Home

Download

Statistics

Examples

Help

Contact

Editing gene: IL12RB1 (CAeditome ID:3594)

Gene summary for IL12RB1

Gene summary

Gene information	Gene symbol	IL12RB1
	Gene ID	3594
	Gene name	interleukin 12 receptor subunit beta 1
	Synonyms	CD212\|IL-12R-BETA1\|IL12RB\|IMD30
	Cytomap	19p13.11
	Type of gene	protein-coding
	Description	interleukin-12 receptor subunit beta-1IL-12 receptor beta componentIL-12 receptor subunit beta-1IL-12R subunit beta-1cluster of differentiation 212interleukin 12 receptor, beta 1interleukin-12 receptor beta-1 chain
	Modification date	20210518
	UniProtAcc	P42701
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
IL12RB1	GO:0016517	Interleukin-12 receptor subunit beta-1	8943050
IL12RB1	GO:0042020	Interleukin-12 receptor subunit beta-1	12023369
IL12RB1	GO:0002230	Interleukin-12 receptor subunit beta-1	12421946
IL12RB1	GO:0002827	Interleukin-12 receptor subunit beta-1	15114670
IL12RB1	GO:0032729	Interleukin-12 receptor subunit beta-1	11114383
IL12RB1	GO:0042104	Interleukin-12 receptor subunit beta-1	11114383
IL12RB1	GO:0071346	Interleukin-12 receptor subunit beta-1	12023369
IL12RB1	GO:0042022	Interleukin-12 receptor subunit beta-1	12023369
IL12RB1	GO:0072536	Interleukin-12 receptor subunit beta-1	12023369

Top

RNA A-to-I events for IL12RB1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000096996.14

RNA A-to-I editing events in Cancer.

CAediting_1318251(18062664, -), CAediting_1318252(18062733, -), CAediting_1318253(18062738, -), CAediting_1318254(18070012, -), CAediting_1318255(18070027, -), CAediting_1318256(18070031, -), CAediting_1318257(18070040, -), CAediting_1318258(18070171, -), CAediting_1318259(18070175, -), CAediting_1318260(18070187, -), CAediting_1318261(18070682, -), CAediting_1318262(18070688, -), CAediting_1318263(18070695, -), CAediting_1318264(18070709, -), CAediting_1318265(18070734, -), CAediting_1318266(18070747, -), CAediting_1318267(18070768, -), CAediting_1318268(18070774, -), CAediting_1318269(18070813, -), CAediting_1318270(18070823, -), CAediting_1318271(18070826, -), CAediting_1318272(18070833, -), CAediting_1318273(18070836, -), CAediting_1318274(18070863, -), CAediting_1318275(18070869, -), CAediting_1318276(18070875, -), CAediting_1318277(18070876, -), CAediting_1318278(18070883, -), CAediting_1318279(18070888, -), CAediting_1318280(18070922, -), CAediting_1318281(18070930, -), CAediting_1318282(18070934, -), CAediting_1318283(18070992, -), CAediting_1318284(18071002, -), CAediting_1318285(18071032, -), CAediting_1318286(18071057, -), CAediting_1318287(18071071, -), CAediting_1318288(18071074, -), CAediting_1318289(18071129, -), CAediting_1318290(18071130, -), CAediting_1318291(18071147, -), CAediting_1318292(18071151, -), CAediting_1318293(18071155, -), CAediting_1318294(18071161, -), CAediting_1318295(18071207, -), CAediting_1318296(18071210, -), CAediting_1318297(18071216, -), CAediting_1318298(18071223, -), CAediting_1318299(18071224, -), CAediting_1318300(18071250, -), CAediting_1318301(18071260, -), CAediting_1318302(18071263, -), CAediting_1318303(18071287, -), CAediting_1318304(18071289, -), CAediting_1318305(18071290, -), CAediting_1318306(18071294, -), CAediting_1318307(18071296, -), CAediting_1318308(18071309, -), CAediting_1318309(18071310, -), CAediting_1318310(18071325, -), CAediting_1318311(18075357, -), CAediting_1318312(18076574, -), CAediting_1318313(18077195, -), CAediting_1318314(18077279, -), CAediting_1318315(18077895, -), CAediting_1318316(18077921, -), CAediting_1318317(18078026, -), CAediting_1318318(18078033, -), CAediting_1318319(18078307, -), CAediting_1318320(18078324, -), CAediting_1318321(18078942, -), CAediting_1318322(18079175, -), CAediting_1318323(18080085, -), CAediting_1318324(18080086, -), CAediting_1318325(18080118, -), CAediting_1318326(18080121, -), CAediting_1318327(18080123, -), CAediting_1318328(18080124, -), CAediting_1318329(18080153, -), CAediting_1318330(18080171, -), CAediting_1318331(18080180, -), CAediting_1318332(18080184, -), CAediting_1318333(18080193, -), CAediting_1318334(18080194, -), CAediting_1318335(18080317, -), CAediting_1318336(18080389, -), CAediting_1318337(18080399, -), CAediting_1318338(18094214, -), CAediting_1318339(18095989, -),

Top

RNA editing positional annotations for IL12RB1 using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_1318297	chr19_18071216_-	nonsynonymous SNV	ENST00000322153.10	c.A1139G	p.Y380C	.	B	N

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1318251	chr19_18062664_-	intronic
CAediting_1318252	chr19_18062733_-	intronic
CAediting_1318253	chr19_18062738_-	intronic
CAediting_1318254	chr19_18070012_-	intronic
CAediting_1318255	chr19_18070027_-	intronic
CAediting_1318256	chr19_18070031_-	intronic
CAediting_1318257	chr19_18070040_-	intronic
CAediting_1318258	chr19_18070171_-	intronic
CAediting_1318259	chr19_18070175_-	intronic
CAediting_1318260	chr19_18070187_-	intronic
CAediting_1318261	chr19_18070682_-	UTR3
CAediting_1318262	chr19_18070688_-	UTR3
CAediting_1318263	chr19_18070695_-	UTR3
CAediting_1318264	chr19_18070709_-	UTR3
CAediting_1318265	chr19_18070734_-	UTR3
CAediting_1318266	chr19_18070747_-	UTR3
CAediting_1318267	chr19_18070768_-	UTR3
CAediting_1318268	chr19_18070774_-	UTR3
CAediting_1318269	chr19_18070813_-	UTR3
CAediting_1318270	chr19_18070823_-	UTR3
CAediting_1318271	chr19_18070826_-	UTR3
CAediting_1318272	chr19_18070833_-	UTR3
CAediting_1318273	chr19_18070836_-	UTR3
CAediting_1318274	chr19_18070863_-	UTR3
CAediting_1318275	chr19_18070869_-	UTR3
CAediting_1318276	chr19_18070875_-	UTR3
CAediting_1318277	chr19_18070876_-	UTR3
CAediting_1318278	chr19_18070883_-	UTR3
CAediting_1318279	chr19_18070888_-	UTR3
CAediting_1318280	chr19_18070922_-	UTR3
CAediting_1318281	chr19_18070930_-	UTR3
CAediting_1318282	chr19_18070934_-	UTR3
CAediting_1318283	chr19_18070992_-	UTR3
CAediting_1318284	chr19_18071002_-	UTR3
CAediting_1318285	chr19_18071032_-	UTR3
CAediting_1318286	chr19_18071057_-	UTR3
CAediting_1318287	chr19_18071071_-	UTR3
CAediting_1318288	chr19_18071074_-	UTR3
CAediting_1318289	chr19_18071129_-	UTR3
CAediting_1318290	chr19_18071130_-	UTR3
CAediting_1318291	chr19_18071147_-	UTR3
CAediting_1318292	chr19_18071151_-	UTR3
CAediting_1318293	chr19_18071155_-	UTR3
CAediting_1318294	chr19_18071161_-	UTR3
CAediting_1318295	chr19_18071207_-	UTR3
CAediting_1318296	chr19_18071210_-	exonic
CAediting_1318297	chr19_18071216_-	exonic
CAediting_1318298	chr19_18071223_-	exonic
CAediting_1318299	chr19_18071224_-	exonic
CAediting_1318300	chr19_18071250_-	exonic
CAediting_1318301	chr19_18071260_-	exonic
CAediting_1318302	chr19_18071263_-	exonic
CAediting_1318303	chr19_18071287_-	exonic
CAediting_1318304	chr19_18071289_-	exonic
CAediting_1318305	chr19_18071290_-	exonic
CAediting_1318306	chr19_18071294_-	exonic
CAediting_1318307	chr19_18071296_-	exonic
CAediting_1318308	chr19_18071309_-	exonic
CAediting_1318309	chr19_18071310_-	exonic
CAediting_1318310	chr19_18071325_-	exonic
CAediting_1318311	chr19_18075357_-	intronic
CAediting_1318312	chr19_18076574_-	intronic
CAediting_1318313	chr19_18077195_-	intronic
CAediting_1318314	chr19_18077279_-	intronic
CAediting_1318315	chr19_18077895_-	intronic
CAediting_1318316	chr19_18077921_-	intronic
CAediting_1318317	chr19_18078026_-	intronic
CAediting_1318318	chr19_18078033_-	intronic
CAediting_1318319	chr19_18078307_-	intronic
CAediting_1318320	chr19_18078324_-	intronic
CAediting_1318321	chr19_18078942_-	intronic
CAediting_1318322	chr19_18079175_-	intronic
CAediting_1318323	chr19_18080085_-	intronic
CAediting_1318324	chr19_18080086_-	intronic
CAediting_1318325	chr19_18080118_-	intronic
CAediting_1318326	chr19_18080121_-	intronic
CAediting_1318327	chr19_18080123_-	intronic
CAediting_1318328	chr19_18080124_-	intronic
CAediting_1318329	chr19_18080153_-	intronic
CAediting_1318330	chr19_18080171_-	intronic
CAediting_1318331	chr19_18080180_-	intronic
CAediting_1318332	chr19_18080184_-	intronic
CAediting_1318333	chr19_18080193_-	intronic
CAediting_1318334	chr19_18080194_-	intronic
CAediting_1318335	chr19_18080317_-	intronic
CAediting_1318336	chr19_18080389_-	intronic
CAediting_1318337	chr19_18080399_-	intronic
CAediting_1318338	chr19_18094214_-	intronic
CAediting_1318339	chr19_18095989_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1318251	chr19_18062664_-	SINE	Alu	AluSq2
CAediting_1318252	chr19_18062733_-	SINE	Alu	AluSq2
CAediting_1318253	chr19_18062738_-	SINE	Alu	AluSq2
CAediting_1318254	chr19_18070012_-	SINE	Alu	AluSx3
CAediting_1318255	chr19_18070027_-	SINE	Alu	AluSx3
CAediting_1318256	chr19_18070031_-	SINE	Alu	AluSx3
CAediting_1318257	chr19_18070040_-	SINE	Alu	AluSx3
CAediting_1318258	chr19_18070171_-	SINE	Alu	AluSx3
CAediting_1318259	chr19_18070175_-	SINE	Alu	AluSx3
CAediting_1318260	chr19_18070187_-	SINE	Alu	AluSx3
CAediting_1318261	chr19_18070682_-	SINE	Alu	AluJo
CAediting_1318262	chr19_18070688_-	SINE	Alu	AluJo
CAediting_1318263	chr19_18070695_-	SINE	Alu	AluJo
CAediting_1318264	chr19_18070709_-	SINE	Alu	AluJo
CAediting_1318265	chr19_18070734_-	SINE	Alu	AluJo
CAediting_1318266	chr19_18070747_-	SINE	Alu	AluJo
CAediting_1318267	chr19_18070768_-	SINE	Alu	AluJo
CAediting_1318268	chr19_18070774_-	SINE	Alu	AluJo
CAediting_1318269	chr19_18070813_-	SINE	Alu	AluJo
CAediting_1318270	chr19_18070823_-	SINE	Alu	AluJo
CAediting_1318271	chr19_18070826_-	SINE	Alu	AluJo
CAediting_1318272	chr19_18070833_-	SINE	Alu	AluJo
CAediting_1318273	chr19_18070836_-	SINE	Alu	AluJo
CAediting_1318274	chr19_18070863_-	SINE	Alu	AluJo
CAediting_1318275	chr19_18070869_-	SINE	Alu	AluJo
CAediting_1318276	chr19_18070875_-	SINE	Alu	AluJo
CAediting_1318277	chr19_18070876_-	SINE	Alu	AluJo
CAediting_1318278	chr19_18070883_-	SINE	Alu	AluJo
CAediting_1318279	chr19_18070888_-	SINE	Alu	AluJo
CAediting_1318280	chr19_18070922_-	SINE	Alu	AluJo
CAediting_1318281	chr19_18070930_-	SINE	Alu	AluJo
CAediting_1318282	chr19_18070934_-	SINE	Alu	AluJo
CAediting_1318283	chr19_18070992_-	SINE	Alu	AluSx
CAediting_1318284	chr19_18071002_-	SINE	Alu	AluSx
CAediting_1318285	chr19_18071032_-	SINE	Alu	AluSx
CAediting_1318286	chr19_18071057_-	SINE	Alu	AluSx
CAediting_1318287	chr19_18071071_-	SINE	Alu	AluSx
CAediting_1318288	chr19_18071074_-	SINE	Alu	AluSx
CAediting_1318289	chr19_18071129_-	SINE	Alu	AluSx1
CAediting_1318290	chr19_18071130_-	SINE	Alu	AluSx1
CAediting_1318291	chr19_18071147_-	SINE	Alu	AluSx1
CAediting_1318292	chr19_18071151_-	SINE	Alu	AluSx1
CAediting_1318293	chr19_18071155_-	SINE	Alu	AluSx1
CAediting_1318294	chr19_18071161_-	SINE	Alu	AluSx1
CAediting_1318295	chr19_18071207_-	SINE	Alu	AluSx1
CAediting_1318296	chr19_18071210_-	SINE	Alu	AluSx1
CAediting_1318297	chr19_18071216_-	SINE	Alu	AluSx1
CAediting_1318298	chr19_18071223_-	SINE	Alu	AluSx1
CAediting_1318299	chr19_18071224_-	SINE	Alu	AluSx1
CAediting_1318300	chr19_18071250_-	SINE	Alu	AluSx1
CAediting_1318301	chr19_18071260_-	SINE	Alu	AluSx1
CAediting_1318302	chr19_18071263_-	SINE	Alu	AluSx1
CAediting_1318303	chr19_18071287_-	SINE	Alu	AluSx1
CAediting_1318304	chr19_18071289_-	SINE	Alu	AluSx1
CAediting_1318305	chr19_18071290_-	SINE	Alu	AluSx1
CAediting_1318306	chr19_18071294_-	SINE	Alu	AluSx1
CAediting_1318307	chr19_18071296_-	SINE	Alu	AluSx1
CAediting_1318308	chr19_18071309_-	SINE	Alu	AluSx1
CAediting_1318309	chr19_18071310_-	SINE	Alu	AluSx1
CAediting_1318310	chr19_18071325_-	SINE	Alu	AluSx1
CAediting_1318311	chr19_18075357_-	SINE	Alu	AluSx1
CAediting_1318312	chr19_18076574_-	SINE	Alu	AluJb
CAediting_1318313	chr19_18077195_-	SINE	Alu	AluSx
CAediting_1318314	chr19_18077279_-	SINE	Alu	AluSx
CAediting_1318315	chr19_18077895_-	SINE	Alu	AluJb
CAediting_1318316	chr19_18077921_-	SINE	Alu	AluJb
CAediting_1318317	chr19_18078026_-	SINE	Alu	AluJb
CAediting_1318318	chr19_18078033_-	SINE	Alu	AluJb
CAediting_1318319	chr19_18078307_-	SINE	Alu	AluSx1
CAediting_1318320	chr19_18078324_-	SINE	Alu	AluSx1
CAediting_1318321	chr19_18078942_-	SINE	Alu	FLAM_C
CAediting_1318322	chr19_18079175_-	SINE	Alu	AluSx1
CAediting_1318323	chr19_18080085_-	SINE	Alu	AluSx
CAediting_1318324	chr19_18080086_-	SINE	Alu	AluSx
CAediting_1318325	chr19_18080118_-	SINE	Alu	AluSx
CAediting_1318326	chr19_18080121_-	SINE	Alu	AluSx
CAediting_1318327	chr19_18080123_-	SINE	Alu	AluSx
CAediting_1318328	chr19_18080124_-	SINE	Alu	AluSx
CAediting_1318329	chr19_18080153_-	SINE	Alu	AluSx
CAediting_1318330	chr19_18080171_-	SINE	Alu	AluSx
CAediting_1318331	chr19_18080180_-	SINE	Alu	AluSx
CAediting_1318332	chr19_18080184_-	SINE	Alu	AluSx
CAediting_1318333	chr19_18080193_-	SINE	Alu	AluSx
CAediting_1318334	chr19_18080194_-	SINE	Alu	AluSx
CAediting_1318335	chr19_18080317_-	SINE	Alu	AluSc
CAediting_1318336	chr19_18080389_-	SINE	Alu	AluSc
CAediting_1318337	chr19_18080399_-	SINE	Alu	AluSc
CAediting_1318338	chr19_18094214_-	SINE	Alu	AluSx
CAediting_1318339	chr19_18095989_-	SINE	Alu	AluJb

Top

RNA A-to-I editing events in the alternative splicing sites for IL12RB1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000096996.14.IL12RB1.

Correlation between RNA A-to-I editing and PSI for ENSG00000096996.14.IL12RB1.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for IL12RB1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Top

Protein coding region RNA A-to-I editings for IL12RB1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for IL12RB1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1318262	chr19_18070688_-	ENSG00000096996.14	ENST00000322153	hsa-miR-383-3p	18070688	18070694	7mer-m8	18070687	18070705	140.00	-14.49
CAediting_1318262	chr19_18070688_-	ENSG00000096996.14	ENST00000322153	hsa-miR-7977	18070685	18070691	7mer-m8	18070684	18070701	140.00	-13.07
CAediting_1318272	chr19_18070833_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4691-3p	18070829	18070835	7mer-m8	18070828	18070854	152.00	-28.97
CAediting_1318275	chr19_18070869_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4497	18070867	18070873	7mer-m8	18070866	18070882	140.00	-18.38
CAediting_1318280	chr19_18070922_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4523	18070920	18070926	7mer-m8	18070919	18070936	150.00	-24.41
CAediting_1318281	chr19_18070930_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4267	18070929	18070935	7mer-m8	18070928	18070943	142.00	-16.70
CAediting_1318264	chr19_18070709_-	ENSG00000096996.14	ENST00000322153	hsa-miR-139-3p	18070703	18070710	8mer-1a	18070703	18070726	144.00	-22.18
CAediting_1318264	chr19_18070709_-	ENSG00000096996.14	ENST00000322153	hsa-miR-483-5p	18070706	18070712	7mer-m8	18070705	18070726	152.00	-22.29
CAediting_1318265	chr19_18070734_-	ENSG00000096996.14	ENST00000322153	hsa-miR-28-5p	18070729	18070735	7mer-m8	18070728	18070748	151.00	-22.03
CAediting_1318265	chr19_18070734_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3139	18070729	18070735	7mer-m8	18070728	18070750	165.00	-26.52
CAediting_1318265	chr19_18070734_-	ENSG00000096996.14	ENST00000322153	hsa-miR-708-5p	18070729	18070735	7mer-m8	18070728	18070749	150.00	-22.21
CAediting_1318266	chr19_18070747_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3940-3p	18070743	18070749	7mer-m8	18070742	18070763	140.00	-20.94
CAediting_1318267	chr19_18070768_-	ENSG00000096996.14	ENST00000322153	hsa-miR-340-3p	18070767	18070773	7mer-m8	18070766	18070787	141.00	-15.89
CAediting_1318267	chr19_18070768_-	ENSG00000096996.14	ENST00000322153	hsa-miR-6827-3p	18070767	18070773	7mer-m8	18070766	18070786	147.00	-16.55
CAediting_1318270	chr19_18070823_-	ENSG00000096996.14	ENST00000322153	hsa-miR-17-3p	18070819	18070826	8mer-1a	18070819	18070841	149.00	-21.86
CAediting_1318271	chr19_18070826_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4323	18070823	18070830	8mer-1a	18070823	18070841	147.00	-19.79
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3670	18070872	18070878	7mer-m8	18070871	18070894	155.00	-18.12
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3670	18070872	18070878	7mer-m8	18070871	18070894	155.00	-18.12
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3670	18070872	18070878	7mer-m8	18070871	18070894	155.00	-18.12
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3670	18070872	18070878	7mer-m8	18070871	18070894	155.00	-18.12
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4300	18070869	18070876	8mer-1a	18070869	18070886	143.00	-16.64
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-5591-5p	18070869	18070876	8mer-1a	18070869	18070891	151.00	-21.24
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-6726-5p	18070869	18070876	8mer-1a	18070869	18070889	171.00	-29.38
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-920	18070869	18070876	8mer-1a	18070869	18070889	153.00	-25.67
CAediting_1318277	chr19_18070876_-	ENSG00000096996.14	ENST00000322153	hsa-miR-1289	18070871	18070877	7mer-m8	18070870	18070890	162.00	-24.32
CAediting_1318277	chr19_18070876_-	ENSG00000096996.14	ENST00000322153	hsa-miR-1289	18070871	18070877	7mer-m8	18070870	18070890	162.00	-24.32
CAediting_1318285	chr19_18071032_-	ENSG00000096996.14	ENST00000322153	hsa-miR-28-5p	18071027	18071033	7mer-m8	18071026	18071046	143.00	-18.76
CAediting_1318285	chr19_18071032_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3139	18071027	18071033	7mer-m8	18071026	18071048	157.00	-23.25
CAediting_1318285	chr19_18071032_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4538	18071030	18071035	6mer	18071029	18071052	149.00	-29.79
CAediting_1318285	chr19_18071032_-	ENSG00000096996.14	ENST00000322153	hsa-miR-708-5p	18071027	18071033	7mer-m8	18071026	18071047	154.00	-22.59
CAediting_1318289	chr19_18071129_-	ENSG00000096996.14	ENST00000322153	hsa-miR-326	18071127	18071133	7mer-m8	18071126	18071145	140.00	-15.33
CAediting_1318289	chr19_18071129_-	ENSG00000096996.14	ENST00000322153	hsa-miR-330-5p	18071127	18071133	7mer-m8	18071126	18071147	140.00	-22.45
CAediting_1318289	chr19_18071129_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4314	18071128	18071134	7mer-m8	18071127	18071144	140.00	-18.79
CAediting_1318289	chr19_18071129_-	ENSG00000096996.14	ENST00000322153	hsa-miR-514a-5p	18071126	18071132	7mer-m8	18071125	18071145	154.00	-19.31
CAediting_1318289	chr19_18071129_-	ENSG00000096996.14	ENST00000322153	hsa-miR-514a-5p	18071126	18071132	7mer-m8	18071125	18071145	154.00	-19.31
CAediting_1318289	chr19_18071129_-	ENSG00000096996.14	ENST00000322153	hsa-miR-514a-5p	18071126	18071132	7mer-m8	18071125	18071145	154.00	-19.31
CAediting_1318292	chr19_18071151_-	ENSG00000096996.14	ENST00000322153	hsa-miR-1255b-2-3p	18071150	18071156	7mer-m8	18071149	18071170	140.00	-8.70
CAediting_1318292	chr19_18071151_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4776-5p	18071147	18071153	7mer-m8	18071146	18071169	151.00	-24.89
CAediting_1318292	chr19_18071151_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4776-5p	18071147	18071153	7mer-m8	18071146	18071169	151.00	-24.89
CAediting_1318292	chr19_18071151_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4800-5p	18071146	18071152	7mer-m8	18071145	18071170	147.00	-24.71
CAediting_1318293	chr19_18071155_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3622a-3p	18071151	18071158	8mer-1a	18071151	18071172	144.00	-13.89
CAediting_1318293	chr19_18071155_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3622b-3p	18071151	18071158	8mer-1a	18071151	18071171	153.00	-19.33
CAediting_1318293	chr19_18071155_-	ENSG00000096996.14	ENST00000322153	hsa-miR-544b	18071154	18071160	7mer-m8	18071153	18071173	157.00	-19.04
CAediting_1318293	chr19_18071155_-	ENSG00000096996.14	ENST00000322153	hsa-miR-7162-3p	18071155	18071161	7mer-m8	18071154	18071174	142.00	-17.47
CAediting_1318261	chr19_18070682_-	ENSG00000096996.14	ENST00000322153	hsa-miR-106a-3p	18070680	18070685	6mer	18070679	18070700	141.00	-21.13
CAediting_1318263	chr19_18070695_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3192-5p	18070694	18070701	8mer-1a	18070694	18070717	156.00	-28.88
CAediting_1318263	chr19_18070695_-	ENSG00000096996.14	ENST00000322153	hsa-miR-326	18070693	18070699	7mer-m8	18070692	18070711	140.00	-13.25
CAediting_1318263	chr19_18070695_-	ENSG00000096996.14	ENST00000322153	hsa-miR-330-5p	18070693	18070699	7mer-m8	18070692	18070713	140.00	-18.54
CAediting_1318263	chr19_18070695_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4314	18070694	18070700	7mer-m8	18070693	18070710	150.00	-21.81
CAediting_1318263	chr19_18070695_-	ENSG00000096996.14	ENST00000322153	hsa-miR-514a-5p	18070692	18070698	7mer-m8	18070691	18070713	151.00	-18.80
CAediting_1318263	chr19_18070695_-	ENSG00000096996.14	ENST00000322153	hsa-miR-514a-5p	18070692	18070698	7mer-m8	18070691	18070713	151.00	-18.80
CAediting_1318263	chr19_18070695_-	ENSG00000096996.14	ENST00000322153	hsa-miR-514a-5p	18070692	18070698	7mer-m8	18070691	18070713	151.00	-18.80
CAediting_1318290	chr19_18071130_-	ENSG00000096996.14	ENST00000322153	hsa-miR-6771-5p	18071128	18071135	8mer-1a	18071128	18071147	161.00	-31.74
CAediting_1318291	chr19_18071147_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3937	18071143	18071149	7mer-m8	18071142	18071164	142.00	-22.99

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1318291	chr19_18071147_-	ENSG00000096996.14	ENST00000322153	hsa-miR-12114	18071144	18071150	7mer-m8	18071143	18071162	152	-28.65
CAediting_1318268	chr19_18070774_-	ENSG00000096996.14	ENST00000322153	hsa-miR-1283	18070772	18070779	8mer-1a	18070772	18070793	150	-11.59
CAediting_1318268	chr19_18070774_-	ENSG00000096996.14	ENST00000322153	hsa-miR-1283	18070772	18070779	8mer-1a	18070772	18070793	150	-11.59
CAediting_1318278	chr19_18070883_-	ENSG00000096996.14	ENST00000322153	hsa-miR-17-3p	18070882	18070888	7mer-m8	18070881	18070901	153	-19.16
CAediting_1318290	chr19_18071130_-	ENSG00000096996.14	ENST00000322153	hsa-miR-30b-3p	18071129	18071136	8mer-1a	18071129	18071150	147	-18
CAediting_1318291	chr19_18071147_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3165	18071145	18071151	7mer-m8	18071144	18071163	149	-18.69
CAediting_1318279	chr19_18070888_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3174	18070886	18070891	6mer	18070885	18070907	142	-20.93
CAediting_1318274	chr19_18070863_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3614-5p	18070858	18070864	7mer-1a	18070858	18070887	148	-27.11
CAediting_1318291	chr19_18071147_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3665	18071142	18071148	7mer-m8	18071141	18071158	140	-16.03
CAediting_1318287	chr19_18071071_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3675-3p	18071066	18071072	7mer-m8	18071065	18071086	145	-12.58
CAediting_1318290	chr19_18071130_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3689a-3p	18071129	18071136	8mer-1a	18071129	18071150	141	-19.53
CAediting_1318290	chr19_18071130_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3689b-3p	18071129	18071136	8mer-1a	18071129	18071150	141	-19.58
CAediting_1318290	chr19_18071130_-	ENSG00000096996.14	ENST00000322153	hsa-miR-3689c	18071129	18071136	8mer-1a	18071129	18071150	141	-19.58
CAediting_1318282	chr19_18070934_-	ENSG00000096996.14	ENST00000322153	hsa-miR-371b-5p	18070933	18070939	7mer-m8	18070932	18070952	146	-7.97
CAediting_1318282	chr19_18070934_-	ENSG00000096996.14	ENST00000322153	hsa-miR-373-5p	18070933	18070939	7mer-m8	18070932	18070953	140	-8.34
CAediting_1318280	chr19_18070922_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4251	18070921	18070927	7mer-m8	18070920	18070936	142	-13.08
CAediting_1318275	chr19_18070869_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4314	18070867	18070873	7mer-m8	18070866	18070883	140	-14.12
CAediting_1318280	chr19_18070922_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4329	18070921	18070926	6mer	18070920	18070938	144	-22.04
CAediting_1318284	chr19_18071002_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4478	18070998	18071004	7mer-m8	18070997	18071013	154	-23.41
CAediting_1318280	chr19_18070922_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4494	18070917	18070923	7mer-m8	18070916	18070940	150	-18.02
CAediting_1318280	chr19_18070922_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4499	18070918	18070924	7mer-m8	18070917	18070933	151	-17.04
CAediting_1318276	chr19_18070875_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4653-3p	18070871	18070876	6mer	18070870	18070892	141	-26.72
CAediting_1318277	chr19_18070876_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4653-3p	18070871	18070876	6mer	18070870	18070892	141	-26.72
CAediting_1318269	chr19_18070813_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4666b	18070813	18070819	7mer-m8	18070812	18070830	152	-17.8
CAediting_1318268	chr19_18070774_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4684-5p	18070770	18070776	7mer-m8	18070769	18070790	143	-8.1
CAediting_1318284	chr19_18071002_-	ENSG00000096996.14	ENST00000322153	hsa-miR-485-5p	18070997	18071003	7mer-m8	18070996	18071017	149	-18.56
CAediting_1318273	chr19_18070836_-	ENSG00000096996.14	ENST00000322153	hsa-miR-508-5p	18070833	18070840	8mer-1a	18070833	18070855	155	-22.86
CAediting_1318268	chr19_18070774_-	ENSG00000096996.14	ENST00000322153	hsa-miR-519a-2-5p	18070770	18070777	8mer-1a	18070770	18070790	153	-13.81
CAediting_1318273	chr19_18070836_-	ENSG00000096996.14	ENST00000322153	hsa-miR-520a-5p	18070836	18070842	7mer-m8	18070835	18070857	149	-20.08
CAediting_1318268	chr19_18070774_-	ENSG00000096996.14	ENST00000322153	hsa-miR-520b-5p	18070770	18070777	8mer-1a	18070770	18070790	153	-13.81
CAediting_1318273	chr19_18070836_-	ENSG00000096996.14	ENST00000322153	hsa-miR-525-5p	18070836	18070842	7mer-m8	18070835	18070855	145	-20.73
CAediting_1318271	chr19_18070826_-	ENSG00000096996.14	ENST00000322153	hsa-miR-5588-3p	18070823	18070830	8mer-1a	18070823	18070841	154	-22.9
CAediting_1318272	chr19_18070833_-	ENSG00000096996.14	ENST00000322153	hsa-miR-5690	18070829	18070835	7mer-m8	18070828	18070848	147	-19.59
CAediting_1318267	chr19_18070768_-	ENSG00000096996.14	ENST00000322153	hsa-miR-5699-3p	18070766	18070772	7mer-m8	18070765	18070786	148	-15.22
CAediting_1318266	chr19_18070747_-	ENSG00000096996.14	ENST00000322153	hsa-miR-612	18070746	18070752	7mer-m8	18070745	18070769	148	-23.68
CAediting_1318282	chr19_18070934_-	ENSG00000096996.14	ENST00000322153	hsa-miR-616-5p	18070933	18070939	7mer-m8	18070932	18070953	140	-5.7
CAediting_1318274	chr19_18070863_-	ENSG00000096996.14	ENST00000322153	hsa-miR-627-5p	18070862	18070869	8mer-1a	18070862	18070883	141	-16.17
CAediting_1318266	chr19_18070747_-	ENSG00000096996.14	ENST00000322153	hsa-miR-661	18070744	18070750	7mer-m8	18070743	18070767	142	-20.71
CAediting_1318290	chr19_18071130_-	ENSG00000096996.14	ENST00000322153	hsa-miR-6779-5p	18071129	18071136	8mer-1a	18071129	18071152	143	-22.97
CAediting_1318279	chr19_18070888_-	ENSG00000096996.14	ENST00000322153	hsa-miR-6807-5p	18070888	18070894	7mer-m8	18070887	18070906	146	-17.99
CAediting_1318267	chr19_18070768_-	ENSG00000096996.14	ENST00000322153	hsa-miR-6818-3p	18070768	18070774	7mer-m8	18070767	18070788	140	-11.1
CAediting_1318280	chr19_18070922_-	ENSG00000096996.14	ENST00000322153	hsa-miR-6857-3p	18070919	18070925	7mer-m8	18070918	18070938	145	-14.37
CAediting_1318266	chr19_18070747_-	ENSG00000096996.14	ENST00000322153	hsa-miR-6860	18070746	18070752	7mer-m8	18070745	18070765	150	-24.56
CAediting_1318284	chr19_18071002_-	ENSG00000096996.14	ENST00000322153	hsa-miR-7160-5p	18071000	18071006	7mer-m8	18070999	18071016	148	-19.34
CAediting_1318284	chr19_18071002_-	ENSG00000096996.14	ENST00000322153	hsa-miR-7162-3p	18071001	18071007	7mer-m8	18071000	18071018	150	-18.37
CAediting_1318286	chr19_18071057_-	ENSG00000096996.14	ENST00000322153	hsa-miR-7855-5p	18071054	18071059	6mer	18071053	18071072	140	-18.97
CAediting_1318271	chr19_18070826_-	ENSG00000096996.14	ENST00000322153	hsa-miR-7977	18070826	18070832	7mer-m8	18070825	18070842	143	-14.78
CAediting_1318274	chr19_18070863_-	ENSG00000096996.14	ENST00000322153	hsa-miR-8081	18070862	18070868	7mer-m8	18070861	18070883	145	-13.97
CAediting_1318263	chr19_18070695_-	ENSG00000096996.14	ENST00000322153	hsa-miR-887-5p	18070694	18070701	8mer-1a	18070694	18070714	140	-11.48
CAediting_1318289	chr19_18071129_-	ENSG00000096996.14	ENST00000322153	hsa-miR-887-5p	18071128	18071135	8mer-1a	18071128	18071149	148	-16.93
CAediting_1318290	chr19_18071130_-	ENSG00000096996.14	ENST00000322153	hsa-miR-887-5p	18071128	18071135	8mer-1a	18071128	18071149	148	-16.93
CAediting_1318266	chr19_18070747_-	ENSG00000096996.14	ENST00000322153	hsa-miR-939-3p	18070745	18070751	7mer-m8	18070744	18070764	140	-15.63

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000096996.14	ENST00000593993	hsa-miR-200b-3p	18059241	18059247	7mer-m8	18059240	18059261	149	-17.97
CAediting_393	chr1_1167164_+	ENSG00000096996.14	ENST00000600835	hsa-miR-200b-3p	18059241	18059247	7mer-m8	18059240	18059261	149	-17.97
CAediting_748296	chr10_51299626_+	ENSG00000096996.14	ENST00000322153	hsa-miR-605-3p	18071020	18071027	8mer-1a	18071020	18071044	149	-20.98
CAediting_393	chr1_1167164_+	ENSG00000096996.14	ENST00000322153	hsa-miR-200b-3p	18070611	18070617	7mer-m8	18070610	18070631	140	-10.38
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000593993	hsa-miR-197-5p	18059290	18059296	7mer-m8	18059289	18059310	143	-21.05
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000593993	hsa-miR-197-5p	18059153	18059158	6mer	18059140	18059162	149	-29.05
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000593993	hsa-miR-197-5p	18059146	18059151	6mer	18059140	18059162	149	-29.05
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000593993	hsa-miR-197-5p	18059141	18059146	6mer	18059140	18059162	149	-29.05
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000600835	hsa-miR-197-5p	18059290	18059296	7mer-m8	18059289	18059310	143	-21.05
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000600835	hsa-miR-197-5p	18059153	18059158	6mer	18059140	18059162	149	-29.05
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000600835	hsa-miR-197-5p	18059146	18059151	6mer	18059140	18059162	149	-29.05
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000600835	hsa-miR-197-5p	18059141	18059146	6mer	18059140	18059162	149	-29.05
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000322153	hsa-miR-197-5p	18071007	18071014	8mer-1a	18071007	18071035	154	-33.11
CAediting_86358	chr1_109598906_+	ENSG00000096996.14	ENST00000322153	hsa-miR-197-5p	18070709	18070716	8mer-1a	18070699	18070719	149	-26.82
CAediting_396018	chr5_1062918_-	ENSG00000096996.14	ENST00000322153	hsa-miR-4635	18071154	18071160	7mer-m8	18071153	18071173	162	-22.6
CAediting_468389	chr6_31355314_-	ENSG00000096996.14	ENST00000593993	hsa-miR-6891-5p	18059492	18059498	7mer-m8	18059491	18059509	150	-19.01
CAediting_468389	chr6_31355314_-	ENSG00000096996.14	ENST00000593993	hsa-miR-6891-5p	18059066	18059072	7mer-m8	18059065	18059083	141	-14.49
CAediting_468389	chr6_31355314_-	ENSG00000096996.14	ENST00000600835	hsa-miR-6891-5p	18059492	18059498	7mer-m8	18059491	18059509	150	-19.01
CAediting_468389	chr6_31355314_-	ENSG00000096996.14	ENST00000600835	hsa-miR-6891-5p	18059066	18059072	7mer-m8	18059065	18059083	141	-14.49

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for IL12RB1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for IL12RB1

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
STAD	CAediting_1318262	chr19_18070688_-	.	.	0.0438053786395818	0.219238465673531	.	.
STAD	CAediting_1318304	chr19_18071289_-	.	.	0.000290027436628586	0.459006355550423	.	.
LUAD	CAediting_1318307	chr19_18071296_-	.	.	.	.	0.0299750340523775	0.282819357378382
KIRC	CAediting_1318307	chr19_18071296_-	.	.	0.0336283429039676	0.198305076155565	.	.
SKCM	CAediting_1318307	chr19_18071296_-	.	.	.	.	0.00417238788275932	0.338343499768668

Top

Relation with cancer stages for IL12RB1

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
STAD	pathologic_stage	CAediting_1318310	chr19_18071325_-	0.00618227636601006	-0.3937029705146

Top

Relation with survival for IL12RB1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

Top

RelatedDrugs for IL12RB1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for IL12RB1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
IL12RB1	C4013949	IMMUNODEFICIENCY 30	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
IL12RB1	C0007786	Brain Ischemia	1	CTD_human
IL12RB1	C0917798	Cerebral Ischemia	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene