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Editing gene: HCLS1 (CAeditome ID:3059)

Gene summary for HCLS1

Gene summary

Gene information	Gene symbol	HCLS1
	Gene ID	3059
	Gene name	hematopoietic cell-specific Lyn substrate 1
	Synonyms	CTTNL\|HS1\|lckBP1\|p75
	Cytomap	3q13.33
	Type of gene	protein-coding
	Description	hematopoietic lineage cell-specific protein
	Modification date	20210518
	UniProtAcc	P14317
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
HCLS1	GO:0005634	Hematopoietic lineage cell-specific protein	23001182
HCLS1	GO:0005737	Hematopoietic lineage cell-specific protein	23001182
HCLS1	GO:0005829	Hematopoietic lineage cell-specific protein	0000052
HCLS1	GO:0005886	Hematopoietic lineage cell-specific protein	0000052
HCLS1	GO:0005667	Hematopoietic lineage cell-specific protein	23001182

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RNA A-to-I events for HCLS1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000180353.9

RNA A-to-I editing events in Cancer.

CAediting_302633(121637670, -), CAediting_302634(121637679, -), CAediting_302635(121637691, -), CAediting_302636(121637718, -), CAediting_302637(121637731, -), CAediting_302638(121637732, -), CAediting_302639(121637743, -), CAediting_302640(121637752, -), CAediting_302641(121637763, -), CAediting_302642(121637767, -), CAediting_302643(121637824, -), CAediting_302644(121637853, -), CAediting_302645(121637860, -), CAediting_302646(121637873, -), CAediting_302647(121637874, -), CAediting_302648(121637889, -), CAediting_302649(121637897, -), CAediting_302650(121637914, -), CAediting_302651(121637932, -), CAediting_302652(121637934, -), CAediting_302653(121638105, -), CAediting_302654(121638106, -), CAediting_302655(121638111, -), CAediting_302656(121638113, -), CAediting_302657(121638114, -), CAediting_302658(121638117, -), CAediting_302659(121638153, -), CAediting_302660(121638164, -), CAediting_302661(121638167, -), CAediting_302662(121638186, -), CAediting_302663(121638194, -), CAediting_302664(121638210, -), CAediting_302665(121638226, -), CAediting_302666(121638230, -), CAediting_302667(121638251, -), CAediting_302668(121638281, -), CAediting_302669(121638282, -), CAediting_302670(121638287, -), CAediting_302671(121638290, -), CAediting_302672(121638295, -), CAediting_302673(121638335, -), CAediting_302674(121638336, -), CAediting_302675(121638342, -), CAediting_302676(121638349, -), CAediting_302677(121638358, -), CAediting_302678(121638934, -), CAediting_302679(121638946, -), CAediting_302680(121638963, -), CAediting_302681(121638964, -), CAediting_302682(121638998, -), CAediting_302683(121639584, -), CAediting_302684(121639586, -), CAediting_302685(121639587, -), CAediting_302686(121639603, -), CAediting_302687(121639621, -), CAediting_302688(121639622, -), CAediting_302689(121639625, -), CAediting_302690(121639641, -), CAediting_302691(121639651, -), CAediting_302692(121639657, -), CAediting_302693(121639665, -), CAediting_302694(121639673, -), CAediting_302695(121641980, -), CAediting_302696(121642340, -), CAediting_302697(121642560, -), CAediting_302698(121642714, -), CAediting_302699(121642719, -), CAediting_302700(121642734, -), CAediting_302701(121642754, -), CAediting_302702(121649346, -), CAediting_302703(121649351, -), CAediting_302704(121649481, -), CAediting_302705(121649516, -), CAediting_302706(121650881, -), CAediting_302707(121650893, -), CAediting_302708(121650894, -), CAediting_302709(121651048, -), CAediting_302710(121651052, -), CAediting_302711(121651053, -), CAediting_302712(121651529, -), CAediting_302713(121651534, -), CAediting_302714(121651539, -), CAediting_302715(121651542, -), CAediting_302716(121651543, -), CAediting_302717(121651561, -), CAediting_302718(121651596, -), CAediting_302719(121651597, -), CAediting_302720(121651599, -), CAediting_302721(121651603, -), CAediting_302722(121651638, -), CAediting_302723(121651666, -), CAediting_302724(121651679, -), CAediting_302725(121651692, -), CAediting_302726(121651693, -), CAediting_302727(121651709, -), CAediting_302728(121652397, -), CAediting_302729(121652432, -), CAediting_302730(121652449, -), CAediting_302731(121652462, -), CAediting_302732(121652491, -), CAediting_302733(121652505, -), CAediting_302734(121652506, -), CAediting_302735(121652554, -), CAediting_302736(121652559, -), CAediting_302737(121652571, -), CAediting_302738(121652572, -), CAediting_302739(121652578, -), CAediting_302740(121652616, -), CAediting_302741(121654271, -), CAediting_302742(121655914, -), CAediting_302743(121655941, -), CAediting_302744(121655963, -), CAediting_302745(121655973, -), CAediting_302746(121655986, -), CAediting_302747(121655987, -), CAediting_302748(121655993, -), CAediting_302749(121656013, -), CAediting_302750(121656016, -), CAediting_302751(121656017, -), CAediting_302752(121656018, -), CAediting_302753(121656022, -), CAediting_302754(121656025, -), CAediting_302755(121656026, -), CAediting_302756(121656027, -), CAediting_302757(121656028, -), CAediting_302758(121656031, -), CAediting_302759(121656081, -), CAediting_302760(121656091, -), CAediting_302761(121656105, -), CAediting_302762(121656106, -), CAediting_302763(121656113, -), CAediting_302764(121656115, -), CAediting_302765(121656122, -),

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RNA editing positional annotations for HCLS1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_302633	chr3_121637670_-	ncRNA_intronic
CAediting_302634	chr3_121637679_-	ncRNA_intronic
CAediting_302635	chr3_121637691_-	ncRNA_intronic
CAediting_302636	chr3_121637718_-	ncRNA_intronic
CAediting_302637	chr3_121637731_-	ncRNA_intronic
CAediting_302638	chr3_121637732_-	ncRNA_intronic
CAediting_302639	chr3_121637743_-	ncRNA_intronic
CAediting_302640	chr3_121637752_-	ncRNA_intronic
CAediting_302641	chr3_121637763_-	ncRNA_intronic
CAediting_302642	chr3_121637767_-	ncRNA_intronic
CAediting_302643	chr3_121637824_-	ncRNA_intronic
CAediting_302644	chr3_121637853_-	ncRNA_intronic
CAediting_302645	chr3_121637860_-	ncRNA_intronic
CAediting_302646	chr3_121637873_-	ncRNA_intronic
CAediting_302647	chr3_121637874_-	ncRNA_intronic
CAediting_302648	chr3_121637889_-	ncRNA_intronic
CAediting_302649	chr3_121637897_-	ncRNA_intronic
CAediting_302650	chr3_121637914_-	ncRNA_intronic
CAediting_302651	chr3_121637932_-	ncRNA_intronic
CAediting_302652	chr3_121637934_-	ncRNA_intronic
CAediting_302653	chr3_121638105_-	ncRNA_intronic
CAediting_302654	chr3_121638106_-	ncRNA_intronic
CAediting_302655	chr3_121638111_-	ncRNA_intronic
CAediting_302656	chr3_121638113_-	ncRNA_intronic
CAediting_302657	chr3_121638114_-	ncRNA_intronic
CAediting_302658	chr3_121638117_-	ncRNA_intronic
CAediting_302659	chr3_121638153_-	ncRNA_intronic
CAediting_302660	chr3_121638164_-	ncRNA_intronic
CAediting_302661	chr3_121638167_-	ncRNA_intronic
CAediting_302662	chr3_121638186_-	ncRNA_intronic
CAediting_302663	chr3_121638194_-	ncRNA_intronic
CAediting_302664	chr3_121638210_-	ncRNA_intronic
CAediting_302665	chr3_121638226_-	ncRNA_intronic
CAediting_302666	chr3_121638230_-	ncRNA_intronic
CAediting_302667	chr3_121638251_-	ncRNA_intronic
CAediting_302668	chr3_121638281_-	ncRNA_intronic
CAediting_302669	chr3_121638282_-	ncRNA_intronic
CAediting_302670	chr3_121638287_-	ncRNA_intronic
CAediting_302671	chr3_121638290_-	ncRNA_intronic
CAediting_302672	chr3_121638295_-	ncRNA_intronic
CAediting_302673	chr3_121638335_-	ncRNA_intronic
CAediting_302674	chr3_121638336_-	ncRNA_intronic
CAediting_302675	chr3_121638342_-	ncRNA_intronic
CAediting_302676	chr3_121638349_-	ncRNA_intronic
CAediting_302677	chr3_121638358_-	ncRNA_intronic
CAediting_302678	chr3_121638934_-	ncRNA_intronic
CAediting_302679	chr3_121638946_-	ncRNA_intronic
CAediting_302680	chr3_121638963_-	ncRNA_intronic
CAediting_302681	chr3_121638964_-	ncRNA_intronic
CAediting_302682	chr3_121638998_-	ncRNA_intronic
CAediting_302683	chr3_121639584_-	ncRNA_intronic
CAediting_302684	chr3_121639586_-	ncRNA_intronic
CAediting_302685	chr3_121639587_-	ncRNA_intronic
CAediting_302686	chr3_121639603_-	ncRNA_intronic
CAediting_302687	chr3_121639621_-	ncRNA_intronic
CAediting_302688	chr3_121639622_-	ncRNA_intronic
CAediting_302689	chr3_121639625_-	ncRNA_intronic
CAediting_302690	chr3_121639641_-	ncRNA_intronic
CAediting_302691	chr3_121639651_-	ncRNA_intronic
CAediting_302692	chr3_121639657_-	ncRNA_intronic
CAediting_302693	chr3_121639665_-	ncRNA_intronic
CAediting_302694	chr3_121639673_-	ncRNA_intronic
CAediting_302695	chr3_121641980_-	ncRNA_intronic
CAediting_302696	chr3_121642340_-	ncRNA_intronic
CAediting_302697	chr3_121642560_-	ncRNA_intronic
CAediting_302698	chr3_121642714_-	ncRNA_intronic
CAediting_302699	chr3_121642719_-	ncRNA_intronic
CAediting_302700	chr3_121642734_-	ncRNA_intronic
CAediting_302701	chr3_121642754_-	ncRNA_intronic
CAediting_302702	chr3_121649346_-	ncRNA_intronic
CAediting_302703	chr3_121649351_-	ncRNA_intronic
CAediting_302704	chr3_121649481_-	ncRNA_intronic
CAediting_302705	chr3_121649516_-	ncRNA_intronic
CAediting_302706	chr3_121650881_-	ncRNA_intronic
CAediting_302707	chr3_121650893_-	ncRNA_intronic
CAediting_302708	chr3_121650894_-	ncRNA_intronic
CAediting_302709	chr3_121651048_-	ncRNA_intronic
CAediting_302710	chr3_121651052_-	ncRNA_intronic
CAediting_302711	chr3_121651053_-	ncRNA_intronic
CAediting_302712	chr3_121651529_-	ncRNA_intronic
CAediting_302713	chr3_121651534_-	ncRNA_intronic
CAediting_302714	chr3_121651539_-	ncRNA_intronic
CAediting_302715	chr3_121651542_-	ncRNA_intronic
CAediting_302716	chr3_121651543_-	ncRNA_intronic
CAediting_302717	chr3_121651561_-	ncRNA_intronic
CAediting_302718	chr3_121651596_-	ncRNA_intronic
CAediting_302719	chr3_121651597_-	ncRNA_intronic
CAediting_302720	chr3_121651599_-	ncRNA_intronic
CAediting_302721	chr3_121651603_-	ncRNA_intronic
CAediting_302722	chr3_121651638_-	ncRNA_intronic
CAediting_302723	chr3_121651666_-	ncRNA_intronic
CAediting_302724	chr3_121651679_-	ncRNA_intronic
CAediting_302725	chr3_121651692_-	ncRNA_intronic
CAediting_302726	chr3_121651693_-	ncRNA_intronic
CAediting_302727	chr3_121651709_-	ncRNA_intronic
CAediting_302728	chr3_121652397_-	ncRNA_intronic
CAediting_302729	chr3_121652432_-	ncRNA_intronic
CAediting_302730	chr3_121652449_-	ncRNA_intronic
CAediting_302731	chr3_121652462_-	ncRNA_intronic
CAediting_302732	chr3_121652491_-	ncRNA_intronic
CAediting_302733	chr3_121652505_-	ncRNA_intronic
CAediting_302734	chr3_121652506_-	ncRNA_intronic
CAediting_302735	chr3_121652554_-	ncRNA_intronic
CAediting_302736	chr3_121652559_-	ncRNA_intronic
CAediting_302737	chr3_121652571_-	ncRNA_intronic
CAediting_302738	chr3_121652572_-	ncRNA_intronic
CAediting_302739	chr3_121652578_-	ncRNA_intronic
CAediting_302740	chr3_121652616_-	ncRNA_intronic
CAediting_302741	chr3_121654271_-	ncRNA_exonic
CAediting_302742	chr3_121655914_-	ncRNA_intronic
CAediting_302743	chr3_121655941_-	ncRNA_intronic
CAediting_302744	chr3_121655963_-	ncRNA_intronic
CAediting_302745	chr3_121655973_-	ncRNA_intronic
CAediting_302746	chr3_121655986_-	ncRNA_intronic
CAediting_302747	chr3_121655987_-	ncRNA_intronic
CAediting_302748	chr3_121655993_-	ncRNA_intronic
CAediting_302749	chr3_121656013_-	ncRNA_intronic
CAediting_302750	chr3_121656016_-	ncRNA_intronic
CAediting_302751	chr3_121656017_-	ncRNA_intronic
CAediting_302752	chr3_121656018_-	ncRNA_intronic
CAediting_302753	chr3_121656022_-	ncRNA_intronic
CAediting_302754	chr3_121656025_-	ncRNA_intronic
CAediting_302755	chr3_121656026_-	ncRNA_intronic
CAediting_302756	chr3_121656027_-	ncRNA_intronic
CAediting_302757	chr3_121656028_-	ncRNA_intronic
CAediting_302758	chr3_121656031_-	ncRNA_intronic
CAediting_302759	chr3_121656081_-	ncRNA_exonic
CAediting_302760	chr3_121656091_-	ncRNA_exonic
CAediting_302761	chr3_121656105_-	ncRNA_exonic
CAediting_302762	chr3_121656106_-	ncRNA_exonic
CAediting_302763	chr3_121656113_-	ncRNA_exonic
CAediting_302764	chr3_121656115_-	ncRNA_exonic
CAediting_302765	chr3_121656122_-	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_302633	chr3_121637670_-	SINE	Alu	AluSx
CAediting_302634	chr3_121637679_-	SINE	Alu	AluSx
CAediting_302635	chr3_121637691_-	SINE	Alu	AluSx
CAediting_302636	chr3_121637718_-	SINE	Alu	AluSx
CAediting_302637	chr3_121637731_-	SINE	Alu	AluSx
CAediting_302638	chr3_121637732_-	SINE	Alu	AluSx
CAediting_302639	chr3_121637743_-	SINE	Alu	AluSx
CAediting_302640	chr3_121637752_-	SINE	Alu	AluSx
CAediting_302641	chr3_121637763_-	SINE	Alu	AluSx
CAediting_302642	chr3_121637767_-	SINE	Alu	AluSx
CAediting_302643	chr3_121637824_-	SINE	Alu	AluSx
CAediting_302644	chr3_121637853_-	SINE	Alu	AluSx
CAediting_302645	chr3_121637860_-	SINE	Alu	AluSx
CAediting_302646	chr3_121637873_-	SINE	Alu	AluSx
CAediting_302647	chr3_121637874_-	SINE	Alu	AluSx
CAediting_302648	chr3_121637889_-	SINE	Alu	AluSx
CAediting_302649	chr3_121637897_-	SINE	Alu	AluSx
CAediting_302650	chr3_121637914_-	SINE	Alu	AluSx
CAediting_302651	chr3_121637932_-	SINE	Alu	AluSx
CAediting_302652	chr3_121637934_-	SINE	Alu	AluSx
CAediting_302653	chr3_121638105_-	SINE	Alu	AluJr4
CAediting_302654	chr3_121638106_-	SINE	Alu	AluJr4
CAediting_302655	chr3_121638111_-	SINE	Alu	AluJr4
CAediting_302656	chr3_121638113_-	SINE	Alu	AluJr4
CAediting_302657	chr3_121638114_-	SINE	Alu	AluJr4
CAediting_302658	chr3_121638117_-	SINE	Alu	AluJr4
CAediting_302659	chr3_121638153_-	SINE	Alu	AluJr4
CAediting_302660	chr3_121638164_-	SINE	Alu	AluJr4
CAediting_302661	chr3_121638167_-	SINE	Alu	AluJr4
CAediting_302662	chr3_121638186_-	SINE	Alu	AluJr4
CAediting_302663	chr3_121638194_-	SINE	Alu	AluJr4
CAediting_302664	chr3_121638210_-	SINE	Alu	AluJr4
CAediting_302665	chr3_121638226_-	SINE	Alu	AluJr4
CAediting_302666	chr3_121638230_-	SINE	Alu	AluJr4
CAediting_302667	chr3_121638251_-	SINE	Alu	AluJr4
CAediting_302668	chr3_121638281_-	SINE	Alu	AluJr4
CAediting_302669	chr3_121638282_-	SINE	Alu	AluJr4
CAediting_302670	chr3_121638287_-	SINE	Alu	AluJr4
CAediting_302671	chr3_121638290_-	SINE	Alu	AluJr4
CAediting_302672	chr3_121638295_-	SINE	Alu	AluJr4
CAediting_302673	chr3_121638335_-	SINE	Alu	AluJr4
CAediting_302674	chr3_121638336_-	SINE	Alu	AluJr4
CAediting_302675	chr3_121638342_-	SINE	Alu	AluJr4
CAediting_302676	chr3_121638349_-	SINE	Alu	AluJr4
CAediting_302677	chr3_121638358_-	SINE	Alu	AluJr4
CAediting_302678	chr3_121638934_-	SINE	Alu	AluJo
CAediting_302679	chr3_121638946_-	SINE	Alu	AluJo
CAediting_302680	chr3_121638963_-	SINE	Alu	AluJo
CAediting_302681	chr3_121638964_-	SINE	Alu	AluJo
CAediting_302683	chr3_121639584_-	SINE	Alu	AluJb
CAediting_302684	chr3_121639586_-	SINE	Alu	AluJb
CAediting_302685	chr3_121639587_-	SINE	Alu	AluJb
CAediting_302686	chr3_121639603_-	SINE	Alu	AluJb
CAediting_302687	chr3_121639621_-	SINE	Alu	AluJb
CAediting_302688	chr3_121639622_-	SINE	Alu	AluJb
CAediting_302689	chr3_121639625_-	SINE	Alu	AluJb
CAediting_302690	chr3_121639641_-	SINE	Alu	AluJb
CAediting_302691	chr3_121639651_-	SINE	Alu	AluJb
CAediting_302692	chr3_121639657_-	SINE	Alu	AluJb
CAediting_302693	chr3_121639665_-	SINE	Alu	AluJb
CAediting_302694	chr3_121639673_-	SINE	Alu	AluJb
CAediting_302695	chr3_121641980_-	SINE	Alu	AluYm1
CAediting_302696	chr3_121642340_-	SINE	Alu	AluY
CAediting_302697	chr3_121642560_-	SINE	Alu	AluJb
CAediting_302698	chr3_121642714_-	SINE	Alu	AluJb
CAediting_302699	chr3_121642719_-	SINE	Alu	AluJb
CAediting_302700	chr3_121642734_-	SINE	Alu	AluJb
CAediting_302701	chr3_121642754_-	SINE	Alu	AluJb
CAediting_302702	chr3_121649346_-	SINE	Alu	AluSz
CAediting_302703	chr3_121649351_-	SINE	Alu	AluSz
CAediting_302704	chr3_121649481_-	SINE	Alu	AluSz
CAediting_302705	chr3_121649516_-	SINE	Alu	AluSz
CAediting_302706	chr3_121650881_-	SINE	Alu	AluSx4
CAediting_302707	chr3_121650893_-	SINE	Alu	AluSx4
CAediting_302708	chr3_121650894_-	SINE	Alu	AluSx4
CAediting_302709	chr3_121651048_-	SINE	Alu	AluSx4
CAediting_302710	chr3_121651052_-	SINE	Alu	AluSx4
CAediting_302711	chr3_121651053_-	SINE	Alu	AluSx4
CAediting_302712	chr3_121651529_-	SINE	Alu	AluJb
CAediting_302713	chr3_121651534_-	SINE	Alu	AluJb
CAediting_302714	chr3_121651539_-	SINE	Alu	AluJb
CAediting_302715	chr3_121651542_-	SINE	Alu	AluJb
CAediting_302716	chr3_121651543_-	SINE	Alu	AluJb
CAediting_302717	chr3_121651561_-	SINE	Alu	AluJb
CAediting_302718	chr3_121651596_-	SINE	Alu	AluJb
CAediting_302719	chr3_121651597_-	SINE	Alu	AluJb
CAediting_302720	chr3_121651599_-	SINE	Alu	AluJb
CAediting_302721	chr3_121651603_-	SINE	Alu	AluJb
CAediting_302722	chr3_121651638_-	SINE	Alu	AluJb
CAediting_302723	chr3_121651666_-	SINE	Alu	AluJb
CAediting_302724	chr3_121651679_-	SINE	Alu	AluJb
CAediting_302725	chr3_121651692_-	SINE	Alu	AluJb
CAediting_302726	chr3_121651693_-	SINE	Alu	AluJb
CAediting_302727	chr3_121651709_-	SINE	Alu	AluJb
CAediting_302728	chr3_121652397_-	SINE	Alu	AluSz
CAediting_302729	chr3_121652432_-	SINE	Alu	AluSz
CAediting_302730	chr3_121652449_-	SINE	Alu	AluSz
CAediting_302731	chr3_121652462_-	SINE	Alu	AluSz
CAediting_302732	chr3_121652491_-	SINE	Alu	AluSz
CAediting_302733	chr3_121652505_-	SINE	Alu	AluSz
CAediting_302734	chr3_121652506_-	SINE	Alu	AluSz
CAediting_302735	chr3_121652554_-	SINE	Alu	AluSz
CAediting_302736	chr3_121652559_-	SINE	Alu	AluSz
CAediting_302737	chr3_121652571_-	SINE	Alu	AluSz
CAediting_302738	chr3_121652572_-	SINE	Alu	AluSz
CAediting_302739	chr3_121652578_-	SINE	Alu	AluSz
CAediting_302740	chr3_121652616_-	SINE	Alu	AluSz
CAediting_302741	chr3_121654271_-	srpRNA	srpRNA	7SLRNA
CAediting_302742	chr3_121655914_-	SINE	Alu	AluSx1
CAediting_302743	chr3_121655941_-	SINE	Alu	AluSx1
CAediting_302744	chr3_121655963_-	SINE	Alu	AluSx1
CAediting_302745	chr3_121655973_-	SINE	Alu	AluSx1
CAediting_302746	chr3_121655986_-	SINE	Alu	AluSx1
CAediting_302747	chr3_121655987_-	SINE	Alu	AluSx1
CAediting_302748	chr3_121655993_-	SINE	Alu	AluSx1
CAediting_302749	chr3_121656013_-	SINE	Alu	AluSx1
CAediting_302750	chr3_121656016_-	SINE	Alu	AluSx1
CAediting_302751	chr3_121656017_-	SINE	Alu	AluSx1
CAediting_302752	chr3_121656018_-	SINE	Alu	AluSx1
CAediting_302753	chr3_121656022_-	SINE	Alu	AluSx1
CAediting_302754	chr3_121656025_-	SINE	Alu	AluSx1
CAediting_302755	chr3_121656026_-	SINE	Alu	AluSx1
CAediting_302756	chr3_121656027_-	SINE	Alu	AluSx1
CAediting_302757	chr3_121656028_-	SINE	Alu	AluSx1
CAediting_302758	chr3_121656031_-	SINE	Alu	AluSx1
CAediting_302759	chr3_121656081_-	SINE	Alu	AluSx1
CAediting_302760	chr3_121656091_-	SINE	Alu	AluSx1
CAediting_302761	chr3_121656105_-	SINE	Alu	AluSx1
CAediting_302762	chr3_121656106_-	SINE	Alu	AluSx1
CAediting_302763	chr3_121656113_-	SINE	Alu	AluSx1
CAediting_302764	chr3_121656115_-	SINE	Alu	AluSx1
CAediting_302765	chr3_121656122_-	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for HCLS1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000180353.9.HCLS1.

Correlation between RNA A-to-I editing and PSI for ENSG00000180353.9.HCLS1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HCLS1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for HCLS1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for HCLS1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_86358	chr1_109598906_+	ENSG00000180353.9	ENST00000314583	hsa-miR-197-5p	121631784	121631790	7mer-m8	121631783	121631809	155	-27.52
CAediting_86358	chr1_109598906_+	ENSG00000180353.9	ENST00000428394	hsa-miR-197-5p	121631784	121631790	7mer-m8	121631783	121631809	155	-27.52
CAediting_1368054	chr19_46709310_-	ENSG00000180353.9	ENST00000495491	hsa-miR-320e	121632542	121632548	7mer-m8	121632541	121632558	145	-17.64
CAediting_468389	chr6_31355314_-	ENSG00000180353.9	ENST00000314583	hsa-miR-6891-5p	121631568	121631573	6mer	121631564	121631583	151	-23.69
CAediting_468389	chr6_31355314_-	ENSG00000180353.9	ENST00000314583	hsa-miR-6891-5p	121631565	121631571	7mer-m8	121631564	121631583	151	-23.69

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for HCLS1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000468693.4	processed_transcript

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_302759	ENST00000468693.4	chr3_121656081_-	-150.80	-150.70	-154.00
CAediting_302760	ENST00000468693.4	chr3_121656091_-	-150.70	-150.70	-154.00
CAediting_302761	ENST00000468693.4	chr3_121656105_-	-150.90	-150.70	-154.00
CAediting_302762	ENST00000468693.4	chr3_121656106_-	-155.20	-150.70	-154.00
CAediting_302763	ENST00000468693.4	chr3_121656113_-	-150.70	-150.70	-154.00
CAediting_302764	ENST00000468693.4	chr3_121656115_-	-150.90	-150.70	-154.00
CAediting_302765	ENST00000468693.4	chr3_121656122_-	-150.70	-150.70	-154.00

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Relation with ADAR for HCLS1

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LUSC	CAediting_302659	chr3_121638153_-	0.000442373345238225	0.357066592501455	.	.	.	.

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Relation with cancer stages for HCLS1

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRC	pathologic_stage	CAediting_302659	chr3_121638153_-	3.56760235994005e-05	0.365019604565828
LUAD	pathologic_stage	CAediting_302659	chr3_121638153_-	0.0244350428056222	0.278952380714199

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Relation with survival for HCLS1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for HCLS1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for HCLS1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
HCLS1	C0003873	Rheumatoid Arthritis	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene