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Editing gene: OSTF1 (CAeditome ID:26578)

Gene summary for OSTF1

Gene summary

Gene information	Gene symbol	OSTF1
	Gene ID	26578
	Gene name	osteoclast stimulating factor 1
	Synonyms	OSF\|SH3P2\|bA235O14.1
	Cytomap	9q21.13
	Type of gene	protein-coding
	Description	osteoclast-stimulating factor 1
	Modification date	20210518
	UniProtAcc	Q92882
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for OSTF1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000134996.11

RNA A-to-I editing events in Cancer.

CAediting_690286(75090717, +), CAediting_690287(75090718, +), CAediting_690288(75095991, +), CAediting_690289(75096009, +), CAediting_690290(75096018, +), CAediting_690291(75096033, +), CAediting_690292(75096047, +), CAediting_690293(75096057, +), CAediting_690294(75097513, +), CAediting_690295(75097549, +), CAediting_690296(75098532, +), CAediting_690297(75103085, +), CAediting_690298(75103086, +), CAediting_690299(75103101, +), CAediting_690300(75103105, +), CAediting_690301(75103106, +), CAediting_690302(75103692, +), CAediting_690303(75103774, +), CAediting_690304(75103782, +), CAediting_690305(75104123, +), CAediting_690306(75104306, +), CAediting_690307(75104384, +), CAediting_690308(75104396, +), CAediting_690309(75106373, +), CAediting_690310(75106416, +), CAediting_690311(75106444, +), CAediting_690312(75106480, +), CAediting_690313(75106483, +), CAediting_690314(75106484, +), CAediting_690315(75106485, +), CAediting_690316(75106486, +), CAediting_690317(75106489, +), CAediting_690318(75106498, +), CAediting_690319(75106525, +), CAediting_690320(75106534, +), CAediting_690321(75106551, +), CAediting_690322(75106565, +), CAediting_690323(75106566, +), CAediting_690324(75106573, +), CAediting_690325(75106694, +), CAediting_690326(75106789, +), CAediting_690327(75106834, +), CAediting_690328(75106850, +), CAediting_690329(75106856, +), CAediting_690330(75106869, +), CAediting_690331(75106874, +), CAediting_690332(75106875, +), CAediting_690333(75106895, +), CAediting_690334(75109112, +), CAediting_690335(75109196, +), CAediting_690336(75115475, +), CAediting_690337(75141037, +), CAediting_690338(75141043, +), CAediting_690339(75141044, +), CAediting_690340(75141049, +), CAediting_690341(75141065, +), CAediting_690342(75141066, +), CAediting_690343(75141070, +), CAediting_690344(75141079, +), CAediting_690345(75141084, +), CAediting_690346(75141089, +), CAediting_690347(75141098, +), CAediting_690348(75141100, +), CAediting_690349(75141103, +), CAediting_690350(75141109, +), CAediting_690351(75141116, +), CAediting_690352(75141117, +), CAediting_690353(75141135, +), CAediting_690354(75141140, +), CAediting_690355(75141141, +), CAediting_690356(75141149, +), CAediting_690357(75141150, +), CAediting_690358(75141151, +), CAediting_690359(75141154, +), CAediting_690360(75141158, +), CAediting_690361(75141160, +), CAediting_690362(75141180, +), CAediting_690363(75141190, +), CAediting_690364(75141194, +), CAediting_690365(75141197, +), CAediting_690366(75141203, +), CAediting_690367(75141215, +), CAediting_690368(75141220, +), CAediting_690369(75141229, +), CAediting_690370(75141242, +), CAediting_690371(75141246, +), CAediting_690372(75141258, +), CAediting_690373(75141286, +), CAediting_690374(75141287, +), CAediting_690375(75141779, +), CAediting_690376(75141811, +), CAediting_690377(75141887, +), CAediting_690378(75141909, +), CAediting_690379(75141969, +), CAediting_690380(75142000, +), CAediting_690381(75142010, +), CAediting_690382(75143003, +), CAediting_690383(75144294, +), CAediting_690384(75144321, +), CAediting_690385(75144349, +), CAediting_690386(75144369, +), CAediting_690387(75144431, +), CAediting_690388(75144467, +), CAediting_690389(75144477, +),

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RNA editing positional annotations for OSTF1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_690286	chr9_75090717_+	intronic
CAediting_690287	chr9_75090718_+	intronic
CAediting_690288	chr9_75095991_+	intronic
CAediting_690289	chr9_75096009_+	intronic
CAediting_690290	chr9_75096018_+	intronic
CAediting_690291	chr9_75096033_+	intronic
CAediting_690292	chr9_75096047_+	intronic
CAediting_690293	chr9_75096057_+	intronic
CAediting_690294	chr9_75097513_+	intronic
CAediting_690295	chr9_75097549_+	intronic
CAediting_690296	chr9_75098532_+	intronic
CAediting_690297	chr9_75103085_+	intronic
CAediting_690298	chr9_75103086_+	intronic
CAediting_690299	chr9_75103101_+	intronic
CAediting_690300	chr9_75103105_+	intronic
CAediting_690301	chr9_75103106_+	intronic
CAediting_690302	chr9_75103692_+	intronic
CAediting_690303	chr9_75103774_+	intronic
CAediting_690304	chr9_75103782_+	intronic
CAediting_690305	chr9_75104123_+	intronic
CAediting_690306	chr9_75104306_+	intronic
CAediting_690307	chr9_75104384_+	intronic
CAediting_690308	chr9_75104396_+	intronic
CAediting_690309	chr9_75106373_+	intronic
CAediting_690310	chr9_75106416_+	intronic
CAediting_690311	chr9_75106444_+	intronic
CAediting_690312	chr9_75106480_+	intronic
CAediting_690313	chr9_75106483_+	intronic
CAediting_690314	chr9_75106484_+	intronic
CAediting_690315	chr9_75106485_+	intronic
CAediting_690316	chr9_75106486_+	intronic
CAediting_690317	chr9_75106489_+	intronic
CAediting_690318	chr9_75106498_+	intronic
CAediting_690319	chr9_75106525_+	intronic
CAediting_690320	chr9_75106534_+	intronic
CAediting_690321	chr9_75106551_+	intronic
CAediting_690322	chr9_75106565_+	intronic
CAediting_690323	chr9_75106566_+	intronic
CAediting_690324	chr9_75106573_+	intronic
CAediting_690325	chr9_75106694_+	intronic
CAediting_690326	chr9_75106789_+	intronic
CAediting_690327	chr9_75106834_+	intronic
CAediting_690328	chr9_75106850_+	intronic
CAediting_690329	chr9_75106856_+	intronic
CAediting_690330	chr9_75106869_+	intronic
CAediting_690331	chr9_75106874_+	intronic
CAediting_690332	chr9_75106875_+	intronic
CAediting_690333	chr9_75106895_+	intronic
CAediting_690334	chr9_75109112_+	intronic
CAediting_690335	chr9_75109196_+	intronic
CAediting_690336	chr9_75115475_+	intronic
CAediting_690337	chr9_75141037_+	intronic
CAediting_690338	chr9_75141043_+	intronic
CAediting_690339	chr9_75141044_+	intronic
CAediting_690340	chr9_75141049_+	intronic
CAediting_690341	chr9_75141065_+	intronic
CAediting_690342	chr9_75141066_+	intronic
CAediting_690343	chr9_75141070_+	intronic
CAediting_690344	chr9_75141079_+	intronic
CAediting_690345	chr9_75141084_+	intronic
CAediting_690346	chr9_75141089_+	intronic
CAediting_690347	chr9_75141098_+	intronic
CAediting_690348	chr9_75141100_+	intronic
CAediting_690349	chr9_75141103_+	intronic
CAediting_690350	chr9_75141109_+	intronic
CAediting_690351	chr9_75141116_+	intronic
CAediting_690352	chr9_75141117_+	intronic
CAediting_690353	chr9_75141135_+	intronic
CAediting_690354	chr9_75141140_+	intronic
CAediting_690355	chr9_75141141_+	intronic
CAediting_690356	chr9_75141149_+	intronic
CAediting_690357	chr9_75141150_+	intronic
CAediting_690358	chr9_75141151_+	intronic
CAediting_690359	chr9_75141154_+	intronic
CAediting_690360	chr9_75141158_+	intronic
CAediting_690361	chr9_75141160_+	intronic
CAediting_690362	chr9_75141180_+	intronic
CAediting_690363	chr9_75141190_+	intronic
CAediting_690364	chr9_75141194_+	intronic
CAediting_690365	chr9_75141197_+	intronic
CAediting_690366	chr9_75141203_+	intronic
CAediting_690367	chr9_75141215_+	intronic
CAediting_690368	chr9_75141220_+	intronic
CAediting_690369	chr9_75141229_+	intronic
CAediting_690370	chr9_75141242_+	intronic
CAediting_690371	chr9_75141246_+	intronic
CAediting_690372	chr9_75141258_+	intronic
CAediting_690373	chr9_75141286_+	intronic
CAediting_690374	chr9_75141287_+	intronic
CAediting_690375	chr9_75141779_+	intronic
CAediting_690376	chr9_75141811_+	intronic
CAediting_690377	chr9_75141887_+	intronic
CAediting_690378	chr9_75141909_+	intronic
CAediting_690379	chr9_75141969_+	intronic
CAediting_690380	chr9_75142000_+	intronic
CAediting_690381	chr9_75142010_+	intronic
CAediting_690382	chr9_75143003_+	intronic
CAediting_690383	chr9_75144294_+	intronic
CAediting_690384	chr9_75144321_+	intronic
CAediting_690385	chr9_75144349_+	intronic
CAediting_690386	chr9_75144369_+	intronic
CAediting_690387	chr9_75144431_+	intronic
CAediting_690388	chr9_75144467_+	intronic
CAediting_690389	chr9_75144477_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_690286	chr9_75090717_+	SINE	Alu	AluJr
CAediting_690287	chr9_75090718_+	SINE	Alu	AluJr
CAediting_690288	chr9_75095991_+	SINE	Alu	AluY
CAediting_690289	chr9_75096009_+	SINE	Alu	AluY
CAediting_690290	chr9_75096018_+	SINE	Alu	AluY
CAediting_690291	chr9_75096033_+	SINE	Alu	AluY
CAediting_690292	chr9_75096047_+	SINE	Alu	AluY
CAediting_690293	chr9_75096057_+	SINE	Alu	AluY
CAediting_690297	chr9_75103085_+	SINE	Alu	AluJr4
CAediting_690298	chr9_75103086_+	SINE	Alu	AluJr4
CAediting_690299	chr9_75103101_+	SINE	Alu	AluJr4
CAediting_690300	chr9_75103105_+	SINE	Alu	AluJr4
CAediting_690301	chr9_75103106_+	SINE	Alu	AluJr4
CAediting_690302	chr9_75103692_+	SINE	Alu	AluJr
CAediting_690303	chr9_75103774_+	SINE	Alu	AluJr
CAediting_690304	chr9_75103782_+	SINE	Alu	AluJr
CAediting_690305	chr9_75104123_+	SINE	Alu	AluJb
CAediting_690306	chr9_75104306_+	SINE	Alu	AluJr4
CAediting_690307	chr9_75104384_+	SINE	Alu	AluJr4
CAediting_690308	chr9_75104396_+	SINE	Alu	AluJr4
CAediting_690309	chr9_75106373_+	SINE	Alu	AluSq2
CAediting_690310	chr9_75106416_+	SINE	Alu	AluSq2
CAediting_690311	chr9_75106444_+	SINE	Alu	AluSq2
CAediting_690312	chr9_75106480_+	SINE	Alu	AluSq2
CAediting_690313	chr9_75106483_+	SINE	Alu	AluSq2
CAediting_690314	chr9_75106484_+	SINE	Alu	AluSq2
CAediting_690315	chr9_75106485_+	SINE	Alu	AluSq2
CAediting_690316	chr9_75106486_+	SINE	Alu	AluSq2
CAediting_690317	chr9_75106489_+	SINE	Alu	AluSq2
CAediting_690318	chr9_75106498_+	SINE	Alu	AluSq2
CAediting_690319	chr9_75106525_+	SINE	Alu	AluSq2
CAediting_690320	chr9_75106534_+	SINE	Alu	AluSq2
CAediting_690321	chr9_75106551_+	SINE	Alu	AluSq2
CAediting_690322	chr9_75106565_+	SINE	Alu	AluSq2
CAediting_690323	chr9_75106566_+	SINE	Alu	AluSq2
CAediting_690324	chr9_75106573_+	SINE	Alu	AluSq2
CAediting_690325	chr9_75106694_+	SINE	Alu	AluSc
CAediting_690326	chr9_75106789_+	SINE	Alu	AluSc
CAediting_690327	chr9_75106834_+	SINE	Alu	AluSc
CAediting_690328	chr9_75106850_+	SINE	Alu	AluSc
CAediting_690329	chr9_75106856_+	SINE	Alu	AluSc
CAediting_690330	chr9_75106869_+	SINE	Alu	AluSc
CAediting_690331	chr9_75106874_+	SINE	Alu	AluSc
CAediting_690332	chr9_75106875_+	SINE	Alu	AluSc
CAediting_690333	chr9_75106895_+	SINE	Alu	AluSc
CAediting_690334	chr9_75109112_+	SINE	Alu	AluSx1
CAediting_690335	chr9_75109196_+	SINE	Alu	AluSx1
CAediting_690336	chr9_75115475_+	SINE	Alu	AluSz
CAediting_690337	chr9_75141037_+	SINE	Alu	AluJb
CAediting_690338	chr9_75141043_+	SINE	Alu	AluJb
CAediting_690339	chr9_75141044_+	SINE	Alu	AluJb
CAediting_690340	chr9_75141049_+	SINE	Alu	AluJb
CAediting_690341	chr9_75141065_+	SINE	Alu	AluJb
CAediting_690342	chr9_75141066_+	SINE	Alu	AluJb
CAediting_690343	chr9_75141070_+	SINE	Alu	AluJb
CAediting_690344	chr9_75141079_+	SINE	Alu	AluJb
CAediting_690345	chr9_75141084_+	SINE	Alu	AluJb
CAediting_690346	chr9_75141089_+	SINE	Alu	AluJb
CAediting_690347	chr9_75141098_+	SINE	Alu	AluJb
CAediting_690348	chr9_75141100_+	SINE	Alu	AluJb
CAediting_690349	chr9_75141103_+	SINE	Alu	AluJb
CAediting_690350	chr9_75141109_+	SINE	Alu	AluJb
CAediting_690351	chr9_75141116_+	SINE	Alu	AluJb
CAediting_690352	chr9_75141117_+	SINE	Alu	AluJb
CAediting_690353	chr9_75141135_+	SINE	Alu	AluJb
CAediting_690354	chr9_75141140_+	SINE	Alu	AluJb
CAediting_690355	chr9_75141141_+	SINE	Alu	AluJb
CAediting_690356	chr9_75141149_+	SINE	Alu	AluJb
CAediting_690357	chr9_75141150_+	SINE	Alu	AluJb
CAediting_690358	chr9_75141151_+	SINE	Alu	AluJb
CAediting_690359	chr9_75141154_+	SINE	Alu	AluJb
CAediting_690360	chr9_75141158_+	SINE	Alu	AluJb
CAediting_690361	chr9_75141160_+	SINE	Alu	AluJb
CAediting_690362	chr9_75141180_+	SINE	Alu	AluJb
CAediting_690363	chr9_75141190_+	SINE	Alu	AluJb
CAediting_690364	chr9_75141194_+	SINE	Alu	AluJb
CAediting_690365	chr9_75141197_+	SINE	Alu	AluJb
CAediting_690366	chr9_75141203_+	SINE	Alu	AluJb
CAediting_690367	chr9_75141215_+	SINE	Alu	AluJb
CAediting_690368	chr9_75141220_+	SINE	Alu	AluJb
CAediting_690369	chr9_75141229_+	SINE	Alu	AluJb
CAediting_690370	chr9_75141242_+	SINE	Alu	AluJb
CAediting_690371	chr9_75141246_+	SINE	Alu	AluJb
CAediting_690372	chr9_75141258_+	SINE	Alu	AluJb
CAediting_690373	chr9_75141286_+	SINE	Alu	AluJb
CAediting_690374	chr9_75141287_+	SINE	Alu	AluJb
CAediting_690375	chr9_75141779_+	SINE	Alu	AluJr
CAediting_690376	chr9_75141811_+	SINE	Alu	AluJr
CAediting_690377	chr9_75141887_+	SINE	Alu	AluJr
CAediting_690378	chr9_75141909_+	SINE	Alu	AluJr
CAediting_690379	chr9_75141969_+	SINE	Alu	AluJr
CAediting_690380	chr9_75142000_+	SINE	Alu	AluJr
CAediting_690381	chr9_75142010_+	SINE	Alu	AluJr
CAediting_690382	chr9_75143003_+	SINE	Alu	AluSz
CAediting_690383	chr9_75144294_+	SINE	Alu	AluJr
CAediting_690384	chr9_75144321_+	SINE	Alu	AluJr
CAediting_690385	chr9_75144349_+	SINE	Alu	AluJr
CAediting_690386	chr9_75144369_+	SINE	Alu	AluJr
CAediting_690387	chr9_75144431_+	SINE	Alu	AluJr
CAediting_690388	chr9_75144467_+	SINE	Alu	AluJr
CAediting_690389	chr9_75144477_+	SINE	Alu	AluJr

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RNA A-to-I editing events in the alternative splicing sites for OSTF1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000134996.11.OSTF1.

Correlation between RNA A-to-I editing and PSI for ENSG00000134996.11.OSTF1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for OSTF1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ESCA.CAediting_690359.ENSG00000134996.OSTF1.png
Soverview

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Protein coding region RNA A-to-I editings for OSTF1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for OSTF1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for OSTF1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for OSTF1

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for OSTF1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for OSTF1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for OSTF1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for OSTF1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene