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Editing gene: GAS2L3 (CAeditome ID:283431)

Gene summary for GAS2L3

Gene summary

Gene information	Gene symbol	GAS2L3
	Gene ID	283431
	Gene name	growth arrest specific 2 like 3
	Synonyms	G2L3
	Cytomap	12q23.1
	Type of gene	protein-coding
	Description	GAS2-like protein 3growth arrest-specific protein 2-like 3
	Modification date	20210518
	UniProtAcc	Q86XJ1
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
GAS2L3	GO:0003779	GAS2-like protein 3	21561867
GAS2L3	GO:0008017	GAS2-like protein 3	21561867
GAS2L3	GO:0000226	GAS2-like protein 3	21561867
GAS2L3	GO:0030036	GAS2-like protein 3	21561867
GAS2L3	GO:0015629	GAS2-like protein 3	21561867
GAS2L3	GO:0015630	GAS2-like protein 3	21561867

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RNA A-to-I events for GAS2L3

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000139354.9

RNA A-to-I editing events in Cancer.

CAediting_917717(100575581, +), CAediting_917718(100575582, +), CAediting_917719(100613791, +), CAediting_917720(100613793, +), CAediting_917721(100613801, +), CAediting_917722(100613805, +), CAediting_917723(100613846, +), CAediting_917724(100613874, +), CAediting_917725(100614202, +), CAediting_917726(100614208, +), CAediting_917727(100614209, +), CAediting_917728(100614299, +), CAediting_917729(100614307, +), CAediting_917730(100614316, +), CAediting_917731(100614342, +), CAediting_917732(100614356, +), CAediting_917733(100614395, +), CAediting_917734(100614412, +), CAediting_917735(100614418, +), CAediting_917736(100614428, +), CAediting_917737(100616458, +), CAediting_917738(100616489, +), CAediting_917739(100616492, +), CAediting_917740(100616578, +), CAediting_917741(100616638, +), CAediting_917742(100616677, +), CAediting_917743(100616684, +), CAediting_917744(100626822, +), CAediting_917745(100626832, +), CAediting_917746(100626836, +), CAediting_917747(100626837, +), CAediting_917748(100626842, +), CAediting_917749(100626845, +), CAediting_917750(100626854, +), CAediting_917751(100626858, +), CAediting_917752(100626859, +), CAediting_917753(100626867, +), CAediting_917754(100626872, +), CAediting_917755(100626875, +), CAediting_917756(100626876, +), CAediting_917757(100626880, +), CAediting_917758(100626883, +), CAediting_917759(100626889, +), CAediting_917760(100626890, +), CAediting_917761(100626891, +), CAediting_917762(100626894, +), CAediting_917763(100626900, +), CAediting_917764(100626903, +), CAediting_917765(100626904, +), CAediting_917766(100626906, +), CAediting_917767(100626912, +), CAediting_917768(100626913, +), CAediting_917769(100626914, +), CAediting_917770(100626925, +), CAediting_917771(100626928, +), CAediting_917772(100626929, +), CAediting_917773(100626930, +), CAediting_917774(100626931, +), CAediting_917775(100626932, +), CAediting_917776(100626934, +), CAediting_917777(100626937, +), CAediting_917778(100626942, +), CAediting_917779(100626950, +), CAediting_917780(100626966, +), CAediting_917781(100626968, +), CAediting_917782(100626969, +), CAediting_917783(100626974, +), CAediting_917784(100626982, +), CAediting_917785(100626991, +), CAediting_917786(100626995, +), CAediting_917787(100626998, +), CAediting_917788(100627009, +), CAediting_917789(100627010, +), CAediting_917790(100627021, +), CAediting_917791(100627030, +), CAediting_917792(100627034, +), CAediting_917793(100627039, +), CAediting_917794(100627041, +), CAediting_917795(100627069, +), CAediting_917796(100627293, +), CAediting_917797(100627305, +), CAediting_917798(100627318, +), CAediting_917799(100627320, +), CAediting_917800(100627330, +), CAediting_917801(100627336, +), CAediting_917802(100627338, +), CAediting_917803(100627344, +), CAediting_917804(100627349, +), CAediting_917805(100627354, +), CAediting_917806(100627355, +), CAediting_917807(100627374, +), CAediting_917808(100627379, +), CAediting_917809(100627392, +), CAediting_917810(100627401, +), CAediting_917811(100627414, +), CAediting_917812(100627416, +), CAediting_917813(100627420, +), CAediting_917814(100627436, +), CAediting_917815(100627440, +), CAediting_917816(100627441, +), CAediting_917817(100627451, +), CAediting_917818(100627457, +), CAediting_917819(100627462, +), CAediting_917820(100627464, +), CAediting_917821(100627478, +), CAediting_917822(100627487, +), CAediting_917823(100627498, +), CAediting_917824(100627499, +), CAediting_917825(100627500, +), CAediting_917826(100627507, +), CAediting_917827(100627512, +), CAediting_917828(100627517, +), CAediting_917829(100627521, +), CAediting_917830(100627530, +), CAediting_917831(100627539, +), CAediting_917832(100627540, +), CAediting_917833(100627552, +), CAediting_917834(100627570, +),

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RNA editing positional annotations for GAS2L3 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_917717	chr12_100575581_+	ncRNA_intronic
CAediting_917718	chr12_100575582_+	ncRNA_intronic
CAediting_917719	chr12_100613791_+	ncRNA_intronic
CAediting_917720	chr12_100613793_+	ncRNA_intronic
CAediting_917721	chr12_100613801_+	ncRNA_intronic
CAediting_917722	chr12_100613805_+	ncRNA_intronic
CAediting_917723	chr12_100613846_+	ncRNA_intronic
CAediting_917724	chr12_100613874_+	ncRNA_intronic
CAediting_917725	chr12_100614202_+	ncRNA_intronic
CAediting_917726	chr12_100614208_+	ncRNA_intronic
CAediting_917727	chr12_100614209_+	ncRNA_intronic
CAediting_917728	chr12_100614299_+	ncRNA_intronic
CAediting_917729	chr12_100614307_+	ncRNA_intronic
CAediting_917730	chr12_100614316_+	ncRNA_intronic
CAediting_917731	chr12_100614342_+	ncRNA_intronic
CAediting_917732	chr12_100614356_+	ncRNA_intronic
CAediting_917733	chr12_100614395_+	ncRNA_intronic
CAediting_917734	chr12_100614412_+	ncRNA_intronic
CAediting_917735	chr12_100614418_+	ncRNA_intronic
CAediting_917736	chr12_100614428_+	ncRNA_intronic
CAediting_917737	chr12_100616458_+	ncRNA_intronic
CAediting_917738	chr12_100616489_+	ncRNA_intronic
CAediting_917739	chr12_100616492_+	ncRNA_intronic
CAediting_917740	chr12_100616578_+	ncRNA_intronic
CAediting_917741	chr12_100616638_+	ncRNA_intronic
CAediting_917742	chr12_100616677_+	ncRNA_intronic
CAediting_917743	chr12_100616684_+	ncRNA_intronic
CAediting_917744	chr12_100626822_+	UTR3
CAediting_917745	chr12_100626832_+	UTR3
CAediting_917746	chr12_100626836_+	UTR3
CAediting_917747	chr12_100626837_+	UTR3
CAediting_917748	chr12_100626842_+	UTR3
CAediting_917749	chr12_100626845_+	UTR3
CAediting_917750	chr12_100626854_+	UTR3
CAediting_917751	chr12_100626858_+	UTR3
CAediting_917752	chr12_100626859_+	UTR3
CAediting_917753	chr12_100626867_+	intronic
CAediting_917754	chr12_100626872_+	intronic
CAediting_917755	chr12_100626875_+	intronic
CAediting_917756	chr12_100626876_+	intronic
CAediting_917757	chr12_100626880_+	intronic
CAediting_917758	chr12_100626883_+	intronic
CAediting_917759	chr12_100626889_+	intronic
CAediting_917760	chr12_100626890_+	intronic
CAediting_917761	chr12_100626891_+	intronic
CAediting_917762	chr12_100626894_+	intronic
CAediting_917763	chr12_100626900_+	intronic
CAediting_917764	chr12_100626903_+	intronic
CAediting_917765	chr12_100626904_+	intronic
CAediting_917766	chr12_100626906_+	intronic
CAediting_917767	chr12_100626912_+	intronic
CAediting_917768	chr12_100626913_+	intronic
CAediting_917769	chr12_100626914_+	intronic
CAediting_917770	chr12_100626925_+	intronic
CAediting_917771	chr12_100626928_+	intronic
CAediting_917772	chr12_100626929_+	intronic
CAediting_917773	chr12_100626930_+	intronic
CAediting_917774	chr12_100626931_+	intronic
CAediting_917775	chr12_100626932_+	intronic
CAediting_917776	chr12_100626934_+	intronic
CAediting_917777	chr12_100626937_+	intronic
CAediting_917778	chr12_100626942_+	intronic
CAediting_917779	chr12_100626950_+	intronic
CAediting_917780	chr12_100626966_+	intronic
CAediting_917781	chr12_100626968_+	intronic
CAediting_917782	chr12_100626969_+	intronic
CAediting_917783	chr12_100626974_+	intronic
CAediting_917784	chr12_100626982_+	intronic
CAediting_917785	chr12_100626991_+	intronic
CAediting_917786	chr12_100626995_+	intronic
CAediting_917787	chr12_100626998_+	intronic
CAediting_917788	chr12_100627009_+	intronic
CAediting_917789	chr12_100627010_+	intronic
CAediting_917790	chr12_100627021_+	intronic
CAediting_917791	chr12_100627030_+	intronic
CAediting_917792	chr12_100627034_+	intronic
CAediting_917793	chr12_100627039_+	intronic
CAediting_917794	chr12_100627041_+	intronic
CAediting_917795	chr12_100627069_+	intronic
CAediting_917796	chr12_100627293_+	intronic
CAediting_917797	chr12_100627305_+	intronic
CAediting_917798	chr12_100627318_+	intronic
CAediting_917799	chr12_100627320_+	intronic
CAediting_917800	chr12_100627330_+	intronic
CAediting_917801	chr12_100627336_+	intronic
CAediting_917802	chr12_100627338_+	intronic
CAediting_917803	chr12_100627344_+	intronic
CAediting_917804	chr12_100627349_+	intronic
CAediting_917805	chr12_100627354_+	intronic
CAediting_917806	chr12_100627355_+	intronic
CAediting_917807	chr12_100627374_+	intronic
CAediting_917808	chr12_100627379_+	intronic
CAediting_917809	chr12_100627392_+	intronic
CAediting_917810	chr12_100627401_+	intronic
CAediting_917811	chr12_100627414_+	intronic
CAediting_917812	chr12_100627416_+	intronic
CAediting_917813	chr12_100627420_+	intronic
CAediting_917814	chr12_100627436_+	intronic
CAediting_917815	chr12_100627440_+	intronic
CAediting_917816	chr12_100627441_+	intronic
CAediting_917817	chr12_100627451_+	intronic
CAediting_917818	chr12_100627457_+	intronic
CAediting_917819	chr12_100627462_+	intronic
CAediting_917820	chr12_100627464_+	intronic
CAediting_917821	chr12_100627478_+	intronic
CAediting_917822	chr12_100627487_+	splicing
CAediting_917823	chr12_100627498_+	UTR3
CAediting_917824	chr12_100627499_+	UTR3
CAediting_917825	chr12_100627500_+	UTR3
CAediting_917826	chr12_100627507_+	UTR3
CAediting_917827	chr12_100627512_+	UTR3
CAediting_917828	chr12_100627517_+	UTR3
CAediting_917829	chr12_100627521_+	UTR3
CAediting_917830	chr12_100627530_+	UTR3
CAediting_917831	chr12_100627539_+	UTR3
CAediting_917832	chr12_100627540_+	UTR3
CAediting_917833	chr12_100627552_+	UTR3
CAediting_917834	chr12_100627570_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_917717	chr12_100575581_+	SINE	Alu	AluSc
CAediting_917718	chr12_100575582_+	SINE	Alu	AluSc
CAediting_917719	chr12_100613791_+	SINE	Alu	AluYh3
CAediting_917720	chr12_100613793_+	SINE	Alu	AluYh3
CAediting_917721	chr12_100613801_+	SINE	Alu	AluYh3
CAediting_917722	chr12_100613805_+	SINE	Alu	AluYh3
CAediting_917723	chr12_100613846_+	SINE	Alu	AluYh3
CAediting_917724	chr12_100613874_+	SINE	Alu	AluYh3
CAediting_917725	chr12_100614202_+	SINE	Alu	AluSx
CAediting_917726	chr12_100614208_+	SINE	Alu	AluSx
CAediting_917727	chr12_100614209_+	SINE	Alu	AluSx
CAediting_917728	chr12_100614299_+	SINE	Alu	AluSx
CAediting_917729	chr12_100614307_+	SINE	Alu	AluSx
CAediting_917730	chr12_100614316_+	SINE	Alu	AluSx
CAediting_917731	chr12_100614342_+	SINE	Alu	AluSx
CAediting_917732	chr12_100614356_+	SINE	Alu	AluSx
CAediting_917733	chr12_100614395_+	SINE	Alu	AluSx
CAediting_917734	chr12_100614412_+	SINE	Alu	AluSx
CAediting_917735	chr12_100614418_+	SINE	Alu	AluSx
CAediting_917736	chr12_100614428_+	SINE	Alu	AluSx
CAediting_917737	chr12_100616458_+	SINE	Alu	AluJr4
CAediting_917738	chr12_100616489_+	SINE	Alu	AluJr4
CAediting_917739	chr12_100616492_+	SINE	Alu	AluJr4
CAediting_917740	chr12_100616578_+	SINE	Alu	AluJr4
CAediting_917741	chr12_100616638_+	SINE	Alu	AluJr4
CAediting_917742	chr12_100616677_+	SINE	Alu	AluJr4
CAediting_917743	chr12_100616684_+	SINE	Alu	AluJr4
CAediting_917746	chr12_100626836_+	SINE	Alu	AluSg
CAediting_917747	chr12_100626837_+	SINE	Alu	AluSg
CAediting_917748	chr12_100626842_+	SINE	Alu	AluSg
CAediting_917749	chr12_100626845_+	SINE	Alu	AluSg
CAediting_917750	chr12_100626854_+	SINE	Alu	AluSg
CAediting_917751	chr12_100626858_+	SINE	Alu	AluSg
CAediting_917752	chr12_100626859_+	SINE	Alu	AluSg
CAediting_917753	chr12_100626867_+	SINE	Alu	AluSg
CAediting_917754	chr12_100626872_+	SINE	Alu	AluSg
CAediting_917755	chr12_100626875_+	SINE	Alu	AluSg
CAediting_917756	chr12_100626876_+	SINE	Alu	AluSg
CAediting_917757	chr12_100626880_+	SINE	Alu	AluSg
CAediting_917758	chr12_100626883_+	SINE	Alu	AluSg
CAediting_917759	chr12_100626889_+	SINE	Alu	AluSg
CAediting_917760	chr12_100626890_+	SINE	Alu	AluSg
CAediting_917761	chr12_100626891_+	SINE	Alu	AluSg
CAediting_917762	chr12_100626894_+	SINE	Alu	AluSg
CAediting_917763	chr12_100626900_+	SINE	Alu	AluSg
CAediting_917764	chr12_100626903_+	SINE	Alu	AluSg
CAediting_917765	chr12_100626904_+	SINE	Alu	AluSg
CAediting_917766	chr12_100626906_+	SINE	Alu	AluSg
CAediting_917767	chr12_100626912_+	SINE	Alu	AluSg
CAediting_917768	chr12_100626913_+	SINE	Alu	AluSg
CAediting_917769	chr12_100626914_+	SINE	Alu	AluSg
CAediting_917770	chr12_100626925_+	SINE	Alu	AluSg
CAediting_917771	chr12_100626928_+	SINE	Alu	AluSg
CAediting_917772	chr12_100626929_+	SINE	Alu	AluSg
CAediting_917773	chr12_100626930_+	SINE	Alu	AluSg
CAediting_917774	chr12_100626931_+	SINE	Alu	AluSg
CAediting_917775	chr12_100626932_+	SINE	Alu	AluSg
CAediting_917776	chr12_100626934_+	SINE	Alu	AluSg
CAediting_917777	chr12_100626937_+	SINE	Alu	AluSg
CAediting_917778	chr12_100626942_+	SINE	Alu	AluSg
CAediting_917779	chr12_100626950_+	SINE	Alu	AluSg
CAediting_917780	chr12_100626966_+	SINE	Alu	AluSg
CAediting_917781	chr12_100626968_+	SINE	Alu	AluSg
CAediting_917782	chr12_100626969_+	SINE	Alu	AluSg
CAediting_917783	chr12_100626974_+	SINE	Alu	AluSg
CAediting_917784	chr12_100626982_+	SINE	Alu	AluSg
CAediting_917785	chr12_100626991_+	SINE	Alu	AluSg
CAediting_917786	chr12_100626995_+	SINE	Alu	AluSg
CAediting_917787	chr12_100626998_+	SINE	Alu	AluSg
CAediting_917788	chr12_100627009_+	SINE	Alu	AluSg
CAediting_917789	chr12_100627010_+	SINE	Alu	AluSg
CAediting_917790	chr12_100627021_+	SINE	Alu	AluSg
CAediting_917791	chr12_100627030_+	SINE	Alu	AluSg
CAediting_917792	chr12_100627034_+	SINE	Alu	AluSg
CAediting_917793	chr12_100627039_+	SINE	Alu	AluSg
CAediting_917794	chr12_100627041_+	SINE	Alu	AluSg
CAediting_917795	chr12_100627069_+	SINE	Alu	AluSg
CAediting_917796	chr12_100627293_+	SINE	Alu	AluSq
CAediting_917797	chr12_100627305_+	SINE	Alu	AluSq
CAediting_917798	chr12_100627318_+	SINE	Alu	AluSq
CAediting_917799	chr12_100627320_+	SINE	Alu	AluSq
CAediting_917800	chr12_100627330_+	SINE	Alu	AluSq
CAediting_917801	chr12_100627336_+	SINE	Alu	AluSq
CAediting_917802	chr12_100627338_+	SINE	Alu	AluSq
CAediting_917803	chr12_100627344_+	SINE	Alu	AluSq
CAediting_917804	chr12_100627349_+	SINE	Alu	AluSq
CAediting_917805	chr12_100627354_+	SINE	Alu	AluSq
CAediting_917806	chr12_100627355_+	SINE	Alu	AluSq
CAediting_917807	chr12_100627374_+	SINE	Alu	AluSq
CAediting_917808	chr12_100627379_+	SINE	Alu	AluSq
CAediting_917809	chr12_100627392_+	SINE	Alu	AluSq
CAediting_917810	chr12_100627401_+	SINE	Alu	AluSq
CAediting_917811	chr12_100627414_+	SINE	Alu	AluSq
CAediting_917812	chr12_100627416_+	SINE	Alu	AluSq
CAediting_917813	chr12_100627420_+	SINE	Alu	AluSq
CAediting_917814	chr12_100627436_+	SINE	Alu	AluSq
CAediting_917815	chr12_100627440_+	SINE	Alu	AluSq
CAediting_917816	chr12_100627441_+	SINE	Alu	AluSq
CAediting_917817	chr12_100627451_+	SINE	Alu	AluSq
CAediting_917818	chr12_100627457_+	SINE	Alu	AluSq
CAediting_917819	chr12_100627462_+	SINE	Alu	AluSq
CAediting_917820	chr12_100627464_+	SINE	Alu	AluSq
CAediting_917821	chr12_100627478_+	SINE	Alu	AluSq
CAediting_917822	chr12_100627487_+	SINE	Alu	AluSq
CAediting_917823	chr12_100627498_+	SINE	Alu	AluSq
CAediting_917824	chr12_100627499_+	SINE	Alu	AluSq
CAediting_917825	chr12_100627500_+	SINE	Alu	AluSq
CAediting_917826	chr12_100627507_+	SINE	Alu	AluSq
CAediting_917827	chr12_100627512_+	SINE	Alu	AluSq
CAediting_917828	chr12_100627517_+	SINE	Alu	AluSq
CAediting_917829	chr12_100627521_+	SINE	Alu	AluSq
CAediting_917830	chr12_100627530_+	SINE	Alu	AluSq
CAediting_917831	chr12_100627539_+	SINE	Alu	AluSq
CAediting_917832	chr12_100627540_+	SINE	Alu	AluSq
CAediting_917833	chr12_100627552_+	SINE	Alu	AluSq
CAediting_917834	chr12_100627570_+	SINE	Alu	AluSq

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RNA A-to-I editing events in the alternative splicing sites for GAS2L3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_917753	chr12_100626867_+	100626862:100626870	5SS	0+3i	TGGGCAGAT	-7.38	TGGGCGGAT	-12.4
IR	CAediting_917821	chr12_100627478_+	100627468:100627490	3SS	0+10i	GGGTTTCACCATGTCGGCCAGGC	-12.84	GGGTTTCACCGTGTCGGCCAGGC	-11.74
IR	CAediting_917822	chr12_100627487_+	100627468:100627490	3SS	0+1i	GGGTTTCACCATGTCGGCCAGGC	-12.84	GGGTTTCACCATGTCGGCCGGGC	-4.09

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000139354.9.GAS2L3.

Correlation between RNA A-to-I editing and PSI for ENSG00000139354.9.GAS2L3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GAS2L3

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BRCA.CAediting_917811.ENSG00000139354.GAS2L3.png
Soverview

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Protein coding region RNA A-to-I editings for GAS2L3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for GAS2L3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_917747	chr12_100626837_+	ENSG00000139354.9	ENST00000552854	hsa-miR-1288-3p	100626833	100626839	7mer-m8	100626821	100626840	157.00	-22.92
CAediting_917747	chr12_100626837_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3199	100626834	100626841	8mer-1a	100626819	100626841	155.00	-23.78
CAediting_917747	chr12_100626837_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3199	100626834	100626841	8mer-1a	100626819	100626841	155.00	-23.78
CAediting_917747	chr12_100626837_+	ENSG00000139354.9	ENST00000552854	hsa-miR-5002-3p	100626832	100626838	7mer-m8	100626819	100626839	145.00	-14.80
CAediting_917747	chr12_100626837_+	ENSG00000139354.9	ENST00000552854	hsa-miR-8052	100626834	100626841	8mer-1a	100626821	100626841	142.00	-19.92
CAediting_917750	chr12_100626854_+	ENSG00000139354.9	ENST00000552854	hsa-miR-150-5p	100626847	100626853	7mer-m8	100626833	100626854	140.00	-14.00
CAediting_917750	chr12_100626854_+	ENSG00000139354.9	ENST00000552854	hsa-miR-6778-3p	100626849	100626855	7mer-m8	100626837	100626856	146.00	-13.66
CAediting_917750	chr12_100626854_+	ENSG00000139354.9	ENST00000552854	hsa-miR-6878-3p	100626851	100626858	8mer-1a	100626838	100626858	142.00	-14.14
CAediting_917751	chr12_100626858_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4638-5p	100626853	100626859	7mer-m8	100626840	100626860	142.00	-16.92
CAediting_917744	chr12_100626822_+	ENSG00000139354.9	ENST00000552854	hsa-miR-495-3p	100626817	100626823	7mer-m8	100626803	100626824	145.00	-10.76
CAediting_917744	chr12_100626822_+	ENSG00000139354.9	ENST00000552854	hsa-miR-5688	100626817	100626823	7mer-m8	100626803	100626824	146.00	-9.66
CAediting_917746	chr12_100626836_+	ENSG00000139354.9	ENST00000552854	hsa-miR-638	100626834	100626841	8mer-1a	100626816	100626841	148.00	-24.50
CAediting_917752	chr12_100626859_+	ENSG00000139354.9	ENST00000552854	hsa-miR-490-3p	100626855	100626861	7mer-m8	100626841	100626862	140.00	-22.71
CAediting_917829	chr12_100627521_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3937	100627518	100627524	7mer-m8	100627506	100627525	144.00	-23.68
CAediting_917832	chr12_100627540_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3189-3p	100627534	100627540	7mer-m8	100627518	100627541	153.00	-26.41
CAediting_917834	chr12_100627570_+	ENSG00000139354.9	ENST00000552854	hsa-miR-1268a	100627566	100627573	8mer-1a	100627556	100627573	157.00	-24.37
CAediting_917834	chr12_100627570_+	ENSG00000139354.9	ENST00000552854	hsa-miR-1268b	100627566	100627573	8mer-1a	100627554	100627573	157.00	-26.26
CAediting_917834	chr12_100627570_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4486	100627568	100627574	7mer-m8	100627560	100627575	149.00	-26.24
CAediting_917828	chr12_100627517_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4776-5p	100627514	100627520	7mer-m8	100627498	100627521	151.00	-24.89
CAediting_917828	chr12_100627517_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4776-5p	100627514	100627520	7mer-m8	100627498	100627521	151.00	-24.89
CAediting_917828	chr12_100627517_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4800-5p	100627515	100627521	7mer-m8	100627497	100627522	147.00	-24.71
CAediting_917831	chr12_100627539_+	ENSG00000139354.9	ENST00000552854	hsa-miR-326	100627534	100627540	7mer-m8	100627522	100627541	140.00	-14.01
CAediting_917831	chr12_100627539_+	ENSG00000139354.9	ENST00000552854	hsa-miR-330-5p	100627534	100627540	7mer-m8	100627518	100627541	143.00	-21.97
CAediting_917831	chr12_100627539_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4314	100627533	100627539	7mer-m8	100627522	100627540	143.00	-24.03

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_917745	chr12_100626832_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3176	100626826	100626832	7mer-m8	100626815	100626833	145	-14.99
CAediting_917749	chr12_100626845_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4698	100626843	100626849	7mer-m8	100626829	100626850	150	-15.06
CAediting_917747	chr12_100626837_+	ENSG00000139354.9	ENST00000552854	hsa-miR-5089-5p	100626835	100626841	7mer-m8	100626822	100626842	148	-17.04
CAediting_917748	chr12_100626842_+	ENSG00000139354.9	ENST00000552854	hsa-miR-5089-5p	100626835	100626841	7mer-m8	100626822	100626842	148	-17.04
CAediting_917748	chr12_100626842_+	ENSG00000139354.9	ENST00000552854	hsa-miR-619-5p	100626836	100626842	7mer-m8	100626821	100626843	155	-22.18
CAediting_917748	chr12_100626842_+	ENSG00000139354.9	ENST00000552854	hsa-miR-6506-5p	100626836	100626842	7mer-m8	100626822	100626843	145	-16.52
CAediting_917745	chr12_100626832_+	ENSG00000139354.9	ENST00000552854	hsa-miR-6878-3p	100626825	100626831	7mer-m8	100626812	100626832	140	-16.33
CAediting_917829	chr12_100627521_+	ENSG00000139354.9	ENST00000552854	hsa-miR-12114	100627517	100627523	7mer-m8	100627505	100627524	152	-28.83
CAediting_917829	chr12_100627521_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3165	100627516	100627522	7mer-m8	100627504	100627523	145	-17.91
CAediting_917827	chr12_100627512_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3622a-3p	100627509	100627516	8mer-1a	100627495	100627516	144	-13.56
CAediting_917827	chr12_100627512_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3622b-3p	100627509	100627516	8mer-1a	100627496	100627516	153	-19.33
CAediting_917829	chr12_100627521_+	ENSG00000139354.9	ENST00000552854	hsa-miR-3665	100627519	100627525	7mer-m8	100627509	100627526	140	-17.7
CAediting_917834	chr12_100627570_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4455	100627566	100627573	8mer-1a	100627558	100627573	145	-16.11
CAediting_917830	chr12_100627530_+	ENSG00000139354.9	ENST00000552854	hsa-miR-4478	100627527	100627533	7mer-m8	100627519	100627534	149	-22.24
CAediting_917830	chr12_100627530_+	ENSG00000139354.9	ENST00000552854	hsa-miR-485-5p	100627528	100627534	7mer-m8	100627514	100627535	149	-16.01
CAediting_917834	chr12_100627570_+	ENSG00000139354.9	ENST00000552854	hsa-miR-6776-5p	100627568	100627574	7mer-m8	100627557	100627575	150	-19.66
CAediting_917830	chr12_100627530_+	ENSG00000139354.9	ENST00000552854	hsa-miR-7160-5p	100627525	100627531	7mer-m8	100627515	100627532	144	-18.41
CAediting_917827	chr12_100627512_+	ENSG00000139354.9	ENST00000552854	hsa-miR-7162-3p	100627506	100627512	7mer-m8	100627493	100627513	142	-17.47
CAediting_917828	chr12_100627517_+	ENSG00000139354.9	ENST00000552854	hsa-miR-8056	100627516	100627521	6mer	100627503	100627522	142	-18.58
CAediting_917829	chr12_100627521_+	ENSG00000139354.9	ENST00000552854	hsa-miR-8056	100627516	100627521	6mer	100627503	100627522	142	-18.58
CAediting_917831	chr12_100627539_+	ENSG00000139354.9	ENST00000552854	hsa-miR-887-5p	100627532	100627539	8mer-1a	100627520	100627539	143	-15.14

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000139354.9	ENST00000552854	hsa-miR-200b-3p	100626840	100626846	7mer-m8	100626826	100626847	140	-17.33
CAediting_1160181	chr17_7017644_-	ENSG00000139354.9	ENST00000552854	hsa-miR-195-3p	100627694	100627700	7mer-m8	100627682	100627701	153	-14.72

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000139354.9	ENST00000552854	hsa-miR-200b-3p	100626147	100626153	7mer-m8	100626133	100626154	147	-10.3
CAediting_393	chr1_1167164_+	ENSG00000139354.9	ENST00000552854	hsa-miR-200b-3p	100626174	100626180	7mer-m8	100626159	100626181	149	-11.17

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GAS2L3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for GAS2L3

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BLCA	CAediting_917760	chr12_100626890_+	0.0395466416206811	0.221147520138431	0.00829142468787671	0.281361388762533	.	.
BRCA	CAediting_917760	chr12_100626890_+	4.5941202311732e-05	0.231883415225936	.	.	.	.
CESC	CAediting_917760	chr12_100626890_+	0.0450196543977132	0.170928766538538	.	.	.	.
COAD	CAediting_917760	chr12_100626890_+	0.0404578350813357	0.135818303012346	.	.	.	.
GBM	CAediting_917760	chr12_100626890_+	0.000700549357918343	0.289222573627369	.	.	.	.
OV	CAediting_917760	chr12_100626890_+	0.000540051375593532	0.312499611827361	.	.	.	.
SKCM	CAediting_917760	chr12_100626890_+	4.49539302514161e-06	0.228748197881207	.	.	.	.
READ	CAediting_917760	chr12_100626890_+	0.0062924980092385	0.343352466809825	.	.	.	.
SARC	CAediting_917760	chr12_100626890_+	5.78223176306126e-06	0.371405290281264	.	.	.	.
BRCA	CAediting_917761	chr12_100626891_+	0.00311971754379359	0.350847380322916	.	.	.	.
BRCA	CAediting_917764	chr12_100626903_+	0.00296533236685029	0.202196602179213	.	.	.	.
COAD	CAediting_917764	chr12_100626903_+	.	.	.	.	0.0169998506669257	0.190257400492097
LUSC	CAediting_917764	chr12_100626903_+	0.0423344238683167	0.250686458268123	.	.	.	.
GBM	CAediting_917764	chr12_100626903_+	0.000171895030508511	0.360313853362176	0.0272546097114978	0.216539275303815	.	.
KIRP	CAediting_917764	chr12_100626903_+	0.0321781582162418	0.205359984628178	.	.	.	.
ESCA	CAediting_917764	chr12_100626903_+	.	.	0.00140179824574169	0.357745700955272	.	.
OV	CAediting_917764	chr12_100626903_+	0.0480297571649651	0.213852753252838	.	.	.	.
SKCM	CAediting_917764	chr12_100626903_+	0.0125066781130869	0.136939179245246	.	.	.	.
SARC	CAediting_917764	chr12_100626903_+	0.0129301347539097	0.224474722139309	.	.	.	.
SKCM	CAediting_917770	chr12_100626925_+	0.0455028911305812	0.15885318320202	.	.	0.0325233174242341	0.169655547955339
BRCA	CAediting_917771	chr12_100626928_+	0.0121325597027544	0.217761086016224	.	.	.	.
CESC	CAediting_917771	chr12_100626928_+	0.00826791173222643	0.340754148219522	.	.	.	.
GBM	CAediting_917771	chr12_100626928_+	5.29949154325869e-06	0.461559198807669	.	.	.	.
STAD	CAediting_917771	chr12_100626928_+	0.0289843396870475	0.232901984222175	.	.	.	.
ESCA	CAediting_917771	chr12_100626928_+	.	.	0.000689817410660942	0.459693560259092	.	.
SKCM	CAediting_917771	chr12_100626928_+	1.06348120675509e-08	0.320695937543404	.	.	.	.
SKCM	CAediting_917780	chr12_100626966_+	0.0361790678030413	0.223678412744291	.	.	.	.
STAD	CAediting_917781	chr12_100626968_+	0.0476983115077014	0.281450535359804	.	.	.	.
SKCM	CAediting_917781	chr12_100626968_+	0.0383158674281633	0.225121748613283	0.0025250267741832	0.323531668247209	.	.
BRCA	CAediting_917801	chr12_100627336_+	0.0123839039448846	0.313391847847455	.	.	.	.
GBM	CAediting_917801	chr12_100627336_+	0.00496018951180701	0.373604700714486	.	.	.	.
SKCM	CAediting_917801	chr12_100627336_+	0.00932159134131954	0.289009061682135	.	.	0.0223522730713135	0.255168025853149
GBM	CAediting_917803	chr12_100627344_+	0.0134047706470325	0.294281953999535	.	.	.	.
SKCM	CAediting_917803	chr12_100627344_+	7.24721911466017e-05	0.354125231408428	.	.	.	.
KIRC	CAediting_917807	chr12_100627374_+	4.25364949266494e-05	0.264228217043775	.	.	.	.
SKCM	CAediting_917807	chr12_100627374_+	3.24049754771663e-08	0.346097409941399	.	.	.	.
KIRC	CAediting_917808	chr12_100627379_+	0.0393361396654349	0.212945052961084	.	.	.	.
SKCM	CAediting_917808	chr12_100627379_+	0.00997435334061901	0.319883115751316	.	.	.	.
BLCA	CAediting_917811	chr12_100627414_+	0.0238109556246549	0.246479644701205	.	.	.	.
BRCA	CAediting_917811	chr12_100627414_+	0.0021097181100561	0.220006870919908	.	.	.	.
CESC	CAediting_917811	chr12_100627414_+	4.27121812166593e-06	0.393710812268844	.	.	.	.
COAD	CAediting_917811	chr12_100627414_+	0.00461700140926939	0.224253378572563	.	.	.	.
GBM	CAediting_917811	chr12_100627414_+	1.18382503681429e-05	0.39925480914682	.	.	.	.
KIRC	CAediting_917811	chr12_100627414_+	0.00751646425312559	0.130109211243146	.	.	.	.
UCEC	CAediting_917811	chr12_100627414_+	0.000281756405190756	0.368229013541611	.	.	.	.
ESCA	CAediting_917811	chr12_100627414_+	.	.	0.0254843367898913	0.261414872738275	.	.
SKCM	CAediting_917811	chr12_100627414_+	2.95527725404248e-20	0.44852666254074	.	.	.	.
SARC	CAediting_917811	chr12_100627414_+	2.84267560874626e-07	0.410895830884686	.	.	.	.
COAD	CAediting_917812	chr12_100627416_+	0.0203857790732201	0.230518279167933	.	.	.	.
GBM	CAediting_917812	chr12_100627416_+	0.0257024147122368	0.252542761013578	0.0321547083934026	0.242864732426314	.	.
SKCM	CAediting_917812	chr12_100627416_+	0.000694383707177121	0.200808675386495	.	.	.	.
BLCA	CAediting_917818	chr12_100627457_+	0.00419702310321634	0.32694069112689	.	.	.	.
BRCA	CAediting_917818	chr12_100627457_+	1.82434866619782e-07	0.311549476116078	.	.	.	.
LIHC	CAediting_917818	chr12_100627457_+	0.00104025199999192	0.409760549307721	.	.	.	.
CESC	CAediting_917818	chr12_100627457_+	0.03439080287393	0.200110526403257	.	.	0.00732054505291947	0.252136255637134
COAD	CAediting_917818	chr12_100627457_+	6.47571305112155e-06	0.475112580369222	0.0103819663775907	0.281589531765005	.	.
GBM	CAediting_917818	chr12_100627457_+	7.02229543532244e-06	0.556294316253025	.	.	.	.
STAD	CAediting_917818	chr12_100627457_+	0.0210641207552793	0.210423032872625	.	.	.	.
UCEC	CAediting_917818	chr12_100627457_+	0.00238249300038094	0.370484095255584	.	.	.	.
KIRP	CAediting_917818	chr12_100627457_+	0.0483353029493767	0.262723380779637	.	.	.	.
ESCA	CAediting_917818	chr12_100627457_+	0.0103242343244468	0.343145612399005	.	.	.	.
OV	CAediting_917818	chr12_100627457_+	0.0188162397025995	0.177947591516202	.	.	.	.
SKCM	CAediting_917818	chr12_100627457_+	6.37772078834714e-07	0.341858708769346	.	.	.	.
SARC	CAediting_917818	chr12_100627457_+	3.42154584178724e-06	0.426315139719032	.	.	.	.
STAD	CAediting_917822	chr12_100627487_+	0.00351031009820898	0.324654550086824	.	.	.	.
SKCM	CAediting_917822	chr12_100627487_+	.	.	0.000189574872284357	0.403236974828754	.	.
GBM	CAediting_917823	chr12_100627498_+	1.80681065888877e-05	0.380547751586532	.	.	.	.
STAD	CAediting_917823	chr12_100627498_+	0.0110792502696124	0.176238424631612	0.0158943028604575	0.167428355735086	.	.
OV	CAediting_917823	chr12_100627498_+	0.0126072089811129	0.152778916944988	.	.	.	.
SKCM	CAediting_917823	chr12_100627498_+	.	.	0.000329455284130055	0.376189041826833	.	.

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Relation with cancer stages for GAS2L3

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_917760	chr12_100626890_+	0.0391213326946621	0.224216258108813
BRCA	pathologic_stage	CAediting_917770	chr12_100626925_+	0.0139367586483021	0.329797590906226
CESC	clinical_stage	CAediting_917812	chr12_100627416_+	0.00935945084072223	-0.275570169922017
COAD	pathologic_stage	CAediting_917760	chr12_100626890_+	0.0113691855188008	0.169604037961224
HNSC	clinical_stage	CAediting_917760	chr12_100626890_+	0.0417563378321427	-0.268250130584348
KIRC	pathologic_stage	CAediting_917750	chr12_100626854_+	0.00470452368464085	0.341312020286755
KIRC	pathologic_stage	CAediting_917751	chr12_100626858_+	0.0330316440715486	0.253339961090572
KIRC	pathologic_stage	CAediting_917760	chr12_100626890_+	0.0147926594536086	0.115095694600536
KIRC	pathologic_stage	CAediting_917761	chr12_100626891_+	0.0327187562892645	0.214843150148302
KIRC	pathologic_stage	CAediting_917763	chr12_100626900_+	0.00223760430987115	0.291123572019119
KIRC	pathologic_stage	CAediting_917764	chr12_100626903_+	1.72349704208905e-05	0.206833896320907
KIRC	pathologic_stage	CAediting_917765	chr12_100626904_+	0.00619124059357992	0.278953882309616
KIRC	pathologic_stage	CAediting_917771	chr12_100626928_+	0.00147552114655861	0.166974793182897
KIRC	pathologic_stage	CAediting_917781	chr12_100626968_+	0.0258905514335479	0.214370693332135
KIRC	pathologic_stage	CAediting_917811	chr12_100627414_+	0.0452800332149152	0.0978637076449725
KIRC	pathologic_stage	CAediting_917814	chr12_100627436_+	0.00702961949729652	0.324008439571785
KIRC	pathologic_stage	CAediting_917818	chr12_100627457_+	0.0109814375504534	0.14156798920661
KIRP	pathologic_stage	CAediting_917760	chr12_100626890_+	0.00449518918785561	0.25980726591771
KIRP	pathologic_stage	CAediting_917811	chr12_100627414_+	0.0483386872861207	0.194104239809813
STAD	pathologic_stage	CAediting_917763	chr12_100626900_+	0.0139736533975932	-0.335765356209843
STAD	pathologic_stage	CAediting_917814	chr12_100627436_+	0.0342674084008957	-0.286020836791359
UCEC	clinical_stage	CAediting_917760	chr12_100626890_+	0.0473357525878782	-0.219705967017004

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Relation with survival for GAS2L3

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
BRCA	CAediting_917771	chr12_100626928_+	0.023885437254055	0.0450169	0.0124719
LIHC	CAediting_917818	chr12_100627457_+	0.0298531235006276	0.00074849	1325.47
KIRC	CAediting_917781	chr12_100626968_+	0.0106739894327201	0.0239073	40.4003
KIRP	CAediting_917812	chr12_100627416_+	0.00267700056903031	0.00300099	9866000
OV	CAediting_917818	chr12_100627457_+	0.0238466017304235	0.0232065	10.5707

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RelatedDrugs for GAS2L3

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for GAS2L3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene