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Editing gene: STT3A (CAeditome ID:3703)

Gene summary for STT3A

Gene summary

Gene information	Gene symbol	STT3A
	Gene ID	3703
	Gene name	STT3 oligosaccharyltransferase complex catalytic subunit A
	Synonyms	ITM1\|STT3-A\|TMC
	Cytomap	11q24.2
	Type of gene	protein-coding
	Description	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3AB5STT3, subunit of the oligosaccharyltransferase complex, homolog ASTT3A, catalytic subunit of the oligosaccharyltransferase complexSTT3A, subunit of the oligosaccharyltransfe
	Modification date	20210518
	UniProtAcc	P46977
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
STT3A	GO:0008250	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	22467853

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RNA A-to-I events for STT3A

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000134910.11

RNA A-to-I editing events in Cancer.

CAediting_858720(125598091, +), CAediting_858721(125598101, +), CAediting_858722(125598106, +), CAediting_858723(125598118, +), CAediting_858724(125598132, +), CAediting_858725(125598133, +), CAediting_858726(125601544, +), CAediting_858727(125610086, +), CAediting_858728(125610162, +), CAediting_858729(125610163, +), CAediting_858730(125610167, +), CAediting_858731(125610192, +), CAediting_858732(125610199, +), CAediting_858733(125610202, +), CAediting_858734(125610204, +), CAediting_858735(125610215, +), CAediting_858736(125610265, +), CAediting_858737(125610291, +), CAediting_858738(125610299, +), CAediting_858739(125610300, +), CAediting_858740(125610303, +), CAediting_858741(125610339, +), CAediting_858742(125610432, +), CAediting_858743(125610434, +), CAediting_858744(125610436, +), CAediting_858745(125610447, +), CAediting_858746(125610448, +), CAediting_858747(125610461, +), CAediting_858748(125610463, +), CAediting_858749(125610464, +), CAediting_858750(125610477, +), CAediting_858751(125610494, +), CAediting_858752(125610499, +), CAediting_858753(125610503, +), CAediting_858754(125610504, +), CAediting_858755(125610509, +), CAediting_858756(125610512, +), CAediting_858757(125610513, +), CAediting_858758(125610533, +), CAediting_858759(125610537, +), CAediting_858760(125610583, +), CAediting_858761(125610588, +), CAediting_858762(125610590, +), CAediting_858763(125610596, +), CAediting_858764(125610597, +), CAediting_858765(125610605, +), CAediting_858766(125610612, +), CAediting_858767(125610613, +), CAediting_858768(125610619, +), CAediting_858769(125610642, +), CAediting_858770(125610650, +), CAediting_858771(125610651, +), CAediting_858772(125610653, +), CAediting_858773(125610665, +), CAediting_858774(125610668, +), CAediting_858775(125610670, +), CAediting_858776(125610699, +), CAediting_858777(125610779, +), CAediting_858778(125610783, +), CAediting_858779(125610786, +), CAediting_858780(125610789, +), CAediting_858781(125610802, +), CAediting_858782(125610809, +), CAediting_858783(125610815, +), CAediting_858784(125610821, +), CAediting_858785(125610825, +), CAediting_858786(125610832, +), CAediting_858787(125610838, +), CAediting_858788(125610844, +), CAediting_858789(125610845, +), CAediting_858790(125610851, +), CAediting_858791(125610856, +), CAediting_858792(125610893, +), CAediting_858793(125612110, +), CAediting_858794(125615578, +), CAediting_858795(125615592, +), CAediting_858796(125615635, +), CAediting_858797(125615639, +), CAediting_858798(125615641, +), CAediting_858799(125615654, +), CAediting_858800(125616195, +), CAediting_858801(125616229, +), CAediting_858802(125616233, +), CAediting_858803(125616236, +), CAediting_858804(125616701, +), CAediting_858805(125621857, +), CAediting_858806(125621888, +), CAediting_858807(125621892, +), CAediting_858808(125621950, +), CAediting_858809(125621974, +), CAediting_858810(125621980, +), CAediting_858811(125621981, +), CAediting_858812(125622606, +), CAediting_858813(125622612, +), CAediting_858814(125622628, +), CAediting_858815(125622634, +), CAediting_858816(125622655, +), CAediting_858817(125622674, +), CAediting_858818(125622683, +), CAediting_858819(125622912, +), CAediting_858820(125624541, +), CAediting_858821(125624783, +), CAediting_858822(125624808, +), CAediting_858823(125624809, +), CAediting_858824(125624812, +), CAediting_858825(125624816, +), CAediting_858826(125624822, +), CAediting_858827(125624962, +), CAediting_858828(125624964, +),

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RNA editing positional annotations for STT3A using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_858720	chr11_125598091_+	ncRNA_intronic
CAediting_858721	chr11_125598101_+	ncRNA_intronic
CAediting_858722	chr11_125598106_+	ncRNA_intronic
CAediting_858723	chr11_125598118_+	ncRNA_intronic
CAediting_858724	chr11_125598132_+	ncRNA_intronic
CAediting_858725	chr11_125598133_+	ncRNA_intronic
CAediting_858726	chr11_125601544_+	ncRNA_intronic
CAediting_858727	chr11_125610086_+	ncRNA_intronic
CAediting_858728	chr11_125610162_+	ncRNA_intronic
CAediting_858729	chr11_125610163_+	ncRNA_intronic
CAediting_858730	chr11_125610167_+	ncRNA_intronic
CAediting_858731	chr11_125610192_+	ncRNA_intronic
CAediting_858732	chr11_125610199_+	ncRNA_intronic
CAediting_858733	chr11_125610202_+	ncRNA_intronic
CAediting_858734	chr11_125610204_+	ncRNA_intronic
CAediting_858735	chr11_125610215_+	ncRNA_intronic
CAediting_858736	chr11_125610265_+	ncRNA_intronic
CAediting_858737	chr11_125610291_+	ncRNA_intronic
CAediting_858738	chr11_125610299_+	ncRNA_intronic
CAediting_858739	chr11_125610300_+	ncRNA_intronic
CAediting_858740	chr11_125610303_+	ncRNA_intronic
CAediting_858741	chr11_125610339_+	ncRNA_intronic
CAediting_858742	chr11_125610432_+	ncRNA_intronic
CAediting_858743	chr11_125610434_+	ncRNA_intronic
CAediting_858744	chr11_125610436_+	ncRNA_intronic
CAediting_858745	chr11_125610447_+	ncRNA_intronic
CAediting_858746	chr11_125610448_+	ncRNA_intronic
CAediting_858747	chr11_125610461_+	ncRNA_intronic
CAediting_858748	chr11_125610463_+	ncRNA_intronic
CAediting_858749	chr11_125610464_+	ncRNA_intronic
CAediting_858750	chr11_125610477_+	ncRNA_intronic
CAediting_858751	chr11_125610494_+	ncRNA_intronic
CAediting_858752	chr11_125610499_+	ncRNA_intronic
CAediting_858753	chr11_125610503_+	ncRNA_intronic
CAediting_858754	chr11_125610504_+	ncRNA_intronic
CAediting_858755	chr11_125610509_+	ncRNA_intronic
CAediting_858756	chr11_125610512_+	ncRNA_intronic
CAediting_858757	chr11_125610513_+	ncRNA_intronic
CAediting_858758	chr11_125610533_+	ncRNA_intronic
CAediting_858759	chr11_125610537_+	ncRNA_intronic
CAediting_858760	chr11_125610583_+	ncRNA_intronic
CAediting_858761	chr11_125610588_+	ncRNA_intronic
CAediting_858762	chr11_125610590_+	ncRNA_intronic
CAediting_858763	chr11_125610596_+	ncRNA_intronic
CAediting_858764	chr11_125610597_+	ncRNA_intronic
CAediting_858765	chr11_125610605_+	ncRNA_intronic
CAediting_858766	chr11_125610612_+	ncRNA_intronic
CAediting_858767	chr11_125610613_+	ncRNA_intronic
CAediting_858768	chr11_125610619_+	ncRNA_intronic
CAediting_858769	chr11_125610642_+	ncRNA_intronic
CAediting_858770	chr11_125610650_+	ncRNA_intronic
CAediting_858771	chr11_125610651_+	ncRNA_intronic
CAediting_858772	chr11_125610653_+	ncRNA_intronic
CAediting_858773	chr11_125610665_+	ncRNA_intronic
CAediting_858774	chr11_125610668_+	ncRNA_intronic
CAediting_858775	chr11_125610670_+	ncRNA_intronic
CAediting_858776	chr11_125610699_+	ncRNA_intronic
CAediting_858777	chr11_125610779_+	ncRNA_exonic
CAediting_858778	chr11_125610783_+	ncRNA_exonic
CAediting_858779	chr11_125610786_+	ncRNA_exonic
CAediting_858780	chr11_125610789_+	ncRNA_exonic
CAediting_858781	chr11_125610802_+	ncRNA_exonic
CAediting_858782	chr11_125610809_+	ncRNA_exonic
CAediting_858783	chr11_125610815_+	ncRNA_exonic
CAediting_858784	chr11_125610821_+	ncRNA_exonic
CAediting_858785	chr11_125610825_+	ncRNA_exonic
CAediting_858786	chr11_125610832_+	ncRNA_exonic
CAediting_858787	chr11_125610838_+	ncRNA_exonic
CAediting_858788	chr11_125610844_+	ncRNA_exonic
CAediting_858789	chr11_125610845_+	ncRNA_exonic
CAediting_858790	chr11_125610851_+	ncRNA_exonic
CAediting_858791	chr11_125610856_+	ncRNA_exonic
CAediting_858792	chr11_125610893_+	ncRNA_exonic
CAediting_858793	chr11_125612110_+	ncRNA_intronic
CAediting_858794	chr11_125615578_+	ncRNA_intronic
CAediting_858795	chr11_125615592_+	ncRNA_intronic
CAediting_858796	chr11_125615635_+	ncRNA_intronic
CAediting_858797	chr11_125615639_+	ncRNA_intronic
CAediting_858798	chr11_125615641_+	ncRNA_intronic
CAediting_858799	chr11_125615654_+	ncRNA_intronic
CAediting_858800	chr11_125616195_+	ncRNA_intronic
CAediting_858801	chr11_125616229_+	ncRNA_intronic
CAediting_858802	chr11_125616233_+	ncRNA_intronic
CAediting_858803	chr11_125616236_+	ncRNA_intronic
CAediting_858804	chr11_125616701_+	ncRNA_intronic
CAediting_858805	chr11_125621857_+	ncRNA_intronic
CAediting_858806	chr11_125621888_+	ncRNA_intronic
CAediting_858807	chr11_125621892_+	ncRNA_intronic
CAediting_858808	chr11_125621950_+	ncRNA_intronic
CAediting_858809	chr11_125621974_+	ncRNA_intronic
CAediting_858810	chr11_125621980_+	ncRNA_intronic
CAediting_858811	chr11_125621981_+	ncRNA_intronic
CAediting_858812	chr11_125622606_+	ncRNA_intronic
CAediting_858813	chr11_125622612_+	ncRNA_intronic
CAediting_858814	chr11_125622628_+	ncRNA_intronic
CAediting_858815	chr11_125622634_+	ncRNA_intronic
CAediting_858816	chr11_125622655_+	ncRNA_intronic
CAediting_858817	chr11_125622674_+	ncRNA_intronic
CAediting_858818	chr11_125622683_+	ncRNA_intronic
CAediting_858819	chr11_125622912_+	ncRNA_intronic
CAediting_858820	chr11_125624541_+	ncRNA_intronic
CAediting_858821	chr11_125624783_+	ncRNA_intronic
CAediting_858822	chr11_125624808_+	ncRNA_intronic
CAediting_858823	chr11_125624809_+	ncRNA_intronic
CAediting_858824	chr11_125624812_+	ncRNA_intronic
CAediting_858825	chr11_125624816_+	ncRNA_intronic
CAediting_858826	chr11_125624822_+	ncRNA_intronic
CAediting_858827	chr11_125624962_+	ncRNA_exonic
CAediting_858828	chr11_125624964_+	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_858720	chr11_125598091_+	SINE	Alu	AluSg
CAediting_858721	chr11_125598101_+	SINE	Alu	AluSg
CAediting_858722	chr11_125598106_+	SINE	Alu	AluSg
CAediting_858723	chr11_125598118_+	SINE	Alu	AluSg
CAediting_858724	chr11_125598132_+	SINE	Alu	AluSg
CAediting_858725	chr11_125598133_+	SINE	Alu	AluSg
CAediting_858726	chr11_125601544_+	SINE	Alu	AluSq2
CAediting_858727	chr11_125610086_+	SINE	Alu	AluJb
CAediting_858728	chr11_125610162_+	SINE	Alu	AluJb
CAediting_858729	chr11_125610163_+	SINE	Alu	AluJb
CAediting_858730	chr11_125610167_+	SINE	Alu	AluJb
CAediting_858731	chr11_125610192_+	SINE	Alu	AluJb
CAediting_858732	chr11_125610199_+	SINE	Alu	AluJb
CAediting_858733	chr11_125610202_+	SINE	Alu	AluJb
CAediting_858734	chr11_125610204_+	SINE	Alu	AluJb
CAediting_858735	chr11_125610215_+	SINE	Alu	AluJb
CAediting_858736	chr11_125610265_+	SINE	Alu	AluJb
CAediting_858737	chr11_125610291_+	SINE	Alu	AluJb
CAediting_858738	chr11_125610299_+	SINE	Alu	AluJb
CAediting_858739	chr11_125610300_+	SINE	Alu	AluJb
CAediting_858740	chr11_125610303_+	SINE	Alu	AluJb
CAediting_858741	chr11_125610339_+	SINE	Alu	AluJb
CAediting_858745	chr11_125610447_+	SINE	Alu	AluJr
CAediting_858746	chr11_125610448_+	SINE	Alu	AluJr
CAediting_858747	chr11_125610461_+	SINE	Alu	AluJr
CAediting_858748	chr11_125610463_+	SINE	Alu	AluJr
CAediting_858749	chr11_125610464_+	SINE	Alu	AluJr
CAediting_858750	chr11_125610477_+	SINE	Alu	AluJr
CAediting_858751	chr11_125610494_+	SINE	Alu	AluJr
CAediting_858752	chr11_125610499_+	SINE	Alu	AluJr
CAediting_858753	chr11_125610503_+	SINE	Alu	AluJr
CAediting_858754	chr11_125610504_+	SINE	Alu	AluJr
CAediting_858755	chr11_125610509_+	SINE	Alu	AluJr
CAediting_858756	chr11_125610512_+	SINE	Alu	AluJr
CAediting_858757	chr11_125610513_+	SINE	Alu	AluJr
CAediting_858758	chr11_125610533_+	SINE	Alu	AluJr
CAediting_858759	chr11_125610537_+	SINE	Alu	AluJr
CAediting_858760	chr11_125610583_+	SINE	Alu	AluJr
CAediting_858761	chr11_125610588_+	SINE	Alu	AluJr
CAediting_858762	chr11_125610590_+	SINE	Alu	AluJr
CAediting_858763	chr11_125610596_+	SINE	Alu	AluJr
CAediting_858764	chr11_125610597_+	SINE	Alu	AluJr
CAediting_858765	chr11_125610605_+	SINE	Alu	AluJr
CAediting_858766	chr11_125610612_+	SINE	Alu	AluJr
CAediting_858767	chr11_125610613_+	SINE	Alu	AluJr
CAediting_858768	chr11_125610619_+	SINE	Alu	AluJr
CAediting_858769	chr11_125610642_+	SINE	Alu	AluJr
CAediting_858770	chr11_125610650_+	SINE	Alu	AluJr
CAediting_858771	chr11_125610651_+	SINE	Alu	AluJr
CAediting_858772	chr11_125610653_+	SINE	Alu	AluJr
CAediting_858773	chr11_125610665_+	SINE	Alu	AluJr
CAediting_858774	chr11_125610668_+	SINE	Alu	AluJr
CAediting_858775	chr11_125610670_+	SINE	Alu	AluJr
CAediting_858776	chr11_125610699_+	SINE	Alu	AluJr
CAediting_858777	chr11_125610779_+	SINE	Alu	AluJr
CAediting_858778	chr11_125610783_+	SINE	Alu	AluJr
CAediting_858779	chr11_125610786_+	SINE	Alu	AluJr
CAediting_858780	chr11_125610789_+	SINE	Alu	AluJr
CAediting_858781	chr11_125610802_+	SINE	Alu	AluJr
CAediting_858782	chr11_125610809_+	SINE	Alu	AluJr
CAediting_858783	chr11_125610815_+	SINE	Alu	AluJr
CAediting_858784	chr11_125610821_+	SINE	Alu	AluJr
CAediting_858785	chr11_125610825_+	SINE	Alu	AluJr
CAediting_858786	chr11_125610832_+	SINE	Alu	AluJr
CAediting_858787	chr11_125610838_+	SINE	Alu	AluJr
CAediting_858788	chr11_125610844_+	SINE	Alu	AluJr
CAediting_858789	chr11_125610845_+	SINE	Alu	AluJr
CAediting_858790	chr11_125610851_+	SINE	Alu	AluJr
CAediting_858791	chr11_125610856_+	SINE	Alu	AluJr
CAediting_858793	chr11_125612110_+	SINE	Alu	AluSp
CAediting_858794	chr11_125615578_+	DNA	TcMar-Tigger	MER2
CAediting_858795	chr11_125615592_+	DNA	TcMar-Tigger	MER2
CAediting_858796	chr11_125615635_+	DNA	TcMar-Tigger	MER2
CAediting_858797	chr11_125615639_+	DNA	TcMar-Tigger	MER2
CAediting_858798	chr11_125615641_+	DNA	TcMar-Tigger	MER2
CAediting_858799	chr11_125615654_+	DNA	TcMar-Tigger	MER2
CAediting_858800	chr11_125616195_+	DNA	TcMar-Tigger	MER2
CAediting_858801	chr11_125616229_+	DNA	TcMar-Tigger	MER2
CAediting_858802	chr11_125616233_+	DNA	TcMar-Tigger	MER2
CAediting_858803	chr11_125616236_+	DNA	TcMar-Tigger	MER2
CAediting_858804	chr11_125616701_+	SINE	Alu	AluJb
CAediting_858805	chr11_125621857_+	SINE	Alu	AluJb
CAediting_858806	chr11_125621888_+	SINE	Alu	AluJb
CAediting_858807	chr11_125621892_+	SINE	Alu	AluJb
CAediting_858808	chr11_125621950_+	SINE	Alu	AluJb
CAediting_858809	chr11_125621974_+	SINE	Alu	AluJb
CAediting_858810	chr11_125621980_+	SINE	Alu	AluJb
CAediting_858811	chr11_125621981_+	SINE	Alu	AluJb
CAediting_858812	chr11_125622606_+	SINE	Alu	AluJb
CAediting_858813	chr11_125622612_+	SINE	Alu	AluJb
CAediting_858814	chr11_125622628_+	SINE	Alu	AluJb
CAediting_858815	chr11_125622634_+	SINE	Alu	AluJb
CAediting_858816	chr11_125622655_+	SINE	Alu	AluJb
CAediting_858817	chr11_125622674_+	SINE	Alu	AluJb
CAediting_858818	chr11_125622683_+	SINE	Alu	AluJb
CAediting_858819	chr11_125622912_+	SINE	Alu	AluSz6
CAediting_858820	chr11_125624541_+	SINE	Alu	AluSx1
CAediting_858821	chr11_125624783_+	SINE	Alu	AluJr4
CAediting_858822	chr11_125624808_+	SINE	Alu	AluJr4
CAediting_858823	chr11_125624809_+	SINE	Alu	AluJr4
CAediting_858824	chr11_125624812_+	SINE	Alu	AluJr4
CAediting_858825	chr11_125624816_+	SINE	Alu	AluJr4
CAediting_858826	chr11_125624822_+	SINE	Alu	AluJr4
CAediting_858827	chr11_125624962_+	SINE	Alu	AluJr4
CAediting_858828	chr11_125624964_+	SINE	Alu	AluJr4

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RNA A-to-I editing events in the alternative splicing sites for STT3A

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000134910.11.STT3A.

Correlation between RNA A-to-I editing and PSI for ENSG00000134910.11.STT3A.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for STT3A

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for STT3A

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for STT3A

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_858806	chr11_125621888_+	ENSG00000134910.11	ENST00000392708	hsa-miR-3190-5p	125621886	125621892	7mer-m8	125621874	125621893	143.00	-16.24
CAediting_858806	chr11_125621888_+	ENSG00000134910.11	ENST00000392708	hsa-miR-548s	125621885	125621891	7mer-m8	125621870	125621892	140.00	-12.15
CAediting_858807	chr11_125621892_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125621888	125621895	8mer-1a	125621873	125621895	146.00	-18.46
CAediting_858807	chr11_125621892_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125621888	125621895	8mer-1a	125621873	125621895	146.00	-18.46
CAediting_858807	chr11_125621892_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125621888	125621895	8mer-1a	125621873	125621895	146.00	-18.46
CAediting_858807	chr11_125621892_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125621888	125621895	8mer-1a	125621873	125621895	146.00	-18.46
CAediting_858807	chr11_125621892_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125621888	125621895	8mer-1a	125621873	125621895	146.00	-18.46
CAediting_858809	chr11_125621974_+	ENSG00000134910.11	ENST00000392708	hsa-miR-4418	125621971	125621977	7mer-m8	125621962	125621978	154.00	-25.27
CAediting_858809	chr11_125621974_+	ENSG00000134910.11	ENST00000392708	hsa-miR-509-3-5p	125621971	125621977	7mer-m8	125621957	125621978	147.00	-18.76
CAediting_858809	chr11_125621974_+	ENSG00000134910.11	ENST00000392708	hsa-miR-509-5p	125621971	125621977	7mer-m8	125621958	125621978	142.00	-18.06
CAediting_858809	chr11_125621974_+	ENSG00000134910.11	ENST00000392708	hsa-miR-509-5p	125621971	125621977	7mer-m8	125621958	125621978	142.00	-18.06
CAediting_858809	chr11_125621974_+	ENSG00000134910.11	ENST00000392708	hsa-miR-7156-3p	125621969	125621975	7mer-m8	125621954	125621976	142.00	-20.34
CAediting_858810	chr11_125621980_+	ENSG00000134910.11	ENST00000392708	hsa-miR-455-3p	125621977	125621983	7mer-m8	125621962	125621984	149.00	-18.68
CAediting_858810	chr11_125621980_+	ENSG00000134910.11	ENST00000392708	hsa-miR-6509-3p	125621974	125621980	7mer-m8	125621957	125621981	152.00	-17.53
CAediting_858812	chr11_125622606_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125622602	125622608	7mer-m8	125622587	125622609	141.00	-21.20
CAediting_858812	chr11_125622606_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125622602	125622608	7mer-m8	125622587	125622609	141.00	-21.20
CAediting_858812	chr11_125622606_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125622602	125622608	7mer-m8	125622587	125622609	141.00	-21.20
CAediting_858812	chr11_125622606_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125622602	125622608	7mer-m8	125622587	125622609	141.00	-21.20
CAediting_858812	chr11_125622606_+	ENSG00000134910.11	ENST00000392708	hsa-miR-941	125622602	125622608	7mer-m8	125622587	125622609	141.00	-21.20
CAediting_858814	chr11_125622628_+	ENSG00000134910.11	ENST00000392708	hsa-miR-513a-5p	125622622	125622628	7mer-m8	125622612	125622629	152.00	-17.32
CAediting_858814	chr11_125622628_+	ENSG00000134910.11	ENST00000392708	hsa-miR-513a-5p	125622622	125622628	7mer-m8	125622612	125622629	152.00	-17.32
CAediting_858814	chr11_125622628_+	ENSG00000134910.11	ENST00000392708	hsa-miR-638	125622627	125622633	7mer-1a	125622607	125622633	154.00	-31.53
CAediting_858815	chr11_125622634_+	ENSG00000134910.11	ENST00000392708	hsa-miR-371a-3p	125622632	125622638	7mer-m8	125622617	125622639	144.00	-15.05
CAediting_858818	chr11_125622683_+	ENSG00000134910.11	ENST00000392708	hsa-miR-1200	125622679	125622684	6mer	125622666	125622685	144.00	-19.84
CAediting_858818	chr11_125622683_+	ENSG00000134910.11	ENST00000392708	hsa-miR-12113	125622676	125622682	7mer-m8	125622665	125622683	152.00	-21.73
CAediting_858818	chr11_125622683_+	ENSG00000134910.11	ENST00000392708	hsa-miR-4539	125622676	125622682	7mer-m8	125622659	125622683	159.00	-23.29
CAediting_858819	chr11_125622912_+	ENSG00000134910.11	ENST00000392708	hsa-miR-2467-3p	125622907	125622912	6mer	125622892	125622913	149.00	-29.37
CAediting_858819	chr11_125622912_+	ENSG00000134910.11	ENST00000392708	hsa-miR-374b-3p	125622909	125622916	8mer-1a	125622893	125622916	145.00	-9.63

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_858814	chr11_125622628_+	ENSG00000134910.11	ENST00000392708	hsa-miR-10399-5p	125622623	125622629	7mer-m8	125622609	125622630	144	-10.52
CAediting_858817	chr11_125622674_+	ENSG00000134910.11	ENST00000392708	hsa-miR-10400-3p	125622667	125622673	7mer-m8	125622653	125622674	140	-22.2
CAediting_858809	chr11_125621974_+	ENSG00000134910.11	ENST00000392708	hsa-miR-1183	125621971	125621977	7mer-m8	125621952	125621978	140	-18.25
CAediting_858808	chr11_125621950_+	ENSG00000134910.11	ENST00000392708	hsa-miR-1245a	125621945	125621951	7mer-m8	125621932	125621952	141	-15.11
CAediting_858817	chr11_125622674_+	ENSG00000134910.11	ENST00000392708	hsa-miR-1343-3p	125622670	125622676	7mer-m8	125622656	125622677	140	-24.19
CAediting_858809	chr11_125621974_+	ENSG00000134910.11	ENST00000392708	hsa-miR-20b-3p	125621971	125621976	6mer	125621957	125621977	142	-24.51
CAediting_858813	chr11_125622612_+	ENSG00000134910.11	ENST00000392708	hsa-miR-217-5p	125622608	125622613	6mer	125622592	125622614	145	-20.38
CAediting_858809	chr11_125621974_+	ENSG00000134910.11	ENST00000392708	hsa-miR-3137	125621970	125621976	7mer-m8	125621954	125621977	150	-22.75
CAediting_858812	chr11_125622606_+	ENSG00000134910.11	ENST00000392708	hsa-miR-3176	125622600	125622606	7mer-m8	125622589	125622607	147	-18.74
CAediting_858816	chr11_125622655_+	ENSG00000134910.11	ENST00000392708	hsa-miR-3977	125622648	125622654	7mer-m8	125622633	125622655	146	-11.01
CAediting_858813	chr11_125622612_+	ENSG00000134910.11	ENST00000392708	hsa-miR-4252	125622610	125622616	7mer-m8	125622599	125622617	146	-17.81
CAediting_858817	chr11_125622674_+	ENSG00000134910.11	ENST00000392708	hsa-miR-4674	125622667	125622673	7mer-m8	125622652	125622674	149	-28.99
CAediting_858806	chr11_125621888_+	ENSG00000134910.11	ENST00000392708	hsa-miR-4735-5p	125621882	125621888	7mer-m8	125621868	125621889	140	-6.66
CAediting_858806	chr11_125621888_+	ENSG00000134910.11	ENST00000392708	hsa-miR-4794	125621886	125621892	7mer-m8	125621872	125621893	140	-12.23
CAediting_858807	chr11_125621892_+	ENSG00000134910.11	ENST00000392708	hsa-miR-4794	125621886	125621892	7mer-m8	125621872	125621893	140	-12.23
CAediting_858815	chr11_125622634_+	ENSG00000134910.11	ENST00000392708	hsa-miR-5089-5p	125622627	125622633	7mer-m8	125622615	125622634	146	-13.24
CAediting_858815	chr11_125622634_+	ENSG00000134910.11	ENST00000392708	hsa-miR-512-3p	125622632	125622638	7mer-m8	125622618	125622639	149	-15
CAediting_858815	chr11_125622634_+	ENSG00000134910.11	ENST00000392708	hsa-miR-512-3p	125622632	125622638	7mer-m8	125622618	125622639	149	-15
CAediting_858815	chr11_125622634_+	ENSG00000134910.11	ENST00000392708	hsa-miR-6506-5p	125622628	125622634	7mer-m8	125622613	125622635	144	-16.21
CAediting_858806	chr11_125621888_+	ENSG00000134910.11	ENST00000392708	hsa-miR-664a-5p	125621886	125621892	7mer-m8	125621870	125621893	141	-12.64
CAediting_858807	chr11_125621892_+	ENSG00000134910.11	ENST00000392708	hsa-miR-664a-5p	125621886	125621892	7mer-m8	125621870	125621893	141	-12.64
CAediting_858812	chr11_125622606_+	ENSG00000134910.11	ENST00000392708	hsa-miR-6765-3p	125622603	125622609	7mer-m8	125622589	125622610	147	-18.33
CAediting_858817	chr11_125622674_+	ENSG00000134910.11	ENST00000392708	hsa-miR-6783-3p	125622670	125622676	7mer-m8	125622656	125622677	151	-23.86
CAediting_858812	chr11_125622606_+	ENSG00000134910.11	ENST00000392708	hsa-miR-6804-3p	125622604	125622611	8mer-1a	125622589	125622611	146	-15.92
CAediting_858819	chr11_125622912_+	ENSG00000134910.11	ENST00000392708	hsa-miR-6832-5p	125622906	125622912	7mer-m8	125622893	125622913	146	-15.8
CAediting_858814	chr11_125622628_+	ENSG00000134910.11	ENST00000392708	hsa-miR-7151-3p	125622621	125622628	8mer-1a	125622612	125622628	146	-17.62
CAediting_858808	chr11_125621950_+	ENSG00000134910.11	ENST00000392708	hsa-miR-8079	125621945	125621951	7mer-m8	125621933	125621952	149	-14.52
CAediting_858817	chr11_125622674_+	ENSG00000134910.11	ENST00000392708	hsa-miR-939-3p	125622669	125622676	8mer-1a	125622654	125622676	148	-20.56

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000134910.11	ENST00000392708	hsa-miR-624-3p	125622948	125622955	8mer-1a	125622937	125622955	148	-16.61
CAediting_393	chr1_1167164_+	ENSG00000134910.11	ENST00000392708	hsa-miR-200b-3p	125621495	125621502	8mer-1a	125621481	125621502	140	-12.85
CAediting_688081	chr9_63819627_+	ENSG00000134910.11	ENST00000392708	hsa-miR-4477b	125621161	125621168	8mer-1a	125621147	125621168	152	-10.77
CAediting_1229415	chr17_67471547_+	ENSG00000134910.11	ENST00000392708	hsa-miR-548aa	125621019	125621026	8mer-1a	125621000	125621026	158	-10.32
CAediting_228905	chr2_188297554_+	ENSG00000134910.11	ENST00000392708	hsa-miR-561-3p	125622898	125622904	7mer-m8	125622884	125622905	142	-15.56
CAediting_228905	chr2_188297554_+	ENSG00000134910.11	ENST00000392708	hsa-miR-561-3p	125621486	125621492	7mer-m8	125621474	125621493	142	-12.46
CAediting_228905	chr2_188297554_+	ENSG00000134910.11	ENST00000392708	hsa-miR-561-3p	125621627	125621633	7mer-m8	125621613	125621634	140	-7.47
CAediting_396018	chr5_1062918_-	ENSG00000134910.11	ENST00000392708	hsa-miR-4635	125622314	125622321	8mer-1a	125622301	125622321	159	-18.88
CAediting_524911	chr7_5495852_-	ENSG00000134910.11	ENST00000392708	hsa-miR-589-3p	125622487	125622494	8mer-1a	125622472	125622494	148	-17.72

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_573001	chr7_92204086_-	ENSG00000134910.11	ENST00000392708	hsa-miR-1285-5p	125622303	125622309	7mer-m8	125622288	125622310	146	-16.65
CAediting_1368054	chr19_46709310_-	ENSG00000134910.11	ENST00000392708	hsa-miR-320e	125621539	125621545	7mer-1a	125621528	125621545	144	-12.04
CAediting_980496	chr14_31014685_-	ENSG00000134910.11	ENST00000392708	hsa-miR-624-3p	125621141	125621147	7mer-m8	125621128	125621148	148	-14.15
CAediting_1351755	chr19_40282625_-	ENSG00000134910.11	ENST00000392708	hsa-miR-641	125622728	125622734	7mer-m8	125622711	125622735	145	-11.45

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for STT3A

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for STT3A

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for STT3A

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ESCA	clinical_stage	CAediting_858775	chr11_125610670_+	0.0185667220607235	-0.441858250336877
KIRC	pathologic_stage	CAediting_858775	chr11_125610670_+	0.031148483521461	0.278558417529484
STAD	pathologic_stage	CAediting_858775	chr11_125610670_+	0.0275793094647963	0.178153298804069

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Relation with survival for STT3A

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
STAD	CAediting_858753	chr11_125610503_+	0.0308365237157314	0.0364461	119.093
OV	CAediting_858775	chr11_125610670_+	0.0268470544236427	0.00667831	6.93071

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RelatedDrugs for STT3A

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for STT3A

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
STT3A	C0424605	Developmental delay (disorder)	1	GENOMICS_ENGLAND
STT3A	C0557874	Global developmental delay	1	GENOMICS_ENGLAND
STT3A	C3714756	Intellectual Disability	1	GENOMICS_ENGLAND
STT3A	C3810062	Congenital disorder of glycosylation type 1w	1	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene