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Editing gene: KCNJ15 (CAeditome ID:3772)

Gene summary for KCNJ15

Gene summary

Gene information	Gene symbol	KCNJ15
	Gene ID	3772
	Gene name	potassium inwardly rectifying channel subfamily J member 15
	Synonyms	IRKK\|KIR1.3\|KIR4.2
	Cytomap	21q22.13-q22.2
	Type of gene	protein-coding
	Description	ATP-sensitive inward rectifier potassium channel 15inward rectifier K(+) channel Kir1.3inward rectifier K(+) channel Kir4.2inward rectifier K+ channel KIR4.2potassium channel, inwardly rectifying subfamily J member 15potassium voltage-gated channel s
	Modification date	20210518
	UniProtAcc	Q99712
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for KCNJ15

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000157551.16

RNA A-to-I editing events in Cancer.

CAediting_1452354(38175084, +), CAediting_1452355(38232278, +), CAediting_1452356(38232286, +), CAediting_1452357(38232289, +), CAediting_1452358(38233632, +), CAediting_1452359(38233633, +), CAediting_1452360(38233638, +), CAediting_1452361(38233639, +), CAediting_1452362(38233640, +), CAediting_1452363(38233647, +), CAediting_1452364(38233655, +), CAediting_1452365(38233658, +), CAediting_1452366(38233661, +), CAediting_1452367(38233663, +), CAediting_1452368(38233667, +), CAediting_1452369(38233674, +), CAediting_1452370(38233675, +), CAediting_1452371(38233676, +), CAediting_1452372(38233683, +), CAediting_1452373(38233691, +), CAediting_1452374(38241734, +), CAediting_1452375(38241757, +), CAediting_1452376(38241781, +), CAediting_1452377(38241842, +), CAediting_1452378(38241848, +), CAediting_1452379(38241849, +), CAediting_1452380(38241875, +), CAediting_1452381(38241893, +), CAediting_1452382(38241904, +), CAediting_1452383(38241918, +), CAediting_1452384(38243449, +), CAediting_1452385(38243522, +), CAediting_1452386(38243547, +), CAediting_1452387(38243561, +), CAediting_1452388(38259991, +), CAediting_1452389(38286163, +), CAediting_1452390(38287526, +), CAediting_1452391(38287529, +), CAediting_1452392(38287530, +), CAediting_1452393(38287589, +), CAediting_1452394(38288944, +), CAediting_1452395(38288945, +), CAediting_1452396(38289010, +), CAediting_1452397(38289011, +), CAediting_1452398(38289026, +), CAediting_1452399(38289035, +), CAediting_1452400(38289037, +), CAediting_1452401(38289050, +), CAediting_1452402(38289074, +), CAediting_1452403(38289076, +), CAediting_1452404(38289077, +), CAediting_1452405(38289082, +), CAediting_1452406(38289122, +), CAediting_1452407(38289131, +), CAediting_1452408(38289142, +), CAediting_1452409(38289154, +), CAediting_1452410(38289186, +), CAediting_1452411(38289478, +), CAediting_1452412(38289634, +), CAediting_1452413(38302892, +), CAediting_1452414(38302900, +), CAediting_1452415(38302911, +), CAediting_1452416(38302922, +), CAediting_1452417(38302926, +), CAediting_1452418(38302927, +), CAediting_1452419(38302929, +), CAediting_1452420(38302948, +), CAediting_1452421(38302949, +), CAediting_1452422(38302951, +), CAediting_1452423(38302962, +), CAediting_1452424(38302968, +), CAediting_1452425(38302972, +), CAediting_1452426(38302974, +), CAediting_1452427(38302975, +), CAediting_1452428(38302984, +), CAediting_1452429(38302985, +), CAediting_1452430(38302996, +), CAediting_1452431(38303665, +), CAediting_1452432(38303671, +), CAediting_1452433(38303672, +), CAediting_1452434(38303675, +), CAediting_1452435(38303676, +), CAediting_1452436(38303679, +), CAediting_1452437(38303680, +), CAediting_1452438(38303681, +), CAediting_1452439(38303682, +), CAediting_1452440(38303684, +), CAediting_1452441(38303685, +), CAediting_1452442(38303688, +), CAediting_1452443(38303704, +), CAediting_1452444(38303714, +), CAediting_1452445(38303723, +), CAediting_1452446(38303730, +), CAediting_1452447(38303732, +), CAediting_1452448(38303748, +), CAediting_1452449(38303751, +), CAediting_1452450(38303755, +), CAediting_1452451(38303757, +), CAediting_1452452(38303767, +), CAediting_1452453(38304727, +), CAediting_1452454(38304753, +), CAediting_1452455(38304805, +), CAediting_1452456(38304817, +), CAediting_1452457(38304937, +), CAediting_1452458(38304959, +), CAediting_1452459(38304965, +), CAediting_1452460(38304969, +), CAediting_1452461(38304976, +), CAediting_1452462(38304986, +), CAediting_1452463(38305001, +), CAediting_1452464(38305021, +), CAediting_1452465(38305025, +), CAediting_1452466(38305029, +), CAediting_1452467(38305030, +), CAediting_1452468(38305050, +), CAediting_1452469(38305059, +), CAediting_1452470(38305068, +), CAediting_1452471(38305069, +), CAediting_1452472(38305071, +), CAediting_1452473(38305088, +), CAediting_1452474(38305097, +),

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RNA editing positional annotations for KCNJ15 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1452354	chr21_38175084_+	ncRNA_intronic
CAediting_1452355	chr21_38232278_+	intronic
CAediting_1452356	chr21_38232286_+	intronic
CAediting_1452357	chr21_38232289_+	intronic
CAediting_1452358	chr21_38233632_+	intronic
CAediting_1452359	chr21_38233633_+	intronic
CAediting_1452360	chr21_38233638_+	intronic
CAediting_1452361	chr21_38233639_+	intronic
CAediting_1452362	chr21_38233640_+	intronic
CAediting_1452363	chr21_38233647_+	intronic
CAediting_1452364	chr21_38233655_+	intronic
CAediting_1452365	chr21_38233658_+	intronic
CAediting_1452366	chr21_38233661_+	intronic
CAediting_1452367	chr21_38233663_+	intronic
CAediting_1452368	chr21_38233667_+	intronic
CAediting_1452369	chr21_38233674_+	intronic
CAediting_1452370	chr21_38233675_+	intronic
CAediting_1452371	chr21_38233676_+	intronic
CAediting_1452372	chr21_38233683_+	intronic
CAediting_1452373	chr21_38233691_+	intronic
CAediting_1452374	chr21_38241734_+	intronic
CAediting_1452375	chr21_38241757_+	intronic
CAediting_1452376	chr21_38241781_+	intronic
CAediting_1452377	chr21_38241842_+	intronic
CAediting_1452378	chr21_38241848_+	intronic
CAediting_1452379	chr21_38241849_+	intronic
CAediting_1452380	chr21_38241875_+	intronic
CAediting_1452381	chr21_38241893_+	intronic
CAediting_1452382	chr21_38241904_+	intronic
CAediting_1452383	chr21_38241918_+	intronic
CAediting_1452384	chr21_38243449_+	intronic
CAediting_1452385	chr21_38243522_+	intronic
CAediting_1452386	chr21_38243547_+	intronic
CAediting_1452387	chr21_38243561_+	intronic
CAediting_1452388	chr21_38259991_+	intronic
CAediting_1452389	chr21_38286163_+	intronic
CAediting_1452390	chr21_38287526_+	intronic
CAediting_1452391	chr21_38287529_+	intronic
CAediting_1452392	chr21_38287530_+	intronic
CAediting_1452393	chr21_38287589_+	intronic
CAediting_1452394	chr21_38288944_+	intronic
CAediting_1452395	chr21_38288945_+	intronic
CAediting_1452396	chr21_38289010_+	intronic
CAediting_1452397	chr21_38289011_+	intronic
CAediting_1452398	chr21_38289026_+	intronic
CAediting_1452399	chr21_38289035_+	intronic
CAediting_1452400	chr21_38289037_+	intronic
CAediting_1452401	chr21_38289050_+	intronic
CAediting_1452402	chr21_38289074_+	intronic
CAediting_1452403	chr21_38289076_+	intronic
CAediting_1452404	chr21_38289077_+	intronic
CAediting_1452405	chr21_38289082_+	intronic
CAediting_1452406	chr21_38289122_+	intronic
CAediting_1452407	chr21_38289131_+	intronic
CAediting_1452408	chr21_38289142_+	intronic
CAediting_1452409	chr21_38289154_+	intronic
CAediting_1452410	chr21_38289186_+	intronic
CAediting_1452411	chr21_38289478_+	intronic
CAediting_1452412	chr21_38289634_+	intronic
CAediting_1452413	chr21_38302892_+	UTR3
CAediting_1452414	chr21_38302900_+	UTR3
CAediting_1452415	chr21_38302911_+	UTR3
CAediting_1452416	chr21_38302922_+	UTR3
CAediting_1452417	chr21_38302926_+	UTR3
CAediting_1452418	chr21_38302927_+	UTR3
CAediting_1452419	chr21_38302929_+	UTR3
CAediting_1452420	chr21_38302948_+	UTR3
CAediting_1452421	chr21_38302949_+	UTR3
CAediting_1452422	chr21_38302951_+	UTR3
CAediting_1452423	chr21_38302962_+	UTR3
CAediting_1452424	chr21_38302968_+	UTR3
CAediting_1452425	chr21_38302972_+	UTR3
CAediting_1452426	chr21_38302974_+	UTR3
CAediting_1452427	chr21_38302975_+	UTR3
CAediting_1452428	chr21_38302984_+	UTR3
CAediting_1452429	chr21_38302985_+	UTR3
CAediting_1452430	chr21_38302996_+	UTR3
CAediting_1452431	chr21_38303665_+	UTR3
CAediting_1452432	chr21_38303671_+	UTR3
CAediting_1452433	chr21_38303672_+	UTR3
CAediting_1452434	chr21_38303675_+	UTR3
CAediting_1452435	chr21_38303676_+	UTR3
CAediting_1452436	chr21_38303679_+	UTR3
CAediting_1452437	chr21_38303680_+	UTR3
CAediting_1452438	chr21_38303681_+	UTR3
CAediting_1452439	chr21_38303682_+	UTR3
CAediting_1452440	chr21_38303684_+	UTR3
CAediting_1452441	chr21_38303685_+	UTR3
CAediting_1452442	chr21_38303688_+	UTR3
CAediting_1452443	chr21_38303704_+	UTR3
CAediting_1452444	chr21_38303714_+	UTR3
CAediting_1452445	chr21_38303723_+	UTR3
CAediting_1452446	chr21_38303730_+	UTR3
CAediting_1452447	chr21_38303732_+	UTR3
CAediting_1452448	chr21_38303748_+	UTR3
CAediting_1452449	chr21_38303751_+	UTR3
CAediting_1452450	chr21_38303755_+	UTR3
CAediting_1452451	chr21_38303757_+	UTR3
CAediting_1452452	chr21_38303767_+	UTR3
CAediting_1452453	chr21_38304727_+	UTR3
CAediting_1452454	chr21_38304753_+	UTR3
CAediting_1452455	chr21_38304805_+	UTR3
CAediting_1452456	chr21_38304817_+	UTR3
CAediting_1452457	chr21_38304937_+	UTR3
CAediting_1452458	chr21_38304959_+	UTR3
CAediting_1452459	chr21_38304965_+	UTR3
CAediting_1452460	chr21_38304969_+	UTR3
CAediting_1452461	chr21_38304976_+	UTR3
CAediting_1452462	chr21_38304986_+	UTR3
CAediting_1452463	chr21_38305001_+	UTR3
CAediting_1452464	chr21_38305021_+	UTR3
CAediting_1452465	chr21_38305025_+	UTR3
CAediting_1452466	chr21_38305029_+	UTR3
CAediting_1452467	chr21_38305030_+	UTR3
CAediting_1452468	chr21_38305050_+	UTR3
CAediting_1452469	chr21_38305059_+	UTR3
CAediting_1452470	chr21_38305068_+	UTR3
CAediting_1452471	chr21_38305069_+	UTR3
CAediting_1452472	chr21_38305071_+	UTR3
CAediting_1452473	chr21_38305088_+	UTR3
CAediting_1452474	chr21_38305097_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1452354	chr21_38175084_+	LTR	ERVL	MER74A
CAediting_1452355	chr21_38232278_+	LINE	L1	L1MB8
CAediting_1452356	chr21_38232286_+	LINE	L1	L1MB8
CAediting_1452357	chr21_38232289_+	LINE	L1	L1MB8
CAediting_1452358	chr21_38233632_+	LINE	L1	L1MB8
CAediting_1452359	chr21_38233633_+	LINE	L1	L1MB8
CAediting_1452360	chr21_38233638_+	LINE	L1	L1MB8
CAediting_1452361	chr21_38233639_+	LINE	L1	L1MB8
CAediting_1452362	chr21_38233640_+	LINE	L1	L1MB8
CAediting_1452363	chr21_38233647_+	LINE	L1	L1MB8
CAediting_1452364	chr21_38233655_+	LINE	L1	L1MB8
CAediting_1452365	chr21_38233658_+	LINE	L1	L1MB8
CAediting_1452366	chr21_38233661_+	LINE	L1	L1MB8
CAediting_1452367	chr21_38233663_+	LINE	L1	L1MB8
CAediting_1452368	chr21_38233667_+	LINE	L1	L1MB8
CAediting_1452369	chr21_38233674_+	LINE	L1	L1MB8
CAediting_1452370	chr21_38233675_+	LINE	L1	L1MB8
CAediting_1452371	chr21_38233676_+	LINE	L1	L1MB8
CAediting_1452372	chr21_38233683_+	LINE	L1	L1MB8
CAediting_1452373	chr21_38233691_+	LINE	L1	L1MB8
CAediting_1452374	chr21_38241734_+	SINE	Alu	AluSx1
CAediting_1452375	chr21_38241757_+	SINE	Alu	AluSx1
CAediting_1452376	chr21_38241781_+	SINE	Alu	AluSx1
CAediting_1452377	chr21_38241842_+	SINE	Alu	AluSx1
CAediting_1452378	chr21_38241848_+	SINE	Alu	AluSx1
CAediting_1452379	chr21_38241849_+	SINE	Alu	AluSx1
CAediting_1452380	chr21_38241875_+	SINE	Alu	AluSx1
CAediting_1452381	chr21_38241893_+	SINE	Alu	AluSx1
CAediting_1452382	chr21_38241904_+	SINE	Alu	AluSx1
CAediting_1452383	chr21_38241918_+	SINE	Alu	AluSx1
CAediting_1452384	chr21_38243449_+	SINE	Alu	AluSx1
CAediting_1452385	chr21_38243522_+	SINE	Alu	AluSx1
CAediting_1452386	chr21_38243547_+	SINE	Alu	AluSx1
CAediting_1452387	chr21_38243561_+	SINE	Alu	AluSx1
CAediting_1452389	chr21_38286163_+	SINE	Alu	AluY
CAediting_1452390	chr21_38287526_+	DNA	hAT-Blackjack	MER53
CAediting_1452391	chr21_38287529_+	DNA	hAT-Blackjack	MER53
CAediting_1452392	chr21_38287530_+	DNA	hAT-Blackjack	MER53
CAediting_1452393	chr21_38287589_+	DNA	hAT-Blackjack	MER53
CAediting_1452394	chr21_38288944_+	SINE	Alu	AluSz
CAediting_1452395	chr21_38288945_+	SINE	Alu	AluSz
CAediting_1452396	chr21_38289010_+	SINE	Alu	AluSz
CAediting_1452397	chr21_38289011_+	SINE	Alu	AluSz
CAediting_1452398	chr21_38289026_+	SINE	Alu	AluSz
CAediting_1452399	chr21_38289035_+	SINE	Alu	AluSz
CAediting_1452400	chr21_38289037_+	SINE	Alu	AluSz
CAediting_1452401	chr21_38289050_+	SINE	Alu	AluSz
CAediting_1452402	chr21_38289074_+	SINE	Alu	AluSz
CAediting_1452403	chr21_38289076_+	SINE	Alu	AluSz
CAediting_1452404	chr21_38289077_+	SINE	Alu	AluSz
CAediting_1452405	chr21_38289082_+	SINE	Alu	AluSz
CAediting_1452406	chr21_38289122_+	SINE	Alu	AluSz
CAediting_1452407	chr21_38289131_+	SINE	Alu	AluSz
CAediting_1452408	chr21_38289142_+	SINE	Alu	AluSz
CAediting_1452409	chr21_38289154_+	SINE	Alu	AluSz
CAediting_1452410	chr21_38289186_+	SINE	Alu	AluSz
CAediting_1452411	chr21_38289478_+	SINE	Alu	AluSz
CAediting_1452412	chr21_38289634_+	SINE	Alu	AluSz
CAediting_1452453	chr21_38304727_+	SINE	Alu	AluY
CAediting_1452454	chr21_38304753_+	SINE	Alu	AluY
CAediting_1452455	chr21_38304805_+	SINE	Alu	AluY
CAediting_1452456	chr21_38304817_+	SINE	Alu	AluY
CAediting_1452457	chr21_38304937_+	SINE	Alu	AluSq
CAediting_1452458	chr21_38304959_+	SINE	Alu	AluSq
CAediting_1452459	chr21_38304965_+	SINE	Alu	AluSq
CAediting_1452460	chr21_38304969_+	SINE	Alu	AluSq
CAediting_1452461	chr21_38304976_+	SINE	Alu	AluSq
CAediting_1452462	chr21_38304986_+	SINE	Alu	AluSq
CAediting_1452463	chr21_38305001_+	SINE	Alu	AluSq
CAediting_1452464	chr21_38305021_+	SINE	Alu	AluSq
CAediting_1452465	chr21_38305025_+	SINE	Alu	AluSq
CAediting_1452466	chr21_38305029_+	SINE	Alu	AluSq
CAediting_1452467	chr21_38305030_+	SINE	Alu	AluSq
CAediting_1452468	chr21_38305050_+	SINE	Alu	AluSq
CAediting_1452469	chr21_38305059_+	SINE	Alu	AluSq
CAediting_1452470	chr21_38305068_+	SINE	Alu	AluSq
CAediting_1452471	chr21_38305069_+	SINE	Alu	AluSq
CAediting_1452472	chr21_38305071_+	SINE	Alu	AluSq
CAediting_1452473	chr21_38305088_+	SINE	Alu	AluSq
CAediting_1452474	chr21_38305097_+	SINE	Alu	AluSq

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RNA A-to-I editing events in the alternative splicing sites for KCNJ15

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000157551.16.KCNJ15.

Correlation between RNA A-to-I editing and PSI for ENSG00000157551.16.KCNJ15.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for KCNJ15

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for KCNJ15

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for KCNJ15

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1452446	chr21_38303730_+	ENSG00000157551.16	ENST00000328656	hsa-miR-934	38303728	38303734	7mer-m8	38303714	38303735	145.00	-13.25
CAediting_1452447	chr21_38303732_+	ENSG00000157551.16	ENST00000328656	hsa-miR-455-3p	38303730	38303736	7mer-m8	38303718	38303737	147.00	-15.79
CAediting_1452457	chr21_38304937_+	ENSG00000157551.16	ENST00000328656	hsa-miR-941	38304933	38304939	7mer-m8	38304917	38304940	154.00	-25.31
CAediting_1452457	chr21_38304937_+	ENSG00000157551.16	ENST00000328656	hsa-miR-941	38304933	38304939	7mer-m8	38304917	38304940	154.00	-25.31
CAediting_1452457	chr21_38304937_+	ENSG00000157551.16	ENST00000328656	hsa-miR-941	38304933	38304939	7mer-m8	38304917	38304940	154.00	-25.31
CAediting_1452457	chr21_38304937_+	ENSG00000157551.16	ENST00000328656	hsa-miR-941	38304933	38304939	7mer-m8	38304917	38304940	154.00	-25.31
CAediting_1452457	chr21_38304937_+	ENSG00000157551.16	ENST00000328656	hsa-miR-941	38304933	38304939	7mer-m8	38304917	38304940	154.00	-25.31
CAediting_1452458	chr21_38304959_+	ENSG00000157551.16	ENST00000328656	hsa-miR-513a-5p	38304953	38304959	7mer-m8	38304943	38304960	152.00	-19.80
CAediting_1452458	chr21_38304959_+	ENSG00000157551.16	ENST00000328656	hsa-miR-513a-5p	38304953	38304959	7mer-m8	38304943	38304960	152.00	-19.80
CAediting_1452458	chr21_38304959_+	ENSG00000157551.16	ENST00000328656	hsa-miR-638	38304958	38304964	7mer-1a	38304940	38304964	155.00	-32.67
CAediting_1452460	chr21_38304969_+	ENSG00000157551.16	ENST00000328656	hsa-miR-1207-3p	38304962	38304968	7mer-m8	38304952	38304969	140.00	-12.56
CAediting_1452460	chr21_38304969_+	ENSG00000157551.16	ENST00000328656	hsa-miR-646	38304964	38304970	7mer-m8	38304953	38304971	145.00	-14.99
CAediting_1452463	chr21_38305001_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4437	38304997	38305003	7mer-m8	38304984	38305004	146.00	-19.53
CAediting_1452464	chr21_38305021_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6784-3p	38305020	38305025	6mer	38305004	38305026	143.00	-26.64
CAediting_1452465	chr21_38305025_+	ENSG00000157551.16	ENST00000328656	hsa-miR-324-3p	38305018	38305024	7mer-m8	38305005	38305025	142.00	-21.90
CAediting_1452467	chr21_38305030_+	ENSG00000157551.16	ENST00000328656	hsa-miR-7975	38305026	38305031	6mer	38305014	38305032	142.00	-18.39
CAediting_1452414	chr21_38302900_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4761-5p	38302893	38302900	8mer-1a	38302881	38302900	148.00	-15.82
CAediting_1452418	chr21_38302927_+	ENSG00000157551.16	ENST00000328656	hsa-miR-200b-3p	38302925	38302930	6mer	38302910	38302931	143.00	-11.36
CAediting_1452418	chr21_38302927_+	ENSG00000157551.16	ENST00000328656	hsa-miR-429	38302925	38302930	6mer	38302909	38302931	149.00	-16.03
CAediting_1452418	chr21_38302927_+	ENSG00000157551.16	ENST00000328656	hsa-miR-8084	38302924	38302930	7mer-m8	38302905	38302931	164.00	-8.65
CAediting_1452424	chr21_38302968_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4680-3p	38302961	38302968	8mer-1a	38302948	38302968	143.00	-9.94
CAediting_1452425	chr21_38302972_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4482-3p	38302967	38302974	8mer-1a	38302953	38302974	145.00	-9.76
CAediting_1452429	chr21_38302985_+	ENSG00000157551.16	ENST00000328656	hsa-miR-606	38302983	38302989	7mer-m8	38302970	38302990	140.00	-6.87
CAediting_1452431	chr21_38303665_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6765-3p	38303660	38303666	7mer-m8	38303647	38303667	142.00	-18.54
CAediting_1452433	chr21_38303672_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4699-3p	38303670	38303676	7mer-m8	38303657	38303677	151.00	-9.56
CAediting_1452437	chr21_38303680_+	ENSG00000157551.16	ENST00000328656	hsa-miR-29a-5p	38303673	38303680	8mer-1a	38303659	38303680	147.00	-10.47
CAediting_1452437	chr21_38303680_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4762-3p	38303675	38303681	7mer-m8	38303658	38303682	146.00	-12.15
CAediting_1452437	chr21_38303680_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6739-3p	38303678	38303684	7mer-m8	38303666	38303685	150.00	-9.56
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-204-3p	38303716	38303722	7mer-m8	38303703	38303723	142.00	-14.99
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4646-5p	38303716	38303722	7mer-m8	38303702	38303723	144.00	-15.87
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548a-3p	38303720	38303726	7mer-m8	38303704	38303727	162.00	-9.32
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548a-3p	38303720	38303726	7mer-m8	38303704	38303727	162.00	-9.32
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548a-3p	38303720	38303726	7mer-m8	38303704	38303727	162.00	-9.32
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548ae-3p	38303721	38303728	8mer-1a	38303705	38303728	153.00	-8.52
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548ae-3p	38303721	38303728	8mer-1a	38303705	38303728	153.00	-8.52
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548ah-3p	38303721	38303728	8mer-1a	38303704	38303728	150.00	-6.57
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aj-3p	38303721	38303728	8mer-1a	38303705	38303728	153.00	-8.96
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aj-3p	38303721	38303728	8mer-1a	38303705	38303728	153.00	-8.96
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548am-3p	38303721	38303728	8mer-1a	38303704	38303728	150.00	-6.57
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aq-3p	38303721	38303728	8mer-1a	38303704	38303728	153.00	-6.46
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548ar-3p	38303720	38303726	7mer-m8	38303708	38303727	147.00	-7.43
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548az-3p	38303720	38303726	7mer-m8	38303709	38303727	143.00	-7.15
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548bc	38303720	38303726	7mer-m8	38303704	38303727	153.00	-7.84
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548e-3p	38303720	38303726	7mer-m8	38303708	38303727	151.00	-7.88
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548f-3p	38303720	38303726	7mer-m8	38303706	38303727	147.00	-7.80
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548f-3p	38303720	38303726	7mer-m8	38303706	38303727	147.00	-7.80
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548f-3p	38303720	38303726	7mer-m8	38303706	38303727	147.00	-7.80
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548f-3p	38303720	38303726	7mer-m8	38303706	38303727	147.00	-7.80
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548f-3p	38303720	38303726	7mer-m8	38303706	38303727	147.00	-7.80
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548j-3p	38303721	38303728	8mer-1a	38303708	38303728	145.00	-6.46
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548x-3p	38303721	38303728	8mer-1a	38303706	38303728	152.00	-9.64
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548x-3p	38303721	38303728	8mer-1a	38303706	38303728	152.00	-9.64
CAediting_1452448	chr21_38303748_+	ENSG00000157551.16	ENST00000328656	hsa-miR-3143	38303744	38303750	7mer-m8	38303727	38303751	164.00	-14.61
CAediting_1452449	chr21_38303751_+	ENSG00000157551.16	ENST00000328656	hsa-miR-16-2-3p	38303744	38303750	7mer-m8	38303730	38303751	140.00	-6.26
CAediting_1452449	chr21_38303751_+	ENSG00000157551.16	ENST00000328656	hsa-miR-195-3p	38303744	38303750	7mer-m8	38303729	38303751	147.00	-9.92
CAediting_1452449	chr21_38303751_+	ENSG00000157551.16	ENST00000328656	hsa-miR-338-5p	38303745	38303751	7mer-m8	38303731	38303752	140.00	-8.78
CAediting_1452452	chr21_38303767_+	ENSG00000157551.16	ENST00000328656	hsa-miR-362-5p	38303763	38303770	8mer-1a	38303747	38303770	140.00	-11.37
CAediting_1452452	chr21_38303767_+	ENSG00000157551.16	ENST00000328656	hsa-miR-500b-5p	38303763	38303770	8mer-1a	38303752	38303770	145.00	-9.56
CAediting_1452453	chr21_38304727_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4530	38304721	38304728	8mer-1a	38304711	38304728	148.00	-21.16
CAediting_1452453	chr21_38304727_+	ENSG00000157551.16	ENST00000328656	hsa-miR-508-5p	38304724	38304730	7mer-m8	38304704	38304731	147.00	-24.51
CAediting_1452453	chr21_38304727_+	ENSG00000157551.16	ENST00000328656	hsa-miR-766-3p	38304723	38304729	7mer-m8	38304708	38304730	143.00	-22.31
CAediting_1452455	chr21_38304805_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4691-3p	38304802	38304808	7mer-m8	38304782	38304809	154.00	-26.31
CAediting_1452461	chr21_38304976_+	ENSG00000157551.16	ENST00000328656	hsa-miR-125a-5p	38304969	38304975	7mer-m8	38304953	38304976	141.00	-17.93
CAediting_1452461	chr21_38304976_+	ENSG00000157551.16	ENST00000328656	hsa-miR-125b-5p	38304969	38304975	7mer-m8	38304955	38304976	141.00	-16.11
CAediting_1452461	chr21_38304976_+	ENSG00000157551.16	ENST00000328656	hsa-miR-125b-5p	38304969	38304975	7mer-m8	38304955	38304976	141.00	-16.11
CAediting_1452461	chr21_38304976_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4319	38304969	38304975	7mer-m8	38304960	38304976	142.00	-17.68
CAediting_1452466	chr21_38305029_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4695-3p	38305027	38305033	7mer-m8	38305011	38305034	154.00	-23.23
CAediting_1452466	chr21_38305029_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6787-3p	38305024	38305031	8mer-1a	38305009	38305031	159.00	-26.32
CAediting_1452468	chr21_38305050_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4743-5p	38305046	38305052	7mer-m8	38305031	38305053	147.00	-23.99
CAediting_1452421	chr21_38302949_+	ENSG00000157551.16	ENST00000328656	hsa-miR-576-5p	38302944	38302950	7mer-m8	38302930	38302951	140.00	-7.04
CAediting_1452471	chr21_38305069_+	ENSG00000157551.16	ENST00000328656	hsa-miR-3168	38305066	38305072	7mer-m8	38305057	38305073	145.00	-14.19
CAediting_1452471	chr21_38305069_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6874-3p	38305067	38305072	6mer	38305051	38305073	148.00	-16.37

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1452458	chr21_38304959_+	ENSG00000157551.16	ENST00000328656	hsa-miR-10399-5p	38304954	38304960	7mer-m8	38304940	38304961	144	-11.33
CAediting_1452461	chr21_38304976_+	ENSG00000157551.16	ENST00000328656	hsa-miR-1200	38304969	38304975	7mer-m8	38304955	38304976	141	-17.86
CAediting_1452418	chr21_38302927_+	ENSG00000157551.16	ENST00000328656	hsa-miR-16-2-3p	38302925	38302932	8mer-1a	38302910	38302932	147	-7.31
CAediting_1452419	chr21_38302929_+	ENSG00000157551.16	ENST00000328656	hsa-miR-16-2-3p	38302925	38302932	8mer-1a	38302910	38302932	147	-7.31
CAediting_1452423	chr21_38302962_+	ENSG00000157551.16	ENST00000328656	hsa-miR-183-3p	38302960	38302967	8mer-1a	38302946	38302967	140	-7.71
CAediting_1452416	chr21_38302922_+	ENSG00000157551.16	ENST00000328656	hsa-miR-190b-3p	38302917	38302923	7mer-1a	38302900	38302923	146	-7.15
CAediting_1452418	chr21_38302927_+	ENSG00000157551.16	ENST00000328656	hsa-miR-195-3p	38302925	38302932	8mer-1a	38302911	38302932	149	-7.95
CAediting_1452419	chr21_38302929_+	ENSG00000157551.16	ENST00000328656	hsa-miR-195-3p	38302925	38302932	8mer-1a	38302911	38302932	149	-7.95
CAediting_1452436	chr21_38303679_+	ENSG00000157551.16	ENST00000328656	hsa-miR-2052	38303676	38303683	8mer-1a	38303665	38303683	147	-9.78
CAediting_1452437	chr21_38303680_+	ENSG00000157551.16	ENST00000328656	hsa-miR-2052	38303676	38303683	8mer-1a	38303665	38303683	147	-9.78
CAediting_1452438	chr21_38303681_+	ENSG00000157551.16	ENST00000328656	hsa-miR-2052	38303676	38303683	8mer-1a	38303665	38303683	147	-9.78
CAediting_1452439	chr21_38303682_+	ENSG00000157551.16	ENST00000328656	hsa-miR-2052	38303676	38303683	8mer-1a	38303665	38303683	147	-9.78
CAediting_1452456	chr21_38304817_+	ENSG00000157551.16	ENST00000328656	hsa-miR-20b-3p	38304811	38304817	7mer-m8	38304796	38304818	153	-18.18
CAediting_1452468	chr21_38305050_+	ENSG00000157551.16	ENST00000328656	hsa-miR-3652	38305046	38305052	7mer-m8	38305034	38305053	148	-20.61
CAediting_1452413	chr21_38302892_+	ENSG00000157551.16	ENST00000328656	hsa-miR-3689a-5p	38302889	38302895	7mer-m8	38302875	38302896	145	-9.81
CAediting_1452413	chr21_38302892_+	ENSG00000157551.16	ENST00000328656	hsa-miR-3689b-5p	38302889	38302895	7mer-m8	38302875	38302896	145	-9.81
CAediting_1452413	chr21_38302892_+	ENSG00000157551.16	ENST00000328656	hsa-miR-3689e	38302889	38302895	7mer-m8	38302875	38302896	145	-9.81
CAediting_1452413	chr21_38302892_+	ENSG00000157551.16	ENST00000328656	hsa-miR-3689f	38302889	38302895	7mer-m8	38302874	38302896	147	-10.61
CAediting_1452445	chr21_38303723_+	ENSG00000157551.16	ENST00000328656	hsa-miR-450a-1-3p	38303716	38303722	7mer-m8	38303701	38303723	153	-11.98
CAediting_1452453	chr21_38304727_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4524a-5p	38304720	38304726	7mer-m8	38304706	38304727	147	-11.36
CAediting_1452453	chr21_38304727_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4524b-5p	38304720	38304726	7mer-m8	38304707	38304727	146	-11.14
CAediting_1452464	chr21_38305021_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4772-3p	38305015	38305021	7mer-m8	38305000	38305022	154	-17.32
CAediting_1452416	chr21_38302922_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4799-5p	38302917	38302923	7mer-m8	38302903	38302924	152	-8.86
CAediting_1452463	chr21_38305001_+	ENSG00000157551.16	ENST00000328656	hsa-miR-498-5p	38304994	38305000	7mer-m8	38304979	38305001	143	-10.8
CAediting_1452459	chr21_38304965_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5089-5p	38304958	38304964	7mer-m8	38304945	38304965	152	-18.63
CAediting_1452430	chr21_38302996_+	ENSG00000157551.16	ENST00000328656	hsa-miR-510-3p	38302990	38302996	7mer-m8	38302977	38302997	149	-11.79
CAediting_1452455	chr21_38304805_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5690	38304802	38304808	7mer-m8	38304789	38304809	145	-16.75
CAediting_1452448	chr21_38303748_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5692b	38303745	38303751	7mer-m8	38303733	38303752	142	-9.94
CAediting_1452449	chr21_38303751_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5692b	38303745	38303751	7mer-m8	38303733	38303752	142	-9.94
CAediting_1452448	chr21_38303748_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5692c	38303745	38303751	7mer-m8	38303731	38303752	144	-10.84
CAediting_1452449	chr21_38303751_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5692c	38303745	38303751	7mer-m8	38303731	38303752	144	-10.84
CAediting_1452448	chr21_38303748_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5692c	38303745	38303751	7mer-m8	38303731	38303752	144	-10.84
CAediting_1452449	chr21_38303751_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5692c	38303745	38303751	7mer-m8	38303731	38303752	144	-10.84
CAediting_1452468	chr21_38305050_+	ENSG00000157551.16	ENST00000328656	hsa-miR-5787	38305047	38305052	6mer	38305033	38305053	145	-27.69
CAediting_1452420	chr21_38302948_+	ENSG00000157551.16	ENST00000328656	hsa-miR-590-3p	38302946	38302952	7mer-m8	38302936	38302953	146	-5.25
CAediting_1452421	chr21_38302949_+	ENSG00000157551.16	ENST00000328656	hsa-miR-590-3p	38302946	38302952	7mer-m8	38302936	38302953	146	-5.25
CAediting_1452422	chr21_38302951_+	ENSG00000157551.16	ENST00000328656	hsa-miR-590-3p	38302946	38302952	7mer-m8	38302936	38302953	146	-5.25
CAediting_1452447	chr21_38303732_+	ENSG00000157551.16	ENST00000328656	hsa-miR-622	38303731	38303736	6mer	38303716	38303737	145	-20.46
CAediting_1452461	chr21_38304976_+	ENSG00000157551.16	ENST00000328656	hsa-miR-622	38304975	38304981	7mer-1a	38304959	38304981	141	-26.18
CAediting_1452458	chr21_38304959_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6504-3p	38304954	38304960	7mer-m8	38304940	38304961	152	-16.01
CAediting_1452459	chr21_38304965_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6506-5p	38304959	38304965	7mer-m8	38304944	38304966	144	-16.08
CAediting_1452417	chr21_38302926_+	ENSG00000157551.16	ENST00000328656	hsa-miR-656-3p	38302923	38302929	7mer-m8	38302910	38302930	140	-4.23
CAediting_1452418	chr21_38302927_+	ENSG00000157551.16	ENST00000328656	hsa-miR-656-3p	38302923	38302929	7mer-m8	38302910	38302930	140	-4.23
CAediting_1452419	chr21_38302929_+	ENSG00000157551.16	ENST00000328656	hsa-miR-656-3p	38302923	38302929	7mer-m8	38302910	38302930	140	-4.23
CAediting_1452456	chr21_38304817_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6720-3p	38304815	38304821	7mer-m8	38304801	38304822	152	-20.49
CAediting_1452462	chr21_38304986_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6747-3p	38304981	38304988	8mer-1a	38304968	38304988	152	-21.39
CAediting_1452457	chr21_38304937_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6765-3p	38304934	38304940	7mer-m8	38304921	38304941	153	-21.88
CAediting_1452460	chr21_38304969_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6869-5p	38304966	38304972	7mer-m8	38304951	38304973	146	-19.73
CAediting_1452458	chr21_38304959_+	ENSG00000157551.16	ENST00000328656	hsa-miR-7151-3p	38304952	38304959	8mer-1a	38304939	38304959	142	-13.54
CAediting_1452469	chr21_38305059_+	ENSG00000157551.16	ENST00000328656	hsa-miR-744-3p	38305055	38305062	8mer-1a	38305041	38305062	140	-10.2
CAediting_1452414	chr21_38302900_+	ENSG00000157551.16	ENST00000328656	hsa-miR-7856-5p	38302895	38302902	8mer-1a	38302882	38302902	140	-9.28

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000613499	hsa-miR-200b-3p	38300548	38300554	7mer-m8	38300533	38300555	146	-10.84
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000612702	hsa-miR-200b-3p	38300548	38300554	7mer-m8	38300533	38300555	146	-10.84
CAediting_748296	chr10_51299626_+	ENSG00000157551.16	ENST00000328656	hsa-miR-605-3p	38302429	38302436	8mer-1a	38302413	38302436	158	-15.5
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000328656	hsa-miR-200b-3p	38300548	38300554	7mer-m8	38300533	38300555	146	-10.84
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000398932	hsa-miR-200b-3p	38300548	38300554	7mer-m8	38300533	38300555	146	-10.84
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000398934	hsa-miR-200b-3p	38300548	38300554	7mer-m8	38300533	38300555	146	-10.84
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000398930	hsa-miR-200b-3p	38300548	38300554	7mer-m8	38300533	38300555	146	-10.84
CAediting_524911	chr7_5495852_-	ENSG00000157551.16	ENST00000613499	hsa-miR-589-3p	38301258	38301264	7mer-m8	38301243	38301265	143	-16.26
CAediting_524911	chr7_5495852_-	ENSG00000157551.16	ENST00000612702	hsa-miR-589-3p	38301258	38301264	7mer-m8	38301243	38301265	143	-16.26
CAediting_1229413	chr17_67471544_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aa	38304388	38304394	7mer-m8	38304373	38304395	155	-14.19
CAediting_1229414	chr17_67471546_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aa	38303011	38303018	8mer-1a	38302993	38303018	148	-8.12
CAediting_1229414	chr17_67471546_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aa	38306011	38306017	7mer-m8	38305993	38306018	147	-14.04
CAediting_1229415	chr17_67471547_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aa	38304006	38304012	7mer-m8	38303989	38304013	157	-10.6
CAediting_1160181	chr17_7017644_-	ENSG00000157551.16	ENST00000328656	hsa-miR-195-3p	38302208	38302214	7mer-m8	38302194	38302215	140	-11.2
CAediting_228905	chr2_188297554_+	ENSG00000157551.16	ENST00000328656	hsa-miR-561-3p	38304524	38304530	7mer-m8	38304509	38304531	158	-16.6
CAediting_396018	chr5_1062918_-	ENSG00000157551.16	ENST00000328656	hsa-miR-4635	38307098	38307103	6mer	38307083	38307104	142	-21.09
CAediting_524911	chr7_5495852_-	ENSG00000157551.16	ENST00000328656	hsa-miR-589-3p	38301258	38301264	7mer-m8	38301243	38301265	143	-16.26
CAediting_524911	chr7_5495852_-	ENSG00000157551.16	ENST00000398932	hsa-miR-589-3p	38301258	38301264	7mer-m8	38301243	38301265	143	-16.26
CAediting_524911	chr7_5495852_-	ENSG00000157551.16	ENST00000398934	hsa-miR-589-3p	38301258	38301264	7mer-m8	38301243	38301265	143	-16.26
CAediting_524911	chr7_5495852_-	ENSG00000157551.16	ENST00000398930	hsa-miR-589-3p	38301258	38301264	7mer-m8	38301243	38301265	143	-16.26

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000613499	hsa-miR-200b-3p	38300802	38300808	7mer-m8	38300788	38300809	149	-8.61
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000612702	hsa-miR-200b-3p	38300802	38300808	7mer-m8	38300788	38300809	149	-8.61
CAediting_846604	chr11_93733708_-	ENSG00000157551.16	ENST00000328656	hsa-miR-1304-3p	38306002	38306007	6mer	38305985	38306008	146	-19.92
CAediting_1160181	chr17_7017644_-	ENSG00000157551.16	ENST00000328656	hsa-miR-195-3p	38302874	38302880	7mer-m8	38302860	38302881	151	-9.29
CAediting_1160181	chr17_7017644_-	ENSG00000157551.16	ENST00000328656	hsa-miR-195-3p	38302925	38302932	8mer-1a	38302911	38302932	149	-7.95
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000328656	hsa-miR-200b-3p	38302689	38302695	7mer-m8	38302677	38302696	153	-7.29
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000328656	hsa-miR-200b-3p	38300802	38300808	7mer-m8	38300788	38300809	149	-8.61
CAediting_688080	chr9_63819626_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4477b	38302536	38302543	8mer-1a	38302524	38302543	147	-8.73
CAediting_688080	chr9_63819626_+	ENSG00000157551.16	ENST00000328656	hsa-miR-4477b	38306366	38306373	8mer-1a	38306352	38306373	151	-8.92
CAediting_396018	chr5_1062918_-	ENSG00000157551.16	ENST00000328656	hsa-miR-4635	38302100	38302106	7mer-m8	38302085	38302107	149	-15.5
CAediting_1229413	chr17_67471544_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aa	38304352	38304358	7mer-m8	38304332	38304359	152	-10.79
CAediting_1229414	chr17_67471546_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aa	38304352	38304358	7mer-m8	38304332	38304359	152	-10.79
CAediting_1229415	chr17_67471547_+	ENSG00000157551.16	ENST00000328656	hsa-miR-548aa	38304352	38304358	7mer-m8	38304332	38304359	152	-10.79
CAediting_117844	chr1_162342605_+	ENSG00000157551.16	ENST00000328656	hsa-miR-556-3p	38300883	38300889	7mer-m8	38300869	38300890	155	-12.95
CAediting_748296	chr10_51299626_+	ENSG00000157551.16	ENST00000328656	hsa-miR-605-3p	38306244	38306250	7mer-m8	38306222	38306251	145	-18.24
CAediting_1351755	chr19_40282625_-	ENSG00000157551.16	ENST00000328656	hsa-miR-641	38305646	38305653	8mer-1a	38305628	38305653	145	-11.9
CAediting_580943	chr7_100356700_+	ENSG00000157551.16	ENST00000328656	hsa-miR-6840-3p	38303575	38303581	7mer-m8	38303562	38303582	142	-20.1
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000398932	hsa-miR-200b-3p	38300802	38300808	7mer-m8	38300788	38300809	149	-8.61
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000398934	hsa-miR-200b-3p	38300802	38300808	7mer-m8	38300788	38300809	149	-8.61
CAediting_393	chr1_1167164_+	ENSG00000157551.16	ENST00000398930	hsa-miR-200b-3p	38300802	38300808	7mer-m8	38300788	38300809	149	-8.61

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for KCNJ15

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for KCNJ15

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
THCA	CAediting_1452416	chr21_38302922_+	3.28736094396982e-05	0.360986284863891	.	.	.	.
KIRC	CAediting_1452416	chr21_38302922_+	0.0352740344660713	0.195688045139612	.	.	.	.
THCA	CAediting_1452442	chr21_38303688_+	2.38934026376745e-07	0.320336808304713	.	.	.	.
KIRC	CAediting_1452442	chr21_38303688_+	3.66660011602827e-05	0.427285100978388	.	.	.	.
KIRP	CAediting_1452442	chr21_38303688_+	0.000970547666207399	0.355585389691856	.	.	.	.
THCA	CAediting_1452446	chr21_38303730_+	9.95602624130354e-05	0.315437574538243	.	.	.	.
KIRC	CAediting_1452446	chr21_38303730_+	0.000336112840563921	0.4583819791109	.	.	.	.
THCA	CAediting_1452447	chr21_38303732_+	2.25793637776015e-08	0.388073439555296	.	.	.	.
KIRC	CAediting_1452447	chr21_38303732_+	0.0225554187575335	0.284791323251952	.	.	.	.
THCA	CAediting_1452460	chr21_38304969_+	0.00610724277515894	0.171951663367253	.	.	.	.
KIRC	CAediting_1452460	chr21_38304969_+	0.044655761458531	0.221012042641505	.	.	.	.
THCA	CAediting_1452464	chr21_38305021_+	0.00812724134128884	0.156499790963892	.	.	.	.
KIRC	CAediting_1452464	chr21_38305021_+	0.019062774751282	0.246726603471347	.	.	.	.
THCA	CAediting_1452467	chr21_38305030_+	1.54722738795492e-07	0.258047512249638	.	.	.	.
KIRP	CAediting_1452467	chr21_38305030_+	.	.	0.0336508952799767	0.170749366447854	.	.

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Relation with cancer stages for KCNJ15

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRC	pathologic_stage	CAediting_1452416	chr21_38302922_+	0.0288668335975771	0.203862274641898
KIRP	clinical_stage	CAediting_1452442	chr21_38303688_+	0.0178606890858816	0.312729817967887
KIRP	clinical_stage	CAediting_1452447	chr21_38303732_+	0.00412141305829066	0.38775035595247
KIRP	clinical_stage	CAediting_1452464	chr21_38305021_+	0.0238312065139564	0.275893250821348
KIRP	pathologic_stage	CAediting_1452447	chr21_38303732_+	0.00518576487989272	0.32388238045279
KIRP	pathologic_stage	CAediting_1452464	chr21_38305021_+	0.00599443016448809	0.308511403808907
THCA	pathologic_stage	CAediting_1452442	chr21_38303688_+	0.0256946198566787	0.14223094132447
THCA	pathologic_stage	CAediting_1452446	chr21_38303730_+	0.0216513494532433	0.189952809001237
THCA	pathologic_stage	CAediting_1452447	chr21_38303732_+	0.00039765358645958	0.253074620162533
THCA	pathologic_stage	CAediting_1452460	chr21_38304969_+	0.00160562017989178	0.19893158224264
THCA	pathologic_stage	CAediting_1452464	chr21_38305021_+	0.00220704405705471	0.181880783495235

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Relation with survival for KCNJ15

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for KCNJ15

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
KCNJ15	Q99712	DB01392	Yohimbine	ATP-sensitive inward rectifier potassium channel 15	SmallMoleculeDrug	approved\|investigational\|vet_approved
KCNJ15	Q99712	DB11148	Butamben	ATP-sensitive inward rectifier potassium channel 15	SmallMoleculeDrug	approved\|withdrawn

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RelatedDiseases for KCNJ15

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
KCNJ15	C0087031	Juvenile-Onset Still Disease	1	CTD_human
KCNJ15	C3495559	Juvenile arthritis	1	CTD_human
KCNJ15	C3714758	Juvenile psoriatic arthritis	1	CTD_human
KCNJ15	C4552091	Polyarthritis, Juvenile, Rheumatoid Factor Negative	1	CTD_human
KCNJ15	C4704862	Polyarthritis, Juvenile, Rheumatoid Factor Positive	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene