Home

Download

Statistics

Examples

Help

Contact

Editing gene: IRS1 (CAeditome ID:3667)

Gene summary for IRS1

Gene summary

Gene information	Gene symbol	IRS1
	Gene ID	3667
	Gene name	insulin receptor substrate 1
	Synonyms	HIRS-1
	Cytomap	2q36.3
	Type of gene	protein-coding
	Description	insulin receptor substrate 1
	Modification date	20210531
	UniProtAcc	P35568
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
IRS1	GO:0030159	Insulin receptor substrate 1	7493946
IRS1	GO:0008286	Insulin receptor substrate 1	16516141
IRS1	GO:0008286	Insulin receptor substrate 1	23401856
IRS1	GO:0014065	Insulin receptor substrate 1	7782332
IRS1	GO:0032868	Insulin receptor substrate 1	16516141
IRS1	GO:0046326	Insulin receptor substrate 1	7493946
IRS1	GO:0046628	Insulin receptor substrate 1	7493946
IRS1	GO:0046676	Insulin receptor substrate 1	15572028
IRS1	GO:0005654	Insulin receptor substrate 1	0000052
IRS1	GO:0005829	Insulin receptor substrate 1	0000052
IRS1	GO:0005886	Insulin receptor substrate 1	0000052
IRS1	GO:0005901	Insulin receptor substrate 1	15182363

Top

RNA A-to-I events for IRS1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000169047.5

RNA A-to-I editing events in Cancer.

CAediting_246070(226746872, -), CAediting_246071(226746875, -), CAediting_246072(226751356, -), CAediting_246073(226751448, -), CAediting_246074(226751556, -), CAediting_246075(226754062, -), CAediting_246076(226757504, -), CAediting_246077(226760048, -), CAediting_246078(226760068, -), CAediting_246079(226760134, -), CAediting_246080(226764341, -), CAediting_246081(226764540, -), CAediting_246082(226766249, -), CAediting_246083(226766253, -), CAediting_246084(226766272, -), CAediting_246085(226766279, -), CAediting_246086(226766280, -), CAediting_246087(226766288, -), CAediting_246088(226766292, -), CAediting_246089(226766301, -), CAediting_246090(226766302, -), CAediting_246091(226766310, -), CAediting_246092(226766312, -), CAediting_246093(226766323, -), CAediting_246094(226766328, -), CAediting_246095(226766331, -), CAediting_246096(226766332, -), CAediting_246097(226766334, -), CAediting_246098(226766337, -), CAediting_246099(226766341, -), CAediting_246100(226766342, -), CAediting_246101(226766343, -), CAediting_246102(226766357, -), CAediting_246103(226766359, -), CAediting_246104(226766360, -), CAediting_246105(226766365, -), CAediting_246106(226766377, -), CAediting_246107(226766380, -), CAediting_246108(226766382, -), CAediting_246109(226766383, -), CAediting_246110(226766391, -), CAediting_246111(226766396, -), CAediting_246112(226766401, -), CAediting_246113(226766409, -), CAediting_246114(226766410, -), CAediting_246115(226766415, -), CAediting_246116(226766416, -), CAediting_246117(226766420, -), CAediting_246118(226766444, -), CAediting_246119(226782844, -), CAediting_246120(226782853, -), CAediting_246121(226784449, -), CAediting_246122(226784450, -), CAediting_246123(226784462, -), CAediting_246124(226784490, -), CAediting_246125(226784512, -), CAediting_246126(226784514, -), CAediting_246127(226784519, -), CAediting_246128(226784520, -), CAediting_246129(226784528, -), CAediting_246130(226784544, -), CAediting_246131(226784551, -), CAediting_246132(226784560, -), CAediting_246133(226784561, -), CAediting_246134(226784571, -), CAediting_246135(226784587, -), CAediting_246136(226784590, -), CAediting_246137(226784591, -), CAediting_246138(226784593, -), CAediting_246139(226784600, -), CAediting_246140(226784601, -), CAediting_246141(226784602, -), CAediting_246142(226784605, -), CAediting_246143(226784616, -), CAediting_246144(226784617, -), CAediting_246145(226784618, -), CAediting_246146(226784650, -), CAediting_246147(226784655, -), CAediting_246148(226784679, -), CAediting_246149(226784687, -), CAediting_246150(226784695, -), CAediting_246151(226784696, -), CAediting_246152(226784714, -), CAediting_246153(226785337, -), CAediting_246154(226785346, -), CAediting_246155(226785358, -), CAediting_246156(226785359, -), CAediting_246157(226785385, -), CAediting_246158(226785423, -), CAediting_246159(226785435, -), CAediting_246160(226785437, -), CAediting_246161(226785454, -), CAediting_246162(226785481, -), CAediting_246163(226785491, -), CAediting_246164(226785509, -), CAediting_246165(226785516, -), CAediting_246166(226785520, -), CAediting_246167(226785589, -), CAediting_246168(226785599, -), CAediting_246169(226785601, -),

Top

RNA editing positional annotations for IRS1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_246070	chr2_226746872_-	intronic
CAediting_246071	chr2_226746875_-	intronic
CAediting_246072	chr2_226751356_-	intronic
CAediting_246073	chr2_226751448_-	intronic
CAediting_246074	chr2_226751556_-	intronic
CAediting_246075	chr2_226754062_-	intronic
CAediting_246076	chr2_226757504_-	intronic
CAediting_246077	chr2_226760048_-	intronic
CAediting_246078	chr2_226760068_-	intronic
CAediting_246079	chr2_226760134_-	intronic
CAediting_246080	chr2_226764341_-	intronic
CAediting_246081	chr2_226764540_-	intronic
CAediting_246082	chr2_226766249_-	intronic
CAediting_246083	chr2_226766253_-	intronic
CAediting_246084	chr2_226766272_-	intronic
CAediting_246085	chr2_226766279_-	intronic
CAediting_246086	chr2_226766280_-	intronic
CAediting_246087	chr2_226766288_-	intronic
CAediting_246088	chr2_226766292_-	intronic
CAediting_246089	chr2_226766301_-	intronic
CAediting_246090	chr2_226766302_-	intronic
CAediting_246091	chr2_226766310_-	intronic
CAediting_246092	chr2_226766312_-	intronic
CAediting_246093	chr2_226766323_-	intronic
CAediting_246094	chr2_226766328_-	intronic
CAediting_246095	chr2_226766331_-	intronic
CAediting_246096	chr2_226766332_-	intronic
CAediting_246097	chr2_226766334_-	intronic
CAediting_246098	chr2_226766337_-	intronic
CAediting_246099	chr2_226766341_-	intronic
CAediting_246100	chr2_226766342_-	intronic
CAediting_246101	chr2_226766343_-	intronic
CAediting_246102	chr2_226766357_-	intronic
CAediting_246103	chr2_226766359_-	intronic
CAediting_246104	chr2_226766360_-	intronic
CAediting_246105	chr2_226766365_-	intronic
CAediting_246106	chr2_226766377_-	intronic
CAediting_246107	chr2_226766380_-	intronic
CAediting_246108	chr2_226766382_-	intronic
CAediting_246109	chr2_226766383_-	intronic
CAediting_246110	chr2_226766391_-	intronic
CAediting_246111	chr2_226766396_-	intronic
CAediting_246112	chr2_226766401_-	intronic
CAediting_246113	chr2_226766409_-	intronic
CAediting_246114	chr2_226766410_-	intronic
CAediting_246115	chr2_226766415_-	intronic
CAediting_246116	chr2_226766416_-	intronic
CAediting_246117	chr2_226766420_-	intronic
CAediting_246118	chr2_226766444_-	intronic
CAediting_246119	chr2_226782844_-	intronic
CAediting_246120	chr2_226782853_-	intronic
CAediting_246121	chr2_226784449_-	intronic
CAediting_246122	chr2_226784450_-	intronic
CAediting_246123	chr2_226784462_-	intronic
CAediting_246124	chr2_226784490_-	intronic
CAediting_246125	chr2_226784512_-	intronic
CAediting_246126	chr2_226784514_-	intronic
CAediting_246127	chr2_226784519_-	intronic
CAediting_246128	chr2_226784520_-	intronic
CAediting_246129	chr2_226784528_-	intronic
CAediting_246130	chr2_226784544_-	intronic
CAediting_246131	chr2_226784551_-	intronic
CAediting_246132	chr2_226784560_-	intronic
CAediting_246133	chr2_226784561_-	intronic
CAediting_246134	chr2_226784571_-	intronic
CAediting_246135	chr2_226784587_-	intronic
CAediting_246136	chr2_226784590_-	intronic
CAediting_246137	chr2_226784591_-	intronic
CAediting_246138	chr2_226784593_-	intronic
CAediting_246139	chr2_226784600_-	intronic
CAediting_246140	chr2_226784601_-	intronic
CAediting_246141	chr2_226784602_-	intronic
CAediting_246142	chr2_226784605_-	intronic
CAediting_246143	chr2_226784616_-	intronic
CAediting_246144	chr2_226784617_-	intronic
CAediting_246145	chr2_226784618_-	intronic
CAediting_246146	chr2_226784650_-	intronic
CAediting_246147	chr2_226784655_-	intronic
CAediting_246148	chr2_226784679_-	intronic
CAediting_246149	chr2_226784687_-	intronic
CAediting_246150	chr2_226784695_-	intronic
CAediting_246151	chr2_226784696_-	intronic
CAediting_246152	chr2_226784714_-	intronic
CAediting_246153	chr2_226785337_-	intronic
CAediting_246154	chr2_226785346_-	intronic
CAediting_246155	chr2_226785358_-	intronic
CAediting_246156	chr2_226785359_-	intronic
CAediting_246157	chr2_226785385_-	intronic
CAediting_246158	chr2_226785423_-	intronic
CAediting_246159	chr2_226785435_-	intronic
CAediting_246160	chr2_226785437_-	intronic
CAediting_246161	chr2_226785454_-	intronic
CAediting_246162	chr2_226785481_-	intronic
CAediting_246163	chr2_226785491_-	intronic
CAediting_246164	chr2_226785509_-	intronic
CAediting_246165	chr2_226785516_-	intronic
CAediting_246166	chr2_226785520_-	intronic
CAediting_246167	chr2_226785589_-	intronic
CAediting_246168	chr2_226785599_-	intronic
CAediting_246169	chr2_226785601_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_246070	chr2_226746872_-	SINE	Alu	AluSx
CAediting_246071	chr2_226746875_-	SINE	Alu	AluSx
CAediting_246072	chr2_226751356_-	SINE	Alu	AluY
CAediting_246073	chr2_226751448_-	SINE	Alu	AluY
CAediting_246074	chr2_226751556_-	SINE	Alu	AluY
CAediting_246075	chr2_226754062_-	SINE	Alu	AluJb
CAediting_246076	chr2_226757504_-	SINE	Alu	AluSx
CAediting_246077	chr2_226760048_-	SINE	Alu	AluJb
CAediting_246078	chr2_226760068_-	SINE	Alu	AluJb
CAediting_246079	chr2_226760134_-	SINE	Alu	AluJb
CAediting_246080	chr2_226764341_-	SINE	Alu	AluJr
CAediting_246081	chr2_226764540_-	SINE	Alu	AluJr
CAediting_246082	chr2_226766249_-	SINE	Alu	AluSz6
CAediting_246083	chr2_226766253_-	SINE	Alu	AluSz6
CAediting_246084	chr2_226766272_-	SINE	Alu	AluSz6
CAediting_246085	chr2_226766279_-	SINE	Alu	AluSz6
CAediting_246086	chr2_226766280_-	SINE	Alu	AluSz6
CAediting_246087	chr2_226766288_-	SINE	Alu	AluSz6
CAediting_246088	chr2_226766292_-	SINE	Alu	AluSz6
CAediting_246089	chr2_226766301_-	SINE	Alu	AluSz6
CAediting_246090	chr2_226766302_-	SINE	Alu	AluSz6
CAediting_246091	chr2_226766310_-	SINE	Alu	AluSz6
CAediting_246092	chr2_226766312_-	SINE	Alu	AluSz6
CAediting_246093	chr2_226766323_-	SINE	Alu	AluSz6
CAediting_246094	chr2_226766328_-	SINE	Alu	AluSz6
CAediting_246095	chr2_226766331_-	SINE	Alu	AluSz6
CAediting_246096	chr2_226766332_-	SINE	Alu	AluSz6
CAediting_246097	chr2_226766334_-	SINE	Alu	AluSz6
CAediting_246098	chr2_226766337_-	SINE	Alu	AluSz6
CAediting_246099	chr2_226766341_-	SINE	Alu	AluSz6
CAediting_246100	chr2_226766342_-	SINE	Alu	AluSz6
CAediting_246101	chr2_226766343_-	SINE	Alu	AluSz6
CAediting_246102	chr2_226766357_-	SINE	Alu	AluSz6
CAediting_246103	chr2_226766359_-	SINE	Alu	AluSz6
CAediting_246104	chr2_226766360_-	SINE	Alu	AluSz6
CAediting_246105	chr2_226766365_-	SINE	Alu	AluSz6
CAediting_246106	chr2_226766377_-	SINE	Alu	AluSz6
CAediting_246107	chr2_226766380_-	SINE	Alu	AluSz6
CAediting_246108	chr2_226766382_-	SINE	Alu	AluSz6
CAediting_246109	chr2_226766383_-	SINE	Alu	AluSz6
CAediting_246110	chr2_226766391_-	SINE	Alu	AluSz6
CAediting_246111	chr2_226766396_-	SINE	Alu	AluSz6
CAediting_246112	chr2_226766401_-	SINE	Alu	AluSz6
CAediting_246113	chr2_226766409_-	SINE	Alu	AluSz6
CAediting_246114	chr2_226766410_-	SINE	Alu	AluSz6
CAediting_246115	chr2_226766415_-	SINE	Alu	AluSz6
CAediting_246116	chr2_226766416_-	SINE	Alu	AluSz6
CAediting_246117	chr2_226766420_-	SINE	Alu	AluSz6
CAediting_246118	chr2_226766444_-	SINE	Alu	AluSz6
CAediting_246119	chr2_226782844_-	SINE	Alu	AluSz
CAediting_246120	chr2_226782853_-	SINE	Alu	AluSz
CAediting_246121	chr2_226784449_-	SINE	Alu	AluSq2
CAediting_246122	chr2_226784450_-	SINE	Alu	AluSq2
CAediting_246123	chr2_226784462_-	SINE	Alu	AluSq2
CAediting_246124	chr2_226784490_-	SINE	Alu	AluSq2
CAediting_246125	chr2_226784512_-	SINE	Alu	AluSq2
CAediting_246126	chr2_226784514_-	SINE	Alu	AluSq2
CAediting_246127	chr2_226784519_-	SINE	Alu	AluSq2
CAediting_246128	chr2_226784520_-	SINE	Alu	AluSq2
CAediting_246129	chr2_226784528_-	SINE	Alu	AluSq2
CAediting_246130	chr2_226784544_-	SINE	Alu	AluSq2
CAediting_246131	chr2_226784551_-	SINE	Alu	AluSq2
CAediting_246132	chr2_226784560_-	SINE	Alu	AluSq2
CAediting_246133	chr2_226784561_-	SINE	Alu	AluSq2
CAediting_246134	chr2_226784571_-	SINE	Alu	AluSq2
CAediting_246135	chr2_226784587_-	SINE	Alu	AluSq2
CAediting_246136	chr2_226784590_-	SINE	Alu	AluSq2
CAediting_246137	chr2_226784591_-	SINE	Alu	AluSq2
CAediting_246138	chr2_226784593_-	SINE	Alu	AluSq2
CAediting_246139	chr2_226784600_-	SINE	Alu	AluSq2
CAediting_246140	chr2_226784601_-	SINE	Alu	AluSq2
CAediting_246141	chr2_226784602_-	SINE	Alu	AluSq2
CAediting_246142	chr2_226784605_-	SINE	Alu	AluSq2
CAediting_246143	chr2_226784616_-	SINE	Alu	AluSq2
CAediting_246144	chr2_226784617_-	SINE	Alu	AluSq2
CAediting_246145	chr2_226784618_-	SINE	Alu	AluSq2
CAediting_246146	chr2_226784650_-	SINE	Alu	AluSq2
CAediting_246147	chr2_226784655_-	SINE	Alu	AluSq2
CAediting_246148	chr2_226784679_-	SINE	Alu	AluSq2
CAediting_246149	chr2_226784687_-	SINE	Alu	AluSq2
CAediting_246150	chr2_226784695_-	SINE	Alu	AluSq2
CAediting_246151	chr2_226784696_-	SINE	Alu	AluSq2
CAediting_246152	chr2_226784714_-	SINE	Alu	AluSq2
CAediting_246153	chr2_226785337_-	SINE	Alu	AluSz
CAediting_246154	chr2_226785346_-	SINE	Alu	AluSz
CAediting_246155	chr2_226785358_-	SINE	Alu	AluSz
CAediting_246156	chr2_226785359_-	SINE	Alu	AluSz
CAediting_246157	chr2_226785385_-	SINE	Alu	AluSz
CAediting_246158	chr2_226785423_-	SINE	Alu	AluSz
CAediting_246159	chr2_226785435_-	SINE	Alu	AluSz
CAediting_246160	chr2_226785437_-	SINE	Alu	AluSz
CAediting_246161	chr2_226785454_-	SINE	Alu	AluSz
CAediting_246162	chr2_226785481_-	SINE	Alu	AluSz
CAediting_246163	chr2_226785491_-	SINE	Alu	AluSz
CAediting_246164	chr2_226785509_-	SINE	Alu	AluSz
CAediting_246165	chr2_226785516_-	SINE	Alu	AluSz
CAediting_246166	chr2_226785520_-	SINE	Alu	AluSz
CAediting_246167	chr2_226785589_-	SINE	Alu	AluSz
CAediting_246168	chr2_226785599_-	SINE	Alu	AluSz
CAediting_246169	chr2_226785601_-	SINE	Alu	AluSz

Top

RNA A-to-I editing events in the alternative splicing sites for IRS1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000169047.5.IRS1.

Correlation between RNA A-to-I editing and PSI for ENSG00000169047.5.IRS1.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for IRS1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BRCA.CAediting_246128.ENSG00000169047.IRS1.png
Soverview

Top

Protein coding region RNA A-to-I editings for IRS1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for IRS1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for IRS1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for IRS1

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

Top

Relation with cancer stages for IRS1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

Top

Relation with survival for IRS1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

Top

RelatedDrugs for IRS1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for IRS1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
IRS1	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	9	CTD_human;UNIPROT
IRS1	C2239176	Liver carcinoma	2	CTD_human
IRS1	C0002152	Alloxan Diabetes	1	CTD_human
IRS1	C0007621	Neoplastic Cell Transformation	1	CTD_human
IRS1	C0010054	Coronary Arteriosclerosis	1	CTD_human
IRS1	C0010068	Coronary heart disease	1	CTD_human
IRS1	C0011849	Diabetes Mellitus	1	CTD_human
IRS1	C0011853	Diabetes Mellitus, Experimental	1	CTD_human
IRS1	C0020459	Hyperinsulinism	1	CTD_human
IRS1	C0020473	Hyperlipidemia	1	CTD_human
IRS1	C0021655	Insulin Resistance	1	CTD_human
IRS1	C0028754	Obesity	1	CTD_human
IRS1	C0032927	Precancerous Conditions	1	CTD_human
IRS1	C0033578	Prostatic Neoplasms	1	CTD_human
IRS1	C0038433	Streptozotocin Diabetes	1	CTD_human
IRS1	C0282313	Condition, Preneoplastic	1	CTD_human
IRS1	C0376358	Malignant neoplasm of prostate	1	CTD_human
IRS1	C0920563	Insulin Sensitivity	1	CTD_human
IRS1	C1168401	Squamous cell carcinoma of the head and neck	1	CTD_human
IRS1	C1257963	Endogenous Hyperinsulinism	1	CTD_human
IRS1	C1257964	Exogenous Hyperinsulinism	1	CTD_human
IRS1	C1257965	Compensatory Hyperinsulinemia	1	CTD_human
IRS1	C1706412	Lipidemias	1	CTD_human
IRS1	C1956346	Coronary Artery Disease	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene