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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: IGKV1-17 (CAeditome ID:28937) |
Gene summary for IGKV1-17 |
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Gene information | Gene symbol | IGKV1-17 | Gene ID | 28937 |
Gene name | immunoglobulin kappa variable 1-17 | |
Synonyms | A30|IGKV117 | |
Cytomap | 2p11.2 | |
Type of gene | other | |
Description | Ig kappa chain V-I region Gal | |
Modification date | 20210518 | |
UniProtAcc | P01599 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for IGKV1-17 |
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CAediting_198752(89117470, -), CAediting_198753(89117501, -), CAediting_198754(89117502, -), CAediting_198755(89117528, -), CAediting_198756(89117532, -), CAediting_198757(89117537, -), CAediting_198758(89117551, -), |
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RNA editing positional annotations for IGKV1-17 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_198752 | chr2_89117470_- | exonic |
CAediting_198753 | chr2_89117501_- | exonic |
CAediting_198754 | chr2_89117502_- | exonic |
CAediting_198755 | chr2_89117528_- | exonic |
CAediting_198756 | chr2_89117532_- | exonic |
CAediting_198757 | chr2_89117537_- | exonic |
CAediting_198758 | chr2_89117551_- | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for IGKV1-17 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for IGKV1-17 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for IGKV1-17 |
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The effects of the RNA editing to the miRNA binding sites for IGKV1-17 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for IGKV1-17 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
ENST00000490686.1 | IG_V_gene | ![]() | ![]() |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
CAediting_198752 | ENST00000490686.1 | chr2_89117470_- | -117.60 | -118.30 | -127.30 |
CAediting_198753 | ENST00000490686.1 | chr2_89117501_- | -118.30 | -118.30 | -127.30 |
CAediting_198754 | ENST00000490686.1 | chr2_89117502_- | -118.30 | -118.30 | -127.30 |
CAediting_198755 | ENST00000490686.1 | chr2_89117528_- | -118.00 | -118.30 | -127.30 |
CAediting_198756 | ENST00000490686.1 | chr2_89117532_- | -125.00 | -118.30 | -127.30 |
CAediting_198757 | ENST00000490686.1 | chr2_89117537_- | -120.40 | -118.30 | -127.30 |
CAediting_198758 | ENST00000490686.1 | chr2_89117551_- | -120.30 | -118.30 | -127.30 |
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Relation with ADAR for IGKV1-17 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
BRCA | CAediting_198755 | chr2_89117528_- | 0.018854429607166 | 0.280086984471019 | . | . | . | . |
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Relation with cancer stages for IGKV1-17 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for IGKV1-17 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for IGKV1-17 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
IGKV1-17 | P01599 | DB01593 | Zinc | Immunoglobulin kappa variable 1-17 | SmallMoleculeDrug | approved|investigational |
IGKV1-17 | P01599 | DB14487 | Zinc acetate | Immunoglobulin kappa variable 1-17 | SmallMoleculeDrug | approved|investigational |
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RelatedDiseases for IGKV1-17 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |