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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: UBQLN2 (CAeditome ID:29978) |
Gene summary for UBQLN2 |
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Gene information | Gene symbol | UBQLN2 | Gene ID | 29978 |
Gene name | ubiquilin 2 | |
Synonyms | ALS15|CHAP1|DSK2|HRIHFB2157|N4BP4|PLIC2 | |
Cytomap | Xp11.21 | |
Type of gene | protein-coding | |
Description | ubiquilin-2Nedd4 binding protein 4protein linking IAP with cytoskeleton 2ubiquitin-like product Chap1/Dsk2 | |
Modification date | 20210524 | |
UniProtAcc | Q9UHD9 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
UBQLN2 | GO:0005737 | Ubiquilin-2 | 18199683 |
UBQLN2 | GO:0005829 | Ubiquilin-2 | 0000052 |
UBQLN2 | GO:0005886 | Ubiquilin-2 | 0000052 |
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RNA A-to-I events for UBQLN2 |
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CAediting_1509111(56564261, +), CAediting_1509112(56564267, +), |
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RNA editing positional annotations for UBQLN2 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_1509111 | chrX_56564261_+ | exonic |
CAediting_1509112 | chrX_56564267_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for UBQLN2 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for UBQLN2 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for UBQLN2 |
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The effects of the RNA editing to the miRNA binding sites for UBQLN2 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_1160181 | chr17_7017644_- | ENSG00000188021.8 | ENST00000338222 | hsa-miR-195-3p | 56567229 | 56567235 | 7mer-m8 | 56567215 | 56567236 | 145 | -10.18 |
CAediting_1160181 | chr17_7017644_- | ENSG00000188021.8 | ENST00000338222 | hsa-miR-195-3p | 56566627 | 56566633 | 7mer-m8 | 56566612 | 56566634 | 154 | -14.19 |
CAediting_1351755 | chr19_40282625_- | ENSG00000188021.8 | ENST00000338222 | hsa-miR-641 | 56566479 | 56566486 | 8mer-1a | 56566464 | 56566486 | 154 | -18.06 |
CAediting_573001 | chr7_92204086_- | ENSG00000188021.8 | ENST00000338222 | hsa-miR-1285-5p | 56567293 | 56567299 | 7mer-m8 | 56567280 | 56567300 | 148 | -15.5 |
CAediting_468389 | chr6_31355314_- | ENSG00000188021.8 | ENST00000338222 | hsa-miR-6891-5p | 56567299 | 56567305 | 7mer-m8 | 56567288 | 56567306 | 140 | -14.14 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_1229415 | chr17_67471547_+ | ENSG00000188021.8 | ENST00000338222 | hsa-miR-548aa | 56567046 | 56567053 | 8mer-1a | 56567030 | 56567053 | 147 | -5.98 |
CAediting_228905 | chr2_188297554_+ | ENSG00000188021.8 | ENST00000338222 | hsa-miR-561-3p | 56567496 | 56567503 | 8mer-1a | 56567482 | 56567503 | 140 | -5.99 |
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The effects of the RNA editing to the stability of the RNA structures for UBQLN2 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for UBQLN2 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for UBQLN2 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for UBQLN2 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for UBQLN2 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBQLN2 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
UBQLN2 | C3275459 | AMYOTROPHIC LATERAL SCLEROSIS 15, WITH OR WITHOUT FRONTOTEMPORAL DEMENTIA | 6 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
UBQLN2 | C0002736 | Amyotrophic Lateral Sclerosis | 1 | ORPHANET |