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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: LDHA (CAeditome ID:3939)

Gene summary for LDHA

check button Gene summary
Gene informationGene symbol

LDHA

Gene ID

3939

Gene namelactate dehydrogenase A
SynonymsGSD11|HEL-S-133P|LDHM|PIG19
Cytomap

11p15.1

Type of geneprotein-coding
DescriptionL-lactate dehydrogenase A chainLDH muscle subunitLDH-ALDH-Mcell proliferation-inducing gene 19 proteinepididymis secretory sperm binding protein Li 133Plactate dehydrogenase Mproliferation-inducing gene 19renal carcinoma antigen NY-REN-59
Modification date20210518
UniProtAcc

P00338

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for LDHA

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000134333.12

check button RNA A-to-I editing events in Cancer.
CAediting_801619(18397540, +), CAediting_801620(18397623, +), CAediting_801621(18397639, +), CAediting_801622(18397732, +), CAediting_801623(18397771, +), CAediting_801624(18397793, +), CAediting_801625(18398419, +), CAediting_801626(18398575, +), CAediting_801627(18398636, +), CAediting_801628(18398662, +), CAediting_801629(18398799, +), CAediting_801630(18398821, +), CAediting_801631(18398874, +), CAediting_801632(18398875, +), CAediting_801633(18398876, +), CAediting_801634(18398970, +), CAediting_801635(18398971, +), CAediting_801636(18398980, +), CAediting_801637(18398983, +), CAediting_801638(18399737, +), CAediting_801639(18399860, +), CAediting_801640(18402223, +), CAediting_801641(18402351, +), CAediting_801642(18403950, +), CAediting_801643(18403954, +), CAediting_801644(18403957, +), CAediting_801645(18403986, +), CAediting_801646(18403994, +), CAediting_801647(18403995, +), CAediting_801648(18404005, +), CAediting_801649(18404030, +), CAediting_801650(18404035, +), CAediting_801651(18404048, +), CAediting_801652(18404070, +), CAediting_801653(18404072, +), CAediting_801654(18404076, +), CAediting_801655(18404096, +), CAediting_801656(18404097, +), CAediting_801657(18404106, +), CAediting_801658(18404112, +), CAediting_801659(18404115, +), CAediting_801660(18404244, +), CAediting_801661(18404246, +), CAediting_801662(18404250, +), CAediting_801663(18404251, +), CAediting_801664(18404262, +), CAediting_801665(18404266, +), CAediting_801666(18404303, +), CAediting_801667(18404305, +), CAediting_801668(18404311, +), CAediting_801669(18404315, +), CAediting_801670(18404318, +), CAediting_801671(18404329, +), CAediting_801672(18404342, +), CAediting_801673(18404343, +), CAediting_801674(18404354, +), CAediting_801675(18404355, +), CAediting_801676(18404403, +), CAediting_801677(18404421, +), CAediting_801678(18404554, +), CAediting_801679(18404642, +), CAediting_801680(18404645, +), CAediting_801681(18404646, +), CAediting_801682(18404648, +), CAediting_801683(18404651, +), CAediting_801684(18404661, +), CAediting_801685(18404693, +), CAediting_801686(18404714, +), CAediting_801687(18404758, +), CAediting_801688(18404760, +), CAediting_801689(18405988, +), CAediting_801690(18405992, +), CAediting_801691(18406006, +), CAediting_801692(18406046, +), CAediting_801693(18406059, +), CAediting_801694(18406066, +), CAediting_801695(18406070, +), CAediting_801696(18406092, +), CAediting_801697(18406095, +), CAediting_801698(18406105, +), CAediting_801699(18406107, +), CAediting_801700(18406140, +), CAediting_801701(18406146, +), CAediting_801702(18406149, +), CAediting_801703(18406163, +), CAediting_801704(18406168, +), CAediting_801705(18406188, +), CAediting_801706(18406348, +), CAediting_801707(18406386, +), CAediting_801708(18406440, +), CAediting_801709(18406450, +), CAediting_801710(18406464, +), CAediting_801711(18406469, +), CAediting_801712(18406485, +), CAediting_801713(18406486, +), CAediting_801714(18406507, +), CAediting_801715(18406510, +), CAediting_801716(18406516, +), CAediting_801717(18406521, +), CAediting_801718(18406527, +), CAediting_801719(18406530, +), CAediting_801720(18406531, +), CAediting_801721(18406533, +), CAediting_801722(18406539, +), CAediting_801723(18406540, +), CAediting_801724(18406541, +), CAediting_801725(18406552, +), CAediting_801726(18406555, +), CAediting_801727(18406556, +), CAediting_801728(18406557, +), CAediting_801729(18406558, +), CAediting_801730(18406559, +), CAediting_801731(18406561, +), CAediting_801732(18406569, +), CAediting_801733(18406573, +), CAediting_801734(18406596, +), CAediting_801735(18406601, +), CAediting_801736(18406605, +), CAediting_801737(18406625, +), CAediting_801738(18406631, +), CAediting_801739(18406641, +), CAediting_801740(18406668, +), CAediting_801741(18406719, +), CAediting_801742(18406720, +), CAediting_801743(18406805, +), CAediting_801744(18406818, +), CAediting_801745(18406819, +), CAediting_801746(18406830, +), CAediting_801747(18406836, +), CAediting_801748(18406837, +), CAediting_801749(18406838, +), CAediting_801750(18406858, +), CAediting_801751(18406862, +), CAediting_801752(18406863, +), CAediting_801753(18406864, +), CAediting_801754(18406867, +), CAediting_801755(18406871, +), CAediting_801756(18406885, +), CAediting_801757(18406893, +), CAediting_801758(18406912, +), CAediting_801759(18406921, +), CAediting_801760(18406934, +), CAediting_801761(18406951, +), CAediting_801762(18406958, +), CAediting_801763(18407784, +),

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RNA editing positional annotations for LDHA using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_801619chr11_18397540_+ncRNA_intronic
CAediting_801620chr11_18397623_+ncRNA_intronic
CAediting_801621chr11_18397639_+ncRNA_intronic
CAediting_801622chr11_18397732_+ncRNA_intronic
CAediting_801623chr11_18397771_+ncRNA_intronic
CAediting_801624chr11_18397793_+ncRNA_intronic
CAediting_801625chr11_18398419_+ncRNA_intronic
CAediting_801626chr11_18398575_+ncRNA_intronic
CAediting_801627chr11_18398636_+ncRNA_exonic
CAediting_801628chr11_18398662_+ncRNA_exonic
CAediting_801629chr11_18398799_+exonic
CAediting_801630chr11_18398821_+ncRNA_exonic
CAediting_801631chr11_18398874_+ncRNA_exonic
CAediting_801632chr11_18398875_+ncRNA_exonic
CAediting_801633chr11_18398876_+ncRNA_exonic
CAediting_801634chr11_18398970_+ncRNA_exonic
CAediting_801635chr11_18398971_+ncRNA_exonic
CAediting_801636chr11_18398980_+ncRNA_exonic
CAediting_801637chr11_18398983_+ncRNA_exonic
CAediting_801638chr11_18399737_+ncRNA_exonic
CAediting_801639chr11_18399860_+ncRNA_exonic
CAediting_801640chr11_18402223_+ncRNA_intronic
CAediting_801641chr11_18402351_+ncRNA_intronic
CAediting_801642chr11_18403950_+ncRNA_intronic
CAediting_801643chr11_18403954_+ncRNA_intronic
CAediting_801644chr11_18403957_+ncRNA_intronic
CAediting_801645chr11_18403986_+ncRNA_intronic
CAediting_801646chr11_18403994_+ncRNA_intronic
CAediting_801647chr11_18403995_+ncRNA_intronic
CAediting_801648chr11_18404005_+ncRNA_intronic
CAediting_801649chr11_18404030_+ncRNA_intronic
CAediting_801650chr11_18404035_+ncRNA_intronic
CAediting_801651chr11_18404048_+ncRNA_intronic
CAediting_801652chr11_18404070_+ncRNA_intronic
CAediting_801653chr11_18404072_+ncRNA_intronic
CAediting_801654chr11_18404076_+ncRNA_intronic
CAediting_801655chr11_18404096_+ncRNA_intronic
CAediting_801656chr11_18404097_+ncRNA_intronic
CAediting_801657chr11_18404106_+ncRNA_intronic
CAediting_801658chr11_18404112_+ncRNA_intronic
CAediting_801659chr11_18404115_+ncRNA_intronic
CAediting_801660chr11_18404244_+ncRNA_intronic
CAediting_801661chr11_18404246_+ncRNA_intronic
CAediting_801662chr11_18404250_+ncRNA_intronic
CAediting_801663chr11_18404251_+ncRNA_intronic
CAediting_801664chr11_18404262_+ncRNA_intronic
CAediting_801665chr11_18404266_+ncRNA_intronic
CAediting_801666chr11_18404303_+ncRNA_intronic
CAediting_801667chr11_18404305_+ncRNA_intronic
CAediting_801668chr11_18404311_+ncRNA_intronic
CAediting_801669chr11_18404315_+ncRNA_intronic
CAediting_801670chr11_18404318_+ncRNA_intronic
CAediting_801671chr11_18404329_+ncRNA_intronic
CAediting_801672chr11_18404342_+ncRNA_intronic
CAediting_801673chr11_18404343_+ncRNA_intronic
CAediting_801674chr11_18404354_+ncRNA_intronic
CAediting_801675chr11_18404355_+ncRNA_intronic
CAediting_801676chr11_18404403_+ncRNA_intronic
CAediting_801677chr11_18404421_+ncRNA_intronic
CAediting_801678chr11_18404554_+ncRNA_intronic
CAediting_801679chr11_18404642_+ncRNA_intronic
CAediting_801680chr11_18404645_+ncRNA_intronic
CAediting_801681chr11_18404646_+ncRNA_intronic
CAediting_801682chr11_18404648_+ncRNA_intronic
CAediting_801683chr11_18404651_+ncRNA_intronic
CAediting_801684chr11_18404661_+ncRNA_intronic
CAediting_801685chr11_18404693_+ncRNA_intronic
CAediting_801686chr11_18404714_+ncRNA_intronic
CAediting_801687chr11_18404758_+ncRNA_intronic
CAediting_801688chr11_18404760_+ncRNA_intronic
CAediting_801689chr11_18405988_+ncRNA_intronic
CAediting_801690chr11_18405992_+ncRNA_intronic
CAediting_801691chr11_18406006_+ncRNA_intronic
CAediting_801692chr11_18406046_+ncRNA_intronic
CAediting_801693chr11_18406059_+ncRNA_intronic
CAediting_801694chr11_18406066_+ncRNA_intronic
CAediting_801695chr11_18406070_+ncRNA_intronic
CAediting_801696chr11_18406092_+ncRNA_intronic
CAediting_801697chr11_18406095_+ncRNA_intronic
CAediting_801698chr11_18406105_+ncRNA_intronic
CAediting_801699chr11_18406107_+ncRNA_intronic
CAediting_801700chr11_18406140_+ncRNA_intronic
CAediting_801701chr11_18406146_+ncRNA_intronic
CAediting_801702chr11_18406149_+ncRNA_intronic
CAediting_801703chr11_18406163_+ncRNA_intronic
CAediting_801704chr11_18406168_+ncRNA_intronic
CAediting_801705chr11_18406188_+ncRNA_intronic
CAediting_801706chr11_18406348_+ncRNA_intronic
CAediting_801707chr11_18406386_+ncRNA_intronic
CAediting_801708chr11_18406440_+ncRNA_intronic
CAediting_801709chr11_18406450_+ncRNA_intronic
CAediting_801710chr11_18406464_+ncRNA_intronic
CAediting_801711chr11_18406469_+ncRNA_intronic
CAediting_801712chr11_18406485_+ncRNA_intronic
CAediting_801713chr11_18406486_+ncRNA_intronic
CAediting_801714chr11_18406507_+ncRNA_intronic
CAediting_801715chr11_18406510_+ncRNA_intronic
CAediting_801716chr11_18406516_+ncRNA_intronic
CAediting_801717chr11_18406521_+ncRNA_intronic
CAediting_801718chr11_18406527_+ncRNA_intronic
CAediting_801719chr11_18406530_+ncRNA_intronic
CAediting_801720chr11_18406531_+ncRNA_intronic
CAediting_801721chr11_18406533_+ncRNA_intronic
CAediting_801722chr11_18406539_+ncRNA_intronic
CAediting_801723chr11_18406540_+ncRNA_intronic
CAediting_801724chr11_18406541_+ncRNA_intronic
CAediting_801725chr11_18406552_+ncRNA_intronic
CAediting_801726chr11_18406555_+ncRNA_intronic
CAediting_801727chr11_18406556_+ncRNA_intronic
CAediting_801728chr11_18406557_+ncRNA_intronic
CAediting_801729chr11_18406558_+ncRNA_intronic
CAediting_801730chr11_18406559_+ncRNA_intronic
CAediting_801731chr11_18406561_+ncRNA_intronic
CAediting_801732chr11_18406569_+ncRNA_intronic
CAediting_801733chr11_18406573_+ncRNA_intronic
CAediting_801734chr11_18406596_+ncRNA_intronic
CAediting_801735chr11_18406601_+ncRNA_intronic
CAediting_801736chr11_18406605_+ncRNA_intronic
CAediting_801737chr11_18406625_+ncRNA_intronic
CAediting_801738chr11_18406631_+ncRNA_intronic
CAediting_801739chr11_18406641_+ncRNA_intronic
CAediting_801740chr11_18406668_+ncRNA_exonic
CAediting_801741chr11_18406719_+ncRNA_exonic
CAediting_801742chr11_18406720_+ncRNA_exonic
CAediting_801743chr11_18406805_+ncRNA_intronic
CAediting_801744chr11_18406818_+ncRNA_intronic
CAediting_801745chr11_18406819_+ncRNA_intronic
CAediting_801746chr11_18406830_+ncRNA_intronic
CAediting_801747chr11_18406836_+ncRNA_intronic
CAediting_801748chr11_18406837_+ncRNA_intronic
CAediting_801749chr11_18406838_+ncRNA_intronic
CAediting_801750chr11_18406858_+ncRNA_intronic
CAediting_801751chr11_18406862_+ncRNA_intronic
CAediting_801752chr11_18406863_+ncRNA_intronic
CAediting_801753chr11_18406864_+ncRNA_intronic
CAediting_801754chr11_18406867_+ncRNA_intronic
CAediting_801755chr11_18406871_+ncRNA_intronic
CAediting_801756chr11_18406885_+ncRNA_intronic
CAediting_801757chr11_18406893_+ncRNA_intronic
CAediting_801758chr11_18406912_+ncRNA_intronic
CAediting_801759chr11_18406921_+ncRNA_intronic
CAediting_801760chr11_18406934_+ncRNA_intronic
CAediting_801761chr11_18406951_+ncRNA_intronic
CAediting_801762chr11_18406958_+ncRNA_intronic
CAediting_801763chr11_18407784_+UTR3

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_801619chr11_18397540_+SINEAluAluSc8
CAediting_801620chr11_18397623_+SINEAluAluSc8
CAediting_801621chr11_18397639_+SINEAluAluSc8
CAediting_801622chr11_18397732_+SINEAluAluSc8
CAediting_801623chr11_18397771_+SINEAluAluSc8
CAediting_801624chr11_18397793_+SINEAluAluSc8
CAediting_801625chr11_18398419_+SINEAluAluSx1
CAediting_801626chr11_18398575_+SINEAluAluSx1
CAediting_801627chr11_18398636_+SINEAluAluY
CAediting_801628chr11_18398662_+SINEAluAluY
CAediting_801629chr11_18398799_+SINEAluAluY
CAediting_801630chr11_18398821_+SINEAluAluY
CAediting_801631chr11_18398874_+SINEAluAluY
CAediting_801632chr11_18398875_+SINEAluAluY
CAediting_801633chr11_18398876_+SINEAluAluY
CAediting_801634chr11_18398970_+SINEAluAluSx1
CAediting_801635chr11_18398971_+SINEAluAluSx1
CAediting_801636chr11_18398980_+SINEAluAluSx1
CAediting_801637chr11_18398983_+SINEAluAluSx1
CAediting_801638chr11_18399737_+SINEAluAluJo
CAediting_801639chr11_18399860_+SINEAluAluJo
CAediting_801640chr11_18402223_+SINEAluAluSx
CAediting_801641chr11_18402351_+SINEAluAluJr4
CAediting_801642chr11_18403950_+SINEAluAluSc8
CAediting_801643chr11_18403954_+SINEAluAluSc8
CAediting_801644chr11_18403957_+SINEAluAluSc8
CAediting_801645chr11_18403986_+SINEAluAluSc8
CAediting_801646chr11_18403994_+SINEAluAluSc8
CAediting_801647chr11_18403995_+SINEAluAluSc8
CAediting_801648chr11_18404005_+SINEAluAluSc8
CAediting_801649chr11_18404030_+SINEAluAluSc8
CAediting_801650chr11_18404035_+SINEAluAluSc8
CAediting_801651chr11_18404048_+SINEAluAluSc8
CAediting_801652chr11_18404070_+SINEAluAluSc8
CAediting_801653chr11_18404072_+SINEAluAluSc8
CAediting_801654chr11_18404076_+SINEAluAluSc8
CAediting_801655chr11_18404096_+SINEAluAluSc8
CAediting_801656chr11_18404097_+SINEAluAluSc8
CAediting_801657chr11_18404106_+SINEAluAluSc8
CAediting_801658chr11_18404112_+SINEAluAluSc8
CAediting_801659chr11_18404115_+SINEAluAluSc8
CAediting_801660chr11_18404244_+SINEAluAluJb
CAediting_801661chr11_18404246_+SINEAluAluJb
CAediting_801662chr11_18404250_+SINEAluAluJb
CAediting_801663chr11_18404251_+SINEAluAluJb
CAediting_801664chr11_18404262_+SINEAluAluJb
CAediting_801665chr11_18404266_+SINEAluAluJb
CAediting_801666chr11_18404303_+SINEAluAluJb
CAediting_801667chr11_18404305_+SINEAluAluJb
CAediting_801668chr11_18404311_+SINEAluAluJb
CAediting_801669chr11_18404315_+SINEAluAluJb
CAediting_801670chr11_18404318_+SINEAluAluJb
CAediting_801671chr11_18404329_+SINEAluAluJb
CAediting_801672chr11_18404342_+SINEAluAluJb
CAediting_801673chr11_18404343_+SINEAluAluJb
CAediting_801674chr11_18404354_+SINEAluAluJb
CAediting_801675chr11_18404355_+SINEAluAluJb
CAediting_801676chr11_18404403_+SINEAluAluJb
CAediting_801677chr11_18404421_+SINEAluAluJb
CAediting_801678chr11_18404554_+SINEAluAluY
CAediting_801679chr11_18404642_+SINEAluAluY
CAediting_801680chr11_18404645_+SINEAluAluY
CAediting_801681chr11_18404646_+SINEAluAluY
CAediting_801682chr11_18404648_+SINEAluAluY
CAediting_801683chr11_18404651_+SINEAluAluY
CAediting_801684chr11_18404661_+SINEAluAluY
CAediting_801685chr11_18404693_+SINEAluAluY
CAediting_801686chr11_18404714_+SINEAluAluY
CAediting_801687chr11_18404758_+SINEAluAluY
CAediting_801688chr11_18404760_+SINEAluAluY
CAediting_801689chr11_18405988_+SINEAluAluSx4
CAediting_801690chr11_18405992_+SINEAluAluSx4
CAediting_801691chr11_18406006_+SINEAluAluSx4
CAediting_801692chr11_18406046_+SINEAluAluSx4
CAediting_801693chr11_18406059_+SINEAluAluSx4
CAediting_801694chr11_18406066_+SINEAluAluSx4
CAediting_801695chr11_18406070_+SINEAluAluSx4
CAediting_801696chr11_18406092_+SINEAluAluSx4
CAediting_801697chr11_18406095_+SINEAluAluSx4
CAediting_801698chr11_18406105_+SINEAluAluSx4
CAediting_801699chr11_18406107_+SINEAluAluSx4
CAediting_801700chr11_18406140_+SINEAluAluSx4
CAediting_801701chr11_18406146_+SINEAluAluSx4
CAediting_801702chr11_18406149_+SINEAluAluSx4
CAediting_801703chr11_18406163_+SINEAluAluSx4
CAediting_801704chr11_18406168_+SINEAluAluSx4
CAediting_801705chr11_18406188_+SINEAluAluSx4
CAediting_801706chr11_18406348_+SINEAluFLAM_C
CAediting_801707chr11_18406386_+SINEAluFLAM_C
CAediting_801708chr11_18406440_+SINEAluAluSq2
CAediting_801709chr11_18406450_+SINEAluAluSq2
CAediting_801710chr11_18406464_+SINEAluAluSq2
CAediting_801711chr11_18406469_+SINEAluAluSq2
CAediting_801712chr11_18406485_+SINEAluAluSq2
CAediting_801713chr11_18406486_+SINEAluAluSq2
CAediting_801714chr11_18406507_+SINEAluAluSq2
CAediting_801715chr11_18406510_+SINEAluAluSq2
CAediting_801716chr11_18406516_+SINEAluAluSq2
CAediting_801717chr11_18406521_+SINEAluAluSq2
CAediting_801718chr11_18406527_+SINEAluAluSq2
CAediting_801719chr11_18406530_+SINEAluAluSq2
CAediting_801720chr11_18406531_+SINEAluAluSq2
CAediting_801721chr11_18406533_+SINEAluAluSq2
CAediting_801722chr11_18406539_+SINEAluAluSq2
CAediting_801723chr11_18406540_+SINEAluAluSq2
CAediting_801724chr11_18406541_+SINEAluAluSq2
CAediting_801725chr11_18406552_+SINEAluAluSq2
CAediting_801726chr11_18406555_+SINEAluAluSq2
CAediting_801727chr11_18406556_+SINEAluAluSq2
CAediting_801728chr11_18406557_+SINEAluAluSq2
CAediting_801729chr11_18406558_+SINEAluAluSq2
CAediting_801730chr11_18406559_+SINEAluAluSq2
CAediting_801731chr11_18406561_+SINEAluAluSq2
CAediting_801732chr11_18406569_+SINEAluAluSq2
CAediting_801733chr11_18406573_+SINEAluAluSq2
CAediting_801734chr11_18406596_+SINEAluAluSq2
CAediting_801735chr11_18406601_+SINEAluAluSq2
CAediting_801736chr11_18406605_+SINEAluAluSq2
CAediting_801737chr11_18406625_+SINEAluAluSq2
CAediting_801738chr11_18406631_+SINEAluAluSq2
CAediting_801739chr11_18406641_+SINEAluAluSq2
CAediting_801740chr11_18406668_+SINEAluAluSq2
CAediting_801741chr11_18406719_+SINEAluAluSq2
CAediting_801742chr11_18406720_+SINEAluAluSq2
CAediting_801743chr11_18406805_+SINEAluAluSx
CAediting_801744chr11_18406818_+SINEAluAluSx
CAediting_801745chr11_18406819_+SINEAluAluSx
CAediting_801746chr11_18406830_+SINEAluAluSx
CAediting_801747chr11_18406836_+SINEAluAluSx
CAediting_801748chr11_18406837_+SINEAluAluSx
CAediting_801749chr11_18406838_+SINEAluAluSx
CAediting_801750chr11_18406858_+SINEAluAluSx
CAediting_801751chr11_18406862_+SINEAluAluSx
CAediting_801752chr11_18406863_+SINEAluAluSx
CAediting_801753chr11_18406864_+SINEAluAluSx
CAediting_801754chr11_18406867_+SINEAluAluSx
CAediting_801755chr11_18406871_+SINEAluAluSx
CAediting_801756chr11_18406885_+SINEAluAluSx
CAediting_801757chr11_18406893_+SINEAluAluSx
CAediting_801758chr11_18406912_+SINEAluAluSx
CAediting_801759chr11_18406921_+SINEAluAluSx
CAediting_801760chr11_18406934_+SINEAluAluSx
CAediting_801761chr11_18406951_+SINEAluAluSx
CAediting_801762chr11_18406958_+SINEAluAluSx

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RNA A-to-I editing events in the alternative splicing sites for LDHA

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_801629chr11_18398799_+18398777:183987993SS3+0iCTAAATGTTTGTATTTTTTAGTA-8.49CTAAATGTTTGTATTTTTTAGTG-8.42
ESCAediting_801629chr11_18398799_+18398780:183988023SS0+1iAATGTTTGTATTTTTTAGTAGAG-16.12AATGTTTGTATTTTTTAGTGGAG-7.37

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000134333.12.LDHA.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000134333.12.LDHA.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LDHA

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for LDHA

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for LDHA

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_801630chr11_18398821_+ENSG00000134333.12ENST00000545467hsa-miR-3190-5p18398819183988257mer-m81839880718398826147.00-18.34
CAediting_801630chr11_18398821_+ENSG00000134333.12ENST00000545467hsa-miR-548s18398818183988247mer-m81839880418398825143.00-12.53
CAediting_801631chr11_18398874_+ENSG00000134333.12ENST00000545467hsa-miR-6771-5p18398868183988758mer-1a1839885418398875159.00-29.20
CAediting_801632chr11_18398875_+ENSG00000134333.12ENST00000545467hsa-miR-3192-5p18398868183988758mer-1a1839885218398875156.00-30.56
CAediting_801632chr11_18398875_+ENSG00000134333.12ENST00000545467hsa-miR-32618398870183988767mer-m81839885818398877140.00-14.14
CAediting_801632chr11_18398875_+ENSG00000134333.12ENST00000545467hsa-miR-330-5p18398870183988767mer-m81839885618398877140.00-21.79
CAediting_801632chr11_18398875_+ENSG00000134333.12ENST00000545467hsa-miR-431418398869183988757mer-m81839885918398876140.00-18.80
CAediting_801632chr11_18398875_+ENSG00000134333.12ENST00000545467hsa-miR-514a-5p18398871183988777mer-m81839885818398878154.00-19.31
CAediting_801632chr11_18398875_+ENSG00000134333.12ENST00000545467hsa-miR-514a-5p18398871183988777mer-m81839885818398878154.00-19.31
CAediting_801632chr11_18398875_+ENSG00000134333.12ENST00000545467hsa-miR-514a-5p18398871183988777mer-m81839885818398878154.00-19.31
CAediting_801633chr11_18398876_+ENSG00000134333.12ENST00000545467hsa-miR-3189-3p18398870183988767mer-m81839885818398877145.00-22.91
CAediting_801633chr11_18398876_+ENSG00000134333.12ENST00000545467hsa-miR-6813-3p18398871183988777mer-m81839885818398878140.00-14.31
CAediting_801634chr11_18398970_+ENSG00000134333.12ENST00000545467hsa-miR-3192-5p18398963183989708mer-1a1839894818398970158.00-30.90
CAediting_801634chr11_18398970_+ENSG00000134333.12ENST00000545467hsa-miR-32618398965183989717mer-m81839895318398972140.00-15.12
CAediting_801634chr11_18398970_+ENSG00000134333.12ENST00000545467hsa-miR-330-5p18398965183989717mer-m81839895118398972140.00-21.22
CAediting_801634chr11_18398970_+ENSG00000134333.12ENST00000545467hsa-miR-431418398964183989707mer-m81839895418398971140.00-21.17
CAediting_801634chr11_18398970_+ENSG00000134333.12ENST00000545467hsa-miR-514a-5p18398966183989727mer-m81839895018398973146.00-20.07
CAediting_801634chr11_18398970_+ENSG00000134333.12ENST00000545467hsa-miR-514a-5p18398966183989727mer-m81839895018398973146.00-20.07
CAediting_801634chr11_18398970_+ENSG00000134333.12ENST00000545467hsa-miR-514a-5p18398966183989727mer-m81839895018398973146.00-20.07
CAediting_801635chr11_18398971_+ENSG00000134333.12ENST00000545467hsa-miR-3189-3p18398965183989717mer-m81839895018398972149.00-25.05
CAediting_801635chr11_18398971_+ENSG00000134333.12ENST00000545467hsa-miR-6813-3p18398966183989727mer-m81839895318398973140.00-12.55
CAediting_801636chr11_18398980_+ENSG00000134333.12ENST00000545467hsa-miR-6793-3p18398973183989797mer-m81839896118398980144.00-15.79

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_801630chr11_18398821_+ENSG00000134333.12ENST00000545467hsa-miR-3064-5p18398820183988256mer1839880618398826148-24.74
CAediting_801630chr11_18398821_+ENSG00000134333.12ENST00000545467hsa-miR-3085-3p18398820183988256mer1839880618398826142-21.75
CAediting_801631chr11_18398874_+ENSG00000134333.12ENST00000545467hsa-miR-30b-3p18398867183988748mer-1a1839885318398874151-15.97
CAediting_801630chr11_18398821_+ENSG00000134333.12ENST00000545467hsa-miR-314318398815183988206mer1839880018398821140-12.33
CAediting_801637chr11_18398983_+ENSG00000134333.12ENST00000545467hsa-miR-368618398980183989867mer-m81839896618398987140-11.63
CAediting_801631chr11_18398874_+ENSG00000134333.12ENST00000545467hsa-miR-3689a-3p18398867183988748mer-1a1839885218398874142-19.06
CAediting_801631chr11_18398874_+ENSG00000134333.12ENST00000545467hsa-miR-3689b-3p18398867183988748mer-1a1839885218398874142-19.11
CAediting_801631chr11_18398874_+ENSG00000134333.12ENST00000545467hsa-miR-3689c18398867183988748mer-1a1839885218398874142-19.11
CAediting_801636chr11_18398980_+ENSG00000134333.12ENST00000545467hsa-miR-4733-5p18398974183989807mer-m81839896018398981152-16.58
CAediting_801630chr11_18398821_+ENSG00000134333.12ENST00000545467hsa-miR-479418398819183988257mer-m81839880418398826151-18.19
CAediting_801630chr11_18398821_+ENSG00000134333.12ENST00000545467hsa-miR-664a-5p18398819183988257mer-m81839880318398826141-15.8
CAediting_801631chr11_18398874_+ENSG00000134333.12ENST00000545467hsa-miR-6779-5p18398867183988748mer-1a1839885518398874146-21.8
CAediting_801634chr11_18398970_+ENSG00000134333.12ENST00000545467hsa-miR-887-5p18398963183989708mer-1a1839895018398970147-13.82
CAediting_801631chr11_18398874_+ENSG00000134333.12ENST00000545467hsa-miR-887-5p18398868183988758mer-1a1839885418398875154-16.65
CAediting_801632chr11_18398875_+ENSG00000134333.12ENST00000545467hsa-miR-887-5p18398868183988758mer-1a1839885418398875154-16.65

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_396018chr5_1062918_-ENSG00000134333.12ENST00000545467hsa-miR-463518398938183989447mer-m81839892518398945162-21.35
CAediting_442554chr5_154685830_+ENSG00000134333.12ENST00000545467hsa-miR-130318399495183995017mer-m81839947918399502147-18.59
CAediting_228905chr2_188297554_+ENSG00000134333.12ENST00000539814hsa-miR-561-3p18400725184007328mer-1a1840071318400732147-8.86
CAediting_604450chr7_133034877_-ENSG00000134333.12ENST00000539814hsa-miR-365418400919184009257mer-m81840090718400926156-19.03
CAediting_1351755chr19_40282625_-ENSG00000134333.12ENST00000543695hsa-miR-64118403724184037296mer1840370718403730140-16.55
CAediting_1351755chr19_40282625_-ENSG00000134333.12ENST00000536528hsa-miR-64118403724184037296mer1840370718403730140-16.55
CAediting_604450chr7_133034877_-ENSG00000134333.12ENST00000545215hsa-miR-365418400919184009257mer-m81840090718400926156-19.03
CAediting_1351755chr19_40282625_-ENSG00000134333.12ENST00000545215hsa-miR-64118403724184037296mer1840370718403730140-16.55
CAediting_604450chr7_133034877_-ENSG00000134333.12ENST00000486690hsa-miR-365418400919184009257mer-m81840090718400926156-19.03
CAediting_1351755chr19_40282625_-ENSG00000134333.12ENST00000486690hsa-miR-64118403724184037296mer1840370718403730140-16.55

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for LDHA

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for LDHA

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for LDHA

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for LDHA

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for LDHA

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
LDHAP00338DB09118StiripentolL-lactate dehydrogenase A chain SmallMoleculeDrugapproved
LDHAP00338DB02701NicotinamideL-lactate dehydrogenase A chain SmallMoleculeDrugapproved|investigational
LDHAP00338DB09130CopperL-lactate dehydrogenase A chain SmallMoleculeDrugapproved|investigational
LDHAP00338DB00157NADHL-lactate dehydrogenase A chain SmallMoleculeDrugapproved|nutraceutical

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RelatedDiseases for LDHA

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
LDHAC2931743Lactate dehydrogenase deficiency type A3CTD_human;GENOMICS_ENGLAND;ORPHANET
LDHAC0017919Glycogen Storage Disease2GENOMICS_ENGLAND
LDHAC0005586Bipolar Disorder1PSYGENET
LDHAC0011570Mental Depression1PSYGENET
LDHAC0027051Myocardial Infarction1CTD_human
LDHAC0027080Myoglobinuria1CTD_human
LDHAC0030297Pancreatic Neoplasm1CTD_human
LDHAC0033141Cardiomyopathies, Primary1CTD_human
LDHAC0036529Myocardial Diseases, Secondary1CTD_human
LDHAC0041696Unipolar Depression1PSYGENET
LDHAC0152013Adenocarcinoma of lung (disorder)1CTD_human
LDHAC0346647Malignant neoplasm of pancreas1CTD_human
LDHAC0525045Mood Disorders1PSYGENET
LDHAC0878544Cardiomyopathies1CTD_human
LDHAC1269683Major Depressive Disorder1PSYGENET