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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: GNAL (CAeditome ID:2774)

Gene summary for GNAL

check button Gene summary
Gene informationGene symbol

GNAL

Gene ID

2774

Gene nameG protein subunit alpha L
SynonymsDYT25
Cytomap

18p11.21

Type of geneprotein-coding
Descriptionguanine nucleotide-binding protein G(olf) subunit alphaadenylate cyclase-stimulating G alpha protein, olfactory typeguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory typeguanine nucleotide binding protein
Modification date20210518
UniProtAcc

P38405

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for GNAL

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000141404.14
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1253361(11763557, +), CAediting_1253362(11763560, +), CAediting_1253363(11764345, +), CAediting_1253364(11764618, +), CAediting_1253365(11771050, +), CAediting_1253366(11771973, +), CAediting_1253367(11778937, +), CAediting_1253368(11795199, +), CAediting_1253369(11795254, +), CAediting_1253370(11795267, +), CAediting_1253371(11795280, +), CAediting_1253372(11795290, +), CAediting_1253373(11795370, +), CAediting_1253374(11796306, +), CAediting_1253375(11796322, +), CAediting_1253376(11796323, +), CAediting_1253377(11796328, +), CAediting_1253378(11796345, +), CAediting_1253379(11796358, +), CAediting_1253380(11796361, +), CAediting_1253381(11796377, +), CAediting_1253382(11796380, +), CAediting_1253383(11796389, +), CAediting_1253384(11796390, +), CAediting_1253385(11796400, +), CAediting_1253386(11796411, +), CAediting_1253387(11797116, +), CAediting_1253388(11797117, +), CAediting_1253389(11797480, +), CAediting_1253390(11810211, +), CAediting_1253391(11816694, +), CAediting_1253392(11817772, +), CAediting_1253393(11832596, +), CAediting_1253394(11832766, +), CAediting_1253395(11833144, +), CAediting_1253396(11833197, +), CAediting_1253397(11833198, +), CAediting_1253398(11833212, +), CAediting_1253399(11833222, +), CAediting_1253400(11834597, +), CAediting_1253401(11837040, +), CAediting_1253402(11839288, +), CAediting_1253403(11839405, +), CAediting_1253404(11839479, +), CAediting_1253405(11839497, +), CAediting_1253406(11840906, +), CAediting_1253407(11840967, +), CAediting_1253408(11840985, +), CAediting_1253409(11841007, +), CAediting_1253410(11841038, +), CAediting_1253411(11841048, +), CAediting_1253412(11841388, +), CAediting_1253413(11841391, +), CAediting_1253414(11841426, +), CAediting_1253415(11841436, +), CAediting_1253416(11841445, +), CAediting_1253417(11841470, +), CAediting_1253418(11841524, +), CAediting_1253419(11841546, +), CAediting_1253420(11841547, +), CAediting_1253421(11841551, +), CAediting_1253422(11841565, +), CAediting_1253423(11841566, +), CAediting_1253424(11841632, +), CAediting_1253425(11843405, +), CAediting_1253426(11848582, +), CAediting_1253427(11848583, +), CAediting_1253428(11848725, +), CAediting_1253429(11849295, +), CAediting_1253430(11849331, +), CAediting_1253431(11849457, +), CAediting_1253432(11849459, +), CAediting_1253433(11849530, +), CAediting_1253434(11853175, +), CAediting_1253435(11853176, +), CAediting_1253436(11853940, +), CAediting_1253437(11853952, +), CAediting_1253438(11853962, +), CAediting_1253439(11853975, +), CAediting_1253440(11854944, +), CAediting_1253441(11854985, +), CAediting_1253442(11856811, +), CAediting_1253443(11878330, +), CAediting_1253444(11878639, +), CAediting_1253445(11878699, +), CAediting_1253446(11878709, +), CAediting_1253447(11878715, +), CAediting_1253448(11878790, +), CAediting_1253449(11878803, +), CAediting_1253450(11882424, +), CAediting_1253451(11882432, +), CAediting_1253452(11882433, +), CAediting_1253453(11882438, +), CAediting_1253454(11882468, +), CAediting_1253455(11882484, +), CAediting_1253456(11882485, +), CAediting_1253457(11882487, +), CAediting_1253458(11882500, +), CAediting_1253459(11882528, +), CAediting_1253460(11882530, +), CAediting_1253461(11882533, +), CAediting_1253462(11882536, +), CAediting_1253463(11882539, +), CAediting_1253464(11882543, +), CAediting_1253465(11882559, +), CAediting_1253466(11882575, +), CAediting_1253467(11882588, +), CAediting_1253468(11882592, +), CAediting_1253469(11882598, +), CAediting_1253470(11882607, +), CAediting_1253471(11882614, +),

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RNA editing positional annotations for GNAL using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1253361chr18_11763557_+ncRNA_intronic
CAediting_1253362chr18_11763560_+ncRNA_intronic
CAediting_1253363chr18_11764345_+ncRNA_intronic
CAediting_1253364chr18_11764618_+ncRNA_intronic
CAediting_1253365chr18_11771050_+ncRNA_intronic
CAediting_1253366chr18_11771973_+ncRNA_intronic
CAediting_1253367chr18_11778937_+ncRNA_intronic
CAediting_1253368chr18_11795199_+ncRNA_intronic
CAediting_1253369chr18_11795254_+ncRNA_intronic
CAediting_1253370chr18_11795267_+ncRNA_intronic
CAediting_1253371chr18_11795280_+ncRNA_intronic
CAediting_1253372chr18_11795290_+ncRNA_intronic
CAediting_1253373chr18_11795370_+ncRNA_intronic
CAediting_1253374chr18_11796306_+ncRNA_intronic
CAediting_1253375chr18_11796322_+ncRNA_intronic
CAediting_1253376chr18_11796323_+ncRNA_intronic
CAediting_1253377chr18_11796328_+ncRNA_intronic
CAediting_1253378chr18_11796345_+ncRNA_intronic
CAediting_1253379chr18_11796358_+ncRNA_intronic
CAediting_1253380chr18_11796361_+ncRNA_intronic
CAediting_1253381chr18_11796377_+ncRNA_intronic
CAediting_1253382chr18_11796380_+ncRNA_intronic
CAediting_1253383chr18_11796389_+ncRNA_intronic
CAediting_1253384chr18_11796390_+ncRNA_intronic
CAediting_1253385chr18_11796400_+ncRNA_intronic
CAediting_1253386chr18_11796411_+ncRNA_intronic
CAediting_1253387chr18_11797116_+ncRNA_intronic
CAediting_1253388chr18_11797117_+ncRNA_intronic
CAediting_1253389chr18_11797480_+ncRNA_intronic
CAediting_1253390chr18_11810211_+ncRNA_intronic
CAediting_1253391chr18_11816694_+ncRNA_intronic
CAediting_1253392chr18_11817772_+ncRNA_intronic
CAediting_1253393chr18_11832596_+ncRNA_intronic
CAediting_1253394chr18_11832766_+ncRNA_intronic
CAediting_1253395chr18_11833144_+ncRNA_intronic
CAediting_1253396chr18_11833197_+ncRNA_intronic
CAediting_1253397chr18_11833198_+ncRNA_intronic
CAediting_1253398chr18_11833212_+ncRNA_intronic
CAediting_1253399chr18_11833222_+ncRNA_intronic
CAediting_1253400chr18_11834597_+intronic
CAediting_1253401chr18_11837040_+intronic
CAediting_1253402chr18_11839288_+intronic
CAediting_1253403chr18_11839405_+intronic
CAediting_1253404chr18_11839479_+intronic
CAediting_1253405chr18_11839497_+intronic
CAediting_1253406chr18_11840906_+intronic
CAediting_1253407chr18_11840967_+intronic
CAediting_1253408chr18_11840985_+intronic
CAediting_1253409chr18_11841007_+intronic
CAediting_1253410chr18_11841038_+intronic
CAediting_1253411chr18_11841048_+intronic
CAediting_1253412chr18_11841388_+intronic
CAediting_1253413chr18_11841391_+intronic
CAediting_1253414chr18_11841426_+intronic
CAediting_1253415chr18_11841436_+intronic
CAediting_1253416chr18_11841445_+intronic
CAediting_1253417chr18_11841470_+intronic
CAediting_1253418chr18_11841524_+intronic
CAediting_1253419chr18_11841546_+intronic
CAediting_1253420chr18_11841547_+intronic
CAediting_1253421chr18_11841551_+intronic
CAediting_1253422chr18_11841565_+intronic
CAediting_1253423chr18_11841566_+intronic
CAediting_1253424chr18_11841632_+intronic
CAediting_1253425chr18_11843405_+intronic
CAediting_1253426chr18_11848582_+intronic
CAediting_1253427chr18_11848583_+intronic
CAediting_1253428chr18_11848725_+intronic
CAediting_1253429chr18_11849295_+intronic
CAediting_1253430chr18_11849331_+intronic
CAediting_1253431chr18_11849457_+intronic
CAediting_1253432chr18_11849459_+intronic
CAediting_1253433chr18_11849530_+intronic
CAediting_1253434chr18_11853175_+UTR3
CAediting_1253435chr18_11853176_+UTR3
CAediting_1253436chr18_11853940_+ncRNA_exonic
CAediting_1253437chr18_11853952_+ncRNA_exonic
CAediting_1253438chr18_11853962_+ncRNA_exonic
CAediting_1253439chr18_11853975_+ncRNA_intronic
CAediting_1253440chr18_11854944_+intronic
CAediting_1253441chr18_11854985_+intronic
CAediting_1253442chr18_11856811_+intronic
CAediting_1253443chr18_11878330_+intronic
CAediting_1253444chr18_11878639_+intronic
CAediting_1253445chr18_11878699_+intronic
CAediting_1253446chr18_11878709_+intronic
CAediting_1253447chr18_11878715_+intronic
CAediting_1253448chr18_11878790_+intronic
CAediting_1253449chr18_11878803_+intronic
CAediting_1253450chr18_11882424_+UTR3
CAediting_1253451chr18_11882432_+UTR3
CAediting_1253452chr18_11882433_+UTR3
CAediting_1253453chr18_11882438_+UTR3
CAediting_1253454chr18_11882468_+UTR3
CAediting_1253455chr18_11882484_+UTR3
CAediting_1253456chr18_11882485_+UTR3
CAediting_1253457chr18_11882487_+UTR3
CAediting_1253458chr18_11882500_+UTR3
CAediting_1253459chr18_11882528_+UTR3
CAediting_1253460chr18_11882530_+UTR3
CAediting_1253461chr18_11882533_+UTR3
CAediting_1253462chr18_11882536_+UTR3
CAediting_1253463chr18_11882539_+UTR3
CAediting_1253464chr18_11882543_+UTR3
CAediting_1253465chr18_11882559_+UTR3
CAediting_1253466chr18_11882575_+UTR3
CAediting_1253467chr18_11882588_+UTR3
CAediting_1253468chr18_11882592_+UTR3
CAediting_1253469chr18_11882598_+UTR3
CAediting_1253470chr18_11882607_+UTR3
CAediting_1253471chr18_11882614_+UTR3

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1253361chr18_11763557_+SINEAluAluSx1
CAediting_1253362chr18_11763560_+SINEAluAluSx1
CAediting_1253363chr18_11764345_+SINEAluAluSx1
CAediting_1253364chr18_11764618_+SINEAluAluJb
CAediting_1253365chr18_11771050_+SINEAluAluSq
CAediting_1253366chr18_11771973_+SINEAluAluSx
CAediting_1253368chr18_11795199_+SINEAluAluJb
CAediting_1253369chr18_11795254_+SINEAluAluJb
CAediting_1253370chr18_11795267_+SINEAluAluJb
CAediting_1253371chr18_11795280_+SINEAluAluJb
CAediting_1253372chr18_11795290_+SINEAluAluJb
CAediting_1253373chr18_11795370_+SINEAluAluJb
CAediting_1253374chr18_11796306_+SINEAluAluY
CAediting_1253375chr18_11796322_+SINEAluAluY
CAediting_1253376chr18_11796323_+SINEAluAluY
CAediting_1253377chr18_11796328_+SINEAluAluY
CAediting_1253378chr18_11796345_+SINEAluAluY
CAediting_1253379chr18_11796358_+SINEAluAluY
CAediting_1253380chr18_11796361_+SINEAluAluY
CAediting_1253381chr18_11796377_+SINEAluAluY
CAediting_1253382chr18_11796380_+SINEAluAluY
CAediting_1253383chr18_11796389_+SINEAluAluY
CAediting_1253384chr18_11796390_+SINEAluAluY
CAediting_1253385chr18_11796400_+SINEAluAluY
CAediting_1253386chr18_11796411_+SINEAluAluY
CAediting_1253387chr18_11797116_+SINEAluAluSx
CAediting_1253388chr18_11797117_+SINEAluAluSx
CAediting_1253389chr18_11797480_+SINEAluAluJb
CAediting_1253390chr18_11810211_+SINEAluAluJo
CAediting_1253391chr18_11816694_+SINEAluAluSx1
CAediting_1253392chr18_11817772_+SINEAluAluSx
CAediting_1253393chr18_11832596_+SINEAluAluSq2
CAediting_1253394chr18_11832766_+SINEAluAluSq2
CAediting_1253395chr18_11833144_+SINEAluAluSx1
CAediting_1253396chr18_11833197_+SINEAluAluSx1
CAediting_1253397chr18_11833198_+SINEAluAluSx1
CAediting_1253398chr18_11833212_+SINEAluAluSx1
CAediting_1253399chr18_11833222_+SINEAluAluSx1
CAediting_1253400chr18_11834597_+SINEAluAluJo
CAediting_1253401chr18_11837040_+SINEAluAluSx3
CAediting_1253402chr18_11839288_+SINEAluAluJo
CAediting_1253403chr18_11839405_+SINEAluAluJo
CAediting_1253404chr18_11839479_+SINEAluAluJo
CAediting_1253405chr18_11839497_+SINEAluAluJo
CAediting_1253406chr18_11840906_+SINEAluAluJb
CAediting_1253407chr18_11840967_+SINEAluAluJb
CAediting_1253408chr18_11840985_+SINEAluAluJb
CAediting_1253409chr18_11841007_+SINEAluAluJb
CAediting_1253410chr18_11841038_+SINEAluAluJb
CAediting_1253411chr18_11841048_+SINEAluAluJb
CAediting_1253412chr18_11841388_+SINEAluAluSx
CAediting_1253413chr18_11841391_+SINEAluAluSx
CAediting_1253414chr18_11841426_+SINEAluAluSx
CAediting_1253415chr18_11841436_+SINEAluAluSx
CAediting_1253416chr18_11841445_+SINEAluAluSx
CAediting_1253417chr18_11841470_+SINEAluAluSx
CAediting_1253418chr18_11841524_+SINEAluAluSx
CAediting_1253419chr18_11841546_+SINEAluAluSx
CAediting_1253420chr18_11841547_+SINEAluAluSx
CAediting_1253421chr18_11841551_+SINEAluAluSx
CAediting_1253422chr18_11841565_+SINEAluAluSx
CAediting_1253423chr18_11841566_+SINEAluAluSx
CAediting_1253424chr18_11841632_+SINEAluAluSx
CAediting_1253425chr18_11843405_+SINEAluAluSx
CAediting_1253426chr18_11848582_+SINEAluAluSz
CAediting_1253427chr18_11848583_+SINEAluAluSz
CAediting_1253428chr18_11848725_+SINEAluAluSz
CAediting_1253429chr18_11849295_+SINEAluAluSx
CAediting_1253430chr18_11849331_+SINEAluAluSx
CAediting_1253431chr18_11849457_+SINEAluAluSx
CAediting_1253432chr18_11849459_+SINEAluAluSx
CAediting_1253433chr18_11849530_+SINEAluAluSx
CAediting_1253436chr18_11853940_+SINEAluAluSx
CAediting_1253437chr18_11853952_+SINEAluAluSx
CAediting_1253438chr18_11853962_+SINEAluAluSx
CAediting_1253439chr18_11853975_+SINEAluAluSx
CAediting_1253440chr18_11854944_+SINEAluAluSz
CAediting_1253441chr18_11854985_+SINEAluAluSz
CAediting_1253442chr18_11856811_+SINEAluAluSx
CAediting_1253443chr18_11878330_+SINEAluAluJr
CAediting_1253444chr18_11878639_+SINEAluAluJr
CAediting_1253445chr18_11878699_+SINEAluAluJr
CAediting_1253446chr18_11878709_+SINEAluAluJr
CAediting_1253447chr18_11878715_+SINEAluAluJr
CAediting_1253448chr18_11878790_+SINEAluAluJr
CAediting_1253449chr18_11878803_+SINEAluAluJr
CAediting_1253450chr18_11882424_+SINEAluAluSg
CAediting_1253451chr18_11882432_+SINEAluAluSg
CAediting_1253452chr18_11882433_+SINEAluAluSg
CAediting_1253453chr18_11882438_+SINEAluAluSg
CAediting_1253454chr18_11882468_+SINEAluAluSg
CAediting_1253455chr18_11882484_+SINEAluAluSg
CAediting_1253456chr18_11882485_+SINEAluAluSg
CAediting_1253457chr18_11882487_+SINEAluAluSg
CAediting_1253458chr18_11882500_+SINEAluAluSg
CAediting_1253459chr18_11882528_+SINEAluAluSg
CAediting_1253460chr18_11882530_+SINEAluAluSg
CAediting_1253461chr18_11882533_+SINEAluAluSg
CAediting_1253462chr18_11882536_+SINEAluAluSg
CAediting_1253463chr18_11882539_+SINEAluAluSg
CAediting_1253464chr18_11882543_+SINEAluAluSg
CAediting_1253465chr18_11882559_+SINEAluAluSg
CAediting_1253466chr18_11882575_+SINEAluAluSg
CAediting_1253467chr18_11882588_+SINEAluAluSg
CAediting_1253468chr18_11882592_+SINEAluAluSg
CAediting_1253469chr18_11882598_+SINEAluAluSg
CAediting_1253470chr18_11882607_+SINEAluAluSg
CAediting_1253471chr18_11882614_+SINEAluAluSg

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RNA A-to-I editing events in the alternative splicing sites for GNAL

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000141404.14.GNAL.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000141404.14.GNAL.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GNAL

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for GNAL

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for GNAL

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1253470chr18_11882607_+ENSG00000141404.14ENST00000334049hsa-miR-3155a11882604118826107mer-m81188259111882611145.00-19.96
CAediting_1253470chr18_11882607_+ENSG00000141404.14ENST00000334049hsa-miR-3155b11882604118826107mer-m81188259411882611145.00-19.57
CAediting_1253470chr18_11882607_+ENSG00000141404.14ENST00000334049hsa-miR-48411882604118826107mer-m81188258511882611150.00-24.63
CAediting_1253450chr18_11882424_+ENSG00000141404.14ENST00000334049hsa-miR-463411882421118824277mer-m81188240911882428151.00-24.94
CAediting_1253451chr18_11882432_+ENSG00000141404.14ENST00000334049hsa-miR-513a-5p11882426118824327mer-m81188241611882433144.00-16.68
CAediting_1253451chr18_11882432_+ENSG00000141404.14ENST00000334049hsa-miR-513a-5p11882426118824327mer-m81188241611882433144.00-16.68
CAediting_1253451chr18_11882432_+ENSG00000141404.14ENST00000334049hsa-miR-63811882431118824377mer-1a1188241311882437159.00-35.56
CAediting_1253452chr18_11882433_+ENSG00000141404.14ENST00000334049hsa-miR-805211882431118824377mer-1a1188241911882437140.00-24.15
CAediting_1253453chr18_11882438_+ENSG00000141404.14ENST00000334049hsa-miR-371a-3p11882436118824427mer-m81188242111882443145.00-17.36
CAediting_1253456chr18_11882485_+ENSG00000141404.14ENST00000334049hsa-miR-378a-5p11882481118824866mer1188246511882487140.00-28.88
CAediting_1253458chr18_11882500_+ENSG00000141404.14ENST00000334049hsa-miR-314611882496118825027mer-m81188248311882503143.00-19.32
CAediting_1253460chr18_11882530_+ENSG00000141404.14ENST00000334049hsa-miR-3680-3p11882527118825348mer-1a1188251211882534140.00-15.09
CAediting_1253460chr18_11882530_+ENSG00000141404.14ENST00000334049hsa-miR-3680-3p11882527118825348mer-1a1188251211882534140.00-15.09
CAediting_1253461chr18_11882533_+ENSG00000141404.14ENST00000334049hsa-miR-4742-3p11882526118825338mer-1a1188251111882533142.00-11.50
CAediting_1253463chr18_11882539_+ENSG00000141404.14ENST00000334049hsa-miR-3190-5p11882537118825437mer-m81188252511882544143.00-16.24
CAediting_1253463chr18_11882539_+ENSG00000141404.14ENST00000334049hsa-miR-548s11882536118825427mer-m81188252111882543145.00-11.19
CAediting_1253465chr18_11882559_+ENSG00000141404.14ENST00000334049hsa-miR-6789-3p11882554118825607mer-m81188254111882561155.00-23.93
CAediting_1253466chr18_11882575_+ENSG00000141404.14ENST00000334049hsa-miR-64611882570118825767mer-m81188255911882577145.00-15.05
CAediting_1253467chr18_11882588_+ENSG00000141404.14ENST00000334049hsa-miR-191311882586118825927mer-m81188257211882593151.00-22.13
CAediting_1253467chr18_11882588_+ENSG00000141404.14ENST00000334049hsa-miR-6849-3p11882581118825877mer-m81188256711882588142.00-15.83
CAediting_1253471chr18_11882614_+ENSG00000141404.14ENST00000334049hsa-miR-361-3p11882608118826147mer-m81188258911882615161.00-29.38

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1253451chr18_11882432_+ENSG00000141404.14ENST00000334049hsa-miR-10399-5p11882427118824337mer-m81188241311882434144-11.2
CAediting_1253452chr18_11882433_+ENSG00000141404.14ENST00000334049hsa-miR-10399-5p11882427118824337mer-m81188241311882434144-11.2
CAediting_1253471chr18_11882614_+ENSG00000141404.14ENST00000334049hsa-miR-1306-5p11882611118826177mer-m81188259511882618146-23
CAediting_1253468chr18_11882592_+ENSG00000141404.14ENST00000334049hsa-miR-197611882589118825968mer-1a1188257511882596148-20.9
CAediting_1253463chr18_11882539_+ENSG00000141404.14ENST00000334049hsa-miR-3064-5p11882538118825436mer1188252311882544140-17.25
CAediting_1253464chr18_11882543_+ENSG00000141404.14ENST00000334049hsa-miR-3064-5p11882538118825436mer1188252311882544140-17.25
CAediting_1253458chr18_11882500_+ENSG00000141404.14ENST00000334049hsa-miR-4716-5p11882498118825047mer-m81188248411882505140-10.88
CAediting_1253462chr18_11882536_+ENSG00000141404.14ENST00000334049hsa-miR-4735-5p11882533118825397mer-m81188251911882540144-7.25
CAediting_1253463chr18_11882539_+ENSG00000141404.14ENST00000334049hsa-miR-4735-5p11882533118825397mer-m81188251911882540144-7.25
CAediting_1253463chr18_11882539_+ENSG00000141404.14ENST00000334049hsa-miR-479411882537118825437mer-m81188252311882544140-12.3
CAediting_1253464chr18_11882543_+ENSG00000141404.14ENST00000334049hsa-miR-479411882537118825437mer-m81188252311882544140-12.3
CAediting_1253452chr18_11882433_+ENSG00000141404.14ENST00000334049hsa-miR-5089-5p11882431118824377mer-m81188241611882438148-14.13
CAediting_1253453chr18_11882438_+ENSG00000141404.14ENST00000334049hsa-miR-5089-5p11882431118824377mer-m81188241611882438148-14.13
CAediting_1253453chr18_11882438_+ENSG00000141404.14ENST00000334049hsa-miR-512-3p11882436118824427mer-m81188242211882443149-15.51
CAediting_1253453chr18_11882438_+ENSG00000141404.14ENST00000334049hsa-miR-512-3p11882436118824427mer-m81188242211882443149-15.51
CAediting_1253465chr18_11882559_+ENSG00000141404.14ENST00000334049hsa-miR-552-3p11882557118825648mer-1a1188254411882564148-16.8
CAediting_1253451chr18_11882432_+ENSG00000141404.14ENST00000334049hsa-miR-6504-3p11882427118824337mer-m81188241311882434148-14.35
CAediting_1253452chr18_11882433_+ENSG00000141404.14ENST00000334049hsa-miR-6504-3p11882427118824337mer-m81188241311882434148-14.35
CAediting_1253453chr18_11882438_+ENSG00000141404.14ENST00000334049hsa-miR-6506-5p11882432118824387mer-m81188241711882439144-13.78
CAediting_1253463chr18_11882539_+ENSG00000141404.14ENST00000334049hsa-miR-664a-5p11882537118825437mer-m81188252111882544141-15.73
CAediting_1253464chr18_11882543_+ENSG00000141404.14ENST00000334049hsa-miR-664a-5p11882537118825437mer-m81188252111882544141-15.73
CAediting_1253468chr18_11882592_+ENSG00000141404.14ENST00000334049hsa-miR-6747-3p11882587118825948mer-1a1188257211882594153-23.72
CAediting_1253450chr18_11882424_+ENSG00000141404.14ENST00000334049hsa-miR-6807-5p11882417118824237mer-m81188240211882424148-25.15
CAediting_1253451chr18_11882432_+ENSG00000141404.14ENST00000334049hsa-miR-7151-3p11882425118824328mer-1a1188241211882432144-16.51
CAediting_1253465chr18_11882559_+ENSG00000141404.14ENST00000334049hsa-miR-76411882556118825627mer-m81188254211882563149-23.81

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000141404.14ENST00000334049hsa-miR-605-3p11883245118832517mer-1a1188323011883251141-22.86
CAediting_748296chr10_51299626_+ENSG00000141404.14ENST00000334049hsa-miR-605-3p11885457118854637mer-m81188544311885464140-15.01
CAediting_846604chr11_93733708_-ENSG00000141404.14ENST00000334049hsa-miR-1304-3p11884979118849857mer-m81188496611884986146-24.93
CAediting_980496chr14_31014685_-ENSG00000141404.14ENST00000334049hsa-miR-624-3p11882509118825157mer-m81188249611882516156-16.49
CAediting_393chr1_1167164_+ENSG00000141404.14ENST00000334049hsa-miR-200b-3p11883101118831077mer-m81188308711883108147-9.79
CAediting_1229414chr17_67471546_+ENSG00000141404.14ENST00000334049hsa-miR-548aa11883903118839097mer-m81188388611883910140-12.74
CAediting_1229415chr17_67471547_+ENSG00000141404.14ENST00000334049hsa-miR-548aa11885571118855777mer-m81188555311885578166-17.59
CAediting_1306323chr19_13836462_-ENSG00000141404.14ENST00000334049hsa-miR-27a-3p11881490118814967mer-m81188147611881497155-12.79
CAediting_86358chr1_109598906_+ENSG00000141404.14ENST00000334049hsa-miR-197-5p11883930118839367mer-m81188390911883937146-31.3
CAediting_396018chr5_1062918_-ENSG00000141404.14ENST00000334049hsa-miR-463511883920118839267mer-m81188390711883927162-21.35
CAediting_580943chr7_100356700_+ENSG00000141404.14ENST00000334049hsa-miR-6840-3p11883785118837917mer-m81188377611883792141-29.52
CAediting_468389chr6_31355314_-ENSG00000141404.14ENST00000334049hsa-miR-6891-5p11884749118847568mer-1a1188473811884756145-21.27
CAediting_1524209chrX_134546392_-ENSG00000141404.14ENST00000334049hsa-miR-503-5p11881229118812357mer-m81188120611881236154-31.48
CAediting_1524209chrX_134546392_-ENSG00000141404.14ENST00000269162hsa-miR-503-5p11881229118812357mer-m81188120611881236154-31.48

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_442554chr5_154685830_+ENSG00000141404.14ENST00000334049hsa-miR-130311881767118817748mer-1a1188175311881774142-9.45
CAediting_1054808chr15_66496985_-ENSG00000141404.14ENST00000334049hsa-miR-451211884117118841237mer-m81188410311884124140-19.41
CAediting_1054808chr15_66496985_-ENSG00000141404.14ENST00000334049hsa-miR-451211884746118847516mer1188472811884752143-24.79
CAediting_396018chr5_1062918_-ENSG00000141404.14ENST00000334049hsa-miR-463511882300118823067mer-m81188228711882307140-10.78
CAediting_1524209chrX_134546392_-ENSG00000141404.14ENST00000334049hsa-miR-503-5p11881666118816727mer-m81188165111881673141-20.23
CAediting_1524209chrX_134546392_-ENSG00000141404.14ENST00000334049hsa-miR-503-5p11881993118819986mer1188197711881999145-18.89
CAediting_1229413chr17_67471544_+ENSG00000141404.14ENST00000334049hsa-miR-548aa11881467118814737mer-m81188145111881474149-10.66
CAediting_1229414chr17_67471546_+ENSG00000141404.14ENST00000334049hsa-miR-548aa11881467118814737mer-m81188145111881474149-10.66
CAediting_1229415chr17_67471547_+ENSG00000141404.14ENST00000334049hsa-miR-548aa11881467118814737mer-m81188145111881474149-10.66
CAediting_228905chr2_188297554_+ENSG00000141404.14ENST00000334049hsa-miR-561-3p11882345118823517mer-m81188233111882352140-8.67
CAediting_228905chr2_188297554_+ENSG00000141404.14ENST00000334049hsa-miR-561-3p11885660118856667mer-m81188564511885667151-8.52
CAediting_748296chr10_51299626_+ENSG00000141404.14ENST00000334049hsa-miR-605-3p11884709118847157mer-m81188469511884716144-12.1
CAediting_580943chr7_100356700_+ENSG00000141404.14ENST00000334049hsa-miR-6840-3p11884124118841307mer-m81188410611884131142-24.82
CAediting_1399425chr20_1392958_-ENSG00000141404.14ENST00000334049hsa-miR-6869-5p11883378118833847mer-1a1188336311883384143-23.7

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GNAL

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for GNAL

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BLCACAediting_1253384chr18_11796390_+..0.007591377026171550.302042425541977..
LIHCCAediting_1253384chr18_11796390_+0.01735143909993320.236314800957863....
CESCCAediting_1253384chr18_11796390_+1.8761776431185e-050.415716812509416....
LUADCAediting_1253384chr18_11796390_+0.005157307612209530.37538434329684....
LUSCCAediting_1253384chr18_11796390_+0.03595002659278480.280953120703851....

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Relation with cancer stages for GNAL

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
LUSCpathologic_stageCAediting_1253384chr18_11796390_+0.01150487931679330.341463673825794

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Relation with survival for GNAL

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for GNAL

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GNAL

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
GNALC3554447DYSTONIA 255GENOMICS_ENGLAND;ORPHANET;UNIPROT
GNALC0005586Bipolar Disorder1PSYGENET
GNALC0013421Dystonia1CTD_human
GNALC0036341Schizophrenia1PSYGENET
GNALC0393588Dystonia, Paroxysmal1CTD_human
GNALC0393593Dystonia Disorders1CTD_human
GNALC0393598Idiopathic familial dystonia1CTD_human
GNALC0393610Dystonia, Diurnal1CTD_human
GNALC0743332Focal Dystonia1CTD_human
GNALC0751093Dystonia, Limb1CTD_human
GNALC0752197Adult-Onset Dystonias1CTD_human
GNALC0752198Adult-Onset Idiopathic Focal Dystonias1CTD_human
GNALC0752199Adult-Onset Idiopathic Torsion Dystonias1CTD_human
GNALC0752200Autosomal Dominant Familial Dystonia1CTD_human
GNALC0752201Autosomal Recessive Familial Dystonia1CTD_human
GNALC0752202Childhood Onset Dystonias1CTD_human
GNALC0752203Dystonia, Primary1CTD_human
GNALC0752205Dystonia, Secondary1CTD_human
GNALC0752206Dystonias, Sporadic1CTD_human
GNALC0752207Familial Dystonia1CTD_human
GNALC0752208Pseudodystonia1CTD_human
GNALC4316810Writer's Cramp1CTD_human