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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: IFNAR2 (CAeditome ID:3455)

Gene summary for IFNAR2

check button Gene summary
Gene informationGene symbol

IFNAR2

Gene ID

3455

Gene nameinterferon alpha and beta receptor subunit 2
SynonymsIFN-R|IFN-alpha-REC|IFNABR|IFNARB|IMD45
Cytomap

21q22.11

Type of geneprotein-coding
Descriptioninterferon alpha/beta receptor 2IFN-R-2IFN-alpha/beta receptor 2IFNalpha/beta receptor subunit 2human interferon alpha/beta receptorinterferon (alpha, beta and omega) receptor 2interferon alpha binding proteininterferon receptorinterferon-alpha/be
Modification date20210529
UniProtAcc

P48551

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
IFNAR2

GO:0004905

Interferon alpha/beta receptor 2

7665574

IFNAR2

GO:0004905

Interferon alpha/beta receptor 2

7759950

IFNAR2

GO:0035455

Interferon alpha/beta receptor 2

7759950

IFNAR2

GO:0060337

Interferon alpha/beta receptor 2

7665574

IFNAR2

GO:0005887

Interferon alpha/beta receptor 2

7759950


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RNA A-to-I events for IFNAR2

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000159110.18

check button RNA A-to-I editing events in Cancer.
CAediting_1448149(33231766, +), CAediting_1448150(33231767, +), CAediting_1448151(33231797, +), CAediting_1448152(33231821, +), CAediting_1448153(33231822, +), CAediting_1448154(33231842, +), CAediting_1448155(33231859, +), CAediting_1448156(33231871, +), CAediting_1448157(33231876, +), CAediting_1448158(33231881, +), CAediting_1448159(33231883, +), CAediting_1448160(33231907, +), CAediting_1448161(33231919, +), CAediting_1448162(33231922, +), CAediting_1448163(33231945, +), CAediting_1448164(33231949, +), CAediting_1448165(33232001, +), CAediting_1448166(33232014, +), CAediting_1448167(33235677, +), CAediting_1448168(33235710, +), CAediting_1448169(33235715, +), CAediting_1448170(33235739, +), CAediting_1448171(33235805, +), CAediting_1448172(33235811, +), CAediting_1448173(33237322, +), CAediting_1448174(33237405, +), CAediting_1448175(33237414, +), CAediting_1448176(33237420, +), CAediting_1448177(33237455, +), CAediting_1448178(33240559, +), CAediting_1448179(33240565, +), CAediting_1448180(33240566, +), CAediting_1448181(33240614, +), CAediting_1448182(33240623, +), CAediting_1448183(33240624, +), CAediting_1448184(33240626, +), CAediting_1448185(33240628, +), CAediting_1448186(33240639, +), CAediting_1448187(33240645, +), CAediting_1448188(33240654, +), CAediting_1448189(33240668, +), CAediting_1448190(33240680, +), CAediting_1448191(33240683, +), CAediting_1448192(33240685, +), CAediting_1448193(33240687, +), CAediting_1448194(33240705, +), CAediting_1448195(33240735, +), CAediting_1448196(33242477, +), CAediting_1448197(33242494, +), CAediting_1448198(33242504, +), CAediting_1448199(33242555, +), CAediting_1448200(33242582, +), CAediting_1448201(33242583, +), CAediting_1448202(33242586, +), CAediting_1448203(33242612, +), CAediting_1448204(33242639, +), CAediting_1448205(33242654, +), CAediting_1448206(33242713, +), CAediting_1448207(33242716, +), CAediting_1448208(33242809, +), CAediting_1448209(33242821, +), CAediting_1448210(33242858, +), CAediting_1448211(33242889, +), CAediting_1448212(33242893, +), CAediting_1448213(33242915, +), CAediting_1448214(33242918, +), CAediting_1448215(33242928, +), CAediting_1448216(33242963, +), CAediting_1448217(33242972, +), CAediting_1448218(33242978, +), CAediting_1448219(33243048, +), CAediting_1448220(33243051, +), CAediting_1448221(33243183, +), CAediting_1448222(33243187, +), CAediting_1448223(33243200, +), CAediting_1448224(33243209, +), CAediting_1448225(33243212, +), CAediting_1448226(33243224, +), CAediting_1448227(33243240, +), CAediting_1448228(33243249, +), CAediting_1448229(33243258, +), CAediting_1448230(33243264, +), CAediting_1448231(33243267, +), CAediting_1448232(33243269, +), CAediting_1448233(33243273, +), CAediting_1448234(33243312, +), CAediting_1448235(33243330, +), CAediting_1448236(33243345, +), CAediting_1448237(33243357, +), CAediting_1448238(33243359, +), CAediting_1448239(33243370, +), CAediting_1448240(33246332, +), CAediting_1448241(33248765, +), CAediting_1448242(33249089, +), CAediting_1448243(33249184, +), CAediting_1448244(33249213, +), CAediting_1448245(33249223, +), CAediting_1448246(33249224, +), CAediting_1448247(33249250, +), CAediting_1448248(33249264, +), CAediting_1448249(33249265, +), CAediting_1448250(33249269, +), CAediting_1448251(33249276, +), CAediting_1448252(33250556, +), CAediting_1448253(33250638, +), CAediting_1448254(33250677, +), CAediting_1448255(33251849, +), CAediting_1448256(33258162, +), CAediting_1448257(33261111, +), CAediting_1448258(33261117, +), CAediting_1448259(33261130, +), CAediting_1448260(33261163, +), CAediting_1448261(33261166, +), CAediting_1448262(33261194, +), CAediting_1448263(33261298, +), CAediting_1448264(33261299, +), CAediting_1448265(33261597, +), CAediting_1448266(33261679, +), CAediting_1448267(33261694, +), CAediting_1448268(33261729, +), CAediting_1448269(33261737, +), CAediting_1448270(33261747, +), CAediting_1448271(33261761, +), CAediting_1448272(33261765, +), CAediting_1448273(33261769, +), CAediting_1448274(33261785, +), CAediting_1448275(33261801, +), CAediting_1448276(33261817, +), CAediting_1448277(33261871, +), CAediting_1448278(33262163, +), CAediting_1448279(33262189, +), CAediting_1448280(33262226, +), CAediting_1448281(33262228, +), CAediting_1448282(33262258, +), CAediting_1448283(33262285, +), CAediting_1448284(33262313, +), CAediting_1448285(33262314, +), CAediting_1448286(33262538, +), CAediting_1448287(33262539, +), CAediting_1448288(33262559, +), CAediting_1448289(33262576, +), CAediting_1448290(33262586, +), CAediting_1448291(33262609, +), CAediting_1448292(33262615, +), CAediting_1448293(33262620, +), CAediting_1448294(33262631, +), CAediting_1448295(33262646, +), CAediting_1448296(33262647, +), CAediting_1448297(33262649, +), CAediting_1448298(33262662, +), CAediting_1448299(33262663, +), CAediting_1448300(33262675, +), CAediting_1448301(33262688, +),

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RNA editing positional annotations for IFNAR2 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_1448294chr21_33262631_+nonsynonymous SNVENST00000382264.6c.A911Gp.E304GDBN
CAediting_1448294chr21_33262631_+nonsynonymous SNVENST00000404220.6c.A911Gp.E304GDBN
CAediting_1448295chr21_33262646_+nonsynonymous SNVENST00000382264.6c.A926Gp.K309RDPN
CAediting_1448295chr21_33262646_+nonsynonymous SNVENST00000404220.6c.A926Gp.K309RDPN
CAediting_1448297chr21_33262649_+nonsynonymous SNVENST00000382264.6c.A929Gp.Q310RDPN
CAediting_1448297chr21_33262649_+nonsynonymous SNVENST00000404220.6c.A929Gp.Q310RDPN
CAediting_1448299chr21_33262663_+nonsynonymous SNVENST00000382264.6c.A943Gp.S315GDPN
CAediting_1448299chr21_33262663_+nonsynonymous SNVENST00000404220.6c.A943Gp.S315GDPN
CAediting_1448300chr21_33262675_+nonsynonymous SNVENST00000382264.6c.A955Gp.S319GDBN
CAediting_1448300chr21_33262675_+nonsynonymous SNVENST00000404220.6c.A955Gp.S319GDBN

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1448149chr21_33231766_+ncRNA_intronic
CAediting_1448150chr21_33231767_+ncRNA_intronic
CAediting_1448151chr21_33231797_+ncRNA_intronic
CAediting_1448152chr21_33231821_+ncRNA_intronic
CAediting_1448153chr21_33231822_+ncRNA_intronic
CAediting_1448154chr21_33231842_+ncRNA_intronic
CAediting_1448155chr21_33231859_+ncRNA_intronic
CAediting_1448156chr21_33231871_+ncRNA_intronic
CAediting_1448157chr21_33231876_+ncRNA_intronic
CAediting_1448158chr21_33231881_+ncRNA_intronic
CAediting_1448159chr21_33231883_+ncRNA_intronic
CAediting_1448160chr21_33231907_+ncRNA_intronic
CAediting_1448161chr21_33231919_+ncRNA_intronic
CAediting_1448162chr21_33231922_+ncRNA_intronic
CAediting_1448163chr21_33231945_+ncRNA_intronic
CAediting_1448164chr21_33231949_+ncRNA_intronic
CAediting_1448165chr21_33232001_+ncRNA_intronic
CAediting_1448166chr21_33232014_+ncRNA_intronic
CAediting_1448167chr21_33235677_+ncRNA_intronic
CAediting_1448168chr21_33235710_+ncRNA_intronic
CAediting_1448169chr21_33235715_+ncRNA_intronic
CAediting_1448170chr21_33235739_+ncRNA_intronic
CAediting_1448171chr21_33235805_+ncRNA_intronic
CAediting_1448172chr21_33235811_+ncRNA_intronic
CAediting_1448173chr21_33237322_+ncRNA_intronic
CAediting_1448174chr21_33237405_+ncRNA_intronic
CAediting_1448175chr21_33237414_+ncRNA_intronic
CAediting_1448176chr21_33237420_+ncRNA_intronic
CAediting_1448177chr21_33237455_+ncRNA_intronic
CAediting_1448178chr21_33240559_+ncRNA_intronic
CAediting_1448179chr21_33240565_+ncRNA_intronic
CAediting_1448180chr21_33240566_+ncRNA_intronic
CAediting_1448181chr21_33240614_+ncRNA_intronic
CAediting_1448182chr21_33240623_+ncRNA_intronic
CAediting_1448183chr21_33240624_+ncRNA_intronic
CAediting_1448184chr21_33240626_+ncRNA_intronic
CAediting_1448185chr21_33240628_+ncRNA_intronic
CAediting_1448186chr21_33240639_+ncRNA_intronic
CAediting_1448187chr21_33240645_+ncRNA_intronic
CAediting_1448188chr21_33240654_+ncRNA_intronic
CAediting_1448189chr21_33240668_+ncRNA_intronic
CAediting_1448190chr21_33240680_+ncRNA_intronic
CAediting_1448191chr21_33240683_+ncRNA_intronic
CAediting_1448192chr21_33240685_+ncRNA_intronic
CAediting_1448193chr21_33240687_+ncRNA_intronic
CAediting_1448194chr21_33240705_+ncRNA_intronic
CAediting_1448195chr21_33240735_+ncRNA_intronic
CAediting_1448196chr21_33242477_+ncRNA_intronic
CAediting_1448197chr21_33242494_+ncRNA_intronic
CAediting_1448198chr21_33242504_+ncRNA_intronic
CAediting_1448199chr21_33242555_+ncRNA_intronic
CAediting_1448200chr21_33242582_+ncRNA_intronic
CAediting_1448201chr21_33242583_+ncRNA_intronic
CAediting_1448202chr21_33242586_+ncRNA_intronic
CAediting_1448203chr21_33242612_+ncRNA_intronic
CAediting_1448204chr21_33242639_+ncRNA_intronic
CAediting_1448205chr21_33242654_+ncRNA_intronic
CAediting_1448206chr21_33242713_+ncRNA_intronic
CAediting_1448207chr21_33242716_+ncRNA_intronic
CAediting_1448208chr21_33242809_+ncRNA_intronic
CAediting_1448209chr21_33242821_+ncRNA_intronic
CAediting_1448210chr21_33242858_+ncRNA_intronic
CAediting_1448211chr21_33242889_+ncRNA_intronic
CAediting_1448212chr21_33242893_+ncRNA_intronic
CAediting_1448213chr21_33242915_+ncRNA_intronic
CAediting_1448214chr21_33242918_+ncRNA_intronic
CAediting_1448215chr21_33242928_+ncRNA_intronic
CAediting_1448216chr21_33242963_+ncRNA_intronic
CAediting_1448217chr21_33242972_+ncRNA_intronic
CAediting_1448218chr21_33242978_+ncRNA_intronic
CAediting_1448219chr21_33243048_+ncRNA_intronic
CAediting_1448220chr21_33243051_+ncRNA_intronic
CAediting_1448221chr21_33243183_+ncRNA_intronic
CAediting_1448222chr21_33243187_+ncRNA_intronic
CAediting_1448223chr21_33243200_+ncRNA_intronic
CAediting_1448224chr21_33243209_+ncRNA_intronic
CAediting_1448225chr21_33243212_+ncRNA_intronic
CAediting_1448226chr21_33243224_+ncRNA_intronic
CAediting_1448227chr21_33243240_+ncRNA_intronic
CAediting_1448228chr21_33243249_+ncRNA_intronic
CAediting_1448229chr21_33243258_+ncRNA_intronic
CAediting_1448230chr21_33243264_+ncRNA_intronic
CAediting_1448231chr21_33243267_+ncRNA_intronic
CAediting_1448232chr21_33243269_+ncRNA_intronic
CAediting_1448233chr21_33243273_+ncRNA_intronic
CAediting_1448234chr21_33243312_+ncRNA_intronic
CAediting_1448235chr21_33243330_+ncRNA_intronic
CAediting_1448236chr21_33243345_+ncRNA_intronic
CAediting_1448237chr21_33243357_+ncRNA_intronic
CAediting_1448238chr21_33243359_+ncRNA_intronic
CAediting_1448239chr21_33243370_+ncRNA_intronic
CAediting_1448240chr21_33246332_+ncRNA_intronic
CAediting_1448241chr21_33248765_+exonic
CAediting_1448242chr21_33249089_+intronic
CAediting_1448243chr21_33249184_+intronic
CAediting_1448244chr21_33249213_+intronic
CAediting_1448245chr21_33249223_+intronic
CAediting_1448246chr21_33249224_+intronic
CAediting_1448247chr21_33249250_+intronic
CAediting_1448248chr21_33249264_+intronic
CAediting_1448249chr21_33249265_+intronic
CAediting_1448250chr21_33249269_+intronic
CAediting_1448251chr21_33249276_+intronic
CAediting_1448252chr21_33250556_+intronic
CAediting_1448253chr21_33250638_+intronic
CAediting_1448254chr21_33250677_+intronic
CAediting_1448255chr21_33251849_+intronic
CAediting_1448256chr21_33258162_+intronic
CAediting_1448257chr21_33261111_+intronic
CAediting_1448258chr21_33261117_+intronic
CAediting_1448259chr21_33261130_+intronic
CAediting_1448260chr21_33261163_+intronic
CAediting_1448261chr21_33261166_+intronic
CAediting_1448262chr21_33261194_+intronic
CAediting_1448263chr21_33261298_+intronic
CAediting_1448264chr21_33261299_+intronic
CAediting_1448265chr21_33261597_+intronic
CAediting_1448266chr21_33261679_+intronic
CAediting_1448267chr21_33261694_+intronic
CAediting_1448268chr21_33261729_+intronic
CAediting_1448269chr21_33261737_+intronic
CAediting_1448270chr21_33261747_+intronic
CAediting_1448271chr21_33261761_+intronic
CAediting_1448272chr21_33261765_+intronic
CAediting_1448273chr21_33261769_+intronic
CAediting_1448274chr21_33261785_+intronic
CAediting_1448275chr21_33261801_+intronic
CAediting_1448276chr21_33261817_+intronic
CAediting_1448277chr21_33261871_+intronic
CAediting_1448278chr21_33262163_+intronic
CAediting_1448279chr21_33262189_+intronic
CAediting_1448280chr21_33262226_+intronic
CAediting_1448281chr21_33262228_+intronic
CAediting_1448282chr21_33262258_+intronic
CAediting_1448283chr21_33262285_+intronic
CAediting_1448284chr21_33262313_+intronic
CAediting_1448285chr21_33262314_+intronic
CAediting_1448286chr21_33262538_+intronic
CAediting_1448287chr21_33262539_+intronic
CAediting_1448288chr21_33262559_+splicing
CAediting_1448289chr21_33262576_+exonic
CAediting_1448290chr21_33262586_+exonic
CAediting_1448291chr21_33262609_+exonic
CAediting_1448292chr21_33262615_+exonic
CAediting_1448293chr21_33262620_+exonic
CAediting_1448294chr21_33262631_+exonic
CAediting_1448295chr21_33262646_+exonic
CAediting_1448296chr21_33262647_+exonic
CAediting_1448297chr21_33262649_+exonic
CAediting_1448298chr21_33262662_+exonic
CAediting_1448299chr21_33262663_+exonic
CAediting_1448300chr21_33262675_+exonic
CAediting_1448301chr21_33262688_+exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1448149chr21_33231766_+SINEAluAluSz
CAediting_1448150chr21_33231767_+SINEAluAluSz
CAediting_1448151chr21_33231797_+SINEAluAluSz
CAediting_1448152chr21_33231821_+SINEAluAluSz
CAediting_1448153chr21_33231822_+SINEAluAluSz
CAediting_1448154chr21_33231842_+SINEAluAluSz
CAediting_1448155chr21_33231859_+SINEAluAluSz
CAediting_1448156chr21_33231871_+SINEAluAluSz
CAediting_1448157chr21_33231876_+SINEAluAluSz
CAediting_1448158chr21_33231881_+SINEAluAluSz
CAediting_1448159chr21_33231883_+SINEAluAluSz
CAediting_1448160chr21_33231907_+SINEAluAluSz
CAediting_1448161chr21_33231919_+SINEAluAluSz
CAediting_1448162chr21_33231922_+SINEAluAluSz
CAediting_1448163chr21_33231945_+SINEAluAluSz
CAediting_1448164chr21_33231949_+SINEAluAluSz
CAediting_1448165chr21_33232001_+SINEAluAluSz
CAediting_1448166chr21_33232014_+SINEAluAluSz
CAediting_1448167chr21_33235677_+SINEAluAluY
CAediting_1448168chr21_33235710_+SINEAluAluY
CAediting_1448169chr21_33235715_+SINEAluAluY
CAediting_1448170chr21_33235739_+SINEAluAluY
CAediting_1448171chr21_33235805_+SINEAluAluY
CAediting_1448172chr21_33235811_+SINEAluAluY
CAediting_1448173chr21_33237322_+SINEAluAluJb
CAediting_1448174chr21_33237405_+SINEAluAluJb
CAediting_1448175chr21_33237414_+SINEAluAluJb
CAediting_1448176chr21_33237420_+SINEAluAluJb
CAediting_1448177chr21_33237455_+SINEAluAluJb
CAediting_1448178chr21_33240559_+SINEAluAluJb
CAediting_1448179chr21_33240565_+SINEAluAluJb
CAediting_1448180chr21_33240566_+SINEAluAluJb
CAediting_1448181chr21_33240614_+SINEAluAluJb
CAediting_1448182chr21_33240623_+SINEAluAluJb
CAediting_1448183chr21_33240624_+SINEAluAluJb
CAediting_1448184chr21_33240626_+SINEAluAluJb
CAediting_1448185chr21_33240628_+SINEAluAluJb
CAediting_1448186chr21_33240639_+SINEAluAluJb
CAediting_1448187chr21_33240645_+SINEAluAluJb
CAediting_1448188chr21_33240654_+SINEAluAluJb
CAediting_1448189chr21_33240668_+SINEAluAluJb
CAediting_1448190chr21_33240680_+SINEAluAluJb
CAediting_1448191chr21_33240683_+SINEAluAluJb
CAediting_1448192chr21_33240685_+SINEAluAluJb
CAediting_1448193chr21_33240687_+SINEAluAluJb
CAediting_1448194chr21_33240705_+SINEAluAluJb
CAediting_1448195chr21_33240735_+SINEAluAluJb
CAediting_1448196chr21_33242477_+SINEAluAluY
CAediting_1448197chr21_33242494_+SINEAluAluY
CAediting_1448198chr21_33242504_+SINEAluAluY
CAediting_1448199chr21_33242555_+SINEAluAluY
CAediting_1448200chr21_33242582_+SINEAluAluY
CAediting_1448201chr21_33242583_+SINEAluAluY
CAediting_1448202chr21_33242586_+SINEAluAluY
CAediting_1448203chr21_33242612_+SINEAluAluY
CAediting_1448204chr21_33242639_+SINEAluAluY
CAediting_1448205chr21_33242654_+SINEAluAluY
CAediting_1448206chr21_33242713_+SINEAluAluY
CAediting_1448207chr21_33242716_+SINEAluAluY
CAediting_1448208chr21_33242809_+SINEAluAluSx1
CAediting_1448209chr21_33242821_+SINEAluAluSx1
CAediting_1448210chr21_33242858_+SINEAluAluSx1
CAediting_1448211chr21_33242889_+SINEAluAluSx1
CAediting_1448212chr21_33242893_+SINEAluAluSx1
CAediting_1448213chr21_33242915_+SINEAluAluSx1
CAediting_1448214chr21_33242918_+SINEAluAluSx1
CAediting_1448215chr21_33242928_+SINEAluAluSx1
CAediting_1448216chr21_33242963_+SINEAluAluSx1
CAediting_1448217chr21_33242972_+SINEAluAluSx1
CAediting_1448218chr21_33242978_+SINEAluAluSx1
CAediting_1448219chr21_33243048_+SINEAluAluSx1
CAediting_1448220chr21_33243051_+SINEAluAluSx1
CAediting_1448221chr21_33243183_+SINEAluAluSx3
CAediting_1448222chr21_33243187_+SINEAluAluSx3
CAediting_1448223chr21_33243200_+SINEAluAluSx3
CAediting_1448224chr21_33243209_+SINEAluAluSx3
CAediting_1448225chr21_33243212_+SINEAluAluSx3
CAediting_1448226chr21_33243224_+SINEAluAluSx3
CAediting_1448227chr21_33243240_+SINEAluAluSx3
CAediting_1448228chr21_33243249_+SINEAluAluSx3
CAediting_1448229chr21_33243258_+SINEAluAluSx3
CAediting_1448230chr21_33243264_+SINEAluAluSx3
CAediting_1448231chr21_33243267_+SINEAluAluSx3
CAediting_1448232chr21_33243269_+SINEAluAluSx3
CAediting_1448233chr21_33243273_+SINEAluAluSx3
CAediting_1448234chr21_33243312_+SINEAluAluSx3
CAediting_1448235chr21_33243330_+SINEAluAluSx3
CAediting_1448236chr21_33243345_+SINEAluAluSx3
CAediting_1448237chr21_33243357_+SINEAluAluSx3
CAediting_1448238chr21_33243359_+SINEAluAluSx3
CAediting_1448239chr21_33243370_+SINEAluAluSx3
CAediting_1448240chr21_33246332_+SINEAluAluY
CAediting_1448242chr21_33249089_+SINEAluAluSx1
CAediting_1448243chr21_33249184_+SINEAluAluSx1
CAediting_1448244chr21_33249213_+SINEAluAluSx1
CAediting_1448245chr21_33249223_+SINEAluAluSx1
CAediting_1448246chr21_33249224_+SINEAluAluSx1
CAediting_1448247chr21_33249250_+SINEAluAluSx1
CAediting_1448248chr21_33249264_+SINEAluAluSx1
CAediting_1448249chr21_33249265_+SINEAluAluSx1
CAediting_1448250chr21_33249269_+SINEAluAluSx1
CAediting_1448251chr21_33249276_+SINEAluAluSx1
CAediting_1448252chr21_33250556_+SINEAluAluSq2
CAediting_1448253chr21_33250638_+SINEAluAluSq2
CAediting_1448254chr21_33250677_+SINEAluAluSq2
CAediting_1448255chr21_33251849_+SINEAluAluSx1
CAediting_1448256chr21_33258162_+SINEAluAluSx
CAediting_1448257chr21_33261111_+SINEAluAluSz6
CAediting_1448258chr21_33261117_+SINEAluAluSz6
CAediting_1448259chr21_33261130_+SINEAluAluSz6
CAediting_1448260chr21_33261163_+SINEAluAluSz6
CAediting_1448261chr21_33261166_+SINEAluAluSz6
CAediting_1448262chr21_33261194_+SINEAluAluSz6
CAediting_1448263chr21_33261298_+SINEAluAluSz6
CAediting_1448264chr21_33261299_+SINEAluAluSz6
CAediting_1448265chr21_33261597_+SINEAluAluJb
CAediting_1448266chr21_33261679_+SINEAluAluJb
CAediting_1448267chr21_33261694_+SINEAluAluJb
CAediting_1448268chr21_33261729_+SINEAluAluJb
CAediting_1448269chr21_33261737_+SINEAluAluJb
CAediting_1448270chr21_33261747_+SINEAluAluJb
CAediting_1448271chr21_33261761_+SINEAluAluJb
CAediting_1448272chr21_33261765_+SINEAluAluJb
CAediting_1448273chr21_33261769_+SINEAluAluJb
CAediting_1448274chr21_33261785_+SINEAluAluJb
CAediting_1448275chr21_33261801_+SINEAluAluJb
CAediting_1448276chr21_33261817_+SINEAluAluJb
CAediting_1448277chr21_33261871_+SINEAluAluJb
CAediting_1448278chr21_33262163_+SINEAluAluSg7
CAediting_1448279chr21_33262189_+SINEAluAluSg7
CAediting_1448280chr21_33262226_+SINEAluAluSg7
CAediting_1448281chr21_33262228_+SINEAluAluSg7
CAediting_1448282chr21_33262258_+SINEAluAluSg7
CAediting_1448283chr21_33262285_+SINEAluAluSg7
CAediting_1448284chr21_33262313_+SINEAluAluSg7
CAediting_1448285chr21_33262314_+SINEAluAluSg7
CAediting_1448288chr21_33262559_+SINEAluAluJr
CAediting_1448289chr21_33262576_+SINEAluAluJr
CAediting_1448290chr21_33262586_+SINEAluAluJr
CAediting_1448291chr21_33262609_+SINEAluAluJr
CAediting_1448292chr21_33262615_+SINEAluAluJr
CAediting_1448293chr21_33262620_+SINEAluAluJr
CAediting_1448294chr21_33262631_+SINEAluAluJr
CAediting_1448295chr21_33262646_+SINEAluAluJr
CAediting_1448296chr21_33262647_+SINEAluAluJr
CAediting_1448297chr21_33262649_+SINEAluAluJr
CAediting_1448298chr21_33262662_+SINEAluAluJr
CAediting_1448299chr21_33262663_+SINEAluAluJr
CAediting_1448300chr21_33262675_+SINEAluAluJr
CAediting_1448301chr21_33262688_+SINEAluAluJr

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RNA A-to-I editing events in the alternative splicing sites for IFNAR2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000159110.18.IFNAR2.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000159110.18.IFNAR2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for IFNAR2

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for IFNAR2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for IFNAR2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1448290chr21_33262586_+ENSG00000159110.18ENST00000417007hsa-miR-508-5p33262580332625867mer-m83326256533262587140.00-21.74
CAediting_1448290chr21_33262586_+ENSG00000159110.18ENST00000417007hsa-miR-766-3p33262579332625857mer-m83326256533262586150.00-23.51
CAediting_1448290chr21_33262586_+ENSG00000159110.18ENST00000417007hsa-miR-770333262583332625897mer-m83326256833262590163.00-25.83
CAediting_1448299chr21_33262663_+ENSG00000159110.18ENST00000417007hsa-miR-3135a33262658332626647mer-m83326264233262665159.00-25.60
CAediting_1448294chr21_33262631_+ENSG00000159110.18ENST00000417007hsa-miR-3180-5p33262626332626327mer-m83326260933262633145.00-13.36
CAediting_1448294chr21_33262631_+ENSG00000159110.18ENST00000417007hsa-miR-3180-5p33262626332626327mer-m83326260933262633145.00-13.36
CAediting_1448294chr21_33262631_+ENSG00000159110.18ENST00000417007hsa-miR-3180-5p33262626332626327mer-m83326260933262633145.00-13.36
CAediting_1448295chr21_33262646_+ENSG00000159110.18ENST00000417007hsa-miR-3120-5p33262643332626497mer-m83326262933262650149.00-15.93
CAediting_1448295chr21_33262646_+ENSG00000159110.18ENST00000417007hsa-miR-430333262640332626467mer-m83326263133262647162.00-19.93
CAediting_1448297chr21_33262649_+ENSG00000159110.18ENST00000417007hsa-miR-570733262642332626487mer-m83326262833262649144.00-13.87
CAediting_1448298chr21_33262662_+ENSG00000159110.18ENST00000417007hsa-miR-3934-3p33262658332626647mer-m83326264433262665163.00-20.39
CAediting_1448298chr21_33262662_+ENSG00000159110.18ENST00000417007hsa-miR-451433262655332626628mer-1a3326264533262662151.00-20.74
CAediting_1448298chr21_33262662_+ENSG00000159110.18ENST00000417007hsa-miR-469233262655332626628mer-1a3326263933262662151.00-18.16
CAediting_1448300chr21_33262675_+ENSG00000159110.18ENST00000417007hsa-miR-425233262670332626767mer-m83326265933262677151.00-17.27
CAediting_1448300chr21_33262675_+ENSG00000159110.18ENST00000417007hsa-miR-4691-3p33262672332626787mer-m83326265733262679144.00-22.14

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1448292chr21_33262615_+ENSG00000159110.18ENST00000417007hsa-miR-33a-5p33262614332626196mer3326260033262620150-22.26
CAediting_1448293chr21_33262620_+ENSG00000159110.18ENST00000417007hsa-miR-33a-5p33262614332626196mer3326260033262620150-22.26
CAediting_1448292chr21_33262615_+ENSG00000159110.18ENST00000417007hsa-miR-33b-5p33262614332626196mer3326260133262620142-18.59
CAediting_1448293chr21_33262620_+ENSG00000159110.18ENST00000417007hsa-miR-33b-5p33262614332626196mer3326260133262620142-18.59
CAediting_1448295chr21_33262646_+ENSG00000159110.18ENST00000417007hsa-miR-452-5p33262644332626507mer-m83326262833262651151-14.26
CAediting_1448296chr21_33262647_+ENSG00000159110.18ENST00000417007hsa-miR-452-5p33262644332626507mer-m83326262833262651151-14.26
CAediting_1448297chr21_33262649_+ENSG00000159110.18ENST00000417007hsa-miR-452-5p33262644332626507mer-m83326262833262651151-14.26
CAediting_1448293chr21_33262620_+ENSG00000159110.18ENST00000417007hsa-miR-4671-3p33262616332626227mer-m83326260333262623153-12.82
CAediting_1448295chr21_33262646_+ENSG00000159110.18ENST00000417007hsa-miR-4676-3p33262644332626507mer-m83326263033262651153-9.59
CAediting_1448296chr21_33262647_+ENSG00000159110.18ENST00000417007hsa-miR-4676-3p33262644332626507mer-m83326263033262651153-9.59
CAediting_1448297chr21_33262649_+ENSG00000159110.18ENST00000417007hsa-miR-4676-3p33262644332626507mer-m83326263033262651153-9.59
CAediting_1448291chr21_33262609_+ENSG00000159110.18ENST00000417007hsa-miR-4793-3p33262604332626096mer3326258533262610146-24.24
CAediting_1448291chr21_33262609_+ENSG00000159110.18ENST00000417007hsa-miR-500a-3p33262602332626087mer-m83326258833262609152-18.34
CAediting_1448300chr21_33262675_+ENSG00000159110.18ENST00000417007hsa-miR-569033262672332626787mer-m83326265933262679145-16.35
CAediting_1448295chr21_33262646_+ENSG00000159110.18ENST00000417007hsa-miR-892c-3p33262644332626507mer-m83326262933262651150-12.65
CAediting_1448296chr21_33262647_+ENSG00000159110.18ENST00000417007hsa-miR-892c-3p33262644332626507mer-m83326262933262651150-12.65
CAediting_1448297chr21_33262649_+ENSG00000159110.18ENST00000417007hsa-miR-892c-3p33262644332626507mer-m83326262933262651150-12.65
CAediting_1448289chr21_33262576_+ENSG00000159110.18ENST00000417007hsa-miR-93833262574332625807mer-m83326256233262581145-17.33

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000159110.18ENST00000404220hsa-miR-605-3p33264100332641067mer-m83326408633264107140-16.47
CAediting_980496chr14_31014685_-ENSG00000159110.18ENST00000404220hsa-miR-624-3p33264980332649867mer-m83326496833264987155-17.99
CAediting_748296chr10_51299626_+ENSG00000159110.18ENST00000342101hsa-miR-605-3p33264100332641067mer-m83326408633264107140-16.47
CAediting_1054808chr15_66496985_-ENSG00000159110.18ENST00000404220hsa-miR-451233265330332653367mer-m83326531633265337143-13.73
CAediting_1229413chr17_67471544_+ENSG00000159110.18ENST00000404220hsa-miR-548aa33265308332653147mer-m83326529133265315140-14.71
CAediting_228905chr2_188297554_+ENSG00000159110.18ENST00000404220hsa-miR-561-3p33263232332632387mer-m83326321633263239170-26.18
CAediting_396018chr5_1062918_-ENSG00000159110.18ENST00000404220hsa-miR-463533264088332640947mer-m83326407533264095162-21.04
CAediting_396018chr5_1062918_-ENSG00000159110.18ENST00000404220hsa-miR-463533265298332653058mer-1a3326528533265305140-15.11
CAediting_442554chr5_154685830_+ENSG00000159110.18ENST00000404220hsa-miR-130333265162332651687mer-m83326514833265169140-14.72
CAediting_442554chr5_154685830_+ENSG00000159110.18ENST00000404220hsa-miR-130333263592332635987mer-m83326358133263599143-17.11
CAediting_228905chr2_188297554_+ENSG00000159110.18ENST00000342101hsa-miR-561-3p33263232332632387mer-m83326321633263239170-26.18
CAediting_396018chr5_1062918_-ENSG00000159110.18ENST00000342101hsa-miR-463533264088332640947mer-m83326407533264095162-21.04
CAediting_442554chr5_154685830_+ENSG00000159110.18ENST00000342101hsa-miR-130333263592332635987mer-m83326358133263599143-17.11
CAediting_1229414chr17_67471546_+ENSG00000159110.18ENST00000382238hsa-miR-548aa33260650332606567mer-m83326063333260657142-12.28
CAediting_1229414chr17_67471546_+ENSG00000159110.18ENST00000417007hsa-miR-548aa33260650332606567mer-m83326063333260657142-12.28
CAediting_468389chr6_31355314_-ENSG00000159110.18ENST00000404220hsa-miR-6891-5p33264103332641108mer-1a3326409133264110154-22.93
CAediting_468389chr6_31355314_-ENSG00000159110.18ENST00000342101hsa-miR-6891-5p33264103332641108mer-1a3326409133264110154-22.93

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1054808chr15_66496985_-ENSG00000159110.18ENST00000404220hsa-miR-451233264289332642946mer3326427533264295146-26.44
CAediting_396018chr5_1062918_-ENSG00000159110.18ENST00000404220hsa-miR-463533264541332645488mer-1a3326452833264548141-11.33
CAediting_748296chr10_51299626_+ENSG00000159110.18ENST00000404220hsa-miR-605-3p33265501332655077mer-m83326548533265508153-17.65
CAediting_980496chr14_31014685_-ENSG00000159110.18ENST00000404220hsa-miR-624-3p33264389332643957mer-m83326437933264396147-12.41
CAediting_980496chr14_31014685_-ENSG00000159110.18ENST00000342101hsa-miR-624-3p33264389332643957mer-m83326437933264396147-12.41

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for IFNAR2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for IFNAR2

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LAMLCAediting_1448150chr21_33231767_+....0.04929452218291750.219190892280027
LAMLCAediting_1448153chr21_33231822_+..0.04645892560501860.209309676593083..

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Relation with cancer stages for IFNAR2

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for IFNAR2

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LAMLCAediting_1448149chr21_33231766_+0.01031770054748670.00101971113.713

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RelatedDrugs for IFNAR2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
IFNAR2P48551DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 2 BiotechDrugapproved
IFNAR2P48551DB00068Interferon beta-1bInterferon alpha/beta receptor 2 BiotechDrugapproved
IFNAR2P48551DB00105Interferon alfa-2bInterferon alpha/beta receptor 2 BiotechDrugapproved
IFNAR2P48551DB06152NylidrinInterferon alpha/beta receptor 2 SmallMoleculeDrugapproved
IFNAR2P48551DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 2 BiotechDrugapproved|investigational
IFNAR2P48551DB00011Interferon alfa-n1Interferon alpha/beta receptor 2 BiotechDrugapproved|investigational
IFNAR2P48551DB00018Interferon alfa-n3Interferon alpha/beta receptor 2 BiotechDrugapproved|investigational
IFNAR2P48551DB00034Interferon alfa-2a, RecombinantInterferon alpha/beta receptor 2 BiotechDrugapproved|investigational
IFNAR2P48551DB00060Interferon beta-1aInterferon alpha/beta receptor 2 BiotechDrugapproved|investigational
IFNAR2P48551DB00069Interferon alfacon-1Interferon alpha/beta receptor 2 BiotechDrugapproved|investigational

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RelatedDiseases for IFNAR2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
IFNAR2C4225252IMMUNODEFICIENCY 451CTD_human;GENOMICS_ENGLAND;ORPHANET
IFNAR2C4225260IMMUNODEFICIENCY 441ORPHANET