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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: BIRC3 (CAeditome ID:330)

Gene summary for BIRC3

check button Gene summary
Gene informationGene symbol

BIRC3

Gene ID

330

Gene namebaculoviral IAP repeat containing 3
SynonymsAIP1|API2|CIAP2|HAIP1|HIAP1|IAP-1|MALT2|MIHC|RNF49|c-IAP2
Cytomap

11q22.2

Type of geneprotein-coding
Descriptionbaculoviral IAP repeat-containing protein 3IAP homolog CRING finger protein 49RING-type E3 ubiquitin transferase BIRC3TNFR2-TRAF signaling complex proteinTNFR2-TRAF-signaling complex protein 1apoptosis inhibitor 2cellular inhibitor of apoptosis 2i
Modification date20210518
UniProtAcc

Q13489

Context- 33413657(BIRC3 and BIRC5: multi-faceted inhibitors in cancer)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
BIRC3

GO:0004842

Baculoviral IAP repeat-containing protein 3

16395405

BIRC3

GO:0004842

Baculoviral IAP repeat-containing protein 3

21931591

BIRC3

GO:0031398

Baculoviral IAP repeat-containing protein 3

21931591

BIRC3

GO:0005634

Baculoviral IAP repeat-containing protein 3

15665297

BIRC3

GO:0005634

Baculoviral IAP repeat-containing protein 3

16123224

BIRC3

GO:0005654

Baculoviral IAP repeat-containing protein 3

0000052

BIRC3

GO:0005737

Baculoviral IAP repeat-containing protein 3

15665297

BIRC3

GO:0005737

Baculoviral IAP repeat-containing protein 3

16123224

BIRC3

GO:0005829

Baculoviral IAP repeat-containing protein 3

0000052


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RNA A-to-I events for BIRC3

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000023445.12

check button RNA A-to-I editing events in Cancer.
CAediting_848676(102319999, +), CAediting_848677(102326727, +), CAediting_848678(102326782, +), CAediting_848679(102326788, +), CAediting_848680(102326807, +), CAediting_848681(102326811, +), CAediting_848682(102326812, +), CAediting_848683(102326838, +), CAediting_848684(102326848, +), CAediting_848685(102326850, +), CAediting_848686(102326897, +), CAediting_848687(102327461, +), CAediting_848688(102327469, +), CAediting_848689(102327480, +), CAediting_848690(102327487, +), CAediting_848691(102327488, +), CAediting_848692(102327493, +), CAediting_848693(102327529, +), CAediting_848694(102327549, +), CAediting_848695(102327555, +), CAediting_848696(102327561, +), CAediting_848697(102327572, +), CAediting_848698(102327579, +), CAediting_848699(102331676, +), CAediting_848700(102331684, +), CAediting_848701(102331714, +), CAediting_848702(102331719, +), CAediting_848703(102331725, +), CAediting_848704(102331745, +), CAediting_848705(102331748, +), CAediting_848706(102331749, +), CAediting_848707(102331780, +), CAediting_848708(102331782, +), CAediting_848709(102331793, +), CAediting_848710(102331821, +), CAediting_848711(102331824, +), CAediting_848712(102331829, +), CAediting_848713(102331841, +), CAediting_848714(102331861, +), CAediting_848715(102331862, +), CAediting_848716(102331863, +), CAediting_848717(102331875, +), CAediting_848718(102331876, +), CAediting_848719(102331903, +), CAediting_848720(102333301, +), CAediting_848721(102333307, +), CAediting_848722(102333334, +), CAediting_848723(102333338, +), CAediting_848724(102333347, +), CAediting_848725(102333348, +), CAediting_848726(102333353, +), CAediting_848727(102333361, +), CAediting_848728(102333362, +), CAediting_848729(102333364, +), CAediting_848730(102333367, +), CAediting_848731(102333381, +), CAediting_848732(102333406, +), CAediting_848733(102333408, +), CAediting_848734(102333411, +), CAediting_848735(102333413, +), CAediting_848736(102333417, +), CAediting_848737(102333420, +), CAediting_848738(102333459, +), CAediting_848739(102333481, +), CAediting_848740(102333486, +), CAediting_848741(102333501, +), CAediting_848742(102333508, +), CAediting_848743(102333571, +), CAediting_848744(102333586, +), CAediting_848745(102333590, +), CAediting_848746(102333592, +), CAediting_848747(102333654, +), CAediting_848748(102333660, +), CAediting_848749(102333667, +), CAediting_848750(102333691, +), CAediting_848751(102333696, +), CAediting_848752(102333703, +), CAediting_848753(102333872, +), CAediting_848754(102334970, +), CAediting_848755(102335021, +), CAediting_848756(102335063, +), CAediting_848757(102335095, +), CAediting_848758(102335128, +), CAediting_848759(102335135, +), CAediting_848760(102335150, +), CAediting_848761(102335151, +), CAediting_848762(102335152, +), CAediting_848763(102335170, +), CAediting_848764(102335666, +), CAediting_848765(102335667, +), CAediting_848766(102335716, +), CAediting_848767(102335742, +), CAediting_848768(102335743, +), CAediting_848769(102335746, +), CAediting_848770(102336539, +),

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RNA editing positional annotations for BIRC3 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_848683chr11_102326838_+nonsynonymous SNVENST00000527309.1c.A352Gp.S118GD.N
CAediting_848684chr11_102326848_+nonsynonymous SNVENST00000527309.1c.A362Gp.Y121CD.N

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_848676chr11_102319999_+ncRNA_exonic
CAediting_848677chr11_102326727_+splicing
CAediting_848678chr11_102326782_+exonic
CAediting_848679chr11_102326788_+exonic
CAediting_848680chr11_102326807_+exonic
CAediting_848681chr11_102326811_+exonic
CAediting_848682chr11_102326812_+exonic
CAediting_848683chr11_102326838_+exonic
CAediting_848684chr11_102326848_+exonic
CAediting_848685chr11_102326850_+exonic
CAediting_848686chr11_102326897_+intronic
CAediting_848687chr11_102327461_+intronic
CAediting_848688chr11_102327469_+intronic
CAediting_848689chr11_102327480_+intronic
CAediting_848690chr11_102327487_+intronic
CAediting_848691chr11_102327488_+intronic
CAediting_848692chr11_102327493_+intronic
CAediting_848693chr11_102327529_+intronic
CAediting_848694chr11_102327549_+intronic
CAediting_848695chr11_102327555_+intronic
CAediting_848696chr11_102327561_+intronic
CAediting_848697chr11_102327572_+intronic
CAediting_848698chr11_102327579_+intronic
CAediting_848699chr11_102331676_+intronic
CAediting_848700chr11_102331684_+intronic
CAediting_848701chr11_102331714_+intronic
CAediting_848702chr11_102331719_+intronic
CAediting_848703chr11_102331725_+intronic
CAediting_848704chr11_102331745_+intronic
CAediting_848705chr11_102331748_+intronic
CAediting_848706chr11_102331749_+intronic
CAediting_848707chr11_102331780_+intronic
CAediting_848708chr11_102331782_+intronic
CAediting_848709chr11_102331793_+intronic
CAediting_848710chr11_102331821_+intronic
CAediting_848711chr11_102331824_+intronic
CAediting_848712chr11_102331829_+intronic
CAediting_848713chr11_102331841_+intronic
CAediting_848714chr11_102331861_+intronic
CAediting_848715chr11_102331862_+intronic
CAediting_848716chr11_102331863_+intronic
CAediting_848717chr11_102331875_+intronic
CAediting_848718chr11_102331876_+intronic
CAediting_848719chr11_102331903_+intronic
CAediting_848720chr11_102333301_+intronic
CAediting_848721chr11_102333307_+intronic
CAediting_848722chr11_102333334_+intronic
CAediting_848723chr11_102333338_+intronic
CAediting_848724chr11_102333347_+intronic
CAediting_848725chr11_102333348_+intronic
CAediting_848726chr11_102333353_+intronic
CAediting_848727chr11_102333361_+intronic
CAediting_848728chr11_102333362_+intronic
CAediting_848729chr11_102333364_+intronic
CAediting_848730chr11_102333367_+intronic
CAediting_848731chr11_102333381_+intronic
CAediting_848732chr11_102333406_+intronic
CAediting_848733chr11_102333408_+intronic
CAediting_848734chr11_102333411_+intronic
CAediting_848735chr11_102333413_+intronic
CAediting_848736chr11_102333417_+intronic
CAediting_848737chr11_102333420_+intronic
CAediting_848738chr11_102333459_+intronic
CAediting_848739chr11_102333481_+intronic
CAediting_848740chr11_102333486_+intronic
CAediting_848741chr11_102333501_+intronic
CAediting_848742chr11_102333508_+intronic
CAediting_848743chr11_102333571_+intronic
CAediting_848744chr11_102333586_+intronic
CAediting_848745chr11_102333590_+intronic
CAediting_848746chr11_102333592_+intronic
CAediting_848747chr11_102333654_+intronic
CAediting_848748chr11_102333660_+intronic
CAediting_848749chr11_102333667_+intronic
CAediting_848750chr11_102333691_+intronic
CAediting_848751chr11_102333696_+intronic
CAediting_848752chr11_102333703_+intronic
CAediting_848753chr11_102333872_+intronic
CAediting_848754chr11_102334970_+intronic
CAediting_848755chr11_102335021_+intronic
CAediting_848756chr11_102335063_+intronic
CAediting_848757chr11_102335095_+intronic
CAediting_848758chr11_102335128_+intronic
CAediting_848759chr11_102335135_+intronic
CAediting_848760chr11_102335150_+intronic
CAediting_848761chr11_102335151_+intronic
CAediting_848762chr11_102335152_+intronic
CAediting_848763chr11_102335170_+intronic
CAediting_848764chr11_102335666_+intronic
CAediting_848765chr11_102335667_+intronic
CAediting_848766chr11_102335716_+intronic
CAediting_848767chr11_102335742_+intronic
CAediting_848768chr11_102335743_+intronic
CAediting_848769chr11_102335746_+intronic
CAediting_848770chr11_102336539_+ncRNA_exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_848676chr11_102319999_+SINEAluAluSz
CAediting_848677chr11_102326727_+SINEAluAluSx
CAediting_848678chr11_102326782_+SINEAluAluSx
CAediting_848679chr11_102326788_+SINEAluAluSx
CAediting_848680chr11_102326807_+SINEAluAluSx
CAediting_848681chr11_102326811_+SINEAluAluSx
CAediting_848682chr11_102326812_+SINEAluAluSx
CAediting_848683chr11_102326838_+SINEAluAluSx
CAediting_848684chr11_102326848_+SINEAluAluSx
CAediting_848685chr11_102326850_+SINEAluAluSx
CAediting_848686chr11_102326897_+SINEAluAluSx
CAediting_848687chr11_102327461_+SINEAluAluSz6
CAediting_848688chr11_102327469_+SINEAluAluSz6
CAediting_848689chr11_102327480_+SINEAluAluSz6
CAediting_848690chr11_102327487_+SINEAluAluSz6
CAediting_848691chr11_102327488_+SINEAluAluSz6
CAediting_848692chr11_102327493_+SINEAluAluSz6
CAediting_848693chr11_102327529_+SINEAluAluSz6
CAediting_848694chr11_102327549_+SINEAluAluSz6
CAediting_848695chr11_102327555_+SINEAluAluSz6
CAediting_848696chr11_102327561_+SINEAluAluSz6
CAediting_848697chr11_102327572_+SINEAluAluSz6
CAediting_848698chr11_102327579_+SINEAluAluSz6
CAediting_848699chr11_102331676_+SINEAluAluSx1
CAediting_848700chr11_102331684_+SINEAluAluSx1
CAediting_848701chr11_102331714_+SINEAluAluSx1
CAediting_848702chr11_102331719_+SINEAluAluSx1
CAediting_848703chr11_102331725_+SINEAluAluSx1
CAediting_848704chr11_102331745_+SINEAluAluSx1
CAediting_848705chr11_102331748_+SINEAluAluSx1
CAediting_848706chr11_102331749_+SINEAluAluSx1
CAediting_848707chr11_102331780_+SINEAluAluSx1
CAediting_848708chr11_102331782_+SINEAluAluSx1
CAediting_848709chr11_102331793_+SINEAluAluSx1
CAediting_848710chr11_102331821_+SINEAluAluSx1
CAediting_848711chr11_102331824_+SINEAluAluSx1
CAediting_848712chr11_102331829_+SINEAluAluSx1
CAediting_848713chr11_102331841_+SINEAluAluSx1
CAediting_848714chr11_102331861_+SINEAluAluSx1
CAediting_848715chr11_102331862_+SINEAluAluSx1
CAediting_848716chr11_102331863_+SINEAluAluSx1
CAediting_848717chr11_102331875_+SINEAluAluSx1
CAediting_848718chr11_102331876_+SINEAluAluSx1
CAediting_848719chr11_102331903_+SINEAluAluSx1
CAediting_848720chr11_102333301_+SINEAluAluJr
CAediting_848721chr11_102333307_+SINEAluAluJr
CAediting_848722chr11_102333334_+SINEAluAluJr
CAediting_848723chr11_102333338_+SINEAluAluJr
CAediting_848724chr11_102333347_+SINEAluAluJr
CAediting_848725chr11_102333348_+SINEAluAluJr
CAediting_848726chr11_102333353_+SINEAluAluJr
CAediting_848727chr11_102333361_+SINEAluAluJr
CAediting_848728chr11_102333362_+SINEAluAluJr
CAediting_848729chr11_102333364_+SINEAluAluJr
CAediting_848730chr11_102333367_+SINEAluAluJr
CAediting_848731chr11_102333381_+SINEAluAluJr
CAediting_848732chr11_102333406_+SINEAluAluJr
CAediting_848733chr11_102333408_+SINEAluAluJr
CAediting_848734chr11_102333411_+SINEAluAluJr
CAediting_848735chr11_102333413_+SINEAluAluJr
CAediting_848736chr11_102333417_+SINEAluAluJr
CAediting_848737chr11_102333420_+SINEAluAluJr
CAediting_848738chr11_102333459_+SINEAluAluJr
CAediting_848739chr11_102333481_+SINEAluAluJr
CAediting_848740chr11_102333486_+SINEAluAluJr
CAediting_848741chr11_102333501_+SINEAluAluJr
CAediting_848742chr11_102333508_+SINEAluAluJr
CAediting_848743chr11_102333571_+SINEAluAluJr
CAediting_848744chr11_102333586_+SINEAluAluJr
CAediting_848745chr11_102333590_+SINEAluAluJr
CAediting_848746chr11_102333592_+SINEAluAluJr
CAediting_848747chr11_102333654_+SINEAluAluSz6
CAediting_848748chr11_102333660_+SINEAluAluSz6
CAediting_848749chr11_102333667_+SINEAluAluSz6
CAediting_848750chr11_102333691_+SINEAluAluSz6
CAediting_848751chr11_102333696_+SINEAluAluSz6
CAediting_848752chr11_102333703_+SINEAluAluSz6
CAediting_848753chr11_102333872_+SINEAluAluJo
CAediting_848754chr11_102334970_+SINEAluAluSz6
CAediting_848755chr11_102335021_+SINEAluAluSz6
CAediting_848756chr11_102335063_+SINEAluAluSz6
CAediting_848757chr11_102335095_+SINEAluAluSz6
CAediting_848758chr11_102335128_+SINEAluAluSz6
CAediting_848759chr11_102335135_+SINEAluAluSz6
CAediting_848760chr11_102335150_+SINEAluAluSz6
CAediting_848761chr11_102335151_+SINEAluAluSz6
CAediting_848762chr11_102335152_+SINEAluAluSz6
CAediting_848763chr11_102335170_+SINEAluAluSz6
CAediting_848764chr11_102335666_+SINEAluFLAM_A
CAediting_848765chr11_102335667_+SINEAluFLAM_A
CAediting_848766chr11_102335716_+SINEAluFLAM_A
CAediting_848767chr11_102335742_+SINEAluFLAM_A
CAediting_848768chr11_102335743_+SINEAluFLAM_A
CAediting_848769chr11_102335746_+SINEAluFLAM_A
CAediting_848770chr11_102336539_+SINEAluAluJo

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RNA A-to-I editing events in the alternative splicing sites for BIRC3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_848677chr11_102326727_+102326708:1023267303SS0+1iTTTTTCCTCTTTTCTTTTGAGAT-2.82TTTTTCCTCTTTTCTTTTGGGAT5.93
ESCAediting_848685chr11_102326850_+102326849:1023268575SS2+0iCAGGTGCAC4.29CGGGTGCAC-0.67

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000023445.12.BIRC3.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000023445.12.BIRC3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for BIRC3

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for BIRC3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for BIRC3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_393chr1_1167164_+ENSG00000023445.12ENST00000615299hsa-miR-200b-3p1023386291023386357mer-m8102338615102338636151-13.97
CAediting_393chr1_1167164_+ENSG00000023445.12ENST00000615299hsa-miR-200b-3p1023373561023373638mer-1a102337344102337363145-12.57
CAediting_688081chr9_63819627_+ENSG00000023445.12ENST00000615299hsa-miR-4477b1023393451023393517mer-m8102339330102339352155-12.3
CAediting_393chr1_1167164_+ENSG00000023445.12ENST00000532808hsa-miR-200b-3p1023386291023386357mer-m8102338615102338636151-13.97
CAediting_393chr1_1167164_+ENSG00000023445.12ENST00000532808hsa-miR-200b-3p1023373561023373638mer-1a102337344102337363145-12.57
CAediting_688081chr9_63819627_+ENSG00000023445.12ENST00000532808hsa-miR-4477b1023393451023393517mer-m8102339330102339352155-12.3
CAediting_1229413chr17_67471544_+ENSG00000023445.12ENST00000615299hsa-miR-548aa1023371771023371837mer-m8102337161102337184156-9.9
CAediting_1160181chr17_7017644_-ENSG00000023445.12ENST00000615299hsa-miR-195-3p1023372151023372217mer-m8102337201102337222150-9.4
CAediting_1368054chr19_46709310_-ENSG00000023445.12ENST00000615299hsa-miR-320e1023387261023387327mer-m8102338716102338733143-16.4
CAediting_1399425chr20_1392958_-ENSG00000023445.12ENST00000615299hsa-miR-6869-5p1023390871023390937mer-m8102339074102339094149-21.55
CAediting_573001chr7_92204086_-ENSG00000023445.12ENST00000615299hsa-miR-1285-5p1023375471023375526mer102337533102337553151-34.64
CAediting_1229413chr17_67471544_+ENSG00000023445.12ENST00000532808hsa-miR-548aa1023371771023371837mer-m8102337161102337184156-9.9
CAediting_1160181chr17_7017644_-ENSG00000023445.12ENST00000532808hsa-miR-195-3p1023372151023372217mer-m8102337201102337222150-9.4
CAediting_1368054chr19_46709310_-ENSG00000023445.12ENST00000532808hsa-miR-320e1023387261023387327mer-m8102338716102338733143-16.4
CAediting_1399425chr20_1392958_-ENSG00000023445.12ENST00000532808hsa-miR-6869-5p1023390871023390937mer-m8102339074102339094149-21.55
CAediting_573001chr7_92204086_-ENSG00000023445.12ENST00000532808hsa-miR-1285-5p1023375471023375526mer102337533102337553151-34.64

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1160181chr17_7017644_-ENSG00000023445.12ENST00000615299hsa-miR-195-3p1023378131023378208mer-1a102337799102337820149-9.24
CAediting_688081chr9_63819627_+ENSG00000023445.12ENST00000615299hsa-miR-4477b1023371821023371898mer-1a102337170102337189145-8.44
CAediting_117844chr1_162342605_+ENSG00000023445.12ENST00000615299hsa-miR-556-3p1023392971023393048mer-1a102339283102339304152-9.5
CAediting_228905chr2_188297554_+ENSG00000023445.12ENST00000615299hsa-miR-561-3p1023389071023389137mer-m8102338896102338914143-12.05
CAediting_228905chr2_188297554_+ENSG00000023445.12ENST00000615299hsa-miR-561-3p1023392731023392797mer-m8102339259102339280144-6.01
CAediting_228905chr2_188297554_+ENSG00000023445.12ENST00000615299hsa-miR-561-3p1023371231023371308mer-1a102337107102337130151-8.18
CAediting_1160181chr17_7017644_-ENSG00000023445.12ENST00000532808hsa-miR-195-3p1023378131023378208mer-1a102337799102337820149-9.24
CAediting_688081chr9_63819627_+ENSG00000023445.12ENST00000532808hsa-miR-4477b1023371821023371898mer-1a102337170102337189145-8.44
CAediting_117844chr1_162342605_+ENSG00000023445.12ENST00000532808hsa-miR-556-3p1023392971023393048mer-1a102339283102339304152-9.5
CAediting_228905chr2_188297554_+ENSG00000023445.12ENST00000532808hsa-miR-561-3p1023389071023389137mer-m8102338896102338914143-12.05
CAediting_228905chr2_188297554_+ENSG00000023445.12ENST00000532808hsa-miR-561-3p1023392731023392797mer-m8102339259102339280144-6.01
CAediting_228905chr2_188297554_+ENSG00000023445.12ENST00000532808hsa-miR-561-3p1023371231023371308mer-1a102337107102337130151-8.18

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for BIRC3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for BIRC3

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for BIRC3

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for BIRC3

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for BIRC3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for BIRC3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
BIRC3C0005684Malignant neoplasm of urinary bladder1CTD_human
BIRC3C0005695Bladder Neoplasm1CTD_human
BIRC3C0015695Fatty Liver1CTD_human
BIRC3C0019693HIV Infections1CTD_human
BIRC3C0023418leukemia1CTD_human
BIRC3C0023893Liver Cirrhosis, Experimental1CTD_human
BIRC3C2711227Steatohepatitis1CTD_human
BIRC3C4505456HIV Coinfection1CTD_human