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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: GLI1 (CAeditome ID:2735) |
Gene summary for GLI1 |
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Gene information | Gene symbol | GLI1 | Gene ID | 2735 |
Gene name | GLI family zinc finger 1 | |
Synonyms | GLI|PAPA8|PPD1 | |
Cytomap | 12q13.3 | |
Type of gene | protein-coding | |
Description | zinc finger protein GLI1GLI-Kruppel family member GLI1glioma-associated oncogene 1glioma-associated oncogene homolog 1 (zinc finger protein)oncogene GLI | |
Modification date | 20210531 | |
UniProtAcc | P08151 | |
Context | - 23324600(RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling) |
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Gene | GO ID | GO term | PubMed ID |
GLI1 | GO:0045944 | Zinc finger protein GLI1 | 10693759 |
GLI1 | GO:0045944 | Zinc finger protein GLI1 | 9118802 |
GLI1 | GO:0000976 | Zinc finger protein GLI1 | 17035233 |
GLI1 | GO:0000977 | Zinc finger protein GLI1 | 18298960 |
GLI1 | GO:0003677 | Zinc finger protein GLI1 | 9118802 |
GLI1 | GO:0001649 | Zinc finger protein GLI1 | 12165851 |
GLI1 | GO:0007224 | Zinc finger protein GLI1 | 19878745 |
GLI1 | GO:0007224 | Zinc finger protein GLI1 | 31279575 |
GLI1 | GO:0009913 | Zinc finger protein GLI1 | 12165851 |
GLI1 | GO:0045740 | Zinc finger protein GLI1 | 12165851 |
GLI1 | GO:0045880 | Zinc finger protein GLI1 | 17035233 |
GLI1 | GO:0045893 | Zinc finger protein GLI1 | 11238441 |
GLI1 | GO:0045893 | Zinc finger protein GLI1 | 12165851 |
GLI1 | GO:0045893 | Zinc finger protein GLI1 | 17035233 |
GLI1 | GO:0045944 | Zinc finger protein GLI1 | 12165851 |
GLI1 | GO:0060045 | Zinc finger protein GLI1 | 28583401 |
GLI1 | GO:1902808 | Zinc finger protein GLI1 | 28583401 |
GLI1 | GO:0005634 | Zinc finger protein GLI1 | 10806483 |
GLI1 | GO:0005634 | Zinc finger protein GLI1 | 11238441 |
GLI1 | GO:0005634 | Zinc finger protein GLI1 | 19878745 |
GLI1 | GO:0005654 | Zinc finger protein GLI1 | 0000052 |
GLI1 | GO:0005737 | Zinc finger protein GLI1 | 10504446 |
GLI1 | GO:0005737 | Zinc finger protein GLI1 | 11238441 |
GLI1 | GO:0005737 | Zinc finger protein GLI1 | 16229683 |
GLI1 | GO:0005737 | Zinc finger protein GLI1 | 19878745 |
GLI1 | GO:0005829 | Zinc finger protein GLI1 | 0000052 |
GLI1 | GO:0005829 | Zinc finger protein GLI1 | 18559511 |
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RNA A-to-I events for GLI1 |
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CAediting_900895(57464284, +), CAediting_900896(57464375, +), CAediting_900897(57464455, +), CAediting_900898(57470843, +), CAediting_900899(57470864, +), |
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RNA editing positional annotations for GLI1 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_900895 | chr12_57464284_+ | ncRNA_intronic |
CAediting_900896 | chr12_57464375_+ | ncRNA_intronic |
CAediting_900897 | chr12_57464455_+ | ncRNA_intronic |
CAediting_900898 | chr12_57470843_+ | exonic |
CAediting_900899 | chr12_57470864_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_900895 | chr12_57464284_+ | SINE | Alu | AluSz |
CAediting_900896 | chr12_57464375_+ | SINE | Alu | AluSz |
CAediting_900897 | chr12_57464455_+ | SINE | Alu | AluSz |
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RNA A-to-I editing events in the alternative splicing sites for GLI1 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GLI1 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for GLI1 |
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The effects of the RNA editing to the miRNA binding sites for GLI1 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for GLI1 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for GLI1 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for GLI1 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for GLI1 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for GLI1 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GLI1 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
GLI1 | C0005684 | Malignant neoplasm of urinary bladder | 1 | CTD_human |
GLI1 | C0005695 | Bladder Neoplasm | 1 | CTD_human |
GLI1 | C0013903 | Ellis-Van Creveld Syndrome | 1 | ORPHANET |
GLI1 | C0023487 | Acute Promyelocytic Leukemia | 1 | CTD_human |
GLI1 | C0079744 | Diffuse Large B-Cell Lymphoma | 1 | CTD_human |
GLI1 | C0238198 | Gastrointestinal Stromal Tumors | 1 | CTD_human |
GLI1 | C1395852 | Polydactyly preaxial type 1 | 1 | GENOMICS_ENGLAND;ORPHANET;UNIPROT |
GLI1 | C2239176 | Liver carcinoma | 1 | CTD_human |
GLI1 | C3179349 | Gastrointestinal Stromal Sarcoma | 1 | CTD_human |
GLI1 | C4721453 | Peripheral Nervous System Diseases | 1 | CTD_human |
GLI1 | C4748277 | POLYDACTYLY, POSTAXIAL, TYPE A8 | 1 | GENOMICS_ENGLAND |