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Editing gene: GPR153 (CAeditome ID:387509)

Gene summary for GPR153

Gene summary

Gene information	Gene symbol	GPR153
	Gene ID	387509
	Gene name	G protein-coupled receptor 153
	Synonyms	PGR1
	Cytomap	1p36.31
	Type of gene	protein-coding
	Description	probable G-protein coupled receptor 153G-protein coupled receptor PGR1
	Modification date	20210518
	UniProtAcc	Q6NV75
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for GPR153

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000158292.6

RNA A-to-I editing events in Cancer.

CAediting_4987(6251857, -), CAediting_4988(6251864, -), CAediting_4989(6251885, -), CAediting_4990(6251894, -), CAediting_4991(6251907, -), CAediting_4992(6251911, -), CAediting_4993(6251928, -), CAediting_4994(6251933, -), CAediting_4995(6251934, -), CAediting_4996(6251940, -), CAediting_4997(6253132, -), CAediting_4998(6253133, -), CAediting_4999(6253135, -), CAediting_5000(6253141, -), CAediting_5001(6253147, -), CAediting_5002(6253157, -), CAediting_5003(6253175, -), CAediting_5004(6253204, -), CAediting_5005(6253220, -), CAediting_5006(6253273, -), CAediting_5007(6253275, -), CAediting_5008(6253313, -), CAediting_5009(6253314, -), CAediting_5010(6253333, -), CAediting_5011(6253344, -), CAediting_5012(6253349, -), CAediting_5013(6253350, -), CAediting_5014(6253352, -), CAediting_5015(6253358, -), CAediting_5016(6255363, -), CAediting_5017(6255412, -), CAediting_5018(6255426, -), CAediting_5019(6255470, -), CAediting_5020(6255567, -), CAediting_5021(6255572, -), CAediting_5022(6255596, -), CAediting_5023(6255621, -), CAediting_5024(6255631, -), CAediting_5025(6255683, -), CAediting_5026(6255715, -), CAediting_5027(6255718, -), CAediting_5028(6255720, -), CAediting_5029(6255721, -), CAediting_5030(6255725, -), CAediting_5031(6255749, -), CAediting_5032(6255750, -), CAediting_5033(6255777, -), CAediting_5034(6255781, -), CAediting_5035(6255790, -), CAediting_5036(6255817, -), CAediting_5037(6255867, -), CAediting_5038(6255872, -), CAediting_5039(6255873, -), CAediting_5040(6255925, -), CAediting_5041(6255927, -), CAediting_5042(6255931, -), CAediting_5043(6255960, -), CAediting_5044(6256022, -), CAediting_5045(6256061, -), CAediting_5046(6256067, -), CAediting_5047(6256068, -), CAediting_5048(6256514, -), CAediting_5049(6256532, -), CAediting_5050(6256597, -), CAediting_5051(6256619, -), CAediting_5052(6256729, -), CAediting_5053(6256789, -), CAediting_5054(6258171, -), CAediting_5055(6258224, -), CAediting_5056(6258265, -), CAediting_5057(6258266, -), CAediting_5058(6258292, -), CAediting_5059(6258356, -), CAediting_5060(6258396, -), CAediting_5061(6258401, -), CAediting_5062(6258402, -), CAediting_5063(6258410, -), CAediting_5064(6259010, -), CAediting_5065(6259043, -), CAediting_5066(6259044, -), CAediting_5067(6259069, -), CAediting_5068(6259149, -), CAediting_5069(6259152, -), CAediting_5070(6259153, -), CAediting_5071(6259161, -), CAediting_5072(6259179, -), CAediting_5073(6259185, -), CAediting_5074(6259205, -), CAediting_5075(6259216, -), CAediting_5076(6259218, -), CAediting_5077(6259231, -), CAediting_5078(6259248, -), CAediting_5079(6259260, -), CAediting_5080(6259261, -),

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RNA editing positional annotations for GPR153 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_4987	chr1_6251857_-	intronic
CAediting_4988	chr1_6251864_-	intronic
CAediting_4989	chr1_6251885_-	intronic
CAediting_4990	chr1_6251894_-	intronic
CAediting_4991	chr1_6251907_-	intronic
CAediting_4992	chr1_6251911_-	intronic
CAediting_4993	chr1_6251928_-	intronic
CAediting_4994	chr1_6251933_-	intronic
CAediting_4995	chr1_6251934_-	intronic
CAediting_4996	chr1_6251940_-	intronic
CAediting_4997	chr1_6253132_-	intronic
CAediting_4998	chr1_6253133_-	intronic
CAediting_4999	chr1_6253135_-	intronic
CAediting_5000	chr1_6253141_-	intronic
CAediting_5001	chr1_6253147_-	intronic
CAediting_5002	chr1_6253157_-	intronic
CAediting_5003	chr1_6253175_-	intronic
CAediting_5004	chr1_6253204_-	intronic
CAediting_5005	chr1_6253220_-	intronic
CAediting_5006	chr1_6253273_-	intronic
CAediting_5007	chr1_6253275_-	intronic
CAediting_5008	chr1_6253313_-	intronic
CAediting_5009	chr1_6253314_-	intronic
CAediting_5010	chr1_6253333_-	intronic
CAediting_5011	chr1_6253344_-	intronic
CAediting_5012	chr1_6253349_-	intronic
CAediting_5013	chr1_6253350_-	intronic
CAediting_5014	chr1_6253352_-	intronic
CAediting_5015	chr1_6253358_-	intronic
CAediting_5016	chr1_6255363_-	intronic
CAediting_5017	chr1_6255412_-	intronic
CAediting_5018	chr1_6255426_-	intronic
CAediting_5019	chr1_6255470_-	intronic
CAediting_5020	chr1_6255567_-	intronic
CAediting_5021	chr1_6255572_-	intronic
CAediting_5022	chr1_6255596_-	intronic
CAediting_5023	chr1_6255621_-	intronic
CAediting_5024	chr1_6255631_-	intronic
CAediting_5025	chr1_6255683_-	intronic
CAediting_5026	chr1_6255715_-	intronic
CAediting_5027	chr1_6255718_-	intronic
CAediting_5028	chr1_6255720_-	intronic
CAediting_5029	chr1_6255721_-	intronic
CAediting_5030	chr1_6255725_-	intronic
CAediting_5031	chr1_6255749_-	intronic
CAediting_5032	chr1_6255750_-	intronic
CAediting_5033	chr1_6255777_-	intronic
CAediting_5034	chr1_6255781_-	intronic
CAediting_5035	chr1_6255790_-	intronic
CAediting_5036	chr1_6255817_-	intronic
CAediting_5037	chr1_6255867_-	intronic
CAediting_5038	chr1_6255872_-	intronic
CAediting_5039	chr1_6255873_-	intronic
CAediting_5040	chr1_6255925_-	intronic
CAediting_5041	chr1_6255927_-	intronic
CAediting_5042	chr1_6255931_-	intronic
CAediting_5043	chr1_6255960_-	intronic
CAediting_5044	chr1_6256022_-	intronic
CAediting_5045	chr1_6256061_-	intronic
CAediting_5046	chr1_6256067_-	intronic
CAediting_5047	chr1_6256068_-	intronic
CAediting_5048	chr1_6256514_-	intronic
CAediting_5049	chr1_6256532_-	intronic
CAediting_5050	chr1_6256597_-	intronic
CAediting_5051	chr1_6256619_-	intronic
CAediting_5052	chr1_6256729_-	intronic
CAediting_5053	chr1_6256789_-	intronic
CAediting_5054	chr1_6258171_-	intronic
CAediting_5055	chr1_6258224_-	intronic
CAediting_5056	chr1_6258265_-	intronic
CAediting_5057	chr1_6258266_-	intronic
CAediting_5058	chr1_6258292_-	intronic
CAediting_5059	chr1_6258356_-	intronic
CAediting_5060	chr1_6258396_-	intronic
CAediting_5061	chr1_6258401_-	intronic
CAediting_5062	chr1_6258402_-	intronic
CAediting_5063	chr1_6258410_-	intronic
CAediting_5064	chr1_6259010_-	intronic
CAediting_5065	chr1_6259043_-	intronic
CAediting_5066	chr1_6259044_-	intronic
CAediting_5067	chr1_6259069_-	intronic
CAediting_5068	chr1_6259149_-	intronic
CAediting_5069	chr1_6259152_-	intronic
CAediting_5070	chr1_6259153_-	intronic
CAediting_5071	chr1_6259161_-	intronic
CAediting_5072	chr1_6259179_-	intronic
CAediting_5073	chr1_6259185_-	intronic
CAediting_5074	chr1_6259205_-	intronic
CAediting_5075	chr1_6259216_-	intronic
CAediting_5076	chr1_6259218_-	intronic
CAediting_5077	chr1_6259231_-	intronic
CAediting_5078	chr1_6259248_-	intronic
CAediting_5079	chr1_6259260_-	intronic
CAediting_5080	chr1_6259261_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_4987	chr1_6251857_-	SINE	Alu	AluJb
CAediting_4988	chr1_6251864_-	SINE	Alu	AluJb
CAediting_4989	chr1_6251885_-	SINE	Alu	AluJb
CAediting_4990	chr1_6251894_-	SINE	Alu	AluJb
CAediting_4991	chr1_6251907_-	SINE	Alu	AluJb
CAediting_4992	chr1_6251911_-	SINE	Alu	AluJb
CAediting_4993	chr1_6251928_-	SINE	Alu	AluJb
CAediting_4994	chr1_6251933_-	SINE	Alu	AluJb
CAediting_4995	chr1_6251934_-	SINE	Alu	AluJb
CAediting_4996	chr1_6251940_-	SINE	Alu	AluJb
CAediting_4997	chr1_6253132_-	SINE	Alu	AluSq2
CAediting_4998	chr1_6253133_-	SINE	Alu	AluSq2
CAediting_4999	chr1_6253135_-	SINE	Alu	AluSq2
CAediting_5000	chr1_6253141_-	SINE	Alu	AluSq2
CAediting_5001	chr1_6253147_-	SINE	Alu	AluSq2
CAediting_5002	chr1_6253157_-	SINE	Alu	AluSq2
CAediting_5003	chr1_6253175_-	SINE	Alu	AluSq2
CAediting_5004	chr1_6253204_-	SINE	Alu	AluSq2
CAediting_5005	chr1_6253220_-	SINE	Alu	AluSq2
CAediting_5006	chr1_6253273_-	SINE	Alu	AluSq2
CAediting_5007	chr1_6253275_-	SINE	Alu	AluSq2
CAediting_5008	chr1_6253313_-	SINE	Alu	AluSq2
CAediting_5009	chr1_6253314_-	SINE	Alu	AluSq2
CAediting_5010	chr1_6253333_-	SINE	Alu	AluSq2
CAediting_5011	chr1_6253344_-	SINE	Alu	AluSq2
CAediting_5012	chr1_6253349_-	SINE	Alu	AluSq2
CAediting_5013	chr1_6253350_-	SINE	Alu	AluSq2
CAediting_5014	chr1_6253352_-	SINE	Alu	AluSq2
CAediting_5015	chr1_6253358_-	SINE	Alu	AluSq2
CAediting_5016	chr1_6255363_-	SINE	Alu	AluY
CAediting_5017	chr1_6255412_-	SINE	Alu	AluY
CAediting_5018	chr1_6255426_-	SINE	Alu	AluY
CAediting_5019	chr1_6255470_-	SINE	Alu	AluY
CAediting_5020	chr1_6255567_-	SINE	Alu	AluJr
CAediting_5021	chr1_6255572_-	SINE	Alu	AluJr
CAediting_5022	chr1_6255596_-	SINE	Alu	AluJr
CAediting_5023	chr1_6255621_-	SINE	Alu	AluJr
CAediting_5024	chr1_6255631_-	SINE	Alu	AluJr
CAediting_5025	chr1_6255683_-	SINE	Alu	AluSx3
CAediting_5026	chr1_6255715_-	SINE	Alu	AluSx3
CAediting_5027	chr1_6255718_-	SINE	Alu	AluSx3
CAediting_5028	chr1_6255720_-	SINE	Alu	AluSx3
CAediting_5029	chr1_6255721_-	SINE	Alu	AluSx3
CAediting_5030	chr1_6255725_-	SINE	Alu	AluSx3
CAediting_5031	chr1_6255749_-	SINE	Alu	AluSx3
CAediting_5032	chr1_6255750_-	SINE	Alu	AluSx3
CAediting_5033	chr1_6255777_-	SINE	Alu	AluSx3
CAediting_5034	chr1_6255781_-	SINE	Alu	AluSx3
CAediting_5035	chr1_6255790_-	SINE	Alu	AluSx3
CAediting_5036	chr1_6255817_-	SINE	Alu	AluSx3
CAediting_5037	chr1_6255867_-	SINE	Alu	AluSx3
CAediting_5038	chr1_6255872_-	SINE	Alu	AluSx3
CAediting_5039	chr1_6255873_-	SINE	Alu	AluSx3
CAediting_5040	chr1_6255925_-	SINE	Alu	AluSx3
CAediting_5041	chr1_6255927_-	SINE	Alu	AluSx3
CAediting_5042	chr1_6255931_-	SINE	Alu	AluSx3
CAediting_5043	chr1_6255960_-	SINE	Alu	AluJr
CAediting_5044	chr1_6256022_-	SINE	Alu	AluJr
CAediting_5045	chr1_6256061_-	SINE	Alu	AluJr
CAediting_5046	chr1_6256067_-	SINE	Alu	AluJr
CAediting_5047	chr1_6256068_-	SINE	Alu	AluJr
CAediting_5048	chr1_6256514_-	SINE	Alu	AluSz6
CAediting_5049	chr1_6256532_-	SINE	Alu	AluSz6
CAediting_5050	chr1_6256597_-	SINE	Alu	AluSz6
CAediting_5051	chr1_6256619_-	SINE	Alu	AluSz6
CAediting_5052	chr1_6256729_-	SINE	Alu	FLAM_A
CAediting_5053	chr1_6256789_-	SINE	Alu	FLAM_A
CAediting_5054	chr1_6258171_-	SINE	Alu	AluSq
CAediting_5055	chr1_6258224_-	SINE	Alu	AluSq
CAediting_5056	chr1_6258265_-	SINE	Alu	AluSq
CAediting_5057	chr1_6258266_-	SINE	Alu	AluSq
CAediting_5058	chr1_6258292_-	SINE	Alu	AluSq
CAediting_5059	chr1_6258356_-	SINE	Alu	AluSq
CAediting_5060	chr1_6258396_-	SINE	Alu	AluSq
CAediting_5061	chr1_6258401_-	SINE	Alu	AluSq
CAediting_5062	chr1_6258402_-	SINE	Alu	AluSq
CAediting_5063	chr1_6258410_-	SINE	Alu	AluSq
CAediting_5064	chr1_6259010_-	SINE	Alu	AluJb
CAediting_5065	chr1_6259043_-	SINE	Alu	AluJb
CAediting_5066	chr1_6259044_-	SINE	Alu	AluJb
CAediting_5067	chr1_6259069_-	SINE	Alu	AluJb
CAediting_5068	chr1_6259149_-	SINE	Alu	AluJb
CAediting_5069	chr1_6259152_-	SINE	Alu	AluJb
CAediting_5070	chr1_6259153_-	SINE	Alu	AluJb
CAediting_5071	chr1_6259161_-	SINE	Alu	AluJb
CAediting_5072	chr1_6259179_-	SINE	Alu	AluJb
CAediting_5073	chr1_6259185_-	SINE	Alu	AluJb
CAediting_5074	chr1_6259205_-	SINE	Alu	AluJb
CAediting_5075	chr1_6259216_-	SINE	Alu	AluJb
CAediting_5076	chr1_6259218_-	SINE	Alu	AluJb
CAediting_5077	chr1_6259231_-	SINE	Alu	AluJb
CAediting_5078	chr1_6259248_-	SINE	Alu	AluJb
CAediting_5079	chr1_6259260_-	SINE	Alu	AluJb
CAediting_5080	chr1_6259261_-	SINE	Alu	AluJb

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RNA A-to-I editing events in the alternative splicing sites for GPR153

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000158292.6.GPR153.

Correlation between RNA A-to-I editing and PSI for ENSG00000158292.6.GPR153.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GPR153

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for GPR153

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for GPR153

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GPR153

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for GPR153

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
STAD	CAediting_4990	chr1_6251894_-	.	.	0.00547925649623992	0.372944200755837	.	.
SKCM	CAediting_4990	chr1_6251894_-	0.0272960130426003	0.156488951493783	.	.	.	.
SKCM	CAediting_4994	chr1_6251933_-	0.00548398025126074	0.229527993389388	.	.	.	.

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Relation with cancer stages for GPR153

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
STAD	pathologic_stage	CAediting_4990	chr1_6251894_-	0.00184458185780366	0.421768097123699

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Relation with survival for GPR153

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for GPR153

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for GPR153

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
GPR153	C0036341	Schizophrenia	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene