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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: INSL3 (CAeditome ID:3640) |
Gene summary for INSL3 |
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Gene information | Gene symbol | INSL3 | Gene ID | 3640 |
Gene name | insulin like 3 | |
Synonyms | RLF|RLNL|ley-I-L | |
Cytomap | 19p13.11 | |
Type of gene | protein-coding | |
Description | insulin-like 3insulin-like 3 (Leydig cell)leydig insulin -like hormoneleydig insulin-like peptideprepro-INSL3relaxin-like factor b | |
Modification date | 20210518 | |
UniProtAcc | P51460 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
INSL3 | GO:0010634 | Insulin-like 3 | 23539510 |
INSL3 | GO:0090303 | Insulin-like 3 | 23539510 |
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RNA A-to-I events for INSL3 |
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CAediting_1317602(17820011, -), CAediting_1317603(17820059, -), CAediting_1317604(17820144, -), CAediting_1317605(17820428, -), |
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RNA editing positional annotations for INSL3 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_1317605 | chr19_17820428_- | nonsynonymous SNV | ENST00000379695.5 | c.A253G | p.T85A | D | . | N |
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CAeditome ID | Position | Variant type |
CAediting_1317602 | chr19_17820011_- | intronic |
CAediting_1317603 | chr19_17820059_- | intronic |
CAediting_1317604 | chr19_17820144_- | intronic |
CAediting_1317605 | chr19_17820428_- | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_1317602 | chr19_17820011_- | SINE | Alu | AluJb |
CAediting_1317603 | chr19_17820059_- | SINE | Alu | AluJb |
CAediting_1317604 | chr19_17820144_- | SINE | Alu | AluJb |
CAediting_1317605 | chr19_17820428_- | SINE | Alu | AluJb |
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RNA A-to-I editing events in the alternative splicing sites for INSL3 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for INSL3 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for INSL3 |
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The effects of the RNA editing to the miRNA binding sites for INSL3 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for INSL3 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for INSL3 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for INSL3 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for INSL3 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for INSL3 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for INSL3 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
INSL3 | C0010417 | Cryptorchidism | 5 | CTD_human;UNIPROT |
INSL3 | C0431663 | Bilateral Cryptorchidism | 2 | CTD_human |
INSL3 | C0431664 | Unilateral Cryptorchidism | 2 | CTD_human |
INSL3 | C1563730 | Abdominal Cryptorchidism | 2 | CTD_human |
INSL3 | C1563731 | Inguinal Cryptorchidism | 2 | CTD_human |