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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ZFP41 (CAeditome ID:286128)

Gene summary for ZFP41

check button Gene summary
Gene informationGene symbol

ZFP41

Gene ID

286128

Gene nameZFP41 zinc finger protein
SynonymsZNF753|zfp-41
Cytomap

8q24.3

Type of geneprotein-coding
Descriptionzinc finger protein 41 homolog
Modification date20210518
UniProtAcc

Q8N8Y5

.

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ZFP41

GO:1990837

Zinc finger protein 41 homolog

28473536


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RNA A-to-I events for ZFP41

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000181638.16

check button RNA A-to-I editing events in Cancer.
CAediting_669623(143247894, +), CAediting_669624(143247919, +), CAediting_669625(143247937, +), CAediting_669626(143247959, +), CAediting_669627(143248080, +), CAediting_669628(143249157, +), CAediting_669629(143249175, +), CAediting_669630(143254694, +), CAediting_669631(143254702, +), CAediting_669632(143254710, +), CAediting_669633(143254719, +), CAediting_669634(143254762, +), CAediting_669635(143254807, +), CAediting_669636(143254813, +), CAediting_669637(143257307, +), CAediting_669638(143257447, +), CAediting_669639(143258048, +), CAediting_669640(143258107, +), CAediting_669641(143258142, +), CAediting_669642(143258230, +), CAediting_669643(143265096, +), CAediting_669644(143265097, +), CAediting_669645(143265127, +), CAediting_669646(143265136, +), CAediting_669647(143265142, +), CAediting_669648(143265146, +), CAediting_669649(143265163, +), CAediting_669650(143265169, +), CAediting_669651(143265171, +), CAediting_669652(143265198, +), CAediting_669653(143265206, +), CAediting_669654(143265207, +), CAediting_669655(143265297, +), CAediting_669656(143265314, +), CAediting_669657(143265331, +), CAediting_669658(143265368, +), CAediting_669659(143265383, +), CAediting_669660(143265391, +), CAediting_669661(143265393, +), CAediting_669662(143265404, +), CAediting_669663(143265448, +), CAediting_669664(143265453, +), CAediting_669665(143265457, +), CAediting_669666(143265566, +), CAediting_669667(143265755, +), CAediting_669668(143265965, +), CAediting_669669(143265967, +), CAediting_669670(143266042, +), CAediting_669671(143266068, +), CAediting_669672(143266069, +), CAediting_669673(143266072, +), CAediting_669674(143266117, +), CAediting_669675(143266165, +), CAediting_669676(143266167, +), CAediting_669677(143267742, +), CAediting_669678(143268969, +), CAediting_669679(143268973, +), CAediting_669680(143269027, +), CAediting_669681(143269041, +), CAediting_669682(143269046, +), CAediting_669683(143272314, +),

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RNA editing positional annotations for ZFP41 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_669623chr8_143247894_+ncRNA_intronic
CAediting_669624chr8_143247919_+ncRNA_intronic
CAediting_669625chr8_143247937_+ncRNA_intronic
CAediting_669626chr8_143247959_+ncRNA_intronic
CAediting_669627chr8_143248080_+ncRNA_intronic
CAediting_669628chr8_143249157_+ncRNA_exonic
CAediting_669629chr8_143249175_+ncRNA_exonic
CAediting_669630chr8_143254694_+intronic
CAediting_669631chr8_143254702_+intronic
CAediting_669632chr8_143254710_+intronic
CAediting_669633chr8_143254719_+intronic
CAediting_669634chr8_143254762_+intronic
CAediting_669635chr8_143254807_+intronic
CAediting_669636chr8_143254813_+intronic
CAediting_669637chr8_143257307_+intronic
CAediting_669638chr8_143257447_+intronic
CAediting_669639chr8_143258048_+intronic
CAediting_669640chr8_143258107_+intronic
CAediting_669641chr8_143258142_+intronic
CAediting_669642chr8_143258230_+intronic
CAediting_669643chr8_143265096_+intronic
CAediting_669644chr8_143265097_+intronic
CAediting_669645chr8_143265127_+intronic
CAediting_669646chr8_143265136_+intronic
CAediting_669647chr8_143265142_+intronic
CAediting_669648chr8_143265146_+intronic
CAediting_669649chr8_143265163_+intronic
CAediting_669650chr8_143265169_+intronic
CAediting_669651chr8_143265171_+intronic
CAediting_669652chr8_143265198_+intronic
CAediting_669653chr8_143265206_+intronic
CAediting_669654chr8_143265207_+intronic
CAediting_669655chr8_143265297_+intronic
CAediting_669656chr8_143265314_+intronic
CAediting_669657chr8_143265331_+intronic
CAediting_669658chr8_143265368_+intronic
CAediting_669659chr8_143265383_+intronic
CAediting_669660chr8_143265391_+intronic
CAediting_669661chr8_143265393_+intronic
CAediting_669662chr8_143265404_+intronic
CAediting_669663chr8_143265448_+intronic
CAediting_669664chr8_143265453_+intronic
CAediting_669665chr8_143265457_+intronic
CAediting_669666chr8_143265566_+intronic
CAediting_669667chr8_143265755_+intronic
CAediting_669668chr8_143265965_+intronic
CAediting_669669chr8_143265967_+intronic
CAediting_669670chr8_143266042_+intronic
CAediting_669671chr8_143266068_+intronic
CAediting_669672chr8_143266069_+intronic
CAediting_669673chr8_143266072_+intronic
CAediting_669674chr8_143266117_+intronic
CAediting_669675chr8_143266165_+intronic
CAediting_669676chr8_143266167_+intronic
CAediting_669677chr8_143267742_+ncRNA_intronic
CAediting_669678chr8_143268969_+ncRNA_intronic
CAediting_669679chr8_143268973_+ncRNA_intronic
CAediting_669680chr8_143269027_+ncRNA_intronic
CAediting_669681chr8_143269041_+ncRNA_intronic
CAediting_669682chr8_143269046_+ncRNA_intronic
CAediting_669683chr8_143272314_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_669623chr8_143247894_+SINEAluAluSc8
CAediting_669624chr8_143247919_+SINEAluAluSc8
CAediting_669625chr8_143247937_+SINEAluAluSc8
CAediting_669626chr8_143247959_+SINEAluAluSc8
CAediting_669627chr8_143248080_+SINEAluAluSc8
CAediting_669628chr8_143249157_+SINEAluFRAM
CAediting_669629chr8_143249175_+SINEAluFRAM
CAediting_669630chr8_143254694_+SINEAluAluSc
CAediting_669631chr8_143254702_+SINEAluAluSc
CAediting_669632chr8_143254710_+SINEAluAluSc
CAediting_669633chr8_143254719_+SINEAluAluSc
CAediting_669634chr8_143254762_+SINEAluAluSc
CAediting_669635chr8_143254807_+SINEAluAluSc
CAediting_669636chr8_143254813_+SINEAluAluSc
CAediting_669637chr8_143257307_+SINEAluAluSq2
CAediting_669638chr8_143257447_+SINEAluAluSq2
CAediting_669639chr8_143258048_+SINEAluAluJo
CAediting_669640chr8_143258107_+SINEAluAluJo
CAediting_669641chr8_143258142_+SINEAluAluJo
CAediting_669642chr8_143258230_+SINEAluAluJo
CAediting_669643chr8_143265096_+LTRERVL-MaLRMSTB
CAediting_669644chr8_143265097_+LTRERVL-MaLRMSTB
CAediting_669645chr8_143265127_+SINEAluAluYc
CAediting_669646chr8_143265136_+SINEAluAluYc
CAediting_669647chr8_143265142_+SINEAluAluYc
CAediting_669648chr8_143265146_+SINEAluAluYc
CAediting_669649chr8_143265163_+SINEAluAluYc
CAediting_669650chr8_143265169_+SINEAluAluYc
CAediting_669651chr8_143265171_+SINEAluAluYc
CAediting_669652chr8_143265198_+SINEAluAluYc
CAediting_669653chr8_143265206_+SINEAluAluYc
CAediting_669654chr8_143265207_+SINEAluAluYc
CAediting_669655chr8_143265297_+SINEAluAluSq2
CAediting_669656chr8_143265314_+SINEAluAluSq2
CAediting_669657chr8_143265331_+SINEAluAluSq2
CAediting_669658chr8_143265368_+SINEAluAluSq2
CAediting_669659chr8_143265383_+SINEAluAluSq2
CAediting_669660chr8_143265391_+SINEAluAluSq2
CAediting_669661chr8_143265393_+SINEAluAluSq2
CAediting_669662chr8_143265404_+SINEAluAluSq2
CAediting_669663chr8_143265448_+SINEAluAluSq2
CAediting_669664chr8_143265453_+SINEAluAluSq2
CAediting_669665chr8_143265457_+SINEAluAluSq2
CAediting_669666chr8_143265566_+SINEAluAluSq2
CAediting_669667chr8_143265755_+LTRERVL-MaLRMSTB
CAediting_669668chr8_143265965_+SINEAluAluSx1
CAediting_669669chr8_143265967_+SINEAluAluSx1
CAediting_669670chr8_143266042_+SINEAluAluSx1
CAediting_669671chr8_143266068_+SINEAluAluSx1
CAediting_669672chr8_143266069_+SINEAluAluSx1
CAediting_669673chr8_143266072_+SINEAluAluSx1
CAediting_669674chr8_143266117_+SINEAluAluSx1
CAediting_669675chr8_143266165_+SINEAluAluSx1
CAediting_669676chr8_143266167_+SINEAluAluSx1
CAediting_669677chr8_143267742_+SINEMIRMIRb
CAediting_669678chr8_143268969_+SINEAluAluSg4
CAediting_669679chr8_143268973_+SINEAluAluSg4
CAediting_669680chr8_143269027_+SINEAluAluSg4
CAediting_669681chr8_143269041_+SINEAluAluSg4
CAediting_669682chr8_143269046_+SINEAluAluSg4

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RNA A-to-I editing events in the alternative splicing sites for ZFP41

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000181638.16.ZFP41.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000181638.16.ZFP41.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZFP41

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZFP41

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ZFP41

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000181638.16ENST00000520584hsa-miR-605-3p1432509141432509207mer-m8143250903143250921142-22.43
CAediting_748296chr10_51299626_+ENSG00000181638.16ENST00000520584hsa-miR-605-3p1432511101432511167mer-m8143251094143251117146-23.23
CAediting_748296chr10_51299626_+ENSG00000181638.16ENST00000520584hsa-miR-605-3p1432512471432512537mer-m8143251233143251254147-18.49
CAediting_846604chr11_93733708_-ENSG00000181638.16ENST00000520584hsa-miR-1304-3p1432506051432506117mer-m8143250591143250612142-22.47
CAediting_846604chr11_93733708_-ENSG00000181638.16ENST00000520584hsa-miR-1304-3p1432509381432509447mer-m8143250923143250945159-27.03
CAediting_393chr1_1167164_+ENSG00000181638.16ENST00000520584hsa-miR-200b-3p1432513301432513367mer-m8143251315143251337153-16.83
CAediting_748296chr10_51299626_+ENSG00000181638.16ENST00000330701hsa-miR-605-3p1432509141432509207mer-m8143250903143250921142-22.43
CAediting_748296chr10_51299626_+ENSG00000181638.16ENST00000330701hsa-miR-605-3p1432511101432511167mer-m8143251094143251117146-23.23
CAediting_748296chr10_51299626_+ENSG00000181638.16ENST00000330701hsa-miR-605-3p1432512471432512537mer-m8143251233143251254147-18.49
CAediting_846604chr11_93733708_-ENSG00000181638.16ENST00000330701hsa-miR-1304-3p1432506051432506117mer-m8143250591143250612142-22.47
CAediting_846604chr11_93733708_-ENSG00000181638.16ENST00000330701hsa-miR-1304-3p1432509381432509447mer-m8143250923143250945159-27.03
CAediting_393chr1_1167164_+ENSG00000181638.16ENST00000330701hsa-miR-200b-3p1432513301432513367mer-m8143251315143251337153-16.83
CAediting_846604chr11_93733708_-ENSG00000181638.16ENST00000330701hsa-miR-1304-3p1432613231432613297mer-m8143261309143261330148-25.22
CAediting_846604chr11_93733708_-ENSG00000181638.16ENST00000330701hsa-miR-1304-3p1432622231432622297mer-m8143262209143262230149-17.71
CAediting_980496chr14_31014685_-ENSG00000181638.16ENST00000330701hsa-miR-624-3p1432600261432600327mer-m8143260013143260033143-18.66
CAediting_980496chr14_31014685_-ENSG00000181638.16ENST00000330701hsa-miR-624-3p1432600511432600577mer-m8143260038143260058143-18.66
CAediting_980496chr14_31014685_-ENSG00000181638.16ENST00000330701hsa-miR-624-3p1432600761432600827mer-m8143260063143260083143-18.66
CAediting_980496chr14_31014685_-ENSG00000181638.16ENST00000330701hsa-miR-624-3p1432601511432601577mer-m8143260138143260158143-18.66
CAediting_1306324chr19_13836464_-ENSG00000181638.16ENST00000330701hsa-miR-27a-3p1432626321432626387mer-m8143262619143262639153-16.71
CAediting_748296chr10_51299626_+ENSG00000264668.1ENST00000522452hsa-miR-605-3p1432509141432509207mer-m8143250903143250921142-22.43
CAediting_748296chr10_51299626_+ENSG00000264668.1ENST00000522452hsa-miR-605-3p1432511101432511167mer-m8143251094143251117146-23.23
CAediting_748296chr10_51299626_+ENSG00000264668.1ENST00000522452hsa-miR-605-3p1432512471432512537mer-m8143251233143251254147-18.49
CAediting_846604chr11_93733708_-ENSG00000264668.1ENST00000522452hsa-miR-1304-3p1432506051432506117mer-m8143250591143250612142-22.47
CAediting_846604chr11_93733708_-ENSG00000264668.1ENST00000522452hsa-miR-1304-3p1432509381432509447mer-m8143250923143250945159-27.03
CAediting_393chr1_1167164_+ENSG00000264668.1ENST00000522452hsa-miR-200b-3p1432513301432513367mer-m8143251315143251337153-16.83
CAediting_1054808chr15_66496985_-ENSG00000181638.16ENST00000520584hsa-miR-45121432508941432509018mer-1a143250878143250901145-17.16
CAediting_604450chr7_133034877_-ENSG00000181638.16ENST00000520584hsa-miR-36541432512641432512707mer-m8143251251143251271157-25.72
CAediting_1054808chr15_66496985_-ENSG00000181638.16ENST00000330701hsa-miR-45121432508941432509018mer-1a143250878143250901145-17.16
CAediting_604450chr7_133034877_-ENSG00000181638.16ENST00000330701hsa-miR-36541432512641432512707mer-m8143251251143251271157-25.72
CAediting_1229414chr17_67471546_+ENSG00000181638.16ENST00000330701hsa-miR-548aa1432623821432623887mer-m8143262368143262389158-16.71
CAediting_1160181chr17_7017644_-ENSG00000181638.16ENST00000330701hsa-miR-195-3p1432626851432626928mer-1a143262671143262692155-12.38
CAediting_524911chr7_5495852_-ENSG00000181638.16ENST00000330701hsa-miR-589-3p1432608891432608957mer-m8143260873143260896150-14.62
CAediting_524911chr7_5495852_-ENSG00000181638.16ENST00000330701hsa-miR-589-3p1432625671432625737mer-m8143262551143262574152-15.21
CAediting_1054808chr15_66496985_-ENSG00000264668.1ENST00000522452hsa-miR-45121432508941432509018mer-1a143250878143250901145-17.16
CAediting_604450chr7_133034877_-ENSG00000264668.1ENST00000522452hsa-miR-36541432512641432512707mer-m8143251251143251271157-25.72
CAediting_442554chr5_154685830_+ENSG00000264668.1ENST00000522452hsa-miR-13031432747521432747587mer-m8143274737143274759154-21.09
CAediting_1054808chr15_66496985_-ENSG00000264668.1ENST00000522452hsa-miR-45121432759411432759477mer-m8143275927143275948142-15.6

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_580943chr7_100356700_+ENSG00000181638.16ENST00000520584hsa-miR-6840-3p1432509461432509527mer-1a143250931143250952140-27.87
CAediting_580943chr7_100356700_+ENSG00000181638.16ENST00000330701hsa-miR-6840-3p1432509461432509527mer-1a143250931143250952140-27.87
CAediting_1054808chr15_66496985_-ENSG00000181638.16ENST00000330701hsa-miR-45121432613121432613176mer143261297143261318140-27.87
CAediting_1524209chrX_134546392_-ENSG00000181638.16ENST00000330701hsa-miR-503-5p1432616621432616687mer-m8143261643143261669147-20.53
CAediting_580943chr7_100356700_+ENSG00000181638.16ENST00000330701hsa-miR-6840-3p1432606061432606127mer-m8143260590143260613154-29.17
CAediting_468389chr6_31355314_-ENSG00000181638.16ENST00000330701hsa-miR-6891-5p1432610701432610767mer-m8143261059143261077145-20.77
CAediting_468389chr6_31355314_-ENSG00000181638.16ENST00000330701hsa-miR-6891-5p1432599341432599407mer-m8143259923143259941140-13.73
CAediting_580943chr7_100356700_+ENSG00000264668.1ENST00000522452hsa-miR-6840-3p1432509461432509527mer-1a143250931143250952140-27.87
CAediting_1524209chrX_134546392_-ENSG00000264668.1ENST00000522452hsa-miR-503-5p1432762591432762657mer-m8143276243143276266148-16.89

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZFP41

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ZFP41

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for ZFP41

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for ZFP41

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ZFP41

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZFP41

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource