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Editing gene: GCLC (CAeditome ID:2729)

Gene summary for GCLC

Gene summary

Gene information	Gene symbol	GCLC
	Gene ID	2729
	Gene name	glutamate-cysteine ligase catalytic subunit
	Synonyms	GCL\|GCS\|GLCL\|GLCLC
	Cytomap	6p12.1
	Type of gene	protein-coding
	Description	glutamate--cysteine ligase catalytic subunitGCS heavy chaingamma-ECSgamma-glutamylcysteine synthetase
	Modification date	20210518
	UniProtAcc	P48506
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
GCLC	GO:0000287	Glutamate--cysteine ligase catalytic subunit	24639
GCLC	GO:0004357	Glutamate--cysteine ligase catalytic subunit	11972604
GCLC	GO:0004357	Glutamate--cysteine ligase catalytic subunit	8104187
GCLC	GO:0004357	Glutamate--cysteine ligase catalytic subunit	9675072
GCLC	GO:0016595	Glutamate--cysteine ligase catalytic subunit	9841880
GCLC	GO:0043531	Glutamate--cysteine ligase catalytic subunit	24639
GCLC	GO:0006534	Glutamate--cysteine ligase catalytic subunit	2294991
GCLC	GO:0006536	Glutamate--cysteine ligase catalytic subunit	12663448
GCLC	GO:0006536	Glutamate--cysteine ligase catalytic subunit	2294991
GCLC	GO:0006536	Glutamate--cysteine ligase catalytic subunit	9841880
GCLC	GO:0006750	Glutamate--cysteine ligase catalytic subunit	10395918
GCLC	GO:0006750	Glutamate--cysteine ligase catalytic subunit	8104187
GCLC	GO:0006750	Glutamate--cysteine ligase catalytic subunit	9675072
GCLC	GO:0006979	Glutamate--cysteine ligase catalytic subunit	10395918
GCLC	GO:0006979	Glutamate--cysteine ligase catalytic subunit	11972604
GCLC	GO:0009408	Glutamate--cysteine ligase catalytic subunit	8104187
GCLC	GO:0009725	Glutamate--cysteine ligase catalytic subunit	8104187
GCLC	GO:0043066	Glutamate--cysteine ligase catalytic subunit	10439045
GCLC	GO:0045454	Glutamate--cysteine ligase catalytic subunit	10439045
GCLC	GO:0045892	Glutamate--cysteine ligase catalytic subunit	10439045
GCLC	GO:0017109	Glutamate--cysteine ligase catalytic subunit	9675072
GCLC	GO:0017109	Glutamate--cysteine ligase catalytic subunit	9841880

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RNA A-to-I events for GCLC

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000001084.9

RNA A-to-I editing events in Cancer.

CAediting_487281(53501055, -), CAediting_487282(53517155, -), CAediting_487283(53517356, -), CAediting_487284(53521240, -), CAediting_487285(53521263, -), CAediting_487286(53521331, -), CAediting_487287(53521334, -), CAediting_487288(53521337, -), CAediting_487289(53521729, -), CAediting_487290(53521739, -), CAediting_487291(53521807, -), CAediting_487292(53533860, -), CAediting_487293(53533862, -), CAediting_487294(53533880, -), CAediting_487295(53533891, -), CAediting_487296(53533897, -), CAediting_487297(53533900, -), CAediting_487298(53533903, -), CAediting_487299(53533906, -), CAediting_487300(53533920, -), CAediting_487301(53533932, -), CAediting_487302(53533933, -), CAediting_487303(53533943, -), CAediting_487304(53533959, -), CAediting_487305(53533988, -), CAediting_487306(53533989, -), CAediting_487307(53534013, -), CAediting_487308(53534032, -), CAediting_487309(53534067, -), CAediting_487310(53534068, -), CAediting_487311(53535402, -), CAediting_487312(53535406, -), CAediting_487313(53535427, -), CAediting_487314(53535431, -), CAediting_487315(53537534, -), CAediting_487316(53537579, -), CAediting_487317(53538465, -), CAediting_487318(53538536, -), CAediting_487319(53538552, -), CAediting_487320(53541049, -), CAediting_487321(53541052, -), CAediting_487322(53541067, -), CAediting_487323(53541100, -), CAediting_487324(53541133, -), CAediting_487325(53541134, -), CAediting_487326(53541944, -), CAediting_487327(53541957, -), CAediting_487328(53541965, -), CAediting_487329(53541976, -), CAediting_487330(53542000, -), CAediting_487331(53542045, -), CAediting_487332(53542052, -), CAediting_487333(53542056, -), CAediting_487334(53542075, -), CAediting_487335(53542076, -), CAediting_487336(53542113, -), CAediting_487337(53542121, -), CAediting_487338(53542123, -), CAediting_487339(53542124, -), CAediting_487340(53542130, -), CAediting_487341(53542829, -), CAediting_487342(53549097, -), CAediting_487343(53549107, -), CAediting_487344(53549116, -), CAediting_487345(53549127, -), CAediting_487346(53549135, -), CAediting_487347(53550134, -), CAediting_487348(53550171, -), CAediting_487349(53550172, -), CAediting_487350(53550215, -), CAediting_487351(53550268, -), CAediting_487352(53550277, -), CAediting_487353(53550320, -), CAediting_487354(53550339, -), CAediting_487355(53550344, -), CAediting_487356(53550352, -), CAediting_487357(53550353, -), CAediting_487358(53550369, -), CAediting_487359(53550374, -), CAediting_487360(53550381, -), CAediting_487361(53550393, -), CAediting_487362(53550427, -), CAediting_487363(53550432, -), CAediting_487364(53550435, -), CAediting_487365(53550466, -), CAediting_487366(53550471, -), CAediting_487367(53550511, -), CAediting_487368(53550857, -), CAediting_487369(53550869, -), CAediting_487370(53550870, -), CAediting_487371(53550902, -), CAediting_487372(53550952, -), CAediting_487373(53550957, -), CAediting_487374(53550992, -), CAediting_487375(53551002, -), CAediting_487376(53551006, -), CAediting_487377(53551014, -), CAediting_487378(53551019, -), CAediting_487379(53551031, -), CAediting_487380(53551079, -), CAediting_487381(53551091, -), CAediting_487382(53551099, -), CAediting_487383(53559315, -), CAediting_487384(53559324, -), CAediting_487385(53559336, -), CAediting_487386(53559337, -), CAediting_487387(53559355, -), CAediting_487388(53559359, -), CAediting_487389(53559389, -), CAediting_487390(53559398, -), CAediting_487391(53559408, -), CAediting_487392(53559415, -), CAediting_487393(53559418, -), CAediting_487394(53559436, -), CAediting_487395(53559444, -), CAediting_487396(53559456, -), CAediting_487397(53559460, -), CAediting_487398(53559462, -), CAediting_487399(53559465, -), CAediting_487400(53559484, -), CAediting_487401(53559498, -), CAediting_487402(53559499, -), CAediting_487403(53559503, -), CAediting_487404(53559511, -), CAediting_487405(53559516, -), CAediting_487406(53559522, -), CAediting_487407(53559528, -), CAediting_487408(53559538, -), CAediting_487409(53559539, -), CAediting_487410(53559563, -), CAediting_487411(53559571, -), CAediting_487412(53559579, -), CAediting_487413(53559583, -), CAediting_487414(53559779, -), CAediting_487415(53559782, -), CAediting_487416(53559783, -), CAediting_487417(53559788, -), CAediting_487418(53559794, -), CAediting_487419(53559817, -), CAediting_487420(53559825, -), CAediting_487421(53559842, -), CAediting_487422(53559849, -), CAediting_487423(53559850, -), CAediting_487424(53559851, -), CAediting_487425(53559858, -), CAediting_487426(53559864, -), CAediting_487427(53559868, -), CAediting_487428(53559881, -), CAediting_487429(53559885, -), CAediting_487430(53559890, -), CAediting_487431(53559913, -), CAediting_487432(53559917, -), CAediting_487433(53559930, -), CAediting_487434(53559931, -), CAediting_487435(53559932, -), CAediting_487436(53559957, -), CAediting_487437(53559971, -), CAediting_487438(53559980, -), CAediting_487439(53559993, -), CAediting_487440(53560018, -), CAediting_487441(53560024, -), CAediting_487442(53560046, -), CAediting_487443(53566417, -), CAediting_487444(53566456, -), CAediting_487445(53568448, -), CAediting_487446(53568489, -), CAediting_487447(53575849, -), CAediting_487448(53575850, -), CAediting_487449(53575855, -), CAediting_487450(53575890, -), CAediting_487451(53575891, -), CAediting_487452(53575957, -), CAediting_487453(53576024, -), CAediting_487454(53576030, -), CAediting_487455(53576031, -), CAediting_487456(53577266, -), CAediting_487457(53577278, -), CAediting_487458(53577305, -), CAediting_487459(53577306, -), CAediting_487460(53577343, -), CAediting_487461(53577439, -), CAediting_487462(53577473, -), CAediting_487463(53577767, -), CAediting_487464(53577803, -), CAediting_487465(53577842, -), CAediting_487466(53577843, -), CAediting_487467(53577919, -), CAediting_487468(53579086, -), CAediting_487469(53579100, -), CAediting_487470(53579126, -), CAediting_487471(53579127, -), CAediting_487472(53579162, -), CAediting_487473(53579171, -), CAediting_487474(53579177, -), CAediting_487475(53579207, -), CAediting_487476(53579208, -), CAediting_487477(53579256, -), CAediting_487478(53579262, -), CAediting_487479(53579472, -), CAediting_487480(53580738, -), CAediting_487481(53583401, -), CAediting_487482(53586957, -), CAediting_487483(53599973, -), CAediting_487484(53599988, -), CAediting_487485(53600036, -), CAediting_487486(53600058, -), CAediting_487487(53600061, -), CAediting_487488(53600062, -), CAediting_487489(53600084, -), CAediting_487490(53601359, -), CAediting_487491(53601380, -), CAediting_487492(53601385, -), CAediting_487493(53601549, -), CAediting_487494(53601552, -), CAediting_487495(53603101, -), CAediting_487496(53603128, -), CAediting_487497(53604228, -), CAediting_487498(53604276, -), CAediting_487499(53608081, -), CAediting_487500(53608085, -), CAediting_487501(53608094, -), CAediting_487502(53608102, -), CAediting_487503(53608108, -), CAediting_487504(53608136, -), CAediting_487505(53608140, -), CAediting_487506(53608142, -), CAediting_487507(53608151, -), CAediting_487508(53608154, -), CAediting_487509(53608166, -), CAediting_487510(53608188, -), CAediting_487511(53608189, -), CAediting_487512(53608190, -), CAediting_487513(53608191, -), CAediting_487514(53608199, -), CAediting_487515(53608236, -), CAediting_487516(53608244, -), CAediting_487517(53608245, -), CAediting_487518(53608783, -), CAediting_487519(53608791, -), CAediting_487520(53608824, -), CAediting_487521(53608845, -), CAediting_487522(53608851, -), CAediting_487523(53608859, -), CAediting_487524(53608860, -), CAediting_487525(53608867, -), CAediting_487526(53608885, -), CAediting_487527(53608895, -), CAediting_487528(53608898, -), CAediting_487529(53608907, -), CAediting_487530(53608912, -), CAediting_487531(53608920, -), CAediting_487532(53608924, -), CAediting_487533(53608932, -), CAediting_487534(53609008, -), CAediting_487535(53610097, -), CAediting_487536(53610098, -), CAediting_487537(53610103, -), CAediting_487538(53610158, -), CAediting_487539(53610162, -), CAediting_487540(53610166, -), CAediting_487541(53610172, -), CAediting_487542(53610175, -), CAediting_487543(53613891, -), CAediting_487544(53613896, -), CAediting_487545(53613920, -), CAediting_487546(53613947, -), CAediting_487547(53614870, -), CAediting_487548(53614879, -), CAediting_487549(53614905, -),

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RNA editing positional annotations for GCLC using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_487281	chr6_53501055_-	ncRNA_exonic
CAediting_487282	chr6_53517155_-	intronic
CAediting_487283	chr6_53517356_-	intronic
CAediting_487284	chr6_53521240_-	intronic
CAediting_487285	chr6_53521263_-	intronic
CAediting_487286	chr6_53521331_-	intronic
CAediting_487287	chr6_53521334_-	intronic
CAediting_487288	chr6_53521337_-	intronic
CAediting_487289	chr6_53521729_-	intronic
CAediting_487290	chr6_53521739_-	intronic
CAediting_487291	chr6_53521807_-	intronic
CAediting_487292	chr6_53533860_-	intronic
CAediting_487293	chr6_53533862_-	intronic
CAediting_487294	chr6_53533880_-	intronic
CAediting_487295	chr6_53533891_-	intronic
CAediting_487296	chr6_53533897_-	intronic
CAediting_487297	chr6_53533900_-	intronic
CAediting_487298	chr6_53533903_-	intronic
CAediting_487299	chr6_53533906_-	intronic
CAediting_487300	chr6_53533920_-	intronic
CAediting_487301	chr6_53533932_-	intronic
CAediting_487302	chr6_53533933_-	intronic
CAediting_487303	chr6_53533943_-	intronic
CAediting_487304	chr6_53533959_-	intronic
CAediting_487305	chr6_53533988_-	intronic
CAediting_487306	chr6_53533989_-	intronic
CAediting_487307	chr6_53534013_-	intronic
CAediting_487308	chr6_53534032_-	intronic
CAediting_487309	chr6_53534067_-	intronic
CAediting_487310	chr6_53534068_-	intronic
CAediting_487311	chr6_53535402_-	intronic
CAediting_487312	chr6_53535406_-	intronic
CAediting_487313	chr6_53535427_-	intronic
CAediting_487314	chr6_53535431_-	intronic
CAediting_487315	chr6_53537534_-	intronic
CAediting_487316	chr6_53537579_-	intronic
CAediting_487317	chr6_53538465_-	intronic
CAediting_487318	chr6_53538536_-	intronic
CAediting_487319	chr6_53538552_-	intronic
CAediting_487320	chr6_53541049_-	intronic
CAediting_487321	chr6_53541052_-	intronic
CAediting_487322	chr6_53541067_-	intronic
CAediting_487323	chr6_53541100_-	intronic
CAediting_487324	chr6_53541133_-	intronic
CAediting_487325	chr6_53541134_-	intronic
CAediting_487326	chr6_53541944_-	intronic
CAediting_487327	chr6_53541957_-	intronic
CAediting_487328	chr6_53541965_-	intronic
CAediting_487329	chr6_53541976_-	intronic
CAediting_487330	chr6_53542000_-	intronic
CAediting_487331	chr6_53542045_-	intronic
CAediting_487332	chr6_53542052_-	intronic
CAediting_487333	chr6_53542056_-	intronic
CAediting_487334	chr6_53542075_-	intronic
CAediting_487335	chr6_53542076_-	intronic
CAediting_487336	chr6_53542113_-	intronic
CAediting_487337	chr6_53542121_-	intronic
CAediting_487338	chr6_53542123_-	intronic
CAediting_487339	chr6_53542124_-	intronic
CAediting_487340	chr6_53542130_-	intronic
CAediting_487341	chr6_53542829_-	intronic
CAediting_487342	chr6_53549097_-	intronic
CAediting_487343	chr6_53549107_-	intronic
CAediting_487344	chr6_53549116_-	intronic
CAediting_487345	chr6_53549127_-	intronic
CAediting_487346	chr6_53549135_-	intronic
CAediting_487347	chr6_53550134_-	intronic
CAediting_487348	chr6_53550171_-	intronic
CAediting_487349	chr6_53550172_-	intronic
CAediting_487350	chr6_53550215_-	intronic
CAediting_487351	chr6_53550268_-	intronic
CAediting_487352	chr6_53550277_-	intronic
CAediting_487353	chr6_53550320_-	intronic
CAediting_487354	chr6_53550339_-	intronic
CAediting_487355	chr6_53550344_-	intronic
CAediting_487356	chr6_53550352_-	intronic
CAediting_487357	chr6_53550353_-	intronic
CAediting_487358	chr6_53550369_-	intronic
CAediting_487359	chr6_53550374_-	intronic
CAediting_487360	chr6_53550381_-	intronic
CAediting_487361	chr6_53550393_-	intronic
CAediting_487362	chr6_53550427_-	intronic
CAediting_487363	chr6_53550432_-	intronic
CAediting_487364	chr6_53550435_-	intronic
CAediting_487365	chr6_53550466_-	intronic
CAediting_487366	chr6_53550471_-	intronic
CAediting_487367	chr6_53550511_-	intronic
CAediting_487368	chr6_53550857_-	intronic
CAediting_487369	chr6_53550869_-	intronic
CAediting_487370	chr6_53550870_-	intronic
CAediting_487371	chr6_53550902_-	intronic
CAediting_487372	chr6_53550952_-	intronic
CAediting_487373	chr6_53550957_-	intronic
CAediting_487374	chr6_53550992_-	intronic
CAediting_487375	chr6_53551002_-	intronic
CAediting_487376	chr6_53551006_-	intronic
CAediting_487377	chr6_53551014_-	intronic
CAediting_487378	chr6_53551019_-	intronic
CAediting_487379	chr6_53551031_-	intronic
CAediting_487380	chr6_53551079_-	intronic
CAediting_487381	chr6_53551091_-	intronic
CAediting_487382	chr6_53551099_-	intronic
CAediting_487383	chr6_53559315_-	intronic
CAediting_487384	chr6_53559324_-	intronic
CAediting_487385	chr6_53559336_-	intronic
CAediting_487386	chr6_53559337_-	intronic
CAediting_487387	chr6_53559355_-	intronic
CAediting_487388	chr6_53559359_-	intronic
CAediting_487389	chr6_53559389_-	intronic
CAediting_487390	chr6_53559398_-	intronic
CAediting_487391	chr6_53559408_-	intronic
CAediting_487392	chr6_53559415_-	intronic
CAediting_487393	chr6_53559418_-	intronic
CAediting_487394	chr6_53559436_-	intronic
CAediting_487395	chr6_53559444_-	intronic
CAediting_487396	chr6_53559456_-	intronic
CAediting_487397	chr6_53559460_-	intronic
CAediting_487398	chr6_53559462_-	intronic
CAediting_487399	chr6_53559465_-	intronic
CAediting_487400	chr6_53559484_-	intronic
CAediting_487401	chr6_53559498_-	intronic
CAediting_487402	chr6_53559499_-	intronic
CAediting_487403	chr6_53559503_-	intronic
CAediting_487404	chr6_53559511_-	intronic
CAediting_487405	chr6_53559516_-	intronic
CAediting_487406	chr6_53559522_-	intronic
CAediting_487407	chr6_53559528_-	intronic
CAediting_487408	chr6_53559538_-	intronic
CAediting_487409	chr6_53559539_-	intronic
CAediting_487410	chr6_53559563_-	intronic
CAediting_487411	chr6_53559571_-	intronic
CAediting_487412	chr6_53559579_-	intronic
CAediting_487413	chr6_53559583_-	intronic
CAediting_487414	chr6_53559779_-	intronic
CAediting_487415	chr6_53559782_-	intronic
CAediting_487416	chr6_53559783_-	intronic
CAediting_487417	chr6_53559788_-	intronic
CAediting_487418	chr6_53559794_-	intronic
CAediting_487419	chr6_53559817_-	intronic
CAediting_487420	chr6_53559825_-	intronic
CAediting_487421	chr6_53559842_-	intronic
CAediting_487422	chr6_53559849_-	intronic
CAediting_487423	chr6_53559850_-	intronic
CAediting_487424	chr6_53559851_-	intronic
CAediting_487425	chr6_53559858_-	intronic
CAediting_487426	chr6_53559864_-	intronic
CAediting_487427	chr6_53559868_-	intronic
CAediting_487428	chr6_53559881_-	intronic
CAediting_487429	chr6_53559885_-	intronic
CAediting_487430	chr6_53559890_-	intronic
CAediting_487431	chr6_53559913_-	intronic
CAediting_487432	chr6_53559917_-	intronic
CAediting_487433	chr6_53559930_-	intronic
CAediting_487434	chr6_53559931_-	intronic
CAediting_487435	chr6_53559932_-	intronic
CAediting_487436	chr6_53559957_-	intronic
CAediting_487437	chr6_53559971_-	intronic
CAediting_487438	chr6_53559980_-	intronic
CAediting_487439	chr6_53559993_-	intronic
CAediting_487440	chr6_53560018_-	intronic
CAediting_487441	chr6_53560024_-	intronic
CAediting_487442	chr6_53560046_-	intronic
CAediting_487443	chr6_53566417_-	ncRNA_intronic
CAediting_487444	chr6_53566456_-	ncRNA_intronic
CAediting_487445	chr6_53568448_-	ncRNA_intronic
CAediting_487446	chr6_53568489_-	ncRNA_intronic
CAediting_487447	chr6_53575849_-	ncRNA_intronic
CAediting_487448	chr6_53575850_-	ncRNA_intronic
CAediting_487449	chr6_53575855_-	ncRNA_intronic
CAediting_487450	chr6_53575890_-	ncRNA_intronic
CAediting_487451	chr6_53575891_-	ncRNA_intronic
CAediting_487452	chr6_53575957_-	ncRNA_intronic
CAediting_487453	chr6_53576024_-	ncRNA_intronic
CAediting_487454	chr6_53576030_-	ncRNA_intronic
CAediting_487455	chr6_53576031_-	ncRNA_intronic
CAediting_487456	chr6_53577266_-	ncRNA_intronic
CAediting_487457	chr6_53577278_-	ncRNA_intronic
CAediting_487458	chr6_53577305_-	ncRNA_intronic
CAediting_487459	chr6_53577306_-	ncRNA_intronic
CAediting_487460	chr6_53577343_-	ncRNA_intronic
CAediting_487461	chr6_53577439_-	ncRNA_intronic
CAediting_487462	chr6_53577473_-	ncRNA_intronic
CAediting_487463	chr6_53577767_-	ncRNA_intronic
CAediting_487464	chr6_53577803_-	ncRNA_intronic
CAediting_487465	chr6_53577842_-	ncRNA_intronic
CAediting_487466	chr6_53577843_-	ncRNA_intronic
CAediting_487467	chr6_53577919_-	ncRNA_intronic
CAediting_487468	chr6_53579086_-	ncRNA_intronic
CAediting_487469	chr6_53579100_-	ncRNA_intronic
CAediting_487470	chr6_53579126_-	ncRNA_intronic
CAediting_487471	chr6_53579127_-	ncRNA_intronic
CAediting_487472	chr6_53579162_-	ncRNA_intronic
CAediting_487473	chr6_53579171_-	ncRNA_intronic
CAediting_487474	chr6_53579177_-	ncRNA_intronic
CAediting_487475	chr6_53579207_-	ncRNA_intronic
CAediting_487476	chr6_53579208_-	ncRNA_intronic
CAediting_487477	chr6_53579256_-	ncRNA_intronic
CAediting_487478	chr6_53579262_-	ncRNA_intronic
CAediting_487479	chr6_53579472_-	ncRNA_intronic
CAediting_487480	chr6_53580738_-	ncRNA_intronic
CAediting_487481	chr6_53583401_-	ncRNA_intronic
CAediting_487482	chr6_53586957_-	ncRNA_intronic
CAediting_487483	chr6_53599973_-	ncRNA_intronic
CAediting_487484	chr6_53599988_-	ncRNA_intronic
CAediting_487485	chr6_53600036_-	ncRNA_intronic
CAediting_487486	chr6_53600058_-	ncRNA_intronic
CAediting_487487	chr6_53600061_-	ncRNA_intronic
CAediting_487488	chr6_53600062_-	ncRNA_intronic
CAediting_487489	chr6_53600084_-	ncRNA_intronic
CAediting_487490	chr6_53601359_-	ncRNA_intronic
CAediting_487491	chr6_53601380_-	ncRNA_intronic
CAediting_487492	chr6_53601385_-	ncRNA_intronic
CAediting_487493	chr6_53601549_-	ncRNA_intronic
CAediting_487494	chr6_53601552_-	ncRNA_intronic
CAediting_487495	chr6_53603101_-	ncRNA_intronic
CAediting_487496	chr6_53603128_-	ncRNA_intronic
CAediting_487497	chr6_53604228_-	ncRNA_intronic
CAediting_487498	chr6_53604276_-	ncRNA_intronic
CAediting_487499	chr6_53608081_-	ncRNA_intronic
CAediting_487500	chr6_53608085_-	ncRNA_intronic
CAediting_487501	chr6_53608094_-	ncRNA_intronic
CAediting_487502	chr6_53608102_-	ncRNA_intronic
CAediting_487503	chr6_53608108_-	ncRNA_intronic
CAediting_487504	chr6_53608136_-	ncRNA_intronic
CAediting_487505	chr6_53608140_-	ncRNA_intronic
CAediting_487506	chr6_53608142_-	ncRNA_intronic
CAediting_487507	chr6_53608151_-	ncRNA_intronic
CAediting_487508	chr6_53608154_-	ncRNA_intronic
CAediting_487509	chr6_53608166_-	ncRNA_intronic
CAediting_487510	chr6_53608188_-	ncRNA_intronic
CAediting_487511	chr6_53608189_-	ncRNA_intronic
CAediting_487512	chr6_53608190_-	ncRNA_intronic
CAediting_487513	chr6_53608191_-	ncRNA_intronic
CAediting_487514	chr6_53608199_-	ncRNA_intronic
CAediting_487515	chr6_53608236_-	ncRNA_intronic
CAediting_487516	chr6_53608244_-	ncRNA_intronic
CAediting_487517	chr6_53608245_-	ncRNA_intronic
CAediting_487518	chr6_53608783_-	ncRNA_intronic
CAediting_487519	chr6_53608791_-	ncRNA_intronic
CAediting_487520	chr6_53608824_-	ncRNA_intronic
CAediting_487521	chr6_53608845_-	ncRNA_intronic
CAediting_487522	chr6_53608851_-	ncRNA_intronic
CAediting_487523	chr6_53608859_-	ncRNA_intronic
CAediting_487524	chr6_53608860_-	ncRNA_intronic
CAediting_487525	chr6_53608867_-	ncRNA_intronic
CAediting_487526	chr6_53608885_-	ncRNA_intronic
CAediting_487527	chr6_53608895_-	ncRNA_intronic
CAediting_487528	chr6_53608898_-	ncRNA_intronic
CAediting_487529	chr6_53608907_-	ncRNA_intronic
CAediting_487530	chr6_53608912_-	ncRNA_intronic
CAediting_487531	chr6_53608920_-	ncRNA_intronic
CAediting_487532	chr6_53608924_-	ncRNA_intronic
CAediting_487533	chr6_53608932_-	ncRNA_intronic
CAediting_487534	chr6_53609008_-	ncRNA_intronic
CAediting_487535	chr6_53610097_-	ncRNA_intronic
CAediting_487536	chr6_53610098_-	ncRNA_intronic
CAediting_487537	chr6_53610103_-	ncRNA_intronic
CAediting_487538	chr6_53610158_-	ncRNA_intronic
CAediting_487539	chr6_53610162_-	ncRNA_intronic
CAediting_487540	chr6_53610166_-	ncRNA_intronic
CAediting_487541	chr6_53610172_-	ncRNA_intronic
CAediting_487542	chr6_53610175_-	ncRNA_intronic
CAediting_487543	chr6_53613891_-	ncRNA_intronic
CAediting_487544	chr6_53613896_-	ncRNA_intronic
CAediting_487545	chr6_53613920_-	ncRNA_intronic
CAediting_487546	chr6_53613947_-	ncRNA_intronic
CAediting_487547	chr6_53614870_-	ncRNA_intronic
CAediting_487548	chr6_53614879_-	ncRNA_intronic
CAediting_487549	chr6_53614905_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_487281	chr6_53501055_-	SINE	Alu	AluSz
CAediting_487282	chr6_53517155_-	SINE	Alu	AluJo
CAediting_487283	chr6_53517356_-	SINE	Alu	AluJo
CAediting_487284	chr6_53521240_-	SINE	Alu	AluSz6
CAediting_487285	chr6_53521263_-	SINE	Alu	AluSz6
CAediting_487286	chr6_53521331_-	SINE	Alu	AluSz6
CAediting_487287	chr6_53521334_-	SINE	Alu	AluSz6
CAediting_487288	chr6_53521337_-	SINE	Alu	AluSz6
CAediting_487289	chr6_53521729_-	SINE	Alu	AluY
CAediting_487290	chr6_53521739_-	SINE	Alu	AluY
CAediting_487291	chr6_53521807_-	SINE	Alu	AluY
CAediting_487292	chr6_53533860_-	SINE	Alu	AluSq2
CAediting_487293	chr6_53533862_-	SINE	Alu	AluSq2
CAediting_487294	chr6_53533880_-	SINE	Alu	AluSq2
CAediting_487295	chr6_53533891_-	SINE	Alu	AluSq2
CAediting_487296	chr6_53533897_-	SINE	Alu	AluSq2
CAediting_487297	chr6_53533900_-	SINE	Alu	AluSq2
CAediting_487298	chr6_53533903_-	SINE	Alu	AluSq2
CAediting_487299	chr6_53533906_-	SINE	Alu	AluSq2
CAediting_487300	chr6_53533920_-	SINE	Alu	AluSq2
CAediting_487301	chr6_53533932_-	SINE	Alu	AluSq2
CAediting_487302	chr6_53533933_-	SINE	Alu	AluSq2
CAediting_487303	chr6_53533943_-	SINE	Alu	AluSq2
CAediting_487304	chr6_53533959_-	SINE	Alu	AluSq2
CAediting_487305	chr6_53533988_-	SINE	Alu	AluSq2
CAediting_487306	chr6_53533989_-	SINE	Alu	AluSq2
CAediting_487307	chr6_53534013_-	SINE	Alu	AluSq2
CAediting_487308	chr6_53534032_-	SINE	Alu	AluSq2
CAediting_487309	chr6_53534067_-	SINE	Alu	AluSq2
CAediting_487310	chr6_53534068_-	SINE	Alu	AluSq2
CAediting_487311	chr6_53535402_-	SINE	Alu	AluSx
CAediting_487312	chr6_53535406_-	SINE	Alu	AluSx
CAediting_487313	chr6_53535427_-	SINE	Alu	AluSx
CAediting_487314	chr6_53535431_-	SINE	Alu	AluSx
CAediting_487315	chr6_53537534_-	SINE	Alu	AluJb
CAediting_487316	chr6_53537579_-	SINE	Alu	AluJb
CAediting_487317	chr6_53538465_-	SINE	Alu	AluY
CAediting_487318	chr6_53538536_-	SINE	Alu	AluY
CAediting_487319	chr6_53538552_-	SINE	Alu	AluY
CAediting_487320	chr6_53541049_-	SINE	Alu	AluSq2
CAediting_487321	chr6_53541052_-	SINE	Alu	AluSq2
CAediting_487322	chr6_53541067_-	SINE	Alu	AluSq2
CAediting_487323	chr6_53541100_-	SINE	Alu	AluSq2
CAediting_487324	chr6_53541133_-	SINE	Alu	AluSq2
CAediting_487325	chr6_53541134_-	SINE	Alu	AluSq2
CAediting_487326	chr6_53541944_-	SINE	Alu	AluJo
CAediting_487327	chr6_53541957_-	SINE	Alu	AluJo
CAediting_487328	chr6_53541965_-	SINE	Alu	AluJo
CAediting_487329	chr6_53541976_-	SINE	Alu	AluJo
CAediting_487330	chr6_53542000_-	SINE	Alu	AluJo
CAediting_487331	chr6_53542045_-	SINE	Alu	AluJo
CAediting_487332	chr6_53542052_-	SINE	Alu	AluJo
CAediting_487333	chr6_53542056_-	SINE	Alu	AluJo
CAediting_487334	chr6_53542075_-	SINE	Alu	AluJo
CAediting_487335	chr6_53542076_-	SINE	Alu	AluJo
CAediting_487336	chr6_53542113_-	SINE	Alu	AluJo
CAediting_487337	chr6_53542121_-	SINE	Alu	AluJo
CAediting_487338	chr6_53542123_-	SINE	Alu	AluJo
CAediting_487339	chr6_53542124_-	SINE	Alu	AluJo
CAediting_487340	chr6_53542130_-	SINE	Alu	AluJo
CAediting_487341	chr6_53542829_-	SINE	Alu	AluSx1
CAediting_487342	chr6_53549097_-	SINE	Alu	AluYa5
CAediting_487343	chr6_53549107_-	SINE	Alu	AluYa5
CAediting_487344	chr6_53549116_-	SINE	Alu	AluYa5
CAediting_487345	chr6_53549127_-	SINE	Alu	AluYa5
CAediting_487346	chr6_53549135_-	SINE	Alu	AluYa5
CAediting_487347	chr6_53550134_-	SINE	Alu	AluSx1
CAediting_487348	chr6_53550171_-	SINE	Alu	AluSx1
CAediting_487349	chr6_53550172_-	SINE	Alu	AluSx1
CAediting_487350	chr6_53550215_-	SINE	Alu	AluSx1
CAediting_487351	chr6_53550268_-	SINE	Alu	AluSx1
CAediting_487352	chr6_53550277_-	SINE	Alu	AluSx1
CAediting_487353	chr6_53550320_-	SINE	Alu	AluSx1
CAediting_487354	chr6_53550339_-	SINE	Alu	AluSx1
CAediting_487355	chr6_53550344_-	SINE	Alu	AluSx1
CAediting_487356	chr6_53550352_-	SINE	Alu	AluSx1
CAediting_487357	chr6_53550353_-	SINE	Alu	AluSx1
CAediting_487358	chr6_53550369_-	SINE	Alu	AluSx1
CAediting_487359	chr6_53550374_-	SINE	Alu	AluSx1
CAediting_487360	chr6_53550381_-	SINE	Alu	AluSx1
CAediting_487361	chr6_53550393_-	SINE	Alu	AluSx1
CAediting_487362	chr6_53550427_-	SINE	Alu	AluSx
CAediting_487363	chr6_53550432_-	SINE	Alu	AluSx
CAediting_487364	chr6_53550435_-	SINE	Alu	AluSx
CAediting_487365	chr6_53550466_-	SINE	Alu	AluSx
CAediting_487366	chr6_53550471_-	SINE	Alu	AluSx
CAediting_487367	chr6_53550511_-	SINE	Alu	AluSx
CAediting_487368	chr6_53550857_-	SINE	Alu	AluSx
CAediting_487369	chr6_53550869_-	SINE	Alu	AluSx
CAediting_487370	chr6_53550870_-	SINE	Alu	AluSx
CAediting_487371	chr6_53550902_-	SINE	Alu	AluSx
CAediting_487372	chr6_53550952_-	SINE	Alu	AluSx
CAediting_487373	chr6_53550957_-	SINE	Alu	AluSx
CAediting_487374	chr6_53550992_-	SINE	Alu	AluSx
CAediting_487375	chr6_53551002_-	SINE	Alu	AluSx
CAediting_487376	chr6_53551006_-	SINE	Alu	AluSx
CAediting_487377	chr6_53551014_-	SINE	Alu	AluSx
CAediting_487378	chr6_53551019_-	SINE	Alu	AluSx
CAediting_487379	chr6_53551031_-	SINE	Alu	AluSx
CAediting_487380	chr6_53551079_-	SINE	Alu	AluSx
CAediting_487381	chr6_53551091_-	SINE	Alu	AluSx
CAediting_487382	chr6_53551099_-	SINE	Alu	AluSx
CAediting_487383	chr6_53559315_-	SINE	Alu	AluSx1
CAediting_487384	chr6_53559324_-	SINE	Alu	AluSx1
CAediting_487385	chr6_53559336_-	SINE	Alu	AluSx1
CAediting_487386	chr6_53559337_-	SINE	Alu	AluSx1
CAediting_487387	chr6_53559355_-	SINE	Alu	AluSx1
CAediting_487388	chr6_53559359_-	SINE	Alu	AluSx1
CAediting_487389	chr6_53559389_-	SINE	Alu	AluSx1
CAediting_487390	chr6_53559398_-	SINE	Alu	AluSx1
CAediting_487391	chr6_53559408_-	SINE	Alu	AluSx1
CAediting_487392	chr6_53559415_-	SINE	Alu	AluSx1
CAediting_487393	chr6_53559418_-	SINE	Alu	AluSx1
CAediting_487394	chr6_53559436_-	SINE	Alu	AluSx1
CAediting_487395	chr6_53559444_-	SINE	Alu	AluSx1
CAediting_487396	chr6_53559456_-	SINE	Alu	AluSx1
CAediting_487397	chr6_53559460_-	SINE	Alu	AluSx1
CAediting_487398	chr6_53559462_-	SINE	Alu	AluSx1
CAediting_487399	chr6_53559465_-	SINE	Alu	AluSx1
CAediting_487400	chr6_53559484_-	SINE	Alu	AluSx1
CAediting_487401	chr6_53559498_-	SINE	Alu	AluSx1
CAediting_487402	chr6_53559499_-	SINE	Alu	AluSx1
CAediting_487403	chr6_53559503_-	SINE	Alu	AluSx1
CAediting_487404	chr6_53559511_-	SINE	Alu	AluSx1
CAediting_487405	chr6_53559516_-	SINE	Alu	AluSx1
CAediting_487406	chr6_53559522_-	SINE	Alu	AluSx1
CAediting_487407	chr6_53559528_-	SINE	Alu	AluSx1
CAediting_487408	chr6_53559538_-	SINE	Alu	AluSx1
CAediting_487409	chr6_53559539_-	SINE	Alu	AluSx1
CAediting_487410	chr6_53559563_-	SINE	Alu	AluSx1
CAediting_487411	chr6_53559571_-	SINE	Alu	AluSx1
CAediting_487412	chr6_53559579_-	SINE	Alu	AluSx1
CAediting_487413	chr6_53559583_-	SINE	Alu	AluSx1
CAediting_487414	chr6_53559779_-	SINE	Alu	AluSg
CAediting_487415	chr6_53559782_-	SINE	Alu	AluSg
CAediting_487416	chr6_53559783_-	SINE	Alu	AluSg
CAediting_487417	chr6_53559788_-	SINE	Alu	AluSg
CAediting_487418	chr6_53559794_-	SINE	Alu	AluSg
CAediting_487419	chr6_53559817_-	SINE	Alu	AluSg
CAediting_487420	chr6_53559825_-	SINE	Alu	AluSg
CAediting_487421	chr6_53559842_-	SINE	Alu	AluSg
CAediting_487422	chr6_53559849_-	SINE	Alu	AluSg
CAediting_487423	chr6_53559850_-	SINE	Alu	AluSg
CAediting_487424	chr6_53559851_-	SINE	Alu	AluSg
CAediting_487425	chr6_53559858_-	SINE	Alu	AluSg
CAediting_487426	chr6_53559864_-	SINE	Alu	AluSg
CAediting_487427	chr6_53559868_-	SINE	Alu	AluSg
CAediting_487428	chr6_53559881_-	SINE	Alu	AluSg
CAediting_487429	chr6_53559885_-	SINE	Alu	AluSg
CAediting_487430	chr6_53559890_-	SINE	Alu	AluSg
CAediting_487431	chr6_53559913_-	SINE	Alu	AluSg
CAediting_487432	chr6_53559917_-	SINE	Alu	AluSg
CAediting_487433	chr6_53559930_-	SINE	Alu	AluSg
CAediting_487434	chr6_53559931_-	SINE	Alu	AluSg
CAediting_487435	chr6_53559932_-	SINE	Alu	AluSg
CAediting_487436	chr6_53559957_-	SINE	Alu	AluSg
CAediting_487437	chr6_53559971_-	SINE	Alu	AluSg
CAediting_487438	chr6_53559980_-	SINE	Alu	AluSg
CAediting_487439	chr6_53559993_-	SINE	Alu	AluSg
CAediting_487440	chr6_53560018_-	SINE	Alu	AluSg
CAediting_487441	chr6_53560024_-	SINE	Alu	AluSg
CAediting_487442	chr6_53560046_-	SINE	Alu	AluSg
CAediting_487443	chr6_53566417_-	SINE	Alu	AluSx4
CAediting_487444	chr6_53566456_-	SINE	Alu	AluSx4
CAediting_487445	chr6_53568448_-	SINE	Alu	AluSx1
CAediting_487446	chr6_53568489_-	SINE	Alu	AluSx1
CAediting_487447	chr6_53575849_-	SINE	Alu	AluSz6
CAediting_487448	chr6_53575850_-	SINE	Alu	AluSz6
CAediting_487449	chr6_53575855_-	SINE	Alu	AluSz6
CAediting_487450	chr6_53575890_-	SINE	Alu	AluSz6
CAediting_487451	chr6_53575891_-	SINE	Alu	AluSz6
CAediting_487452	chr6_53575957_-	SINE	Alu	AluSz6
CAediting_487453	chr6_53576024_-	SINE	Alu	AluSz6
CAediting_487454	chr6_53576030_-	SINE	Alu	AluSz6
CAediting_487455	chr6_53576031_-	SINE	Alu	AluSz6
CAediting_487456	chr6_53577266_-	SINE	Alu	AluJb
CAediting_487457	chr6_53577278_-	SINE	Alu	AluJb
CAediting_487458	chr6_53577305_-	SINE	Alu	AluJb
CAediting_487459	chr6_53577306_-	SINE	Alu	AluJb
CAediting_487460	chr6_53577343_-	SINE	Alu	AluJb
CAediting_487461	chr6_53577439_-	SINE	Alu	AluJb
CAediting_487462	chr6_53577473_-	SINE	Alu	AluJb
CAediting_487463	chr6_53577767_-	SINE	Alu	AluJb
CAediting_487464	chr6_53577803_-	SINE	Alu	AluJb
CAediting_487465	chr6_53577842_-	SINE	Alu	AluJb
CAediting_487466	chr6_53577843_-	SINE	Alu	AluJb
CAediting_487467	chr6_53577919_-	SINE	Alu	AluJb
CAediting_487468	chr6_53579086_-	SINE	Alu	AluSz6
CAediting_487469	chr6_53579100_-	SINE	Alu	AluSz6
CAediting_487470	chr6_53579126_-	SINE	Alu	AluSz6
CAediting_487471	chr6_53579127_-	SINE	Alu	AluSz6
CAediting_487472	chr6_53579162_-	SINE	Alu	AluSz6
CAediting_487473	chr6_53579171_-	SINE	Alu	AluSz6
CAediting_487474	chr6_53579177_-	SINE	Alu	AluSz6
CAediting_487475	chr6_53579207_-	SINE	Alu	AluSz6
CAediting_487476	chr6_53579208_-	SINE	Alu	AluSz6
CAediting_487477	chr6_53579256_-	SINE	Alu	AluSz6
CAediting_487478	chr6_53579262_-	SINE	Alu	AluSz6
CAediting_487479	chr6_53579472_-	LTR	ERVL-MaLR	MSTB
CAediting_487480	chr6_53580738_-	SINE	Alu	AluSx1
CAediting_487481	chr6_53583401_-	LTR	ERVL-MaLR	MSTA
CAediting_487482	chr6_53586957_-	SINE	Alu	FLAM_A
CAediting_487483	chr6_53599973_-	SINE	Alu	AluSp
CAediting_487484	chr6_53599988_-	SINE	Alu	AluSp
CAediting_487485	chr6_53600036_-	SINE	Alu	AluSp
CAediting_487486	chr6_53600058_-	SINE	Alu	AluSp
CAediting_487487	chr6_53600061_-	SINE	Alu	AluSp
CAediting_487488	chr6_53600062_-	SINE	Alu	AluSp
CAediting_487489	chr6_53600084_-	SINE	Alu	AluSp
CAediting_487490	chr6_53601359_-	SINE	Alu	AluJb
CAediting_487491	chr6_53601380_-	SINE	Alu	AluJb
CAediting_487492	chr6_53601385_-	SINE	Alu	AluJb
CAediting_487493	chr6_53601549_-	SINE	Alu	AluJb
CAediting_487494	chr6_53601552_-	SINE	Alu	AluJb
CAediting_487495	chr6_53603101_-	SINE	Alu	AluSz6
CAediting_487496	chr6_53603128_-	SINE	Alu	AluSz6
CAediting_487497	chr6_53604228_-	SINE	Alu	AluSg
CAediting_487498	chr6_53604276_-	SINE	Alu	AluSg
CAediting_487499	chr6_53608081_-	SINE	Alu	AluJb
CAediting_487500	chr6_53608085_-	SINE	Alu	AluJb
CAediting_487501	chr6_53608094_-	SINE	Alu	AluJb
CAediting_487502	chr6_53608102_-	SINE	Alu	AluJb
CAediting_487503	chr6_53608108_-	SINE	Alu	AluJb
CAediting_487504	chr6_53608136_-	SINE	Alu	AluJb
CAediting_487505	chr6_53608140_-	SINE	Alu	AluJb
CAediting_487506	chr6_53608142_-	SINE	Alu	AluJb
CAediting_487507	chr6_53608151_-	SINE	Alu	AluJb
CAediting_487508	chr6_53608154_-	SINE	Alu	AluJb
CAediting_487509	chr6_53608166_-	SINE	Alu	AluJb
CAediting_487510	chr6_53608188_-	SINE	Alu	AluJb
CAediting_487511	chr6_53608189_-	SINE	Alu	AluJb
CAediting_487512	chr6_53608190_-	SINE	Alu	AluJb
CAediting_487513	chr6_53608191_-	SINE	Alu	AluJb
CAediting_487514	chr6_53608199_-	SINE	Alu	AluJb
CAediting_487515	chr6_53608236_-	SINE	Alu	AluJb
CAediting_487516	chr6_53608244_-	SINE	Alu	AluJb
CAediting_487517	chr6_53608245_-	SINE	Alu	AluJb
CAediting_487518	chr6_53608783_-	SINE	Alu	AluSz
CAediting_487519	chr6_53608791_-	SINE	Alu	AluSz
CAediting_487520	chr6_53608824_-	SINE	Alu	AluSz
CAediting_487521	chr6_53608845_-	SINE	Alu	AluSz
CAediting_487522	chr6_53608851_-	SINE	Alu	AluSz
CAediting_487523	chr6_53608859_-	SINE	Alu	AluSz
CAediting_487524	chr6_53608860_-	SINE	Alu	AluSz
CAediting_487525	chr6_53608867_-	SINE	Alu	AluSz
CAediting_487526	chr6_53608885_-	SINE	Alu	AluSz
CAediting_487527	chr6_53608895_-	SINE	Alu	AluSz
CAediting_487528	chr6_53608898_-	SINE	Alu	AluSz
CAediting_487529	chr6_53608907_-	SINE	Alu	AluSz
CAediting_487530	chr6_53608912_-	SINE	Alu	AluSz
CAediting_487531	chr6_53608920_-	SINE	Alu	AluSz
CAediting_487532	chr6_53608924_-	SINE	Alu	AluSz
CAediting_487533	chr6_53608932_-	SINE	Alu	AluSz
CAediting_487534	chr6_53609008_-	SINE	Alu	AluSz
CAediting_487535	chr6_53610097_-	SINE	Alu	AluSx
CAediting_487536	chr6_53610098_-	SINE	Alu	AluSx
CAediting_487537	chr6_53610103_-	SINE	Alu	AluSx
CAediting_487538	chr6_53610158_-	SINE	Alu	AluSx
CAediting_487539	chr6_53610162_-	SINE	Alu	AluSx
CAediting_487540	chr6_53610166_-	SINE	Alu	AluSx
CAediting_487541	chr6_53610172_-	SINE	Alu	AluSx
CAediting_487542	chr6_53610175_-	SINE	Alu	AluSx
CAediting_487543	chr6_53613891_-	SINE	Alu	AluJo
CAediting_487544	chr6_53613896_-	SINE	Alu	AluJo
CAediting_487545	chr6_53613920_-	SINE	Alu	AluJo
CAediting_487546	chr6_53613947_-	SINE	Alu	AluJo
CAediting_487547	chr6_53614870_-	SINE	Alu	AluJo
CAediting_487548	chr6_53614879_-	SINE	Alu	AluJo
CAediting_487549	chr6_53614905_-	SINE	Alu	AluJo

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RNA A-to-I editing events in the alternative splicing sites for GCLC

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
ES	CAediting_487291	chr6_53521807_-	53521806:53521828	3SS	2+0i	CTAATTTTTTGTATTTTTAGTAG	5.2	CTAATTTTTTGTATTTTTAGTGG	6.52

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000001084.9.GCLC.

Correlation between RNA A-to-I editing and PSI for ENSG00000001084.9.GCLC.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GCLC

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LIHC.CAediting_487416.ENSG00000001084.GCLC.png
Soverview

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Protein coding region RNA A-to-I editings for GCLC

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for GCLC

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229415	chr17_67471547_+	ENSG00000001084.9	ENST00000514004	hsa-miR-548aa	53513553	53513559	7mer-m8	53513552	53513578	152	-14.91
CAediting_228905	chr2_188297554_+	ENSG00000001084.9	ENST00000514004	hsa-miR-561-3p	53513835	53513841	7mer-m8	53513834	53513858	154	-11.88

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GCLC

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000515580.1	retained_intron

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_487281	ENST00000515580.1	chr6_53501055_-	-597.30	-595.90	-597.30

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Relation with ADAR for GCLC

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LUSC	CAediting_487392	chr6_53559415_-	0.00965090311357114	0.287738969275543	.	.	.	.
LUSC	CAediting_487411	chr6_53559571_-	0.0020824535583649	0.262703925104072	.	.	.	.
LUSC	CAediting_487416	chr6_53559783_-	0.00852213471489743	0.32131451355036	.	.	.	.
LUSC	CAediting_487424	chr6_53559851_-	0.0368729525233726	0.232335066893897	.	.	.	.
LUSC	CAediting_487442	chr6_53560046_-	0.00308934750167785	0.322891468360751	.	.	.	.

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Relation with cancer stages for GCLC

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
LUAD	pathologic_stage	CAediting_487398	chr6_53559462_-	0.0125212841986658	0.331665555496276

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Relation with survival for GCLC

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for GCLC

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
GCLC	P48506	DB00142	Glutamic acid	Glutamate--cysteine ligase catalytic subunit	SmallMoleculeDrug	approved\|nutraceutical
GCLC	P48506	DB00151	Cysteine	Glutamate--cysteine ligase catalytic subunit	SmallMoleculeDrug	approved\|nutraceutical

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RelatedDiseases for GCLC

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
GCLC	C1856603	Gamma-Glutamylcysteine Synthetase Deficiency, Hemolytic Anemia due to	6	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
GCLC	C0036341	Schizophrenia	2	PSYGENET
GCLC	C0268523	Glutamate-cysteine ligase deficiency	2	GENOMICS_ENGLAND
GCLC	C0520572	Enzymopathy	2	GENOMICS_ENGLAND
GCLC	C0002514	Amino Acid Metabolism, Inborn Errors	1	CTD_human
GCLC	C0002878	Anemia, Hemolytic	1	CTD_human
GCLC	C0002879	Anemia, Hemolytic, Acquired	1	CTD_human
GCLC	C0002889	Anemia, Microangiopathic	1	CTD_human
GCLC	C0007131	Non-Small Cell Lung Carcinoma	1	CTD_human
GCLC	C0007621	Neoplastic Cell Transformation	1	CTD_human
GCLC	C0010074	Coronary Vessel Anomalies	1	CTD_human
GCLC	C0011616	Contact Dermatitis	1	CTD_human
GCLC	C0019193	Hepatitis, Toxic	1	CTD_human
GCLC	C0020538	Hypertensive disease	1	CTD_human
GCLC	C0024121	Lung Neoplasms	1	CTD_human
GCLC	C0027051	Myocardial Infarction	1	CTD_human
GCLC	C0151744	Myocardial Ischemia	1	CTD_human
GCLC	C0162351	Contact hypersensitivity	1	CTD_human
GCLC	C0221021	Microangiopathic hemolytic anemia	1	CTD_human
GCLC	C0242379	Malignant neoplasm of lung	1	CTD_human
GCLC	C0750905	Amino Acid Metabolism, Inherited Disorders	1	CTD_human
GCLC	C0860207	Drug-Induced Liver Disease	1	CTD_human
GCLC	C1262760	Hepatitis, Drug-Induced	1	CTD_human
GCLC	C3658290	Drug-Induced Acute Liver Injury	1	CTD_human
GCLC	C4277682	Chemical and Drug Induced Liver Injury	1	CTD_human
GCLC	C4279912	Chemically-Induced Liver Toxicity	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene