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Editing gene: FBXL4 (CAeditome ID:26235)

Gene summary for FBXL4

Gene summary

Gene information	Gene symbol	FBXL4
	Gene ID	26235
	Gene name	F-box and leucine rich repeat protein 4
	Synonyms	FBL4\|FBL5\|MTDPS13
	Cytomap	6q16.1-q16.2
	Type of gene	protein-coding
	Description	F-box/LRR-repeat protein 4
	Modification date	20210518
	UniProtAcc	Q9UKA2
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
FBXL4	GO:0005758	F-box/LRR-repeat protein 4	23993194
FBXL4	GO:0016607	F-box/LRR-repeat protein 4	0000052

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RNA A-to-I events for FBXL4

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000112234.7

RNA A-to-I editing events in Cancer.

CAediting_495314(98869355, -), CAediting_495315(98869367, -), CAediting_495316(98869368, -), CAediting_495317(98869388, -), CAediting_495318(98869403, -), CAediting_495319(98869412, -), CAediting_495320(98869414, -), CAediting_495321(98869415, -), CAediting_495322(98869467, -), CAediting_495323(98869493, -), CAediting_495324(98869498, -), CAediting_495325(98869507, -), CAediting_495326(98869520, -), CAediting_495327(98869534, -), CAediting_495328(98869542, -), CAediting_495329(98869546, -), CAediting_495330(98869547, -), CAediting_495331(98869553, -), CAediting_495332(98869577, -), CAediting_495333(98869585, -), CAediting_495334(98869603, -), CAediting_495335(98869616, -), CAediting_495336(98869624, -), CAediting_495337(98869628, -), CAediting_495338(98870819, -), CAediting_495339(98870825, -), CAediting_495340(98870837, -), CAediting_495341(98870838, -), CAediting_495342(98870870, -), CAediting_495343(98870878, -), CAediting_495344(98870902, -), CAediting_495345(98870912, -), CAediting_495346(98870913, -), CAediting_495347(98870916, -), CAediting_495348(98870919, -), CAediting_495349(98870927, -), CAediting_495350(98870954, -), CAediting_495351(98870958, -), CAediting_495352(98870960, -), CAediting_495353(98870970, -), CAediting_495354(98870973, -), CAediting_495355(98870974, -), CAediting_495356(98870982, -), CAediting_495357(98870999, -), CAediting_495358(98871000, -), CAediting_495359(98871019, -), CAediting_495360(98871035, -), CAediting_495361(98871036, -), CAediting_495362(98871044, -), CAediting_495363(98871068, -), CAediting_495364(98873605, -), CAediting_495365(98873610, -), CAediting_495366(98873681, -), CAediting_495367(98873683, -), CAediting_495368(98873688, -), CAediting_495369(98873691, -), CAediting_495370(98873694, -), CAediting_495371(98873697, -), CAediting_495372(98873707, -), CAediting_495373(98873710, -), CAediting_495374(98873714, -), CAediting_495375(98873718, -), CAediting_495376(98885359, -), CAediting_495377(98887180, -), CAediting_495378(98887183, -), CAediting_495379(98889464, -), CAediting_495380(98889490, -), CAediting_495381(98889598, -), CAediting_495382(98889605, -), CAediting_495383(98889618, -), CAediting_495384(98891642, -), CAediting_495385(98891667, -), CAediting_495386(98891668, -), CAediting_495387(98891682, -), CAediting_495388(98894066, -), CAediting_495389(98894113, -), CAediting_495390(98906293, -), CAediting_495391(98906294, -), CAediting_495392(98906298, -), CAediting_495393(98906400, -), CAediting_495394(98906401, -), CAediting_495395(98906848, -), CAediting_495396(98906849, -), CAediting_495397(98906907, -), CAediting_495398(98906971, -), CAediting_495399(98906972, -), CAediting_495400(98906984, -), CAediting_495401(98907023, -), CAediting_495402(98907027, -), CAediting_495403(98907099, -), CAediting_495404(98907121, -), CAediting_495405(98907140, -), CAediting_495406(98907143, -), CAediting_495407(98916801, -), CAediting_495408(98921584, -), CAediting_495409(98921615, -), CAediting_495410(98921619, -), CAediting_495411(98921626, -), CAediting_495412(98921627, -), CAediting_495413(98921639, -), CAediting_495414(98921644, -), CAediting_495415(98921648, -), CAediting_495416(98921695, -), CAediting_495417(98921696, -), CAediting_495418(98921699, -), CAediting_495419(98922670, -), CAediting_495420(98922681, -), CAediting_495421(98922682, -), CAediting_495422(98922716, -), CAediting_495423(98922717, -), CAediting_495424(98922718, -), CAediting_495425(98922720, -), CAediting_495426(98922723, -), CAediting_495427(98922724, -), CAediting_495428(98922725, -), CAediting_495429(98922729, -), CAediting_495430(98922735, -), CAediting_495431(98922736, -), CAediting_495432(98922747, -), CAediting_495433(98922748, -), CAediting_495434(98922752, -), CAediting_495435(98922756, -), CAediting_495436(98922759, -), CAediting_495437(98922760, -), CAediting_495438(98922761, -), CAediting_495439(98922762, -), CAediting_495440(98922763, -), CAediting_495441(98922764, -), CAediting_495442(98936525, -), CAediting_495443(98936526, -), CAediting_495444(98936533, -), CAediting_495445(98936534, -), CAediting_495446(98936535, -), CAediting_495447(98936563, -), CAediting_495448(98936575, -), CAediting_495449(98936577, -), CAediting_495450(98936584, -), CAediting_495451(98936585, -), CAediting_495452(98936595, -), CAediting_495453(98936603, -), CAediting_495454(98936604, -), CAediting_495455(98936605, -), CAediting_495456(98936609, -), CAediting_495457(98936620, -), CAediting_495458(98936625, -), CAediting_495459(98936626, -), CAediting_495460(98936688, -), CAediting_495461(98936712, -), CAediting_495462(98936716, -), CAediting_495463(98936723, -), CAediting_495464(98936729, -), CAediting_495465(98936747, -), CAediting_495466(98936825, -), CAediting_495467(98937347, -), CAediting_495468(98937376, -), CAediting_495469(98937377, -), CAediting_495470(98937434, -), CAediting_495471(98937503, -), CAediting_495472(98937504, -), CAediting_495473(98937530, -), CAediting_495474(98937592, -), CAediting_495475(98937598, -), CAediting_495476(98937599, -),

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RNA editing positional annotations for FBXL4 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_495314	chr6_98869355_-	UTR3
CAediting_495315	chr6_98869367_-	UTR3
CAediting_495316	chr6_98869368_-	UTR3
CAediting_495317	chr6_98869388_-	UTR3
CAediting_495318	chr6_98869403_-	UTR3
CAediting_495319	chr6_98869412_-	UTR3
CAediting_495320	chr6_98869414_-	UTR3
CAediting_495321	chr6_98869415_-	UTR3
CAediting_495322	chr6_98869467_-	UTR3
CAediting_495323	chr6_98869493_-	UTR3
CAediting_495324	chr6_98869498_-	UTR3
CAediting_495325	chr6_98869507_-	UTR3
CAediting_495326	chr6_98869520_-	UTR3
CAediting_495327	chr6_98869534_-	UTR3
CAediting_495328	chr6_98869542_-	UTR3
CAediting_495329	chr6_98869546_-	UTR3
CAediting_495330	chr6_98869547_-	UTR3
CAediting_495331	chr6_98869553_-	UTR3
CAediting_495332	chr6_98869577_-	UTR3
CAediting_495333	chr6_98869585_-	UTR3
CAediting_495334	chr6_98869603_-	UTR3
CAediting_495335	chr6_98869616_-	UTR3
CAediting_495336	chr6_98869624_-	UTR3
CAediting_495337	chr6_98869628_-	UTR3
CAediting_495338	chr6_98870819_-	UTR3
CAediting_495339	chr6_98870825_-	UTR3
CAediting_495340	chr6_98870837_-	UTR3
CAediting_495341	chr6_98870838_-	UTR3
CAediting_495342	chr6_98870870_-	UTR3
CAediting_495343	chr6_98870878_-	UTR3
CAediting_495344	chr6_98870902_-	UTR3
CAediting_495345	chr6_98870912_-	UTR3
CAediting_495346	chr6_98870913_-	UTR3
CAediting_495347	chr6_98870916_-	UTR3
CAediting_495348	chr6_98870919_-	UTR3
CAediting_495349	chr6_98870927_-	UTR3
CAediting_495350	chr6_98870954_-	UTR3
CAediting_495351	chr6_98870958_-	UTR3
CAediting_495352	chr6_98870960_-	UTR3
CAediting_495353	chr6_98870970_-	UTR3
CAediting_495354	chr6_98870973_-	UTR3
CAediting_495355	chr6_98870974_-	UTR3
CAediting_495356	chr6_98870982_-	UTR3
CAediting_495357	chr6_98870999_-	UTR3
CAediting_495358	chr6_98871000_-	UTR3
CAediting_495359	chr6_98871019_-	UTR3
CAediting_495360	chr6_98871035_-	UTR3
CAediting_495361	chr6_98871036_-	UTR3
CAediting_495362	chr6_98871044_-	UTR3
CAediting_495363	chr6_98871068_-	UTR3
CAediting_495364	chr6_98873605_-	UTR3
CAediting_495365	chr6_98873610_-	UTR3
CAediting_495366	chr6_98873681_-	UTR3
CAediting_495367	chr6_98873683_-	UTR3
CAediting_495368	chr6_98873688_-	UTR3
CAediting_495369	chr6_98873691_-	UTR3
CAediting_495370	chr6_98873694_-	UTR3
CAediting_495371	chr6_98873697_-	UTR3
CAediting_495372	chr6_98873707_-	UTR3
CAediting_495373	chr6_98873710_-	UTR3
CAediting_495374	chr6_98873714_-	UTR3
CAediting_495375	chr6_98873718_-	UTR3
CAediting_495376	chr6_98885359_-	intronic
CAediting_495377	chr6_98887180_-	intronic
CAediting_495378	chr6_98887183_-	intronic
CAediting_495379	chr6_98889464_-	intronic
CAediting_495380	chr6_98889490_-	intronic
CAediting_495381	chr6_98889598_-	intronic
CAediting_495382	chr6_98889605_-	intronic
CAediting_495383	chr6_98889618_-	intronic
CAediting_495384	chr6_98891642_-	intronic
CAediting_495385	chr6_98891667_-	intronic
CAediting_495386	chr6_98891668_-	intronic
CAediting_495387	chr6_98891682_-	intronic
CAediting_495388	chr6_98894066_-	intronic
CAediting_495389	chr6_98894113_-	intronic
CAediting_495390	chr6_98906293_-	intronic
CAediting_495391	chr6_98906294_-	intronic
CAediting_495392	chr6_98906298_-	intronic
CAediting_495393	chr6_98906400_-	intronic
CAediting_495394	chr6_98906401_-	intronic
CAediting_495395	chr6_98906848_-	intronic
CAediting_495396	chr6_98906849_-	intronic
CAediting_495397	chr6_98906907_-	intronic
CAediting_495398	chr6_98906971_-	intronic
CAediting_495399	chr6_98906972_-	intronic
CAediting_495400	chr6_98906984_-	intronic
CAediting_495401	chr6_98907023_-	intronic
CAediting_495402	chr6_98907027_-	intronic
CAediting_495403	chr6_98907099_-	intronic
CAediting_495404	chr6_98907121_-	intronic
CAediting_495405	chr6_98907140_-	intronic
CAediting_495406	chr6_98907143_-	intronic
CAediting_495407	chr6_98916801_-	intronic
CAediting_495408	chr6_98921584_-	intronic
CAediting_495409	chr6_98921615_-	intronic
CAediting_495410	chr6_98921619_-	intronic
CAediting_495411	chr6_98921626_-	intronic
CAediting_495412	chr6_98921627_-	intronic
CAediting_495413	chr6_98921639_-	intronic
CAediting_495414	chr6_98921644_-	intronic
CAediting_495415	chr6_98921648_-	intronic
CAediting_495416	chr6_98921695_-	intronic
CAediting_495417	chr6_98921696_-	intronic
CAediting_495418	chr6_98921699_-	intronic
CAediting_495419	chr6_98922670_-	intronic
CAediting_495420	chr6_98922681_-	intronic
CAediting_495421	chr6_98922682_-	intronic
CAediting_495422	chr6_98922716_-	intronic
CAediting_495423	chr6_98922717_-	intronic
CAediting_495424	chr6_98922718_-	intronic
CAediting_495425	chr6_98922720_-	intronic
CAediting_495426	chr6_98922723_-	intronic
CAediting_495427	chr6_98922724_-	intronic
CAediting_495428	chr6_98922725_-	intronic
CAediting_495429	chr6_98922729_-	intronic
CAediting_495430	chr6_98922735_-	intronic
CAediting_495431	chr6_98922736_-	intronic
CAediting_495432	chr6_98922747_-	intronic
CAediting_495433	chr6_98922748_-	intronic
CAediting_495434	chr6_98922752_-	intronic
CAediting_495435	chr6_98922756_-	intronic
CAediting_495436	chr6_98922759_-	intronic
CAediting_495437	chr6_98922760_-	intronic
CAediting_495438	chr6_98922761_-	intronic
CAediting_495439	chr6_98922762_-	intronic
CAediting_495440	chr6_98922763_-	intronic
CAediting_495441	chr6_98922764_-	intronic
CAediting_495442	chr6_98936525_-	intronic
CAediting_495443	chr6_98936526_-	intronic
CAediting_495444	chr6_98936533_-	intronic
CAediting_495445	chr6_98936534_-	intronic
CAediting_495446	chr6_98936535_-	intronic
CAediting_495447	chr6_98936563_-	intronic
CAediting_495448	chr6_98936575_-	intronic
CAediting_495449	chr6_98936577_-	intronic
CAediting_495450	chr6_98936584_-	intronic
CAediting_495451	chr6_98936585_-	intronic
CAediting_495452	chr6_98936595_-	intronic
CAediting_495453	chr6_98936603_-	intronic
CAediting_495454	chr6_98936604_-	intronic
CAediting_495455	chr6_98936605_-	intronic
CAediting_495456	chr6_98936609_-	intronic
CAediting_495457	chr6_98936620_-	intronic
CAediting_495458	chr6_98936625_-	intronic
CAediting_495459	chr6_98936626_-	intronic
CAediting_495460	chr6_98936688_-	intronic
CAediting_495461	chr6_98936712_-	intronic
CAediting_495462	chr6_98936716_-	intronic
CAediting_495463	chr6_98936723_-	intronic
CAediting_495464	chr6_98936729_-	intronic
CAediting_495465	chr6_98936747_-	intronic
CAediting_495466	chr6_98936825_-	intronic
CAediting_495467	chr6_98937347_-	intronic
CAediting_495468	chr6_98937376_-	intronic
CAediting_495469	chr6_98937377_-	intronic
CAediting_495470	chr6_98937434_-	intronic
CAediting_495471	chr6_98937503_-	intronic
CAediting_495472	chr6_98937504_-	intronic
CAediting_495473	chr6_98937530_-	intronic
CAediting_495474	chr6_98937592_-	intronic
CAediting_495475	chr6_98937598_-	intronic
CAediting_495476	chr6_98937599_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_495314	chr6_98869355_-	SINE	Alu	AluJb
CAediting_495315	chr6_98869367_-	SINE	Alu	AluJb
CAediting_495316	chr6_98869368_-	SINE	Alu	AluJb
CAediting_495317	chr6_98869388_-	SINE	Alu	AluJb
CAediting_495318	chr6_98869403_-	SINE	Alu	AluJb
CAediting_495319	chr6_98869412_-	SINE	Alu	AluJb
CAediting_495320	chr6_98869414_-	SINE	Alu	AluJb
CAediting_495321	chr6_98869415_-	SINE	Alu	AluJb
CAediting_495322	chr6_98869467_-	SINE	Alu	AluJb
CAediting_495323	chr6_98869493_-	SINE	Alu	AluJb
CAediting_495324	chr6_98869498_-	SINE	Alu	AluJb
CAediting_495325	chr6_98869507_-	SINE	Alu	AluJb
CAediting_495326	chr6_98869520_-	SINE	Alu	AluJb
CAediting_495327	chr6_98869534_-	SINE	Alu	AluJb
CAediting_495328	chr6_98869542_-	SINE	Alu	AluJb
CAediting_495329	chr6_98869546_-	SINE	Alu	AluJb
CAediting_495330	chr6_98869547_-	SINE	Alu	AluJb
CAediting_495331	chr6_98869553_-	SINE	Alu	AluJb
CAediting_495332	chr6_98869577_-	SINE	Alu	AluJb
CAediting_495333	chr6_98869585_-	SINE	Alu	AluJb
CAediting_495334	chr6_98869603_-	SINE	Alu	AluJb
CAediting_495335	chr6_98869616_-	SINE	Alu	AluJb
CAediting_495336	chr6_98869624_-	SINE	Alu	AluJb
CAediting_495337	chr6_98869628_-	SINE	Alu	AluJb
CAediting_495338	chr6_98870819_-	SINE	Alu	AluSz
CAediting_495339	chr6_98870825_-	SINE	Alu	AluSz
CAediting_495340	chr6_98870837_-	SINE	Alu	AluSz
CAediting_495341	chr6_98870838_-	SINE	Alu	AluSz
CAediting_495342	chr6_98870870_-	SINE	Alu	AluSz
CAediting_495343	chr6_98870878_-	SINE	Alu	AluSz
CAediting_495344	chr6_98870902_-	SINE	Alu	AluSz
CAediting_495345	chr6_98870912_-	SINE	Alu	AluSz
CAediting_495346	chr6_98870913_-	SINE	Alu	AluSz
CAediting_495347	chr6_98870916_-	SINE	Alu	AluSz
CAediting_495348	chr6_98870919_-	SINE	Alu	AluSz
CAediting_495349	chr6_98870927_-	SINE	Alu	AluSz
CAediting_495350	chr6_98870954_-	SINE	Alu	AluSz
CAediting_495351	chr6_98870958_-	SINE	Alu	AluSz
CAediting_495352	chr6_98870960_-	SINE	Alu	AluSz
CAediting_495353	chr6_98870970_-	SINE	Alu	AluSz
CAediting_495354	chr6_98870973_-	SINE	Alu	AluSz
CAediting_495355	chr6_98870974_-	SINE	Alu	AluSz
CAediting_495356	chr6_98870982_-	SINE	Alu	AluSz
CAediting_495357	chr6_98870999_-	SINE	Alu	AluSz
CAediting_495358	chr6_98871000_-	SINE	Alu	AluSz
CAediting_495359	chr6_98871019_-	SINE	Alu	AluSz
CAediting_495360	chr6_98871035_-	SINE	Alu	AluSz
CAediting_495361	chr6_98871036_-	SINE	Alu	AluSz
CAediting_495362	chr6_98871044_-	SINE	Alu	AluSz
CAediting_495363	chr6_98871068_-	SINE	Alu	AluSz
CAediting_495364	chr6_98873605_-	SINE	Alu	FAM
CAediting_495365	chr6_98873610_-	SINE	Alu	FAM
CAediting_495366	chr6_98873681_-	SINE	Alu	FAM
CAediting_495367	chr6_98873683_-	SINE	Alu	FAM
CAediting_495368	chr6_98873688_-	SINE	Alu	FAM
CAediting_495369	chr6_98873691_-	SINE	Alu	FAM
CAediting_495370	chr6_98873694_-	SINE	Alu	FAM
CAediting_495371	chr6_98873697_-	SINE	Alu	FAM
CAediting_495372	chr6_98873707_-	SINE	Alu	FAM
CAediting_495373	chr6_98873710_-	SINE	Alu	FAM
CAediting_495374	chr6_98873714_-	SINE	Alu	FAM
CAediting_495375	chr6_98873718_-	SINE	Alu	FAM
CAediting_495376	chr6_98885359_-	SINE	Alu	AluSc5
CAediting_495377	chr6_98887180_-	SINE	Alu	AluJb
CAediting_495378	chr6_98887183_-	SINE	Alu	AluJb
CAediting_495379	chr6_98889464_-	SINE	Alu	AluJb
CAediting_495380	chr6_98889490_-	SINE	Alu	AluJb
CAediting_495381	chr6_98889598_-	SINE	Alu	AluJb
CAediting_495382	chr6_98889605_-	SINE	Alu	AluJb
CAediting_495383	chr6_98889618_-	SINE	Alu	AluJb
CAediting_495384	chr6_98891642_-	SINE	Alu	FLAM_C
CAediting_495385	chr6_98891667_-	SINE	Alu	FLAM_C
CAediting_495386	chr6_98891668_-	SINE	Alu	FLAM_C
CAediting_495387	chr6_98891682_-	SINE	Alu	FLAM_C
CAediting_495388	chr6_98894066_-	SINE	Alu	AluJr
CAediting_495389	chr6_98894113_-	SINE	Alu	AluJr
CAediting_495390	chr6_98906293_-	LINE	L1	L1PA7
CAediting_495391	chr6_98906294_-	LINE	L1	L1PA7
CAediting_495392	chr6_98906298_-	LINE	L1	L1PA7
CAediting_495393	chr6_98906400_-	LINE	L1	L1PA7
CAediting_495394	chr6_98906401_-	LINE	L1	L1PA7
CAediting_495395	chr6_98906848_-	LINE	L1	L1PA7
CAediting_495396	chr6_98906849_-	LINE	L1	L1PA7
CAediting_495397	chr6_98906907_-	LINE	L1	L1PA7
CAediting_495398	chr6_98906971_-	LINE	L1	L1PA7
CAediting_495399	chr6_98906972_-	LINE	L1	L1PA7
CAediting_495400	chr6_98906984_-	LINE	L1	L1PA7
CAediting_495401	chr6_98907023_-	LINE	L1	L1PA7
CAediting_495402	chr6_98907027_-	LINE	L1	L1PA7
CAediting_495403	chr6_98907099_-	LINE	L1	L1PA7
CAediting_495404	chr6_98907121_-	LINE	L1	L1PA7
CAediting_495405	chr6_98907140_-	LINE	L1	L1PA7
CAediting_495406	chr6_98907143_-	LINE	L1	L1PA7
CAediting_495407	chr6_98916801_-	LINE	L1	L1PA3
CAediting_495442	chr6_98936525_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495443	chr6_98936526_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495444	chr6_98936533_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495445	chr6_98936534_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495446	chr6_98936535_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495447	chr6_98936563_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495448	chr6_98936575_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495449	chr6_98936577_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495450	chr6_98936584_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495451	chr6_98936585_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495452	chr6_98936595_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495453	chr6_98936603_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495454	chr6_98936604_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495455	chr6_98936605_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495456	chr6_98936609_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495457	chr6_98936620_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495458	chr6_98936625_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495459	chr6_98936626_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495460	chr6_98936688_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495461	chr6_98936712_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495462	chr6_98936716_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495463	chr6_98936723_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495464	chr6_98936729_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495465	chr6_98936747_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495466	chr6_98936825_-	DNA	TcMar-Tigger	Tigger2a
CAediting_495467	chr6_98937347_-	DNA	TcMar-Tigger	Tigger2
CAediting_495468	chr6_98937376_-	DNA	TcMar-Tigger	Tigger2
CAediting_495469	chr6_98937377_-	DNA	TcMar-Tigger	Tigger2
CAediting_495470	chr6_98937434_-	DNA	TcMar-Tigger	Tigger2
CAediting_495471	chr6_98937503_-	DNA	TcMar-Tigger	Tigger2
CAediting_495472	chr6_98937504_-	DNA	TcMar-Tigger	Tigger2
CAediting_495473	chr6_98937530_-	DNA	TcMar-Tigger	Tigger2
CAediting_495474	chr6_98937592_-	DNA	TcMar-Tigger	Tigger2
CAediting_495475	chr6_98937598_-	DNA	TcMar-Tigger	Tigger2
CAediting_495476	chr6_98937599_-	DNA	TcMar-Tigger	Tigger2

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RNA A-to-I editing events in the alternative splicing sites for FBXL4

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000112234.7.FBXL4.

Correlation between RNA A-to-I editing and PSI for ENSG00000112234.7.FBXL4.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for FBXL4

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

GBM.CAediting_495327.ENSG00000112234.FBXL4.png
Soverview

KICH.CAediting_495327.ENSG00000112234.FBXL4.png
Soverview

MESO.CAediting_495327.ENSG00000112234.FBXL4.png
Soverview

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Protein coding region RNA A-to-I editings for FBXL4

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for FBXL4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229415	chr17_67471547_+	ENSG00000112234.7	ENST00000229971	hsa-miR-548aa	98874214	98874220	7mer-m8	98874213	98874237	147	-11.92

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for FBXL4

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000369244.5	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_495314	ENST00000369244.5	chr6_98869355_-	-2085.50	-2083.20	-2152.40
CAediting_495315	ENST00000369244.5	chr6_98869367_-	-2088.80	-2083.20	-2152.40
CAediting_495316	ENST00000369244.5	chr6_98869368_-	-2084.30	-2083.20	-2152.40
CAediting_495317	ENST00000369244.5	chr6_98869388_-	-2085.00	-2083.20	-2152.40
CAediting_495318	ENST00000369244.5	chr6_98869403_-	-2084.00	-2083.20	-2152.40
CAediting_495319	ENST00000369244.5	chr6_98869412_-	-2084.90	-2083.20	-2152.40
CAediting_495320	ENST00000369244.5	chr6_98869414_-	-2085.70	-2083.20	-2152.40
CAediting_495321	ENST00000369244.5	chr6_98869415_-	-2084.00	-2083.20	-2152.40
CAediting_495322	ENST00000369244.5	chr6_98869467_-	-2085.50	-2083.20	-2152.40
CAediting_495323	ENST00000369244.5	chr6_98869493_-	-2082.80	-2083.20	-2152.40
CAediting_495324	ENST00000369244.5	chr6_98869498_-	-2082.80	-2083.20	-2152.40
CAediting_495325	ENST00000369244.5	chr6_98869507_-	-2083.20	-2083.20	-2152.40
CAediting_495326	ENST00000369244.5	chr6_98869520_-	-2083.60	-2083.20	-2152.40
CAediting_495327	ENST00000369244.5	chr6_98869534_-	-2087.10	-2083.20	-2152.40
CAediting_495328	ENST00000369244.5	chr6_98869542_-	-2082.70	-2083.20	-2152.40
CAediting_495329	ENST00000369244.5	chr6_98869546_-	-2082.90	-2083.20	-2152.40
CAediting_495330	ENST00000369244.5	chr6_98869547_-	-2082.90	-2083.20	-2152.40
CAediting_495331	ENST00000369244.5	chr6_98869553_-	-2082.50	-2083.20	-2152.40
CAediting_495332	ENST00000369244.5	chr6_98869577_-	-2082.50	-2083.20	-2152.40
CAediting_495333	ENST00000369244.5	chr6_98869585_-	-2083.20	-2083.20	-2152.40
CAediting_495334	ENST00000369244.5	chr6_98869603_-	-2082.50	-2083.20	-2152.40
CAediting_495335	ENST00000369244.5	chr6_98869616_-	-2086.80	-2083.20	-2152.40
CAediting_495336	ENST00000369244.5	chr6_98869624_-	-2083.20	-2083.20	-2152.40
CAediting_495337	ENST00000369244.5	chr6_98869628_-	-2083.90	-2083.20	-2152.40
CAediting_495338	ENST00000369244.5	chr6_98870819_-	-2082.80	-2083.20	-2152.40
CAediting_495339	ENST00000369244.5	chr6_98870825_-	-2083.20	-2083.20	-2152.40
CAediting_495340	ENST00000369244.5	chr6_98870837_-	-2086.00	-2083.20	-2152.40
CAediting_495341	ENST00000369244.5	chr6_98870838_-	-2082.90	-2083.20	-2152.40
CAediting_495342	ENST00000369244.5	chr6_98870870_-	-2085.80	-2083.20	-2152.40
CAediting_495343	ENST00000369244.5	chr6_98870878_-	-2087.60	-2083.20	-2152.40
CAediting_495344	ENST00000369244.5	chr6_98870902_-	-2087.00	-2083.20	-2152.40
CAediting_495345	ENST00000369244.5	chr6_98870912_-	-2087.40	-2083.20	-2152.40
CAediting_495346	ENST00000369244.5	chr6_98870913_-	-2083.30	-2083.20	-2152.40
CAediting_495347	ENST00000369244.5	chr6_98870916_-	-2085.10	-2083.20	-2152.40
CAediting_495348	ENST00000369244.5	chr6_98870919_-	-2083.30	-2083.20	-2152.40
CAediting_495349	ENST00000369244.5	chr6_98870927_-	-2084.10	-2083.20	-2152.40
CAediting_495350	ENST00000369244.5	chr6_98870954_-	-2083.00	-2083.20	-2152.40
CAediting_495351	ENST00000369244.5	chr6_98870958_-	-2087.00	-2083.20	-2152.40
CAediting_495352	ENST00000369244.5	chr6_98870960_-	-2086.70	-2083.20	-2152.40
CAediting_495353	ENST00000369244.5	chr6_98870970_-	-2087.50	-2083.20	-2152.40
CAediting_495354	ENST00000369244.5	chr6_98870973_-	-2084.40	-2083.20	-2152.40
CAediting_495355	ENST00000369244.5	chr6_98870974_-	-2083.20	-2083.20	-2152.40
CAediting_495356	ENST00000369244.5	chr6_98870982_-	-2082.50	-2083.20	-2152.40
CAediting_495357	ENST00000369244.5	chr6_98870999_-	-2084.40	-2083.20	-2152.40
CAediting_495358	ENST00000369244.5	chr6_98871000_-	-2083.40	-2083.20	-2152.40
CAediting_495359	ENST00000369244.5	chr6_98871019_-	-2084.40	-2083.20	-2152.40
CAediting_495360	ENST00000369244.5	chr6_98871035_-	-2083.20	-2083.20	-2152.40
CAediting_495361	ENST00000369244.5	chr6_98871036_-	-2084.00	-2083.20	-2152.40
CAediting_495362	ENST00000369244.5	chr6_98871044_-	-2085.10	-2083.20	-2152.40
CAediting_495363	ENST00000369244.5	chr6_98871068_-	-2085.40	-2083.20	-2152.40
CAediting_495364	ENST00000369244.5	chr6_98873605_-	-2087.40	-2083.20	-2152.40
CAediting_495365	ENST00000369244.5	chr6_98873610_-	-2082.90	-2083.20	-2152.40
CAediting_495366	ENST00000369244.5	chr6_98873681_-	-2083.20	-2083.20	-2152.40
CAediting_495367	ENST00000369244.5	chr6_98873683_-	-2082.30	-2083.20	-2152.40
CAediting_495368	ENST00000369244.5	chr6_98873688_-	-2089.20	-2083.20	-2152.40
CAediting_495369	ENST00000369244.5	chr6_98873691_-	-2082.60	-2083.20	-2152.40
CAediting_495370	ENST00000369244.5	chr6_98873694_-	-2082.30	-2083.20	-2152.40
CAediting_495371	ENST00000369244.5	chr6_98873697_-	-2087.90	-2083.20	-2152.40
CAediting_495372	ENST00000369244.5	chr6_98873707_-	-2082.30	-2083.20	-2152.40
CAediting_495373	ENST00000369244.5	chr6_98873710_-	-2089.40	-2083.20	-2152.40
CAediting_495374	ENST00000369244.5	chr6_98873714_-	-2082.20	-2083.20	-2152.40
CAediting_495375	ENST00000369244.5	chr6_98873718_-	-2081.90	-2083.20	-2152.40

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Relation with ADAR for FBXL4

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BLCA	CAediting_495327	chr6_98869534_-	.	.	0.00168527030276275	0.319673981863463	.	.
BRCA	CAediting_495327	chr6_98869534_-	1.8997379643451e-16	0.300075538561816	0.0203110244645022	0.0864700855452267	.	.
LIHC	CAediting_495327	chr6_98869534_-	0.00499663781063307	0.244818328449419	.	.	.	.
CESC	CAediting_495327	chr6_98869534_-	0.00154752650694454	0.352544849262982	.	.	.	.
LUAD	CAediting_495327	chr6_98869534_-	0.00169478231320105	0.222819674004751	.	.	.	.
COAD	CAediting_495327	chr6_98869534_-	0.000223897375115512	0.430304847279618	.	.	.	.
LUSC	CAediting_495327	chr6_98869534_-	4.46494922032695e-07	0.355585058427131	0.00070515968710628	0.24302566280891	.	.
PRAD	CAediting_495327	chr6_98869534_-	0.00802268482951355	0.139915172330769	3.7418627761595e-12	0.356269172461831	.	.
HNSC	CAediting_495327	chr6_98869534_-	.	.	0.000675808056071527	0.297705330655707	.	.
STAD	CAediting_495327	chr6_98869534_-	.	.	5.0604142559255e-05	0.252903184380449	.	.
THCA	CAediting_495327	chr6_98869534_-	1.59403305083149e-07	0.24780111316617	0.00128649114987227	0.153685382755813	.	.
KIRC	CAediting_495327	chr6_98869534_-	.	.	0.000661959093107588	0.165486842577719	.	.
UCEC	CAediting_495327	chr6_98869534_-	1.45752820269681e-05	0.461374544632982	.	.	.	.
KIRP	CAediting_495327	chr6_98869534_-	.	.	1.17510361037008e-07	0.43985356512887	0.0227262851602056	0.197443132839154
ESCA	CAediting_495327	chr6_98869534_-	.	.	0.00277515346073626	0.265427096770019	.	.
SKCM	CAediting_495327	chr6_98869534_-	.	.	1.15169587991306e-12	0.462101689929909	.	.
SARC	CAediting_495327	chr6_98869534_-	.	.	3.52315879931456e-08	0.513031880107215	.	.
BRCA	CAediting_495329	chr6_98869546_-	6.70828850186375e-08	0.269852774924336	.	.	.	.
LIHC	CAediting_495329	chr6_98869546_-	0.00172076269913593	0.355997317688634	.	.	.	.
LUAD	CAediting_495329	chr6_98869546_-	0.0230447668116433	0.255510159778187	.	.	.	.
STAD	CAediting_495329	chr6_98869546_-	0.0153594490103826	0.208250760213741	.	.	.	.
ESCA	CAediting_495329	chr6_98869546_-	.	.	0.00324430583571808	0.331341497736528	.	.
BRCA	CAediting_495330	chr6_98869547_-	0.00292172353666025	0.181794736670036	.	.	.	.
LUAD	CAediting_495330	chr6_98869547_-	0.00145617557152255	0.375927885645154	.	.	.	.
STAD	CAediting_495330	chr6_98869547_-	0.0476517262665253	0.203751489490071	.	.	.	.
BLCA	CAediting_495335	chr6_98869616_-	5.71505610970085e-05	0.364644538302562	.	.	.	.
BRCA	CAediting_495335	chr6_98869616_-	2.89950509130094e-11	0.243393314606434	.	.	.	.
CESC	CAediting_495335	chr6_98869616_-	0.000878919279041641	0.29980277253889	.	.	.	.
LUAD	CAediting_495335	chr6_98869616_-	0.00383215684364785	0.195084084245836	.	.	.	.
COAD	CAediting_495335	chr6_98869616_-	0.0283808193085771	0.186648676527509	.	.	.	.
LUSC	CAediting_495335	chr6_98869616_-	0.000411764520074923	0.225312788682674	.	.	.	.
PRAD	CAediting_495335	chr6_98869616_-	1.45641447925826e-09	0.308650276164405	.	.	.	.
HNSC	CAediting_495335	chr6_98869616_-	0.0382977277682771	0.158119996910248	.	.	.	.
STAD	CAediting_495335	chr6_98869616_-	0.0028602593082803	0.170778179396983	.	.	.	.
THCA	CAediting_495335	chr6_98869616_-	0.000576430729649818	0.160427057361228	.	.	.	.
UCEC	CAediting_495335	chr6_98869616_-	0.020012094495034	0.25807431863615	.	.	.	.
ESCA	CAediting_495335	chr6_98869616_-	0.0296065973507798	0.17535987982787	.	.	.	.
OV	CAediting_495335	chr6_98869616_-	3.66070563025327e-05	0.229293412968491	.	.	.	.
SKCM	CAediting_495335	chr6_98869616_-	7.4573998055449e-07	0.33752361624281	.	.	.	.
SARC	CAediting_495335	chr6_98869616_-	0.00545160789700177	0.264477809832992	.	.	.	.
THYM	CAediting_495335	chr6_98869616_-	2.37723142654296e-05	0.528546188208304	.	.	.	.
BRCA	CAediting_495364	chr6_98873605_-	2.22049376349316e-06	0.237561991204837	.	.	.	.
LUAD	CAediting_495364	chr6_98873605_-	0.000184784597838502	0.380262039697425	.	.	.	.
LUSC	CAediting_495364	chr6_98873605_-	0.00687924428000903	0.274122456052639	.	.	.	.
PRAD	CAediting_495364	chr6_98873605_-	5.34467008092692e-05	0.3428709617168	.	.	.	.
STAD	CAediting_495364	chr6_98873605_-	.	.	0.00610152031159999	0.230697984418069	.	.
THCA	CAediting_495364	chr6_98873605_-	2.15618597986579e-06	0.338479001200169	.	.	.	.
ESCA	CAediting_495364	chr6_98873605_-	0.00903602202131385	0.273739543587858	.	.	.	.
SKCM	CAediting_495364	chr6_98873605_-	0.0276743997223594	0.282005848498541	0.023540042127756	0.289691691131682	.	.
BRCA	CAediting_495371	chr6_98873697_-	0.000779300362235734	0.153980069987662	0.000126943061133484	0.175307447578083	.	.
LUSC	CAediting_495371	chr6_98873697_-	0.000106243580222672	0.347812608470904	0.0274951621581343	0.202121360130227	.	.
PRAD	CAediting_495371	chr6_98873697_-	.	.	8.36132432824319e-06	0.311504495692445	.	.
HNSC	CAediting_495371	chr6_98873697_-	.	.	0.0116567935433536	0.28795129866311	.	.
STAD	CAediting_495371	chr6_98873697_-	.	.	4.01302718167698e-07	0.424165781966384	.	.
THCA	CAediting_495371	chr6_98873697_-	6.33907459331105e-06	0.300412161663175	0.0197609172026728	0.157782507789406	.	.
KIRP	CAediting_495371	chr6_98873697_-	.	.	0.00279849285441439	0.373376298034832	.	.
ESCA	CAediting_495371	chr6_98873697_-	.	.	0.0235522522388388	0.257883883531125	.	.
SKCM	CAediting_495371	chr6_98873697_-	.	.	0.00659497382949584	0.258742513447288	.	.
LGG	CAediting_495373	chr6_98873710_-	.	.	0.0355185542682526	0.17416054831873	.	.
BRCA	CAediting_495373	chr6_98873710_-	4.87879544180343e-06	0.189266101387864	0.000375425391678367	0.147833995418621	.	.
LUAD	CAediting_495373	chr6_98873710_-	0.0333652066722374	0.176220766229522	.	.	.	.
LUSC	CAediting_495373	chr6_98873710_-	0.000108181875713041	0.297704246156936	0.000197630870169102	0.286708542586573	.	.
PRAD	CAediting_495373	chr6_98873710_-	.	.	3.59434185779423e-11	0.41609610519428	.	.
HNSC	CAediting_495373	chr6_98873710_-	0.0388200352190709	0.201006610311755	4.24065038930464e-05	0.386645785569355	.	.
STAD	CAediting_495373	chr6_98873710_-	.	.	2.31304448139787e-05	0.328855005054071	.	.
THCA	CAediting_495373	chr6_98873710_-	1.95894107585732e-06	0.299109472204721	.	.	.	.
KIRC	CAediting_495373	chr6_98873710_-	0.00360916507680479	0.153233558342572	0.000249688919216408	0.192169045777506	.	.
KIRP	CAediting_495373	chr6_98873710_-	.	.	0.00168426379879431	0.356663585384136	.	.
SKCM	CAediting_495373	chr6_98873710_-	.	.	0.00672060074422582	0.237522491112299	.	.
SARC	CAediting_495373	chr6_98873710_-	0.0371362856011187	0.289844522646606	0.0181253926205908	0.326593035510061	.	.

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Relation with cancer stages for FBXL4

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_495335	chr6_98869616_-	0.00363935684979483	0.269077197946823
KIRC	pathologic_stage	CAediting_495327	chr6_98869534_-	0.00629134415178381	0.133437620528603
KIRC	pathologic_stage	CAediting_495335	chr6_98869616_-	0.0264459256149122	0.108828902871314
LUAD	pathologic_stage	CAediting_495330	chr6_98869547_-	0.0133770427571927	0.300820555856399
LUSC	pathologic_stage	CAediting_495335	chr6_98869616_-	0.0162732412891711	0.155289775853379
OV	clinical_stage	CAediting_495327	chr6_98869534_-	0.0358382679208133	0.130232107916534
STAD	pathologic_stage	CAediting_495330	chr6_98869547_-	0.0108940697186949	-0.265757330023468
THCA	pathologic_stage	CAediting_495327	chr6_98869534_-	0.0146212561145921	0.117678860629019
THCA	pathologic_stage	CAediting_495330	chr6_98869547_-	0.0462284129071019	0.165822053626293
THCA	pathologic_stage	CAediting_495335	chr6_98869616_-	0.00786187347077462	0.12501333065542
THCA	pathologic_stage	CAediting_495371	chr6_98873697_-	0.0421576429369775	0.138716537805048
UCEC	clinical_stage	CAediting_495335	chr6_98869616_-	0.0290175064600067	-0.242715772269106

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Relation with survival for FBXL4

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for FBXL4

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for FBXL4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
FBXL4	C3809592	FBXL4-related encephalomyopathic mitochondrial DNA depletion syndrome	5	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
FBXL4	C0036572	Seizures	1	GENOMICS_ENGLAND

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene