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Editing gene: SPRED3 (CAeditome ID:399473)

Gene summary for SPRED3

Gene summary

Gene information	Gene symbol	SPRED3
	Gene ID	399473
	Gene name	sprouty related EVH1 domain containing 3
	Synonyms	Eve-3\|spred-3
	Cytomap	19q13.2
	Type of gene	protein-coding
	Description	sprouty-related, EVH1 domain-containing protein 3
	Modification date	20210518
	UniProtAcc	Q2MJR0
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for SPRED3

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000188766.11

RNA A-to-I editing events in Cancer.

CAediting_1346599(38392510, +), CAediting_1346600(38397123, +), CAediting_1346601(38397415, +), CAediting_1346602(38397422, +), CAediting_1346603(38397429, +), CAediting_1346604(38397432, +), CAediting_1346605(38397455, +), CAediting_1346606(38397806, +), CAediting_1346607(38397815, +), CAediting_1346608(38397816, +), CAediting_1346609(38397821, +), CAediting_1346610(38397824, +), CAediting_1346611(38397837, +), CAediting_1346612(38397838, +), CAediting_1346613(38397855, +), CAediting_1346614(38397856, +), CAediting_1346615(38397861, +), CAediting_1346616(38397870, +), CAediting_1346617(38397889, +), CAediting_1346618(38398256, +), CAediting_1346619(38398262, +), CAediting_1346620(38398276, +), CAediting_1346621(38398314, +), CAediting_1346622(38398354, +), CAediting_1346623(38398363, +), CAediting_1346624(38398375, +), CAediting_1346625(38398412, +), CAediting_1346626(38398421, +), CAediting_1346627(38398423, +), CAediting_1346628(38398435, +), CAediting_1346629(38398447, +), CAediting_1346630(38398488, +), CAediting_1346631(38398496, +), CAediting_1346632(38398497, +), CAediting_1346633(38398498, +), CAediting_1346634(38398510, +), CAediting_1346635(38398712, +),

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RNA editing positional annotations for SPRED3 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1346599	chr19_38392510_+	ncRNA_exonic
CAediting_1346600	chr19_38397123_+	UTR3
CAediting_1346601	chr19_38397415_+	UTR3
CAediting_1346602	chr19_38397422_+	UTR3
CAediting_1346603	chr19_38397429_+	UTR3
CAediting_1346604	chr19_38397432_+	UTR3
CAediting_1346605	chr19_38397455_+	UTR3
CAediting_1346606	chr19_38397806_+	UTR3
CAediting_1346607	chr19_38397815_+	UTR3
CAediting_1346608	chr19_38397816_+	UTR3
CAediting_1346609	chr19_38397821_+	UTR3
CAediting_1346610	chr19_38397824_+	UTR3
CAediting_1346611	chr19_38397837_+	UTR3
CAediting_1346612	chr19_38397838_+	UTR3
CAediting_1346613	chr19_38397855_+	UTR3
CAediting_1346614	chr19_38397856_+	UTR3
CAediting_1346615	chr19_38397861_+	UTR3
CAediting_1346616	chr19_38397870_+	UTR3
CAediting_1346617	chr19_38397889_+	UTR3
CAediting_1346618	chr19_38398256_+	UTR3
CAediting_1346619	chr19_38398262_+	UTR3
CAediting_1346620	chr19_38398276_+	UTR3
CAediting_1346621	chr19_38398314_+	UTR3
CAediting_1346622	chr19_38398354_+	UTR3
CAediting_1346623	chr19_38398363_+	UTR3
CAediting_1346624	chr19_38398375_+	UTR3
CAediting_1346625	chr19_38398412_+	UTR3
CAediting_1346626	chr19_38398421_+	UTR3
CAediting_1346627	chr19_38398423_+	UTR3
CAediting_1346628	chr19_38398435_+	UTR3
CAediting_1346629	chr19_38398447_+	UTR3
CAediting_1346630	chr19_38398488_+	UTR3
CAediting_1346631	chr19_38398496_+	UTR3
CAediting_1346632	chr19_38398497_+	UTR3
CAediting_1346633	chr19_38398498_+	UTR3
CAediting_1346634	chr19_38398510_+	UTR3
CAediting_1346635	chr19_38398712_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1346599	chr19_38392510_+	LINE	L2	L2a
CAediting_1346606	chr19_38397806_+	SINE	Alu	FLAM_C
CAediting_1346607	chr19_38397815_+	SINE	Alu	FLAM_C
CAediting_1346608	chr19_38397816_+	SINE	Alu	FLAM_C
CAediting_1346609	chr19_38397821_+	SINE	Alu	FLAM_C
CAediting_1346610	chr19_38397824_+	SINE	Alu	FLAM_C
CAediting_1346611	chr19_38397837_+	SINE	Alu	FLAM_C
CAediting_1346612	chr19_38397838_+	SINE	Alu	FLAM_C
CAediting_1346613	chr19_38397855_+	SINE	Alu	FLAM_C
CAediting_1346614	chr19_38397856_+	SINE	Alu	FLAM_C
CAediting_1346615	chr19_38397861_+	SINE	Alu	FLAM_C
CAediting_1346616	chr19_38397870_+	SINE	Alu	FLAM_C
CAediting_1346617	chr19_38397889_+	SINE	Alu	FLAM_C
CAediting_1346618	chr19_38398256_+	SINE	Alu	AluSx3
CAediting_1346619	chr19_38398262_+	SINE	Alu	AluSx3
CAediting_1346620	chr19_38398276_+	SINE	Alu	AluSx3
CAediting_1346621	chr19_38398314_+	SINE	Alu	AluSx3
CAediting_1346622	chr19_38398354_+	SINE	Alu	AluSx3
CAediting_1346623	chr19_38398363_+	SINE	Alu	AluSx3
CAediting_1346624	chr19_38398375_+	SINE	Alu	AluSx3
CAediting_1346625	chr19_38398412_+	SINE	Alu	AluSx3
CAediting_1346626	chr19_38398421_+	SINE	Alu	AluSx3
CAediting_1346627	chr19_38398423_+	SINE	Alu	AluSx3
CAediting_1346628	chr19_38398435_+	SINE	Alu	AluSx3
CAediting_1346629	chr19_38398447_+	SINE	Alu	AluSx3
CAediting_1346630	chr19_38398488_+	SINE	Alu	AluSx3
CAediting_1346631	chr19_38398496_+	SINE	Alu	AluSx3
CAediting_1346632	chr19_38398497_+	SINE	Alu	AluSx3
CAediting_1346633	chr19_38398498_+	SINE	Alu	AluSx3
CAediting_1346634	chr19_38398510_+	SINE	Alu	AluSx3

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RNA A-to-I editing events in the alternative splicing sites for SPRED3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000188766.11.SPRED3.

Correlation between RNA A-to-I editing and PSI for ENSG00000188766.11.SPRED3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SPRED3

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for SPRED3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SPRED3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1346600	chr19_38397123_+	ENSG00000188766.11	ENST00000338502	hsa-miR-328-3p	38397121	38397127	7mer-m8	38397106	38397128	154.00	-19.89
CAediting_1346600	chr19_38397123_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4264	38397116	38397122	7mer-m8	38397106	38397123	141.00	-12.82
CAediting_1346601	chr19_38397415_+	ENSG00000188766.11	ENST00000338502	hsa-miR-1233-3p	38397413	38397420	8mer-1a	38397401	38397420	146.00	-18.91
CAediting_1346601	chr19_38397415_+	ENSG00000188766.11	ENST00000338502	hsa-miR-1233-3p	38397413	38397420	8mer-1a	38397401	38397420	146.00	-18.91
CAediting_1346601	chr19_38397415_+	ENSG00000188766.11	ENST00000338502	hsa-miR-20a-3p	38397408	38397414	7mer-m8	38397395	38397415	143.00	-8.86
CAediting_1346601	chr19_38397415_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3173-5p	38397411	38397417	7mer-m8	38397397	38397418	144.00	-13.43
CAediting_1346601	chr19_38397415_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6779-3p	38397412	38397418	7mer-m8	38397399	38397419	143.00	-13.48
CAediting_1346601	chr19_38397415_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6799-3p	38397411	38397417	7mer-m8	38397393	38397418	155.00	-21.41
CAediting_1346605	chr19_38397455_+	ENSG00000188766.11	ENST00000338502	hsa-miR-378j	38397449	38397454	6mer	38397437	38397455	144.00	-16.90
CAediting_1346607	chr19_38397815_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4457	38397808	38397815	8mer-1a	38397794	38397815	153.00	-21.67
CAediting_1346607	chr19_38397815_+	ENSG00000188766.11	ENST00000338502	hsa-miR-513b-5p	38397809	38397815	7mer-m8	38397794	38397816	162.00	-20.75
CAediting_1346607	chr19_38397815_+	ENSG00000188766.11	ENST00000338502	hsa-miR-638	38397814	38397820	7mer-1a	38397796	38397820	144.00	-27.96
CAediting_1346608	chr19_38397816_+	ENSG00000188766.11	ENST00000338502	hsa-miR-8052	38397814	38397820	7mer-1a	38397801	38397820	153.00	-30.38
CAediting_1346633	chr19_38398498_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3189-3p	38398492	38398498	7mer-m8	38398476	38398499	153.00	-26.36
CAediting_1346633	chr19_38398498_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6813-3p	38398493	38398499	7mer-m8	38398480	38398500	140.00	-11.59
CAediting_1346602	chr19_38397422_+	ENSG00000188766.11	ENST00000338502	hsa-miR-1199-5p	38397415	38397421	7mer-m8	38397403	38397422	140.00	-18.74
CAediting_1346602	chr19_38397422_+	ENSG00000188766.11	ENST00000338502	hsa-miR-1200	38397417	38397423	7mer-m8	38397403	38397424	154.00	-17.56
CAediting_1346602	chr19_38397422_+	ENSG00000188766.11	ENST00000338502	hsa-miR-544b	38397417	38397423	7mer-1a	38397403	38397423	140.00	-19.60
CAediting_1346602	chr19_38397422_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6751-3p	38397415	38397421	7mer-m8	38397402	38397422	145.00	-14.38
CAediting_1346606	chr19_38397806_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3622a-5p	38397804	38397810	7mer-m8	38397792	38397811	149.00	-21.67
CAediting_1346609	chr19_38397821_+	ENSG00000188766.11	ENST00000338502	hsa-miR-371a-3p	38397819	38397825	7mer-m8	38397806	38397826	145.00	-13.97
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-518a-3p	38397821	38397827	7mer-m8	38397807	38397828	145.00	-15.56
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-518a-3p	38397821	38397827	7mer-m8	38397807	38397828	145.00	-15.56
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-518b	38397821	38397827	7mer-m8	38397807	38397828	148.00	-20.11
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-518c-3p	38397821	38397827	7mer-m8	38397806	38397828	148.00	-17.54
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-518d-3p	38397821	38397827	7mer-m8	38397808	38397828	145.00	-15.85
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-518e-3p	38397820	38397826	7mer-m8	38397807	38397827	143.00	-13.23
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-518f-3p	38397821	38397827	7mer-m8	38397808	38397828	145.00	-13.95
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-526a-3p	38397821	38397827	7mer-m8	38397807	38397828	148.00	-16.03
CAediting_1346612	chr19_38397838_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3176	38397831	38397837	7mer-m8	38397820	38397838	140.00	-15.24
CAediting_1346612	chr19_38397838_+	ENSG00000188766.11	ENST00000338502	hsa-miR-331-3p	38397834	38397841	8mer-1a	38397822	38397841	153.00	-25.97
CAediting_1346612	chr19_38397838_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3922-3p	38397831	38397837	7mer-m8	38397817	38397838	141.00	-19.73
CAediting_1346614	chr19_38397856_+	ENSG00000188766.11	ENST00000338502	hsa-miR-18b-3p	38397852	38397858	7mer-m8	38397838	38397859	163.00	-22.51
CAediting_1346614	chr19_38397856_+	ENSG00000188766.11	ENST00000338502	hsa-miR-328-3p	38397854	38397860	7mer-m8	38397840	38397861	152.00	-25.92
CAediting_1346617	chr19_38397889_+	ENSG00000188766.11	ENST00000338502	hsa-miR-197-3p	38397886	38397892	7mer-m8	38397872	38397893	160.00	-20.42
CAediting_1346617	chr19_38397889_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6511a-3p	38397887	38397894	8mer-1a	38397877	38397894	142.00	-16.60
CAediting_1346617	chr19_38397889_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6511a-3p	38397887	38397894	8mer-1a	38397877	38397894	142.00	-16.60
CAediting_1346617	chr19_38397889_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6511a-3p	38397887	38397894	8mer-1a	38397877	38397894	142.00	-16.60
CAediting_1346617	chr19_38397889_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6511a-3p	38397887	38397894	8mer-1a	38397877	38397894	142.00	-16.60
CAediting_1346617	chr19_38397889_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6511b-3p	38397887	38397894	8mer-1a	38397871	38397894	148.00	-21.05
CAediting_1346617	chr19_38397889_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6511b-3p	38397887	38397894	8mer-1a	38397871	38397894	148.00	-21.05
CAediting_1346618	chr19_38398256_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4433b-5p	38398253	38398259	7mer-m8	38398240	38398260	140.00	-10.81
CAediting_1346620	chr19_38398276_+	ENSG00000188766.11	ENST00000338502	hsa-miR-1285-3p	38398275	38398280	6mer	38398260	38398281	148.00	-27.68
CAediting_1346620	chr19_38398276_+	ENSG00000188766.11	ENST00000338502	hsa-miR-1285-3p	38398275	38398280	6mer	38398260	38398281	148.00	-27.68
CAediting_1346620	chr19_38398276_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4486	38398274	38398280	7mer-m8	38398265	38398281	150.00	-20.15
CAediting_1346623	chr19_38398363_+	ENSG00000188766.11	ENST00000338502	hsa-miR-1247-3p	38398357	38398363	7mer-m8	38398342	38398364	151.00	-20.48
CAediting_1346624	chr19_38398375_+	ENSG00000188766.11	ENST00000338502	hsa-miR-215-3p	38398372	38398378	7mer-m8	38398357	38398379	147.00	-16.85
CAediting_1346631	chr19_38398496_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6771-5p	38398490	38398497	8mer-1a	38398478	38398497	160.00	-30.26
CAediting_1346632	chr19_38398497_+	ENSG00000188766.11	ENST00000338502	hsa-miR-326	38398492	38398498	7mer-m8	38398480	38398499	140.00	-13.96
CAediting_1346632	chr19_38398497_+	ENSG00000188766.11	ENST00000338502	hsa-miR-330-5p	38398492	38398498	7mer-m8	38398476	38398499	143.00	-22.58
CAediting_1346632	chr19_38398497_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4314	38398491	38398497	7mer-m8	38398480	38398498	143.00	-24.03
CAediting_1346632	chr19_38398497_+	ENSG00000188766.11	ENST00000338502	hsa-miR-514a-5p	38398493	38398499	7mer-m8	38398477	38398500	150.00	-18.62
CAediting_1346632	chr19_38398497_+	ENSG00000188766.11	ENST00000338502	hsa-miR-514a-5p	38398493	38398499	7mer-m8	38398477	38398500	150.00	-18.62
CAediting_1346632	chr19_38398497_+	ENSG00000188766.11	ENST00000338502	hsa-miR-514a-5p	38398493	38398499	7mer-m8	38398477	38398500	150.00	-18.62
CAediting_1346634	chr19_38398510_+	ENSG00000188766.11	ENST00000338502	hsa-miR-106a-3p	38398506	38398511	6mer	38398491	38398512	141.00	-21.13
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-10a-5p	38398257	38398263	7mer-m8	38398244	38398264	147.00	-15.45
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-10b-5p	38398257	38398263	7mer-m8	38398240	38398264	145.00	-13.30
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-339-5p	38398256	38398262	7mer-m8	38398241	38398263	146.00	-16.43
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4421	38398255	38398261	7mer-m8	38398242	38398262	148.00	-12.07
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4725-5p	38398258	38398264	7mer-m8	38398245	38398265	140.00	-15.96
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-504-5p	38398258	38398264	7mer-m8	38398246	38398265	148.00	-18.15
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-5699-3p	38398255	38398261	7mer-m8	38398241	38398262	141.00	-16.39

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1346620	chr19_38398276_+	ENSG00000188766.11	ENST00000338502	hsa-miR-1262	38398273	38398279	7mer-m8	38398258	38398280	144	-17.39
CAediting_1346602	chr19_38397422_+	ENSG00000188766.11	ENST00000338502	hsa-miR-193a-5p	38397420	38397426	7mer-m8	38397406	38397427	140	-16.33
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-302a-3p	38397820	38397826	7mer-m8	38397805	38397827	141	-11.02
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-302b-3p	38397820	38397826	7mer-m8	38397806	38397827	142	-8.62
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-302c-3p	38397820	38397826	7mer-m8	38397806	38397827	142	-12.39
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-302d-3p	38397820	38397826	7mer-m8	38397806	38397827	146	-9.25
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-302e	38397820	38397826	7mer-m8	38397811	38397827	141	-8.62
CAediting_1346631	chr19_38398496_+	ENSG00000188766.11	ENST00000338502	hsa-miR-30b-3p	38398489	38398496	8mer-1a	38398475	38398496	151	-18.54
CAediting_1346615	chr19_38397861_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3176	38397855	38397861	7mer-m8	38397844	38397862	145	-17.1
CAediting_1346629	chr19_38398447_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3190-5p	38398441	38398447	7mer-m8	38398429	38398448	147	-18.34
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3664-5p	38398257	38398263	7mer-m8	38398243	38398264	153	-17.67
CAediting_1346631	chr19_38398496_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3689a-3p	38398489	38398496	8mer-1a	38398475	38398496	149	-22.05
CAediting_1346631	chr19_38398496_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3689b-3p	38398489	38398496	8mer-1a	38398475	38398496	149	-22.1
CAediting_1346631	chr19_38398496_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3689c	38398489	38398496	8mer-1a	38398475	38398496	149	-22.1
CAediting_1346616	chr19_38397870_+	ENSG00000188766.11	ENST00000338502	hsa-miR-371a-5p	38397864	38397871	8mer-1a	38397852	38397871	150	-18.14
CAediting_1346618	chr19_38398256_+	ENSG00000188766.11	ENST00000338502	hsa-miR-371b-5p	38398250	38398257	8mer-1a	38398236	38398257	142	-7.01
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-372-3p	38397820	38397826	7mer-m8	38397806	38397827	154	-16.15
CAediting_1346618	chr19_38398256_+	ENSG00000188766.11	ENST00000338502	hsa-miR-373-5p	38398250	38398257	8mer-1a	38398236	38398257	148	-11.13
CAediting_1346622	chr19_38398354_+	ENSG00000188766.11	ENST00000338502	hsa-miR-3929	38398351	38398357	7mer-m8	38398337	38398358	148	-21.12
CAediting_1346604	chr19_38397432_+	ENSG00000188766.11	ENST00000338502	hsa-miR-409-3p	38397429	38397435	7mer-m8	38397415	38397436	146	-10.24
CAediting_1346612	chr19_38397838_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4287	38397836	38397842	7mer-m8	38397825	38397843	145	-19.49
CAediting_1346635	chr19_38398712_+	ENSG00000188766.11	ENST00000338502	hsa-miR-431-5p	38398708	38398715	8mer-1a	38398691	38398715	146	-20.05
CAediting_1346622	chr19_38398354_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4478	38398351	38398357	7mer-m8	38398341	38398358	150	-22.79
CAediting_1346630	chr19_38398488_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4478	38398485	38398491	7mer-m8	38398477	38398492	149	-22.24
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4522	38398258	38398264	7mer-m8	38398245	38398265	148	-13.26
CAediting_1346622	chr19_38398354_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4649-3p	38398348	38398354	7mer-m8	38398335	38398355	140	-13.06
CAediting_1346630	chr19_38398488_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4649-3p	38398482	38398488	7mer-m8	38398469	38398489	140	-14.63
CAediting_1346612	chr19_38397838_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4685-3p	38397836	38397842	7mer-m8	38397820	38397843	149	-24.98
CAediting_1346625	chr19_38398412_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4698	38398411	38398417	7mer-1a	38398395	38398417	144	-13.53
CAediting_1346620	chr19_38398276_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4701-3p	38398273	38398279	7mer-m8	38398260	38398280	153	-19.98
CAediting_1346630	chr19_38398488_+	ENSG00000188766.11	ENST00000338502	hsa-miR-485-5p	38398486	38398492	7mer-m8	38398472	38398493	149	-16.01
CAediting_1346608	chr19_38397816_+	ENSG00000188766.11	ENST00000338502	hsa-miR-5089-5p	38397814	38397820	7mer-m8	38397801	38397821	148	-13.72
CAediting_1346609	chr19_38397821_+	ENSG00000188766.11	ENST00000338502	hsa-miR-5089-5p	38397814	38397820	7mer-m8	38397801	38397821	148	-13.72
CAediting_1346609	chr19_38397821_+	ENSG00000188766.11	ENST00000338502	hsa-miR-512-3p	38397819	38397825	7mer-m8	38397806	38397826	154	-17.89
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-512-3p	38397819	38397825	7mer-m8	38397806	38397826	154	-17.89
CAediting_1346609	chr19_38397821_+	ENSG00000188766.11	ENST00000338502	hsa-miR-512-3p	38397819	38397825	7mer-m8	38397806	38397826	154	-17.89
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-512-3p	38397819	38397825	7mer-m8	38397806	38397826	154	-17.89
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-519d-3p	38397821	38397827	7mer-m8	38397808	38397828	142	-12.88
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-520a-3p	38397820	38397826	7mer-m8	38397806	38397827	140	-10.49
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-520b-3p	38397820	38397826	7mer-m8	38397807	38397827	143	-17
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-520c-3p	38397820	38397826	7mer-m8	38397806	38397827	148	-17
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-520d-3p	38397820	38397826	7mer-m8	38397806	38397827	140	-13.67
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-520e-3p	38397820	38397826	7mer-m8	38397807	38397827	147	-15.16
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-520g-3p	38397822	38397828	7mer-m8	38397806	38397829	153	-14.49
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-520h	38397822	38397828	7mer-m8	38397808	38397829	150	-13.4
CAediting_1346610	chr19_38397824_+	ENSG00000188766.11	ENST00000338502	hsa-miR-526b-3p	38397821	38397827	7mer-m8	38397807	38397828	148	-14.98
CAediting_1346602	chr19_38397422_+	ENSG00000188766.11	ENST00000338502	hsa-miR-526b-5p	38397417	38397423	7mer-m8	38397402	38397424	150	-10.8
CAediting_1346629	chr19_38398447_+	ENSG00000188766.11	ENST00000338502	hsa-miR-548s	38398440	38398446	7mer-m8	38398423	38398447	143	-15.64
CAediting_1346618	chr19_38398256_+	ENSG00000188766.11	ENST00000338502	hsa-miR-616-5p	38398250	38398257	8mer-1a	38398236	38398257	147	-6.8
CAediting_1346611	chr19_38397837_+	ENSG00000188766.11	ENST00000338502	hsa-miR-623	38397835	38397841	7mer-m8	38397816	38397842	144	-25.15
CAediting_1346612	chr19_38397838_+	ENSG00000188766.11	ENST00000338502	hsa-miR-623	38397835	38397841	7mer-m8	38397816	38397842	144	-25.15
CAediting_1346607	chr19_38397815_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6504-3p	38397811	38397816	6mer	38397795	38397817	140	-14.55
CAediting_1346608	chr19_38397816_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6504-3p	38397811	38397816	6mer	38397795	38397817	140	-14.55
CAediting_1346609	chr19_38397821_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6506-5p	38397815	38397821	7mer-m8	38397800	38397822	150	-16.33
CAediting_1346620	chr19_38398276_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6736-5p	38398273	38398279	7mer-m8	38398261	38398280	141	-20.03
CAediting_1346630	chr19_38398488_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6765-5p	38398482	38398487	6mer	38398461	38398488	142	-25.45
CAediting_1346620	chr19_38398276_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6776-5p	38398274	38398280	7mer-m8	38398260	38398281	151	-27.19
CAediting_1346631	chr19_38398496_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6779-5p	38398489	38398496	8mer-1a	38398478	38398496	148	-23.1
CAediting_1346606	chr19_38397806_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6807-5p	38397799	38397805	7mer-m8	38397785	38397806	147	-16.36
CAediting_1346627	chr19_38398423_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6818-3p	38398420	38398426	7mer-m8	38398407	38398427	146	-15.69
CAediting_1346601	chr19_38397415_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6841-3p	38397410	38397416	7mer-m8	38397397	38397417	152	-16.23
CAediting_1346616	chr19_38397870_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6843-3p	38397868	38397874	7mer-m8	38397856	38397875	152	-20.01
CAediting_1346616	chr19_38397870_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6848-3p	38397868	38397874	7mer-m8	38397858	38397875	142	-15.32
CAediting_1346611	chr19_38397837_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6878-3p	38397830	38397837	8mer-1a	38397817	38397837	142	-14.14
CAediting_1346619	chr19_38398262_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6888-3p	38398255	38398261	7mer-m8	38398242	38398262	151	-14.42
CAediting_1346622	chr19_38398354_+	ENSG00000188766.11	ENST00000338502	hsa-miR-7160-5p	38398349	38398355	7mer-m8	38398338	38398356	144	-19.09
CAediting_1346630	chr19_38398488_+	ENSG00000188766.11	ENST00000338502	hsa-miR-7160-5p	38398483	38398489	7mer-m8	38398468	38398490	145	-19.94
CAediting_1346621	chr19_38398314_+	ENSG00000188766.11	ENST00000338502	hsa-miR-7855-5p	38398307	38398313	7mer-m8	38398293	38398314	140	-12.54
CAediting_1346631	chr19_38398496_+	ENSG00000188766.11	ENST00000338502	hsa-miR-887-5p	38398490	38398497	8mer-1a	38398478	38398497	143	-15.14
CAediting_1346632	chr19_38398497_+	ENSG00000188766.11	ENST00000338502	hsa-miR-887-5p	38398490	38398497	8mer-1a	38398478	38398497	143	-15.14

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000188766.11	ENST00000338502	hsa-miR-605-3p	38398058	38398065	8mer-1a	38398044	38398065	151	-19.81
CAediting_393	chr1_1167164_+	ENSG00000188766.11	ENST00000338502	hsa-miR-200b-3p	38397957	38397963	7mer-m8	38397940	38397964	151	-19.51
CAediting_1054808	chr15_66496985_-	ENSG00000188766.11	ENST00000338502	hsa-miR-4512	38397646	38397652	7mer-m8	38397634	38397653	147	-13.73
CAediting_1160181	chr17_7017644_-	ENSG00000188766.11	ENST00000338502	hsa-miR-195-3p	38397430	38397436	7mer-m8	38397416	38397437	145	-16.27
CAediting_1368054	chr19_46709310_-	ENSG00000188766.11	ENST00000338502	hsa-miR-320e	38397279	38397285	7mer-m8	38397269	38397286	147	-17.16
CAediting_1368054	chr19_46709310_-	ENSG00000188766.11	ENST00000338502	hsa-miR-320e	38398959	38398965	7mer-m8	38398949	38398966	158	-24.95
CAediting_86358	chr1_109598906_+	ENSG00000188766.11	ENST00000338502	hsa-miR-197-5p	38397033	38397040	8mer-1a	38397018	38397040	140	-22.12
CAediting_77128	chr1_85133844_+	ENSG00000188766.11	ENST00000338502	hsa-miR-4423-3p	38396803	38396809	7mer-m8	38396790	38396810	147	-13.08
CAediting_1399425	chr20_1392958_-	ENSG00000188766.11	ENST00000338502	hsa-miR-6869-5p	38397242	38397248	7mer-m8	38397228	38397249	146	-18.66
CAediting_1399425	chr20_1392958_-	ENSG00000188766.11	ENST00000338502	hsa-miR-6869-5p	38398791	38398796	6mer	38398776	38398797	142	-17.9
CAediting_1399425	chr20_1392958_-	ENSG00000188766.11	ENST00000338502	hsa-miR-6869-5p	38396789	38396795	7mer-m8	38396772	38396796	155	-26.88
CAediting_228905	chr2_188297554_+	ENSG00000188766.11	ENST00000338502	hsa-miR-561-3p	38396745	38396751	7mer-m8	38396728	38396752	159	-17.09
CAediting_396018	chr5_1062918_-	ENSG00000188766.11	ENST00000338502	hsa-miR-4635	38398693	38398699	7mer-m8	38398680	38398700	146	-22.18
CAediting_580943	chr7_100356700_+	ENSG00000188766.11	ENST00000338502	hsa-miR-6840-3p	38398325	38398331	7mer-m8	38398311	38398332	140	-23.09
CAediting_604450	chr7_133034877_-	ENSG00000188766.11	ENST00000338502	hsa-miR-3654	38397277	38397283	7mer-m8	38397266	38397284	140	-17.39
CAediting_524911	chr7_5495852_-	ENSG00000188766.11	ENST00000338502	hsa-miR-589-3p	38396756	38396762	7mer-m8	38396739	38396763	154	-16.16
CAediting_524911	chr7_5495852_-	ENSG00000188766.11	ENST00000338502	hsa-miR-589-3p	38396998	38397004	7mer-m8	38396982	38397005	140	-15.5
CAediting_468389	chr6_31355314_-	ENSG00000188766.11	ENST00000586958	hsa-miR-6891-5p	38394659	38394664	6mer	38394650	38394668	146	-20.41
CAediting_468389	chr6_31355314_-	ENSG00000188766.11	ENST00000586958	hsa-miR-6891-5p	38394661	38394667	7mer-m8	38394650	38394668	146	-20.41

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_573000	chr7_92204081_-	ENSG00000188766.11	ENST00000338502	hsa-miR-1285-5p	38398882	38398888	7mer-m8	38398870	38398889	142	-15.72
CAediting_573001	chr7_92204086_-	ENSG00000188766.11	ENST00000338502	hsa-miR-1285-5p	38398882	38398888	7mer-m8	38398870	38398889	142	-15.72
CAediting_1160181	chr17_7017644_-	ENSG00000188766.11	ENST00000338502	hsa-miR-195-3p	38399466	38399472	7mer-m8	38399451	38399473	147	-10.64
CAediting_1368054	chr19_46709310_-	ENSG00000188766.11	ENST00000338502	hsa-miR-320e	38396326	38396332	7mer-m8	38396315	38396333	149	-16.88
CAediting_396018	chr5_1062918_-	ENSG00000188766.11	ENST00000338502	hsa-miR-4635	38398143	38398149	7mer-m8	38398130	38398150	144	-11.83
CAediting_228905	chr2_188297554_+	ENSG00000188766.11	ENST00000338502	hsa-miR-561-3p	38398085	38398091	7mer-m8	38398071	38398092	140	-7.3
CAediting_980496	chr14_31014685_-	ENSG00000188766.11	ENST00000338502	hsa-miR-624-3p	38397808	38397814	7mer-1a	38397793	38397814	140	-14

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for SPRED3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for SPRED3

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_1346600	chr19_38397123_+	0.00473684796109144	0.341063199794242	.	.	.	.
PCPG	CAediting_1346600	chr19_38397123_+	0.00780917529122287	0.327172259374383	.	.	.	.
LGG	CAediting_1346601	chr19_38397415_+	0.0144108983101475	0.19193842663741	0.000453989145080909	0.272380464441024	.	.
BRCA	CAediting_1346601	chr19_38397415_+	1.24878576941538e-09	0.435403145934573	.	.	.	.
LUAD	CAediting_1346601	chr19_38397415_+	0.0221045264004038	0.316843959823485	.	.	.	.
GBM	CAediting_1346601	chr19_38397415_+	1.38357167860462e-06	0.45290294456793	.	.	.	.
ESCA	CAediting_1346601	chr19_38397415_+	0.00394734293067385	0.396735938458634	.	.	.	.
OV	CAediting_1346601	chr19_38397415_+	0.0317925378295453	0.208708340755342	.	.	.	.
PCPG	CAediting_1346601	chr19_38397415_+	1.76810607335173e-08	0.527048893056752	0.0251274019593518	0.223907505354329	.	.
SKCM	CAediting_1346601	chr19_38397415_+	2.927538700084e-07	0.601634265072048	.	.	.	.
SKCM	CAediting_1346608	chr19_38397816_+	1.61983568459492e-05	0.484426280212945	.	.	.	.
SKCM	CAediting_1346628	chr19_38398435_+	0.0372013866231476	0.284307181736259	.	.	.	.
GBM	CAediting_1346630	chr19_38398488_+	0.00142937368944605	0.281118194728302	.	.	.	.
GBM	CAediting_1346633	chr19_38398498_+	0.000443181036036936	0.301483335849181	.	.	.	.
GBM	CAediting_1346634	chr19_38398510_+	6.75969174232213e-08	0.537312442223321	.	.	.	.
LGG	CAediting_1346635	chr19_38398712_+	.	.	0.000349641623110794	0.337806207534484	.	.
PCPG	CAediting_1346635	chr19_38398712_+	7.24991924410659e-06	0.401474440610144	.	.	.	.

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Relation with cancer stages for SPRED3

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for SPRED3

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for SPRED3

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SPRED3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene