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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: SESN1 (CAeditome ID:27244)

Gene summary for SESN1

check button Gene summary
Gene informationGene symbol

SESN1

Gene ID

27244

Gene namesestrin 1
SynonymsPA26|SEST1
Cytomap

6q21

Type of geneprotein-coding
Descriptionsestrin-1p53 activated gene 26p53 regulated PA26 nuclear protein
Modification date20210531
UniProtAcc

Q9Y6P5

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
SESN1

GO:0070728

Sestrin-1

26449471

SESN1

GO:0001650

Sestrin-1

0000052

SESN1

GO:0005634

Sestrin-1

9926927

SESN1

GO:0005654

Sestrin-1

0000052

SESN1

GO:0005737

Sestrin-1

15105503


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RNA A-to-I events for SESN1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000080546.12

check button RNA A-to-I editing events in Cancer.
CAediting_498870(108986574, -), CAediting_498871(108987082, -), CAediting_498872(108987114, -), CAediting_498873(108987961, -), CAediting_498874(108988085, -), CAediting_498875(108988587, -), CAediting_498876(108988589, -), CAediting_498877(108988593, -), CAediting_498878(108988635, -), CAediting_498879(108989568, -), CAediting_498880(108991447, -), CAediting_498881(108992201, -), CAediting_498882(108993838, -), CAediting_498883(108993853, -), CAediting_498884(108994016, -), CAediting_498885(108994114, -), CAediting_498886(108994140, -), CAediting_498887(108994808, -), CAediting_498888(108994954, -), CAediting_498889(108994961, -), CAediting_498890(108994977, -), CAediting_498891(108994999, -), CAediting_498892(108995653, -), CAediting_498893(108995671, -), CAediting_498894(108995673, -), CAediting_498895(108995698, -), CAediting_498896(108995699, -), CAediting_498897(108995738, -), CAediting_498898(108995740, -), CAediting_498899(108995746, -), CAediting_498900(108995748, -), CAediting_498901(108995750, -), CAediting_498902(108995751, -), CAediting_498903(109011705, -), CAediting_498904(109011767, -), CAediting_498905(109011827, -), CAediting_498906(109011828, -), CAediting_498907(109011837, -), CAediting_498908(109011908, -), CAediting_498909(109012850, -), CAediting_498910(109012858, -), CAediting_498911(109012871, -), CAediting_498912(109013030, -), CAediting_498913(109017111, -), CAediting_498914(109017996, -), CAediting_498915(109019532, -), CAediting_498916(109019537, -), CAediting_498917(109021598, -), CAediting_498918(109022498, -), CAediting_498919(109022534, -), CAediting_498920(109022573, -), CAediting_498921(109022579, -), CAediting_498922(109022580, -), CAediting_498923(109022614, -), CAediting_498924(109022651, -), CAediting_498925(109029652, -), CAediting_498926(109035739, -), CAediting_498927(109035807, -), CAediting_498928(109035816, -), CAediting_498929(109040761, -), CAediting_498930(109040768, -), CAediting_498931(109040777, -), CAediting_498932(109041212, -), CAediting_498933(109041226, -), CAediting_498934(109041229, -), CAediting_498935(109041230, -), CAediting_498936(109041300, -), CAediting_498937(109056240, -), CAediting_498938(109058177, -), CAediting_498939(109058181, -), CAediting_498940(109061741, -), CAediting_498941(109062140, -), CAediting_498942(109068781, -), CAediting_498943(109069638, -), CAediting_498944(109069817, -), CAediting_498945(109074070, -), CAediting_498946(109074071, -), CAediting_498947(109074072, -), CAediting_498948(109074118, -), CAediting_498949(109074121, -), CAediting_498950(109074126, -), CAediting_498951(109074143, -), CAediting_498952(109074186, -), CAediting_498953(109074187, -), CAediting_498954(109074188, -), CAediting_498955(109074200, -), CAediting_498956(109074203, -), CAediting_498957(109074211, -), CAediting_498958(109074258, -), CAediting_498959(109074264, -), CAediting_498960(109076935, -), CAediting_498961(109076936, -), CAediting_498962(109076946, -), CAediting_498963(109076953, -), CAediting_498964(109077011, -), CAediting_498965(109077014, -), CAediting_498966(109077016, -), CAediting_498967(109077023, -), CAediting_498968(109077024, -), CAediting_498969(109077051, -), CAediting_498970(109077103, -), CAediting_498971(109077108, -), CAediting_498972(109077118, -), CAediting_498973(109077126, -), CAediting_498974(109077138, -), CAediting_498975(109077143, -), CAediting_498976(109077154, -), CAediting_498977(109077164, -), CAediting_498978(109077174, -), CAediting_498979(109078287, -), CAediting_498980(109081155, -), CAediting_498981(109081193, -), CAediting_498982(109081245, -), CAediting_498983(109081280, -), CAediting_498984(109084470, -), CAediting_498985(109086229, -), CAediting_498986(109087010, -), CAediting_498987(109090861, -), CAediting_498988(109090862, -), CAediting_498989(109090867, -), CAediting_498990(109090886, -), CAediting_498991(109090894, -), CAediting_498992(109090908, -), CAediting_498993(109090934, -), CAediting_498994(109090974, -), CAediting_498995(109091054, -),

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RNA editing positional annotations for SESN1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_498875chr6_108988587_-nonsynonymous SNVENST00000302071.5c.A1150Gp.R384GDBD
CAediting_498875chr6_108988587_-nonsynonymous SNVENST00000356644.7c.A1348Gp.R450GDBD
CAediting_498875chr6_108988587_-nonsynonymous SNVENST00000436639.5c.A1525Gp.R509GDBD
CAediting_498877chr6_108988593_-nonsynonymous SNVENST00000302071.5c.A1144Gp.T382ADBD
CAediting_498877chr6_108988593_-nonsynonymous SNVENST00000356644.7c.A1342Gp.T448ADBD
CAediting_498877chr6_108988593_-nonsynonymous SNVENST00000436639.5c.A1519Gp.T507ADBD
CAediting_498878chr6_108988635_-nonsynonymous SNVENST00000302071.5c.A1102Gp.K368EDDD
CAediting_498878chr6_108988635_-nonsynonymous SNVENST00000356644.7c.A1300Gp.K434EDDD
CAediting_498878chr6_108988635_-nonsynonymous SNVENST00000436639.5c.A1477Gp.K493EDDD

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_498870chr6_108986574_-UTR3
CAediting_498871chr6_108987082_-UTR3
CAediting_498872chr6_108987114_-UTR3
CAediting_498873chr6_108987961_-intronic
CAediting_498874chr6_108988085_-intronic
CAediting_498875chr6_108988587_-exonic
CAediting_498876chr6_108988589_-exonic
CAediting_498877chr6_108988593_-exonic
CAediting_498878chr6_108988635_-exonic
CAediting_498879chr6_108989568_-ncRNA_intronic
CAediting_498880chr6_108991447_-ncRNA_intronic
CAediting_498881chr6_108992201_-ncRNA_intronic
CAediting_498882chr6_108993838_-ncRNA_intronic
CAediting_498883chr6_108993853_-ncRNA_intronic
CAediting_498884chr6_108994016_-ncRNA_intronic
CAediting_498885chr6_108994114_-ncRNA_intronic
CAediting_498886chr6_108994140_-ncRNA_intronic
CAediting_498887chr6_108994808_-ncRNA_intronic
CAediting_498888chr6_108994954_-ncRNA_intronic
CAediting_498889chr6_108994961_-ncRNA_intronic
CAediting_498890chr6_108994977_-ncRNA_intronic
CAediting_498891chr6_108994999_-ncRNA_intronic
CAediting_498892chr6_108995653_-ncRNA_intronic
CAediting_498893chr6_108995671_-ncRNA_intronic
CAediting_498894chr6_108995673_-ncRNA_intronic
CAediting_498895chr6_108995698_-ncRNA_intronic
CAediting_498896chr6_108995699_-ncRNA_intronic
CAediting_498897chr6_108995738_-ncRNA_intronic
CAediting_498898chr6_108995740_-ncRNA_intronic
CAediting_498899chr6_108995746_-ncRNA_intronic
CAediting_498900chr6_108995748_-ncRNA_intronic
CAediting_498901chr6_108995750_-ncRNA_intronic
CAediting_498902chr6_108995751_-ncRNA_intronic
CAediting_498903chr6_109011705_-intronic
CAediting_498904chr6_109011767_-intronic
CAediting_498905chr6_109011827_-intronic
CAediting_498906chr6_109011828_-intronic
CAediting_498907chr6_109011837_-intronic
CAediting_498908chr6_109011908_-intronic
CAediting_498909chr6_109012850_-intronic
CAediting_498910chr6_109012858_-intronic
CAediting_498911chr6_109012871_-intronic
CAediting_498912chr6_109013030_-intronic
CAediting_498913chr6_109017111_-intronic
CAediting_498914chr6_109017996_-intronic
CAediting_498915chr6_109019532_-intronic
CAediting_498916chr6_109019537_-intronic
CAediting_498917chr6_109021598_-intronic
CAediting_498918chr6_109022498_-intronic
CAediting_498919chr6_109022534_-intronic
CAediting_498920chr6_109022573_-intronic
CAediting_498921chr6_109022579_-intronic
CAediting_498922chr6_109022580_-intronic
CAediting_498923chr6_109022614_-intronic
CAediting_498924chr6_109022651_-intronic
CAediting_498925chr6_109029652_-intronic
CAediting_498926chr6_109035739_-intronic
CAediting_498927chr6_109035807_-intronic
CAediting_498928chr6_109035816_-intronic
CAediting_498929chr6_109040761_-intronic
CAediting_498930chr6_109040768_-intronic
CAediting_498931chr6_109040777_-intronic
CAediting_498932chr6_109041212_-intronic
CAediting_498933chr6_109041226_-intronic
CAediting_498934chr6_109041229_-intronic
CAediting_498935chr6_109041230_-intronic
CAediting_498936chr6_109041300_-intronic
CAediting_498937chr6_109056240_-intronic
CAediting_498938chr6_109058177_-intronic
CAediting_498939chr6_109058181_-intronic
CAediting_498940chr6_109061741_-intronic
CAediting_498941chr6_109062140_-intronic
CAediting_498942chr6_109068781_-intronic
CAediting_498943chr6_109069638_-intronic
CAediting_498944chr6_109069817_-intronic
CAediting_498945chr6_109074070_-intronic
CAediting_498946chr6_109074071_-intronic
CAediting_498947chr6_109074072_-intronic
CAediting_498948chr6_109074118_-intronic
CAediting_498949chr6_109074121_-intronic
CAediting_498950chr6_109074126_-intronic
CAediting_498951chr6_109074143_-intronic
CAediting_498952chr6_109074186_-intronic
CAediting_498953chr6_109074187_-intronic
CAediting_498954chr6_109074188_-intronic
CAediting_498955chr6_109074200_-intronic
CAediting_498956chr6_109074203_-intronic
CAediting_498957chr6_109074211_-intronic
CAediting_498958chr6_109074258_-intronic
CAediting_498959chr6_109074264_-intronic
CAediting_498960chr6_109076935_-intronic
CAediting_498961chr6_109076936_-intronic
CAediting_498962chr6_109076946_-intronic
CAediting_498963chr6_109076953_-intronic
CAediting_498964chr6_109077011_-intronic
CAediting_498965chr6_109077014_-intronic
CAediting_498966chr6_109077016_-intronic
CAediting_498967chr6_109077023_-intronic
CAediting_498968chr6_109077024_-intronic
CAediting_498969chr6_109077051_-intronic
CAediting_498970chr6_109077103_-intronic
CAediting_498971chr6_109077108_-intronic
CAediting_498972chr6_109077118_-intronic
CAediting_498973chr6_109077126_-intronic
CAediting_498974chr6_109077138_-intronic
CAediting_498975chr6_109077143_-intronic
CAediting_498976chr6_109077154_-intronic
CAediting_498977chr6_109077164_-intronic
CAediting_498978chr6_109077174_-intronic
CAediting_498979chr6_109078287_-intronic
CAediting_498980chr6_109081155_-intronic
CAediting_498981chr6_109081193_-intronic
CAediting_498982chr6_109081245_-intronic
CAediting_498983chr6_109081280_-intronic
CAediting_498984chr6_109084470_-intronic
CAediting_498985chr6_109086229_-intronic
CAediting_498986chr6_109087010_-intronic
CAediting_498987chr6_109090861_-ncRNA_intronic
CAediting_498988chr6_109090862_-ncRNA_intronic
CAediting_498989chr6_109090867_-ncRNA_intronic
CAediting_498990chr6_109090886_-ncRNA_intronic
CAediting_498991chr6_109090894_-ncRNA_intronic
CAediting_498992chr6_109090908_-ncRNA_intronic
CAediting_498993chr6_109090934_-ncRNA_intronic
CAediting_498994chr6_109090974_-ncRNA_intronic
CAediting_498995chr6_109091054_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_498873chr6_108987961_-SINEAluAluSz
CAediting_498874chr6_108988085_-SINEAluAluSz
CAediting_498880chr6_108991447_-SINEAluAluJr
CAediting_498881chr6_108992201_-SINEAluAluJb
CAediting_498882chr6_108993838_-SINEAluFLAM_A
CAediting_498883chr6_108993853_-SINEAluFLAM_A
CAediting_498884chr6_108994016_-SINEAluAluJr4
CAediting_498885chr6_108994114_-SINEAluAluJr4
CAediting_498886chr6_108994140_-SINEAluAluJr4
CAediting_498887chr6_108994808_-SINEAluAluY
CAediting_498888chr6_108994954_-SINEAluAluY
CAediting_498889chr6_108994961_-SINEAluAluY
CAediting_498890chr6_108994977_-SINEAluAluY
CAediting_498891chr6_108994999_-SINEAluAluY
CAediting_498892chr6_108995653_-SINEAluAluJo
CAediting_498893chr6_108995671_-SINEAluAluJo
CAediting_498894chr6_108995673_-SINEAluAluJo
CAediting_498895chr6_108995698_-SINEAluAluJo
CAediting_498896chr6_108995699_-SINEAluAluJo
CAediting_498897chr6_108995738_-SINEAluAluJo
CAediting_498898chr6_108995740_-SINEAluAluJo
CAediting_498899chr6_108995746_-SINEAluAluJo
CAediting_498900chr6_108995748_-SINEAluAluJo
CAediting_498901chr6_108995750_-SINEAluAluJo
CAediting_498902chr6_108995751_-SINEAluAluJo
CAediting_498903chr6_109011705_-SINEAluAluJr
CAediting_498904chr6_109011767_-SINEAluAluJr
CAediting_498905chr6_109011827_-SINEAluAluJr
CAediting_498906chr6_109011828_-SINEAluAluJr
CAediting_498907chr6_109011837_-SINEAluAluJr
CAediting_498908chr6_109011908_-SINEAluAluJr
CAediting_498909chr6_109012850_-SINEAluAluSc
CAediting_498910chr6_109012858_-SINEAluAluSc
CAediting_498911chr6_109012871_-SINEAluAluSc
CAediting_498912chr6_109013030_-SINEAluAluSc
CAediting_498914chr6_109017996_-SINEAluAluJr
CAediting_498917chr6_109021598_-SINEAluAluSq2
CAediting_498918chr6_109022498_-SINEAluAluY
CAediting_498919chr6_109022534_-SINEAluAluY
CAediting_498920chr6_109022573_-SINEAluAluY
CAediting_498921chr6_109022579_-SINEAluAluY
CAediting_498922chr6_109022580_-SINEAluAluY
CAediting_498923chr6_109022614_-SINEAluAluY
CAediting_498924chr6_109022651_-SINEAluAluY
CAediting_498925chr6_109029652_-SINEAluAluJr
CAediting_498926chr6_109035739_-SINEAluAluJr
CAediting_498927chr6_109035807_-SINEAluAluJr
CAediting_498928chr6_109035816_-SINEAluAluJr
CAediting_498929chr6_109040761_-SINEAluAluSc8
CAediting_498930chr6_109040768_-SINEAluAluSc8
CAediting_498931chr6_109040777_-SINEAluAluSc8
CAediting_498932chr6_109041212_-SINEAluAluJo
CAediting_498933chr6_109041226_-SINEAluAluJo
CAediting_498934chr6_109041229_-SINEAluAluJo
CAediting_498935chr6_109041230_-SINEAluAluJo
CAediting_498936chr6_109041300_-SINEAluAluJo
CAediting_498937chr6_109056240_-SINEAluAluJo
CAediting_498938chr6_109058177_-SINEAluAluJb
CAediting_498939chr6_109058181_-SINEAluAluJb
CAediting_498940chr6_109061741_-SINEAluAluSz
CAediting_498941chr6_109062140_-SINEAluAluJb
CAediting_498942chr6_109068781_-SINEAluAluSq
CAediting_498943chr6_109069638_-SINEAluAluJr4
CAediting_498944chr6_109069817_-SINEAluAluJr4
CAediting_498945chr6_109074070_-DNATcMar-TiggerTigger3a
CAediting_498946chr6_109074071_-DNATcMar-TiggerTigger3a
CAediting_498947chr6_109074072_-DNATcMar-TiggerTigger3a
CAediting_498948chr6_109074118_-DNATcMar-TiggerTigger3a
CAediting_498949chr6_109074121_-DNATcMar-TiggerTigger3a
CAediting_498950chr6_109074126_-DNATcMar-TiggerTigger3a
CAediting_498951chr6_109074143_-DNATcMar-TiggerTigger3a
CAediting_498952chr6_109074186_-DNATcMar-TiggerTigger3a
CAediting_498953chr6_109074187_-DNATcMar-TiggerTigger3a
CAediting_498954chr6_109074188_-DNATcMar-TiggerTigger3a
CAediting_498955chr6_109074200_-DNATcMar-TiggerTigger3a
CAediting_498956chr6_109074203_-DNATcMar-TiggerTigger3a
CAediting_498957chr6_109074211_-DNATcMar-TiggerTigger3a
CAediting_498958chr6_109074258_-DNATcMar-TiggerTigger3a
CAediting_498959chr6_109074264_-DNATcMar-TiggerTigger3a
CAediting_498960chr6_109076935_-DNATcMar-TiggerTigger3a
CAediting_498961chr6_109076936_-DNATcMar-TiggerTigger3a
CAediting_498962chr6_109076946_-DNATcMar-TiggerTigger3a
CAediting_498963chr6_109076953_-DNATcMar-TiggerTigger3a
CAediting_498964chr6_109077011_-DNATcMar-TiggerTigger3a
CAediting_498965chr6_109077014_-DNATcMar-TiggerTigger3a
CAediting_498966chr6_109077016_-DNATcMar-TiggerTigger3a
CAediting_498967chr6_109077023_-DNATcMar-TiggerTigger3a
CAediting_498968chr6_109077024_-DNATcMar-TiggerTigger3a
CAediting_498969chr6_109077051_-DNATcMar-TiggerTigger3a
CAediting_498970chr6_109077103_-DNATcMar-TiggerTigger3a
CAediting_498971chr6_109077108_-DNATcMar-TiggerTigger3a
CAediting_498972chr6_109077118_-DNATcMar-TiggerTigger3a
CAediting_498973chr6_109077126_-DNATcMar-TiggerTigger3a
CAediting_498974chr6_109077138_-DNATcMar-TiggerTigger3a
CAediting_498975chr6_109077143_-DNATcMar-TiggerTigger3a
CAediting_498976chr6_109077154_-DNATcMar-TiggerTigger3a
CAediting_498977chr6_109077164_-DNATcMar-TiggerTigger3a
CAediting_498978chr6_109077174_-DNATcMar-TiggerTigger3a
CAediting_498979chr6_109078287_-SINEAluAluJr
CAediting_498980chr6_109081155_-SINEAluAluJo
CAediting_498981chr6_109081193_-SINEAluAluJo
CAediting_498982chr6_109081245_-SINEAluAluJo
CAediting_498983chr6_109081280_-SINEAluAluJo
CAediting_498984chr6_109084470_-SINEAluAluSq2
CAediting_498985chr6_109086229_-SINEAluAluSz
CAediting_498986chr6_109087010_-SINEAluAluSg
CAediting_498987chr6_109090861_-SINEAluAluJr
CAediting_498988chr6_109090862_-SINEAluAluJr
CAediting_498989chr6_109090867_-SINEAluAluJr
CAediting_498990chr6_109090886_-SINEAluAluJr
CAediting_498991chr6_109090894_-SINEAluAluJr
CAediting_498992chr6_109090908_-SINEAluAluJr
CAediting_498993chr6_109090934_-SINEAluAluJr
CAediting_498994chr6_109090974_-SINEAluAluJr
CAediting_498995chr6_109091054_-SINEAluAluJr

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RNA A-to-I editing events in the alternative splicing sites for SESN1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_498891chr6_108994999_-108994995:1089950173SS0+2iAAGATATAAATTCTGGCCAGGTG3.66AAGATATAAATTCTGGCCGGGTG-4.3

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000080546.12.SESN1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000080546.12.SESN1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SESN1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for SESN1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for SESN1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_498870chr6_108986574_-ENSG00000080546.12ENST00000436639hsa-miR-68441089865731089865797mer-m8108986572108986594147.00-7.17
CAediting_498870chr6_108986574_-ENSG00000080546.12ENST00000302071hsa-miR-68441089865731089865797mer-m8108986572108986594147.00-7.17
CAediting_498870chr6_108986574_-ENSG00000080546.12ENST00000356644hsa-miR-68441089865731089865797mer-m8108986572108986594147.00-7.17
CAediting_498871chr6_108987082_-ENSG00000080546.12ENST00000436639hsa-miR-4482-3p1089870801089870867mer-m8108987079108987099155.00-12.93
CAediting_498871chr6_108987082_-ENSG00000080546.12ENST00000302071hsa-miR-4482-3p1089870801089870867mer-m8108987079108987099155.00-12.93
CAediting_498871chr6_108987082_-ENSG00000080546.12ENST00000356644hsa-miR-4482-3p1089870801089870867mer-m8108987079108987099155.00-12.93

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_498872chr6_108987114_-ENSG00000080546.12ENST00000436639hsa-miR-121231089871141089871207mer-m8108987113108987133152-14.7
CAediting_498872chr6_108987114_-ENSG00000080546.12ENST00000302071hsa-miR-121231089871141089871207mer-m8108987113108987133152-14.7
CAediting_498872chr6_108987114_-ENSG00000080546.12ENST00000356644hsa-miR-121231089871141089871207mer-m8108987113108987133152-14.7

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1160181chr17_7017644_-ENSG00000080546.12ENST00000436639hsa-miR-195-3p1089870701089870767mer-m8108987069108987091155-14.1
CAediting_442554chr5_154685830_+ENSG00000080546.12ENST00000436639hsa-miR-13031089864421089864487mer-m8108986441108986461158-14.86
CAediting_442554chr5_154685830_+ENSG00000080546.12ENST00000436639hsa-miR-13031089872501089872578mer-1a108987250108987272147-14.95
CAediting_1160181chr17_7017644_-ENSG00000080546.12ENST00000302071hsa-miR-195-3p1089870701089870767mer-m8108987069108987091155-14.1
CAediting_442554chr5_154685830_+ENSG00000080546.12ENST00000302071hsa-miR-13031089864421089864487mer-m8108986442108986461158-14.06
CAediting_442554chr5_154685830_+ENSG00000080546.12ENST00000302071hsa-miR-13031089872501089872578mer-1a108987250108987272147-14.95
CAediting_1160181chr17_7017644_-ENSG00000080546.12ENST00000356644hsa-miR-195-3p1089870701089870767mer-m8108987069108987091155-14.1
CAediting_442554chr5_154685830_+ENSG00000080546.12ENST00000356644hsa-miR-13031089864421089864487mer-m8108986442108986461158-14.06
CAediting_442554chr5_154685830_+ENSG00000080546.12ENST00000356644hsa-miR-13031089872501089872578mer-1a108987250108987272147-14.95

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SESN1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000302071.5protein_codingSoverviewSoverview
ENST00000356644.7protein_codingSoverviewSoverview
ENST00000436639.5protein_codingSoverviewSoverview
ENST00000520364.1retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_498870ENST00000302071.5chr6_108986574_--732.30-731.60-740.40
CAediting_498871ENST00000302071.5chr6_108987082_--733.10-731.60-740.40
CAediting_498872ENST00000302071.5chr6_108987114_--732.40-731.60-740.40
CAediting_498875ENST00000302071.5chr6_108988587_--733.50-731.60-740.40
CAediting_498876ENST00000302071.5chr6_108988589_--731.70-731.60-740.40
CAediting_498877ENST00000302071.5chr6_108988593_--731.60-731.60-740.40
CAediting_498878ENST00000302071.5chr6_108988635_--736.10-731.60-740.40
CAediting_498870ENST00000356644.7chr6_108986574_--775.50-774.50-783.60
CAediting_498871ENST00000356644.7chr6_108987082_--776.00-774.50-783.60
CAediting_498872ENST00000356644.7chr6_108987114_--775.30-774.50-783.60
CAediting_498875ENST00000356644.7chr6_108988587_--776.40-774.50-783.60
CAediting_498876ENST00000356644.7chr6_108988589_--774.60-774.50-783.60
CAediting_498877ENST00000356644.7chr6_108988593_--774.80-774.50-783.60
CAediting_498878ENST00000356644.7chr6_108988635_--779.00-774.50-783.60
CAediting_498870ENST00000436639.5chr6_108986574_--1086.30-1085.50-1094.40
CAediting_498871ENST00000436639.5chr6_108987082_--1087.00-1085.50-1094.40
CAediting_498872ENST00000436639.5chr6_108987114_--1086.30-1085.50-1094.40
CAediting_498875ENST00000436639.5chr6_108988587_--1087.40-1085.50-1094.40
CAediting_498876ENST00000436639.5chr6_108988589_--1085.60-1085.50-1094.40
CAediting_498877ENST00000436639.5chr6_108988593_--1085.50-1085.50-1094.40
CAediting_498878ENST00000436639.5chr6_108988635_--1090.00-1085.50-1094.40
CAediting_498875ENST00000520364.1chr6_108988587_--181.10-179.20-185.70
CAediting_498876ENST00000520364.1chr6_108988589_--180.00-179.20-185.70
CAediting_498877ENST00000520364.1chr6_108988593_--180.20-179.20-185.70
CAediting_498878ENST00000520364.1chr6_108988635_--183.70-179.20-185.70

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Relation with ADAR for SESN1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for SESN1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for SESN1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for SESN1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SESN1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource