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Editing gene: HSD11B1L (CAeditome ID:374875)

Gene summary for HSD11B1L

Gene summary

Gene information	Gene symbol	HSD11B1L
	Gene ID	374875
	Gene name	hydroxysteroid 11-beta dehydrogenase 1 like
	Synonyms	11-DH3\|11-beta-HSD3\|HSD1L\|HSD3\|SCDR10\|SCDR10B\|SDR26C2
	Cytomap	19p13.3
	Type of gene	protein-coding
	Description	hydroxysteroid 11-beta-dehydrogenase 1-like protein11-beta-hydroxysteroid dehydrogenase type 3short chain dehydrogenase/reductase 10short chain dehydrogenase/reductase family 26C member 2
	Modification date	20210518
	UniProtAcc	Q7Z5J1
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
HSD11B1L	GO:0005654	Hydroxysteroid 11-beta-dehydrogenase 1-like protein	0000052
HSD11B1L	GO:0043231	Hydroxysteroid 11-beta-dehydrogenase 1-like protein	0000052

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RNA A-to-I events for HSD11B1L

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000167733.12

RNA A-to-I editing events in Cancer.

CAediting_1279799(5682918, +), CAediting_1279800(5682919, +), CAediting_1279801(5682960, +), CAediting_1279802(5682961, +), CAediting_1279803(5682964, +), CAediting_1279804(5682973, +), CAediting_1279805(5683001, +), CAediting_1279806(5683029, +), CAediting_1279807(5683031, +), CAediting_1279808(5683051, +), CAediting_1279809(5683063, +), CAediting_1279810(5683069, +), CAediting_1279811(5683089, +), CAediting_1279812(5683111, +), CAediting_1279813(5683136, +), CAediting_1279814(5683198, +), CAediting_1279815(5683199, +), CAediting_1279816(5683618, +), CAediting_1279817(5683630, +), CAediting_1279818(5683637, +), CAediting_1279819(5683691, +), CAediting_1279820(5683692, +), CAediting_1279821(5683710, +), CAediting_1279822(5683736, +), CAediting_1279823(5683745, +), CAediting_1279824(5683773, +), CAediting_1279825(5683796, +), CAediting_1279826(5683814, +), CAediting_1279827(5683819, +), CAediting_1279828(5683820, +), CAediting_1279829(5683822, +), CAediting_1279830(5683843, +), CAediting_1279831(5683876, +), CAediting_1279832(5684053, +), CAediting_1279833(5684055, +), CAediting_1279834(5684056, +), CAediting_1279835(5684069, +), CAediting_1279836(5684075, +), CAediting_1279837(5684076, +), CAediting_1279838(5684145, +), CAediting_1279839(5684157, +), CAediting_1279840(5684199, +), CAediting_1279841(5684225, +), CAediting_1279842(5684238, +), CAediting_1279843(5684251, +), CAediting_1279844(5684255, +), CAediting_1279845(5684268, +), CAediting_1279846(5684278, +), CAediting_1279847(5684296, +), CAediting_1279848(5684299, +), CAediting_1279849(5685314, +), CAediting_1279850(5685326, +), CAediting_1279851(5685374, +), CAediting_1279852(5685380, +), CAediting_1279853(5685411, +), CAediting_1279854(5685414, +), CAediting_1279855(5685418, +), CAediting_1279856(5685423, +), CAediting_1279857(5685429, +), CAediting_1279858(5685434, +), CAediting_1279859(5685456, +), CAediting_1279860(5685457, +), CAediting_1279861(5685473, +), CAediting_1279862(5685479, +), CAediting_1279863(5685502, +), CAediting_1279864(5685512, +), CAediting_1279865(5685513, +), CAediting_1279866(5685526, +), CAediting_1279867(5685617, +), CAediting_1279868(5685659, +),

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RNA editing positional annotations for HSD11B1L using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_1279849	chr19_5685314_+	nonsynonymous SNV	ENST00000422535.5	c.A217G	p.T73A	D	.	N

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1279799	chr19_5682918_+	ncRNA_intronic
CAediting_1279800	chr19_5682919_+	ncRNA_intronic
CAediting_1279801	chr19_5682960_+	ncRNA_intronic
CAediting_1279802	chr19_5682961_+	ncRNA_intronic
CAediting_1279803	chr19_5682964_+	ncRNA_intronic
CAediting_1279804	chr19_5682973_+	ncRNA_intronic
CAediting_1279805	chr19_5683001_+	ncRNA_intronic
CAediting_1279806	chr19_5683029_+	ncRNA_intronic
CAediting_1279807	chr19_5683031_+	ncRNA_intronic
CAediting_1279808	chr19_5683051_+	ncRNA_intronic
CAediting_1279809	chr19_5683063_+	ncRNA_intronic
CAediting_1279810	chr19_5683069_+	ncRNA_intronic
CAediting_1279811	chr19_5683089_+	ncRNA_intronic
CAediting_1279812	chr19_5683111_+	ncRNA_intronic
CAediting_1279813	chr19_5683136_+	ncRNA_intronic
CAediting_1279814	chr19_5683198_+	ncRNA_intronic
CAediting_1279815	chr19_5683199_+	ncRNA_intronic
CAediting_1279816	chr19_5683618_+	ncRNA_intronic
CAediting_1279817	chr19_5683630_+	ncRNA_intronic
CAediting_1279818	chr19_5683637_+	ncRNA_intronic
CAediting_1279819	chr19_5683691_+	ncRNA_intronic
CAediting_1279820	chr19_5683692_+	ncRNA_intronic
CAediting_1279821	chr19_5683710_+	ncRNA_intronic
CAediting_1279822	chr19_5683736_+	ncRNA_intronic
CAediting_1279823	chr19_5683745_+	ncRNA_intronic
CAediting_1279824	chr19_5683773_+	ncRNA_intronic
CAediting_1279825	chr19_5683796_+	ncRNA_intronic
CAediting_1279826	chr19_5683814_+	ncRNA_intronic
CAediting_1279827	chr19_5683819_+	ncRNA_intronic
CAediting_1279828	chr19_5683820_+	ncRNA_intronic
CAediting_1279829	chr19_5683822_+	ncRNA_intronic
CAediting_1279830	chr19_5683843_+	ncRNA_intronic
CAediting_1279831	chr19_5683876_+	ncRNA_intronic
CAediting_1279832	chr19_5684053_+	exonic
CAediting_1279833	chr19_5684055_+	exonic
CAediting_1279834	chr19_5684056_+	exonic
CAediting_1279835	chr19_5684069_+	exonic
CAediting_1279836	chr19_5684075_+	exonic
CAediting_1279837	chr19_5684076_+	exonic
CAediting_1279838	chr19_5684145_+	ncRNA_intronic
CAediting_1279839	chr19_5684157_+	ncRNA_intronic
CAediting_1279840	chr19_5684199_+	splicing
CAediting_1279841	chr19_5684225_+	ncRNA_intronic
CAediting_1279842	chr19_5684238_+	ncRNA_intronic
CAediting_1279843	chr19_5684251_+	ncRNA_intronic
CAediting_1279844	chr19_5684255_+	ncRNA_intronic
CAediting_1279845	chr19_5684268_+	ncRNA_intronic
CAediting_1279846	chr19_5684278_+	ncRNA_intronic
CAediting_1279847	chr19_5684296_+	ncRNA_intronic
CAediting_1279848	chr19_5684299_+	ncRNA_intronic
CAediting_1279849	chr19_5685314_+	exonic
CAediting_1279850	chr19_5685326_+	exonic
CAediting_1279851	chr19_5685374_+	ncRNA_intronic
CAediting_1279852	chr19_5685380_+	ncRNA_intronic
CAediting_1279853	chr19_5685411_+	ncRNA_intronic
CAediting_1279854	chr19_5685414_+	ncRNA_intronic
CAediting_1279855	chr19_5685418_+	ncRNA_intronic
CAediting_1279856	chr19_5685423_+	ncRNA_intronic
CAediting_1279857	chr19_5685429_+	ncRNA_intronic
CAediting_1279858	chr19_5685434_+	ncRNA_intronic
CAediting_1279859	chr19_5685456_+	ncRNA_intronic
CAediting_1279860	chr19_5685457_+	ncRNA_intronic
CAediting_1279861	chr19_5685473_+	ncRNA_intronic
CAediting_1279862	chr19_5685479_+	ncRNA_intronic
CAediting_1279863	chr19_5685502_+	ncRNA_intronic
CAediting_1279864	chr19_5685512_+	ncRNA_intronic
CAediting_1279865	chr19_5685513_+	ncRNA_intronic
CAediting_1279866	chr19_5685526_+	ncRNA_intronic
CAediting_1279867	chr19_5685617_+	ncRNA_intronic
CAediting_1279868	chr19_5685659_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1279799	chr19_5682918_+	SINE	Alu	AluSx
CAediting_1279800	chr19_5682919_+	SINE	Alu	AluSx
CAediting_1279801	chr19_5682960_+	SINE	Alu	AluJo
CAediting_1279802	chr19_5682961_+	SINE	Alu	AluJo
CAediting_1279803	chr19_5682964_+	SINE	Alu	AluJo
CAediting_1279804	chr19_5682973_+	SINE	Alu	AluJo
CAediting_1279805	chr19_5683001_+	SINE	Alu	AluJo
CAediting_1279806	chr19_5683029_+	SINE	Alu	AluSx
CAediting_1279807	chr19_5683031_+	SINE	Alu	AluSx
CAediting_1279808	chr19_5683051_+	SINE	Alu	AluSx
CAediting_1279809	chr19_5683063_+	SINE	Alu	AluSx
CAediting_1279810	chr19_5683069_+	SINE	Alu	AluSx
CAediting_1279811	chr19_5683089_+	SINE	Alu	AluSx
CAediting_1279812	chr19_5683111_+	SINE	Alu	AluSx
CAediting_1279813	chr19_5683136_+	SINE	Alu	AluSx
CAediting_1279814	chr19_5683198_+	SINE	Alu	AluSp
CAediting_1279815	chr19_5683199_+	SINE	Alu	AluSp
CAediting_1279816	chr19_5683618_+	SINE	Alu	AluJo
CAediting_1279817	chr19_5683630_+	SINE	Alu	AluJo
CAediting_1279818	chr19_5683637_+	SINE	Alu	AluJo
CAediting_1279819	chr19_5683691_+	SINE	Alu	AluJo
CAediting_1279820	chr19_5683692_+	SINE	Alu	AluJo
CAediting_1279821	chr19_5683710_+	SINE	Alu	AluJo
CAediting_1279822	chr19_5683736_+	SINE	Alu	AluJo
CAediting_1279823	chr19_5683745_+	SINE	Alu	AluJo
CAediting_1279824	chr19_5683773_+	SINE	Alu	AluJo
CAediting_1279825	chr19_5683796_+	SINE	Alu	AluJo
CAediting_1279826	chr19_5683814_+	SINE	Alu	AluJo
CAediting_1279827	chr19_5683819_+	SINE	Alu	AluJo
CAediting_1279828	chr19_5683820_+	SINE	Alu	AluJo
CAediting_1279829	chr19_5683822_+	SINE	Alu	AluJo
CAediting_1279830	chr19_5683843_+	SINE	Alu	AluJo
CAediting_1279831	chr19_5683876_+	SINE	Alu	AluJo
CAediting_1279832	chr19_5684053_+	SINE	Alu	AluSq2
CAediting_1279833	chr19_5684055_+	SINE	Alu	AluSq2
CAediting_1279834	chr19_5684056_+	SINE	Alu	AluSq2
CAediting_1279835	chr19_5684069_+	SINE	Alu	AluSq2
CAediting_1279836	chr19_5684075_+	SINE	Alu	AluSq2
CAediting_1279837	chr19_5684076_+	SINE	Alu	AluSq2
CAediting_1279838	chr19_5684145_+	SINE	Alu	AluSq2
CAediting_1279839	chr19_5684157_+	SINE	Alu	AluSq2
CAediting_1279840	chr19_5684199_+	SINE	Alu	AluSq2
CAediting_1279841	chr19_5684225_+	SINE	Alu	AluSq2
CAediting_1279842	chr19_5684238_+	SINE	Alu	AluSq2
CAediting_1279843	chr19_5684251_+	SINE	Alu	AluSq2
CAediting_1279844	chr19_5684255_+	SINE	Alu	AluSq2
CAediting_1279845	chr19_5684268_+	SINE	Alu	AluSq2
CAediting_1279846	chr19_5684278_+	SINE	Alu	AluSq2
CAediting_1279847	chr19_5684296_+	SINE	Alu	AluSq2
CAediting_1279848	chr19_5684299_+	SINE	Alu	AluSq2
CAediting_1279849	chr19_5685314_+	SINE	Alu	AluSx
CAediting_1279850	chr19_5685326_+	SINE	Alu	AluSx
CAediting_1279851	chr19_5685374_+	SINE	Alu	AluSx
CAediting_1279852	chr19_5685380_+	SINE	Alu	AluSx
CAediting_1279853	chr19_5685411_+	SINE	Alu	AluSx
CAediting_1279854	chr19_5685414_+	SINE	Alu	AluSx
CAediting_1279855	chr19_5685418_+	SINE	Alu	AluSx
CAediting_1279856	chr19_5685423_+	SINE	Alu	AluSx
CAediting_1279857	chr19_5685429_+	SINE	Alu	AluSx
CAediting_1279858	chr19_5685434_+	SINE	Alu	AluSx1
CAediting_1279859	chr19_5685456_+	SINE	Alu	AluSx1
CAediting_1279860	chr19_5685457_+	SINE	Alu	AluSx1
CAediting_1279861	chr19_5685473_+	SINE	Alu	AluSx1
CAediting_1279862	chr19_5685479_+	SINE	Alu	AluSx1
CAediting_1279863	chr19_5685502_+	SINE	Alu	AluSx1
CAediting_1279864	chr19_5685512_+	SINE	Alu	AluSx1
CAediting_1279865	chr19_5685513_+	SINE	Alu	AluSx1
CAediting_1279866	chr19_5685526_+	SINE	Alu	AluSx1
CAediting_1279867	chr19_5685617_+	SINE	Alu	AluSx1
CAediting_1279868	chr19_5685659_+	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for HSD11B1L

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_1279840	chr19_5684199_+	5684180:5684202	3SS	0+1i	TAATTTTTGTATTTTTAATAGAG	-11.07	TAATTTTTGTATTTTTAATGGAG	-2.32

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000167733.12.HSD11B1L.

Correlation between RNA A-to-I editing and PSI for ENSG00000167733.12.HSD11B1L.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HSD11B1L

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for HSD11B1L

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for HSD11B1L

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1279854	chr19_5685414_+	ENSG00000167733.12	ENST00000422535	hsa-miR-222-5p	5685408	5685414	7mer-m8	5685392	5685415	144.00	-21.26
CAediting_1279854	chr19_5685414_+	ENSG00000167733.12	ENST00000422535	hsa-miR-4797-3p	5685409	5685416	8mer-1a	5685397	5685416	144.00	-15.84
CAediting_1279855	chr19_5685418_+	ENSG00000167733.12	ENST00000422535	hsa-miR-2355-3p	5685416	5685423	8mer-1a	5685404	5685423	149.00	-16.78
CAediting_1279855	chr19_5685418_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3909	5685414	5685421	8mer-1a	5685400	5685421	143.00	-20.19
CAediting_1279855	chr19_5685418_+	ENSG00000167733.12	ENST00000422535	hsa-miR-6852-3p	5685414	5685421	8mer-1a	5685405	5685421	140.00	-13.78
CAediting_1279855	chr19_5685418_+	ENSG00000167733.12	ENST00000422535	hsa-miR-6881-3p	5685413	5685419	7mer-m8	5685399	5685420	140.00	-11.80
CAediting_1279856	chr19_5685423_+	ENSG00000167733.12	ENST00000422535	hsa-miR-4743-3p	5685418	5685425	8mer-1a	5685406	5685425	163.00	-18.30
CAediting_1279856	chr19_5685423_+	ENSG00000167733.12	ENST00000422535	hsa-miR-6888-3p	5685417	5685424	8mer-1a	5685404	5685424	143.00	-9.52
CAediting_1279857	chr19_5685429_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3136-3p	5685426	5685433	8mer-1a	5685411	5685433	142.00	-14.71
CAediting_1279857	chr19_5685429_+	ENSG00000167733.12	ENST00000422535	hsa-miR-7155-3p	5685426	5685433	8mer-1a	5685415	5685433	140.00	-14.78
CAediting_1279859	chr19_5685456_+	ENSG00000167733.12	ENST00000422535	hsa-miR-513a-5p	5685450	5685456	7mer-m8	5685440	5685457	152.00	-17.32
CAediting_1279859	chr19_5685456_+	ENSG00000167733.12	ENST00000422535	hsa-miR-513a-5p	5685450	5685456	7mer-m8	5685440	5685457	152.00	-17.32
CAediting_1279860	chr19_5685457_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3117-3p	5685455	5685461	7mer-m8	5685440	5685462	149.00	-17.82
CAediting_1279860	chr19_5685457_+	ENSG00000167733.12	ENST00000422535	hsa-miR-4759	5685454	5685461	8mer-1a	5685441	5685461	149.00	-15.31
CAediting_1279862	chr19_5685479_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3176	5685472	5685478	7mer-m8	5685461	5685479	140.00	-15.24
CAediting_1279862	chr19_5685479_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3922-3p	5685472	5685478	7mer-m8	5685458	5685479	141.00	-17.02
CAediting_1279864	chr19_5685512_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3663-5p	5685510	5685516	7mer-m8	5685501	5685517	141.00	-19.69
CAediting_1279866	chr19_5685526_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3190-5p	5685519	5685525	7mer-m8	5685507	5685526	147.00	-16.73
CAediting_1279853	chr19_5685411_+	ENSG00000167733.12	ENST00000422535	hsa-miR-374b-3p	5685408	5685414	7mer-m8	5685394	5685415	141.00	-13.25
CAediting_1279865	chr19_5685513_+	ENSG00000167733.12	ENST00000422535	hsa-miR-5580-5p	5685511	5685517	7mer-m8	5685497	5685518	140.00	-14.27

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1279859	chr19_5685456_+	ENSG00000167733.12	ENST00000422535	hsa-miR-10399-5p	5685451	5685457	7mer-m8	5685437	5685458	144	-10.26
CAediting_1279860	chr19_5685457_+	ENSG00000167733.12	ENST00000422535	hsa-miR-10399-5p	5685451	5685457	7mer-m8	5685437	5685458	144	-10.26
CAediting_1279861	chr19_5685473_+	ENSG00000167733.12	ENST00000422535	hsa-miR-150-5p	5685467	5685473	7mer-m8	5685453	5685474	140	-15.8
CAediting_1279864	chr19_5685512_+	ENSG00000167733.12	ENST00000422535	hsa-miR-2052	5685507	5685513	7mer-m8	5685495	5685514	140	-5.37
CAediting_1279865	chr19_5685513_+	ENSG00000167733.12	ENST00000422535	hsa-miR-2052	5685507	5685513	7mer-m8	5685495	5685514	140	-5.37
CAediting_1279864	chr19_5685512_+	ENSG00000167733.12	ENST00000422535	hsa-miR-29b-1-5p	5685510	5685516	7mer-m8	5685493	5685517	144	-16.09
CAediting_1279865	chr19_5685513_+	ENSG00000167733.12	ENST00000422535	hsa-miR-29b-1-5p	5685510	5685516	7mer-m8	5685493	5685517	144	-16.09
CAediting_1279858	chr19_5685434_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3176	5685428	5685434	7mer-m8	5685417	5685435	142	-15.68
CAediting_1279852	chr19_5685380_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3663-5p	5685375	5685380	6mer	5685365	5685381	141	-19.69
CAediting_1279858	chr19_5685434_+	ENSG00000167733.12	ENST00000422535	hsa-miR-3922-3p	5685428	5685434	7mer-m8	5685415	5685435	150	-17.72
CAediting_1279866	chr19_5685526_+	ENSG00000167733.12	ENST00000422535	hsa-miR-4716-5p	5685524	5685530	7mer-m8	5685510	5685531	140	-11.3
CAediting_1279857	chr19_5685429_+	ENSG00000167733.12	ENST00000422535	hsa-miR-4735-5p	5685423	5685429	7mer-m8	5685409	5685430	140	-12.92
CAediting_1279857	chr19_5685429_+	ENSG00000167733.12	ENST00000422535	hsa-miR-4775	5685422	5685428	7mer-m8	5685408	5685429	155	-8.29
CAediting_1279866	chr19_5685526_+	ENSG00000167733.12	ENST00000422535	hsa-miR-4781-3p	5685522	5685528	7mer-m8	5685511	5685529	144	-13.86
CAediting_1279852	chr19_5685380_+	ENSG00000167733.12	ENST00000422535	hsa-miR-6131	5685375	5685381	7mer-m8	5685364	5685382	140	-17.94
CAediting_1279855	chr19_5685418_+	ENSG00000167733.12	ENST00000422535	hsa-miR-6740-3p	5685414	5685421	8mer-1a	5685400	5685421	140	-13.58
CAediting_1279861	chr19_5685473_+	ENSG00000167733.12	ENST00000422535	hsa-miR-6778-3p	5685469	5685475	7mer-m8	5685456	5685476	143	-13.97
CAediting_1279853	chr19_5685411_+	ENSG00000167733.12	ENST00000422535	hsa-miR-6832-5p	5685405	5685411	7mer-m8	5685390	5685412	140	-15.54
CAediting_1279861	chr19_5685473_+	ENSG00000167733.12	ENST00000422535	hsa-miR-6878-3p	5685471	5685478	8mer-1a	5685458	5685478	142	-17.1
CAediting_1279859	chr19_5685456_+	ENSG00000167733.12	ENST00000422535	hsa-miR-7151-3p	5685449	5685456	8mer-1a	5685440	5685456	146	-17.62

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000167733.12	ENST00000422535	hsa-miR-624-3p	5685535	5685541	7mer-m8	5685522	5685542	152	-13.11
CAediting_748296	chr10_51299626_+	ENSG00000167733.12	ENST00000578046	hsa-miR-605-3p	5687735	5687741	7mer-m8	5687720	5687742	153	-19.21
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000577917	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000577917	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000581893	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000581893	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000411793	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000411793	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000301382	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000301382	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000581773	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000339423	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000339423	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000423665	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000423665	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000583928	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000579562	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000579562	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000342970	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000342970	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000581521	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000616276	hsa-miR-197-5p	5688261	5688267	7mer-1a	5688261	5688285	143	-34.37
CAediting_228905	chr2_188297554_+	ENSG00000167733.12	ENST00000616276	hsa-miR-561-3p	5688503	5688509	7mer-m8	5688490	5688510	158	-13.85
CAediting_1524209	chrX_134546392_-	ENSG00000167733.12	ENST00000582346	hsa-miR-503-5p	5687318	5687324	7mer-m8	5687297	5687325	142	-23.27
CAediting_1524209	chrX_134546392_-	ENSG00000167733.12	ENST00000584904	hsa-miR-503-5p	5687318	5687324	7mer-m8	5687297	5687325	142	-23.27
CAediting_1524209	chrX_134546392_-	ENSG00000167733.12	ENST00000579562	hsa-miR-503-5p	5687318	5687324	7mer-m8	5687297	5687325	142	-23.27

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_86358	chr1_109598906_+	ENSG00000167733.12	ENST00000579562	hsa-miR-197-5p	5687838	5687844	7mer-m8	5687822	5687845	150	-25.41

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for HSD11B1L

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for HSD11B1L

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for HSD11B1L

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

Top

Relation with survival for HSD11B1L

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

Top

RelatedDrugs for HSD11B1L

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for HSD11B1L

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene