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Editing gene: FBXO9 (CAeditome ID:26268)

Gene summary for FBXO9

Gene summary

Gene information	Gene symbol	FBXO9
	Gene ID	26268
	Gene name	F-box protein 9
	Synonyms	FBX9\|NY-REN-57\|VCIA1\|dJ341E18.2
	Cytomap	6p12.1
	Type of gene	protein-coding
	Description	F-box only protein 9F-box protein Fbx9cross-immune reaction antigen 1renal carcinoma antigen NY-REN-57
	Modification date	20210518
	UniProtAcc	Q9UK97
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
FBXO9	GO:0016567	F-box only protein 9	23263282
FBXO9	GO:0031146	F-box only protein 9	23263282
FBXO9	GO:0005737	F-box only protein 9	23263282
FBXO9	GO:0019005	F-box only protein 9	23263282

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RNA A-to-I events for FBXO9

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000112146.15

RNA A-to-I editing events in Cancer.

CAediting_486865(53069024, +), CAediting_486866(53075337, +), CAediting_486867(53075348, +), CAediting_486868(53075351, +), CAediting_486869(53075373, +), CAediting_486870(53075376, +), CAediting_486871(53075387, +), CAediting_486872(53075414, +), CAediting_486873(53075996, +), CAediting_486874(53076006, +), CAediting_486875(53076018, +), CAediting_486876(53076020, +), CAediting_486877(53076027, +), CAediting_486878(53076031, +), CAediting_486879(53076044, +), CAediting_486880(53076052, +), CAediting_486881(53076076, +), CAediting_486882(53081984, +), CAediting_486883(53086026, +), CAediting_486884(53086792, +), CAediting_486885(53086812, +), CAediting_486886(53086813, +), CAediting_486887(53086834, +), CAediting_486888(53086835, +), CAediting_486889(53086839, +), CAediting_486890(53086858, +), CAediting_486891(53086894, +), CAediting_486892(53086895, +), CAediting_486893(53086896, +), CAediting_486894(53086897, +), CAediting_486895(53086898, +), CAediting_486896(53086902, +), CAediting_486897(53086903, +), CAediting_486898(53086904, +), CAediting_486899(53086905, +), CAediting_486900(53086906, +), CAediting_486901(53086907, +), CAediting_486902(53086910, +), CAediting_486903(53086950, +), CAediting_486904(53086955, +), CAediting_486905(53086959, +), CAediting_486906(53086994, +), CAediting_486907(53087010, +), CAediting_486908(53087019, +), CAediting_486909(53087070, +), CAediting_486910(53087078, +), CAediting_486911(53087080, +), CAediting_486912(53087084, +), CAediting_486913(53087086, +), CAediting_486914(53087143, +), CAediting_486915(53087152, +), CAediting_486916(53087161, +), CAediting_486917(53087166, +), CAediting_486918(53087185, +), CAediting_486919(53087187, +), CAediting_486920(53087192, +), CAediting_486921(53087196, +), CAediting_486922(53087202, +), CAediting_486923(53087206, +), CAediting_486924(53087215, +), CAediting_486925(53087227, +), CAediting_486926(53087231, +), CAediting_486927(53087235, +), CAediting_486928(53087238, +), CAediting_486929(53087244, +), CAediting_486930(53087248, +), CAediting_486931(53087275, +), CAediting_486932(53087286, +), CAediting_486933(53087297, +), CAediting_486934(53087302, +), CAediting_486935(53087307, +), CAediting_486936(53087317, +), CAediting_486937(53087329, +), CAediting_486938(53087330, +), CAediting_486939(53087349, +), CAediting_486940(53088630, +), CAediting_486941(53088698, +), CAediting_486942(53088716, +), CAediting_486943(53089241, +), CAediting_486944(53089282, +), CAediting_486945(53089353, +), CAediting_486946(53090700, +), CAediting_486947(53090705, +), CAediting_486948(53090748, +), CAediting_486949(53090780, +), CAediting_486950(53090988, +), CAediting_486951(53091004, +), CAediting_486952(53091010, +), CAediting_486953(53091019, +), CAediting_486954(53091034, +), CAediting_486955(53091462, +), CAediting_486956(53091469, +), CAediting_486957(53091558, +), CAediting_486958(53091643, +), CAediting_486959(53099131, +), CAediting_486960(53099153, +), CAediting_486961(53099164, +), CAediting_486962(53099272, +), CAediting_486963(53099289, +), CAediting_486964(53099322, +), CAediting_486965(53099328, +), CAediting_486966(53099338, +), CAediting_486967(53099342, +), CAediting_486968(53099477, +), CAediting_486969(53099486, +), CAediting_486970(53099492, +), CAediting_486971(53099512, +), CAediting_486972(53099633, +), CAediting_486973(53099659, +), CAediting_486974(53099726, +), CAediting_486975(53100519, +), CAediting_486976(53100576, +),

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RNA editing positional annotations for FBXO9 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_486865	chr6_53069024_+	intronic
CAediting_486866	chr6_53075337_+	ncRNA_intronic
CAediting_486867	chr6_53075348_+	ncRNA_intronic
CAediting_486868	chr6_53075351_+	ncRNA_intronic
CAediting_486869	chr6_53075373_+	ncRNA_intronic
CAediting_486870	chr6_53075376_+	ncRNA_intronic
CAediting_486871	chr6_53075387_+	ncRNA_intronic
CAediting_486872	chr6_53075414_+	ncRNA_intronic
CAediting_486873	chr6_53075996_+	ncRNA_intronic
CAediting_486874	chr6_53076006_+	ncRNA_intronic
CAediting_486875	chr6_53076018_+	ncRNA_intronic
CAediting_486876	chr6_53076020_+	ncRNA_intronic
CAediting_486877	chr6_53076027_+	ncRNA_intronic
CAediting_486878	chr6_53076031_+	ncRNA_intronic
CAediting_486879	chr6_53076044_+	ncRNA_intronic
CAediting_486880	chr6_53076052_+	ncRNA_intronic
CAediting_486881	chr6_53076076_+	ncRNA_intronic
CAediting_486882	chr6_53081984_+	ncRNA_intronic
CAediting_486883	chr6_53086026_+	ncRNA_intronic
CAediting_486884	chr6_53086792_+	ncRNA_intronic
CAediting_486885	chr6_53086812_+	ncRNA_intronic
CAediting_486886	chr6_53086813_+	ncRNA_intronic
CAediting_486887	chr6_53086834_+	ncRNA_intronic
CAediting_486888	chr6_53086835_+	ncRNA_intronic
CAediting_486889	chr6_53086839_+	ncRNA_intronic
CAediting_486890	chr6_53086858_+	ncRNA_intronic
CAediting_486891	chr6_53086894_+	ncRNA_intronic
CAediting_486892	chr6_53086895_+	ncRNA_intronic
CAediting_486893	chr6_53086896_+	ncRNA_intronic
CAediting_486894	chr6_53086897_+	ncRNA_intronic
CAediting_486895	chr6_53086898_+	ncRNA_intronic
CAediting_486896	chr6_53086902_+	ncRNA_intronic
CAediting_486897	chr6_53086903_+	ncRNA_intronic
CAediting_486898	chr6_53086904_+	ncRNA_intronic
CAediting_486899	chr6_53086905_+	ncRNA_intronic
CAediting_486900	chr6_53086906_+	ncRNA_intronic
CAediting_486901	chr6_53086907_+	ncRNA_intronic
CAediting_486902	chr6_53086910_+	ncRNA_intronic
CAediting_486903	chr6_53086950_+	ncRNA_intronic
CAediting_486904	chr6_53086955_+	ncRNA_intronic
CAediting_486905	chr6_53086959_+	ncRNA_intronic
CAediting_486906	chr6_53086994_+	ncRNA_intronic
CAediting_486907	chr6_53087010_+	ncRNA_intronic
CAediting_486908	chr6_53087019_+	ncRNA_intronic
CAediting_486909	chr6_53087070_+	ncRNA_intronic
CAediting_486910	chr6_53087078_+	ncRNA_intronic
CAediting_486911	chr6_53087080_+	ncRNA_intronic
CAediting_486912	chr6_53087084_+	ncRNA_intronic
CAediting_486913	chr6_53087086_+	ncRNA_intronic
CAediting_486914	chr6_53087143_+	ncRNA_intronic
CAediting_486915	chr6_53087152_+	ncRNA_intronic
CAediting_486916	chr6_53087161_+	ncRNA_intronic
CAediting_486917	chr6_53087166_+	ncRNA_intronic
CAediting_486918	chr6_53087185_+	ncRNA_intronic
CAediting_486919	chr6_53087187_+	ncRNA_intronic
CAediting_486920	chr6_53087192_+	ncRNA_intronic
CAediting_486921	chr6_53087196_+	ncRNA_intronic
CAediting_486922	chr6_53087202_+	ncRNA_intronic
CAediting_486923	chr6_53087206_+	ncRNA_intronic
CAediting_486924	chr6_53087215_+	ncRNA_intronic
CAediting_486925	chr6_53087227_+	ncRNA_intronic
CAediting_486926	chr6_53087231_+	ncRNA_intronic
CAediting_486927	chr6_53087235_+	ncRNA_intronic
CAediting_486928	chr6_53087238_+	ncRNA_intronic
CAediting_486929	chr6_53087244_+	ncRNA_intronic
CAediting_486930	chr6_53087248_+	ncRNA_intronic
CAediting_486931	chr6_53087275_+	ncRNA_intronic
CAediting_486932	chr6_53087286_+	ncRNA_intronic
CAediting_486933	chr6_53087297_+	ncRNA_intronic
CAediting_486934	chr6_53087302_+	ncRNA_intronic
CAediting_486935	chr6_53087307_+	ncRNA_intronic
CAediting_486936	chr6_53087317_+	ncRNA_intronic
CAediting_486937	chr6_53087329_+	ncRNA_intronic
CAediting_486938	chr6_53087330_+	ncRNA_intronic
CAediting_486939	chr6_53087349_+	ncRNA_intronic
CAediting_486940	chr6_53088630_+	ncRNA_intronic
CAediting_486941	chr6_53088698_+	ncRNA_intronic
CAediting_486942	chr6_53088716_+	ncRNA_intronic
CAediting_486943	chr6_53089241_+	ncRNA_intronic
CAediting_486944	chr6_53089282_+	ncRNA_intronic
CAediting_486945	chr6_53089353_+	ncRNA_intronic
CAediting_486946	chr6_53090700_+	ncRNA_intronic
CAediting_486947	chr6_53090705_+	ncRNA_intronic
CAediting_486948	chr6_53090748_+	ncRNA_intronic
CAediting_486949	chr6_53090780_+	ncRNA_intronic
CAediting_486950	chr6_53090988_+	ncRNA_exonic
CAediting_486951	chr6_53091004_+	ncRNA_exonic
CAediting_486952	chr6_53091010_+	ncRNA_exonic
CAediting_486953	chr6_53091019_+	ncRNA_exonic
CAediting_486954	chr6_53091034_+	ncRNA_exonic
CAediting_486955	chr6_53091462_+	ncRNA_exonic
CAediting_486956	chr6_53091469_+	ncRNA_exonic
CAediting_486957	chr6_53091558_+	ncRNA_exonic
CAediting_486958	chr6_53091643_+	ncRNA_exonic
CAediting_486959	chr6_53099131_+	UTR3
CAediting_486960	chr6_53099153_+	UTR3
CAediting_486961	chr6_53099164_+	UTR3
CAediting_486962	chr6_53099272_+	UTR3
CAediting_486963	chr6_53099289_+	UTR3
CAediting_486964	chr6_53099322_+	UTR3
CAediting_486965	chr6_53099328_+	UTR3
CAediting_486966	chr6_53099338_+	UTR3
CAediting_486967	chr6_53099342_+	UTR3
CAediting_486968	chr6_53099477_+	UTR3
CAediting_486969	chr6_53099486_+	UTR3
CAediting_486970	chr6_53099492_+	UTR3
CAediting_486971	chr6_53099512_+	UTR3
CAediting_486972	chr6_53099633_+	UTR3
CAediting_486973	chr6_53099659_+	UTR3
CAediting_486974	chr6_53099726_+	UTR3
CAediting_486975	chr6_53100519_+	UTR3
CAediting_486976	chr6_53100576_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_486865	chr6_53069024_+	SINE	Alu	FLAM_A
CAediting_486869	chr6_53075373_+	SINE	Alu	FLAM_C
CAediting_486870	chr6_53075376_+	SINE	Alu	FLAM_C
CAediting_486871	chr6_53075387_+	SINE	Alu	FLAM_C
CAediting_486872	chr6_53075414_+	SINE	Alu	FLAM_C
CAediting_486873	chr6_53075996_+	SINE	Alu	AluSx
CAediting_486874	chr6_53076006_+	SINE	Alu	AluSx
CAediting_486875	chr6_53076018_+	SINE	Alu	AluSx
CAediting_486876	chr6_53076020_+	SINE	Alu	AluSx
CAediting_486877	chr6_53076027_+	SINE	Alu	AluSx
CAediting_486878	chr6_53076031_+	SINE	Alu	AluSx
CAediting_486879	chr6_53076044_+	LINE	L1	L1MD
CAediting_486880	chr6_53076052_+	LINE	L1	L1MD
CAediting_486881	chr6_53076076_+	LINE	L1	L1MD
CAediting_486882	chr6_53081984_+	SINE	Alu	AluSz6
CAediting_486883	chr6_53086026_+	SINE	Alu	AluSp
CAediting_486884	chr6_53086792_+	SINE	Alu	AluJr
CAediting_486885	chr6_53086812_+	SINE	Alu	AluJr
CAediting_486886	chr6_53086813_+	SINE	Alu	AluJr
CAediting_486887	chr6_53086834_+	SINE	Alu	AluJr
CAediting_486888	chr6_53086835_+	SINE	Alu	AluJr
CAediting_486889	chr6_53086839_+	SINE	Alu	AluJr
CAediting_486890	chr6_53086858_+	SINE	Alu	AluJr
CAediting_486891	chr6_53086894_+	SINE	Alu	AluJr
CAediting_486892	chr6_53086895_+	SINE	Alu	AluJr
CAediting_486893	chr6_53086896_+	SINE	Alu	AluJr
CAediting_486894	chr6_53086897_+	SINE	Alu	AluJr
CAediting_486895	chr6_53086898_+	SINE	Alu	AluJr
CAediting_486896	chr6_53086902_+	SINE	Alu	AluJr
CAediting_486897	chr6_53086903_+	SINE	Alu	AluJr
CAediting_486898	chr6_53086904_+	SINE	Alu	AluJr
CAediting_486899	chr6_53086905_+	SINE	Alu	AluJr
CAediting_486900	chr6_53086906_+	SINE	Alu	AluJr
CAediting_486901	chr6_53086907_+	SINE	Alu	AluJr
CAediting_486902	chr6_53086910_+	SINE	Alu	AluJr
CAediting_486903	chr6_53086950_+	SINE	Alu	AluJr
CAediting_486904	chr6_53086955_+	SINE	Alu	AluJr
CAediting_486905	chr6_53086959_+	SINE	Alu	AluJr
CAediting_486906	chr6_53086994_+	SINE	Alu	AluJr
CAediting_486907	chr6_53087010_+	SINE	Alu	AluJr
CAediting_486908	chr6_53087019_+	SINE	Alu	AluJr
CAediting_486909	chr6_53087070_+	SINE	Alu	AluJo
CAediting_486910	chr6_53087078_+	SINE	Alu	AluJo
CAediting_486911	chr6_53087080_+	SINE	Alu	AluJo
CAediting_486912	chr6_53087084_+	SINE	Alu	AluJo
CAediting_486913	chr6_53087086_+	SINE	Alu	AluJo
CAediting_486914	chr6_53087143_+	SINE	Alu	AluJo
CAediting_486915	chr6_53087152_+	SINE	Alu	AluJo
CAediting_486916	chr6_53087161_+	SINE	Alu	AluJo
CAediting_486917	chr6_53087166_+	SINE	Alu	AluJo
CAediting_486918	chr6_53087185_+	SINE	Alu	AluJo
CAediting_486919	chr6_53087187_+	SINE	Alu	AluJo
CAediting_486920	chr6_53087192_+	SINE	Alu	AluJo
CAediting_486921	chr6_53087196_+	SINE	Alu	AluJo
CAediting_486922	chr6_53087202_+	SINE	Alu	AluJo
CAediting_486923	chr6_53087206_+	SINE	Alu	AluJo
CAediting_486924	chr6_53087215_+	SINE	Alu	AluJo
CAediting_486925	chr6_53087227_+	SINE	Alu	AluJo
CAediting_486926	chr6_53087231_+	SINE	Alu	AluJo
CAediting_486927	chr6_53087235_+	SINE	Alu	AluJo
CAediting_486928	chr6_53087238_+	SINE	Alu	AluJo
CAediting_486929	chr6_53087244_+	SINE	Alu	AluJo
CAediting_486930	chr6_53087248_+	SINE	Alu	AluJo
CAediting_486931	chr6_53087275_+	SINE	Alu	AluJo
CAediting_486932	chr6_53087286_+	SINE	Alu	AluJo
CAediting_486933	chr6_53087297_+	SINE	Alu	AluJo
CAediting_486934	chr6_53087302_+	SINE	Alu	AluJo
CAediting_486935	chr6_53087307_+	SINE	Alu	AluJo
CAediting_486936	chr6_53087317_+	SINE	Alu	AluJo
CAediting_486937	chr6_53087329_+	SINE	Alu	AluJo
CAediting_486938	chr6_53087330_+	SINE	Alu	AluJo
CAediting_486939	chr6_53087349_+	SINE	Alu	AluJo
CAediting_486940	chr6_53088630_+	SINE	Alu	AluSx
CAediting_486941	chr6_53088698_+	SINE	Alu	AluSx
CAediting_486942	chr6_53088716_+	SINE	Alu	AluSx
CAediting_486943	chr6_53089241_+	SINE	Alu	AluY
CAediting_486944	chr6_53089282_+	SINE	Alu	AluY
CAediting_486945	chr6_53089353_+	SINE	Alu	AluY
CAediting_486946	chr6_53090700_+	SINE	Alu	AluJo
CAediting_486947	chr6_53090705_+	SINE	Alu	AluJo
CAediting_486948	chr6_53090748_+	SINE	Alu	AluJo
CAediting_486949	chr6_53090780_+	SINE	Alu	AluJo
CAediting_486950	chr6_53090988_+	srpRNA	srpRNA	7SLRNA
CAediting_486951	chr6_53091004_+	srpRNA	srpRNA	7SLRNA
CAediting_486952	chr6_53091010_+	srpRNA	srpRNA	7SLRNA
CAediting_486953	chr6_53091019_+	srpRNA	srpRNA	7SLRNA
CAediting_486954	chr6_53091034_+	srpRNA	srpRNA	7SLRNA
CAediting_486955	chr6_53091462_+	SINE	Alu	AluSg
CAediting_486956	chr6_53091469_+	SINE	Alu	AluSg
CAediting_486957	chr6_53091558_+	SINE	Alu	AluSg
CAediting_486958	chr6_53091643_+	SINE	Alu	AluSg
CAediting_486959	chr6_53099131_+	SINE	Alu	AluJb
CAediting_486960	chr6_53099153_+	SINE	Alu	AluJb
CAediting_486961	chr6_53099164_+	SINE	Alu	AluJb
CAediting_486962	chr6_53099272_+	SINE	Alu	AluJb
CAediting_486963	chr6_53099289_+	SINE	Alu	AluJb
CAediting_486964	chr6_53099322_+	SINE	Alu	AluJb
CAediting_486965	chr6_53099328_+	SINE	Alu	AluJb
CAediting_486966	chr6_53099338_+	SINE	Alu	AluJb
CAediting_486967	chr6_53099342_+	SINE	Alu	AluJb
CAediting_486968	chr6_53099477_+	SINE	Alu	AluJr
CAediting_486969	chr6_53099486_+	SINE	Alu	AluJr
CAediting_486970	chr6_53099492_+	SINE	Alu	AluJr
CAediting_486971	chr6_53099512_+	SINE	Alu	AluJr
CAediting_486972	chr6_53099633_+	SINE	Alu	AluJr
CAediting_486973	chr6_53099659_+	SINE	Alu	AluJr
CAediting_486974	chr6_53099726_+	SINE	Alu	AluJr

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RNA A-to-I editing events in the alternative splicing sites for FBXO9

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000112146.15.FBXO9.

Correlation between RNA A-to-I editing and PSI for ENSG00000112146.15.FBXO9.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for FBXO9

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for FBXO9

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for FBXO9

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_486975	chr6_53100519_+	ENSG00000112146.15	ENST00000244426	hsa-miR-1470	53100517	53100523	7mer-m8	53100504	53100524	145.00	-21.46
CAediting_486959	chr6_53099131_+	ENSG00000112146.15	ENST00000244426	hsa-miR-638	53099130	53099136	7mer-1a	53099112	53099136	147.00	-29.45
CAediting_486961	chr6_53099164_+	ENSG00000112146.15	ENST00000244426	hsa-miR-6747-3p	53099157	53099163	7mer-m8	53099144	53099164	148.00	-21.34
CAediting_486963	chr6_53099289_+	ENSG00000112146.15	ENST00000244426	hsa-miR-3943	53099286	53099292	7mer-m8	53099265	53099293	149.00	-25.64
CAediting_486964	chr6_53099322_+	ENSG00000112146.15	ENST00000244426	hsa-miR-1306-5p	53099318	53099324	7mer-m8	53099304	53099325	151.00	-25.23
CAediting_486967	chr6_53099342_+	ENSG00000112146.15	ENST00000244426	hsa-miR-4638-5p	53099337	53099344	8mer-1a	53099325	53099344	146.00	-20.11
CAediting_486972	chr6_53099633_+	ENSG00000112146.15	ENST00000244426	hsa-miR-1207-3p	53099626	53099632	7mer-m8	53099615	53099633	145.00	-17.25
CAediting_486974	chr6_53099726_+	ENSG00000112146.15	ENST00000244426	hsa-miR-320a-5p	53099720	53099726	7mer-m8	53099706	53099727	161.00	-25.36
CAediting_486974	chr6_53099726_+	ENSG00000112146.15	ENST00000244426	hsa-miR-6880-3p	53099722	53099729	8mer-1a	53099709	53099729	158.00	-24.76
CAediting_486962	chr6_53099272_+	ENSG00000112146.15	ENST00000244426	hsa-miR-591	53099269	53099274	6mer	53099253	53099275	145.00	-27.58
CAediting_486966	chr6_53099338_+	ENSG00000112146.15	ENST00000244426	hsa-miR-324-3p	53099331	53099337	7mer-m8	53099316	53099338	145.00	-21.90
CAediting_486969	chr6_53099486_+	ENSG00000112146.15	ENST00000244426	hsa-miR-625-3p	53099480	53099486	7mer-m8	53099466	53099487	140.00	-12.81
CAediting_486970	chr6_53099492_+	ENSG00000112146.15	ENST00000244426	hsa-miR-1278	53099489	53099495	7mer-m8	53099475	53099496	151.00	-9.50
CAediting_486970	chr6_53099492_+	ENSG00000112146.15	ENST00000244426	hsa-miR-6506-5p	53099485	53099491	7mer-m8	53099470	53099492	140.00	-14.68

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_486962	chr6_53099272_+	ENSG00000112146.15	ENST00000244426	hsa-miR-10525-3p	53099269	53099274	6mer	53099254	53099275	144	-21.01
CAediting_486973	chr6_53099659_+	ENSG00000112146.15	ENST00000244426	hsa-miR-1245a	53099654	53099660	7mer-m8	53099641	53099661	149	-18.39
CAediting_486963	chr6_53099289_+	ENSG00000112146.15	ENST00000244426	hsa-miR-150-5p	53099283	53099289	7mer-m8	53099269	53099290	140	-15.69
CAediting_486971	chr6_53099512_+	ENSG00000112146.15	ENST00000244426	hsa-miR-1976	53099509	53099515	7mer-m8	53099495	53099516	152	-25.54
CAediting_486975	chr6_53100519_+	ENSG00000112146.15	ENST00000244426	hsa-miR-2276-5p	53100517	53100523	7mer-m8	53100503	53100524	143	-17.16
CAediting_486974	chr6_53099726_+	ENSG00000112146.15	ENST00000244426	hsa-miR-3160-5p	53099721	53099727	7mer-m8	53099707	53099728	154	-16.99
CAediting_486974	chr6_53099726_+	ENSG00000112146.15	ENST00000244426	hsa-miR-3160-5p	53099721	53099727	7mer-m8	53099707	53099728	154	-16.99
CAediting_486966	chr6_53099338_+	ENSG00000112146.15	ENST00000244426	hsa-miR-4284	53099334	53099341	8mer-1a	53099324	53099341	146	-13.71
CAediting_486964	chr6_53099322_+	ENSG00000112146.15	ENST00000244426	hsa-miR-4436b-5p	53099320	53099327	8mer-1a	53099307	53099327	150	-19.45
CAediting_486964	chr6_53099322_+	ENSG00000112146.15	ENST00000244426	hsa-miR-4436b-5p	53099320	53099327	8mer-1a	53099307	53099327	150	-19.45
CAediting_486975	chr6_53100519_+	ENSG00000112146.15	ENST00000244426	hsa-miR-4639-5p	53100512	53100518	7mer-m8	53100500	53100519	147	-14.23
CAediting_486972	chr6_53099633_+	ENSG00000112146.15	ENST00000244426	hsa-miR-4661-5p	53099628	53099634	7mer-m8	53099617	53099635	144	-17.36
CAediting_486961	chr6_53099164_+	ENSG00000112146.15	ENST00000244426	hsa-miR-5001-3p	53099157	53099163	7mer-m8	53099145	53099164	148	-18.16
CAediting_486969	chr6_53099486_+	ENSG00000112146.15	ENST00000244426	hsa-miR-5089-5p	53099484	53099491	8mer-1a	53099466	53099491	145	-17.02
CAediting_486970	chr6_53099492_+	ENSG00000112146.15	ENST00000244426	hsa-miR-6513-5p	53099485	53099491	7mer-m8	53099470	53099492	146	-13.92
CAediting_486971	chr6_53099512_+	ENSG00000112146.15	ENST00000244426	hsa-miR-660-3p	53099510	53099517	8mer-1a	53099497	53099517	143	-18.16
CAediting_486975	chr6_53100519_+	ENSG00000112146.15	ENST00000244426	hsa-miR-6728-3p	53100515	53100521	7mer-m8	53100502	53100522	140	-12.75
CAediting_486971	chr6_53099512_+	ENSG00000112146.15	ENST00000244426	hsa-miR-6747-3p	53099507	53099514	8mer-1a	53099493	53099514	154	-24.54
CAediting_486963	chr6_53099289_+	ENSG00000112146.15	ENST00000244426	hsa-miR-6778-3p	53099285	53099291	7mer-m8	53099272	53099292	140	-16.01
CAediting_486963	chr6_53099289_+	ENSG00000112146.15	ENST00000244426	hsa-miR-6791-3p	53099286	53099291	6mer	53099270	53099292	142	-21.49
CAediting_486965	chr6_53099328_+	ENSG00000112146.15	ENST00000244426	hsa-miR-891b	53099326	53099333	8mer-1a	53099311	53099333	143	-14.92
CAediting_486968	chr6_53099477_+	ENSG00000112146.15	ENST00000244426	hsa-miR-937-5p	53099470	53099476	7mer-m8	53099458	53099477	140	-20.04

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000112146.15	ENST00000244426	hsa-miR-624-3p	53099731	53099737	7mer-m8	53099718	53099738	155	-15.38
CAediting_980496	chr14_31014685_-	ENSG00000112146.15	ENST00000244426	hsa-miR-624-3p	53100744	53100750	7mer-1a	53100730	53100750	148	-15.95
CAediting_688080	chr9_63819626_+	ENSG00000112146.15	ENST00000244426	hsa-miR-4477b	53100612	53100618	7mer-m8	53100600	53100619	145	-12.03
CAediting_1229414	chr17_67471546_+	ENSG00000112146.15	ENST00000244426	hsa-miR-548aa	53100238	53100244	7mer-m8	53100221	53100245	147	-11.44
CAediting_1229414	chr17_67471546_+	ENSG00000112146.15	ENST00000244426	hsa-miR-548aa	53098626	53098632	7mer-m8	53098609	53098633	140	-9.63
CAediting_604450	chr7_133034877_-	ENSG00000112146.15	ENST00000244426	hsa-miR-3654	53098554	53098561	8mer-1a	53098541	53098561	148	-16.96
CAediting_468389	chr6_31355314_-	ENSG00000112146.15	ENST00000244426	hsa-miR-6891-5p	53100469	53100475	7mer-m8	53100458	53100476	148	-16.84

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_846604	chr11_93733708_-	ENSG00000112146.15	ENST00000244426	hsa-miR-1304-3p	53099375	53099382	8mer-1a	53099361	53099382	145	-18.67
CAediting_396018	chr5_1062918_-	ENSG00000112146.15	ENST00000244426	hsa-miR-4635	53098719	53098725	7mer-m8	53098706	53098726	145	-13.68
CAediting_1229414	chr17_67471546_+	ENSG00000112146.15	ENST00000244426	hsa-miR-548aa	53098951	53098957	7mer-m8	53098935	53098958	147	-6.61
CAediting_1229415	chr17_67471547_+	ENSG00000112146.15	ENST00000244426	hsa-miR-548aa	53098951	53098957	7mer-m8	53098935	53098958	147	-6.61
CAediting_1229414	chr17_67471546_+	ENSG00000112146.15	ENST00000244426	hsa-miR-548aa	53100814	53100820	7mer-m8	53100797	53100821	152	-6.67
CAediting_1229415	chr17_67471547_+	ENSG00000112146.15	ENST00000244426	hsa-miR-548aa	53100814	53100820	7mer-m8	53100797	53100821	152	-6.67
CAediting_228905	chr2_188297554_+	ENSG00000112146.15	ENST00000244426	hsa-miR-561-3p	53100262	53100268	7mer-m8	53100248	53100269	140	-4.7

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for FBXO9

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000323557.10	protein_coding
ENST00000244426.9	protein_coding
ENST00000474457.1	retained_intron

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_486959	ENST00000323557.10	chr6_53099131_+	-1043.14	-1042.94	-1058.40
CAediting_486960	ENST00000323557.10	chr6_53099153_+	-1045.44	-1042.94	-1058.40
CAediting_486961	ENST00000323557.10	chr6_53099164_+	-1044.04	-1042.94	-1058.40
CAediting_486962	ENST00000323557.10	chr6_53099272_+	-1043.94	-1042.94	-1058.40
CAediting_486963	ENST00000323557.10	chr6_53099289_+	-1042.54	-1042.94	-1058.40
CAediting_486964	ENST00000323557.10	chr6_53099322_+	-1043.50	-1042.94	-1058.40
CAediting_486965	ENST00000323557.10	chr6_53099328_+	-1042.64	-1042.94	-1058.40
CAediting_486966	ENST00000323557.10	chr6_53099338_+	-1042.80	-1042.94	-1058.40
CAediting_486967	ENST00000323557.10	chr6_53099342_+	-1042.94	-1042.94	-1058.40
CAediting_486968	ENST00000323557.10	chr6_53099477_+	-1043.14	-1042.94	-1058.40
CAediting_486969	ENST00000323557.10	chr6_53099486_+	-1042.94	-1042.94	-1058.40
CAediting_486970	ENST00000323557.10	chr6_53099492_+	-1042.44	-1042.94	-1058.40
CAediting_486971	ENST00000323557.10	chr6_53099512_+	-1049.14	-1042.94	-1058.40
CAediting_486959	ENST00000244426.9	chr6_53099131_+	-1325.34	-1325.24	-1335.74
CAediting_486960	ENST00000244426.9	chr6_53099153_+	-1327.14	-1325.24	-1335.74
CAediting_486961	ENST00000244426.9	chr6_53099164_+	-1325.54	-1325.24	-1335.74
CAediting_486962	ENST00000244426.9	chr6_53099272_+	-1326.24	-1325.24	-1335.74
CAediting_486963	ENST00000244426.9	chr6_53099289_+	-1324.84	-1325.24	-1335.74
CAediting_486964	ENST00000244426.9	chr6_53099322_+	-1325.24	-1325.24	-1335.74
CAediting_486965	ENST00000244426.9	chr6_53099328_+	-1324.94	-1325.24	-1335.74
CAediting_486966	ENST00000244426.9	chr6_53099338_+	-1324.14	-1325.24	-1335.74
CAediting_486967	ENST00000244426.9	chr6_53099342_+	-1325.24	-1325.24	-1335.74
CAediting_486968	ENST00000244426.9	chr6_53099477_+	-1324.84	-1325.24	-1335.74
CAediting_486969	ENST00000244426.9	chr6_53099486_+	-1325.24	-1325.24	-1335.74
CAediting_486970	ENST00000244426.9	chr6_53099492_+	-1324.74	-1325.24	-1335.74
CAediting_486971	ENST00000244426.9	chr6_53099512_+	-1325.24	-1325.24	-1335.74
CAediting_486972	ENST00000244426.9	chr6_53099633_+	-1328.64	-1325.24	-1335.74
CAediting_486973	ENST00000244426.9	chr6_53099659_+	-1326.04	-1325.24	-1335.74
CAediting_486974	ENST00000244426.9	chr6_53099726_+	-1326.74	-1325.24	-1335.74
CAediting_486975	ENST00000244426.9	chr6_53100519_+	-1325.34	-1325.24	-1335.74
CAediting_486976	ENST00000244426.9	chr6_53100576_+	-1325.24	-1325.24	-1335.74
CAediting_486950	ENST00000474457.1	chr6_53090988_+	-821.64	-821.94	-845.14
CAediting_486951	ENST00000474457.1	chr6_53091004_+	-825.34	-821.94	-845.14
CAediting_486952	ENST00000474457.1	chr6_53091010_+	-827.64	-821.94	-845.14
CAediting_486953	ENST00000474457.1	chr6_53091019_+	-827.44	-821.94	-845.14
CAediting_486954	ENST00000474457.1	chr6_53091034_+	-828.54	-821.94	-845.14
CAediting_486955	ENST00000474457.1	chr6_53091462_+	-821.94	-821.94	-845.14
CAediting_486956	ENST00000474457.1	chr6_53091469_+	-821.54	-821.94	-845.14
CAediting_486957	ENST00000474457.1	chr6_53091558_+	-821.94	-821.94	-845.14
CAediting_486958	ENST00000474457.1	chr6_53091643_+	-825.34	-821.94	-845.14

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Relation with ADAR for FBXO9

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_486975	chr6_53100519_+	3.40048201311138e-07	0.257690894849008	4.7541923570647e-21	0.456909133214688	.	.
BRCA	CAediting_486975	chr6_53100519_+	5.66948689918405e-18	0.511985701390014	.	.	.	.
GBM	CAediting_486975	chr6_53100519_+	0.021241645901548	0.312893250557385	0.0299725160442709	0.295641820607353	.	.
THCA	CAediting_486975	chr6_53100519_+	0.00987878823059676	0.245034393740064	.	.	.	.
PCPG	CAediting_486975	chr6_53100519_+	9.06867337455669e-10	0.47387629190997	.	.	.	.
SKCM	CAediting_486975	chr6_53100519_+	0.004440689305613	0.374678212826758	.	.	.	.
LGG	CAediting_486976	chr6_53100576_+	0.0185178222416111	0.235153591051993	0.036397661271725	0.209551100413394	.	.
PCPG	CAediting_486976	chr6_53100576_+	0.00124717834296848	0.365854496981375	.	.	.	.

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Relation with cancer stages for FBXO9

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
THCA	pathologic_stage	CAediting_486975	chr6_53100519_+	0.00730323518792133	0.255618571827489

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Relation with survival for FBXO9

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for FBXO9

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for FBXO9

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
FBXO9	C0023893	Liver Cirrhosis, Experimental	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene