSc
CAediting_824813chr11_65550680_-SINEAluAluSc
CAediting_824814chr11_65550696_-SINEAluAluSc
CAediting_824815chr11_65550700_-SINEAluAluSc
CAediting_824816chr11_65550702_-SINEAluAluSc
CAediting_824817chr11_65550712_-SINEAluAluSc
CAediting_824818chr11_65550741_-SINEAluAluSc
CAediting_824819chr11_65550762_-SINEAluAluSc
CAediting_824820chr11_65550767_-SINEAluAluSc
CAediting_824821chr11_65550777_-SINEAluAluSc
CAediting_824822chr11_65550786_-SINEAluAluSc
CAediting_824823chr11_65550798_-SINEAluAluSc
CAediting_824824chr11_65550819_-SINEAluAluSc
CAediting_824825chr11_65550821_-SINEAluAluSc

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RNA A-to-I editing events in the alternative splicing sites for LTBP3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000168056.13.LTBP3.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000168056.13.LTBP3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LTBP3

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
GBM.CAediting_824715.ENSG00000168056.LTBP3.png
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GBM.CAediting_824821.ENSG00000168056.LTBP3.png
Soverview
KIRC.CAediting_824755.ENSG00000168056.LTBP3.png
Soverview

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Protein coding region RNA A-to-I editings for LTBP3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for LTBP3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_824707chr11_65546287_-ENSG00000168056.13ENST00000527339hsa-miR-429065546283655462908mer-1a6554628365546301150.00-19.41
CAediting_824707chr11_65546287_-ENSG00000168056.13ENST00000527339hsa-miR-4667-3p65546285655462917mer-m86554628465546304145.00-17.25

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_824707chr11_65546287_-ENSG00000168056.13ENST00000527339hsa-miR-3667-3p65546285655462917mer-m86554628465546305151-13.99
CAediting_824707chr11_65546287_-ENSG00000168056.13ENST00000527339hsa-miR-429765546283655462908mer-1a6554628365546298145-16.28
CAediting_824707chr11_65546287_-ENSG00000168056.13ENST00000527339hsa-miR-5581-5p65546283655462908mer-1a6554628365546304148-14.7

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1306324chr19_13836464_-ENSG00000168056.13ENST00000528516hsa-miR-27a-3p65543429655434357mer-m86554342865543448171-31.82
CAediting_1306324chr19_13836464_-ENSG00000168056.13ENST00000528516hsa-miR-27a-3p65541154655411618mer-1a6554115465541172152-27.11
CAediting_748296chr10_51299626_+ENSG00000168056.13ENST00000528516hsa-miR-605-3p65539795655398028mer-1a6553979565539816140-15.18
CAediting_1229415chr17_67471547_+ENSG00000168056.13ENST00000322147hsa-miR-548aa65538807655388137mer-m86553880665538830143-11.66
CAediting_1054808chr15_66496985_-ENSG00000168056.13ENST00000528516hsa-miR-451265554244655542507mer-m86555424365554269147-32.55
CAediting_1054808chr15_66496985_-ENSG00000168056.13ENST00000528516hsa-miR-451265552879655528857mer-m86555287865552898158-21.5
CAediting_1368054chr19_46709310_-ENSG00000168056.13ENST00000528516hsa-miR-320e65552312655523187mer-m86555231165552330141-18.76
CAediting_77128chr1_85133844_+ENSG00000168056.13ENST00000528516hsa-miR-4423-3p65546480655464867mer-m86554647965546499140-15.03
CAediting_580943chr7_100356700_+ENSG00000168056.13ENST00000528516hsa-miR-6840-3p65546504655465107mer-m86554650365546525148-25.54
CAediting_1368054chr19_46709310_-ENSG00000168056.13ENST00000528516hsa-miR-320e65539353655393597mer-m86553935265539369141-16.86
CAediting_1054808chr15_66496985_-ENSG00000168056.13ENST00000526825hsa-miR-451265552879655528857mer-m86555287865552898158-21.5
CAediting_1368054chr19_46709310_-ENSG00000168056.13ENST00000526825hsa-miR-320e65552312655523187mer-m86555231165552330141-18.76
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000322147hsa-miR-503-5p65538875655388817mer-m86553887465538896140-18.82
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000530785hsa-miR-503-5p65538875655388817mer-m86553887465538896140-18.82
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000529189hsa-miR-503-5p65538875655388817mer-m86553887465538896140-18.82
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000532932hsa-miR-503-5p65538875655388817mer-m86553887465538896140-18.82
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000528516hsa-miR-503-5p65554203655542097mer-m86555420265554224140-25.61
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000528516hsa-miR-503-5p65552263655522697mer-m86555226265552285148-22.63
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000526825hsa-miR-503-5p65552263655522697mer-m86555226265552285148-22.63

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000528516hsa-miR-503-5p65553727655537337mer-m86555372665553751149-24.97
CAediting_1524209chrX_134546392_-ENSG00000168056.13ENST00000526825hsa-miR-503-5p65553727655537337mer-m86555372665553751149-24.97

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for LTBP3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for LTBP3

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LGGCAediting_824713chr11_65549469_-..0.01168010324566420.315846532333268..
LGGCAediting_824715chr11_65549479_-..0.01458701768679370.272183591941035..
STADCAediting_824715chr11_65549479_-..0.03312823551128540.293176803057166..
STADCAediting_824716chr11_65549480_-..0.03910560725212320.274076135230111..
OVCAediting_824720chr11_65549497_-0.03818552338741340.26182378051016....
STADCAediting_824725chr11_65549514_-0.0181065582364490.312095219473867....
BRCACAediting_824755chr11_65549811_-0.0001430909890746140.317047283687507....
LUADCAediting_824755chr11_65549811_-0.02069708478942510.280100611331429....
BRCACAediting_824760chr11_65549861_-0.01428520614068250.314829201144335....
BRCACAediting_824772chr11_65550165_-0.006651728979025160.319259830321772....
LGGCAediting_824780chr11_65550220_-....0.005220867082224960.239116161897363
BRCACAediting_824802chr11_65550569_-0.00598095426182260.35978215246032....
OVCAediting_824809chr11_65550641_-0.02475254424855760.239276759218081....
LGGCAediting_824821chr11_65550777_-0.001717164848154390.240839366046138....
BRCACAediting_824821chr11_65550777_-7.68810129460282e-050.529496297163022....
OVCAediting_824821chr11_65550777_-0.001449582717949680.348116786497615....
LGGCAediting_824825chr11_65550821_-..0.003054794793698160.281217423975024..

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Relation with cancer stages for LTBP3

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
THCApathologic_stageCAediting_824755chr11_65549811_-0.04587473961868460.195300048799391
THCApathologic_stageCAediting_824821chr11_65550777_-0.005987750969892830.29751571378768

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Relation with survival for LTBP3

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LGGCAediting_824713chr11_65549469_-0.03689625339834630.04203170.000271553
LGGCAediting_824802chr11_65550569_-0.002608722104445290.0240771252.227
LGGCAediting_824819chr11_65550762_-0.00379348770084520.02076570.00550273
OVCAediting_824718chr11_65549488_-0.02312979520957680.005630160.0223397

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RelatedDrugs for LTBP3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for LTBP3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
LTBP3C0002452Amelogenesis Imperfecta2CTD_human;GENOMICS_ENGLAND
LTBP3C0018273Growth Disorders2CTD_human
LTBP3C0020608Hypodontia2CTD_human
LTBP3C0029408Degenerative polyarthritis2CTD_human
LTBP3C0029464Osteosclerosis2CTD_human
LTBP3C0086743Osteoarthrosis Deformans2CTD_human
LTBP3C0376634Craniofacial Abnormalities2CTD_human
LTBP3C0399352Developmental absence of tooth2CTD_human
LTBP3C1832594Verloes Bourguignon syndrome2GENOMICS_ENGLAND;ORPHANET
LTBP3C3489529Tooth Agenesis, Familial2CTD_human
LTBP3C0005940Bone Diseases1CTD_human
LTBP3C0022821Kyphosis deformity of spine1CTD_human
LTBP3C0026267Mitral Valve Prolapse Syndrome1CTD_human
LTBP3C0029410Osteoarthritis of hip1CTD_human
LTBP3C0265287Acromicric Dysplasia1ORPHANET
LTBP3C0432228Brachyolmia1CTD_human
LTBP3C3489726Geleophysic dysplasia1ORPHANET
LTBP3C4540511GELEOPHYSIC DYSPLASIA 31GENOMICS_ENGLAND;UNIPROT