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Editing gene: GATM (CAeditome ID:2628)

Gene summary for GATM

Gene summary

Gene information	Gene symbol	GATM
	Gene ID	2628
	Gene name	glycine amidinotransferase
	Synonyms	AGAT\|AT\|CCDS3\|FRTS1
	Cytomap	15q21.1
	Type of gene	protein-coding
	Description	glycine amidinotransferase, mitochondrialglycine amidinotransferase (L-arginine:glycine amidinotransferase)testicular secretory protein Li 19transamidinase
	Modification date	20210518
	UniProtAcc	P50440
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
GATM	GO:0006601	Glycine amidinotransferase, mitochondrial	9218780
GATM	GO:0015068	Glycine amidinotransferase, mitochondrial	27233232
GATM	GO:0015068	Glycine amidinotransferase, mitochondrial	9218780
GATM	GO:0005739	Glycine amidinotransferase, mitochondrial	0000052
GATM	GO:0005758	Glycine amidinotransferase, mitochondrial	9218780

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RNA A-to-I events for GATM

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000171766.14

RNA A-to-I editing events in Cancer.

CAediting_1037337(45363065, -), CAediting_1037338(45363066, -), CAediting_1037339(45363071, -), CAediting_1037340(45363107, -), CAediting_1037341(45363147, -), CAediting_1037342(45363261, -), CAediting_1037343(45364404, -), CAediting_1037344(45364509, -), CAediting_1037345(45368491, -), CAediting_1037346(45368497, -), CAediting_1037347(45370207, -), CAediting_1037348(45370210, -), CAediting_1037349(45370264, -), CAediting_1037350(45370293, -), CAediting_1037351(45370912, -), CAediting_1037352(45371046, -), CAediting_1037353(45373502, -), CAediting_1037354(45378217, -), CAediting_1037355(45382395, -), CAediting_1037356(45382419, -), CAediting_1037357(45382432, -), CAediting_1037358(45382436, -), CAediting_1037359(45382445, -), CAediting_1037360(45382457, -), CAediting_1037361(45382470, -), CAediting_1037362(45382479, -), CAediting_1037363(45382496, -), CAediting_1037364(45382513, -), CAediting_1037365(45382540, -), CAediting_1037366(45382550, -), CAediting_1037367(45382562, -), CAediting_1037368(45382575, -), CAediting_1037369(45382576, -), CAediting_1037370(45382579, -), CAediting_1037371(45382610, -), CAediting_1037372(45382623, -), CAediting_1037373(45382627, -), CAediting_1037374(45382630, -), CAediting_1037375(45382636, -), CAediting_1037376(45382644, -), CAediting_1037377(45382645, -), CAediting_1037378(45382669, -), CAediting_1037379(45382671, -), CAediting_1037380(45382681, -), CAediting_1037381(45382693, -), CAediting_1037382(45382724, -), CAediting_1037383(45382730, -), CAediting_1037384(45382731, -), CAediting_1037385(45382736, -), CAediting_1037386(45382746, -), CAediting_1037387(45382749, -), CAediting_1037388(45382788, -), CAediting_1037389(45383708, -), CAediting_1037390(45383726, -), CAediting_1037391(45383732, -), CAediting_1037392(45383737, -), CAediting_1037393(45383809, -), CAediting_1037394(45383814, -), CAediting_1037395(45383815, -), CAediting_1037396(45384742, -), CAediting_1037397(45384785, -), CAediting_1037398(45384792, -), CAediting_1037399(45384806, -), CAediting_1037400(45384847, -), CAediting_1037401(45384853, -), CAediting_1037402(45384867, -), CAediting_1037403(45384871, -), CAediting_1037404(45384882, -), CAediting_1037405(45384884, -), CAediting_1037406(45384896, -), CAediting_1037407(45384907, -), CAediting_1037408(45384911, -), CAediting_1037409(45384916, -), CAediting_1037410(45384935, -), CAediting_1037411(45384980, -), CAediting_1037412(45384981, -), CAediting_1037413(45384987, -), CAediting_1037414(45389474, -), CAediting_1037415(45389479, -), CAediting_1037416(45389511, -), CAediting_1037417(45389516, -), CAediting_1037418(45389520, -), CAediting_1037419(45389546, -), CAediting_1037420(45389552, -), CAediting_1037421(45389568, -), CAediting_1037422(45389576, -), CAediting_1037423(45389956, -), CAediting_1037424(45389957, -), CAediting_1037425(45389968, -), CAediting_1037426(45389977, -), CAediting_1037427(45390016, -), CAediting_1037428(45390022, -), CAediting_1037429(45390030, -), CAediting_1037430(45390034, -), CAediting_1037431(45390046, -), CAediting_1037432(45390047, -), CAediting_1037433(45390048, -), CAediting_1037434(45390055, -), CAediting_1037435(45390070, -), CAediting_1037436(45390084, -), CAediting_1037437(45390098, -), CAediting_1037438(45390116, -), CAediting_1037439(45390124, -), CAediting_1037440(45390125, -), CAediting_1037441(45391148, -), CAediting_1037442(45391179, -), CAediting_1037443(45391188, -), CAediting_1037444(45391290, -), CAediting_1037445(45391325, -), CAediting_1037446(45391355, -), CAediting_1037447(45391390, -),

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RNA editing positional annotations for GATM using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1037337	chr15_45363065_-	ncRNA_intronic
CAediting_1037338	chr15_45363066_-	ncRNA_intronic
CAediting_1037339	chr15_45363071_-	ncRNA_intronic
CAediting_1037340	chr15_45363107_-	ncRNA_intronic
CAediting_1037341	chr15_45363147_-	ncRNA_intronic
CAediting_1037342	chr15_45363261_-	ncRNA_intronic
CAediting_1037343	chr15_45364404_-	ncRNA_exonic
CAediting_1037344	chr15_45364509_-	ncRNA_exonic
CAediting_1037345	chr15_45368491_-	ncRNA_intronic
CAediting_1037346	chr15_45368497_-	ncRNA_intronic
CAediting_1037347	chr15_45370207_-	ncRNA_intronic
CAediting_1037348	chr15_45370210_-	ncRNA_intronic
CAediting_1037349	chr15_45370264_-	ncRNA_intronic
CAediting_1037350	chr15_45370293_-	ncRNA_intronic
CAediting_1037351	chr15_45370912_-	ncRNA_intronic
CAediting_1037352	chr15_45371046_-	ncRNA_intronic
CAediting_1037353	chr15_45373502_-	ncRNA_intronic
CAediting_1037354	chr15_45378217_-	ncRNA_exonic
CAediting_1037355	chr15_45382395_-	ncRNA_intronic
CAediting_1037356	chr15_45382419_-	ncRNA_intronic
CAediting_1037357	chr15_45382432_-	ncRNA_intronic
CAediting_1037358	chr15_45382436_-	ncRNA_intronic
CAediting_1037359	chr15_45382445_-	ncRNA_intronic
CAediting_1037360	chr15_45382457_-	ncRNA_intronic
CAediting_1037361	chr15_45382470_-	ncRNA_intronic
CAediting_1037362	chr15_45382479_-	ncRNA_intronic
CAediting_1037363	chr15_45382496_-	ncRNA_intronic
CAediting_1037364	chr15_45382513_-	ncRNA_intronic
CAediting_1037365	chr15_45382540_-	ncRNA_intronic
CAediting_1037366	chr15_45382550_-	ncRNA_intronic
CAediting_1037367	chr15_45382562_-	ncRNA_intronic
CAediting_1037368	chr15_45382575_-	ncRNA_intronic
CAediting_1037369	chr15_45382576_-	ncRNA_intronic
CAediting_1037370	chr15_45382579_-	ncRNA_intronic
CAediting_1037371	chr15_45382610_-	ncRNA_intronic
CAediting_1037372	chr15_45382623_-	ncRNA_intronic
CAediting_1037373	chr15_45382627_-	ncRNA_intronic
CAediting_1037374	chr15_45382630_-	ncRNA_intronic
CAediting_1037375	chr15_45382636_-	ncRNA_intronic
CAediting_1037376	chr15_45382644_-	ncRNA_intronic
CAediting_1037377	chr15_45382645_-	ncRNA_intronic
CAediting_1037378	chr15_45382669_-	ncRNA_intronic
CAediting_1037379	chr15_45382671_-	ncRNA_intronic
CAediting_1037380	chr15_45382681_-	ncRNA_intronic
CAediting_1037381	chr15_45382693_-	ncRNA_intronic
CAediting_1037382	chr15_45382724_-	ncRNA_intronic
CAediting_1037383	chr15_45382730_-	ncRNA_intronic
CAediting_1037384	chr15_45382731_-	ncRNA_intronic
CAediting_1037385	chr15_45382736_-	ncRNA_intronic
CAediting_1037386	chr15_45382746_-	ncRNA_intronic
CAediting_1037387	chr15_45382749_-	ncRNA_intronic
CAediting_1037388	chr15_45382788_-	ncRNA_intronic
CAediting_1037389	chr15_45383708_-	ncRNA_intronic
CAediting_1037390	chr15_45383726_-	ncRNA_intronic
CAediting_1037391	chr15_45383732_-	ncRNA_intronic
CAediting_1037392	chr15_45383737_-	ncRNA_intronic
CAediting_1037393	chr15_45383809_-	ncRNA_intronic
CAediting_1037394	chr15_45383814_-	ncRNA_intronic
CAediting_1037395	chr15_45383815_-	ncRNA_intronic
CAediting_1037396	chr15_45384742_-	ncRNA_intronic
CAediting_1037397	chr15_45384785_-	ncRNA_intronic
CAediting_1037398	chr15_45384792_-	ncRNA_intronic
CAediting_1037399	chr15_45384806_-	ncRNA_intronic
CAediting_1037400	chr15_45384847_-	ncRNA_intronic
CAediting_1037401	chr15_45384853_-	ncRNA_intronic
CAediting_1037402	chr15_45384867_-	ncRNA_intronic
CAediting_1037403	chr15_45384871_-	ncRNA_intronic
CAediting_1037404	chr15_45384882_-	ncRNA_intronic
CAediting_1037405	chr15_45384884_-	ncRNA_intronic
CAediting_1037406	chr15_45384896_-	ncRNA_intronic
CAediting_1037407	chr15_45384907_-	ncRNA_intronic
CAediting_1037408	chr15_45384911_-	ncRNA_intronic
CAediting_1037409	chr15_45384916_-	ncRNA_intronic
CAediting_1037410	chr15_45384935_-	ncRNA_intronic
CAediting_1037411	chr15_45384980_-	ncRNA_intronic
CAediting_1037412	chr15_45384981_-	ncRNA_intronic
CAediting_1037413	chr15_45384987_-	ncRNA_intronic
CAediting_1037414	chr15_45389474_-	ncRNA_intronic
CAediting_1037415	chr15_45389479_-	ncRNA_intronic
CAediting_1037416	chr15_45389511_-	ncRNA_intronic
CAediting_1037417	chr15_45389516_-	ncRNA_intronic
CAediting_1037418	chr15_45389520_-	ncRNA_intronic
CAediting_1037419	chr15_45389546_-	ncRNA_intronic
CAediting_1037420	chr15_45389552_-	ncRNA_intronic
CAediting_1037421	chr15_45389568_-	ncRNA_intronic
CAediting_1037422	chr15_45389576_-	ncRNA_intronic
CAediting_1037423	chr15_45389956_-	ncRNA_intronic
CAediting_1037424	chr15_45389957_-	ncRNA_intronic
CAediting_1037425	chr15_45389968_-	ncRNA_intronic
CAediting_1037426	chr15_45389977_-	ncRNA_intronic
CAediting_1037427	chr15_45390016_-	ncRNA_intronic
CAediting_1037428	chr15_45390022_-	ncRNA_intronic
CAediting_1037429	chr15_45390030_-	ncRNA_intronic
CAediting_1037430	chr15_45390034_-	ncRNA_intronic
CAediting_1037431	chr15_45390046_-	ncRNA_intronic
CAediting_1037432	chr15_45390047_-	ncRNA_intronic
CAediting_1037433	chr15_45390048_-	ncRNA_intronic
CAediting_1037434	chr15_45390055_-	ncRNA_intronic
CAediting_1037435	chr15_45390070_-	ncRNA_intronic
CAediting_1037436	chr15_45390084_-	ncRNA_intronic
CAediting_1037437	chr15_45390098_-	ncRNA_intronic
CAediting_1037438	chr15_45390116_-	ncRNA_intronic
CAediting_1037439	chr15_45390124_-	ncRNA_intronic
CAediting_1037440	chr15_45390125_-	ncRNA_intronic
CAediting_1037441	chr15_45391148_-	ncRNA_intronic
CAediting_1037442	chr15_45391179_-	ncRNA_intronic
CAediting_1037443	chr15_45391188_-	ncRNA_intronic
CAediting_1037444	chr15_45391290_-	ncRNA_intronic
CAediting_1037445	chr15_45391325_-	ncRNA_intronic
CAediting_1037446	chr15_45391355_-	ncRNA_intronic
CAediting_1037447	chr15_45391390_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1037337	chr15_45363065_-	SINE	Alu	AluSz
CAediting_1037338	chr15_45363066_-	SINE	Alu	AluSz
CAediting_1037339	chr15_45363071_-	SINE	Alu	AluSz
CAediting_1037340	chr15_45363107_-	SINE	Alu	AluSz
CAediting_1037341	chr15_45363147_-	SINE	Alu	AluSz
CAediting_1037342	chr15_45363261_-	SINE	Alu	AluSz
CAediting_1037343	chr15_45364404_-	SINE	Alu	AluJo
CAediting_1037344	chr15_45364509_-	SINE	Alu	AluJo
CAediting_1037345	chr15_45368491_-	SINE	Alu	AluSz
CAediting_1037346	chr15_45368497_-	SINE	Alu	AluSz
CAediting_1037347	chr15_45370207_-	SINE	Alu	AluSz
CAediting_1037348	chr15_45370210_-	SINE	Alu	AluSz
CAediting_1037349	chr15_45370264_-	SINE	Alu	AluSz
CAediting_1037350	chr15_45370293_-	SINE	Alu	AluSz
CAediting_1037351	chr15_45370912_-	SINE	Alu	AluSx3
CAediting_1037352	chr15_45371046_-	SINE	Alu	AluSx3
CAediting_1037353	chr15_45373502_-	SINE	Alu	AluY
CAediting_1037355	chr15_45382395_-	SINE	Alu	AluSx
CAediting_1037356	chr15_45382419_-	SINE	Alu	AluSx
CAediting_1037357	chr15_45382432_-	SINE	Alu	AluSx
CAediting_1037358	chr15_45382436_-	SINE	Alu	AluSx
CAediting_1037359	chr15_45382445_-	SINE	Alu	AluSx
CAediting_1037360	chr15_45382457_-	SINE	Alu	AluSx
CAediting_1037361	chr15_45382470_-	SINE	Alu	AluSx
CAediting_1037362	chr15_45382479_-	SINE	Alu	AluSx
CAediting_1037363	chr15_45382496_-	SINE	Alu	AluSx
CAediting_1037364	chr15_45382513_-	SINE	Alu	AluSx
CAediting_1037365	chr15_45382540_-	SINE	Alu	AluSz6
CAediting_1037366	chr15_45382550_-	SINE	Alu	AluSz6
CAediting_1037367	chr15_45382562_-	SINE	Alu	AluSz6
CAediting_1037368	chr15_45382575_-	SINE	Alu	AluSz6
CAediting_1037369	chr15_45382576_-	SINE	Alu	AluSz6
CAediting_1037370	chr15_45382579_-	SINE	Alu	AluSz6
CAediting_1037371	chr15_45382610_-	SINE	Alu	AluSz6
CAediting_1037372	chr15_45382623_-	SINE	Alu	AluSz6
CAediting_1037373	chr15_45382627_-	SINE	Alu	AluSz6
CAediting_1037374	chr15_45382630_-	SINE	Alu	AluSz6
CAediting_1037375	chr15_45382636_-	SINE	Alu	AluSz6
CAediting_1037376	chr15_45382644_-	SINE	Alu	AluSz6
CAediting_1037377	chr15_45382645_-	SINE	Alu	AluSz6
CAediting_1037378	chr15_45382669_-	SINE	Alu	AluSz6
CAediting_1037379	chr15_45382671_-	SINE	Alu	AluSz6
CAediting_1037380	chr15_45382681_-	SINE	Alu	AluSz6
CAediting_1037381	chr15_45382693_-	SINE	Alu	AluSz6
CAediting_1037382	chr15_45382724_-	SINE	Alu	AluSz6
CAediting_1037383	chr15_45382730_-	SINE	Alu	AluSz6
CAediting_1037384	chr15_45382731_-	SINE	Alu	AluSz6
CAediting_1037385	chr15_45382736_-	SINE	Alu	AluSz6
CAediting_1037386	chr15_45382746_-	SINE	Alu	AluSz6
CAediting_1037387	chr15_45382749_-	SINE	Alu	AluSz6
CAediting_1037388	chr15_45382788_-	SINE	Alu	AluSz6
CAediting_1037389	chr15_45383708_-	SINE	Alu	AluSx4
CAediting_1037390	chr15_45383726_-	SINE	Alu	AluSx4
CAediting_1037391	chr15_45383732_-	SINE	Alu	AluSx4
CAediting_1037392	chr15_45383737_-	SINE	Alu	AluSx4
CAediting_1037393	chr15_45383809_-	SINE	Alu	AluSx4
CAediting_1037394	chr15_45383814_-	SINE	Alu	AluSx4
CAediting_1037395	chr15_45383815_-	SINE	Alu	AluSx4
CAediting_1037396	chr15_45384742_-	SINE	Alu	AluJb
CAediting_1037397	chr15_45384785_-	SINE	Alu	AluJb
CAediting_1037398	chr15_45384792_-	SINE	Alu	AluJb
CAediting_1037399	chr15_45384806_-	SINE	Alu	AluJb
CAediting_1037400	chr15_45384847_-	SINE	Alu	AluJb
CAediting_1037401	chr15_45384853_-	SINE	Alu	AluJb
CAediting_1037402	chr15_45384867_-	SINE	Alu	AluJb
CAediting_1037403	chr15_45384871_-	SINE	Alu	AluJb
CAediting_1037404	chr15_45384882_-	SINE	Alu	AluJb
CAediting_1037405	chr15_45384884_-	SINE	Alu	AluJb
CAediting_1037406	chr15_45384896_-	SINE	Alu	AluJb
CAediting_1037407	chr15_45384907_-	SINE	Alu	AluJb
CAediting_1037408	chr15_45384911_-	SINE	Alu	AluJb
CAediting_1037409	chr15_45384916_-	SINE	Alu	AluJb
CAediting_1037410	chr15_45384935_-	SINE	Alu	AluJb
CAediting_1037411	chr15_45384980_-	SINE	Alu	AluJb
CAediting_1037412	chr15_45384981_-	SINE	Alu	AluJb
CAediting_1037413	chr15_45384987_-	SINE	Alu	AluJb
CAediting_1037414	chr15_45389474_-	SINE	Alu	AluJb
CAediting_1037415	chr15_45389479_-	SINE	Alu	AluJb
CAediting_1037416	chr15_45389511_-	SINE	Alu	AluJb
CAediting_1037417	chr15_45389516_-	SINE	Alu	AluJb
CAediting_1037418	chr15_45389520_-	SINE	Alu	AluJb
CAediting_1037419	chr15_45389546_-	SINE	Alu	AluJb
CAediting_1037420	chr15_45389552_-	SINE	Alu	AluJb
CAediting_1037421	chr15_45389568_-	SINE	Alu	AluJb
CAediting_1037422	chr15_45389576_-	SINE	Alu	AluJb
CAediting_1037423	chr15_45389956_-	SINE	Alu	AluSz6
CAediting_1037424	chr15_45389957_-	SINE	Alu	AluSz6
CAediting_1037425	chr15_45389968_-	SINE	Alu	AluSz6
CAediting_1037426	chr15_45389977_-	SINE	Alu	AluSz6
CAediting_1037427	chr15_45390016_-	SINE	Alu	AluSz6
CAediting_1037428	chr15_45390022_-	SINE	Alu	AluSz6
CAediting_1037429	chr15_45390030_-	SINE	Alu	AluSz6
CAediting_1037430	chr15_45390034_-	SINE	Alu	AluSz6
CAediting_1037431	chr15_45390046_-	SINE	Alu	AluSz6
CAediting_1037432	chr15_45390047_-	SINE	Alu	AluSz6
CAediting_1037433	chr15_45390048_-	SINE	Alu	AluSz6
CAediting_1037434	chr15_45390055_-	SINE	Alu	AluSz6
CAediting_1037435	chr15_45390070_-	SINE	Alu	AluSz6
CAediting_1037436	chr15_45390084_-	SINE	Alu	AluSz6
CAediting_1037437	chr15_45390098_-	SINE	Alu	AluSz6
CAediting_1037438	chr15_45390116_-	SINE	Alu	AluSz6
CAediting_1037439	chr15_45390124_-	SINE	Alu	AluSz6
CAediting_1037440	chr15_45390125_-	SINE	Alu	AluSz6
CAediting_1037441	chr15_45391148_-	SINE	Alu	AluSx
CAediting_1037442	chr15_45391179_-	SINE	Alu	AluSx
CAediting_1037443	chr15_45391188_-	SINE	Alu	AluSx
CAediting_1037444	chr15_45391290_-	SINE	Alu	AluSx
CAediting_1037445	chr15_45391325_-	SINE	Alu	AluSx
CAediting_1037446	chr15_45391355_-	SINE	Alu	AluSx
CAediting_1037447	chr15_45391390_-	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for GATM

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000171766.14.GATM.

Correlation between RNA A-to-I editing and PSI for ENSG00000171766.14.GATM.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GATM

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for GATM

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for GATM

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1160181	chr17_7017644_-	ENSG00000171766.14	ENST00000396659	hsa-miR-195-3p	45361464	45361470	7mer-m8	45361463	45361485	150	-11.98

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_688080	chr9_63819626_+	ENSG00000171766.14	ENST00000396659	hsa-miR-4477b	45361329	45361335	7mer-m8	45361328	45361346	144	-10.57
CAediting_688081	chr9_63819627_+	ENSG00000171766.14	ENST00000396659	hsa-miR-4477b	45361329	45361335	7mer-m8	45361328	45361346	144	-10.57

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GATM

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for GATM

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for GATM

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRC	pathologic_stage	CAediting_1037407	chr15_45384907_-	2.03238582140238e-05	0.311834943836639
KIRC	pathologic_stage	CAediting_1037411	chr15_45384980_-	2.96806375102673e-05	0.299534369584756
KIRC	pathologic_stage	CAediting_1037412	chr15_45384981_-	5.71283608810218e-05	0.294507861372626

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Relation with survival for GATM

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for GATM

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
GATM	P50440	DB02530	gamma-Aminobutyric acid	Glycine amidinotransferase, mitochondrial	SmallMoleculeDrug	approved\|investigational
GATM	P50440	DB00129	Ornithine	Glycine amidinotransferase, mitochondrial	SmallMoleculeDrug	approved\|nutraceutical
GATM	P50440	DB00145	Glycine	Glycine amidinotransferase, mitochondrial	SmallMoleculeDrug	approved\|nutraceutical\|vet_approved

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RelatedDiseases for GATM

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
GATM	C2675179	Arginine:Glycine Amidinotransferase Deficiency	17	CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT
GATM	C0007097	Carcinoma	1	CTD_human
GATM	C0018801	Heart failure	1	CTD_human
GATM	C0018802	Congestive heart failure	1	CTD_human
GATM	C0022658	Kidney Diseases	1	CTD_human
GATM	C0023212	Left-Sided Heart Failure	1	CTD_human
GATM	C0024667	Animal Mammary Neoplasms	1	CTD_human
GATM	C0024668	Mammary Neoplasms, Experimental	1	CTD_human
GATM	C0027540	Necrosis	1	CTD_human
GATM	C0151744	Myocardial Ischemia	1	CTD_human
GATM	C0205696	Anaplastic carcinoma	1	CTD_human
GATM	C0205697	Carcinoma, Spindle-Cell	1	CTD_human
GATM	C0205698	Undifferentiated carcinoma	1	CTD_human
GATM	C0205699	Carcinomatosis	1	CTD_human
GATM	C0235527	Heart Failure, Right-Sided	1	CTD_human
GATM	C1257925	Mammary Carcinoma, Animal	1	CTD_human
GATM	C1959583	Myocardial Failure	1	CTD_human
GATM	C1961112	Heart Decompensation	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene