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Editing gene: IYD (CAeditome ID:389434)

Gene summary for IYD

Gene summary

Gene information	Gene symbol	IYD
	Gene ID	389434
	Gene name	iodotyrosine deiodinase
	Synonyms	C6orf71\|DEHAL1\|IYD-1\|TDH4
	Cytomap	6q25.1
	Type of gene	protein-coding
	Description	iodotyrosine deiodinase 1iodotyrosine dehalogenase 1
	Modification date	20210518
	UniProtAcc	Q6PHW0
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
IYD	GO:0010181	Iodotyrosine deiodinase 1	25395621
IYD	GO:0140616	Iodotyrosine deiodinase 1	15289438
IYD	GO:0140616	Iodotyrosine deiodinase 1	25395621
IYD	GO:0006570	Iodotyrosine deiodinase 1	25395621
IYD	GO:0042403	Iodotyrosine deiodinase 1	25395621
IYD	GO:0005654	Iodotyrosine deiodinase 1	0000052
IYD	GO:0005886	Iodotyrosine deiodinase 1	0000052
IYD	GO:0005887	Iodotyrosine deiodinase 1	15289438
IYD	GO:0030659	Iodotyrosine deiodinase 1	15289438

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RNA A-to-I events for IYD

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000009765.13

RNA A-to-I editing events in Cancer.

CAediting_510648(150371251, +), CAediting_510649(150379876, +), CAediting_510650(150379881, +), CAediting_510651(150379890, +), CAediting_510652(150379891, +), CAediting_510653(150387319, +), CAediting_510654(150388802, +), CAediting_510655(150389022, +), CAediting_510656(150390977, +), CAediting_510657(150390983, +), CAediting_510658(150390984, +), CAediting_510659(150391014, +), CAediting_510660(150391028, +), CAediting_510661(150391038, +), CAediting_510662(150391051, +), CAediting_510663(150391053, +), CAediting_510664(150391072, +), CAediting_510665(150391081, +), CAediting_510666(150391085, +), CAediting_510667(150391086, +), CAediting_510668(150391087, +), CAediting_510669(150391106, +), CAediting_510670(150391116, +), CAediting_510671(150391126, +), CAediting_510672(150391146, +), CAediting_510673(150391148, +), CAediting_510674(150391149, +), CAediting_510675(150391158, +), CAediting_510676(150391172, +), CAediting_510677(150391207, +), CAediting_510678(150391809, +), CAediting_510679(150391810, +), CAediting_510680(150391834, +), CAediting_510681(150391838, +), CAediting_510682(150391848, +), CAediting_510683(150391850, +), CAediting_510684(150391858, +), CAediting_510685(150391875, +), CAediting_510686(150391883, +), CAediting_510687(150391898, +), CAediting_510688(150392070, +), CAediting_510689(150392086, +), CAediting_510690(150392089, +), CAediting_510691(150392128, +), CAediting_510692(150392129, +), CAediting_510693(150392132, +), CAediting_510694(150392133, +), CAediting_510695(150392141, +), CAediting_510696(150392154, +), CAediting_510697(150392158, +), CAediting_510698(150394852, +), CAediting_510699(150394898, +), CAediting_510700(150394945, +), CAediting_510701(150394955, +), CAediting_510702(150394957, +), CAediting_510703(150395008, +), CAediting_510704(150395025, +), CAediting_510705(150395037, +), CAediting_510706(150395043, +), CAediting_510707(150395057, +), CAediting_510708(150395065, +), CAediting_510709(150395084, +), CAediting_510710(150395096, +), CAediting_510711(150395104, +), CAediting_510712(150396858, +), CAediting_510713(150397295, +), CAediting_510714(150397305, +), CAediting_510715(150397307, +), CAediting_510716(150397313, +), CAediting_510717(150397353, +), CAediting_510718(150397373, +), CAediting_510719(150397374, +), CAediting_510720(150397414, +), CAediting_510721(150397416, +), CAediting_510722(150397417, +), CAediting_510723(150397431, +), CAediting_510724(150397447, +), CAediting_510725(150397449, +), CAediting_510726(150397459, +), CAediting_510727(150397463, +), CAediting_510728(150397466, +), CAediting_510729(150397472, +), CAediting_510730(150397490, +), CAediting_510731(150397495, +), CAediting_510732(150397509, +), CAediting_510733(150398786, +), CAediting_510734(150398787, +), CAediting_510735(150398809, +), CAediting_510736(150398886, +), CAediting_510737(150398928, +), CAediting_510738(150398941, +), CAediting_510739(150398942, +), CAediting_510740(150398955, +), CAediting_510741(150398956, +), CAediting_510742(150399022, +), CAediting_510743(150400287, +), CAediting_510744(150400291, +), CAediting_510745(150402967, +), CAediting_510746(150402976, +), CAediting_510747(150402979, +), CAediting_510748(150402997, +), CAediting_510749(150403002, +), CAediting_510750(150403007, +), CAediting_510751(150403014, +), CAediting_510752(150403027, +), CAediting_510753(150403040, +), CAediting_510754(150403053, +), CAediting_510755(150403057, +),

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RNA editing positional annotations for IYD using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_510648	chr6_150371251_+	ncRNA_intronic
CAediting_510649	chr6_150379876_+	ncRNA_intronic
CAediting_510650	chr6_150379881_+	ncRNA_intronic
CAediting_510651	chr6_150379890_+	ncRNA_intronic
CAediting_510652	chr6_150379891_+	ncRNA_intronic
CAediting_510653	chr6_150387319_+	ncRNA_intronic
CAediting_510654	chr6_150388802_+	ncRNA_intronic
CAediting_510655	chr6_150389022_+	ncRNA_intronic
CAediting_510656	chr6_150390977_+	intronic
CAediting_510657	chr6_150390983_+	intronic
CAediting_510658	chr6_150390984_+	intronic
CAediting_510659	chr6_150391014_+	intronic
CAediting_510660	chr6_150391028_+	intronic
CAediting_510661	chr6_150391038_+	intronic
CAediting_510662	chr6_150391051_+	intronic
CAediting_510663	chr6_150391053_+	intronic
CAediting_510664	chr6_150391072_+	intronic
CAediting_510665	chr6_150391081_+	intronic
CAediting_510666	chr6_150391085_+	intronic
CAediting_510667	chr6_150391086_+	intronic
CAediting_510668	chr6_150391087_+	intronic
CAediting_510669	chr6_150391106_+	intronic
CAediting_510670	chr6_150391116_+	intronic
CAediting_510671	chr6_150391126_+	intronic
CAediting_510672	chr6_150391146_+	intronic
CAediting_510673	chr6_150391148_+	intronic
CAediting_510674	chr6_150391149_+	intronic
CAediting_510675	chr6_150391158_+	intronic
CAediting_510676	chr6_150391172_+	intronic
CAediting_510677	chr6_150391207_+	intronic
CAediting_510678	chr6_150391809_+	intronic
CAediting_510679	chr6_150391810_+	intronic
CAediting_510680	chr6_150391834_+	intronic
CAediting_510681	chr6_150391838_+	intronic
CAediting_510682	chr6_150391848_+	intronic
CAediting_510683	chr6_150391850_+	intronic
CAediting_510684	chr6_150391858_+	intronic
CAediting_510685	chr6_150391875_+	intronic
CAediting_510686	chr6_150391883_+	intronic
CAediting_510687	chr6_150391898_+	intronic
CAediting_510688	chr6_150392070_+	intronic
CAediting_510689	chr6_150392086_+	intronic
CAediting_510690	chr6_150392089_+	intronic
CAediting_510691	chr6_150392128_+	intronic
CAediting_510692	chr6_150392129_+	intronic
CAediting_510693	chr6_150392132_+	intronic
CAediting_510694	chr6_150392133_+	intronic
CAediting_510695	chr6_150392141_+	intronic
CAediting_510696	chr6_150392154_+	intronic
CAediting_510697	chr6_150392158_+	intronic
CAediting_510698	chr6_150394852_+	intronic
CAediting_510699	chr6_150394898_+	intronic
CAediting_510700	chr6_150394945_+	intronic
CAediting_510701	chr6_150394955_+	intronic
CAediting_510702	chr6_150394957_+	intronic
CAediting_510703	chr6_150395008_+	intronic
CAediting_510704	chr6_150395025_+	intronic
CAediting_510705	chr6_150395037_+	intronic
CAediting_510706	chr6_150395043_+	intronic
CAediting_510707	chr6_150395057_+	intronic
CAediting_510708	chr6_150395065_+	intronic
CAediting_510709	chr6_150395084_+	intronic
CAediting_510710	chr6_150395096_+	intronic
CAediting_510711	chr6_150395104_+	intronic
CAediting_510712	chr6_150396858_+	UTR3
CAediting_510713	chr6_150397295_+	intronic
CAediting_510714	chr6_150397305_+	intronic
CAediting_510715	chr6_150397307_+	intronic
CAediting_510716	chr6_150397313_+	intronic
CAediting_510717	chr6_150397353_+	intronic
CAediting_510718	chr6_150397373_+	intronic
CAediting_510719	chr6_150397374_+	intronic
CAediting_510720	chr6_150397414_+	intronic
CAediting_510721	chr6_150397416_+	intronic
CAediting_510722	chr6_150397417_+	intronic
CAediting_510723	chr6_150397431_+	intronic
CAediting_510724	chr6_150397447_+	intronic
CAediting_510725	chr6_150397449_+	intronic
CAediting_510726	chr6_150397459_+	intronic
CAediting_510727	chr6_150397463_+	intronic
CAediting_510728	chr6_150397466_+	intronic
CAediting_510729	chr6_150397472_+	intronic
CAediting_510730	chr6_150397490_+	intronic
CAediting_510731	chr6_150397495_+	intronic
CAediting_510732	chr6_150397509_+	intronic
CAediting_510733	chr6_150398786_+	UTR3
CAediting_510734	chr6_150398787_+	UTR3
CAediting_510735	chr6_150398809_+	UTR3
CAediting_510736	chr6_150398886_+	UTR3
CAediting_510737	chr6_150398928_+	UTR3
CAediting_510738	chr6_150398941_+	UTR3
CAediting_510739	chr6_150398942_+	UTR3
CAediting_510740	chr6_150398955_+	UTR3
CAediting_510741	chr6_150398956_+	UTR3
CAediting_510742	chr6_150399022_+	UTR3
CAediting_510743	chr6_150400287_+	UTR3
CAediting_510744	chr6_150400291_+	UTR3
CAediting_510745	chr6_150402967_+	UTR3
CAediting_510746	chr6_150402976_+	UTR3
CAediting_510747	chr6_150402979_+	UTR3
CAediting_510748	chr6_150402997_+	UTR3
CAediting_510749	chr6_150403002_+	UTR3
CAediting_510750	chr6_150403007_+	UTR3
CAediting_510751	chr6_150403014_+	UTR3
CAediting_510752	chr6_150403027_+	UTR3
CAediting_510753	chr6_150403040_+	UTR3
CAediting_510754	chr6_150403053_+	UTR3
CAediting_510755	chr6_150403057_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_510648	chr6_150371251_+	SINE	MIR	MIR
CAediting_510649	chr6_150379876_+	LTR	ERV1	LTR48B
CAediting_510650	chr6_150379881_+	LTR	ERV1	LTR48B
CAediting_510651	chr6_150379890_+	LTR	ERV1	LTR48B
CAediting_510652	chr6_150379891_+	LTR	ERV1	LTR48B
CAediting_510653	chr6_150387319_+	SINE	Alu	FLAM_A
CAediting_510654	chr6_150388802_+	SINE	Alu	AluSz
CAediting_510655	chr6_150389022_+	SINE	Alu	FRAM
CAediting_510656	chr6_150390977_+	SINE	Alu	AluSc
CAediting_510657	chr6_150390983_+	SINE	Alu	AluSc
CAediting_510658	chr6_150390984_+	SINE	Alu	AluSc
CAediting_510659	chr6_150391014_+	SINE	Alu	AluSc
CAediting_510660	chr6_150391028_+	SINE	Alu	AluSc
CAediting_510661	chr6_150391038_+	SINE	Alu	AluSc
CAediting_510662	chr6_150391051_+	SINE	Alu	AluSc
CAediting_510663	chr6_150391053_+	SINE	Alu	AluSc
CAediting_510664	chr6_150391072_+	SINE	Alu	AluSc
CAediting_510665	chr6_150391081_+	SINE	Alu	AluSc
CAediting_510666	chr6_150391085_+	SINE	Alu	AluSc
CAediting_510667	chr6_150391086_+	SINE	Alu	AluSc
CAediting_510668	chr6_150391087_+	SINE	Alu	AluSc
CAediting_510669	chr6_150391106_+	SINE	Alu	AluSc
CAediting_510670	chr6_150391116_+	SINE	Alu	AluSc
CAediting_510671	chr6_150391126_+	SINE	Alu	AluSc
CAediting_510672	chr6_150391146_+	SINE	Alu	AluSc
CAediting_510673	chr6_150391148_+	SINE	Alu	AluSc
CAediting_510674	chr6_150391149_+	SINE	Alu	AluSc
CAediting_510675	chr6_150391158_+	SINE	Alu	AluSc
CAediting_510676	chr6_150391172_+	SINE	Alu	AluSc
CAediting_510677	chr6_150391207_+	SINE	Alu	AluSc
CAediting_510678	chr6_150391809_+	SINE	Alu	AluSq2
CAediting_510679	chr6_150391810_+	SINE	Alu	AluSq2
CAediting_510680	chr6_150391834_+	SINE	Alu	AluSq2
CAediting_510681	chr6_150391838_+	SINE	Alu	AluSq2
CAediting_510682	chr6_150391848_+	SINE	Alu	AluSq2
CAediting_510683	chr6_150391850_+	SINE	Alu	AluSq2
CAediting_510684	chr6_150391858_+	SINE	Alu	AluSq2
CAediting_510685	chr6_150391875_+	SINE	Alu	AluSq2
CAediting_510686	chr6_150391883_+	SINE	Alu	AluSq2
CAediting_510687	chr6_150391898_+	SINE	Alu	AluSq2
CAediting_510688	chr6_150392070_+	SINE	Alu	AluJb
CAediting_510689	chr6_150392086_+	SINE	Alu	AluJb
CAediting_510690	chr6_150392089_+	SINE	Alu	AluJb
CAediting_510691	chr6_150392128_+	SINE	Alu	AluJb
CAediting_510692	chr6_150392129_+	SINE	Alu	AluJb
CAediting_510693	chr6_150392132_+	SINE	Alu	AluJb
CAediting_510694	chr6_150392133_+	SINE	Alu	AluJb
CAediting_510695	chr6_150392141_+	SINE	Alu	AluJb
CAediting_510696	chr6_150392154_+	SINE	Alu	AluJb
CAediting_510697	chr6_150392158_+	SINE	Alu	AluJb
CAediting_510698	chr6_150394852_+	SINE	Alu	AluJb
CAediting_510699	chr6_150394898_+	SINE	Alu	AluJb
CAediting_510700	chr6_150394945_+	SINE	Alu	AluJb
CAediting_510701	chr6_150394955_+	SINE	Alu	AluJb
CAediting_510702	chr6_150394957_+	SINE	Alu	AluJb
CAediting_510703	chr6_150395008_+	SINE	Alu	AluJb
CAediting_510704	chr6_150395025_+	SINE	Alu	AluJb
CAediting_510705	chr6_150395037_+	SINE	Alu	AluJb
CAediting_510706	chr6_150395043_+	SINE	Alu	AluJb
CAediting_510707	chr6_150395057_+	SINE	Alu	AluJb
CAediting_510708	chr6_150395065_+	SINE	Alu	AluJb
CAediting_510709	chr6_150395084_+	SINE	Alu	AluJb
CAediting_510710	chr6_150395096_+	SINE	Alu	AluJb
CAediting_510711	chr6_150395104_+	SINE	Alu	AluJb
CAediting_510712	chr6_150396858_+	SINE	Alu	AluY
CAediting_510713	chr6_150397295_+	SINE	Alu	AluJb
CAediting_510714	chr6_150397305_+	SINE	Alu	AluJb
CAediting_510715	chr6_150397307_+	SINE	Alu	AluJb
CAediting_510716	chr6_150397313_+	SINE	Alu	AluJb
CAediting_510717	chr6_150397353_+	SINE	Alu	AluJb
CAediting_510718	chr6_150397373_+	SINE	Alu	AluJb
CAediting_510719	chr6_150397374_+	SINE	Alu	AluJb
CAediting_510720	chr6_150397414_+	SINE	Alu	AluJb
CAediting_510721	chr6_150397416_+	SINE	Alu	AluJb
CAediting_510722	chr6_150397417_+	SINE	Alu	AluJb
CAediting_510723	chr6_150397431_+	SINE	Alu	AluJb
CAediting_510724	chr6_150397447_+	SINE	Alu	AluJb
CAediting_510725	chr6_150397449_+	SINE	Alu	AluJb
CAediting_510726	chr6_150397459_+	SINE	Alu	AluJb
CAediting_510727	chr6_150397463_+	SINE	Alu	AluJb
CAediting_510728	chr6_150397466_+	SINE	Alu	AluJb
CAediting_510729	chr6_150397472_+	SINE	Alu	AluJb
CAediting_510730	chr6_150397490_+	SINE	Alu	AluJb
CAediting_510731	chr6_150397495_+	SINE	Alu	AluJb
CAediting_510732	chr6_150397509_+	SINE	Alu	AluJb
CAediting_510733	chr6_150398786_+	SINE	Alu	AluSx
CAediting_510734	chr6_150398787_+	SINE	Alu	AluSx
CAediting_510735	chr6_150398809_+	SINE	Alu	AluSx
CAediting_510736	chr6_150398886_+	SINE	Alu	AluSx
CAediting_510737	chr6_150398928_+	SINE	Alu	AluSx
CAediting_510738	chr6_150398941_+	SINE	Alu	AluSx
CAediting_510739	chr6_150398942_+	SINE	Alu	AluSx
CAediting_510740	chr6_150398955_+	SINE	Alu	AluSx
CAediting_510741	chr6_150398956_+	SINE	Alu	AluSx
CAediting_510742	chr6_150399022_+	SINE	Alu	AluSx
CAediting_510745	chr6_150402967_+	SINE	Alu	AluJr
CAediting_510746	chr6_150402976_+	SINE	Alu	AluJr
CAediting_510747	chr6_150402979_+	SINE	Alu	AluJr
CAediting_510748	chr6_150402997_+	SINE	Alu	AluJr
CAediting_510749	chr6_150403002_+	SINE	Alu	AluJr
CAediting_510750	chr6_150403007_+	SINE	Alu	AluJr
CAediting_510751	chr6_150403014_+	SINE	Alu	AluJr
CAediting_510752	chr6_150403027_+	SINE	Alu	AluJr
CAediting_510753	chr6_150403040_+	SINE	Alu	AluJr
CAediting_510754	chr6_150403053_+	SINE	Alu	AluJr
CAediting_510755	chr6_150403057_+	SINE	Alu	AluJr

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RNA A-to-I editing events in the alternative splicing sites for IYD

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000009765.13.IYD.

Correlation between RNA A-to-I editing and PSI for ENSG00000009765.13.IYD.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for IYD

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

THCA.CAediting_510740.ENSG00000009765.IYD.png
Soverview

THCA.CAediting_510741.ENSG00000009765.IYD.png
Soverview

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Protein coding region RNA A-to-I editings for IYD

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for IYD

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_510740	chr6_150398955_+	ENSG00000009765.13	ENST00000229447	hsa-miR-127-3p	150398953	150398959	7mer-m8	150398939	150398960	141.00	-20.03
CAediting_510740	chr6_150398955_+	ENSG00000009765.13	ENST00000344419	hsa-miR-127-3p	150398953	150398959	7mer-m8	150398939	150398960	141.00	-20.03
CAediting_510744	chr6_150400291_+	ENSG00000009765.13	ENST00000229447	hsa-miR-549a-3p	150400286	150400292	7mer-m8	150400274	150400293	145.00	-14.63
CAediting_510744	chr6_150400291_+	ENSG00000009765.13	ENST00000344419	hsa-miR-549a-3p	150400286	150400292	7mer-m8	150400274	150400293	145.00	-14.63
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1228-5p	150402965	150402970	6mer	150402949	150402971	142.00	-22.98
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1285-3p	150402966	150402971	6mer	150402951	150402972	147.00	-22.25
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1285-3p	150402966	150402971	6mer	150402951	150402972	147.00	-22.25
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4486	150402965	150402971	7mer-m8	150402956	150402972	145.00	-19.61
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1228-5p	150402965	150402970	6mer	150402949	150402971	142.00	-22.98
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1285-3p	150402966	150402971	6mer	150402951	150402972	147.00	-22.25
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1285-3p	150402966	150402971	6mer	150402951	150402972	147.00	-22.25
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4486	150402965	150402971	7mer-m8	150402956	150402972	145.00	-19.61
CAediting_510746	chr6_150402976_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6512-3p	150402971	150402978	8mer-1a	150402957	150402978	142.00	-19.53
CAediting_510746	chr6_150402976_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6720-5p	150402971	150402978	8mer-1a	150402957	150402978	152.00	-27.54
CAediting_510746	chr6_150402976_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6849-3p	150402970	150402977	8mer-1a	150402956	150402977	152.00	-18.04
CAediting_510746	chr6_150402976_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6512-3p	150402971	150402978	8mer-1a	150402957	150402978	142.00	-19.53
CAediting_510746	chr6_150402976_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6720-5p	150402971	150402978	8mer-1a	150402957	150402978	152.00	-27.54
CAediting_510746	chr6_150402976_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6849-3p	150402970	150402977	8mer-1a	150402956	150402977	152.00	-18.04
CAediting_510712	chr6_150396858_+	ENSG00000009765.13	ENST00000500320	hsa-miR-339-5p	150396852	150396858	7mer-m8	150396837	150396859	163.00	-27.29
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000229447	hsa-miR-513a-5p	150398780	150398786	7mer-m8	150398770	150398787	152.00	-17.32
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000229447	hsa-miR-513a-5p	150398780	150398786	7mer-m8	150398770	150398787	152.00	-17.32
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000229447	hsa-miR-638	150398785	150398791	7mer-1a	150398765	150398791	154.00	-31.53
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000344419	hsa-miR-513a-5p	150398780	150398786	7mer-m8	150398770	150398787	152.00	-17.32
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000344419	hsa-miR-513a-5p	150398780	150398786	7mer-m8	150398770	150398787	152.00	-17.32
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000344419	hsa-miR-638	150398785	150398791	7mer-1a	150398765	150398791	154.00	-31.53
CAediting_510734	chr6_150398787_+	ENSG00000009765.13	ENST00000229447	hsa-miR-8052	150398785	150398791	7mer-1a	150398773	150398791	148.00	-29.06
CAediting_510734	chr6_150398787_+	ENSG00000009765.13	ENST00000344419	hsa-miR-8052	150398785	150398791	7mer-1a	150398773	150398791	148.00	-29.06
CAediting_510735	chr6_150398809_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4707-5p	150398804	150398810	7mer-m8	150398789	150398811	142.00	-26.95
CAediting_510735	chr6_150398809_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4707-5p	150398804	150398810	7mer-m8	150398789	150398811	142.00	-26.95
CAediting_510736	chr6_150398886_+	ENSG00000009765.13	ENST00000229447	hsa-miR-153-5p	150398879	150398885	7mer-m8	150398864	150398886	148.00	-8.16
CAediting_510736	chr6_150398886_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3680-3p	150398883	150398890	8mer-1a	150398868	150398890	140.00	-14.24
CAediting_510736	chr6_150398886_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3680-3p	150398883	150398890	8mer-1a	150398868	150398890	140.00	-14.24
CAediting_510736	chr6_150398886_+	ENSG00000009765.13	ENST00000344419	hsa-miR-153-5p	150398879	150398885	7mer-m8	150398864	150398886	148.00	-8.16
CAediting_510736	chr6_150398886_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3680-3p	150398883	150398890	8mer-1a	150398868	150398890	140.00	-14.24
CAediting_510736	chr6_150398886_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3680-3p	150398883	150398890	8mer-1a	150398868	150398890	140.00	-14.24
CAediting_510739	chr6_150398942_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6747-3p	150398936	150398943	8mer-1a	150398921	150398943	149.00	-23.42
CAediting_510739	chr6_150398942_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6747-3p	150398936	150398943	8mer-1a	150398921	150398943	149.00	-23.42
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1251-5p	150402972	150402978	7mer-m8	150402959	150402979	141.00	-16.55
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4793-3p	150402977	150402983	7mer-m8	150402962	150402984	161.00	-24.79
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000229447	hsa-miR-5684	150402973	150402979	7mer-m8	150402961	150402980	166.00	-24.20
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000229447	hsa-miR-7703	150402976	150402982	7mer-m8	150402961	150402983	166.00	-27.02
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1251-5p	150402972	150402978	7mer-m8	150402959	150402979	141.00	-16.55
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4793-3p	150402977	150402983	7mer-m8	150402962	150402984	161.00	-24.79
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000344419	hsa-miR-5684	150402973	150402979	7mer-m8	150402961	150402980	166.00	-24.20
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000344419	hsa-miR-7703	150402976	150402982	7mer-m8	150402961	150402983	166.00	-27.02
CAediting_510748	chr6_150402997_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6807-5p	150402995	150403001	7mer-m8	150402981	150403002	140.00	-15.13
CAediting_510748	chr6_150402997_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6807-5p	150402995	150403001	7mer-m8	150402981	150403002	140.00	-15.13
CAediting_510754	chr6_150403053_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1247-3p	150403048	150403054	7mer-m8	150403033	150403055	156.00	-25.69
CAediting_510754	chr6_150403053_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1247-3p	150403048	150403054	7mer-m8	150403033	150403055	156.00	-25.69
CAediting_510755	chr6_150403057_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4691-3p	150403054	150403060	7mer-m8	150403035	150403061	152.00	-27.86
CAediting_510755	chr6_150403057_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6765-3p	150403050	150403056	7mer-m8	150403037	150403057	145.00	-18.72
CAediting_510755	chr6_150403057_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4691-3p	150403054	150403060	7mer-m8	150403035	150403061	152.00	-27.86
CAediting_510755	chr6_150403057_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6765-3p	150403050	150403056	7mer-m8	150403037	150403057	145.00	-18.72

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000229447	hsa-miR-10399-5p	150398781	150398787	7mer-m8	150398767	150398788	144	-10.52
CAediting_510734	chr6_150398787_+	ENSG00000009765.13	ENST00000229447	hsa-miR-10399-5p	150398781	150398787	7mer-m8	150398767	150398788	144	-10.52
CAediting_510737	chr6_150398928_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1200	150398924	150398930	7mer-m8	150398910	150398931	140	-17.96
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1233-5p	150403034	150403040	7mer-m8	150403020	150403041	145	-18.92
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1233-5p	150403034	150403040	7mer-m8	150403020	150403041	145	-18.92
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1262	150402964	150402970	7mer-m8	150402949	150402971	145	-17.25
CAediting_510746	chr6_150402976_+	ENSG00000009765.13	ENST00000229447	hsa-miR-1287-3p	150402971	150402978	8mer-1a	150402957	150402978	148	-17.48
CAediting_510750	chr6_150403007_+	ENSG00000009765.13	ENST00000229447	hsa-miR-17-3p	150403001	150403007	7mer-m8	150402987	150403008	150	-17.33
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000229447	hsa-miR-20a-3p	150402977	150402983	7mer-m8	150402965	150402984	149	-15.86
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000229447	hsa-miR-30b-3p	150403033	150403039	7mer-m8	150403020	150403040	142	-15.74
CAediting_510743	chr6_150400287_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3145-5p	150400282	150400288	7mer-m8	150400268	150400289	152	-10.88
CAediting_510738	chr6_150398941_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3152-5p	150398935	150398941	7mer-m8	150398919	150398942	147	-13.61
CAediting_510739	chr6_150398942_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3152-5p	150398935	150398941	7mer-m8	150398919	150398942	147	-13.61
CAediting_510749	chr6_150403002_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3174	150402998	150403003	6mer	150402982	150403004	146	-17.97
CAediting_510754	chr6_150403053_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3192-5p	150403048	150403053	6mer	150403035	150403054	144	-25.33
CAediting_510752	chr6_150403027_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3614-5p	150403025	150403031	7mer-1a	150403009	150403031	148	-17.4
CAediting_510742	chr6_150399022_+	ENSG00000009765.13	ENST00000229447	hsa-miR-367-5p	150399019	150399026	8mer-1a	150399005	150399026	143	-12.17
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3689a-3p	150403033	150403039	7mer-m8	150403020	150403040	142	-14.67
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3689b-3p	150403033	150403039	7mer-m8	150403021	150403040	148	-17.29
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000229447	hsa-miR-3689c	150403033	150403039	7mer-m8	150403021	150403040	148	-17.29
CAediting_510751	chr6_150403014_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4443	150403007	150403014	8mer-1a	150402994	150403014	146	-21.58
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4701-3p	150402964	150402970	7mer-m8	150402952	150402971	148	-18.39
CAediting_510738	chr6_150398941_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4753-3p	150398940	150398946	7mer-1a	150398925	150398946	148	-27.44
CAediting_510739	chr6_150398942_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4753-3p	150398940	150398946	7mer-1a	150398925	150398946	148	-27.44
CAediting_510743	chr6_150400287_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4764-3p	150400284	150400290	7mer-m8	150400266	150400291	142	-10.67
CAediting_510744	chr6_150400291_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4764-3p	150400284	150400290	7mer-m8	150400266	150400291	142	-10.67
CAediting_510750	chr6_150403007_+	ENSG00000009765.13	ENST00000229447	hsa-miR-485-5p	150403005	150403011	7mer-m8	150402992	150403012	154	-17.86
CAediting_510740	chr6_150398955_+	ENSG00000009765.13	ENST00000229447	hsa-miR-498-5p	150398949	150398955	7mer-m8	150398935	150398956	141	-11.44
CAediting_510741	chr6_150398956_+	ENSG00000009765.13	ENST00000229447	hsa-miR-498-5p	150398949	150398955	7mer-m8	150398935	150398956	141	-11.44
CAediting_510734	chr6_150398787_+	ENSG00000009765.13	ENST00000229447	hsa-miR-5089-5p	150398785	150398791	7mer-m8	150398773	150398792	146	-13.24
CAediting_510755	chr6_150403057_+	ENSG00000009765.13	ENST00000229447	hsa-miR-5690	150403054	150403060	7mer-m8	150403041	150403061	141	-15.77
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6736-5p	150402964	150402970	7mer-m8	150402949	150402971	148	-22.54
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6776-5p	150402965	150402971	7mer-m8	150402953	150402972	152	-22.73
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6778-5p	150403034	150403040	7mer-m8	150403016	150403041	153	-28.66
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6779-5p	150403033	150403039	7mer-m8	150403017	150403040	150	-24.52
CAediting_510754	chr6_150403053_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6852-5p	150403049	150403054	6mer	150403035	150403055	144	-24.72
CAediting_510737	chr6_150398928_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6869-5p	150398921	150398927	7mer-m8	150398906	150398928	146	-14.71
CAediting_510750	chr6_150403007_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6884-5p	150403005	150403011	7mer-m8	150402990	150403012	150	-22.51
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000229447	hsa-miR-7151-3p	150398779	150398786	8mer-1a	150398770	150398786	146	-17.62
CAediting_510742	chr6_150399022_+	ENSG00000009765.13	ENST00000229447	hsa-miR-744-3p	150399018	150399024	7mer-m8	150399004	150399025	140	-14.79
CAediting_510752	chr6_150403027_+	ENSG00000009765.13	ENST00000229447	hsa-miR-8081	150403021	150403027	7mer-m8	150403006	150403028	140	-13.1
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000344419	hsa-miR-10399-5p	150398781	150398787	7mer-m8	150398767	150398788	144	-10.52
CAediting_510734	chr6_150398787_+	ENSG00000009765.13	ENST00000344419	hsa-miR-10399-5p	150398781	150398787	7mer-m8	150398767	150398788	144	-10.52
CAediting_510737	chr6_150398928_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1200	150398924	150398930	7mer-m8	150398910	150398931	140	-17.96
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1233-5p	150403034	150403040	7mer-m8	150403020	150403041	145	-18.92
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1233-5p	150403034	150403040	7mer-m8	150403020	150403041	145	-18.92
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1262	150402964	150402970	7mer-m8	150402949	150402971	145	-17.25
CAediting_510746	chr6_150402976_+	ENSG00000009765.13	ENST00000344419	hsa-miR-1287-3p	150402971	150402978	8mer-1a	150402957	150402978	148	-17.48
CAediting_510750	chr6_150403007_+	ENSG00000009765.13	ENST00000344419	hsa-miR-17-3p	150403001	150403007	7mer-m8	150402987	150403008	150	-17.33
CAediting_510747	chr6_150402979_+	ENSG00000009765.13	ENST00000344419	hsa-miR-20a-3p	150402977	150402983	7mer-m8	150402965	150402984	149	-15.86
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000344419	hsa-miR-30b-3p	150403033	150403039	7mer-m8	150403020	150403040	142	-15.74
CAediting_510743	chr6_150400287_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3145-5p	150400282	150400288	7mer-m8	150400268	150400289	152	-10.88
CAediting_510738	chr6_150398941_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3152-5p	150398935	150398941	7mer-m8	150398919	150398942	147	-13.61
CAediting_510739	chr6_150398942_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3152-5p	150398935	150398941	7mer-m8	150398919	150398942	147	-13.61
CAediting_510749	chr6_150403002_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3174	150402998	150403003	6mer	150402982	150403004	146	-17.97
CAediting_510754	chr6_150403053_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3192-5p	150403048	150403053	6mer	150403035	150403054	144	-25.33
CAediting_510752	chr6_150403027_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3614-5p	150403025	150403031	7mer-1a	150403009	150403031	148	-17.4
CAediting_510742	chr6_150399022_+	ENSG00000009765.13	ENST00000344419	hsa-miR-367-5p	150399019	150399026	8mer-1a	150399005	150399026	143	-12.17
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3689a-3p	150403033	150403039	7mer-m8	150403020	150403040	142	-14.67
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3689b-3p	150403033	150403039	7mer-m8	150403021	150403040	148	-17.29
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000344419	hsa-miR-3689c	150403033	150403039	7mer-m8	150403021	150403040	148	-17.29
CAediting_510751	chr6_150403014_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4443	150403007	150403014	8mer-1a	150402994	150403014	146	-21.58
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4701-3p	150402964	150402970	7mer-m8	150402952	150402971	148	-18.39
CAediting_510738	chr6_150398941_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4753-3p	150398940	150398946	7mer-1a	150398925	150398946	148	-27.44
CAediting_510739	chr6_150398942_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4753-3p	150398940	150398946	7mer-1a	150398925	150398946	148	-27.44
CAediting_510743	chr6_150400287_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4764-3p	150400284	150400290	7mer-m8	150400266	150400291	142	-10.67
CAediting_510744	chr6_150400291_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4764-3p	150400284	150400290	7mer-m8	150400266	150400291	142	-10.67
CAediting_510750	chr6_150403007_+	ENSG00000009765.13	ENST00000344419	hsa-miR-485-5p	150403005	150403011	7mer-m8	150402992	150403012	154	-17.86
CAediting_510740	chr6_150398955_+	ENSG00000009765.13	ENST00000344419	hsa-miR-498-5p	150398949	150398955	7mer-m8	150398935	150398956	141	-11.44
CAediting_510741	chr6_150398956_+	ENSG00000009765.13	ENST00000344419	hsa-miR-498-5p	150398949	150398955	7mer-m8	150398935	150398956	141	-11.44
CAediting_510734	chr6_150398787_+	ENSG00000009765.13	ENST00000344419	hsa-miR-5089-5p	150398785	150398791	7mer-m8	150398773	150398792	146	-13.24
CAediting_510755	chr6_150403057_+	ENSG00000009765.13	ENST00000344419	hsa-miR-5690	150403054	150403060	7mer-m8	150403041	150403061	141	-15.77
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6736-5p	150402964	150402970	7mer-m8	150402949	150402971	148	-22.54
CAediting_510745	chr6_150402967_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6776-5p	150402965	150402971	7mer-m8	150402953	150402972	152	-22.73
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6778-5p	150403034	150403040	7mer-m8	150403016	150403041	153	-28.66
CAediting_510753	chr6_150403040_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6779-5p	150403033	150403039	7mer-m8	150403017	150403040	150	-24.52
CAediting_510754	chr6_150403053_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6852-5p	150403049	150403054	6mer	150403035	150403055	144	-24.72
CAediting_510737	chr6_150398928_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6869-5p	150398921	150398927	7mer-m8	150398906	150398928	146	-14.71
CAediting_510750	chr6_150403007_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6884-5p	150403005	150403011	7mer-m8	150402990	150403012	150	-22.51
CAediting_510733	chr6_150398786_+	ENSG00000009765.13	ENST00000344419	hsa-miR-7151-3p	150398779	150398786	8mer-1a	150398770	150398786	146	-17.62
CAediting_510742	chr6_150399022_+	ENSG00000009765.13	ENST00000344419	hsa-miR-744-3p	150399018	150399024	7mer-m8	150399004	150399025	140	-14.79
CAediting_510752	chr6_150403027_+	ENSG00000009765.13	ENST00000344419	hsa-miR-8081	150403021	150403027	7mer-m8	150403006	150403028	140	-13.1

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000009765.13	ENST00000229447	hsa-miR-605-3p	150399712	150399719	8mer-1a	150399698	150399719	158	-21.69
CAediting_748296	chr10_51299626_+	ENSG00000009765.13	ENST00000229447	hsa-miR-605-3p	150401212	150401218	7mer-m8	150401198	150401219	151	-15.33
CAediting_748296	chr10_51299626_+	ENSG00000009765.13	ENST00000229447	hsa-miR-605-3p	150403271	150403277	7mer-m8	150403256	150403278	160	-24.53
CAediting_1306324	chr19_13836464_-	ENSG00000009765.13	ENST00000229447	hsa-miR-27a-3p	150401768	150401774	7mer-m8	150401752	150401775	153	-24.32
CAediting_393	chr1_1167164_+	ENSG00000009765.13	ENST00000229447	hsa-miR-200b-3p	150403805	150403811	7mer-m8	150403792	150403812	142	-10.46
CAediting_1306324	chr19_13836464_-	ENSG00000009765.13	ENST00000367335	hsa-miR-27a-3p	150395484	150395490	7mer-m8	150395474	150395491	142	-18.1
CAediting_748296	chr10_51299626_+	ENSG00000009765.13	ENST00000344419	hsa-miR-605-3p	150399712	150399719	8mer-1a	150399698	150399719	158	-21.69
CAediting_748296	chr10_51299626_+	ENSG00000009765.13	ENST00000344419	hsa-miR-605-3p	150401212	150401218	7mer-m8	150401198	150401219	151	-15.33
CAediting_748296	chr10_51299626_+	ENSG00000009765.13	ENST00000344419	hsa-miR-605-3p	150403271	150403277	7mer-m8	150403256	150403278	160	-24.53
CAediting_1306324	chr19_13836464_-	ENSG00000009765.13	ENST00000344419	hsa-miR-27a-3p	150401768	150401774	7mer-m8	150401752	150401775	153	-24.32
CAediting_393	chr1_1167164_+	ENSG00000009765.13	ENST00000344419	hsa-miR-200b-3p	150403805	150403811	7mer-m8	150403792	150403812	142	-10.46
CAediting_1306324	chr19_13836464_-	ENSG00000009765.13	ENST00000425615	hsa-miR-27a-3p	150395484	150395490	7mer-m8	150395474	150395491	142	-18.1
CAediting_1054808	chr15_66496985_-	ENSG00000009765.13	ENST00000229447	hsa-miR-4512	150399844	150399850	7mer-m8	150399832	150399851	154	-25.09
CAediting_1229415	chr17_67471547_+	ENSG00000009765.13	ENST00000229447	hsa-miR-548aa	150398516	150398522	7mer-m8	150398499	150398523	147	-9.84
CAediting_1229415	chr17_67471547_+	ENSG00000009765.13	ENST00000229447	hsa-miR-548aa	150398655	150398661	7mer-m8	150398638	150398662	149	-13.03
CAediting_1351755	chr19_40282625_-	ENSG00000009765.13	ENST00000229447	hsa-miR-641	150402459	150402465	7mer-m8	150402441	150402466	148	-20.39
CAediting_77128	chr1_85133844_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4423-3p	150402009	150402016	8mer-1a	150401996	150402016	166	-25.16
CAediting_228905	chr2_188297554_+	ENSG00000009765.13	ENST00000229447	hsa-miR-561-3p	150399514	150399520	7mer-m8	150399501	150399521	144	-10.51
CAediting_228905	chr2_188297554_+	ENSG00000009765.13	ENST00000229447	hsa-miR-561-3p	150399615	150399621	7mer-m8	150399601	150399622	140	-8.18
CAediting_396018	chr5_1062918_-	ENSG00000009765.13	ENST00000229447	hsa-miR-4635	150398194	150398200	7mer-m8	150398181	150398201	166	-26.94
CAediting_604450	chr7_133034877_-	ENSG00000009765.13	ENST00000229447	hsa-miR-3654	150403597	150403604	8mer-1a	150403581	150403604	147	-25.56
CAediting_524911	chr7_5495852_-	ENSG00000009765.13	ENST00000229447	hsa-miR-589-3p	150402957	150402963	7mer-m8	150402941	150402964	145	-11.89
CAediting_524911	chr7_5495852_-	ENSG00000009765.13	ENST00000500320	hsa-miR-589-3p	150395952	150395958	7mer-m8	150395938	150395959	144	-24.37
CAediting_1054808	chr15_66496985_-	ENSG00000009765.13	ENST00000344419	hsa-miR-4512	150399844	150399850	7mer-m8	150399832	150399851	154	-25.09
CAediting_1229415	chr17_67471547_+	ENSG00000009765.13	ENST00000344419	hsa-miR-548aa	150398516	150398522	7mer-m8	150398499	150398523	147	-9.84
CAediting_1229415	chr17_67471547_+	ENSG00000009765.13	ENST00000344419	hsa-miR-548aa	150398655	150398661	7mer-m8	150398638	150398662	149	-13.03
CAediting_1351755	chr19_40282625_-	ENSG00000009765.13	ENST00000344419	hsa-miR-641	150402459	150402465	7mer-m8	150402441	150402466	148	-20.39
CAediting_86358	chr1_109598906_+	ENSG00000009765.13	ENST00000344419	hsa-miR-197-5p	150405360	150405366	7mer-m8	150405345	150405367	162	-29.21
CAediting_77128	chr1_85133844_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4423-3p	150402009	150402016	8mer-1a	150401996	150402016	166	-25.16
CAediting_228905	chr2_188297554_+	ENSG00000009765.13	ENST00000344419	hsa-miR-561-3p	150399514	150399520	7mer-m8	150399501	150399521	144	-10.51
CAediting_228905	chr2_188297554_+	ENSG00000009765.13	ENST00000344419	hsa-miR-561-3p	150399615	150399621	7mer-m8	150399601	150399622	140	-8.18
CAediting_228905	chr2_188297554_+	ENSG00000009765.13	ENST00000344419	hsa-miR-561-3p	150405265	150405271	7mer-m8	150405251	150405272	140	-6.29
CAediting_604450	chr7_133034877_-	ENSG00000009765.13	ENST00000344419	hsa-miR-3654	150403597	150403604	8mer-1a	150403581	150403604	147	-25.56
CAediting_524911	chr7_5495852_-	ENSG00000009765.13	ENST00000344419	hsa-miR-589-3p	150402957	150402963	7mer-m8	150402941	150402964	145	-11.89
CAediting_524911	chr7_5495852_-	ENSG00000009765.13	ENST00000344419	hsa-miR-589-3p	150405961	150405968	8mer-1a	150405940	150405968	148	-21.58
CAediting_396018	chr5_1062918_-	ENSG00000009765.13	ENST00000422583	hsa-miR-4635	150392489	150392496	8mer-1a	150392475	150392496	161	-26.2
CAediting_1229413	chr17_67471544_+	ENSG00000009765.13	ENST00000422583	hsa-miR-548aa	150394164	150394170	7mer-m8	150394147	150394171	150	-12.1
CAediting_468389	chr6_31355314_-	ENSG00000009765.13	ENST00000229447	hsa-miR-6891-5p	150400111	150400117	7mer-m8	150400100	150400118	151	-21.76
CAediting_468389	chr6_31355314_-	ENSG00000009765.13	ENST00000229447	hsa-miR-6891-5p	150402331	150402338	8mer-1a	150402320	150402338	140	-18.61
CAediting_1524209	chrX_134546392_-	ENSG00000009765.13	ENST00000500320	hsa-miR-503-5p	150396198	150396203	6mer	150396181	150396204	143	-24.41
CAediting_468389	chr6_31355314_-	ENSG00000009765.13	ENST00000344419	hsa-miR-6891-5p	150400111	150400117	7mer-m8	150400100	150400118	151	-21.76
CAediting_468389	chr6_31355314_-	ENSG00000009765.13	ENST00000344419	hsa-miR-6891-5p	150402331	150402338	8mer-1a	150402320	150402338	140	-18.61

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1160181	chr17_7017644_-	ENSG00000009765.13	ENST00000229447	hsa-miR-195-3p	150403102	150403108	7mer-m8	150403086	150403109	142	-13.71
CAediting_1160181	chr17_7017644_-	ENSG00000009765.13	ENST00000229447	hsa-miR-195-3p	150404264	150404271	8mer-1a	150404248	150404271	146	-7.31
CAediting_393	chr1_1167164_+	ENSG00000009765.13	ENST00000229447	hsa-miR-200b-3p	150401994	150402000	7mer-m8	150401981	150402001	146	-8.96
CAediting_393	chr1_1167164_+	ENSG00000009765.13	ENST00000229447	hsa-miR-200b-3p	150402775	150402781	7mer-m8	150402760	150402782	143	-11.11
CAediting_688080	chr9_63819626_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4477b	150404310	150404316	7mer-m8	150404293	150404317	154	-12.39
CAediting_414656	chr5_72878640_+	ENSG00000009765.13	ENST00000229447	hsa-miR-4804-3p	150401234	150401240	7mer-m8	150401221	150401241	151	-14.75
CAediting_524911	chr7_5495852_-	ENSG00000009765.13	ENST00000229447	hsa-miR-589-3p	150401723	150401730	8mer-1a	150401707	150401730	143	-13.46
CAediting_1351755	chr19_40282625_-	ENSG00000009765.13	ENST00000229447	hsa-miR-641	150401812	150401818	7mer-1a	150401795	150401818	142	-15.94
CAediting_1351755	chr19_40282625_-	ENSG00000009765.13	ENST00000229447	hsa-miR-641	150403815	150403821	7mer-m8	150403798	150403822	141	-9.96
CAediting_580943	chr7_100356700_+	ENSG00000009765.13	ENST00000229447	hsa-miR-6840-3p	150400678	150400684	7mer-m8	150400661	150400685	151	-26.11
CAediting_468389	chr6_31355314_-	ENSG00000009765.13	ENST00000229447	hsa-miR-6891-5p	150402249	150402255	7mer-m8	150402236	150402256	145	-15.01
CAediting_1160181	chr17_7017644_-	ENSG00000009765.13	ENST00000344419	hsa-miR-195-3p	150403102	150403108	7mer-m8	150403086	150403109	142	-13.71
CAediting_1160181	chr17_7017644_-	ENSG00000009765.13	ENST00000344419	hsa-miR-195-3p	150404264	150404271	8mer-1a	150404248	150404271	146	-7.31
CAediting_1160181	chr17_7017644_-	ENSG00000009765.13	ENST00000344419	hsa-miR-195-3p	150405877	150405884	8mer-1a	150405863	150405884	140	-5.43
CAediting_393	chr1_1167164_+	ENSG00000009765.13	ENST00000344419	hsa-miR-200b-3p	150401994	150402000	7mer-m8	150401981	150402001	146	-8.96
CAediting_393	chr1_1167164_+	ENSG00000009765.13	ENST00000344419	hsa-miR-200b-3p	150402775	150402781	7mer-m8	150402760	150402782	143	-11.11
CAediting_688080	chr9_63819626_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4477b	150404310	150404316	7mer-m8	150404293	150404317	154	-12.39
CAediting_1054808	chr15_66496985_-	ENSG00000009765.13	ENST00000344419	hsa-miR-4512	150405216	150405222	7mer-m8	150405203	150405223	144	-12.61
CAediting_414656	chr5_72878640_+	ENSG00000009765.13	ENST00000344419	hsa-miR-4804-3p	150401234	150401240	7mer-m8	150401221	150401241	151	-14.75
CAediting_524911	chr7_5495852_-	ENSG00000009765.13	ENST00000344419	hsa-miR-589-3p	150401723	150401730	8mer-1a	150401707	150401730	143	-13.46
CAediting_1351755	chr19_40282625_-	ENSG00000009765.13	ENST00000344419	hsa-miR-641	150401812	150401818	7mer-1a	150401795	150401818	142	-15.94
CAediting_1351755	chr19_40282625_-	ENSG00000009765.13	ENST00000344419	hsa-miR-641	150403815	150403821	7mer-m8	150403798	150403822	141	-9.96
CAediting_580943	chr7_100356700_+	ENSG00000009765.13	ENST00000344419	hsa-miR-6840-3p	150400678	150400684	7mer-m8	150400661	150400685	151	-26.11
CAediting_468389	chr6_31355314_-	ENSG00000009765.13	ENST00000344419	hsa-miR-6891-5p	150402249	150402255	7mer-m8	150402236	150402256	145	-15.01

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for IYD

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000229447.8	protein_coding
ENST00000344419.6	protein_coding
ENST00000500320.6	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_510733	ENST00000229447.8	chr6_150398786_+	-2344.40	-2344.40	-2407.00
CAediting_510734	ENST00000229447.8	chr6_150398787_+	-2344.40	-2344.40	-2407.00
CAediting_510735	ENST00000229447.8	chr6_150398809_+	-2348.60	-2344.40	-2407.00
CAediting_510736	ENST00000229447.8	chr6_150398886_+	-2345.70	-2344.40	-2407.00
CAediting_510737	ENST00000229447.8	chr6_150398928_+	-2348.30	-2344.40	-2407.00
CAediting_510738	ENST00000229447.8	chr6_150398941_+	-2346.50	-2344.40	-2407.00
CAediting_510739	ENST00000229447.8	chr6_150398942_+	-2348.70	-2344.40	-2407.00
CAediting_510740	ENST00000229447.8	chr6_150398955_+	-2343.50	-2344.40	-2407.00
CAediting_510741	ENST00000229447.8	chr6_150398956_+	-2350.60	-2344.40	-2407.00
CAediting_510742	ENST00000229447.8	chr6_150399022_+	-2348.60	-2344.40	-2407.00
CAediting_510743	ENST00000229447.8	chr6_150400287_+	-2344.40	-2344.40	-2407.00
CAediting_510744	ENST00000229447.8	chr6_150400291_+	-2348.90	-2344.40	-2407.00
CAediting_510745	ENST00000229447.8	chr6_150402967_+	-2348.00	-2344.40	-2407.00
CAediting_510746	ENST00000229447.8	chr6_150402976_+	-2351.00	-2344.40	-2407.00
CAediting_510747	ENST00000229447.8	chr6_150402979_+	-2350.60	-2344.40	-2407.00
CAediting_510748	ENST00000229447.8	chr6_150402997_+	-2347.60	-2344.40	-2407.00
CAediting_510749	ENST00000229447.8	chr6_150403002_+	-2344.00	-2344.40	-2407.00
CAediting_510750	ENST00000229447.8	chr6_150403007_+	-2343.60	-2344.40	-2407.00
CAediting_510751	ENST00000229447.8	chr6_150403014_+	-2344.40	-2344.40	-2407.00
CAediting_510752	ENST00000229447.8	chr6_150403027_+	-2344.10	-2344.40	-2407.00
CAediting_510753	ENST00000229447.8	chr6_150403040_+	-2348.30	-2344.40	-2407.00
CAediting_510754	ENST00000229447.8	chr6_150403053_+	-2347.30	-2344.40	-2407.00
CAediting_510755	ENST00000229447.8	chr6_150403057_+	-2344.10	-2344.40	-2407.00
CAediting_510733	ENST00000344419.6	chr6_150398786_+	-2676.60	-2676.60	-2737.90
CAediting_510734	ENST00000344419.6	chr6_150398787_+	-2676.60	-2676.60	-2737.90
CAediting_510735	ENST00000344419.6	chr6_150398809_+	-2680.80	-2676.60	-2737.90
CAediting_510736	ENST00000344419.6	chr6_150398886_+	-2676.60	-2676.60	-2737.90
CAediting_510737	ENST00000344419.6	chr6_150398928_+	-2680.50	-2676.60	-2737.90
CAediting_510738	ENST00000344419.6	chr6_150398941_+	-2678.70	-2676.60	-2737.90
CAediting_510739	ENST00000344419.6	chr6_150398942_+	-2680.90	-2676.60	-2737.90
CAediting_510740	ENST00000344419.6	chr6_150398955_+	-2675.70	-2676.60	-2737.90
CAediting_510741	ENST00000344419.6	chr6_150398956_+	-2682.80	-2676.60	-2737.90
CAediting_510742	ENST00000344419.6	chr6_150399022_+	-2680.80	-2676.60	-2737.90
CAediting_510743	ENST00000344419.6	chr6_150400287_+	-2676.60	-2676.60	-2737.90
CAediting_510744	ENST00000344419.6	chr6_150400291_+	-2681.10	-2676.60	-2737.90
CAediting_510745	ENST00000344419.6	chr6_150402967_+	-2680.20	-2676.60	-2737.90
CAediting_510746	ENST00000344419.6	chr6_150402976_+	-2683.20	-2676.60	-2737.90
CAediting_510747	ENST00000344419.6	chr6_150402979_+	-2682.80	-2676.60	-2737.90
CAediting_510748	ENST00000344419.6	chr6_150402997_+	-2679.80	-2676.60	-2737.90
CAediting_510749	ENST00000344419.6	chr6_150403002_+	-2676.20	-2676.60	-2737.90
CAediting_510750	ENST00000344419.6	chr6_150403007_+	-2675.80	-2676.60	-2737.90
CAediting_510751	ENST00000344419.6	chr6_150403014_+	-2676.60	-2676.60	-2737.90
CAediting_510752	ENST00000344419.6	chr6_150403027_+	-2676.30	-2676.60	-2737.90
CAediting_510753	ENST00000344419.6	chr6_150403040_+	-2680.50	-2676.60	-2737.90
CAediting_510754	ENST00000344419.6	chr6_150403053_+	-2679.50	-2676.60	-2737.90
CAediting_510755	ENST00000344419.6	chr6_150403057_+	-2676.30	-2676.60	-2737.90
CAediting_510712	ENST00000500320.6	chr6_150396858_+	-676.60	-675.30	-676.60

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Relation with ADAR for IYD

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
THCA	CAediting_510689	chr6_150392086_+	.	.	.	.	0.0463089684318945	0.218050424937891
THCA	CAediting_510697	chr6_150392158_+	0.00307177849684423	0.372983447357227	.	.	.	.
LIHC	CAediting_510740	chr6_150398955_+	.	.	6.75752713182296e-05	0.399111965333862	.	.
LUAD	CAediting_510740	chr6_150398955_+	.	.	.	.	0.0237296329291608	0.251137145281501
COAD	CAediting_510740	chr6_150398955_+	0.0337604430752065	0.141288926971705	.	.	.	.
THCA	CAediting_510740	chr6_150398955_+	1.2459723695965e-14	0.359959402229525	.	.	.	.
LIHC	CAediting_510741	chr6_150398956_+	.	.	5.70044313953054e-05	0.434286514184489	.	.
LUAD	CAediting_510741	chr6_150398956_+	.	.	0.0232269647403049	0.269147517769771	.	.
COAD	CAediting_510741	chr6_150398956_+	0.0273830138780973	0.167745964893549	.	.	.	.
THCA	CAediting_510741	chr6_150398956_+	3.00350859728847e-24	0.455209792124996	.	.	.	.
THCA	CAediting_510743	chr6_150400287_+	0.00015485862566056	0.267677156152575	.	.	.	.
THCA	CAediting_510744	chr6_150400291_+	1.70080764720354e-16	0.398624734869977	.	.	.	.
LIHC	CAediting_510745	chr6_150402967_+	0.0343768078005692	0.260871982735254	.	.	.	.
THCA	CAediting_510753	chr6_150403040_+	0.00425166760213128	0.194244466893819	.	.	.	.

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Relation with cancer stages for IYD

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
STAD	pathologic_stage	CAediting_510745	chr6_150402967_+	0.00258304394467668	-0.338739781844085
THCA	pathologic_stage	CAediting_510744	chr6_150400291_+	0.0446268308204309	0.101749434003227
THCA	pathologic_stage	CAediting_510745	chr6_150402967_+	4.18487376240686e-06	0.219595975543639
THCA	pathologic_stage	CAediting_510753	chr6_150403040_+	0.000743322820329542	0.229912175914322

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Relation with survival for IYD

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for IYD

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for IYD

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
IYD	C0342195	Thyroid Dyshormonogenesis 4	2	CTD_human;GENOMICS_ENGLAND;UNIPROT
IYD	C1848805	Thyroid Dyshormonogenesis 1	2	ORPHANET
IYD	C0010308	Congenital Hypothyroidism	1	GENOMICS_ENGLAND
IYD	C0018021	Goiter	1	GENOMICS_ENGLAND
IYD	C0023893	Liver Cirrhosis, Experimental	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene